Mass Drug Distribution Strategy Efficacy for Schistosomiasis Control in Mali (West Africa)

2021 ◽  
Author(s):  
Abdoulaye Dabo ◽  
Mouctar Diallo ◽  
Privat Koba Agniwo ◽  
Salim Danté ◽  
Assitan Traoré ◽  
...  
Keyword(s):  
Schistosoma Haematobium ◽  
Drug Distribution ◽  
Public Health Problem ◽  
Cross Sectional Study ◽  
Major Public Health Problem ◽  
Cross Sectional ◽  
Transmission Cycle ◽  
Heavy Infection ◽  
Girls School ◽  
The Impact

Abstract Background - Schistosomiasis is a water-based parasitic disease caused by blood flukes of the genus Schistosoma. Mass Drug Distribution (MDD) with Praziquantel is periodically recommended in schistosomiasis-endemic countries to prevent morbidity. In Mali, schistosomiasis still remains endemic, especially in Senegal and Niger rivers basin, although the strategy has been adopted since 2005. Our study aimed to assess the impact of annual school-based MDD. Materials and methods – The study was conducted at twelve sentinel sites across Kayes and Koulikoro regions. A cross-sectional study design was performed in April 2018 after four-or five-years post treatment with praziquantel (PZQ) depending on the statute of sites. At baseline (2014-2015) and for the control year (2018), 734 (386 boys and 347 girls) and 1708 (844 boys and 864 girls) school children of 7-14 years of age, were successfully examined respectively. Infections with Schistosoma haematobium and S. mansoni were diagnosed with the urine filtration and the Kato-Katz method respectively. Results – From eight schools treated in 2014, the four annual rounds of MDD with PZQ were associated with a significant decrease in S. haematobium prevalence in five sites (p<0,001) and a significant increase in one site (p<0,001). Of them, the prevalence of high-intensity (≥50 eggs/10mL of urine) significantly decreased in four previous sites but not in Diakalele where it increased ((p<0.001). In all the four sites treated in 2015, S. haematobium prevalence increased significantly in Kokoun and Samaya (P<0.05). The heavy infection increased slightly in Dougourakoro and Samaya (P>0.05). The prevalence of S. mansoni significantly decreased in three sites (p<0.001), increased in three and remains zero in the six others sites. Conclusion – Our findings show that five of the twelve sentinel sites have achieved the criterion of elimination of schistosomiasis due to Schistosoma haematobium as a major public health problem (Prevalence of heavy infection <1%); three have achieved the criterion of morbidity control (Prevalence of heavy infection <5%), whereas two sites remain confined below the control criterion. These results call for a strong improvement in the therapeutic coverage associating, education and provision of safe water, sanitation and hygiene to interrupt the transmission cycle of the schistosome.

Status of Schistosoma haematobium Infection among Pupils around the Kainji Dam, Niger State: A Paradigm Shift In Infection Rate

2020 ◽  
Vol 41 (2) ◽  
Author(s):  
B Adewale ◽  
O Rahman ◽  
M Sulyman ◽  
C Uwalaka ◽  
M Ajayi
Keyword(s):  
Paradigm Shift ◽  
Schistosoma Haematobium ◽  
Geometric Mean ◽  
Public Health Problem ◽  
Cross Sectional Study ◽  
Current Status ◽  
Major Public Health Problem ◽  
Cross Sectional ◽  
Significant Difference ◽  
The Impact

Schistosomiasis is the second most prevalent tropical disease after malaria, and a major public health problem among schoolagedchildren. This study was carried out to assess the current status of Schistosoma haematobium infection among pupils around Kainji Dam. A cross-sectional study was carried out in 5 communities around Kainji dam. Urine samples were collected and processed using the standard filtration technique. Filter papers were examined with compound microscope and eggs of S. haematobium were identified with their terminal spines. Data were analyzed with SPSS 23. The overall prevalence of Schistosoma haematobium infection among the 410 pupils examined was 5.1% and a geometric mean egg count of 5.97 eggs/10ml urine. There was statistically significant association between infection and age with peak infection in age group 12-14 (11.8%, x2 = 14.185, p < 0.005). The males (6.8%) were more infected than the females (2.9%) and there was no significant difference (Χ² =3.1, P>0.05) in infection among sexes. The occupation of Pupils' Parent was found to have a statistically significant association with the risk of being infected (x2 = 38.7, P<0.05), prevalence of infection was shared between the fishermen (47.6%) and farmers (52.4%). Compared to other studied communities, a pupil stands over 400times [OR 412.2 (95% CI: 52.4 – 3245.1)] risk of being infected with Schistosoma haematobium in Yuna community. The lack of infection in 3 of the studied communities could be attributed to the impact of current efforts at controlling Schistosoma haematobium infection around the Kainji dam which is a paradigm shift from what used to be experienced from previous studies. This current experience advocates for intensified efforts at total elimination. Keywords: Schistosoma haematobium, Prevalence, Pupils, Kainji dam

scholarly journals Characterization ofMycobacterium bovisfrom Humans and Cattle in Namwala District, Zambia

2014 ◽  
Vol 2014 ◽  
pp. 1-7 ◽  
Author(s):  
Sydney Malama ◽  
Tone Bjordal Johansen ◽  
John Bwalya Muma ◽  
Musso Munyeme ◽  
Grace Mbulo ◽  
...  
Keyword(s):  
Public Health ◽  
Public Health Problem ◽  
Epidemiological Studies ◽  
Cross Sectional Study ◽  
Major Public Health Problem ◽  
Infected Cattle ◽  
Sectional Study ◽  
Cross Sectional ◽  
The Impact

Tuberculosis remains a major public health problem in Zambia. While human to human transmission ofMycobacterium tuberculosisis of major importance in driving the tuberculosis epidemic, the impact ofMycobacterium bovistransmission from infected cattle is largely unknown. This cross-sectional study aimed at molecular characterization ofM. bovisin humans and cattle. A total of 100 human sputum samples and 67 bovine tissues were collected and analyzed for the presence of mycobacteria. Of 65 human samples that harbored acid fast bacteria (AFB), 55 isolates were obtained of which 34 were identified asM. tuberculosisand 2 asM. bovis. AFB-positive bovine samples (n=67) yielded 47 mycobacterial isolates among which 25 were identified asM. bovisand noM. tuberculosiswas found. Among theM. bovisisolates, spoligotyping revealed a high homogeneity in genotypes circulating in Namwala district. Human and cattle isolates shared identical MIRU-VNTR genotypes, suggesting that transmission between the two hosts may occur. Therefore, this study has documented zoonotic TB in human patients in Namwala district of Zambia. However, further molecular epidemiological studies in the study area are recommended.

scholarly journals A study on health and nutritional status of children in rural and urban ICDS projects in Karimnagar

2019 ◽  
Vol 6 (4) ◽  
pp. 1747
Author(s):  
Anil Moluguri ◽  
Dasari Gayathry ◽  
Sachin Gurnule
Keyword(s):  
Public Health Problem ◽  
Total Sample ◽  
Cross Sectional Study ◽  
Preschool Age ◽  
Major Public Health Problem ◽  
Cross Sectional ◽  
Rural And Urban ◽  
High Prevalence ◽  
Nutritional Status Of Children ◽  
The Impact

Background: Malnutrition is a major public health problem. It continues to be a primary cause of ill health and mortality among children in developing countries. Preschool age is an important stage of life where the nutrition plays an important role and has long lasting effects in the later years of life. Hence the objective of the present study was to assess the nutritional and health status of under-five children covered under the ICDS project.Methods: A cross-sectional study was conducted during March 2013-February 2014 among 846 children attending the rural and urban anganwadi centers of Karimnagar ICDS project. A semi-structured questionnaire was used to collect data and was analyzed using Epi info version 7 and valid inferences were drawn.Results: It was observed in the present study that females (53.5%) were more compared to boys (46.5%), out of the total sample surveyed. In this study 87.6% were completely immunized and 12.4% were partially immunized. According to IAP classification of malnutrition, 27.7% children were mildly malnourished, 16.5% were moderately malnourished, 3.9 % were severely malnourished and 0.9 % was very severely malnourished.Conclusions: High prevalence of malnutrition was observed among children in both urban and rural area warrants urgent attention. ICDS projects should be periodically studied to evaluate the impact of interventions. Further exploratory studies are required to find of several risk factors of malnutrition.

scholarly journals Impact of COVID-19 Home Confinement in Children’s Refractive Errors

2021 ◽  
Vol 18 (10) ◽  
pp. 5347
Author(s):  
Cristina Alvarez-Peregrina ◽  
Clara Martinez-Perez ◽  
Cesar Villa-Collar ◽  
Cristina Andreu-Vázquez ◽  
Alicia Ruiz-Pomeda ◽  
...  
Keyword(s):  
Public Health Problem ◽  
Cross Sectional Study ◽  
World Population ◽  
Sectional Study ◽  
Cross Sectional ◽  
School Aged Children ◽  
Digital Devices ◽  
Visual Screening ◽  
Near Work ◽  
The Impact

Background: Myopia is a public health problem, with estimations that 50% of the world population will be myopic by 2050. Some environmental factors, such as time spent outdoors, doing near work, and using digital devices, influence the development of myopia in children. Home confinement in Spain has increased these risk factors, so this study aims to investigate the impact of home confinement during the COVID-19 outbreak in the vision of school-aged children; Methods: A cross-sectional study in children between 5 and 7 years old that completed a visual screening and a questionnaire about their lifestyles at opticians in Spain in September and October of 2019 and 2020. Statistical analysis to compare lifestyles pre and post confinement, and vision in 2020 versus a similar cohort examined at the same opticians in 2019, was conducted; Results: Spanish children spent less time outdoors and more time doing near work in 2020 than in 2019 (p ≤ 0.001). There was a significant decrease of the spherical equivalent (mean ± standard deviation; 0.66 ± 2.03 D in 2019 vs. 0.48 ± 1.81 D in 2020; p ≤ 0.001); Conclusions: Lifestyles of Spanish children changed during the home confinement at the beginning of 2020. Together with changes in their lifestyles, spherical equivalents have decreased, which implies higher figures of myopia for children aged between 5 and 7.

scholarly journals The prescription pattern and awareness about antibiotic prophylaxis and resistance among a group of Egyptian pediatric and general dentists: a cross sectional study

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Mariam Mohsen Aly ◽  
Marwa Aly Elchaghaby
Keyword(s):  
Antibiotic Resistance ◽  
Antibiotic Prophylaxis ◽  
Antibiotic Prescription ◽  
Public Health Problem ◽  
Cross Sectional Study ◽  
Major Public Health Problem ◽  
Eligibility Criteria ◽  
Cross Sectional ◽  
Validated Questionnaire ◽  
General Dentists

Abstract Background The use of antibiotics in dentistry as prophylaxis and treatment is frequent. Their misuse has led to a major public health problem globally known as antibiotic resistance. This study aimed to assess the pattern of antibiotic prescription and its prophylactic use for systemic conditions. Besides, this study evaluated the awareness and adherence to antibiotic prescription guidelines and antibiotic prophylaxis guidelines along with awareness of antibiotic resistance across pediatric and general dentists. Methods An overall of 378 pediatric and general dentists meeting the required eligibility criteria, fulfilled a pre-designed validated questionnaire. Data were collected, tabulated, and statistically analyzed. Results A significant statistical difference was found among the pediatric and general dentists regarding antibiotics prescription for most of the oral conditions where Amoxicillin with clavulanic acid was the most frequently prescribed antibiotic among the two groups (53% pediatric dentist and 52% general dentist). The majority of pediatric and general dentists, on the other hand, were aware of antibiotic resistance and prescribing recommendations. Conclusions The present study showed a tendency to overprescribe and overuse antibiotics in certain dental conditions among the participants. The vast majority of dentists, especially general dentists do not have adherence to professional guidelines for antibiotics prescription in children despite their awareness of antibiotic resistance and prescription guidelines.

scholarly journals A study on mosquito density in rural Kerala before and after floods

2019 ◽  
Vol 6 (2) ◽  
pp. 659
Author(s):  
V. T. Krishnadas Menon ◽  
Jerry Rachel ◽  
C. R. Saju ◽  
M. Mohamed Rafi ◽  
Vidhu M. Joshy
Keyword(s):  
Disease Outbreaks ◽  
Public Health Problem ◽  
Cross Sectional Study ◽  
Major Public Health Problem ◽  
Mosquito Density ◽  
Cross Sectional ◽  
Training Centre ◽  
Before And After ◽  
Initial Survey ◽  
Rural Training

Background: Mosquito borne diseases are a major public health problem in Kerala. Mosquito density assessed by larval surveys is easier and quicker to perform. The larval indices are an important practical predictor of outbreaks of mosquito borne disease and are valuable in taking preventive measures. This study is done to calculate standardized larval indices namely house index, container index and Breteau index and to identify the major breeding sources of mosquitoes in the residential environment in a rural of Thrissur, Kerala.Methods: A cross-sectional study selecting 80 houses from 1 wards of Konnikara village under Thrikkur Panchayath under the field practice area of rural training centre, Amala Institute of Medical Sciences Thrissur. Every water holding container indoors and outdoors was counted and searched for larval presence and noted on a pretested format.Results: In this study, 80 houses were surveyed in 2 days initially in June and in September. All the entomological indices were found to be above the critical level in the initial survey in June. House index=36% container index=44%; Breteau index=143% showing high chances for outbreaks of mosquito borne diseases. In September though the indices were very low house index 1.25% container index 2.77% and Breteau index.Conclusions: The area is prone for mosquito borne disease outbreaks like dengue fever and after interventions the vector indices and potential risks came down.

scholarly journals “A STUDY OF MICROALBUMINURIA IN NON DIABETIC HYPERTENSIVE PATIENTS”

2020 ◽  
pp. 1-3
Author(s):  
Anup Latne ◽  
Prabhakar Jirvankar
Keyword(s):  
Cardiovascular Risk ◽  
Tertiary Care ◽  
Public Health Problem ◽  
Cross Sectional Study ◽  
Low Grade ◽  
Major Public Health Problem ◽  
Sectional Study ◽  
Tertiary Care Centre ◽  
Cross Sectional ◽  
Hypertensive Patients

Hypertension is a major public health problem all over the world. The incidence of hypertension is increasing year after year and the prevalence of hypertension is increasing day by day due to increased life expectancy and aging population and their sedentary lifestyle. Hypertension is known to cause microvascular changes and increased cardiovascular risk from it. Microalbuminuria possibly reflects a state of increased renal endothelial permeability and is an easily measured marker of rather diffuse endothelial dysfunction, low grade inflammation and vascular disease burden2. Microalbuminuria has been determined as an important prognostic indicator and has been reported to be associated with increased cardiovascular risk and progressive renal damage. Reliable data on the prevalence of microalbuminuria in the general population and its association with cardiovascular risk factors is limited. Till now, there is little data available regarding screening and early treatment of hypertensive patients with microalbuminuria, as in the case of microalbuminuric non diabetic subjects. With these perspective this cross sectional study of microalbuminuria in non-diabetic hypertensive patients was undertaken to study prevalence of microalbuminuria in Non Diabetic hypertensive patients. Objectives: To determine the prevalence of microalbuminuria in non-diabetic hypertensive patients and to correlate the presence of microalbuminuria with the patients of different clinical profiles. Materials and Methods: This was observational, cross sectional study of Patients diagnosed with hypertension either admitted in ward or attending OPD of Medical College and Tertiary Care Centre. Urine microalbumin creatinine ratio was used for estimation of microalbuminuria. Conclusion: It was proved that microalbuminuria prevalence was directly proportional to the duration of hypertension, the stage of hypertension. Prevalence of microalbuminria was low in ACE inhibitor and ARB treated hypertensive patients.

scholarly journals Opportunistic Infections and Associated Factors among HIV/AIDS Patients taking Ante-Retroviral Therapy at Selected Hospitals in Sidama Zone, Southern Ethiopia: A facility-based cross-sectional study

2019 ◽  
Author(s):  
Demelash Wachamo ◽  
Fisseha Bonja
Keyword(s):  
Associated Factors ◽  
Opportunistic Infections ◽  
Public Health Problem ◽  
Cross Sectional Study ◽  
High Morbidity ◽  
Major Public Health Problem ◽  
Sectional Study ◽  
Aids Patients ◽  
Cross Sectional ◽  
Hiv Aids

Abstract Background Opportunistic infections are late complications of HIV infection is the depletion of the immune system. It is a major public health problem and high morbidity AIDS patients die of AIDS-related infections in developing countries like Ethiopia. Identification of opportunistic infections (OIs) is important to develop a specific intervention. Therefore, this study aimed to assess the burden and associated factors of opportunistic infections.Method A facility-based cross-sectional study was conducted on 420 randomly selected HIV/AIDS patients taking anti-retroviral therapy. Data was collected from selected hospitals in Sidama Zone based on population proportion to size. Data was collected by a pre-tested questionnaire and a pre-tested checklist from the medical records of patients. Data entry and analyzed for descriptive and logistic regression models by SPSS v.23. The result declared as statistically significant at p < 0.05.Result The magnitude of opportunistic infections was 39.6%. Major identified OIs was oral candidacies 23.2%, recurrent bacterial pneumonia 21.5%, Herpes zoster 6.3%, and Pulmonary Tuberculosis 6.0%.The magnitude of opportunistic associated with; older age [AOR=2.69, 95% CI: 1.33-5.43], No formal education [AOR=3.12, 95% CI: 1.06-9.25], Low monthly income [AOR=2.27, 95%CI:1.35-3.83], initial CD4 count less than 200 cells/mm3 [AOR=1.91, 95% CI:1.05-3.46), WHO clinical stage II [AOR=2.43, 95% CI:1.34-4.42] and stage III and IV [AOR=4.27, 95% CI: 2.12-8.59], had no extra medicine additional to ART (prophylaxis) had [AOR= 5.91, 95% CI: 3.31-10.56], who interrupt ART medicines [AOR=2.03, 95% CI: 1.09- 3.80] and Khat chewing [AOR=5.48, 95% CI: 2.32-12.96] when compared to their counterparts.Conclusions The overall magnitude of opportunistic infections was high when compared with other studies. Health officials and clinicians need to give attention on the strengthening of the provision if ART with prophylaxis on early-stage and adhrerence, implementation of the TB/HIV collaboration activity, and early initiation of ART to reduce opportunistic infections.

scholarly journals Prevalence of anaemia and visual impairment among primary school children of South Gujarat region of India: a cross sectional study

2019 ◽  
Vol 7 (1) ◽  
pp. 30
Author(s):  
Bharatkumar Balkrishna Pandya ◽  
Upendrakumar Rameshbhai Chaudhari ◽  
Avirat A. Bhatt ◽  
Nilesh Thakor
Keyword(s):  
Visual Impairment ◽  
Public Health Problem ◽  
Cross Sectional Study ◽  
Primary School Children ◽  
School Age Children ◽  
Major Public Health Problem ◽  
Sectional Study ◽  
Cross Sectional ◽  
Nutritional Anemia ◽  
Prevalence Of Anemia

Background: Nutritional Anemia and visual impairment among school age children are recognized as major public health problem in India. Authors objective was to study prevalence of anemia and visual impairment among school going adolescents of Vadodara and Surat city of Gujarat, India.Methods: This cross sectional study was carried during period from April 2015 to March 2016. Total 8 schools were selected from Vadodara and Surat city by purposive sampling. After taking the permission of principals of schools and informed written consent of the parents of children, 859 children from these schools were examined for anaemia and visual impairment. The data was collected by predesign, pretested proforma and analysed using SPSS version 17 (Trial version).Results: Out of total 859 children 421(49.1%) were female. Mean age of the study children was 8.95±1.52 years. The prevalence of anemia in children in present study was 61.6 % (529 children). The prevalence of anemia in female (274, 65.1%) was higher than males (255, 58.2%). Moderate visual impairment and blindness was 5.9% in girls and 8.2% in boys respectively. Severe visual impairment and blindness was 2.1% in girls and 2.7% in boys respectively and the gender difference was not statistically significant. Though 61(7.1%) children had moderate to severe visual impairment to blindness only 21 (2.4%) children were wearing spectacles.Conclusions: High prevalence of anaemia and visual impairment among these children needs great attention and health education.

scholarly journals Assessment of General Public’s Knowledge and Opinions towards Antibiotic Use and Bacterial Resistance: A Cross-Sectional Study in an Urban Setting, Rufisque, Senegal

Pharmacy ◽  
2018 ◽  
Vol 6 (4) ◽  
pp. 103 ◽  
Author(s):  
Oumar Bassoum ◽  
Ndèye Sougou ◽  
Mayassine Diongue ◽  
Mamadou Lèye ◽  
Mouhamad Mbodji ◽  
...  
Keyword(s):  
Bacterial Resistance ◽  
Public Health Problem ◽  
Antibiotic Use ◽  
Cross Sectional Study ◽  
Urban Setting ◽  
Major Public Health Problem ◽  
Sources Of Information ◽  
Sectional Study ◽  
Cross Sectional ◽  
Awareness Campaigns

Background: Bacterial resistance is a major public health problem worldwide. One solution to this scourge is to sensitize the general public on rational use of antibiotics. Our goal was to assess people’s knowledge and opinions about antibiotic use and bacterial resistance in an urban setting. Method: We performed a cross-sectional study. A convenience sampling was done. A questionnaire was administered to 400 persons during face-to-face interviews. Results: Most respondents thought that antibiotics are effective against colds/flu (69.8%), cough (72.3%) and sore throat (64.4%). At the same time, 42.8% stated that antibiotic therapy can be stopped as soon as the symptoms disappear. Only 8.8% and 41.8% of people knew that handwashing and vaccination prevented bacterial resistance. Globally, 7% of people had a good knowledge. Socio-demographic variables were not associated with the level of knowledge. The main sources of information were entourage and pharmacy staff. Regarding the opinions, 78.3% of surveyed participants the people thought that that people overuse antibiotics. Additionally, 28% said that they have no role to play against bacterial resistance. Conclusion: People living in an urban setting had a low knowledge about antibiotic use and bacterial resistance. There is a need to implement awareness campaigns. Further studies on population practices toward antibiotic use are necessary.

Sign in / Sign up

Export Citation Format

Share Document