scholarly journals Reactive Oxygen Spices Scavenging Behavior of Selenium Upon Vinyl Chloride Interaction With Hemoglobin

2021 ◽  
Author(s):  
Negar Hajimohammadi Oushani ◽  
Masoumeh Valipour ◽  
Parvaneh Maghami
Keyword(s):  
Vinyl Chloride ◽  
Oxygen Transfer ◽  
Vital Role ◽  
The Body ◽  
Ros Production ◽  
Molecular Aspect ◽  
Pleasant Odor ◽  
Uv Visible ◽  
Chloride Interaction ◽  
Vital Factor

Abstract BackgroundVinyl chloride (VC) a colorless gas with a pleasant odor that is capable of entering the body through oral or inhalation routes. Extensive studies on this compound indicated that it is a carcinogen, and Vinyl chloride exposure can result in a specific type of cancer in VC workers. Whereas hemoglobin plays a vital role in oxygen transfer throughout the body, the effect of VC on human hemoglobin has not been studied in a molecular aspect. Furthermore, selenium as an antioxidant is a vital factor for the health of humans and animals. Therefore, the effect of the antioxidant capability of selenium on the interaction between vinyl chloride and hemoglobin was studied.MethodsThe effect of the antioxidant capability of selenium on the interaction between VC and hemoglobin was investigated by different spectroscopy methods such as UV-visible, Fourier-transform infrared, chemiluminescence, and fluorescence spectroscopies and molecular dockingResultsThe results indicated the destruction of hemoglobin structure in the presence of different concentrations of vinyl chloride, but in the presence of selenium, the damaging effect of VC on hemoglobin structure was decreased, relying on its antioxidant capability results.ConclusionsAccording to our findings, vinyl chloride destroyed hemoglobin structure utilizing ROS production, and the presence of selenium as an antioxidant inhibits the destroying effect of vinyl chloride on hemoglobin

scholarly journals The Mechanism of Secretion and Metabolism of Gut-Derived 5-Hydroxytryptamine

2021 ◽  
Vol 22 (15) ◽  
pp. 7931
Author(s):  
Ning Liu ◽  
Shiqiang Sun ◽  
Pengjie Wang ◽  
Yanan Sun ◽  
Qingjuan Hu ◽  
...  
Keyword(s):  
Cell Metabolism ◽  
Circulatory System ◽  
Vital Role ◽  
The Body ◽  
Neuroendocrine Cells ◽  
Intestinal Lumen ◽  
Paracrine Signaling ◽  
Inflammatory Conditions ◽  
Epithelial Development ◽  
Ec Cells

Serotonin, also known as 5-hydroxytryptamine (5-HT), is a metabolite of tryptophan and is reported to modulate the development and neurogenesis of the enteric nervous system, gut motility, secretion, inflammation, sensation, and epithelial development. Approximately 95% of 5-HT in the body is synthesized and secreted by enterochromaffin (EC) cells, the most common type of neuroendocrine cells in the gastrointestinal (GI) tract, through sensing signals from the intestinal lumen and the circulatory system. Gut microbiota, nutrients, and hormones are the main factors that play a vital role in regulating 5-HT secretion by EC cells. Apart from being an important neurotransmitter and a paracrine signaling molecule in the gut, gut-derived 5-HT was also shown to exert other biological functions (in autism and depression) far beyond the gut. Moreover, studies conducted on the regulation of 5-HT in the immune system demonstrated that 5-HT exerts anti-inflammatory and proinflammatory effects on the gut by binding to different receptors under intestinal inflammatory conditions. Understanding the regulatory mechanisms through which 5-HT participates in cell metabolism and physiology can provide potential therapeutic strategies for treating intestinal diseases. Herein, we review recent evidence to recapitulate the mechanisms of synthesis, secretion, regulation, and biofunction of 5-HT to improve the nutrition and health of humans.

scholarly journals Kidney Inflammation, Injury and Regeneration 2020

2021 ◽  
Vol 22 (11) ◽  
pp. 5589
Author(s):  
Patrick C. Baer ◽  
Benjamin Koch ◽  
Helmut Geiger
Keyword(s):  
Vital Role ◽  
The Body ◽  
Physiological Functions

The kidneys play a vital role in the basic physiological functions of the body [...]

scholarly journals Age-Related, Sport-Specific Adaptions of the Shoulder Girdle in Elite Adolescent Tennis Players

2014 ◽  
Vol 49 (5) ◽  
pp. 647-653 ◽  
Author(s):  
Ann M. Cools ◽  
Tanneke Palmans ◽  
Fredrik R. Johansson
Keyword(s):  
Muscle Strength ◽  
Shoulder Girdle ◽  
Vital Role ◽  
The Body ◽  
Injury Incidence ◽  
Shoulder Injury ◽  
Serratus Anterior ◽  
Cross Sectional ◽  
Tennis Players ◽  
Age Related

Context Tennis requires repetitive overhead movements that can lead to upper extremity injury. The scapula and the shoulder play a vital role in injury-free playing. Scapular dysfunction and glenohumeral changes in strength and range of motion (ROM) have been associated with shoulder injury in the overhead athlete. Objective To compare scapular position and strength and shoulder ROM and strength between Swedish elite tennis players of 3 age categories (<14, 14–16, and >16 years). Design Cross-sectional study. Setting Tennis training sports facilities. Patients or Other Participants Fifty-nine adolescent Swedish elite tennis players (ages 10–20 years) selected based on their national ranking. Main Outcome Measure(s) We used a clinical screening protocol with a digital inclinometer and a handheld dynamometer to measure scapular upward rotation at several angles of arm elevation, isometric scapular muscle strength, glenohumeral ROM, and isometric rotator cuff strength. Results Players older than 16 years showed less scapular upward rotation on the dominant side at 90° and 180° (P < .05). Although all absolute scapular muscle strength values increased with age, there was no change in the body-weight–normalized strength of the middle (P = .9) and lower (P = .81) trapezius or serratus anterior (P = .17). Glenohumeral internal-rotation ROM and total ROM tended to decrease, but this finding was not statistically significant (P = .052 and P = .06, respectively). Whereas normalized internal-rotator strength increased from 14 to 16 years to older than 16 years (P = .009), normalized external-rotator and supraspinatus strength remained unchanged. Conclusions Age-related changes in shoulder and scapular strength and ROM were apparent in elite adolescent tennis players. Future authors should examine the association of these adaptations with performance data and injury incidence.

Investigating the citation advantage of author-pays charges model in computer science research: a case study of Elsevier and Springer

2021 ◽  
Vol ahead-of-print (ahead-of-print) ◽  
Author(s):  
Tehmina Amjad ◽  
Mehwish Sabir ◽  
Azra Shamim ◽  
Masooma Amjad ◽  
Ali Daud
Keyword(s):  
Open Access ◽  
Computer Science ◽  
Science Research ◽  
Vital Role ◽  
The Body ◽  
Content Type ◽  
Body Of Knowledge ◽  
Computer Science Research ◽  
Science Domain ◽  
Citation Advantage

PurposeCitation is an important measure of quality, and it plays a vital role in evaluating scientific research. However, citation advantage varies from discipline to discipline, subject to subject and topic to topic. This study aims to compare the citation advantage of open access and toll access articles from four subfields of computer science.Design/methodology/approachThis research studies the articles published by two prestigious publishers: Springer and Elsevier in the author-pays charges model from 2011 to 2015. For experimentation, four sub-domains of computer science are selected including (a) artificial intelligence, (b) human–computer interaction, (c) computer vision and graphics, and (d) software engineering. The open-access and toll-based citation advantage is studied and analyzed at the micro level within the computer science domain by performing independent sample t-tests.FindingsThe results of the study highlight that open access articles have a higher citation advantage as compared to toll access articles across years and sub-domains. Further, an increase in open access articles has been observed from 2011 to 2015. The findings of the study show that the citation advantage of open access articles varies among different sub-domains of a subject. The study contributed to the body of knowledge by validating the positive movement toward open access articles in the field of computer science and its sub-domains. Further, this work added the success of the author-pays charges model in terms of citation advantage to the literature of open access.Originality/valueTo the best of the authors’ knowledge, this is the first study to examine the citation advantage of the author-pays charges model at a subject level (computer science) along with four sub-domains of computer science.

scholarly journals MANAGEMENT OF CHRONIC KIDNEY DISEASE BY AYURVEDA W.S.R. TO BASTI

2020 ◽  
Vol 8 (9) ◽  
pp. 4426-4430
Author(s):  
Bhuvnesh Sharma ◽  
Gyanendra Datta Shukla ◽  
Parul Sharma
Keyword(s):  
Quality Of Life ◽  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Body Fluid ◽  
Financial Burden ◽  
Vital Role ◽  
The Body ◽  
Gradual Loss ◽  
Urine Formation

Kidneys plays a vital role in homeostasis by maintaining the body fluid and removing the harmful toxins out of the body through urine formation. Chronic kidney disease is a type of kidney disease which is pro-gressive in nature and there is gradual loss of kidney function over a period of months or years and have complex and different etio-pathologies. With the growing number of cases and keeping in mind the availa-ble conventional line of treatment and its financial burden on patient, Ayurveda through its holistic line of management, either in the form of Shamana & Shodhana or in the form of dietary advices stand distinct and it seems to be effective and safe. And by including proper daily dietary rules and regimens in patients of Chronic kidney disease (CKD) it can be very effectively managed. Here Trinpanchmool, Punarnava, Gokshur used in Basti. Basti plays a vital role here in CKD, it helps in expelling out the uremic toxins which originates in gut thereby improving the quality of life and reducing the sign and symptoms of dis-ease.

scholarly journals The effect of public space indicators on the rural district’s life quality in Kuhdasht county, Iran

2021 ◽  
pp. 205-219
Author(s):  
Ahmad Roumiani ◽  
Taghi Ebrahimi Salari ◽  
Hamideh Mahmoodi ◽  
Mofid Shateri
Keyword(s):  
Public Space ◽  
Significant Relationship ◽  
Life Quality ◽  
Vital Role ◽  
The Body ◽  
Quality Enhancement ◽  
The Public ◽  
Quality Life ◽  
Significant Difference ◽  
Life Enhancement

This article evaluates nine rural districts in Kuhdasht county, Iran, with a population of 3535 between 2013–2016. We address the following two questions: First, what are the most important criteria and effective indicators in the rural population’s quality life enhancement? Second, is there any significant relationship between the public space indicators and quality life enhancement in the case study area? Six factors, including perceptual vision, buildings skeletons, culture and communities, activities, social interaction, and the environment from local peoples’ perspectives, explained 52.6 percent of the total variable variances. The Friedman test showed a significant difference among criteria of esthetics, semantic-perceptual, and activity-based functional at the alpha level of 0.01. The fitting growth regression model showed that the positive effect of the public space indicators on the rural population’s vitality and dynamism quality enhancement was about 0.723, indicating a significant relationship between them. It also stated a vital role of public space indicators in the rural population’s vitality and dynamism quality enhancement in the study area. The most important indicators were those of economic, social, and cultural dynamism and the body and space indicators.

scholarly journals Yogic Discipline in an individual human life

2021 ◽  
Vol 3 (4) ◽  
pp. 197-205
Author(s):  
Dharmalingam T.S ◽  
Balachandran P
Keyword(s):  
Human Life ◽  
Circulatory System ◽  
Vital Role ◽  
The Body ◽  
Self Control ◽  
Modern World ◽  
Breathing Exercise ◽  
Peace Of Mind ◽  
Self Confidence ◽  
Five Elements

In the modern world, the yoga plays a vital role in human life. To realise the truth and meaning of life, one has to practice yogic discipline in everyday living. The human body is made up of five elements such as akash, air, fire, water and earth. An air plays a very important role to survive by providing life energy. Everyday practice of pranayama would help in regulating respiratory system (Breathing exercise) as well as circulatory system. The physical exercises regulate the circulation of blood, heat, air in the body. The practice of asana would help in bringing flexibility in our muscular system so as to enhance the meditation process. The practice of meditation gives peace of mind and improves integirity. The practice of yoga will improve self-confidence, self-control, speaking truth, tolerance and social virtues. Each and every individual should practice yoga, asanas, meditation and do self-analysis exercises such as analysis of thoughts, moralisation of desires, nutralisation of anger and eradication of worries. This would help to bring hormoney between body and mind, habit and wisdom, self and society. Purpose and method and will and nature.

scholarly journals George French Angas and the Creation of Colonial Knowledge in New Zealand

2021 ◽  
Author(s):  
◽  
Catherine Falconer-Gray
Keyword(s):  
New Zealand ◽  
Vital Role ◽  
The Body ◽  
Middle Ground ◽  
Cultural Encounter ◽  
The Creation ◽  
The Aesthetic ◽  
Natural Historian ◽  
British Culture ◽  
New Zealanders

<p>In 1844, George French Angas, the English traveller, artist, natural historian and ethnographer spent four months travelling in New Zealand. He sought out and met many of the most influential Maori leaders of the time, sketching and recording his observations as he went. His stated intention was to provide a ‘more correct idea’ of New Zealand and the New Zealanders. In Australia and then Britain he held exhibitions of his work and in 1847 he published two works based on this time in New Zealand: a large volume of full-colour lithographs, The New Zealanders Illustrated and a travel narrative based on his journal, Savage Life and Scenes in Australia and New Zealand. These exhibitions and publications comprised the nineteenth century’s largest collection of works about Maori and Maori culture. This thesis is a study of the ‘more correct idea’ that Angas sought to provide: his creation of colonial knowledge about Maori. Angas is most commonly described in New Zealand as being an unremarkable artist but as providing a window onto New Zealand in the 1840s. This thesis opens the window wider by looking at Angas’s works as a record of a cultural encounter and the formation of a colonial identity. The works were shaped by numerous ideological and intellectual currents from Britain and the empire, including humanitarianism and the aesthetic of the picturesque. Ideas about gender and the body form a central part of the colonial knowledge created in Angas’s work. Particularly notable is what this thesis terms ‘sartorial colonisation’ – a process of colonisation through discourse and expectations around clothes. Angas also travelled and worked in a dynamic middle ground in New Zealand and Maori played a vital role in the creation of his works. Angas represented Maori in a sympathetic light in many ways. Ultimately however, he believed in the superiority of the British culture, to the detriment of creating colonial knowledge that placed Maori as equal partners in the recently signed Treaty of Waitangi. This thesis also examines the ways in which Angas’s body of work has been engaged with by the New Zealand public through to the present. As a study of the products of a British traveller who spent time in other parts of the empire as well as in New Zealand, this thesis contributes to histories of New Zealand, and British imperial and transcolonial history.</p>

scholarly journals Role of Education and Mentorship in Entrepreneurial Behavior: Mediating Role of Self-Efficacy

2021 ◽  
Vol 12 ◽  
Author(s):  
Binwu Hu ◽  
Qiang Zheng ◽  
Jie Wu ◽  
Zhibin Tang ◽  
Jianchun Zhu ◽  
...  
Keyword(s):  
Self Efficacy ◽  
Vital Role ◽  
The Body ◽  
Survey Study ◽  
Mediating Role ◽  
Farming Community ◽  
Body Of Knowledge ◽  
Behavioral Preferences ◽  
Structured Questionnaire

Farmers have been very precious for societies for ages. Their active experiments, valuable knowledge about their surroundings, environment, and crops’ requirements have been a vital part of society. However, the psychological perspectives have been a hole in the loop of farming. Hence, this study has investigated the antecedents of entrepreneurial behaviors of farmers with the mediating risk of their entrepreneurial self-efficacy (ESE). The population chosen for this study was the farming community of suburbs of China, and a sample size of 300 was selected for the data collection. This is a survey study, where a structured questionnaire was adapted on a five-point Likert scale. The data were collected from the farming community to know their psychological and behavioral preferences about their profession. This study has produced interesting results that education, training, and intrinsic motivation play a vital role in farmers’ ESE, affecting their entrepreneurial behaviors. This study will add to the body of knowledge and provide an eminent path for emerging entrepreneurs to find more mentorship opportunities to overcome the limitations in upcoming endeavors influencing education and training.

scholarly journals Significance of Diet and Behavior During Pandemic Situation According to Ayurveda

2021 ◽  
Author(s):  
Gaurav Sawarkar ◽  
Punam Sawarkar
Keyword(s):  
Health Care ◽  
Personalized Medicine ◽  
Vital Role ◽  
The Body ◽  
Unique Combination ◽  
Basic Principles ◽  
Main Culprit ◽  
Entire Cosmos ◽  
Prevention And Cure ◽  
And Behavior

Ayurveda is the oldest science of health care, explaining both the perspectives, i.e., prevention and cure of diseases. The fundamental principles of Ayurveda explore life’s philosophy, including the entire cosmos having five significant elements (Akash, Vayu, Agni, Jala, and Prithvi) establishing the Prakruti, i.e., a unique combination of physiological and psychological characteristics in a human being. In Ayurveda, Ahara (Diet), and Vihar (Exercise/Movements), fundamental pillars are thoroughly explained according to a specific Prakruti, which denotes personalized medicine in the present era. Diet is the essential factor that comprises the five significant elements with six rasas (Sweet, Sour, Saline, Pungent, Bitter, Astringent). Each Rasa has its specific nutritional properties helpful for the maintenance of health. Moreover, it also prevents diseases and plays a vital role in the restoration of health from disease conditions. The appropriate diet plan is essential in the pandemic situation because the digestive power (Agni) becomes hampered due to faulty lifestyle and unwholesome food habits that result in vitiation of three bio-humors (Vata, Pitta, Kapha) in the body. According to Ayurveda’s basic principles, weakened digestive power is the main culprit for forming various diseases. Therefore, it is highly imperative to select a suitable diet and behavioral regimes during pandemic situations.

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