scholarly journals Spontaneous pneumothorax as a complication of lung injury due to COVID-19

2021 ◽  
Vol 99 (3) ◽  
pp. 18-22
Author(s):  
A. V. Mikheev ◽  
E. V. Аftаevа ◽  
S. S. Kаzаkovа ◽  
Z. V. Zinovievа ◽  
I. N. Gаvrikovа
Keyword(s):  
Lung Injury ◽  
Spontaneous Pneumothorax ◽  
Laboratory Tests ◽  
Pleural Cavity ◽  
Lethal Outcome ◽  
Cardiovascular Failure ◽  
Radiation Data ◽  
Closed Drainage ◽  
The Moment ◽  
Surgery Department

The objective of the study: to study the course and clinical outcomes of spontaneous pneumothorax (SP) in patients with lung injury due to COVID-19.Subjects and methods. Clinical and radiation data of 11 patients (above 18 years old) with SP due to COVID-19 were retrospectively analyzed, they all were treated in the thoracic surgery department. COVID-19 was confirmed in all patients by laboratory tests. According to the chest computed tomography, the patients had signs typical of viral pneumonia and SP.Results. The surgical treatment of SP that included thoracocentesis on the pneumothorax side and closed drainage of the pleural cavity allowed resolving the pneumothorax and inflating the lung fully in 10/11 patients within 4 days on average (max = 7 days) from the moment when the surgery was done. The lethal outcome was in 1/11 (9.1%) patient which occurred 1 day after the diagnosis and successful drainage of the bilateral SP, the patient had symptoms of acute cardiovascular failure.

scholarly journals Modeling of Daily Global Solar Irradiation in Timisoara by Using a Fuzzy Approach

2018 ◽  
Vol 60 (1) ◽  
pp. 38-44 ◽  
Author(s):  
Remus Boata
Keyword(s):  
Simple Model ◽  
Solar Irradiation ◽  
Fuzzy Approach ◽  
Clearness Index ◽  
Model Accuracy ◽  
Radiation Data ◽  
Fuzzy Methods ◽  
Global Solar Irradiation ◽  
The Moment ◽  
Takagi Sugeno

AbstractThis paper proposes a new simple model to forecast daily global solar irradiation one day ahead using the Takagi-Sugeno fuzzy methods. The model is based on solar radiation data measured in Timisoara, Romania. The daily clearness index represents the direct variable used by the fuzzy algorithm. The model forecasts the clearness index at the moment of time t on basis of two previous values measured at time t-1 and t-2. An assessment of the model accuracy is performed.

scholarly journals On traumatic pneumothorax with primary gas injection

2021 ◽  
Vol 30 (9) ◽  
pp. 891-894
Author(s):  
V. K. Sokolova
Keyword(s):  
Spontaneous Pneumothorax ◽  
Pleural Cavity ◽  
Gas Injection ◽  
Lung Parenchyma ◽  
Pathological Process ◽  
Tuberculosis Patients ◽  
Gas Accumulation ◽  
The Press ◽  
Artificial Pneumothorax ◽  
Traumatic Pneumothorax

Over the last 10-15 years, treatment of tuberculosis patients with artificial pneumothorax has become widespread and there are many works devoted to collapse therapy in the press; details of the technique, efficiency of treatment, and complications are discussed. Spontaneous pneumothorax (SP) is one of the most dangerous complications of pneumothorax. Under p. p. we understand gas accumulation in pleural cavity in case of lung perforation, as the result of pathological process in the lung, more often of subpleural cavernous cavity breakthrough, caseous focus, or due to lung parenchyma needle trauma while applying pneumothorax.

scholarly journals Tumor budding as a prognostic criterion of colorectal cancer

Pathologia ◽  
2021 ◽  
Vol 18 (3) ◽  
pp. 346-351
Author(s):  
I. I. Yakovtsova ◽  
V. M. Cheverda ◽  
O. V. Dolhaia ◽  
A. S. Yakymenko ◽  
I. V. Ivakhno
Keyword(s):  
Colorectal Cancer ◽  
Malignant Tumors ◽  
Fatal Outcome ◽  
Tumor Budding ◽  
Lethal Outcome ◽  
Regional Lymph Nodes ◽  
Prognostic Features ◽  
Group I ◽  
Prognostic Criterion ◽  
The Moment

Colorectal cancer (CRC) is the second leading cause of mortality among cancers after malignant tumors of respiratory system. One of the most significant prognostic features of CRC is tumor budding (TB), which isn’t widely implemented in clinical practice. The aim of this research: to find the prognostic criteria of recurrence and lethal outcome of CRR IIA and IIIB stages (рТ3N0-2M0), the ratio of tumors with certain differentiation in groups of research was taken equal. Material and methods. The group I was formed from primary CRC without recurrences. The main relapse-free survival time was 5 years (62.5 ± 16.5 months). The ІІ group – primary CRC with recurrences; ІІА – with recurrences during 5 years from the moment when the tumor was removed, without fatal outcome; ІІВ – with recurrences and lethal outcome from genera­lization of tumor process during 5 years from the moment when the tumor was removed. The microslides of CRC were made by using the standard methods. Results. TB was identified in 46.66 % (28/60) of CRC рТ3N0-2M0. The direct relationship between tumor grade and presence of TB was found (Р < 0.05), but TB didn’t define differentiation of the CRC. There was a statistically significant relationship between TB and metastatic spreading of CRC to regional lymph nodes (Р < 0.001). Metastasis was associated with 3 stage of TB, absence of metastasis was typical for CRC without TB. The tendency was found in a larger number of cases of the CRC with TB 3 stage among recurring CRC compared with CRC without recurrence, mainly due to the ІІВ group of the research. Inverse correlation between TB stage and time of recurrence appearance was found (Р < 0.05). TB in central tumor sites was followed by presence and higher stage of TB in peripheral tumor sites (Р < 0.05), that can be taken into account during biopsies of CRC. Conclusions. TB is a prognostic criterion of metastasis and time of recurrence appearance for CRC рТ3N0-2M0, which is mostly typical for tumors in patients with recurrences and lethal outcome at the taken equal ratio of tumors by differen­tiation.

scholarly journals The assessment of severity of lung injury in sepsis

2004 ◽  
Vol 132 (11-12) ◽  
pp. 404-408
Author(s):  
Ljubica Arsenijevic ◽  
Nada Popovic ◽  
Zvezdana Kojic
Keyword(s):  
Acute Lung Injury ◽  
Lung Injury ◽  
Respiratory Distress Syndrome ◽  
Respiratory Distress ◽  
Distress Syndrome ◽  
Lung Injury Score ◽  
Pulmonary Dysfunction ◽  
Lethal Outcome ◽  
Injury Score ◽  
Respiratory Dysfunction

Adult respiratory distress syndrome (ARDS) is an acute and severe pulmonary dysfunction. It is clinically characterized by dyspnea and tachypnea, progressive hypoxemia (within 12-48 hours), reduction of pulmonary compliance and diffuse bilateral infiltrates seen on pulmonary radiogram. Etiological factors giving rise to development of the syndrome are numerous. The acute lung injury (AU) is defined as the inflammation syndrome and increased permeability, which is associated with radiological and physiological disorders. Lung injury score (LIS), which is composed of four components, is used for making a distinction between two separate but rather similar syndromes. The study was aimed at the assessment of the severity of the lung injury in patients who had suffered from sepsis of the gynecological origin and its influence on the outcome of the disease. The total of 43 female patients was analyzed. Twenty patients (46.51%) were diagnosed as having ARDS based on the lung injury score, while 23 patients (53.48%) were diagnosed with acute lung injury. In our series, lung injury score ranged from 0.7 to 3.3 in ARDS patients, and lethal outcome ensued in 11 (55%) cases in this group. As for the patients with the acute lung injury, the score values ranged from 0.3 to 1.3 and only one patient from this group died (4.34%). The obtained results indicate that high values of the lung injury score are suggestive of the severe respiratory dysfunction as well as that lethal outcome is dependent on LIS value.

SPONTANEOUS ALVEOLAR RUPTURE AT BIRTH

PEDIATRICS ◽  
1963 ◽  
Vol 32 (5) ◽  
pp. 816-824 ◽  
Author(s):  
Victor Chernick ◽  
Mary Ellen Avery
Keyword(s):  
Newborn Infant ◽  
Spontaneous Pneumothorax ◽  
Pleural Cavity ◽  
Fold Increase ◽  
Foreign Material ◽  
Newborn Period ◽  
Term Infants ◽  
Oxygen Breathing ◽  
Rate Of Absorption ◽  
Principles Of Treatment

Spontaneous pneumothorax in the newborn period was recognized in fifteen infants over a 6-year period. Seven of the 15 infants were symptomatic in the delivery room, which suggests that lung rupture occurred with the first few breaths. Three of the seven were meconium stained. The remaining eight infants were symptomatic within the first 24 hours. The unique features of the first breath of the newborn infant, namely, the serial opening of ventilatory units and high applied pressures, suggest that any foreign material in the airway would make rupture of opened units likely. Studies on the inflation of airless lungs demonstrate the opening phenomenon. Four of the 15 infants died, 2 from their pneumothoraces. This bad experience led us to examine principles of treatment of spontaneous pneumothorax with the recommendation that oxygen breathing in some term infants, and prompt aspiration in others would be useful. The majority, however, can be expected to resolve spontaneously. Measurements of the rate of absorption of air in the pleural cavity in the rabbit show a six-fold increase with 100% O2 breathing.

scholarly journals Novel imaging detailing the origins of a pneumothorax

Thorax ◽  
2017 ◽  
Vol 73 (1) ◽  
pp. 85-87 ◽  
Author(s):  
Kozo Nakanishi ◽  
Hidenori Goto ◽  
Tomokazu Ito ◽  
Yasuhito Nagata ◽  
Shinichi Hayashi ◽  
...  
Keyword(s):  
Clinical Study ◽  
Chest Tube ◽  
Spontaneous Pneumothorax ◽  
Pleural Cavity ◽  
Three Dimensional ◽  
Prospective Clinical Study ◽  
Air Leak ◽  
Air Stream ◽  
Cine Ct

This is a prospective clinical study aimed at introducing a method to visualise the location of an air leak and to identify the bulla responsible on three-dimensional (3-D) cine CT. In 10 patients with spontaneous pneumothorax, dynamic 320-detector row CT was performed with injection of 0.9% saline into the affected pleural cavity via a preplaced chest tube. In eight cases, 3-D cine CT thoracography revealed the location of the air leak and the bulla responsible (7 cases: air stream sign; 1 case: repeated collapse and expansion of a bulla with the patient's breathing).

scholarly journals THE MORPHOLOGY OF THE LUNGS AT THE EXPERIMENTAL ACUTE INJURY AND ITS PHARMACOCORRECTION

2020 ◽  
Vol 28 (2) ◽  
pp. 64-73
Author(s):  
Oleg A. Kulikov ◽  
Vladimir P. Balashov ◽  
Valentin P. Ageev ◽  
Elena V. Semenova ◽  
Vasilisa I. Shlyapkina ◽  
...  
Keyword(s):  
Acute Lung Injury ◽  
Lung Injury ◽  
Quantitative Assessment ◽  
Acute Injury ◽  
Control Group ◽  
Liposomal Form ◽  
Experimental Animals ◽  
Pharmacological Correction ◽  
The Moment ◽  
The Impact

The study of lung morphology under the influence of various environmental factors is of great interest for various areas of medicine and biology. The study of pathological changes in the respiratory part of the lung of rats with aspiration acute injury and the action of pharmacological correction was carried out. Acetone was used as a damaging agent, and HyperHAES was used as a means of pharmacological correction, containing 7.2% NaCl solution in combination with 6% hydroxyethyl starch, as well as a liposomal form of N-acetylcysteine, which was administered to experimental animals once intravenously after induction of acute lung injury. The control group of animals received antibiotic therapy. The staining of the slides was carried out using hematoxylin and eosin. A quantitative assessment of the histological signs of lung tissue damage was carried out. As a result of the study of preparations of the lungs, the degree of pulmonary edema was established, as well as the anti-edema effect of pharmacological corrections. On the 6th day of the experiment, the anti-edematous effect was retained only after the introduction of N-acetylcysteine. Histological examination of the lungs showed generalized destruction of the organ architectonics in response to the impact of a damaging factor and its reduction under the influence of pharmacological corrections. In the control group, the signs of acute lung injury were most extensive. One day after the administration of the HyperHAEC solution, there were no hemorrhages in the histological picture of the lungs. In a quantitative assessment of the histological signs of acute lung injury, it was shown that the maximum positive effect from the administration of HyperHAES develops 24 hours after application. N-acetylcysteine primarily led to a decrease in leukocyte infiltration and prevented the development of a suppurative process. The lung-protective effect of N-acetylcysteine was realized in 24 hours from the moment of administration and persisted until the 6th day of the experiment. The use of pharmacological correction agents in acute lung injury was reflected in the picture of the lethality of the experimental animals. When HyperHAES was applied, 37.5% of animals died by day 6, in the group with N-acetylcysteine - 28.6%, while in the control group all animals died.

scholarly journals Kraujo krešumo sistemos pokyčiai sergant paveldimąja plaučių emfizema

2005 ◽  
Vol 3 (1) ◽  
pp. 0-0
Author(s):  
Vytis Bajoriūnas ◽  
Romaldas Rubikas ◽  
Paulius Gradauskas ◽  
Diana Samiatina ◽  
Algirdas Vilčinskas ◽  
...  
Keyword(s):  
Pulmonary Emphysema ◽  
Spontaneous Pneumothorax ◽  
Blood Clotting ◽  
Pleural Cavity ◽  
University Hospital ◽  
The Family ◽  
Antitrypsin Deficiency ◽  
Alpha 1 Antitrypsin Deficiency ◽  
Alpha 1 Antitrypsin ◽  
Medical University

Vytis Bajoriūnas, Romaldas Rubikas, Paulius Gradauskas, Diana Samiatina, Algirdas Vilčinskas, Leonas JasulaitisKauno medicinos universitetoTorakalinės chirurgijos klinika,Eivenių g. 2, LT-50009 KaunasEl paštas: [email protected], [email protected] Įvadas Pateikiami penkių gydytų pacientų ligos istorijų duomenys, aprašoma kraujo krešumo sistemos patologija sergant paveldima plaučių emfizema. Ligoniai ir metodai 2000–2003 metais Torakalinės chirurgijos klinikoje gydyti penki vienos giminės nariai, sirgę spontaninio pneumotorakso komplikuota plaučių emfizema. Įgimta plaučių emfizema šeimoje sirgo ir šiuo metu serga 12 žmonių. Visi ligoniai buvo operuoti. Atliktos torakotomijos, rezekuota pažeista plaučio dalis, atlikta dalinė arba visiškoji pleurektomija, drenuota pleuros ertmė. Rezultatai Pooperaciniu laikotarpiu visiems ligoniams padidėjo kraujavimas į pleuros ertmę. Netekto kraujo tūris buvo papildomas hemotransfuzija, šviežiai šaldytos plazmos infuzijomis. Dėl kraujavimo į pleuros ertmę ar susidariusio hemotorakso buvo atliktos trys retorakotomijos. Pakartotinių operacijų metu buvo rastas įvairaus dydžio hemotoraksas (600–1100 ml), difuzinis kraujavimas iš krūtinės sienos be aiškaus vieno kraujavimo židinio. Visi pacientai pasveiko. Išvada Turimi duomenys yra būdingi įgimtam alfa-1 antitripsino sintezės defektui. Reikšminiai žodžiai: plaučių emfizema, spontaninis pneumotoraksas, pooperacinės komplikacijos, antitrombinas III Malfunction of blood clotting associated with hereditary pulmonary emphysema Vytis Bajoriūnas, Romaldas Rubikas, Paulius Gradauskas, Diana Samiatina, Algirdas Vilčinskas, Leonas JasulaitisClinic of Thoracic Surgery,Kaunas University of Medicine,Eivenių str. 2, LT-50009 Kaunas, LithuaniaE-mail: [email protected], [email protected] Background / objective There were five members of one family suffering from pulmonary emphysema complicated with spontaneous pneumothorax, treated at Kaunas Medical University Hospital since 2000 till 2003. The data from the case histories of all the patients are presented and the possible reasons for blood clotting dysfunction are discussed. Patients and methods Twelve members of the family have been or still are suffering from congenital pulmonary emphysema. Five members of the family were operated on. The surgey involved thoracotomy, resection of the damaged section of a lung, partial or total pleurectomy, pleural cavity drainage. Results All the patients underwent surgery, and in all cases the postoperative intrapleural bleeding was uncommonly intensive. In three cases rethoracotomies were performed. All patients survived. Conclusion The presented data characterise congenital alpha-1-antitrypsin deficiency. Keywords: pulmonary emphysema, spontaneous pneumothorax, post-operative complications, antithrombin

scholarly journals Profil hasil pemeriksaan foto toraks pada pasien pneumotoraks di Bagian / SMF Radiologi FK Unsrat RSUP Prof. Dr. R. D. Kandou Manado periode Januari 2015 – Agustus 2016

e-CliniC ◽  
2016 ◽  
Vol 4 (2) ◽  
Author(s):  
Windy D.P. Masengi ◽  
Elvie Loho ◽  
Vonny Tubagus
Keyword(s):  
Medical Records ◽  
Spontaneous Pneumothorax ◽  
Pleural Cavity ◽  
Secondary Data ◽  
Descriptive Study ◽  
Age Group ◽  
X Ray ◽  
Secondary Spontaneous Pneumothorax ◽  
Chest X Ray ◽  
The Right

Abstract: Radiology examination especially chest x-ray can enforce various kinds of pulmonary diseases inter alia pneumothorax. Pneumothorax is defined as the presence of air in the pleural cavity. The causes of pneumothorax are very diverse ranging from idiopathic, infection, trauma, and iatrogenic. This study was aimed to obtain the profile of chest x-ray in patients with pneumothorax. This was a retrospective descriptive study by using secondary data from the medical records at the Department of Radiology Prof. Dr. R. D. Kandou Hospital Manado from January 2015 to August 2016. Samples were the medical records of patients that were radiologically diagnosed as pneumothorax. There were 41 patients that were diagnosed radiologically as pneumothorax. The majority of cases were male (90.2%), age group >50 years (36.6%), location of lesion in the right hemithorax (53.7%), and secondary spontaneous pneumothorax as the etiology (43,9 %). Conclusion: In this study, pneumothorax was more common among males, age group of ≥50 years, and secondary spontaneous pneumothorax as the etiology of pneumothorax.Keywords: pneumothorax, radiology, chest x-ray Abstrak: Pemeriksaan radiologi khususnya foto toraks dapat menegakkan berbagai macam diagnosis penyakit paru, salah satunya ialah pneumotoraks. Pneumotoraks adalah terdapatnya udara bebas didalam rongga pleura dengan penyebab yang sangat beragam mulai dari idiopatik, infeksi, trauma, maupun iatrogenik. Penelitian ini bertujuan untuk mengetahui profil hasil pemeriksaan foto toraks pada pasien pneumotoraks. Jenis penelitian ialah deskriptif retrospektif dengan pengambilan data di Bagian Radiologi RSUP Prof. Dr. R. D. Kandou Manado pada bulan Januari 2015 sampai dengan Agustus 2016. Sampel yaitu data rekam medik pasien yang didiagnosis pneumotoraks secara radiologis sebanyak 41 pasien. Yang tersering ditemukan ialah pasien laki-laki sebanyak 37 orang (90,2%), kelompok usia >50 tahun sebanyak 15 orang (36,6%), lokasi lesi hemitoraks deksra sebanyak 22 kasus (53,7%), serta etiologi pneumotoraks spontan sekunder sebanyak 18 kasus (43,9%). Simpulan: Pada penelitian ini didapatkan pneumotoraks paling banyak pada laki-laki, kelompok usia ≥50 tahun, dengan pneumotoraks spontan sekunder sebagai etiologi tersering. Kata kunci: pneumotoraks, radiologi, foto toraks

scholarly journals Experience of treatment of endometriosisrelated pneumothorax

2017 ◽  
Vol 176 (3) ◽  
pp. 56-60
Author(s):  
V. G. Pishchik ◽  
A. D. Obornev ◽  
M. A. Atyukov ◽  
A. S. Petrov ◽  
A. I. Kovalenko
Keyword(s):  
Surgical Treatment ◽  
Hormone Therapy ◽  
Spontaneous Pneumothorax ◽  
Pleural Cavity ◽  
Reproductive Age ◽  
Control Group ◽  
Visual Examination ◽  
Women Of Reproductive Age ◽  
Course Of Disease

OBJECTIVE. The article analyzed the experience of treatment of endometriosis-related pneumothorax (ERP). MATERIAL AND METHODS. The diagnosis of ERP was detected in 30 women at the period from 2004 to 2015. A control group consisted of 149 women. RESULTS. Statistically significant differences associated with presence of ERP were the elder age, right-side localization and recurrence course of disease. Diaphragmatic fenestrations and endometriotic ectopy and their combinations were specific findings in ERP-group. This group of patients characterized by frequent recurrences and higher rate of complications. The most effective method of treatment of ERP was diaphragm resection with pleurectomy and hormone therapy from 3 to 6 months after surgery. CONCLUSIONS. Endometriosis-related pneumothorax could cause up to 34 % cases of spontaneous pneumothorax in women of reproductive age. Diaphragmatic fenestrations and endometriotic lesions were specific signs of EAP. Direct visual examination of the pleural cavity was inevitable for reliable diagnostics of the disease. Surgical treatment of ERP was determined by higher rates of complication and recurrence. Postoperative hormone therapy could significantly improve the results of surgical treatment of ERP.

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