Effect of Low Dietary Glycemic Index on Blood Lipids Profile among Obese Postpartum Women

AbstractObjective: Postpartum obesity leads to long-term maternal obesity and promotes drastic health complications. Low glycemic index diet is suggested to have a beneficial impact on blood lipid levels. Therefore, we conducted a study to explore the effect of low glycemic diet on blood lipid profile in obese postpartum women.Methods: In a randomised controlled trial, 38 obese postpartum women in intervention and 36 obese post-partum women in control group were analysed. Subjects in the intervention group were assigned low glycemic index diet and to follow this protocol for 12 weeks and the control group was advised to continue their routine diet.Results: Low glycemic diet had a positive impact on low density lipoprotein (LDL), triglyceride and highdensity lipoprotein (HDL) concentration (p < 0.05). A strong positive correlation was observed between the glycemic index and LDL (mg/dl), (r = 0.57; p = 0.02) and between glycemic index and triglyceride (mg/dl), (r = 0.51; p = 0.01) in control and intervention group. A negative correlation was identified between glycemic index and HDL (mg/dl), (r = -0.45; p = 0.01).Conclusion: Study concluded that low glycemic index diet reduced low density lipoprotein and triglyceride level and increased HDL level in blood; further more a significant association was found between glycemic index and blood lipids profile.

Download Full-text

Prevalence and associations of behavioural risk factors with blood lipids profile in Lebanese adults: findings from WHO STEPwise NCD cross-sectional survey

BMJ Open ◽

10.1136/bmjopen-2018-026148 ◽

2019 ◽

Vol 9 (8) ◽

pp. e026148

Author(s):

Megali Mansour ◽

Hani Tamim ◽

Lara Nasreddine ◽

Christelle El Khoury ◽

Nahla Hwalla ◽

...

Keyword(s):

Physical Activity ◽

Cigarette Smoking ◽

Blood Lipids ◽

Low Density Lipoprotein ◽

Saturated Fat ◽

Density Lipoprotein ◽

Fat Intake ◽

Cross Sectional ◽

Lipids Profile ◽

Saturated Fat Intake

ObjectiveTo examine associations of behavioural risk factors, namely cigarette smoking, physical activity, dietary intakes and alcohol consumption, with blood lipids profile.Design and participantsData drawn from a cross-sectional study involving participants aged 18 years and over (n=363) from the nationwide WHO STEPwise Nutrition and Non-communicable Disease Risk Factor survey in Lebanon.MeasuresDemographic characteristics, behaviours and medical history were obtained from participants by questionnaire. Dietary assessment was performed using a 61-item Culture-Specific Food Frequency Questionnaire that measured food intake over the past year. Lipid levels were measured by the analysis of fasting blood samples (serum total cholesterol (TC), triglycerides (TG), very low-density lipoprotein (VLDL), low-density lipoprotein cholesterol (LDL-C) and high-density lipoprotein cholesterol (HDL-C)).ResultsCurrent cigarette smoking, alcohol consumption and low physical activity were prevalent among 33.3%, 39.7% and 41.6% of the sample, respectively. The contributions of fat and saturated fat to daily energy intake were high, estimated at 36.5% and 11.4%, respectively. Abnormal levels of TC, TG, VLDL, LDL-C and HDL-C were observed for 55.4%, 31.4%, 29.2%, 47.5% and 21.8% of participants, respectively. Adjusting for potential confounders, cigarette smoking was positively associated with higher odds of TG and VLDL (OR=4.27; 95% CI 1.69 to 10.77; and 3.26; 95% CI 1.33 to 8.03, respectively) with a significant dose–response relationship (p value for trend=0.010 and 0.030, respectively). Alcohol drinking and high saturated fat intake (≥10% energy intake) were associated with higher odds of LDL-C (OR=1.68; 95% CI 1.01 to 2.82 and OR= 1.73; 95% CI 1.02 to 2.93). Physical activity did not associate significantly with any blood lipid parameter.ConclusionThe demonstrated positive associations between smoking, alcohol drinking and high saturated fat intake with adverse lipoprotein levels lay further evidence for clinical practitioners, public health professionals and dietitians in the development of preventive strategies among subjects with a high risk of cardiovascular diseases in Lebanon and other neighbouring countries with similar epidemiological profile.

Download Full-text

Plasma lipid profile of mice fed diet supplemented with broiler fat

Bangladesh Journal of Animal Science ◽

10.3329/bjas.v43i1.19380 ◽

2014 ◽

Vol 43 (1) ◽

pp. 21-24 ◽

Cited By ~ 2

Author(s):

GB Das ◽

ME Hossain ◽

MA Akbar

Keyword(s):

Lipid Profile ◽

Palm Oil ◽

Low Density Lipoprotein ◽

Plasma Lipid ◽

Density Lipoprotein ◽

Dietary Treatment ◽

Blood Lipid ◽

Blood Cholesterol ◽

Control Group ◽

Blood Lipid Profile

This study was conducted with 180 female Swiss albino mice to examine the effects of supplementing broiler fat in the diets of mice on blood lipid profile. Twenty one days old mice were collected from ICDDRB, Mohakhali, Dhaka. They were randomly distributed in four groups having three replications each. Each replicate group had 15 mice. Results revealed that supplementation of broiler fat in mice diet significantly changed (p<0.05) triglyceride (TG) and low density lipoprotein (LDL) among groups. The control group (T0) had the highest level of cholesterol and LDL. Cholesterol, TG and LDL markedly increased (p<0.05) in all dietary treatment groups, while high density lipoprotein (HDL) significantly (p<0.01) decreased after supplementation of experimental diets. It was concluded that all the dietary treatments in general increased blood cholesterol, TG and LDL in mice fed broiler fat with different oil supplements. However, the soybean and palm oil group was comparatively better than other groups in respect of cholesterol, HDL and LDL at the blood lipid profile of mice. Therefore, it can be concluded that consumption of broiler fat with soybean and palm oil could be less harmful for mice.DOI: http://dx.doi.org/10.3329/bjas.v43i1.19380 Bang. J. Anim. Sci. 2014. 43 (1): 21-24

Download Full-text

Optimal cut-off points after a daily meal corresponding to fasting goal levels of LDL-C and non-HDL-C in Chinese patients with coronary heart disease

10.21203/rs.2.20892/v1 ◽

2020 ◽

Author(s):

Li-Ling Guo ◽

Yan-qiao Chen ◽

Qiu-zhen Lin ◽

Feng Tian ◽

Qun-Yan Xiang ◽

...

Keyword(s):

Coronary Heart Disease ◽

Heart Disease ◽

Blood Lipids ◽

Low Density Lipoprotein ◽

Density Lipoprotein ◽

Blood Lipid ◽

Lipoprotein Cholesterol ◽

Chinese Patients ◽

C Statistic ◽

Blood Lipid Levels

Abstract Background: Although the detection of non-fasting blood lipids has been recommended in patients with coronary heart disease (CHD), the non-fasting cut-off points corresponding to the fasting goals of LDL-C < 1.8 mmol/Land non-HDL-C < 2.6 mmol/L, respectively, have not been explored. Methods: This study enrolled 397 inpatients with CHD. One hundred and ninety-seven patients took statins for < 1 month (m) or did not take any statin before admission (i.e. CHD1 group), while 204 patients took statins for ≥ 1 m before admission (i.e. CHD2 group). Blood lipid levels were measured at 0 h, 2 h, and 4 h after a daily breakfast. Results: Non-fasting low-density lipoprotein cholesterol (LDL-C) and non-high-density lipoprotein cholesterol (non-HDL-C) levels significantly decreased after a daily meal ( P < 0.05). Both fasting and non-fasting LDL-C or non-HDL-C levels were significantly lower in the CHD2 group. The percent attainment of LDL-C < 1.8 mmol/L at 2 h or 4 h after a daily breakfast was significantly higher than that of its fasting point ( P < 0.05), whereas that of non-HDL-C < 2.6 mmol/L was significantly higher only at 4 h ( P < 0.05). Analysis of c-statistic showed that non-fasting cut-off points for LDL-C and non-HDL-C were 1.5 mmol/L and 2.4 mmol/L, corresponding to their fasting goal levels of 1.8 mmol/L and 2.6 mmol/L, respectively. When postprandial LDL-C and non-HDL-C goal attainments were re-evaluated by non-fasting cut-off points, there were no significant differences in percent attainment between fasting and non-fasting states. Conclusions: Determination ofnon-fasting cut-off points is important to evaluate the efficacy of cholesterol-lowering therapy if blood lipids are detected after a daily meal.

Download Full-text

JUS PEPAYA (CARICA PAPAYA L) DAPAT MENURUNKAN KADAR LDL DAN KOLESTEROL TOTAL PADA USIA 40-70 TAHUN

Jurnal Kesehatan Kusuma Husada ◽

10.34035/jk.v9i2.274 ◽

2018 ◽

pp. 153-161

Author(s):

Junendri Ardian ◽

Ari Natalia Probandari ◽

K Kusnandar

Keyword(s):

High Density Lipoprotein ◽

Carica Papaya ◽

Low Density Lipoprotein ◽

Intervention Group ◽

Density Lipoprotein ◽

High Density ◽

Control Group ◽

Low Density ◽

Post Test ◽

Research Show

ABSTRAK Hiperkolesterolemia merupakan suatu kondisi dimana kolesterol dalam darah meningkat melebihi ambang normal yang ditandai dengan meningkatnya kadar kolesterol total terutama Low Density Lipoprotein (LDL) dan diikuti dengan penurunan kadar High Density Lipoprotein (HDL) darah, Tujuan penelitian adalah menganalisis pengaruh pemberian asupan jus pepaya terhadap kadar LDL dan kolesterol total pada ibu rumah tangga usia 40-70 tahun yang menderita hiperkolesterolemia. Metode: Jenis penelitian ini merupakan penelitian true eksperimental dengan desain penelitian pre and post test with control group. Total subjek sebanyak 20 orang yang dibagi kedalam dua kelompok, yaitu Intervensi Jus pepaya dan kelompok kontrol. Hasil penelitian menunjukkan bahwa kadar kolesterol total pada kelompok jus pepaya mengalami penurunan yang bermakna (p<0,05). Sedangkan pada kelompok kontrol tidak bermakna (p>0,05). Kadar LDL pada kelompok jus pepaya mengalami penurunan yang bermakna (p<0,05). Sedangkan pada kelompok kontrol tidak bermakna (p>0,05). Kesimpulan jus pepaya (carica papaya l) dapat menurunkan kadar LDL (Low Density Lipoprotein) dan kolesterol total. Kata kunci: jus pepaya, kolesterol total, LDL. ABSTRACT Hypercholesterolemia is a conditions where cholesterol in the bloods increased beyond the normal standard, its showed with cholesterol total level’s was increased especially Low Density Lipoprotein (LDL) and followed by the decreasing of High Density Lipoprotein (HDL) in blood, The purpose of this research is analyzing the influence’s of papaya juice intake for LDL’s levels and cholestrol’s total at the age of 40 – 70 years old for housewives with hypercholesterolemia. The method this research is true experimental researchs with pre and post test control group designs. The subject in this research are 20 people and separated into two groups, the first group is papaya juice’s intervention group, and the second is control group. The result of this research show that papaya juice’s has significant result for decreasing cholesterol’s total with p value’s < 0,05 , while the control group has no significant result because its p value’s >0,05. The result for LDL’s levels show that papaya juice’s has significant result too for decreasing LDL’s levels with p value’s < 0,05, while the control group has no significant result because its p value’s >0,05. The conclusion in this research is papaya juice (carica papaya l) can decreased ldl’s levels and cholesterol’s total. Keywords: cholesterol’s total, LDL, papaya juice.

Download Full-text

Comparison Between Fasting and Non-Fasting Cut-Off Values of Triglyceride in Diagnosing High Triglyceride in Chinese Hypertensive Outpatients

10.21203/rs.3.rs-961584/v1 ◽

2021 ◽

Author(s):

Yingying Xie ◽

Peiliu Qu ◽

Tie Wen ◽

Ling Liu ◽

Xiao Du ◽

...

Keyword(s):

Blood Lipids ◽

Statistical Significance ◽

Low Density Lipoprotein ◽

Venous Blood ◽

Density Lipoprotein ◽

Direct Methods ◽

Blood Lipid ◽

Serum Levels ◽

Lipoprotein Cholesterol ◽

Fasting State

Abstract Background: Hypertension (HBP) often occurs together with hypertriglyceridemia that indicates elevated triglyceride (TG) and remnant cholesterol (RC) levels. Non-fasting (i.e. postprandial) blood lipid test after a daily meal has been recommended by the European Atherosclerosis Society (EAS). However, little is known about the difference between fasting and non-fasting cut-off values in assessing high TG (HTG) and high RC (HRC) in HBP outpatients.Methods: Two hundred and twenty-five Chinese outpatients with HBP were enrolled in this study. According to the time of blood lipid test, they were divided into two groups, i.e. the fasting group (n=119) and the non-fasting group (n=139). Non-fasting levels of blood lipids at 2 h after a daily breakfast were also tested in 33 patients among the fasting group. Venous blood samples were collected. Serum levels of blood lipids were measured by the enzymatic and direct methods on a HITACHI 7170A analyzer or estimated via related formulas. Results: The non-fasting group had significantly higher levels of TG and RC while lower levels of total cholesterol, low-density lipoprotein cholesterol and non-high-density lipoprotein cholesterol than the fasting group (P＜0.05). According to TG and RC cut-off values of the EAS, the percentages of HTG and HRC in the non-fasting group were 67.6% and 65.6%, respectively, while those in the fasting group were 57.1% and 52.9%, respectively. However, the percentages of HTG in the fasting state and at 2 h after a daily breakfast in 33 outpatients did not reach statistical significance (57.6% v.s. 51.5%). So did the fasting and at 2 h non-fasting percentages of HRC in them.Conclusion: Non-fasting blood lipid test could find more HBP outpatients with HTG in Chinese outpatients with HBP. However, the percentage of HTG at 2h after a daily breakfast seemed to be close to that in the fasting state.

Download Full-text

Vitamin D Supplementation is Associated with Increased Glutathione Peroxidase-1 Levels in Arab Adults with Prediabetes

Antioxidants ◽

10.3390/antiox9020118 ◽

2020 ◽

Vol 9 (2) ◽

pp. 118 ◽

Cited By ~ 2

Author(s):

Mohammed Ghouse Ahmed Ansari ◽

Shaun Sabico ◽

Mario Clerici ◽

Malak Nawaz Khan Khattak ◽

Kaiser Wani ◽

...

Keyword(s):

Vitamin D ◽

Glutathione Peroxidase ◽

Low Density Lipoprotein ◽

Intervention Group ◽

Density Lipoprotein ◽

Vitamin D Supplementation ◽

Control Group ◽

Post Intervention ◽

Glutathione Peroxidase 1 ◽

Reactive Protein

Vitamin D supplementation may be used to lower oxidative stress. This interventional study aimed to investigate the effects of vitamin D supplementation on glutathione peroxidase 1 (GPx1) levels and other parameters in Arab adults with prediabetes. A total of 203 Saudi adults with prediabetes and vitamin D deficiency [intervention group, N = 146 (53 males and 93 females); control group, N = 57 (25 males and 32 females)] were included in this non-randomized, six-month intervention study. The intervention group received 50,000 international units (IU) cholecalciferol tablets once a week for two months, then twice a month for the next two months, followed by 1000 IU daily for the last two months. The control group received no supplementation. Serum 25(OH)D, lipid profile, glucose, C-reactive protein (CRP) and GPx1 were measured at baseline and after six months. Post-intervention, GPx1 concentrations increased significantly in the intervention group [17.3 (11.5–59.0) vs 26.7 (11.4–59.9) p < 0.01] while no changes were observed in the control group (p = 0.15). This significant increase in 25(OH)D and GPx1 levels persisted after adjusting for age and BMI. Stratification according to sex revealed that this favourable increase in GPx1 was true only for males (p = 0.002). In all groups, baseline GPx1 was inversely correlated with low density lipoprotein (LDL)-cholesterol (r = −0.26, p < 0.01) and body mass index (BMI) (r = −0.20, p < 0.05), while positively correlated with age (r = 0.18, p < 0.05) and systolic blood pressure (r = 0.19, p < 0.05). In conclusion, vitamin D supplementation favourably enhanced GPx1 levels in adult Arabs with prediabetes, particularly in males.

Download Full-text

Elevated free testosterone levels and reduced very low-density lipoprotein levels in men with lifelong premature ejaculation: a preliminary study

Journal of International Medical Research ◽

10.1177/03000605211002681 ◽

2021 ◽

Vol 49 (4) ◽

pp. 030006052110026

Author(s):

Jun Zhao ◽

Yubo Ma ◽

Xiaoqiang Zhai ◽

Hecheng Li ◽

Ziming Wang ◽

...

Keyword(s):

Premature Ejaculation ◽

Low Density Lipoprotein ◽

Density Lipoprotein ◽

Blood Lipid ◽

Free Testosterone ◽

Control Group ◽

Very Low Density Lipoprotein ◽

Low Density ◽

Testosterone Levels ◽

Lifelong Premature Ejaculation

Objective To investigate sex hormone and blood lipid levels in patients with lifelong premature ejaculation (LPE) in China. Methods Sex hormone and blood lipid levels were measured in 156 patients with LPE and 76 healthy controls. The Premature Ejaculation Diagnostic Tool (PEDT) and Chinese Index of Sexual Function for Premature Ejaculation-5 Questionnaires (CIPE-5) were applied to diagnose and grade LPE. Results PEDT and CIPE-5 scores were significantly altered in the LPE group compared with the control group. Free testosterone levels were significantly higher in the LPE group than in the control group. Free testosterone levels were also significantly higher in the mild, moderate, and severe LPE subgroups than in the control group. Total testosterone and prolactin levels tended to be lower in the control group than in the LPE group. Very low-density lipoprotein levels were significantly lower in the LPE group and LPE subgroups than in the control group. Triglyceride levels were highest in controls and decreased with progression of LPE. Conclusions Patients with LPE have higher free testosterone levels and lower very low-density lipoprotein levels than controls. These findings indicate that these factors might be indices for LPE. However, the reasons for these phenomena need to be further investigated.

Download Full-text

Randomized Control Trial Study On The Effect Of Wet Cupping On Lipid Profile

IIUM Medical Journal Malaysia ◽

10.31436/imjm.v16i2.319 ◽

2020 ◽

Vol 16 (2) ◽

Author(s):

Suhaily MH ◽

Ismail AA ◽

Najib MY

Keyword(s):

Lipid Profile ◽

Serum Lipid ◽

Controlled Trial ◽

Low Density Lipoprotein ◽

Venous Blood ◽

Intervention Group ◽

Density Lipoprotein ◽

Lipoprotein Cholesterol ◽

Control Group ◽

The Third

Introduction: Dyslipidaemia is one of the risk factors contributing to the pathogenesis of cardiovascular diseases (CVDs). This study was conducted to investigate the effect of wet cupping on lipid profile. Methods: This randomized controlled trial was conducted in 2012 at the School of Medical Sciences, Universiti Sains Malaysia, Malaysia. Sixty-two healthy volunteers ranging from 30 to 60 years old were randomized into control and intervention groups. Subjects in the intervention group were assigned to two sessions of wet cupping at the beginning of the study and at the third month; individuals in the control group did not undergo any cupping procedure. Venous blood sample was collected for serum lipid profile: Total Cholesterol (TC), High Density Lipoprotein Cholesterol (HDL-C), Low Density Lipoprotein Cholesterol (LDL-C), and triglycerides; measured at baseline, first, third and fourth month. Results: Subjects in the cupping group had significant improvements from baseline to third and fourth month for TC (MD=-0.56, P=0.004), HDL-C (MD=-0.22, P<0.001) and LDL-C (MD=0.58, P=0.001). There was also a significant reduction from baseline to one month for triglycerides (MD=0.38, P<0.001). Subjects in the cupping group had significantly better values in HDL-C and LDL-C as compared with the control group at the third and fourth month. Significantly lower levels of TC and triglycerides in the cupping group of the fourth month. In the control group, there were no significant changes in any serum lipid profiles. Conclusion: After two sessions of wet cupping, TC, HDL-C, LDL-C and triglycerides were significantly improved by 8.2%, 13.7%, 16.4% and 20.8% respectively.

Download Full-text

Blood Lipid and Physiological Responses to Endurance Training in Adolescents

Pediatric Exercise Science ◽

10.1123/pes.7.2.192 ◽

1995 ◽

Vol 7 (2) ◽

pp. 192-202 ◽

Cited By ~ 19

Author(s):

Daniel L. Blessing ◽

Robert E. Keith ◽

Henry N. Williford ◽

Marjean E. Blessing ◽

Jeff A. Barksdale

Keyword(s):

Endurance Training ◽

Blood Lipids ◽

Density Lipoprotein ◽

Blood Lipid ◽

Control Group ◽

Physical Conditioning ◽

Working Capacity ◽

Physical Measurements ◽

Males And Females ◽

Lipids And Lipoproteins

The purpose of this study was to determine the effects of an endurance training program on blood lipids and lipoproteins in adolescents. Fifteen males and 10 females, ages 13 to 18 years, underwent pretest evaluations, including physical measurements, nutritional intake, physical working capacity (PWC), and fasting serum lipid and lipoprotein levels. Physical conditioning consisted of a 16-week progressive endurance training (ET) program 40 min·day1 three times per week. Twenty-five males and females matched for age, sex, and race served as controls. Following the conditioning program, the ET group had a significant increase (p < .05) in PWC and a significant decrease (p < .05) in sum of skinfolds and resting heart rate. A significant decrease (p < .05) was also noted for total cholesterol (TC) and the ratio of TC to high density lipoprotein cholesterol (HDL-C) with a significant increase (p < .05) in HDL-C. No differences were found for the control group. The results suggest that 16 weeks of endurance training favorably improves blood lipid profiles in adolescents.

Download Full-text

Training intensity, blood lipids, and apolipoproteins in men with high cholesterol

Journal of Applied Physiology ◽

10.1152/jappl.1997.82.1.270 ◽

1997 ◽

Vol 82 (1) ◽

pp. 270-277 ◽

Cited By ~ 39

Author(s):

Stephen F. Crouse ◽

Barbara C. O’Brien ◽

Peter W. Grandjean ◽

Robert C. Lowe ◽

J. James Rohack ◽

...

Keyword(s):

Repeated Measures ◽

Blood Lipids ◽

Low Density Lipoprotein ◽

Density Lipoprotein ◽

Hdl Cholesterol ◽

Blood Lipid ◽

Cycle Ergometer ◽

Training Intensity ◽

High Cholesterol ◽

Apo B

Crouse, Stephen F., Barbara C. O’Brien, Peter W. Grandjean, Robert C. Lowe, J. James Rohack, John S. Green, and Homer Tolson.Training intensity, blood lipids, and apolipoproteins in men with high cholesterol. J. Appl. Physiol.82(1): 270–277, 1997.—Twenty-six hypercholesterolemic men (mean cholesterol, 258 mg/dl; age, 47 yr; weight, 81.9 kg) completed 24 wk of cycle ergometer training (3 days/wk, 350 kcal/session) at either high ( n = 12) or moderate ( n = 14) intensity (80 and 50% maximal O2uptake, respectively, randomly assigned) to test the influence of training intensity on blood lipid and apolipoprotein (apo) concentrations. All physiological, lipid, and apo measurements were completed at 0, 8, 16, and 24 wk. Lipid data were analyzed via two × four repeated-measures analysis of variance (∝ = 0.0031). Training produced a significant decrease in body weight and increase in maximal O2uptake. No interactions between intensity and weeks of training were noted for any lipid or apo variable, and no between-group differences were significant before or throughout training. Therefore, intensity did not affect the training response. Regardless of intensity, apo AI and apo B fell 9 and 13%, respectively, by week 16 and remained lower through week 24( P < 0.0003). Total cholesterol fell transiently (−5.5%) by week 16( P < 0.0021) but returned to initial levels by week 24. Triglyceride, low-density-lipoprotein cholesterol, and high-density-lipoprotein (HDL) cholesterol did not change with training. In contrast, HDL2cholesterol rose 79% above initial levels by week 8 and 82% above initial levels by week 24( P < 0.0018); HDL3cholesterol fell 8 and 13% over the same training intervals ( P< 0.0026). These data show that changes in blood lipid and apo concentrations that accompany training in hypercholesterolemic men are not influenced by exercise intensity when caloric expenditure is held constant.

Download Full-text