Global Comprehensive Outlook of Hantavirus Contagion on Humans: A Review

2022 ◽  
Vol 22 ◽  
Author(s):  
Sumel Ashique ◽  
Navjot K Sandhu ◽  
Supratim Das ◽  
Sk. Niyamul Haque ◽  
Kartick Koley
Keyword(s):  
Signs And Symptoms ◽  
Hemorrhagic Fever ◽  
Western United States ◽  
Human Beings ◽  
Rodent Host ◽  
Andes Virus ◽  
Etiologic Agents ◽  
Virus Serotype ◽  
The Family ◽  
Negative Sense

Abstract: Hantaviruses are rodent viruses that have been identified as etiologic agents of 2 diseases of humans: hemorrhagic fever with renal syndrome (HFRS) and nephropathiaepidemica (NE) in the Old World and Hantavirus pulmonary syndrome (HPS) in the New World. Orthohantavirus is a genus of sin- gle-stranded, enveloped, negative-sense RNA viruses in the family Hantaviridae of the order Bunyavi- rales. The important reservoir of Hantaviruses is rodents. Each virus serotype has its unique rodent host species and is transmitted to human beings with the aid of aerosolized virus, which is shed in urine, fae- ces and saliva and hardly by a bite of the contaminated host. Andes virus is the only Hantavirus identified to be transmitted from human-to-human and its major signs and symptoms include fever, headache, mus- cle aches, lungs filled with fluid etc. In the early 1993, this viral syndrome appeared in the Four Cor- ner location in the south western United States. The only accepted therapeutics for this virus is Ribavirin. Recently, serological examinations to identify Hantavirus antibodies have become most popular for in- vestigation among humans and rodent reservoirs.

Global Comprehensive outlook of Hantavirus Contagion on Humans: A review

Coronaviruses ◽  
2020 ◽  
Vol 01 ◽  
Author(s):  
Sumel Ashique ◽  
Navjot K Sandhu ◽  
Supratim Das ◽  
Sk. Niyamul Haque ◽  
Kartick Koley
Keyword(s):  
Signs And Symptoms ◽  
Western United States ◽  
Human Beings ◽  
Rodent Host ◽  
Andes Virus ◽  
Etiologic Agents ◽  
Virus Serotype ◽  
Four Corners ◽  
The Family ◽  
Negative Sense

: Hantaviruses are rodent viruses that have been identified as etiologic agents of 2 diseases of humans: haemorrhagic fever with renal syndrome (HFRS) and nephropathia epidemica (NE) in the Old World and Hantavirus pulmonary syndrome (HPS) in the New World. Orthohantavirus is a genus of single-stranded, enveloped, negative-sense RNA viruses in the family Hantaviridae of the order Bunyavirales.The important reservoir of Hantaviruses are rodents.Each virus serotype has its unique rodent host species and transmitted to human beings with the aid of aerosolized virus which is shed in urine, faeces and saliva and hardly by a bite of contaminated host. Andes virus, the only Hantavirus identified to be transmitted from human-to-human Major signs and symptoms consisting of fever, headache, muscle aches, lungs fill with fluid etc. At early 1993 this viral syndrome showed in the Four Corners location in south western United States. Only accepted therapeutics for this virus is Ribavirin. Recently serological examinations to identify Hantavirus antibodies become most popular for investigation among humans and rodent reservoirs.

TEORI KECERDASAN, PENDIDIKAN ANAK, DAN KOMUNIKASI DALAM KELUARGA

1970 ◽  
Vol 6 (1) ◽  
Author(s):  
Muskinul Fuad
Keyword(s):  
Multiple Intelligences ◽  
Educational Activity ◽  
Howard Gardner ◽  
Human Beings ◽  
Brain Functions ◽  
Starting Point ◽  
The Family ◽  
Education Today ◽  
The Brain ◽  
Spatial Logics

The education system in Indonesia emphasize on academic intelligence, whichincludes only two or three aspects, more than on the other aspects of intelligence. For thatreason, many children who are not good at academic intelligence, but have good potentials inother aspects of intelligence, do not develop optimally. They are often considered and labeledas "stupid children" by the existing system. This phenomenon is on the contrary to the theoryof multiple intelligences proposed by Howard Gardner, who argues that intelligence is theability to solve various problems in life and produce products or services that are useful invarious aspects of life.Human intelligence is a combination of various general and specific abilities. Thistheory is different from the concept of IQ (intelligence quotient) that involves only languageskills, mathematical, and spatial logics. According to Gardner, there are nine aspects ofintelligence and its potential indicators to be developed by each child born without a braindefect. What Gardner suggested can be considered as a starting point to a perspective thatevery child has a unique individual intelligence. Parents have to treat and educate theirchildren proportionally and equitably. This treatment will lead to a pattern of education that isfriendly to the brain and to the plurality of children’s potential.More than the above points, the notion that multiple intelligences do not just comefrom the brain needs to be followed. Humans actually have different immaterial (spiritual)aspects that do not refer to brain functions. The belief in spiritual aspects and its potentialsmeans that human beings have various capacities and they differ from physical capacities.This is what needs to be addressed from the perspective of education today. The philosophyand perspective on education of the educators, education stakeholders, and especially parents,are the first major issue to be addressed. With this step, every educational activity andcommunication within the family is expected to develop every aspect of children'sintelligence, especially the spiritual intelligence.

Orthodontic Aspects on the Chronological and Dental Age in Children with Down Syndrome

2018 ◽  
Vol 69 (1) ◽  
pp. 208-213
Author(s):  
Mariana Pacurar ◽  
Bogdan Dragomir ◽  
Alina Silvana Szalontay ◽  
Cristian Romanec
Keyword(s):  
Down Syndrome ◽  
Emotional Disorders ◽  
Metabolic Diseases ◽  
Genetic Disorder ◽  
Signs And Symptoms ◽  
Deciduous Teeth ◽  
Healthy Children ◽  
Dental Maturation ◽  
Children With Down Syndrome ◽  
The Family

Genetics is a key discipline in medicine, but also a clinical discipline with medical and social implications. The interest in reducing the number of genetic disorders and recognizing the risk of them repeating when a family confronts itself with a genetic anomaly becomes more and more important in the hierarchy of prophylactic emergencies. Presenting themselves as metabolic diseases (monogenic mutations) or malformations (polygenic and multifactorial heredity) because of their frequency, these disorders position themselves on an ascendant curve. They become difficult to deal with for the society, for the family and for the interested individual and cause emotional disorders. The Down syndrome is the most frequent type of genetic disorder. It is characterized by a specific set of signs and symptoms. People with Down syndrome require special medical care that, apart from the family, must include a team of doctors of various specializations and also a dentist. They are predisposed to hearing and sight disorders and thyroid problems as well. In 50% of the cases there are also anomalies of the heart, and the risk of leukaemia is 20 times higher. Some of them even develop an Alzheimer type dementia during their life. The people with Down syndrome can have an average IQ up to a moderate form of handicap. In particular, the studies on Down syndrome in dentistry are quite frequent, but they focus more on cavities, periodontal disease and hypodontia. In spite of this, the connection of Down syndrome and dental eruption is less studied. Consequently, the present study is intended to fill this missing part from the specialized literature, focusing on the relation between the Down syndrome and the chronological and dental ages in children. The health of the oral cavity is neglected in these patients, their parents focusing more on the treatment of the other systemic disorders of their children; the lack of interest is reflected in their poor oral hygiene.The trial group included 94 children with mixt dentition, aged between 6 and 12, divided as follows: 36 children with Down syndrome enrolled at the Educational Centre for Inclusive Education no. 1 of Tg. Mures and Alpha Transilvana Foundation. The chronology and the eruption sequences are subjected to certain variations and they are influenced by the presence of cavities, the premature loss or, on the contrary, the prolonged retention of deciduous teeth as well as dental anchylosis. Dental maturation is less subjected to variations, as it is a progressive, continuous and cumulative process. The presence of Down syndrome in children generates a delay in teeth eruption by 1.27 years compared to the data identified in the specialized literature and to the information obtained on the healthy children included in the study.

Phytochemistry and Pharmacology of Genus Bombax

2019 ◽  
Vol 9 (3) ◽  
pp. 184-196
Author(s):  
Deepshikha Rathore ◽  
Geetanjali ◽  
Ram Singh
Keyword(s):  
Medicinal Plants ◽  
Health Care Needs ◽  
Human Beings ◽  
Care Needs ◽  
Pharmacological Activities ◽  
Therapeutic Applications ◽  
Chemical Structures ◽  
Supportive Role ◽  
The Family ◽  
History Of

Background: The history of traditional systems of medicine goes parallel with the history of human beings. Even today people have faith in traditional systems of medicine based on medicinal plants to meet primary health care needs. Hence, the scientific evaluation and documentation of extracts and active ingredients of medicinal plants always play a supportive role in their medicinal applications. Objective: This review aims to present the phytochemicals isolated from the genus Bombax and their pharmacological applications. Methods: The literature from research and review papers was analyzed and the information was compiled to present the pharmacological applications of various secondary metabolites from genus Bombax. Results: The genus Bombax belongs to the family Malvaceae and known for its therapeutic applications. The crude, semi-purified and purified extracts of different parts of this plant have shown potential therapeutic applications. A total of 96 articles including research and review papers were referred for the compilation of isolated phytochemicals and their chemical structures. Conclusion: We systematically summarized 176 isolated compounds from the genus Bombax. The findings show that this plant shows potential towards pharmacological activities. The activities were found more from extracts than the single isolated compounds.

The Emergence of Subjectivity in the Ancient and Medieval World

2020 ◽  
Author(s):  
Jon Stewart
Keyword(s):  
Cultural History ◽  
Middle Ages ◽  
Philosophical Anthropology ◽  
Cultural Development ◽  
Western Civilization ◽  
Individual Freedom ◽  
Human Beings ◽  
The Family ◽  
The Individual ◽  
Different Cultures

This work represents a combination of different genres: cultural history, philosophical anthropology, and textbook. It follows a handful of different but interrelated themes through more than a dozen texts that were written over a period of several millennia. By means of an analysis of these texts, this work presents a theory about the development of Western Civilization from antiquity to the Middle Ages. The main line of argument traces the various self-conceptions of the different cultures as they developed historically. These self-conceptions reflect different views of what it is to be human. The thesis is that in these we can discern the gradual emergence of what we today call inwardness, subjectivity and individual freedom. As human civilization took its first tenuous steps, it had a very limited conception of the individual. Instead, the dominant principle was that of the wider group: the family, clan or people. Only in the course of history did the idea of what we know as individuality begin to emerge. It took millennia for this idea to be fully recognized and developed. The conception of human beings as having a sphere of inwardness and subjectivity subsequently had a sweeping impact on all aspects of culture, such as philosophy, religion, law, and art. Indeed, this conception largely constitutes what is today referred to as modernity. It is easy to lose sight of the fact that this modern conception of human subjectivity was not simply something given but rather the result of a long process of historical and cultural development.

scholarly journals Assessment of Knowledge and Sources of Information on Lassa Fever Infection Among the Undergraduate Students of Ebonyi State University, Nigeria

SAGE Open ◽  
2021 ◽  
Vol 11 (1) ◽  
pp. 215824402110063
Author(s):  
MaryJoy Umoke ◽  
Prince Christian Ifeanachor Umoke ◽  
Chioma Adaora Nwalieji ◽  
Rosemary N. Onwe ◽  
Ifeanyi Emmanuel Nwafor ◽  
...  
Keyword(s):  
Undergraduate Students ◽  
Signs And Symptoms ◽  
Hemorrhagic Fever ◽  
Lassa Fever ◽  
State University ◽  
Sources Of Information ◽  
Cross Sectional Survey ◽  
Cross Sectional ◽  
Endemic Diseases ◽  
Academic Level

Lassa fever is a zoonotic disease characterized by acute viral hemorrhagic fever, endemic in West Africa including Nigeria. The study assessed the knowledge and sources of information on Lassa fever infection among the undergraduate students of Ebonyi State University, Nigeria. This was a descriptive cross-sectional survey conducted among a sample of 389 students (18 years above). A self-administered questionnaire was used to collect data. Data were analyzed with SPSS (Version 20), and hypotheses were tested at p < .05 level of significance. Results showed that the majority of the students had good knowledge of Lassa fever description, 232 (60.75%); the signs and symptoms, 221 (57.9%); mode of transmission, 261 (68.41%); and preventive measures, 291 (76.13%). Radio, 23 (84.6%), and television, 307 (80.4%), were their major sources of information. Age ( p = .424), sex ( p = .082), and academic level ( p = .553) were not significant in the study, while faculty (social sciences; p = .000*) was strongly associated with the knowledge of Lassa fever. In conclusion, the overall knowledge of Lassa fever was good among students, though knowledge gaps were observed in the signs and symptoms. We recommend that health education on endemic diseases in the state be made a compulsory course as a general study (GST) in the university. Also, the internet, social media, and campus campaign be further used to educate and sensitize students on the effect of Lassa fever.

PENDIDIKAN KEIMANAN ANAK DALAM KELUARGA MENURUT ZAKIAH DARADJAT

2018 ◽  
Vol 1 (2) ◽  
pp. 110-121
Author(s):  
Rivanti Muslimawaty
Keyword(s):  
Qualitative Research ◽  
Research Methods ◽  
Religious Education ◽  
Strong Influence ◽  
Educational Institution ◽  
Qualitative Research Methods ◽  
Human Beings ◽  
The Family ◽  
The Relationship

Many parents do not understand the concept of faith education inchildren. This could be based on an assumption that children are stilltoo young to be educated in matters of faith. Whereas the family, in thiscase the parents, is an educational institution that is directly related tothe child since he was born. So there is a thought that the family isbelieved to have a very strong influence on children’s religiouseducation. This happens because the relationship that exists betweenparents and children for 24 hours is very important in education.Zakiah Daradjat is an education expert who also believes that theimportance of faith education is given to children as early as possible,so the purpose of this study is to find out how Zakiah Daradjat’sthoughts about children’s religious education are in the family. Byusing qualitative research methods, the author seeks to explain theeducation of children’s faith in the family according to ZakiahDaradjat. The author found that Zakiah Daradjat had clear thoughtsabout children’s religious education in the family, which aims to makechildren as human beings, through the six pillars of faith, with methodsof exemplification, habituation, wrong correction, erroneous quarrelsthat occur and reminding the forgotten. The evaluations carried out inthe form of memorization tests, tests of understanding and practice ofworship. This makes Zakiah Daradjat’s thoughts still relevant to beapplied in today’s life and become a reference for psrents, teachers abdother related parties.

scholarly journals A new species of Diaphanosoma Fischer, 1850 (Crustacea: Branchiopoda: Sididae) inhabits lakes of the western United States

2015 ◽  
Author(s):  
Nikolai M. Korovchinsky
Keyword(s):  
Western United States ◽  
Ventral Valve ◽  
Dorsal Part ◽  
Aquatic Fauna ◽  
The Family ◽  
Valve Margin ◽  
Regional Centers ◽  
Basal Spine ◽  
Postabdominal Claws ◽  
A New Species

<p><em>Diaphanosoma edmondsoni </em>sp. nov.  is described from material from several lakes in Washington, California, and Montana. It differs from all other known species of the genus in having a specific combination of traits: a head with conspicuously protruding dorsal part, comparatively small eye shifted ventrally, specific armament of postero-ventral valve margin, lack of thorn(s) near posterior valve margin, comparatively long distal basal spine of postabdominal claws of slightly variable shape, and occasional presence of additional large spines on the claws. This is the first endemic species of the genus (and also of the family Sididae and order Ctenopoda) recorded in the western part of North America, which along with some other cladocerans form a group of taxa highlighting this region as one of the regional centers of endemic aquatic fauna. <strong></strong></p>

scholarly journals Revisiting Orthotospovirus Phylogeny Using Whole Genomic Data and a Hypothesis for their Geographic Origin and Diversification

2020 ◽  
Author(s):  
Anamarija Butković ◽  
Rubén González ◽  
Santiago F. Elena
Keyword(s):  
Phylogenetic Relationships ◽  
Geographic Origin ◽  
Genome Shuffling ◽  
Genomic Data ◽  
Genomic Sequences ◽  
Genome Database ◽  
Evolutionary Forces ◽  
The Family ◽  
Plant Families ◽  
Negative Sense

ABSTRACTThe family Tospoviridae, a member of the Bunyavirales order, is constituted of tri-segmented negative-sense single-stranded RNA viruses that infect plants and are also able of replicating in their insect vectors in a persistent manner. The family is composed of a single genus, the Orthotospovirus, whose type species is Tomato spotted wilt virus (TSWV). Previous studies assessing the phylogenetic relationships within this genus were based upon partial genomic sequences, thus resulting in unresolved clades and a poor assessment of the roles of recombination and genome shuffling during mixed infections. Complete genomic data for most Orthotospovirus species are now available at NCBI genome database. In this study we have used 62 complete genomes from 20 species. Our study confirms the existence of four phylogroups (A to D), grouped in two major clades (A-B and C-D), within the genus. We have estimated the split between the two major clades ∼3,100 years ago shortly followed by the split between the A and B phylogroups ∼2,860 years ago. The split between the C and D phylogroups happened more recently, ∼1,465 years ago. Segment reassortment has been shown to be important in the generation of novel viruses. Likewise, within-segment recombination events have been involved in the origin of new viral species. Finally, phylogeographic analyses of representative viruses suggests the Australasian ecozone as the possible origin of the genus, followed by complex patterns of migration, with rapid global spread and numerous reintroduction events.IMPORTANCEMembers of the Orthotospovirus genus infect a large number of plant families, including food crops and ornamentals, resulting in multimillionaire economical losses. Despite this importance, phylogenetic relationships within the genus were established years ago based in partial genomic sequences. A peculiarity of orthotospoviruses is their tri-segmented negative sense genomes, which makes segment reassortment and within-segment recombination, two forms of viral sex, potential evolutionary forces. Using full genomes from all described orthotospovirus species, we revisited their phylogeny and confirmed the existence of four major phylogroups with uneven geographic distribution. We have also shown a pervasive role of sex in the origin of new viral species. Finally, using Bayesian phylogeographic methods, we assessed the possible geographic origin and historical dispersal of representative viruses from the different phylogroups.

scholarly journals A Patient with Typhoid Hepatitis

2021 ◽  
Vol 22 (2) ◽  
pp. 154-158
Author(s):  
M Vitanata Arfijanto ◽  
Isty Rindryastuti
Keyword(s):  
Blood Culture ◽  
Typhoid Fever ◽  
Gastrointestinal Symptoms ◽  
Signs And Symptoms ◽  
Hemorrhagic Fever ◽  
Liver Function Tests ◽  
Salmonella Typhi ◽  
Abnormal Liver Function ◽  
Grade Ii ◽  
Ig G

Typhoid hepatitis is typhoid fever accompanied by symptoms of jaundice, hepatomegaly and abnormal liver function tests. The incidence varies between 0.4% -26% of typhoid fever patients. We report a case of a 34-year-old male, presented with fever, epistaxis, gastrointestinal symptoms, thrombocytopenia and elevated AST/ ALT, thus the patient was first diagnosed as dengue hemorrhagic fever grade II. On day 9th the signs and symptoms were persisted, Ig M and Ig G Dengue was negative. Then we evaluated the virus marker for hepatitis and blood culture. The results were negative for HBsAg, anti HCV and Ig M anti HAV, but Salmonella typhi detected on blood culture. The patient was treated with ceftriaxone 1000mg bid iv and get better then discharged from hospital.

Sign in / Sign up

Export Citation Format

Share Document