scholarly journals Treatment Outcomes of Tuberculosis Retreatment Case and Its Determinants in West Ethiopia

2019 ◽  
Vol 13 (1) ◽  
pp. 58-64
Author(s):  
Mohammed Gebre Dedefo ◽  
Meti Teressa Sirata ◽  
Balisa Mosisa Ejeta ◽  
Getu Bayisa Wakjira ◽  
Ginenus Fekadu ◽  
...  
Keyword(s):  
Treatment Outcome ◽  
Treatment Outcomes ◽  
Developed Countries ◽  
World Health ◽  
Health Concern ◽  
P Value ◽  
Cross Sectional ◽  
Retreatment Case ◽  
Poor Treatment ◽  
Poor Treatment Outcome

Background: Tuberculosis (TB) is a major public health concern in the developing world. World Health Organization’s (WHO’s) list of 30 high TB burden countries accounted for 87% of the world’s cases. The annual infection rate in developing countries reached 2% or more; where as in developed countries this figure is 0.5%. Objective: The objective of this study is to assess treatment outcomes of tuberculosis retreatment case and its determinants at Nekemte Referral Hospital (NRH), West Ethiopia. Methods: A retrospective cross-sectional study was conducted. All registered adult TB patients under retreatment regimen who were treated at NRH TB clinics from January 2014 to December 2017 were included in this study. A multiple logistic regression was used to assess the significance and strength of association. A P-value <0.05 was used as statistically significant. Results: The prevalence of retreatment case was 12.12%. Of 219 study participants 159(72.6%) were patients with relapse, 43(19.6%) were with retreatment after failure and 17(7.8%) were patients who return after loss to follow-up. On multivariable logistic analysis poor treatment outcome was more likely to occur among patients with positive Acid Fast Bacilli (AFB) result at 5th month (Adjusted odds ratio (AOR =4.3, 95%, (1.8-10.0) p=0.001) and patients taking category 1 (2ERHZ/4RH) drugs (AOR=2.1, 95% CI= (1.1-4.5) p=0.048). Conclusion: This study showed that treatment outcomes of TB retreatment case were below standard set by the WHO. Factors that were significantly associated with poor treatment outcome were positive AFB resulting at 5th month and patients on category 1(2ERHZ/4RH).

scholarly journals Clinical pattern and predictors of stroke treatment outcome among hospitalised patients who had a stroke at Felege Hiwot comprehensive specialised hospital, northwest Ethiopia: a retrospective cross-sectional study

BMJ Open ◽  
2020 ◽  
Vol 10 (12) ◽  
pp. e040238
Author(s):  
Belayneh Kefale ◽  
Amien Ewunetei ◽  
Mulugeta Molla ◽  
Gobezie Temesgen Tegegne ◽  
Amsalu Degu
Keyword(s):  
Treatment Outcome ◽  
Treatment Outcomes ◽  
Medical Records ◽  
Cross Sectional Study ◽  
Northwest Ethiopia ◽  
Cross Sectional ◽  
Stroke Treatment ◽  
Clinical Pattern ◽  
Hospitalised Patients ◽  
Poor Treatment

ObjectivesThis study aimed to assess the clinical pattern and predictors of stroke treatment outcomes among hospitalised patients in Felege Hiwot comprehensive specialised hospital (FHCSH) in northwest Ethiopia.DesignA retrospective cross-sectional study.SettingThe study was conducted medical ward of FHCSH.ParticipantsThe medical records of 597 adult patients who had a stroke were included in the study. All adult (≥18 years) patients who had a stroke had been admitted to the medical ward of FHSCH during 2015–2019 were included in the study. However, patients with incomplete medical records (ie, incomplete treatment regimen and the status of the patients after treatment) were excluded in the study.ResultsIn the present study, 317 (53.1%) were males, and the mean age of the study participants was 61.08±13.76 years. About two-thirds of patients (392, 65.7%) were diagnosed with ischaemic stroke. Regarding clinical pattern, about 203 (34.0%) of patients complained of right-side body weakness and the major comorbid condition identified was hypertension (216, 64.9%). Overall, 276 (46.2%) of them had poor treatment outcomes, and 101 (16.9%) of them died. Patients who cannot read and write (AOR=42.89, 95% CI 13.23 to 111.28, p<0.001), attend primary school (AOR=22.11, 95% CI 6.98 to 55.99, p<0.001) and secondary school (AOR=4.20, 95% CI 1.42 to 12.51, p<0.001), diagnosed with haemorrhagic stroke (AOR=2.68, 95% CI 1.62 to 4.43, p<0.001) and delayed hospital arrival more than 24 hours (AOR=2.92, 95% CI 1.83 to 4.66, p=0.001) were the independent predictors of poor treatment outcome.ConclusionsApproximately half of the patients who had a stroke had poor treatment outcomes. Ischaemic stroke was the most predominantly diagnosed stroke type. Education status, types of stroke and the median time from onset of symptoms to hospitalisation were the predictors of treatment outcome. Health education should be given to patients regarding clinical symptoms of stroke. In addition, local healthcare providers need to consider the above risk factors while managing stroke.

scholarly journals Childhood Tuberculosis Treatment Outcome and Its Association with HIV-Co infection in Ethiopia, A Systematic Review and Meta-analysis

2019 ◽  
Author(s):  
Getaneh Mulualem Belay ◽  
Chalachew Adugna Wubneh
Keyword(s):  
Systematic Review ◽  
Treatment Outcome ◽  
Successful Treatment ◽  
Meta Analysis ◽  
Tuberculosis Treatment ◽  
World Health ◽  
Successful Treatment Outcome ◽  
Poor Treatment ◽  
Poor Treatment Outcome ◽  
Tuberculosis Treatment Outcome

Abstract Introduction Globally around one million children are infected with Tuberculosis. Childhood Tuberculosis is underestimated due diagnosis challenge. HIV infection can affect the TB disease progression and treatment outcome.Objectives The aim of this systematic review and meta-analysis is to determine the pooled estimates of childhood tuberculosis treatment outcome and to analyze the impact of HIV-co infection.Methods We searched all available articles using PubMed, Google scholar and a web of science. Additionally, reference lists of included studies and Ethiopian institutional research repositories were used. Searching was limited to studies conducted in Ethiopia and published in English language. Cohort, cross-sectional and case-control studies were included. A weighted inverse variance random effects- model was used. The overall variations between studies were checked by heterogeneity test Higgins’s method (I 2 ). All included studies were assessed with the JBI quality appraisal criteria. Publication bias was checked with the funnel plot and Egger’s regression test.Result A total of 6 studies with 5,389 participants were included in this systematic review and meta-analysis. The overall pooled estimate of successful treatment outcome was found to be 79.54% (95% CI: 73.00, 86.07). Of which 72.44% were treatment completed. Moreover, this study revealed that the treatment failure, defaulter and death were 0.15%, 5.36%, and 3.54%, respectively. Poor treatment outcome was higher among children with HIV co infection with an odds ratio of 3.15 (95% CI: 1.67, 5.94) as compared to HIV negative children.Conclusion The rate of successful treatment outcome of childhood tuberculosis in Ethiopia found to be low compared to the threshold suggested by the world health organization. HIV co infection is significantly associated with poor treatment outcome. Therefore, special attention better to be given for children infected with HIV.

scholarly journals Predictors of Treatment Outcomes among Pediatric Patients Hospitalized with Pneumonia in Tikur Anbessa Specialized Hospital, Addis Ababa, Ethiopia

2021 ◽  
Vol 2021 ◽  
pp. 1-7
Author(s):  
Hilina Tsegaw ◽  
Mohammed Yimam ◽  
Dejen Nureye ◽  
Workineh Woldeselassie ◽  
Solomon Hambisa
Keyword(s):  
Treatment Outcome ◽  
Sample Size ◽  
Treatment Outcomes ◽  
Pediatric Patients ◽  
Addis Ababa ◽  
Good Treatment Outcome ◽  
Specialized Hospital ◽  
Tikur Anbessa Specialized Hospital ◽  
Poor Treatment ◽  
Poor Treatment Outcome

Background. Pneumonia remains the leading cause of hospitalization and mortality in young children in low- and middle-income countries. This study is aimed to assess predictors of treatment outcomes among pediatric patients hospitalized with pneumonia in Tikur Anbessa Specialized Hospital, Addis Ababa, Ethiopia. Methods. A facility-based retrospective cross-sectional study was conducted among pediatric patients admitted with pneumonia, considering patient medical charts recorded for a 1-year period from February 2017 to February 2018. The sample size was computed based on a single population proportion formula and giving a total sample size of 207. The systematic random sampling method was employed to select patient cards from the sampling frame. The data extraction format was used to extract any relevant information from patient chart. The processed data were analyzed by using Statistical Package for Social Sciences (SPSS, version 21). Descriptive statistics were used to summarize the patients’ baseline characteristics and related information. The logistic regression model was fitted to determine factors associated with treatment outcomes. To identify predictors of poor treatment outcome, the level of significance was set at P < 0.05 . Results. From a total of 207 patient charts reviewed, more than half (55.6%) of the study participants were males. Majority of patients, 130 (62.8%), were in the age range of 1 month–11 months. Furthermore, 191 (92.3%) patients had good treatment outcome. Patients who treated with ceftriaxone + azithromycin were less likely to have poor treatment outcome compared with patients who were placed on crystalline penicillin (AOR = 0.86, 95% CI 0.01–0.83). On the contrary, patients who stayed ≥ 8 days were about 14.3 times more likely to have poor treatment outcome compared with patients who stayed ≤ 3 days (AOR = 14.3, 95% CI 1.35–151.1). Conclusion. Even though the study revealed good treatment outcome among the pediatric patients, particular consideration should be given to children in need of other interventions.

scholarly journals Relationship Of Food Consumption With Disease Hypertension In Elderly at Panti Jompo Yayasan Guna Budi Bakti Medan Labuhan

2019 ◽  
Vol 1 (1) ◽  
pp. 29-34
Author(s):  
Ihsan Isan Kurniawan
Keyword(s):  
Nursing Home ◽  
Food Consumption ◽  
The Elderly ◽  
Developed Countries ◽  
World Health ◽  
P Value ◽  
Chi Square ◽  
Cross Sectional ◽  
Relationship Of ◽  
The Relationship

Based on WHO data (World Health Organition), around 972 million people in the world or 26.4% of people worldwide have hypertension, the figure is likely to increase to 29.2% in 2025. Of the 972 million hypertension, 333 million are in developed countries and the remaining 639 are in developing countries including Indonesia. This research aims to determine the relationship of food consumption with hypertension in the elderly at the Nursing Home in Medan Labuhan Foundation for the Budi Bakti in 2018. The research design is an analytical survey to determine the relationship between two variables with a cross sectional approach. The population in this study were patients who suffered from hypertension in the Nursing Home Foundation Medan Labuhan For Bakti Budi Bakti in 2018 totaling 64 people and a sample of 64 people and using total sampling. The test in this study is Chi-square test. The results of this study showed that 61 (95.3%) of the majority had poor food consumption, and the majority of hypertensive diseases were as heavy as 45 respondents (70.3%), bivariate statistic test results showed that there was a relationship between food consumption and hypertension with p value -Velue = 0.004.     The conclusion in this study is that there is a relationship between food consumption and hypertension is p-velue = 0.004 α 0.05, so Ha is accepted. Suggestions for further researchers to be able to examine the causes and relationship of food consumption with hypertension.

scholarly journals Multi-Drug Resistant Tuberculosis Treatment Outcome and Associated Factors in Addis Ababa, Ethiopia: A Retrospective Cross-Sectional Study

2020 ◽  
Author(s):  
Tadesse Alemu Bekele ◽  
Getasew Amogne Aynalem ◽  
Trhas Tadesse Berhe
Keyword(s):  
Treatment Outcome ◽  
Cross Sectional Study ◽  
Drug Resistant ◽  
Sectional Study ◽  
Cross Sectional ◽  
Drug Resistant Tuberculosis ◽  
Resistant Tuberculosis ◽  
Multi Drug Resistant Tuberculosis ◽  
Poor Treatment ◽  
Poor Treatment Outcome

Abstract BackgroundDrug-resistant tuberculosis continues to be a public health threat around the globe especially in developing countries. In 2018, the number of new cases of rifampicin-resistant tuberculosis was half a million and about 78% of them had multi-drug resistant tuberculosis. In Ethiopia, the overall proportion of multi-drug resistant tuberculosis was 11.6%. The latest treatment outcome data for people with multi-drug resistant tuberculosis show a global treatment success rate of 56%. Therefore, this study was aimed at assessing multi-drug resistant tuberculosis treatment outcomes and associated factors at St. Peter Specialized Hospital, Ethiopia, 2019. MethodsA retrospective cross-sectional study was done. A total of 384 patient medical charts selected by simple random sampling method were reviewed. The data was collected using a checklist from the patients’ medical charts. The collected data were analyzed with SPSS version 23 computer software package. Summary statistics of a given data for each variable were calculated. A logistic regression model was used to measure the association between the outcome and the predictor variable. Statistical significance was declared at p-value<0.05. Direction and strength of association were expressed using OR and 95% CI. ResultFrom a total of 384 patients, the majority of 245(63.8%) of the study subjects were females. The rate of poor treatment outcome was 173(45.1%). Male patients and patients in the age category of 39-60 years were less likely to have poor treatment outcome compared to female patients and patients in the age category of 18-38 years (AOR = 0.43, 95%CI (0.19, 0.10) and (AOR = 0.28, 95%CI (0.15, 0.52) respectively. Patients with a history of second-line TB drug resistance are more likely to have poor treatment outcomes (AOR = 3.81, 95%CI (1.84, 7.91). Poor treatment outcome was higher among patients with longer treatment duration (AOR = 3.23, 95%CI (1.82, 5.74) compared to patients with short treatment duration. ConclusionThe proportion of poor treatment outcome in patients with multi-drug resistant tuberculosis was high. Therefore, a concerted effort should be done at all levels to improve the treatment outcome of the MDR-TB.

scholarly journals Management practice, and treatment outcome and its associated factors among hospitalized stroke patient at Ambo University Referral Hospital, Ethiopia: an Institutional Based Cross Sectional Study

2019 ◽  
Author(s):  
Belayneh Kefale ◽  
Guye Betero ◽  
Gobezie Temesgen ◽  
Amsalu Degu
Keyword(s):  
Treatment Outcome ◽  
Associated Factors ◽  
Management Practice ◽  
Cross Sectional Study ◽  
Stroke Patients ◽  
Cross Sectional ◽  
Good Treatment Outcome ◽  
Poor Treatment ◽  
Poor Treatment Outcome ◽  
Study Participants

Abstract Background: Although stroke has been consistently reported as one of the three leading causes of morbidity and mortality in the past few years in Ethiopia, there is a paucity of data regarding to stroke treatment outcomes and associated factors. Hence, this study was aimed to assess management practice, and treatment outcome and its associated factors among hospitalized stroke patients.Method an institutional based cross sectional study was conducted among 111 hospitalized stroke patients in the medical ward of Ambo University Referral Hospital(AURH), who had been hospitalized for the last three years (March 30/2016- May30/2019). All patients diagnosed with stroke and hospitalized in the medical ward of AURH were included in the study. Data were analyzed with SPSS version 25.0 statistical software. Bivariate and multivariate binary logistic regression analysis was conducted to identify the predictors of poor treatment outcome.Result The present study showed that ischemic stroke was the most prevalent (80.1%) form of stroke diagnosed in the study setting. Nonetheless, 18.2% of patients were diagnosed with hemorrhagic stroke. Among 111 study participants, 69 (62.2%) patients had good treatment outcome. From 42(37.8%) study participants with poor treatment outcome, 18(42.8%) were dead and 12 (28.6%) were with disability and left against medical advice on self and family request while the remaining 12 (28.6%) were referred to other higher health facility. Social history (substance abuse P=00.046, AOR=2.684, 95%CI 1.091-6.604), age (P=0.026, AOR= 3.256, 95%CI = 1.145-9.260) and chief compliant (P=0.009, AOR=0.254, 95%CI=0.091-0.708) were the predictors of treatment outcome among hospitalized stroke patients. Other variables like types of stroke, co-morbidity, and others did not show significant association with treatment outcome.Conclusion The present study showed that ischemic stroke was the most predominantly diagnosed type of stroke in our setting. Acetyl salicylic acid and ACE inhibitor based regimens were frequently used in the management of stroke and hypertension, respectively. Nearly one third of the study participants had good treatment outcome. Nonetheless, death was reported in 16.2% of hospitalized stroke patients in the study setting. Being older and substance abusers, and the presence of hemiparesis during the initial hospital admission were significant predictors of poor treatment outcome.

scholarly journals Treatment Outcome and Its Determinants among Patients Admitted to Stroke Unit of Jimma University Medical Center, Southwest Ethiopia

2020 ◽  
Vol 2020 ◽  
pp. 1-8
Author(s):  
Ameha Zeleke Zewudie ◽  
Tolcha Regasa ◽  
Solomon Hambisa ◽  
Dejen Nureye ◽  
Yitagesu Mamo ◽  
...  
Keyword(s):  
Risk Factors ◽  
Treatment Outcome ◽  
Treatment Outcomes ◽  
Stroke Unit ◽  
Hemorrhagic Stroke ◽  
Medical Center ◽  
Stroke Patients ◽  
Poor Treatment ◽  
Poor Treatment Outcome ◽  
Jimma University

Background. Stroke is a public health problem in Ethiopia. Despite the high prevalence of stroke in Ethiopia, there is a paucity of data with regard to drug treatment, treatment outcome, and risk factors of poor treatment outcome of stroke. Hence, this study is aimed at assessing treatment outcome and its determinants among patients admitted to stroke unit of Jimma University Medical Center (JUMC). Methods. A two-year hospital-based retrospective cross-sectional study was employed to analyze the medical records of patients admitted with stroke to stroke unit of Jimma University Medical Centre from February 1st, 2016 to March 30th, 2018. Data was entered by Epidata manager version 4.0.2 and analyzed by SPSS version 24. Multivariable logistic regression analysis with the backward stepwise approach was done to identify independent predictors of poor treatment outcome of stroke. Variables with P value less than 0.05 were considered as statically significant determinants of poor treatment outcome. Results. Of 220 patients with stroke admitted to the Jimma University, 67.30% were male. Nearly two thirds (63.18%) of them had poor treatment outcomes. Dyslipidimics were administered to 60% of the patients, and the most popular antiplatelet used was aspirin, which was prescribed to 67.3% the patients. Age ≥ 65   adjusted   odd   ratio ((AOR): 2.56; 95% CI: 1.95-9.86, P = 0.001 ), presence of comorbidity (AOR: 5.25; 95% CI: 1.08-17.69, P < 0.001 ), admission with hemorrhagic stroke (AOR: 18.99; 95% CI: 7.05-42.07, P < 0.001 ), and admission to the hospital after 24 hour of stroke onset (AOR: 4.98; 95% CI: 1.09-21.91, P = 0.03 ) were independent predictors of poor treatment outcomes. Conclusion. Substantial numbers of stroke patients had poor treatment outcomes. Elderly patients, patients diagnosed with hemorrhagic stroke, patients with comorbidity, and those with delayed hospital admission were more likely to have poor treatment outcome. Hence, frequent monitoring and care should be given for the aforementioned patients. Awareness creation on the importance of early admission should be delivered particularly for patients who have risk factors of stroke (cardiovascular diseases).

scholarly journals Visceral Leishmaniasis Treatment Outcome and Associated Factors in Northern Ethiopia

2019 ◽  
Vol 2019 ◽  
pp. 1-7
Author(s):  
Kidu Gidey ◽  
Desalegn Belay ◽  
Berhane Yohannes Hailu ◽  
Tesfaye Dessale Kassa ◽  
Yirga Legesse Niriayo
Keyword(s):  
Logistic Regression ◽  
Regression Analysis ◽  
Treatment Outcome ◽  
Treatment Outcomes ◽  
Associated Factors ◽  
Northern Ethiopia ◽  
Duration Of Illness ◽  
Long Duration ◽  
Poor Treatment ◽  
Poor Treatment Outcome

Background. Visceral leishmaniasis (VL), one of the most neglected tropical diseases, is placing a huge burden on Ethiopia. Despite the introduction of antileishmanial drugs, treatment outcomes across regions are variable due to drug resistance and other factors. Thus, understanding of VL treatment outcomes and its contributing factors helps decisions on treatment. However, the magnitude and the risk factors of poor treatment outcome are not well studied in our setting. Therefore, our study was designed to assess treatment outcomes and associated factors in patients with VL. Materials and Methods. A cross-sectional study was conducted in VL patients admitted between June 2016 and April 2018 to Ayder Comprehensive Specialized Hospital, Tigray, Northern Ethiopia. Data was collected through chart review of patient records. Logistic regression analysis was used to identify factors associated with poor treatment outcome. Results. A total of 148 VL patients were included in the study. The mean age (SD) of the patients was 32.86 (11.9) years; most of them (94.6%) were male patients. The proportion of poor treatment outcome was 12.1%. Multivariable logistic regression analysis showed that long duration of illness (> four weeks) (adjusted odds ratio (AOR): 6.1 [95% confidence interval (CI); 1.3-28.6], p=0.02) and concomitant tuberculosis (TB) infection (AOR 4.6 [95% CI; 1.1-19.1], p=0.04) were the independent predictors of poor treatment outcome. Conclusions. Poor treatment outcome was observed in a considerable proportion of VL patients. Long duration of illness and coinfection with TB were associated with poor VL treatment outcome. Hence, early diagnosis and effective prompt treatment are important to improve treatment outcomes among VL patients. Special attention should also be given in the treatment of VL/TB coinfected patients in our setting.

scholarly journals Patterns of large-vessel lesions are associated with treatment outcomes in large-vessel giant cell arteritis

2021 ◽  
Author(s):  
Takahiko Sugihara ◽  
Haruhito A Uchida ◽  
Hajime Yoshifuji ◽  
Yasuhiro Maejima ◽  
Taio Naniwa ◽  
...  
Keyword(s):  
Treatment Outcome ◽  
Treatment Outcomes ◽  
Large Vessel ◽  
Poor Treatment ◽  
Group 3 ◽  
Group 2 ◽  
Subclavian Lesions ◽  
Poor Treatment Outcome ◽  
Mean Time ◽  
Group 1

Abstract ObjectiveTo evaluate whether the distribution of large-vessel lesions (LVLs) in giant cell arteritis (GCA) is associated with poor treatment outcomes.MethodsIn a retrospective, multi-centric, nationwide registry of GCA patients treated with glucocorticoids between 2007 and 2014, 68 newly-diagnosed patients with LVLs were identified by imaging. Non-achievement of clinical remission by week 24 and/or relapse within 104 weeks were primarily evaluated. Factors influencing the poor treatment outcome were analyzed using Cox proportional hazard modeling. Cumulative rates and median time to the first event were analyzed by the Kaplan-Meier method and log-rank testing.ResultsAortic lesions were detected in 72.1% of the 68 GCA patients with LVLs (defined as group 2). Patients without aortic lesions were classified as having large-vessel GCA with subclavian lesions (group 1) or atypical large-vessel GCA without subclavian lesions (group 3). The mean age and proportions of PMR in group 3 were higher than those in the other two groups. Cranial lesions were observed in 66.7%, 55.1%, and 80.0% of patients in groups 1, 2 and 3, respectively. In group 2, 73.5% had lesions in both the aorta and aortic branches. Group 1 had axillary lesions in 33.3%, and carotid lesions in 44.4%. Atypical LVLs in group 3 included pulmonary, hepatic or mesenteric lesions in addition to carotid lesions. Baseline doses of GCs were not different across the groups. Mean time to achievement of low-dose GC treatment (prednisolone ≤5 mg/day) was also not significantly different between the groups. The cumulative rate of poor treatment outcome over the two years was 11.1%, 55.3% and 88.0% in the groups 1, 2 and 3, respectively; mean time to the events was significantly different among the groups. Multivariable analysis showed that the risk of poor treatment outcome was significantly higher in the group 3.ConclusionsThe distribution of LVLs was associated with treatment outcomes in large-vessel GCA. In addition to subclavian arteries, lesions in aorta and aortic branches other than subclavian arteries should be evaluated by imaging for large-vessel GCA. The pattern of LVLs determined by imaging should be considered when determining treatment strategies for GCA.

Maternal Knowledge Factor, Maternal Age and Maternal Parity Associated with Genesis of Normal Delivery at Palembang Hospital of Bari Year 2017

2018 ◽  
Vol 1 (1) ◽  
pp. 43-50
Author(s):  
Juliana Widyastuti Wahyuningsih
Keyword(s):  
Maternal Age ◽  
World Health ◽  
Survey Method ◽  
P Value ◽  
Maternal Knowledge ◽  
Cross Sectional ◽  
Normal Delivery ◽  
Significance Level ◽  
Birth Canal ◽  
Maternal Parity

Childbirthis a processLabor of opening and depleting the cervix and the fetus down into the birth canal. Birth is a process in which the fetus and amniotic are pushed out through the birth canal. (Sarwono, 2008). According to the World Health Organization (WHO) estimates more than 585,000 mothers annually die during pregnancy or childbirth. Indonesia Health Demographic Survey (SDKI) Survey in 2012, Maternal Mortality Rate in Indonesia is still high at 359 per 100,000 live births. The purpose of this study is the knowledge of maternal knowledge, maternal age, and maternal parity associated with normal birth events at Palembang Bari Hospital 2017. This study used analytical survey method with cross sectional approach. The population in this study were all maternal mothers at the Palembang Bari Hospital in 2017. Sampling in the study was conducted non-randomly with the technique of "Accidental Sampling". Data analysis was done univariat and bivariate with Chi-Square statistical test with significance level α = 0,05. The result of this research shows that there is correlation between mother's knowledge with normal delivery incidence with p value 0,001, there is correlation between mother age with normal delivery incidence with p value 0,009, there is relation between mother parity with normal delivery incidence with p value 0,001. From result of this research hopes healthcare workers can improve normal delivery care services and more often to carry out maternal safety counseling.

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