Medicinal Plants: The Magic of Wound Healing Activity

2017 ◽  
Vol 2 (3) ◽  
pp. 186-206
Author(s):  
Sharangi Baran
2017 ◽  
Vol 2017 ◽  
pp. 1-6 ◽  
Author(s):  
Sara H. Freiesleben ◽  
Jens Soelberg ◽  
Nils T. Nyberg ◽  
Anna K. Jäger

The present study was carried out to investigate the wound healing potentials of 17 medicinal plants historically used in Ghana for wound healing. Warm and cold water extracts were prepared from the 17 dried plant species and tested in vitro in the scratch assay with NIH 3T3 fibroblasts from mice. The wound healing scratch assay was used to evaluate the effect of the plants on cell proliferation and/or migration in vitro, as a test for potential wound healing properties. After 21 hours of incubation increased proliferation and/or migration of fibroblasts in the scratch assay was obtained for 5 out of the 17 plant species. HPLC separation of the most active plant extract, which was a warm water extract of Philenoptera cyanescens, revealed the wound healing activity to be attributed to rutin and a triglycoside of quercetin. The present study suggests that Allophylus spicatus, Philenoptera cyanescens, Melanthera scandens, Ocimum gratissimum, and Jasminum dichotomum have wound healing activity in vitro.


2018 ◽  
Vol 2018 ◽  
pp. 1-9 ◽  
Author(s):  
Wubante Demilew ◽  
Getnet Mequanint Adinew ◽  
Seyfe Asrade

Background. Medicinal plants play indispensable roles to treat various ailments. Acanthus polystachyus is one of the medicinal plants used traditionally for treatment of wounds. However, there were no scientific reports documented so far on the wound healing activities of this plant. Thus, the present study provides a scientific evaluation for the wound healing potential of the crude extract of A. polystachyus leaves. Methods. The crude extraction was carried out using 80% methanol. The crude extract was prepared in 5% (w/w) and 10% (w/w) ointment and evaluated for wound healing activity using excision, infected, and incision wound models in Swiss albino mice. Results. Both 5%  and 10% (w/w) ointments significantly reduced period of epithelialization and increased wound contraction rate and tensile strength compared to the negative control group (P < 0.05). The wound healing activity of 10% (w/w) ointment treated group was greater than 5% (w/w) and nitrofurazone ointment treated groups in S. aureus infected wound model. Conclusion. These results demonstrate that the crude extract of A. polystachyus leaves possesses wound healing activities. This justifies the traditional claimed use of the plant for treating uninfected and infected wounds caused by S. aureus.


Author(s):  
.Dr Abhijeet Patil ◽  
Dr Pragati Kasat ◽  
Dr Rajesh Gundre

Among all this Samhitas of Ayurveda Charaka samhita is a vast treasure of knowledge regarding medicinal plants. Charaka is the first person who could classify the existing plants, into pharmacological categories and given 50 classes which are known as Dashemani. Acharaya Charaka has mentioned Yashtimadhu in the chief 11 Dashemanis which highlights its own importance in Ayurveda. The duration taken for complete wound contraction in Yashtimadhu ointment  was much earlier when compare with standard betadine ointment. This was innovative medium of Yashtimadhu ointment preparation for topical application so further clinical study should be conduct. The result of the Yashtimadhu ointment is having potent wound healing activity.


Author(s):  
V.S. Borkar ◽  
Senthil K. Kumaran ◽  
Senthil KL. Kumar

1997 ◽  
Vol 55 (3) ◽  
pp. 193-200 ◽  
Author(s):  
León F. Villegas ◽  
Irma D. Fernández ◽  
Holger Maldonado ◽  
Rosa Torres ◽  
Alfonso Zavaleta ◽  
...  

Author(s):  
Pal Gogoi ◽  
Moksood Ahmed Laskar ◽  
Saikat Sen ◽  
Biplab Kumar Dey ◽  
Rejwan Ahmed Choudhury ◽  
...  

Wound healing is a vital physiological process that helps to retain the integrity of the skin after it has been damaged, whether by accident or by a deliberate operation. In Tinsukia district, Assam, tribal people and folklore traditions employ a wide variety of plants/plant extracts/decoctions or pastes to cure wounds. This study is designed to explore the ethnomedicinal plants used for the wound healing properties by the people of Tinsukia district, Assam. The Documentation of potential ethnobotanical information of traditionally used medicinal plant with wound healing activity will facilitates the scientific evaluation to look forward into a leading scientific prospect for the development of new herbal therapy for wound healing.


2018 ◽  
Vol 9 (2) ◽  
pp. 42-78
Author(s):  
Tarun Sharma ◽  
Bhargav Bhide ◽  
Rabinarayan Acharya

Plants are traditionally being used as a source of medicine by indigenous people of different ethnic groups inhabiting various terrains for the control of various ailments effecting both human and animals. Recently, focus on plant research has been increased, all over the world, due to the huge potential of medicinal plants used in various traditional systems. Wounds are the result of injuries to the skin that disrupt the soft tissue. Various plants have been used in treatment of wounds over the years in many tribal areas. Many ethno botanical survey reports and books have been published highlighting the use of plant as a whole or its various parts for the management of wounds. Recent research shows that some of these plants are established either experimental or clinical studies for their wound healing activities. Single hand information regarding these plants with their specific parts used for wound healing activity is lacking. Hence, the present study is an attempt to compile the leaf drugs reported for their wound healing activity from 85 research articles and 14 books related to ethno medicine and ethno botany. It is observed that ethno medicinal plants belonging to 100 families (Asteraceae-51, Fabaceae-38, Euphorbiaceae-34, Lamiaceae-19, Rubiaceae-17 etc.) are reported for their wound healing activity. Among them 202 plants reported for topical application, 11 for oral administration and 9 for both (oral and topical).  


Molecules ◽  
2020 ◽  
Vol 25 (8) ◽  
pp. 1828 ◽  
Author(s):  
Eugénia Solange Santos ◽  
Ângelo Luís ◽  
Joana Gonçalves ◽  
Tiago Rosado ◽  
Luísa Pereira ◽  
...  

Julbernardia paniculata and Pterocarpus angolensis are two plant species with important application in African traditional medicine, particularly in Angola, in the treatment of several diseases. However, scientific studies concerning these species are scarce. The goal of this work was to know better which medicinal approaches are used by the Huíla population in Angola by means of ethnobotanical surveys. Furthermore, extracts of both plants were phytochemically characterized. Antioxidant, anti-inflammatory, wound-healing activities, and potential cytotoxicity were also studied. With this study it was possible to verify that 67% of the individuals that use medicinal plants are women, and their main therapeutic uses are the treatment of problems of the digestive system and skin disorders. Barks of J. paniculata and leaves of P. angolensis are the most often used plant parts. Through high-performance liquid chromatography coupled to diode-array detector (HPLC-DAD) and GC-MS it was possible to characterize the chemical composition of the two species, which are rich in phenolic compounds, terpenes, terpenoids, sesquiterpenoids and fatty acids. Both plants showed to possess antioxidant, anti-inflammatory proprieties, and wound-healing activity. To the best of our knowledge, this is the most comprehensive study of these two species and the first ethnobotanical and ethnopharmacological study of medicinal plants from this region of Angola.


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