scholarly journals PROFILE OF HISTORY OF FEBRILE SEIZURE IN PATIENTS WITH EPILEPSY

2022 ◽  
Vol 8 (1) ◽  
pp. 21-24
Author(s):  
Rayhan Muhammad Basyarahil ◽  
Wardah Rahmatul Islamiyah ◽  
Prastiya Indra Gunawan

Background: Febrile seizure is convulsions with fever (temperature ³38°C) with no central nervous system infection that commonly found in children (6-60 months). Febrile seizures do not always mean the child has epilepsy. However, febrile seizures can be a possible long-term risk factor for epilepsy. Objective: The objective of this study is to know the profile of febrile seizure in patients with epilepsy. Methods: A retrospective descriptive study on 23 patients with epilepsy in the EEG Department of Neurology, Dr. Soetomo General Hospital, Surabaya, Indonesia in the period 2018-2019 based on inclusion and exclusion criteria. The total number of epilepsy patients is 849 patients, 216 of whom had a history of febrile seizure. Among 216 epilepsy patients who had a history of febrile seizures, 23 of them were qualified as the sample. The sampling technique used was total population sampling. The instrument of this research is the patients’ medical record. Data analysis is carried out descriptively. Results: The characteristics of the history of febrile seizures that found in patients with epilepsy are more patients are male, have the age of onset on less than 2 years old, have the body temperature more than 38.3°C, have the seizure duration less than 15 minutes, have focal seizures, have recurrent seizures in 24 hours, have a history of more than one febrile seizure, have accompanying neurological disorders, and have no family history of epilepsy. Conclusion: Febrile seizure is still becoming a concern because there is a possibility that it may develop into epilepsy. Even though, not all children who experience febrile seizure will generate epilepsy.

PEDIATRICS ◽  
1990 ◽  
Vol 86 (4) ◽  
pp. 624-624
Author(s):  
JOHN M. FREEMAN

A seizure, even a febrile seizure, is terrifying to the family. Seeking reassurance that their child will not die and does not have epilepsy, parents turn to their physician. What is he or she to do? Often the physician prescribes medication "to prevent further seizures" and then reassures the family that the child will be fine if the medicine is given daily as directed. Both the recommendation and the reassurance are wrong. A Consensus Development Conference on Febrile Seizures held by the National Institutes of Health in 19801 concluded that they would only "consider" anticonvulsant prophylaxis when the child (1) had abnormal neurologic development, (2) had long or focal seizures, (3) had more than two seizures in 24 hours, (4) had a history of nonfebrile seizures in parent or sibling, or (5) was younger than 1 years of age.


PEDIATRICS ◽  
1996 ◽  
Vol 98 (2) ◽  
pp. 216-225 ◽  
Author(s):  
Shlomo Shinnar ◽  
Anne T. Berg ◽  
Solomon L. Moshe ◽  
Christine O'Dell ◽  
Marta Alemany ◽  
...  

Objective. To assess the long-term recurrence risks after a first unprovoked seizure in childhood. Methods. In a prospective study, 407 children who presented with a first unprovoked seizure were then followed for a mean of 6.3 years from the time of first seizure. Results. One hundred seventy-one children (42%) experienced subsequent seizures. The cumulative risk of seizure recurrence was 29%,37%,42%, and 44% at 1,2,5, and 8 years, respectively. The median time to recurrence was 5.7 months, with 53% of recurrences occurring within 6 months, 69% within 1 year, and 88% within 2 years. Only 5 recurrences (3%) occurred after 5 years. On multivariable analysis, risk factors for seizure recurrence included a remote symptomatic etiology, an abnormal electroencephalogram (EEG), a seizure occurring while asleep, a history of prior febrile seizures, and Todd's paresis. In cryptogenic cases, the risk factors were an abnormal EEG and an initial seizure during sleep. In remote symptomatic cases, risk factors were a history of prior febrile seizures and age of onset younger than 3 years. Risk factors for late recurrences (after 2 years) were etiology, an abnormal EEG, and prior febrile seizures in the overall group and an abnormal EEG in the cryptogenic group. These are similar to the risk factors for early recurrence. Conclusions. The majority of children with a first unprovoked seizure will not have recurrences. Children with cryptogenic first seizures and a normal EEG whose initial seizure occurs while awake have a particularly favorable prognosis, with a 5-year recurrence risk of only 21%. Late recurrences do occur but are uncommon.


2018 ◽  
Vol 1 (3) ◽  
Author(s):  
Ernawaty Siagian ◽  
Vera Manalu

Febrile seizure rate on toddler was quite high and tended to increase every year. This was because as toddler experiencing febrile seizures they were not properly handled by the parents. Febrile seizure in toddler if not treated quickly can affect the increasing in seizure frequency and can cause death. The capability of mother in handling febrile seizure must be based on the right knowledge of febrile seizure. The purpose of this study was to determine the level of knowledge of the mother before and after health education based on 10 steps in handling febrile seizure on toddler in Bandar Lampung Adventist Hospital. Experimental research method with one group pretest-posttest designed with random sampling technique approach involving 80 mothers with 0 to 5 year old who had fever being hospitalized. The researchers prepared 10 images of steps in handling febrile seizures randomly and asked the respondents to arrange the pictures according to their knowledge. The results were observed to determine their knowledge rearranging as pretest data. Afterward, health education was given about 10 correct steps. Thereafter, reobserved was made and the knowledge in arranging 10 images was obtained as post test data. The knowledge score before health education was 20.75% and after was 83.75%. While the analytical test used paired t test. The results showed a significant relationship between knowledge before and after health education. p value = 0.00 < 0.05. The results showed that the value of tcount (14.26) > t table (2.26). Increased knowledge in mothers reduced the risk of recurrence of febrile seizures in toddler and the nurse who had not tought these steps needed to run regularly to the mothers whose child was being hospitalized.


PEDIATRICS ◽  
1978 ◽  
Vol 61 (6) ◽  
pp. 940-940
Author(s):  
Peter Camfield ◽  
Carol Camfield

The riddle of febrile seizures is that despite their high risk of recurrence (35% to 50%), the natural history of the disorder is benign for the vast majority of children.1 If daily phenobarbital administration for several years is to be recommended after the first febrile seizure, it must be shown to be exceedingly effective and safe. The commendable study of Woff et al. is the second2 prospective randomized trial with concurrent controls of the efficacy of phenobarbital to prevent recurrent febrile seizures.


PEDIATRICS ◽  
1953 ◽  
Vol 11 (4) ◽  
pp. 341-357
Author(s):  
WILLIAM G. LENNOX

In a child, a convulsive seizure in association with fever may mean 1 of 6 things. 1. The fever may be a consequence of a spontaneous seizure, the results of an excess of muscular energy and heat. 2. The seizure may be the result of excess hydration or of antibiotics given to combat an infection. 3. The fever may be a seizure phenomenon, the result of a paroxysmal seizure discharge in the region of the hypothalamus. 4. The seizure may be due not to the fever but to bacterial toxins. 5. It may be the secondary result of cerebral pathology induced by an invasion of the brain by the infectious organisms. 6. The seizure may be due to no one of these, but be the direct response of the young child's organism to high fever in association with some infection. In addition, the seizure may not be the consequence of fever, but both fever and seizure a consequence of toxic action on brain cells. Curious features as yet not satisfactorily explained are. 1. Fever-induced seizures belong predominantly to the very young. 2. Almost invariably the febrile seizure, if there is such, is the child's initial seizure. 3. Response to fever is almost invariably a convulsion rather than some other manifestations of epilepsy. A study was made of 1,136 persons whose first convulsive seizure occurred in the first decade of life, 298 having had fever-induced seizures (usually with subsequent non-febrile), 838 having had none. The two groups were compared with respect to age at the first seizure, the presence of antecedent brain pathology, the sex of patients and whether seen in clinic or office. Extreme youth and absence of pathology were most often associated with febrile seizures. Among a total of 407 fever-activated cases, 76.9% subsequently experienced nonfebrile seizures. In 22% an interval of five years or longer separated the last febrile seizure from the first nonfebrile one. With respect to the type of subsequent seizures, an undue proportion of patients had only psychomotor seizures, suggesting that febrile seizures may sometimes be attended by temporal lobe lesions. Febrile seizures are usually innocuous, but if prolonged, focal or attended by much cyanosis or protracted coma, they may cause brain damage. Of 392 patients who sustained brain injury in the first 10 years of life, febrile seizures were blamed for the injury and the continuing epilepsy in 5.4%. Most notable of these findings, however, is the confirmation of what others have reported, that the genetic influence in children having fever-induced seizures is unduly high. In the author's group, this influence, as measured by the incidence of epilepsy among near relatives, is approximately double the genetic influence in young children having only nonfebrile seizures. If we accept the view that evidence of hereditary transmission is the hall-mark of essential epilepsy, then a febrile seizure is epilepsy; but more than that, it is an unusually pure culture of epilepsy. This conclusion has a corollary. Fever-activated epilepsy is short lived. The majority of children with a history of fever-induced seizures have had only one or two. Therefore, the more pure or essential the epilepsy, the better the outlook for spontaneous recovery. Seizures uncomplicated by some acquired pathology of the brain tend to be short lived, perhaps even self-limited—limited by the stabilizing influence of age.


2020 ◽  
Vol 88 (1) ◽  
pp. 44-47
Author(s):  
Sanavio Matteo ◽  
Saladini Marina ◽  
Favretto Donata ◽  
Snenghi Rossella

We present the case of a 60-year-old male, with a long history of epilepsy, who was discovered submerged and unconscious in a small thermal whirlpool bath. The circumstances were forensically reviewed to include examination of clinical data and an autopsy with toxicological analysis. The conclusion was that “warm” hydro-therapy had contributed more than “hot” mud-therapy to the onset of epilepsy which led to accidental drowning, notwithstanding the deceased’s treatment with the long-lasting, poly-drug antiepileptic therapy. Further, we analysed the Italian medical indications of wellness centres for patients with epilepsy or other diseases.


2019 ◽  
Vol 32 (1) ◽  
pp. 39-45
Author(s):  
M Luthfor Rahman ◽  
Belal Hossain ◽  
Belal Uddin ◽  
Sanaul Haq Mia

Introduction: Febrile convulsion is the most common seizure disorder in the pediatric age group. It occurs in 2-5% of children. A febrile seizure is a seizure accompanied by fever (temperature 100.4°F or 38°C by any method), without central nervous system infection, that occurs in infants and children 6 through 60 months of age. Aim: The study was conducted to see the effect of serum sodium level on the recurrence of febrile seizure during the same febrile illness. Materials and Method: A cross-sectional descriptive study which enrolled 65 children admitted with febrile seizures at 100 bed district hospital, Naogaon. They were divided in to two groups, those with a single seizure and the rest were children with more than one seizures. Serum sodium levels were estimated after stabilization of patients. The probability of recurrent febrile seizures and serum sodium level was analyzed. Results: Hyponatremia (serum sodium <135 mmol/l) was seen in 12(18.5%) of 65 children and the remaining 81.5% children had normal serum sodium level (serum sodium 135-145 mmol/l). Among the hyponatremia group all children developed more than one seizure during the same febrile episode. The mean serum sodium level in patients with single and recurrent seizure was 138.48±2.17mmol/l and 135.27±3.11mmol/(P<0.001). The relationship between the probability of a recurrent seizure and serum sodium level is statistically highly significant. Conclusion: Estimation of the seum sodium in children with febrile seizures help in deciding for admission in hospital as well as to predict seizure recurrence within the same febrile episode. TAJ 2019; 32(1): 39-45


2021 ◽  
Vol 9 (08) ◽  
pp. 293-299
Author(s):  
S. Benzahra ◽  
◽  
A. Karara ◽  
H. Nafiaa ◽  
A. Ouanass ◽  
...  

Background: Given the higher incidence of psychotic disorders in patients with epilepsy, several neurologists and psychiatrists have attempted to explain this controversial comorbidity. Thus, several hypotheses have been put forward but no link has been established with certainty until today. Objectives: The aim of our work is to draw up a socio-demographic and psychopathological profile of patients with schizophrenia-epilepsy comorbidity as well as to assess the risk of suicide, the management, the reasons for admission and the length of hospitalization. Methodology: we conducted a retrospective cross-sectional study on medical records of patients with schizophrenia and epilepsy who were hospitalized at the Ar-Razi University Psychiatric Hospital in Salé between January 01, 2017 and March 31, 2021. Results: Our study included 56 patients. The average age was 33 + / - 9.83, 55% male. 50% of patients had attempted suicide in the past and 25% had a history of depressive episode, 41.1% had substance use disorder and 26.8% had a family history of psychosis. 85.7% of our patients developed schizophrenia from pre-existing epilepsy the time to onset of schizophrenia compared to epilepsy was 11.08 years +/- 7.71. The mean age of onset of schizophrenia is 23.3 years with a mean duration of progression of 9.18 years, 55.4% of patients were on monotherapy and 8.9% had resistant schizophrenia on clozapine. The average age of onset of epilepsy is 14.73 years, with generalized epilepsy in 84% of cases. The average length of stay is 42 days. The reasons for admission were as follows: hetero-aggression 78.6%, delusional verbalization 85.7% and suicide attempt 23.2%. The majority of our patients have been treated with atypical antipsychotics: Risperidone 30.4%, Amisulpride 21.4% and Aripiprazole 12.5%. Conclusion: The co-occurrence of schizophrenia epilepsy suggests the existence of possible common etiopathogenic factors. The management of this comorbidity requires a multidisciplinary collaboration between neurologist and psychiatrist, in order to confirm the diagnosis, establish a good therapeutic approach and propose a management algorithm taking into account the two pathologies.


2018 ◽  
Vol 6 (1) ◽  
pp. 46
Author(s):  
Meggeria Dyah Matrika Tito Putri ◽  
Pudjo Wahjudi ◽  
Irma Prasetyowati

Abstract Diabetes Mellitus or diabetes is a chronic metabolic disease disorder caused by pancreas does not produce enough insulin or the body can’t effectively use produced insulin. In pregnant women with a family history of diabetes mellitus, the prevalence of pregnancy with diabetes mellitus is 5.1%. This research aim to determine description of pregnant women condition with diabetes mellitus in RSD dr. Soebandi Jember. This research used descriptive method with case series design. The sample size of 19 pregnant women with diabetes mellitus was selected by total sampling technique. The results showed that the high maternal age (52.6%), low education (89.5%), unemployment or housewife (89.2%), had a genetic 78.9%), BMI overweight (57.9%), glucosuria (89.5%), history of pre-eclampsia (57.9%), low parity (79%), never miscarried (84.2%). Based on the result of the research, it was concluded that maternal education, maternal job, genetic, overweight BMI, glucosuria, and history of pre-eclampsia had an effect towards the occurrence of pregnant women with diabetes mellitus, also maternal age, parity and history of miscarriage had no effect on the occurrence of pregnant women with diabetes mellitus. To raise awareness of the risks of pregnancy with diabetes mellitus can be done with screening for diabetes mellitus.  Keywords: diabetes mellitus, pregnant women, RSD dr. Soebandi.  


2021 ◽  
Vol 7 (3) ◽  
pp. 453-458
Author(s):  
Novi Komala Sari ◽  
Nina Herlina ◽  
Aswan Jhonet

Background : Epilepsy is a neurological disorder which often found in the world and has the highest incidence in children. The most common risk factor of epilepsy is febrile seizure. Febrile seizure refer to a seizure following by high-fever (>38°C) that often found in the age between 6 month – 5 years old. Objective : This study aim to acknowledge the relation between the febrile sizure history and the incidence of epilepsy found in the children of ≤ 5 years old in RSUD Dr. H. Abdul Moeloek  Lampung Province 2018-2019. Methods: This study used an analytic research design with cross sectional approach. The population being used are all pediatric patients in the age of ≤ 5 years which diagnosed with epilepsy in RSUD Dr. H. Abdul Moeloek  Lampung Province. Further, the sample being used in this research are 42 people which obtained from total sampling technique. While the statistic test being used is Chi square test. Results :Tthis study is show that 31 children (73.8%) had a febrile seizure history, and 11 children (26.2%) had not a febrile seizure history. Further, this study found that 8 children (19.0%) had a partial awakening epilepsy, and 34 children (81.0%) had a general awakening epilepsy. The result of chi square examination which is (p value 0.032) showed that there is a relation between the febrile seizure history and the incidence of epilepsy found in children at age of ≤ 5 yearch in RSUD Dr. H. Abdul Moeloek Provinsi Lampung in the year of 2018-2019. Conclusion : There is a relation between febrile seizure history and the incidence of epilepsy found in child.Suggestion : It is recommended to be able to pay attention, add insight about febrile seizures and epilepsy, so that mothers don’t panic and know how to overcome them. Keywords : Febrile Seizure, Epilepsy, Child ABSTRAK Latar Belakang : Epilepsi merupakan kelainan neurologis yang sering ditemui di dunia dan insidensinya terbanyak pada masa anak-anak. Faktor risiko epilepsi yang tersering adalah kejang demam. Kejang demam mengacu pada kejang yang berhubungan dengan demam tingkat tinggi (> 38°C) yang sering terjadi pada usia 6 bulan – 5 tahun.Tujuan Penelitian : Penelitian ini bertujuan untuk mengetahui hubungan riwayat kejang demam dengan kejadian epilepsi pada anak ≤ 5 tahun di RSUD Dr. H. Abdul Moeloek Provinsi Lampung 2018-2019. Metode Penelitian : Penelitian ini menggunakan desain penelitian analitik dengan pendekatan cross sectional. Populasi yang digunakan adalah semua pasien anak usia ≤ 5 tahun yang didiagnosis epilepsi di RSUD Dr. H. Abdul Moeloek Provinsi Lampung. Sampel dalam penelitian ini berjumlah 42 orang yang diambil dengan teknik total sampling. Uji statistik yang digunakan adalah uji Chi Square.Hasil Penelitian : Hasil penelitian ini menunjukkan sebanyak 31 anak (73.8%) memiliki riwayat kejang demam, serta 11 anak (26.2%) tidak memiliki riwayat kejang demam. Dan didapatkan sebanyak 8 anak (19.0%)  memiliki epilepsi bangkitan parsial, serta 34 anak (81.0%) memiliki epilepsi bangkitan umum. Hasil uji Chi Square yaitu (p value 0.032) terdapat hubungan anatara riwayat kejang demam dengan kejadian epilepsi pada anak ≤ 5 tahun di RSUD Dr. H. Abdul Moeloek Provinsi Lampung Tahun 2018-2019.Kesimpulan : Terdapat hubungan antara riwayat kejang demam dengan kejadian epilepsi pada anak.Saran : Disarankan untuk dapat memperhatikan, menambah  wawasan tentang kejang demam dan epilepsi, sehingga ibu tidak panik dan mengetahui cara penanggulangannya. Kata Kunci : Kejang Demam, Epilepsi, Anak.


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