scholarly journals CLINICAL MANIFESTATION AND PATHOGENESIS OF NERVOUS SYSTEM INVOLVEMENT IN SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS-2 INFECTION

2020 ◽  
pp. 23-28
Author(s):  
VALENTINA TJANDRA DEWI ◽  
ANAK AGUNG AYU PUTRI LAKSMIDEWI ◽  
KETUT AYU SUDIARIANI
Keyword(s):  
Nervous System ◽  
Respiratory Failure ◽  
Severe Acute Respiratory Syndrome ◽  
Respiratory Symptoms ◽  
Medical Personnel ◽  
Neurological Manifestations ◽  
Treatment And Prevention ◽  
Global Pandemic ◽  
Organ Systems ◽  
The World

Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) or CoV disease 2019 (COVID-19) infection has spread throughout the world and becomes a global pandemic. Various studies are still ongoing to be able to understand this viral infection in terms of symptomatology, transmission, pathogenesis, its treatment, and prevention. In addition to respiratory symptoms that are commonly reported in SARS-CoV-2 infections, there are many reports of symptoms appearing in other organ systems with one of them being neurological manifestation. The neurological manifestations involve not only the central and peripheral nervous systems but also there was also a suspicion that the potential invasion of SARS-CoV-2 in the nervous system might be able to take part in the occurrence of respiratory failure that is found in patients with COVID-19. The continuity of the study and the awareness of medical personnel from various fields of science must be increased to fight against the COVID-19 pandemic and ensuring optimal treatment for patients.

scholarly journals COVID-19-Induced Hyperleucocytosis in Chronic Lymphocytic Leukaemia

2021 ◽  
Author(s):  
Balraj Singh ◽  
Sarah Ayad ◽  
Parminder Kaur ◽  
Ro-Jay Reid ◽  
Sachin Gupta ◽  
...  
Keyword(s):  
Severe Acute Respiratory Syndrome ◽  
Chronic Lymphocytic Leukaemia ◽  
Respiratory Symptoms ◽  
Lymphocytic Leukaemia ◽  
Wide Spectrum ◽  
Multiple Organ ◽  
Global Pandemic ◽  
Organ Systems ◽  
Wbc Count ◽  
Novel Coronavirus

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a novel coronavirus responsible for the current global pandemic, coronavirus disease 2019 (COVID-19). COVID-19 usually presents with respiratory symptoms but can affect multiple organ systems. A wide spectrum of complications can occur depending upon the comorbidities of patients. There is limited literature available regarding the presentation and outcome of COVID-19 in chronic lymphocytic leukaemia (CLL) patients. We report 2 cases of COVID-19-induced hyperleucocytosis (WBC count >100,000/?l) in CLL patients.

scholarly journals SARS-CoV-2 Infection and Guillain-Barré Syndrome: A Review on Potential Pathogenic Mechanisms

2021 ◽  
Vol 12 ◽  
Author(s):  
Shahrzad Shoraka ◽  
Maria Lucia Brito Ferreira ◽  
Seyed Reza Mohebbi ◽  
Amir Ghaemi
Keyword(s):  
Severe Acute Respiratory Syndrome ◽  
Respiratory System ◽  
Respiratory Symptoms ◽  
Guillain Barre Syndrome ◽  
New Disease ◽  
Neurological Manifestations ◽  
Pathogenic Mechanisms ◽  
The World ◽  
Guillain Barré Syndrome ◽  
Guillain Barré

Since December 2019, the world has been facing an outbreak of a new disease called coronavirus disease 2019 (COVID-19). The COVID-19 pandemic is caused by a novel beta-coronavirus named severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The SARS-CoV-2 infection mainly affects the respiratory system. Recently, there have been some reports of extra-respiratory symptoms such as neurological manifestations in COVID-19. According to the increasing reports of Guillain-Barré syndrome following COVID-19, we mainly focused on SARS-CoV-2 infection and Guillain-Barré syndrome in this review. We tried to explain the possibility of a relationship between SARS-CoV-2 infection and Guillain-Barré syndrome and potential pathogenic mechanisms based on current and past knowledge.

scholarly journals PREVALANCE OF NEUROLOGICAL MANIFESTATIONS IN PATIENT WITH COVID-19 INFECTION

2021 ◽  
pp. 29-31
Author(s):  
R.Shanthi Malar ◽  
Govindarajulu Govindarajulu ◽  
N.Thamilpavai Arulnambi ◽  
S. Gopal
Keyword(s):  
Nervous System ◽  
Respiratory Symptoms ◽  
Cross Sectional Study ◽  
Neurological Manifestations ◽  
Sectional Study ◽  
Cross Sectional ◽  
Medical College ◽  
Global Pandemic ◽  
The Central Nervous System ◽  
Symptoms And Signs

BACKGROUND: Covid 19 has caused a global pandemic since November 2019. Neurological manifestations also occur in addition to respiratory symptoms and distress. Recently it has been found that the neurological symptoms of covid 19 are also common. OBJECTIVE: To study the neurological manifestations of patients with covid 19 MATERIALS AND METHODS: In this cross sectional study design, patients admitted in GOVT Kilpauk Medical College ,Chennai with symptoms and signs of Covid 19 infection with laboratory confirmed / CT with informed consent. Neurological examination done by trained neurologist and symptoms were analysed into those involving the central nervous system and peripheral nervous system RESULTS: Of 349 patients mean SD age,55.14[14.06]; 232 males [66%] with COVID 19 and 117 females [33%], Of 349 patients ,covid positive patients 179 [51.3%] ,covid negative 170 [48.7 %] .The most common symptoms of patients are giddiness 282[ 80.8%], weakness of limbs 312[ 89%], myalgia 91 [26%], bells palsy 67 [19%], ataxia 57 [16.3%], seizures 54 [15%] ,loss of taste 37 [10.6%] ,loss of smell 12 [3.4%] ,neck rigidity 10 [2.8%] . The mortality rate of patients ,covid positive with pneumonia 98 cases [58.3%], covid negative 70 [ 41.7%]. CONCLUSION : Patients with covid -19 commonly have neurological manifestations .

scholarly journals Acute Ischemic Colitis in a Covid-19 Patient

2021 ◽  
Vol 4 (1) ◽  
pp. 60-65
Author(s):  
Urciuoli L ◽  
Guerriero E
Keyword(s):  
Gastrointestinal Tract ◽  
Severe Acute Respiratory Syndrome ◽  
Ischemic Colitis ◽  
Respiratory Symptoms ◽  
World Health ◽  
Pulmonary System ◽  
Global Pandemic ◽  
Initial Symptoms ◽  
The World ◽  
Health Organization

Coronavirus disease 2019 (COVID-19) is caused by a novel strain of coronavirus called severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which was first discovered in Wuhan, China, in December 2019. The virus has quickly spread around the globe and has been declared a global pandemic by the World Health Organization. Although in COVID-19 respiratory symptoms predominate, there is a relevant body of evidence that initial symptoms and complications of COVID-19 are not limited to the pulmonary system, but can involve also the gastrointestinal tract. We report a case that presented with ischemic colitis in the setting of PCR-confirmed SARS-CoV-2 infection.

scholarly journals Neurological manifestations of COVID-19: a clinical approach

2021 ◽  
Author(s):  
Ni Made Susilawathi ◽  
Kumara Tini ◽  
Ida Ayu Sri Wijayanti ◽  
Putu Lohita Rahmawati ◽  
Dewa Putu Wisnu Wardhana ◽  
...  
Keyword(s):  
Nervous System ◽  
World Health ◽  
Critical Conditions ◽  
Clinical Approach ◽  
Vascular Endothelial ◽  
Neurological Manifestations ◽  
Global Pandemic ◽  
The World ◽  
Health Organization ◽  
Human Nervous System

Coronavirus disease 2019 (COVID-19) is an emerging infectious disease caused by SARS-CoV-2 which attacks the respiratory tract and has been declared a global pandemic by the World Health Organization. The disease has a very wide clinical spectrum which can be manifested as asymptomatic to critical conditions. SARS-CoV-2 shows a neurotropism proven by its identification in the cerebrospinal fluid and brain vascular endothelial. The complete mechanism of how the virus invades the human nervous system is yet to be identified. Thus, every neurologist needs to follow the progressivity of COVID-19 symptoms involving the nervous system.

Neurological Involvement of Patients with COVID-19: Proposed Neuroinvasive Mechanisms and Management

2020 ◽  
Vol 24 (4) ◽  
Author(s):  
Nahid Davoodian ◽  
Maryam Arab Firouzjaei ◽  
Ahmadagha Negahi
Keyword(s):  
Nervous System ◽  
Organ Failure ◽  
Present Article ◽  
Respiratory Symptoms ◽  
Neurological Symptoms ◽  
Neurological Involvement ◽  
The Novel ◽  
Neurological Manifestations ◽  
The World ◽  
Novel Coronavirus

: The novel Coronavirus Disease 2019 (COVID-19) is a highly contagious virus that has caused tremendous chaos in the world. Generally, respiratory symptoms are dominant manifestations in patients with COVID-19. However, the involvement of other organs, such as the nervous system has also been reported, which elucidates the capability of the virus to induce multi-organ failure. In this regard, the presentation of neurological symptoms in infected patients has raised the concern regarding the neuroinvasive potential of COVID-19. As of today, there is emerging evidence that supports the susceptibility of the nervous system to COVID-19. Undoubtedly, the awareness of these findings can result in the timely management and treatment of patients. In the present article, we documented a brief overview of neurological manifestations, possible neuroinvasion mechanisms of COVID-19, and the management of neurological symptoms in infected patients.

Overview of COVID-19 and neurological complications

2021 ◽  
Vol 0 (0) ◽  
Author(s):  
Nasrin Hosseini ◽  
Shabnam Nadjafi ◽  
Behnaz Ashtary
Keyword(s):  
Nervous System ◽  
Severe Acute Respiratory Syndrome ◽  
Cranial Nerve ◽  
Virus Disease ◽  
Neurological Complications ◽  
The Body ◽  
Neurological Manifestations ◽  
Wide Range ◽  
The World ◽  
Symptoms And Signs

Abstract The sudden and storming onset of coronavirus 2 infection (severe acute respiratory syndrome coronavirus 2 [SARS-CoV-2]) was associated by severe acute respiratory syndrome. Recently, corona virus disease 19 (COVID-19) has appeared as a pandemic throughout the world. The mutational nature of the virus, along with the different means of entering and spreading throughout the body has involved different organs. Thus, patients are faced with a wide range of symptoms and signs. Neurological symptoms, such as anosmia, agnosia, stroke, paralysis, cranial nerve deficits, encephalopathy, meningitis, delirium and seizures, are reported as common complications affecting the course of the disease and its treatment. In this review, special attention was paid to reports that addressed the acute or chronic neurological manifestations in COVID-19 patients who may present acute respiratory syndrome or not. Moreover, we discussed the central (CNS) and peripheral nervous system (PNS) complications in SARS-Cov2-infected patients, and also the pathophysiology of neurological abnormalities in COVID-19.

The relevance of dietetic approach of Ayurveda from the perspective of COVID-19 pandemic

2020 ◽  
Vol 11 (SPL1) ◽  
pp. 748-752
Author(s):  
Swapnali Khabade ◽  
Bharat Rathi ◽  
Renu Rathi
Keyword(s):  
Severe Acute Respiratory Syndrome ◽  
Healthy Person ◽  
World Health ◽  
Physical And Mental Health ◽  
Leading Role ◽  
Global Pandemic ◽  
The People ◽  
The World ◽  
Health Organization ◽  
The Individual

A novel, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), causes severe acute respiratory syndrome and spread globally from Wuhan, China. In March 2020 the World Health Organization declared the SARS-Cov-2 virus as a COVID- 19, a global pandemic. This pandemic happened to be followed by some restrictions, and specially lockdown playing the leading role for the people to get disassociated with their personal and social schedules. And now the food is the most necessary thing to take care of. It seems the new challenge for the individual is self-isolation to maintain themselves on the health basis and fight against the pandemic situation by boosting their immunity. Food organised by proper diet may maintain the physical and mental health of the individual. Ayurveda aims to promote and preserve the health, strength and the longevity of the healthy person and to cure the disease by properly channelling with and without Ahara. In Ayurveda, diet (Ahara) is considered as one of the critical pillars of life, and Langhana plays an important role too. This article will review the relevance of dietetic approach described in Ayurveda with and without food (Asthavidhi visheshaytana & Lanhgan) during COVID-19 like a pandemic.

scholarly journals Neurological Manifestations of COVID-19 patients: An Updated Review and Observations of COVID Patients in the National Institute of Neurosciences and Hospital, Dhaka, Bangladesh

2020 ◽  
pp. 122-132
Author(s):  
Mohammad Enayet Hussain ◽  
Md Azharul Hoque ◽  
Md Badrul Alam ◽  
Md Abdullah Yusuf ◽  
Rajib Nayan Chowdhury ◽  
...  
Keyword(s):  
Nervous System ◽  
Severe Acute Respiratory Syndrome ◽  
Viral Infection ◽  
Clinical Manifestation ◽  
Early Experience ◽  
Neurological Manifestations ◽  
Recent Outbreak ◽  
Near Future

Involvement of the nervous system after viral infection is common. Certain viruses show neurotropism. Recent outbreak of severe acute respiratory syndrome CoV 2 (SARSCov- 2) virus has also exhibited neurotropic properties with various neurological manifestations. The pathophysiology of their neurotropism is not yet clearly known. The details of pathophysiology, clinical manifestation and management are expected to be explored in the near future. Here we review the Neurological manifestations of COVID-19 and the early experience in the National Institute of Neurosciences and Hospital. J Bangladesh Coll Phys Surg 2020; 38(0): 122-132

scholarly journals Research on the Neurobiology of COVID-19

2021 ◽  
Vol 245 ◽  
pp. 03045
Author(s):  
Yilun Tong
Keyword(s):  
Nervous System ◽  
Molecular Mechanism ◽  
The Novel ◽  
Neurologic Manifestations ◽  
Neurological Manifestations ◽  
Corona Virus ◽  
The World ◽  
Human Nervous System ◽  
Different Parts

More studies have shown the neurological manifestations of the novel corona virus (COVID-19) and have inferred the molecular mechanism by which it invades the nervous system. The neurological aspect of the COVID-19 pandemic has been differently interpreted and dealt with in different parts of the world. To review the neurological manifestations and the neurovirulent mechanism by which CoV attacks the human nervous system and to examine different perspectives on this very same topic, the research on PubMed and ScienceDirect is conducted. The mechanisms that CoV enter and attack the nervous system and the subsequent neurologic manifestations have been proposed and now seems quite clear. However, more studies have to be done directly on the effect of COVID-19 on the CNS as well as the PNS.

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