scholarly journals Odontogenic keratocysts: a 22-year epidemiological study and case report

2019 ◽  
Vol 60 (2) ◽  
pp. 43-52
Author(s):  
Fernanda Chiguti Yamashita ◽  
Gustavo Nascimento de Souza Pinto ◽  
Elen De Souza Tolentino ◽  
Mariliani Chicarelli ◽  
Liogi Iwaki Filho ◽  
...  

Odontogenic Keratocyst (OKC) is a cyst that presents local aggression and a high recurrence; thus, a better understanding of its clinical characteristics and treatment options is required. The aim of this study is to report a case and describe the epidemiology and characteristics of OKCs diagnosed at a referral service for patients with oral lesions. Patients with histopathological diagnosis of OKC were included in the sample over 22 years. The study highlights the demographic and clinical-radiological characteristics, as well as the treatment options. In addition, a case of an extensive OKC in the mandible is reported. 3064 medical records were analyzed and 16 cases of OKC (0.52%) were found, with two recurrences (12.5%). The mean age of the patients was 33.19 years, being the third decade of life more affected (31.25%), with equal prevalence for both sexes. The mandible was more affected (68.75%), mainly its body. The differential diagnosis included the dentigerous cyst (11.54%) and the ameloblastoma (11.54%). The most frequent treatment was the curettage enucleation (50%). In the reported case, enucleation associated with cryotherapy was performed, followed by rehabilitation with xenogen graft and osseointegrated implant. OKC presents a wide spectrum of differential diagnoses due to its non-specific clinical-radiographic characteristics. The case reported shows that treatments such as enucleation may be efficient when accompanied by adjuvant techniques.

2021 ◽  
Vol 62 (1) ◽  
pp. 56-62
Author(s):  
Bruna Luísa Neumann ◽  
Stéfanie Thieme ◽  
Amanda De Farias Gabriel ◽  
Virgilio Gonzales Zanella ◽  
Felipe Martins Silveira ◽  
...  

Introduction: odontogenic lesions (OLs) represent a heterogeneous group of oral and maxillofacial pathologies presenting distinct characteristics. The present study aimed to identify the clinical and pathological characteristics of OLs diagnosed in a southern Brazilian hospital. Materials and methods: a retrospective study was performed to evaluate cases with histopathological diagnosis of OLs identified in the period between 2007 and 2017. The patient's medical records were evaluated in order to obtain the clinical and pathological characteristics and the histopathological diagnosis from each case. Results: a total of 255 cases of OLs were identified. From these, 197 (77%) odontogenic cysts and 58 (23%) odontogenic tumors were surveyed, with only one case (0,39%) of a malignant odontogenic neoplasm. The most prevalent diagnosis were radicular cyst (32.5%) and dentigerous cyst (31.76%), followed by odontogenic keratocyst (10.98%), odontoma (10%) and ameloblastoma (10%). The majority of the cases affected the mandible (53.7%) with a slight preference by female individuals (51%). The mean age was 34±20.53 years old. Discussion: the presented data are in accordance with the literature regarding the rarity of the diagnosis of odontogenic tumors. Conclusion: the present study demonstrated the main clinical and pathological characteristics of OLs diagnosed in a southern Brazilian hospital, contributing to a better understanding of these injuries profiles.


2002 ◽  
Vol 26 (4) ◽  
pp. 413-418 ◽  
Author(s):  
Fabrício Bitu Sousa ◽  
Adriana Etges ◽  
Luciana Corrêa ◽  
Ricardo Alves Mesquita ◽  
Ney Soares de Araújo

There are few studies on pediatric oral pathologies in the literature. This study presents data from a review of 2,356 biopsies of young patients (birth to 14 years) received over 15 years (1985-2000) in the Oral Pathology Service at the University of Sao Paulo, Brazil. Information about patients (sex, age, race) and histopathological diagnosis was retrieved. Diagnosis data of 2,356 biopsies were classified into 20 groups.There was no significant difference between male (50.0%) and female (49.0%) patients. White is the predominant race (69.0%), and patients ages were concentrated between 9 and 14 years old (70%). Mucocele was the most frequent (13.5%), followed by dentigerous cyst (6.5%) and fibrous hyperplasia (5.4%). Papilloma and Langerhans cells histiocytosis were the most common non-odontogenic benign and malignant tumors, respectively. In the group of odontogenic tumors, odontoma was the most frequent, and ameloblastoma had a significant incidence (27 cases). These data are important in order to detect differences in geographic areas, diagnosis line tendencies and for clinicians to perform judgment to evaluate of the pediatric patients before the biopsy and management of pediatric oral lesions.


Author(s):  
Sangeeta Gahlot ◽  
Surendra Yadav ◽  
Makkhan Lal Saini

Background: In this study, epidemiological profiles of COVID-19 patients who have visited the hospital have been evaluated. Methods: We collected data of 100 patients from their medical records. These data included age, sex, comorbidities, levels of illness severity (mild, moderate, severe, and asymptomatic), signs and symptoms, treatment options, laboratory findings, and computed tomography (CT) images Results: The mean age were 61.23±12.36 years with age groups ranging from 17 to 85 years. Men were 69; M:F ratio being 2.26:1. There were 76 symptomatic and 24 asymptomatic patients. Mortality was higher in symptomatic patients. Conclusion: Patients aged more than 60 years are more prone for severe disease with Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) pneumonia and this subset of patients requires urgent medical attention. Keywords: Age, Sex, COVID-19.


2019 ◽  
Author(s):  
Ruihua Xu ◽  
Wei Wang ◽  
Bo Zhu ◽  
Xiaoyan Lin ◽  
Dong Ma ◽  
...  

Abstract Background: Colorectal cancer (CRC) is the third most prevalent cancer in China but few large-scale studies were conducted to understand CRC patients. The current study is aimed to gain a real-world perspectives of CRC patients in China. Methods: Using electronic medical records of sampled patients between 2011 and 2016 from 12 hospitals in China, a retrospective cohort study was conducted to describe demographics and disease prognosis of CRC patients, and examine treatment sequences among metastatic CRC (mCRC) patients. Descriptive, comparative and survival analyses were conducted. Results: Among mCRC patients (3,878/8,136, 48%), the fluorouracil, leucovorin, and oxaliplatin (FOLFOX) and other oxaliplatin-based regimens were the most widely-used first-line treatment (42%). Fluorouracil, leucovorin, irinotecan (FOLFIRI) and other irinotecan-based regimens dominated the second-line (40%). There was no a dominated regimen for the third-line. The proportion of patients receiving chemotherapy with targeted biologics increased from less than 20% for the first- and second- lines to 34% for the third-line (p<0.001). The most common sequence from first- to second-line was from FOLFOX and other oxaliplatin-based regimens to FOLFIRI and other irinotecan-based regimens (286/1,200, 24%). Conclusions: Our findings reflected a lack of consensus on the choice of third-line therapy and limited available options in China. It is evident o continue promoting early CRC diagnosis and to increase the accessibility of treatment options for mCRC patients. As the only nationwide large-scale study among CRC and mCRC patients before more biologics became available in China, our results can also be used as the baseline to assess treatment pattern changes before and after more third-line treatment were approved and covered into the National Health Insurance Plan in China between 2017 - 2018.


2020 ◽  
Author(s):  
Ruihua Xu ◽  
Wei Wang ◽  
Bo Zhu ◽  
Xiaoyan Lin ◽  
Dong Ma ◽  
...  

Abstract Background: Colorectal cancer (CRC) is the third most prevalent cancer in China but few large-scale studies were conducted to understand CRC patients. The current study is aimed to gain a real-world perspectives of CRC patients in China. Methods: Using electronic medical records of sampled patients between 2011 and 2016 from 12 hospitals in China, a retrospective cohort study was conducted to describe demographics and disease prognosis of CRC patients, and examine treatment sequences among metastatic CRC (mCRC) patients. Descriptive, comparative and survival analyses were conducted. Results: Among mCRC patients (3,878/8,136, 48%), the fluorouracil, leucovorin, and oxaliplatin (FOLFOX) and other oxaliplatin-based regimens were the most widely-used first-line treatment (42%). Fluorouracil, leucovorin, irinotecan (FOLFIRI) and other irinotecan-based regimens dominated the second-line (40%). There was no a dominated regimen for the third-line. The proportion of patients receiving chemotherapy with targeted biologics increased from less than 20% for the first- and second- lines to 34% for the third-line (p<0.001). The most common sequence from first- to second-line was from FOLFOX and other oxaliplatin-based regimens to FOLFIRI and other irinotecan-based regimens (286/1,200, 24%).Conclusions: Our findings reflected a lack of consensus on the choice of third-line therapy and limited available options in China. It is evident o continue promoting early CRC diagnosis and to increase the accessibility of treatment options for mCRC patients. As the only nationwide large-scale study among CRC and mCRC patients before more biologics became available in China, our results can also be used as the baseline to assess treatment pattern changes before and after more third-line treatment were approved and covered into the National Health Insurance Plan in China between 2017 - 2018.


Bionatura ◽  
2021 ◽  
Vol 6 (2) ◽  
pp. 1845-1850
Author(s):  
Mario Hernández ◽  
Emilio Fors ◽  
Fresia Massuht ◽  
Ingrid Figueredo ◽  
Raúl Caballero ◽  
...  

We retrospectively analyzed the data of 38 hemodialysis patients with COVID-19, including demographic and clinical characteristics were collected from the medical records of patients from Reynadial center from April to June 2020. Of 125 patients from the clinic, 38 (30.4%) were diagnosed with COVID-19. The third part of patients (12) died, the mortality rate was 31%. The mean (±SD) age of the patients was 61±13 years, 57.9% were men. The most common symptoms were shortness of breath and cough; 80% of patients had fever on admission, and more than 90% had hypertension. No significant differences were observed between survivors and non-survivors in demographic and epidemiological characteristics except for gender. We found statistically significant differences between blood pressure and weight before and after the infection by COVID-19. We found a high COVID-19 prevalence in our hemodialysis patients and a high rate of deaths among them, with non-significant statistical differences between survivors and non-survivors of the disease regarding most of the variables studied.


2018 ◽  
Vol 66 (1) ◽  
pp. 42-49
Author(s):  
Rani Iani Costa GONÇALO ◽  
Mara Luana Batista SEVERO ◽  
Ana Miryam Costa de MEDEIROS ◽  
Patrícia Teixeira de OLIVEIRA ◽  
Éricka Janine Dantas Da SILVEIRA

ABSTRACT Objective: To conduct a retrospective study on a series of cases of PV and BMMP with manifestations in the oral cavity in order to ascertain prevalence, sociodemographic characteristics, diagnostic maneuvers, treatment and follow-up. Methods: This is a retrospective, descriptive study in which clinical data were collected from the medical records of all cases of PV and BMMP registered and diagnosed, between 1995 and 2015, in the Oral Diagnostic Service of the UFRN Department of Dentistry. Results: The mean age of the total sample (n = 36) was 41.64, with females the most frequent (n = 26; 72.22%) and the cheek mucosa being the site most affected (n = 20; 27.40%). Eight patients (22.22%), including 5 cases of PV and 3 BMMP, were clinically reevaluated. All patients exhibited lesions at the time of follow-up. Prednisone (n=7; 87.5%) and clobetasol propionate (n=8, 100%) were the most widely used drugs in the systemic and topical treatment, respectively. The follow-up period ranged from 5 months to 5 years. Conclusion: The clinical profile of patients in this study was similar to that evidenced in the literature. However, it was found that the oral lesions were more resistant to the treatment used on the patients evaluated.


2015 ◽  
Vol 8 (2) ◽  
pp. 93
Author(s):  
Juniar Siregar

This study presents a research report on improving students’ Learning results on IPA through Video. The objective was to find out whether students’ learning result improved when they are taught by using Video. It was conducted using classroom action research method. The subject of the study was the Grade IV students of SDN 187/IV Kota Jambi which is located on Jln. Adi Sucipto RT 05 Kecamatan Jambi Selatan, and the number of the students were 21 persons. The instruments used were test. In analyzing the data, the mean of the students’ score for the on fisrt sycle was 65,4 (42,85%) and the mean on cycle two was 68,5 (37,15%) and the mean of the third cycle was 81,4 (100%). Then it can be concluded that the use of video on learning IPA can improve the students’ learning result. It is suggested that teachers should use video as one of the media to improve students’ learning result on IPA.Keywords : IPA, students’ learning result, video


Author(s):  
Hotria Manik ◽  
Elia Masa Ginting

This study attempts to improve students’ writing achievement in recount text through Think-Pair-Share Strategy. This study was conducted by using classroom action research. The subject of the research was class VIII-1 SMPN 1 Pematangsiantar. The number of the students was 32 students, consisted of 5 males and twenty seven females. The research was conducted in two cycles and consisted of six meetings. The instruments for collecting data were writing tests as the quantitative data and diary notes, observation sheet, interview sheet and questionnaire sheet as qualitative data. Based on the writing score, students’ scores kept improving in every test. In analyzing the data, the mean of the students’ score for the first test as a pre-test was 57.84, for the second test as a post test I was 73.56, for the third test as a post test II was 77.56. Based on diary notes, observation sheet and questionnaire sheet, it was found that students were actively involved in writing process. The result of the research showed that Think-Pair-Share Strategy can improve students’ achievement in writing recount text.   Keywords: Think Pair Share, Writing, Recount text, Action research


Author(s):  
Esra N.F. Hutahaean And Tjut Ernidawati

This research concerns on improving students’ writing achievement in the report text through film.  The objective was to find out the improvement of students’ writing achievement in writing the report text through film. This research was conducted by using action research method. The subject of the research was XI IPA grade students of SMA SWASWTA JOSUA Medan. The numbers of students were thirty one students. They were taught writing the report text through film. The instruments used were writing report text test, diary notes, interview sheets, questionnaire sheets and observation sheets. In analyzing data, the mean of students’ score for the first competency test was 43.1, for the second competency test was 64.8 and for the third competency test was 76.3 and the total percentage of improvement from the first competency test to the third competency test was 84.1%. The conclusion is that through watching film can improve the students’ writing achievement in the report text. It is suggested that teachers should apply watching film as one of media to improve students’ writing achievement in the report text.


Sign in / Sign up

Export Citation Format

Share Document