scholarly journals Erectile dysfunction in young men

2021 ◽  
Author(s):  
Dr. Carolina Diamandis ◽  
Steven Smith ◽  
Adrian Tudor ◽  
David Seideman
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Erectile Dysfunction ◽  
Sexual Arousal ◽  
Health Problem ◽  
Young Men ◽  
Negative Effects ◽  
The Central Nervous System

Erectile dysfunction (ED) is what physicians call the inadequate or absent stiffening of the penis despite emotional sexual arousal. More and more men are suffering from such erectile issues. The better we understand the involvement of the central nervous system in various sexual functions, the more we will also understand its determining role in these disorders. Erectile dysfunction are an increasing health problem because of the aging of the population and new effects through readily available pornography (negative effects of chronic over-stimulation) which have an impact on young men.

scholarly journals Markers of success of passing the unified state exam

2019 ◽  
Vol 70 ◽  
pp. 09010
Author(s):  
Lubov Gubareva ◽  
Yulia Konygeva
Keyword(s):  
High School ◽  
Gender Differences ◽  
Central Nervous System ◽  
Nervous System ◽  
Secondary School ◽  
Young Women ◽  
Young Men ◽  
Verbal Aggression ◽  
Indirect Aggression ◽  
The Central Nervous System

102 schoolchildren of the 9-11th classes of secondary school No. 2 of Stavropol, without genetic pathology, were examined. The functional state of the central nervous system was determined by the method of computer chronoreflexometry; using psychological tests, we determined the level of personality (PA) and situational (SA) anxiety, as well as (and) the level of aggressiveness. It was established that in the 9-11th classes, girls and young women have a higher level of PA and SA than boys and young men (p <0.050.01). During the training the girls’ and boys’ the level of PA remains relatively constant, however, the variability of PA of 17 years-old young women is higher than of the young men. The level of SA of the girls tends to increase throughout the entire period of study in high school, while for boys it rises only the 10th class, and decreases by the beginning of the 11th class. For the indicators of aggression, gender differences begin to appear in the 10th class: aggressiveness index and indirect aggression in the boys’ significantly higher than the girls’ are. In the 11th class, young men significantly increase in comparison with girls an indicator of hostility, verbal aggression and offence (p <0.05).

scholarly journals Morbidity in newborns exposed to organophosphorus pesticides

2010 ◽  
Vol 63 (5-6) ◽  
pp. 414-417
Author(s):  
Momcilo Djordjevic ◽  
Predrag Sazdanovic ◽  
Gordana Djordjevic ◽  
Bozidar Jovanovic
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Breast Milk ◽  
Cholinesterase Inhibitors ◽  
Organophosphorus Pesticides ◽  
Control Group ◽  
Negative Effects ◽  
The Third ◽  
The Central Nervous System ◽  
Activity Mechanism

Introduction. Insecticides are toxines by which we destroy harmful insects. The most frequent insecticides which are used today are organophosphorus pesticides. This group of compounds make substances whose activity mechanism is based on the inhibition of acetylcho?linesterase in nerve synapsis, thus producing holynergic syndrome, resulting from the accumulation of acetylcholine which developed due to the absence of decomposition under the influence of cholinesterase. In the clinical picture of acute toxication by cholinesterase inhibitors there is a clear difference between muscarinic and nicotine effects. The basic aim of the study was to establish the effects of organophosphorus pesticides present in blood and breast milk of mothers on newborns morbidity. Material and methods. The study group consisted of 18 newborns whose mothers had isolated organophosphorus pesticides in their blood and breast?milk on the third day after delivery, and the control group consisted of 84 newborns whose mothers did not have isolated organophosphorus pesticides in their blood and breastmilk. Results. Morbidity is three times greater, often in combination with some disorders of the central nervous system, and the relative risk for its appearance is eight time greater in newborns exposed to organophosphorus pesticides. Disscusion. Disorders that appear in newborns exposed to pesticides are mutagenic, cancerogenic and neurotoxic and some agenses could disturb the immune system which is reflected in morbidity increase, primarly of the central nervous system. Conclusion. The presence of organophosphorus pesticides in blood and breast milk has negative effects on newborns. In addition to acetylcho?linesterase inhibition, organophosphorus pesticides react by means of other mechanisms as well.

scholarly journals EFEK APOMORFIN SUBLINGUAL PADA EREKSI PENIS

2013 ◽  
Vol 4 (3) ◽  
Author(s):  
Kaleb D.S. Salossa ◽  
Sonny J.R. Kalangi ◽  
Ghazaly Adam
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Erectile Dysfunction ◽  
Cardiovascular Diseases ◽  
Paraventricular Nucleus ◽  
Penile Erection ◽  
Sexual Stimulation ◽  
Psychosocial Therapy ◽  
Penile Erections ◽  
The Central Nervous System

Abstract: Erectile dysfunction is the disability of a male to maintain consistant or repeated penile erections sufficiently for successful sexual intercourse. Many efforts have been done to handle this condition, so far. The psychosocial therapy and several medications inter alia: testosterone, yohimbine, trazadone, direct intracavernosus injection of alprostadil, penile implantation, and  sildenafil citrate, are not always suitable for the patients’ needs, especiallly those who suffer from cardiovascular diseases. Therefore, a new erectogenic agent has been introduced, the sublingual apomorphine. This apomorphine has a dopamine-like molecule that acts on the dopamine receptors in the paraventricular nucleus (PVN) of the central nervous system to increase the penile erection due to sexual stimulation (erotic imagination, audiovisual, or tactile). The sublingual apomorphine has been proved effective in overcoming the erectile dysfunction, especially the mild and moderate forms. Keywords: penile erection, sublingual apomorphin.     Abstrak: Telah banyak upaya dilakukan untuk mengatasi disfungsi ereksi yang merupakan ketidakmampuan seorang laki-laki secara konsisten atau berulang untuk mencapai dan mempertahankan ereksi penis yang cukup untuk melakukan hubungan seksual. Terapi psikososial dan pengobatan yang pernah diajukan seperti pemberian hormon testosteron, yohimbin, trazadon, injeksi langsung alprostadil intrakavernosa, implantasi penis serta sildenafil sitrat tidaklah selalu sesuai dengan kebutuhan penderita, khususnya penderita disfungsi ereksi dengan penyakit kardiovaskuler. Para ahli berusaha melakukan terobosan baru salah satunya adalah apomorfin sublingual yang merupakan agen erektogenik baru. Apomorfin adalah suatu molekul mirip dopamin yang bekerja pada reseptor dopamin pada paraventricular nucleus (PVN) di sistem saraf pusat untuk meningkatkan rangsangan erektil saat stimulasi seksual (imaginasi erotik, audiovisual dan perabaan) terjadi. Apomorfin sublingual terbukti efektif untuk mengatasi disfungsi ereksi, terutama disfungsi ereksi ringan dan sedang. Kata kunci: ereksi penis, apomorfin sublingual.

scholarly journals Toxicity of metallic nanoparticles in the central nervous system

2019 ◽  
Vol 8 (1) ◽  
pp. 175-200 ◽  
Author(s):  
Krzysztof Sawicki ◽  
Magdalena Czajka ◽  
Magdalena Matysiak-Kucharek ◽  
Berta Fal ◽  
Bartłomiej Drop ◽  
...  
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Metallic Nanoparticles ◽  
Current Knowledge ◽  
Negative Effects ◽  
Scientific Publications ◽  
The Central Nervous System ◽  
The Impact

Abstract Metallic nanoparticles due to their small size and unique physico-chemical characteristics have found excellent applications in various branches of industry and medicine. Therefore, for many years a growing interest has been observed among the scientific community in the improvement of our understanding of the impact of nanoparticles on the living organisms, especially on humans. Considering the delicate structure of the central nervous systemit is one of the organs most vulnerable to the adverse effects of metallic nanoparticles. For that reason, it is important to identify the modes of exposure and understand the mechanisms of the effect of nanoparticles on neuronal tissue. In this review, an attempt is undertaken to present current knowledge about metallic nanoparticles neurotoxicity based on the selected scientific publications. The route of entry of nanoparticles is described, as well as their distribution, penetration through the cell membrane and the blood-brain barrier. In addition, a study on the neurotoxicity in vitro and in vivo is presented, as well as some of the mechanisms that may be responsible for the negative effects of metallic nanoparticles on the central nervous system. Graphical abstract: This review summarizes the current knowledge on the toxicity of metallic NPs in the brain and central nervous system of the higher vertebrates.

Beyond Erectile Dysfunction: Understanding PDE5 Activity In The Central Nervous System

2014 ◽  
pp. 223-246
Author(s):  
Eva P.P. Bollen ◽  
Kris Rutten ◽  
Olga A.H. Reneerkens ◽  
Harry W.M. Steinbusch ◽  
Jos Prickaerts
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Erectile Dysfunction ◽  
The Central Nervous System

scholarly journals Space–brain: The negative effects of space exposure on the central nervous system

2018 ◽  
Vol 9 (1) ◽  
pp. 9 ◽  
Author(s):  
CharlesL Limoli ◽  
Rahul Jandial ◽  
Reid Hoshide ◽  
JDawn Waters
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Negative Effects ◽  
The Central Nervous System

scholarly journals EVALUATION OF THE AEROGENIC IMPACT OF PRIORITY CHEMICAL FACTORS ON THE HEALTH OF THE CHILD POPULATION IN THE ZONE OF THE EXPOSURE OF ALUMINUM ENTERPRISES

2019 ◽  
Vol 98 (1) ◽  
pp. 68-75 ◽  
Author(s):  
N. V. Zaitseva ◽  
Marina A. Zemlianova ◽  
Yu. V. Koldibekova ◽  
I. G. Zhdanova-Zaplesvichko ◽  
A. N. Perezhogin ◽  
...  
Keyword(s):  
Risk Factors ◽  
Central Nervous System ◽  
Nervous System ◽  
Blood Serum ◽  
Respiratory System ◽  
Comparison Group ◽  
Fold Increase ◽  
Negative Effects ◽  
The Central Nervous System

Introduction. There is actual development of scientific and methodological support for the formation of the evidence base of the negative impact of environmental factors on public health. Material and methods. The hygienic assessment of the air quality of the territory with the placement of aluminum production and the territory without similar sources of emissions was carried out, carcinogenic and non-carcinogenic health risk was estimated, chemical-analytical and clinical-laboratory examination of 235 children was carried out to study the negative effects of the influence of the studied risk factors on critical organs and systems. Results. In the conditions of the existing quality of the atmospheric air, conditioned by the economic activity of the enterprise producing aluminum, an unacceptable risk of developing non-carcinogenic effects for the central nervous system, bone system, respiratory system, blood system, liver, kidneys (HI to 33.4) is formed. Children in the zone of exposure to risk factors have an increased (up to 4.0 times) content both of manganese, nickel, chromium in blood, and as the aluminum as fluoride ion in urine (up to 5.5 times) relative to the indices in the comparison group. Children with an elevated content of these compounds in bio medias revealed reliable deviations of laboratory parameters relative to similar parameters in children in the comparison group: a 1.2-fold increase in serum glutamic acid, a 2.2-fold increase in eosinophilia in the nasal secretion, C-terminal telopeptides, total and direct bilirubin, ACAT in blood serum by 1.2 times, β2-microglobulin in blood serum - by 1.8 times. The established negative effects in children, proven to be associated with an increased content of toxic substances in the bio medias, are confirmed by the increased detectability of functional disorders of the autonomic and central nervous system (5.5 times more often), respiratory diseases (2.9 times), musculoskeletal diseases system (in 1.3-1.5 times). Substantiated indices of negative effects must be taken into account when conducting sanitary and epidemiological examinations and developing measures for the prevention of functional diseases of the central nervous system, bone system, respiratory system, liver, kidneys in children permanently residing in a residential building in the zone of emission sources of aluminum plants.

Pulmonary Effects of Head Trauma

Neurosurgery ◽  
1981 ◽  
Vol 9 (6) ◽  
pp. 729-740 ◽  
Author(s):  
Walter Baigelman ◽  
James C. O'Brien
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Head Trauma ◽  
Head Injuries ◽  
Negative Effects ◽  
Increased Risk ◽  
The Central Nervous System ◽  
Risk Of Aspiration ◽  
The Brain ◽  
The Continuum

Abstract Knowledge of the interrelation of the central nervous system-respiratory axis is crucial to the management of patients with head injuries with or without concomitant pulmonary-thoracic problems. Damage to the central nervous system (CNS) can result in unexplained hypoxemia, noncardiac pulmonary edema, altered patterns of respiration, and an increased risk of aspiration. The damaged thorax and lung can contribute to brain ischemia and rises in intracranial pressure. The treatment of one end of the CNS-respiratory axis is not without effect on the other end of the continuum. Corticosteroids, diuretics, mannitol. iatrogenic hyperventilation, barbiturates, and vasopressors are used in the management of patients with head trauma, but may have an impact on oxygenation and ventilation. When positive end expiratory pressure is used in the management of a pulmonary process, it should be optimized and used with caution while monitoring for its effect on intrac. ial pressure. Pulmonary toilet, while remaining a necessity, must be performed in a manner so as to minimize potential negative effects on the brain. Hyperoxia and hypothermia should be avoided. Mechanical ventilation should be used as dictated by the desired PaCO2 and not as a mandatory adjunct to endotracheal intubation.

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