scholarly journals Measles immunity in different population groups

2020 ◽  
Vol 12 (1) ◽  
pp. 80-84
Author(s):  
M. A. Belopolskaya ◽  
T. D. Grigoryeva ◽  
V. Yu. Avrutin ◽  
D. V. Potanina ◽  
A. V. Dmitriev ◽  
...  

Objective: to examine the state of the immunity to measles in different age groups.Materials and methods: In 2018, 4444 people were examined at the Diagnostic Center (virological). Among them, 3783 people were examined using the passive haemagglutination test for measles (manufactured by Pasteur Research Institute of Epidemiology and Microbiology, Russia). In the remaining 661 cases, the IgG to measles were detected using the enzyme-linked immunosorbent assay (ELISA) by VektoMeaseles IgG test (manufactured by Vector-Best, Russia). The correlation between the measles IgG level (ELISA) and the age was examined in 518 patients. Results: In this study, the immunity to measles was shown to be insufficient in all groups of observed people. Even among medical staff, nearly 10% had no protective level of measles antibodies. We have shown that the correlation between the measles IgG level and the age is statistically significant, so that the number of seronegative persons in different age groups differs significantly. Conclusion: The highest ratio of seronegative individuals was found in the age group between 18 and 25 years (52,33%), which can lead to serious measles outbreaks. Hence, this study confirms a strong need for additional immunization in all groups and especially in young population.

2019 ◽  
Author(s):  
Talal El Zarif ◽  
Mohamed Faisal Kassir ◽  
Nazih Bizri ◽  
Ghida Kassir ◽  
Umayya Musharrafieh ◽  
...  

Abstract Abstract: Background: Lebanon has experienced several measles and mumps outbreaks in the past twenty years . In this article, the trend of measles outbreaks in Lebanon was studied in an attempt to outline factors contributing to the failure of elimination plans, and to provide potential solutions. The relationship between measles and mumps outbreaks in Lebanon was described and explored. Methods: A retrospective descriptive study of confirmed cases of measles and mumps in Lebanon between 2003 and 2018 collected from the Lebanese Ministry of Public Health Epidemiological Surveillance Unit public database was carried out. The information collected was graphically represented taking into consideration dates of cases, age groups affected, and vaccination status. Results: The mean number of measles cases was 150.25 cases/year in the 1-4 years age group, 87 cases/year in individuals aging between 5 and 14, and 63.68 cases/year in those > 14 years old. In the latter group, only 18.05% were unvaccinated. The mean number of mumps cases was 30.4 cases/year in the <4 year age group and 53.8 cases/year in the 10-19 years age group. During the study period, every spike in measles cases was followed by a similar spike in mumps. 9.66% of measles cases occurred in individuals who received at least 2 doses of the vaccine, 52.26% in the unvaccinated, and 38% in those whose vaccination status was undetermined. Conclusions: Measles in Lebanon is a disease of the pediatric population, but adults remain at risk. Outbreaks of mumps followed those of measles and were mainly among adolescents. Presence of a large number of Syrian refugees in the country may further complicate the situation. Vaccination activities need to be intensified. Keywords: Measles, mumps, elimination, vaccine, Lebanon.


1993 ◽  
Vol 26 (2) ◽  
pp. 77-82 ◽  
Author(s):  
Solange Artimos de Oliveira ◽  
Akira Homma ◽  
Léa Camillo-Coura ◽  
Maria Lucília P. Loureiro ◽  
Maria Teresa G. N. de Almeida

ln order to study the measles antibody behavior of three vaccination schedules, 684 children were divided into 4 Groups: Group A (341 vaccinated children under the age of one); Group B (101 children at the age of one); Group C (74 children under the age of one and one at the age of one); Group D (163 unvaccinated children with a history of measles in the past - Group control). Children of Group A presented lower rates and 25.9% of the age group under two did not show any measles antibodies. In Group B, all the children presented antibodies. In Group C onby 4.0% did not. In all age groups, the geometric mean HI antibody titers of Group A were lower than the valuesfound in the other groups. The age at vaccination was the factor of greater influence on the results of this study.


2001 ◽  
Vol 8 (1) ◽  
pp. 161-165 ◽  
Author(s):  
Mitsutaka Kuzuya ◽  
Ritsushi Fujii ◽  
Masako Hamano ◽  
Ritsuko Ohata ◽  
Hajime Ogura ◽  
...  

ABSTRACT A novel blocking enzyme-linked immunosorbent assay (BL-ELISA) was developed for detection of antibodies to human group C rotavirus (CHRV). The specificity of the BL-ELISA was confirmed by using animal sera hyperimmunized to group A and group C rotaviruses and paired sera from five patients with acute CHRV gastroenteritis. Furthermore, there was concordance between the BL-ELISA and a neutralization assay for CHRV in 226 (95%) of 238 samples. By using the BL-ELISA, we determined the seroprevalence of CHRV in 704 serum samples obtained from nine different age groups of inhabitants of Okayama Prefecture, Japan, in 1992, 1994, and 1996. As a result, 211 sera (30%) were found to be positive for CHRV antibodies. The seroprevalence gradually increased with age and reached 52.7% in the oldest individuals. A further analysis of the youngest age group suggested that CHRVs predominantly prevail in persons older than 3 years of age in Japan. When comparing the three sampling years, a larger percentage of antibody-positive sera was detected in 1994 than in either 1992 or 1996 in individuals between 6 and 15 years of age, reflecting the occurrence of a CHRV outbreak among children during the winter of 1992 to 1993 that was previously documented. These results indicate that CHRV infections may occur more frequently in spite of the relatively low detection rate of the virus.


Vaccines ◽  
2021 ◽  
Vol 9 (2) ◽  
pp. 143
Author(s):  
Florentia Kanakoudi-Tsakalidou ◽  
Evangelia Farmaki ◽  
Eleni Papadimitriou ◽  
Anna Taparkou ◽  
Eleni Agakidou ◽  
...  

Measles outbreaks have surfaced in Europe during the last decades. Infants <12 months of age were the most severely affected pediatric population. The aim of this study was to investigate the duration of maternally derived measles antibodies in infants aged 1 to 12 months in relation to maternal humoral immune status and other parameters. In a prospective, cross-sectional cohort study, 124 mother/infant pairs and 63 additional infants were recruited from October 2015 through December 2019. Infants were hospitalized in a university pediatric department of a general hospital. Demographic and epidemiological data were recorded and blood samples were collected from mothers and their infants. Commercially available enzyme-linked immunosorbent assay (ELISA) was used for measuring measles antibodies. Fifty nine percent of mothers had vaccine-induced and 15% infection-acquired measles immunity. Eighty-eight percent and 94% of infants were unprotected by 5 and 10 months of age, respectively. Maternal antibody levels and infant age were significant independent predictors of infants’ antibody levels whereas the method of maternal immunity acquisition, age, and origin [Greek/non-Greek] were not. Our findings suggest that about 90% of infants are susceptible to measles beyond the age of 4 months. To our knowledge, these are the first data from Greece reported under the current community composition and epidemiological conditions.


2020 ◽  
Vol 7 (2) ◽  
pp. 275-281
Author(s):  
Sultana Fizun Nahar ◽  
Ramesh Prasad Saha ◽  
Khan Md Ashfia ◽  
Asish Kumer Debnath ◽  
AKM Anisur Rahman ◽  
...  

Toxoplasmosis is a zoonotic protozoan parasitic disease caused by Toxoplasma gondii. The aim of the present study was to determine the prevalence of T. gondii infection in sheep, goats and cattle in Chattogram division. In his study a total of 220 sera samples from different animals were collected from different herds of Chattogram division. Among the 220 samples, 184 sera were examined for T. gondii antibody by indirect Enzyme-Linked Immunosorbent Assay (iELISA) (ID Screen® indirect ELISA kit, IDvet Laboratories, Inc., France) according to the manufacturer’s instructions. Samples with more than 50% S/P were considered as positive for T. gondii. The overall prevalence of T. gondii was 13.59%. The highest prevalence of T. gondii was found in goat 16%, sheep 13.04% and cattle 11.90%. The highest prevalence (36.36%) of T gondii infection was observed in sheep aged >5 years compared to other age groups. Similarly, the highest seroprevalence was found in >18 months old sheep (16.067% compared to <6 months group (5.88%) and pregnant (19.63%) and non-pregnant sheep (11.76%). In contrast to cattle and sheep, the seroprevalence of toxoplasmosis in goats were highest in 6 months to 18 months age group (20.83%) compared to >18 months age group (9.09%). Results indicate that T. gondii infection in food animals in Chattogram division is widespread. Further investigation on the isolation and characterization of T. gondii from the aborted fetus and its zoonotic potential on human population is imperative. The undercooked meat and raw milk of these food animals may serve as a potential source of T. gondi infection for humans. Res. Agric., Livest. Fish.7(2): 275-281,  August 2020


2020 ◽  
Author(s):  
Talal El Zarif ◽  
Mohamed Faisal Kassir ◽  
Nazih Bizri ◽  
Ghida Kassir ◽  
Umayya Musharrafieh ◽  
...  

Abstract Background: Lebanon has experienced several measles and mumps outbreaks in the past twenty years . In this article, the trend of measles outbreaks in Lebanon was studied in an attempt to outline factors contributing to the failure of elimination plans, and to provide potential solutions. The relationship between measles and mumps outbreaks in Lebanon was described and explored. Methods: A retrospective descriptive study of confirmed cases of measles and mumps in Lebanon between 2003 and 2018 collected from the Lebanese Ministry of Public Health Epidemiological Surveillance Unit public database was carried out. The information collected was graphically represented taking into consideration dates of cases, age groups affected, and vaccination status. Results: The mean number of measles cases was 150.25 cases/year in the 1-4 years age group, 87 cases/year in individuals aging between 5 and 14, and 63.68 cases/year in those > 14 years old. In the latter group, only 18.05% were unvaccinated. The mean number of mumps cases was 30.4 cases/year in the <4 year age group and 53.8 cases/year in the 10-19 years age group. During the study period, every spike in measles cases was followed by a similar spike in mumps. 9.66% of measles cases occurred in individuals who received at least 2 doses of the vaccine, 52.26% in the unvaccinated, and 38% in those whose vaccination status was undetermined. Conclusions: Measles in Lebanon is a disease of the pediatric population, but adults remain at risk. Outbreaks of mumps followed those of measles and were mainly among adolescents. Presence of a large number of Syrian refugees in the country may further complicate the situation. Vaccination activities need to be intensified. Keywords: Measles, mumps, elimination, vaccine, Lebanon.


2020 ◽  
Vol 24 (3) ◽  
Author(s):  
Noor ul Huda Maria ◽  
Asif Shabbir ◽  
Ali Hammed ◽  
Saif Salman ◽  
Qurrat Ul Ain ◽  
...  

Objective:  To evaluate the psychosocial impact of the use of digital media on young minds. Material and Methods:  A survey based cross sectional study was conducted by using questionnaires through google forms from diverse general, young population. A total number of 110 respondents from Pakistan, Jordan, and Syria, were included. Results:  18 – 35 years age group showed Depression 53.4%, Anxiety 71.8%, Lack of Interest in Daily Activities 70.5%, Decreased Decisive Ability 10.5% and Insomnia 66.3%. While, the 36 – 54 years group showed Depression 46.4%, Anxiety 56.8%, Lack of interest in Daily Activities 61.8%, Decreased Decisive Ability 8.3% and Insomnia 47.5%. It was noticeable, that the younger age group of 18 – 35 years suffered more psychological effects. Conclusion:  We concluded that while digital media is affecting all age groups, but the younger age group was affected the most.  


2021 ◽  
Vol 9 (2) ◽  
pp. 598-606
Author(s):  
Muhammad Umair Chaudhary ◽  
Abdul Ghani ◽  
Sobia Usman ◽  
Usman Farooq

Purpose of the study: The present study analyses the impact of PTV infotainment and the educative program Bazm-e-Tariq Aziz (Neelam Gher) on moulding the behaviours of youth in Pakistan. The purpose and, major focus of the study is to measure and analyses the effect of the Television program on youth education in Pakistan. Methodology: Quantitative method was used in this study. In this regard, survey was conducted from the population having diverse demographics viz: gender, age group, and education etc. Main Findings: The findings of the study depict that the PTV program Bazm-e-Tariq Aziz (Neelam Gher) has imparted knowledge, awareness, and education to the young population of Pakistan. Application of this study: The study may be applied to examine the learning behaviour of youth through infotainment programs aired on Television. Novelty / originality of this study: Electronic media plays a significant role in the dissemination of knowledge and education. Since the inception of Pakistan Television (PTV) in the country, it has been widely watched by the public of all age groups particularly the youth of the country. PTV has aired many informative and infotainment programs but the program Bazm-e-Tariq Aziz (Neelam Gher) has played a special role in educating the masses through its diverse style and programming.


2021 ◽  
Author(s):  
Jun Cai ◽  
Juan Yang ◽  
Xiaowei Deng ◽  
Cheng Peng ◽  
Xinhua Chen ◽  
...  

SARS-CoV-2 infection causes most cases of severe illness and fatality in older age groups. In China, over 85% of individuals aged ≥12 years have been vaccinated against COVID-19 (albeit with vaccines developed against historical lineages), while children aged 0-11 years are currently not eligible for vaccination (as of September 2021). The aim of this work is to assess whether the importation of Delta variant infections will shift the COVID-19 burden from adults to children. We developed an age-structured susceptible-infectious-removed model of SARS-CoV-2 transmission dynamics to simulate the epidemics triggered by the importation of Delta variant infections and project the age-specific incidence of SARS-CoV-2 infections, cases, hospitalisations, intensive care unit (ICU) admissions, and deaths. In the context of the vaccination programme targeting individuals aged ≥12 years (as of September 2021), and in the absence of non-pharmaceutical interventions, the importation of Delta variant infections could lead to widespread transmission and substantial disease burden in mainland China, even with vaccination coverage as high as 97% across the currently eligible age groups. The symptomatic SARS-CoV-2 infections and hospitalisation are projected to shift towards children and young adolescents, with 13% of symptomatic infections and 30% of hospitalisations occurring in those aged 0-11 years. Extending the vaccination roll-out to include children aged 3-11 years is estimated to dramatically decrease the burden of symptomatic infections and hospitalisations within this age group (54% and 81%, respectively), but would have a low impact on protecting infants (aged 0-2 years). Our findings highlight the need to strengthen vaccination efforts by simultaneously extending the target population and elevating vaccine effectiveness.


2008 ◽  
Vol 13 (16) ◽  
Author(s):  
A Fylaktou ◽  
K Haidopoulou ◽  
M Goutaki ◽  
E Papadimitriou ◽  
S Kalamitsiou ◽  
...  

A cross-sectional study was conducted in order to determine the prevalence of mumps and measles antibodies in a representative sample of the general population in Northern Greece between January 2004 and May 2007. Overall, 900 healthy individuals participated in the study. The great majority were found to be protected against measles. The total protection rate against mumps was significantly less (87% versus 72%, respectively; p<0.01). Compared to all other age groups, statistically significantly lower protection rates were found in children younger than 1.5 years (p<0.01). The lowest rates of all adult groups were found in the age group of 21 to 30 years (86% and 68% for measles and mumps, accordingly). In conclusion, protection rates against both measles and mumps seem to be lower than expected in certain age groups, such as infants and young adults.


Sign in / Sign up

Export Citation Format

Share Document