scholarly journals Glucose concentration monitoring using near infrared spectrum of spent dialysis fluid in hemodialysis patients

2020 ◽  
pp. 90-90
Author(s):  
Valentina Matovic ◽  
Jasna Trbojevic-Stankovic ◽  
Branislava Jeftic ◽  
Lidija Matija
Keyword(s):  
Glucose Concentration ◽  
Near Infrared ◽  
Nir Spectroscopy ◽  
Hemodialysis Patients ◽  
Maintenance Hemodialysis ◽  
Diabetic Patients ◽  
Dialysis Fluid ◽  
Major Health Problem ◽  
Hemodialysis Treatment ◽  
Spent Dialysate

Introduction/Objective. Diabetic nephropathy leading to end-stage renal disease is a major health problem worldwide. Hemodialysis treatment is associated with glycemia variations. Diabetic patients on hemodialysis might benefit from a noninvasive online glycemia monitoring system. The aim of this study was to assess the glucose concentration from the matrix of the spent dialysate fluid using Near infrared (NIR) Spectroscopy. Methods. Blood samples and spent dialysate have been collected in the 15th minute of the hemodialysis treatment from 15 patients. The spent dialysis fluid has been characterized by a NIR spectrometer in the range of 900-1300 nm. In order to apply the artificial neural network (ANN) and train it, the MATLNFTOOL program was used. The testing and training of the ANN were executed using the NIR spectrum of the spent dialysis fluid as input, and the glucose concentration as output. Results. A significant correlation in excess of 93% between the NIR spectrum of the spent dialysate and the blood glucose concentration (3-9 mmol/l) has been found. Conclusions. NIR spectroscopy is a noninvasive and reliable method of glycemia monitoring which can be used in maintenance hemodialysis patients.

scholarly journals Predicting anemia using NIR spectrum of spent dialysis fluid in hemodialysis patients

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Valentina Matović ◽  
Branislava Jeftić ◽  
Jasna Trbojević-Stanković ◽  
Lidija Matija
Keyword(s):  
Near Infrared ◽  
Binding Capacity ◽  
Nir Spectroscopy ◽  
Hemoglobin Concentration ◽  
Hemodialysis Patients ◽  
Mean Corpuscular Hemoglobin ◽  
Iron Saturation ◽  
On Line ◽  
Spent Dialysate ◽  
Iron Binding Capacity

AbstractAnemia is commonly present in hemodialysis (HD) patients and significantly affects their survival and quality of life. NIR spectroscopy and machine learning were used as a method to detect anemia in hemodialysis patients. The aim of this investigation has been to evaluate the near-infrared spectroscopy (NIRS) as a method for non-invasive on-line detection of anemia parameters from HD effluent by assessing the correlation between the spectrum of spent dialysate in the wavelength range of 700–1700 nm and the levels of hemoglobin (Hb), red blood cells (RBC), hematocrit (Hct), iron (Fe), total iron binding capacity (TIBC), ferritin (FER), mean corpuscular volume (MCV) and mean corpuscular hemoglobin concentration (MCHC) in patient blood. The obtained correlation coefficient (R) for RBC was 0.93, for Hb 0.92, for Fe 0.94, for TIBC 0.96, for FER 0.91, for Hct 0.94, for MCV 0.92, for MCHC 0.92 and for MCH 0.93. The observed high correlations between the NIR spectrum of the dialysate fluid and the levels of the studied variables support the use of NIRS as a promising method for on-line monitoring of anemia and iron saturation parameters in HD patients.

scholarly journals Designing and Implementation of Non Invasive Blood Glucose and Hemoglobin Detection using NIR

2020 ◽  
Vol 9 (11) ◽  
pp. 229-232
Keyword(s):  
Blood Sugar ◽  
Glucose Concentration ◽  
Near Infrared ◽  
Low Cost ◽  
Nir Spectroscopy ◽  
Hemoglobin Concentration ◽  
Diabetic Patients ◽  
Optical Signals ◽  
Non Invasive ◽  
Sugar Levels

our project describes the tactic of measurement of the glucose concentration and simultaneously hemoglobin within the human blood non-invasively using the painless near infrared-based optical technique. In recent practice, the concentration of glucose and hemoglobin in blood is measured using invasive techniques which generally involve pricking finger (commercial Glucometer and samples using spectroscopy). The frequent finger pricking causes damages on the skin and also increases the danger of spreading infectious diseases. So, the development of non-invasive blood sugar and hemoglobin measurement system are going to be a boon to diabetic patients. The designed system uses Near Infrared (NIR) spectroscopy to work out blood sugar levels supported transmittance spectroscopy emitting signals of 940nm wavelength. These optical signals are sent through the fingertip and reflected signals are detected by phototransistor placed beside. The glucose concentration and therefore the hemoglobin within the blood are determined by analyzing the variation within the intensity of the received signal obtained after reflection. The described system is majorly useful for diabetic patients. In our project, we used Ardunio Uno for the acquisition and processing of the signals. The developed low-cost device could avoid complicated procedures and provides continuous monitoring of glucose and hemoglobin concentration.

A Multivariate NIR Study of Skin Alterations in Diabetic Patients as Compared to Control Subjects

2000 ◽  
Vol 8 (4) ◽  
pp. 217-227 ◽  
Author(s):  
Paul Geladi ◽  
Josefina Nyström ◽  
Jan W. Eriksson ◽  
Anders Nilsson ◽  
Folke Lithner ◽  
...  
Keyword(s):  
Diabetes Complications ◽  
Near Infrared ◽  
Nir Spectroscopy ◽  
Diabetic Patients ◽  
Healthy Controls ◽  
Skin Changes ◽  
Skin Reflectance ◽  
Fibre Optic Probe ◽  
Optic Probe ◽  
Skin Conditions

A group of 15 diabetic persons with different degrees of diabetes complications, including skin changes, was studied by Fourier Transform Near Infrared (FT-NIR) spectroscopy. Skin reflectance spectra were measured with a fibre-optic probe in four locations (sites): hand, arm, leg and foot. For reference, a group of 28 healthy controls was also measured. Multivariate analysis of the NIR spectra obtained shows a high potential for classification and discrimination of the skin conditions. Valuable indications for future experiments can be observed.

scholarly journals Management of pH of dialysis fluid using Carbostar directly effects the acid-base status in maintenance hemodialysis patients

2013 ◽  
Vol 46 (7) ◽  
pp. 651-659
Author(s):  
Motoyuki Masai ◽  
Takehiko Sakai ◽  
Junji Uchino ◽  
Atsushi Ishimaru ◽  
Toru Yamamoto ◽  
...  
Keyword(s):  
Hemodialysis Patients ◽  
Maintenance Hemodialysis ◽  
Dialysis Fluid ◽  
Acid Base ◽  
Acid Base Status ◽  
Maintenance Hemodialysis Patients

scholarly journals ERECTILE DYSFUNCTION

2016 ◽  
Vol 23 (03) ◽  
pp. 268-273
Author(s):  
Ansari Muhammad Rafique ◽  
Pooran Mal ◽  
Jairamani Bhagwan Das ◽  
Shafique-Ur-Rehman Memon ◽  
Syed M Tahir ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Erectile Dysfunction ◽  
Rural Areas ◽  
Cross Sectional Study ◽  
Hemodialysis Patients ◽  
Maintenance Hemodialysis ◽  
Diabetic Patients ◽  
Cross Sectional ◽  
Male Patients

Objectives: Erectile dysfunction (ED) is a very common and distressing healthproblem in chronic maintenance hemodialysis patients. There is no such data available fromSind province of Pakistan on this issue; we want to highlight the factors and prevalence oferectile dysfunction among hemodialysis patients in this part of our country. Study Design:This hospital based observational, cross-sectional study Setting: It was conducted at 04hemodialysis centers of Hyderabad city Perod: In 2014 Methods: The Study was conductedby using International Index of Erectile Dysfunction (IIEF-5) for determination of prevalence& severity of ED among these patients. Comparative analysis for frequency of ED was alsodone between urban & rural patients. Adapted Urdu version of IIEF-5 was used for those whocannot understand English pro forma. Results: There were total 62 male patients; all of themwere on maintenance hemodialysis for more than 6 months. Their ages were between 20 to59 years with mean 36±11. In this series of patients 80% (n=50) were < 50 years of age whilethe diabetic patients were 58% (n=36). The overall prevalence of ED observed in patients was88.7% (n=55) in our study. Severe ED was seen in 30 (48.4%) patients. The prevalence &severity of ED was significantly higher in diabetes mellitus and over 50 years of age. There washigher incidence of ED 94% observed in patients who are living in rural areas as compared tourban areas patients 82%. Conclusions: It has been concluded in this study that majority ofmale hemodialysis patients were suffering from ED problem. Diabetes mellitus and & > 50 yearsof age has the highest prevalence of ED. Erectile dysfunction is very common and distressinghealth related issue among hemodialysis patients and this should be addressed with routine

scholarly journals Tinzaparin Provides Lower Lipid Profiles in Maintenance Hemodialysis Patients: A Cross-Sectional Observational Study

2014 ◽  
Vol 2014 ◽  
pp. 1-9
Author(s):  
Ming-Hsien Tsai ◽  
Yu-Wei Fang ◽  
Jyh-Gang Leu
Keyword(s):  
Multivariate Analysis ◽  
Total Cholesterol ◽  
Univariate Analysis ◽  
Serum Triglyceride ◽  
Hemodialysis Patients ◽  
Chronic Hemodialysis ◽  
Maintenance Hemodialysis ◽  
Diabetic Patients ◽  
Significant Difference ◽  
The Impact

As a low-molecular-weight heparin, tinzaparin has effectively been used as an anticoagulant during hemodialysis sessions. However, the impact of different heparin types on dyslipidemia is still controversial. In our study, 434 chronic hemodialysis patients were evaluated. The mean age was 65 ± 13. Forty-eight patients (11%) and 386 patients (89%) were in the tinzaparin and unfractionated heparin (UFH) groups, respectively. Triglyceride had significant difference between the two groups (P=0.001) but total cholesterol, HDL, or LDL did not. In the univariate analysis, the triglyceride level was significantly associated with tinzaparin use [β: −39.9, 95% confidence interval (CI): −76.7 to −3.0], and this association remained following the multivariate analysis (β: −40.8, 95% CI: −75.1 to −6.5). The difference in serum total cholesterol level between tinzaparin and UFH became significant (β: −13, 95% CI: −24.5 to −1.56) after adjustment in the multivariate analysis. Moreover, in a subgroup analysis, male diabetic patients showed lower serum triglyceride levels with the use of tinzaparin, while older, nondiabetic, male patients showed significant advantages in total cholesterol levels with the use of tinzaparin. Based on our findings, tinzaparin shows a significant association with a lower lipid profile in patients with chronic hemodialysis when compared to UFH.

Reagentless Near-Infrared Determination of Glucose in Whole Blood Using Multivariate Calibration

1992 ◽  
Vol 46 (10) ◽  
pp. 1575-1578 ◽  
Author(s):  
David M. Haaland ◽  
M. Ries Robinson ◽  
Gary W. Koepp ◽  
Edward V. Thomas ◽  
R. Philip Eaton
Keyword(s):  
Infrared Spectra ◽  
Glucose Concentration ◽  
Whole Blood ◽  
Near Infrared ◽  
Multivariate Calibration ◽  
Blood Chemistry ◽  
Standard Errors ◽  
Diabetic Patients ◽  
Blood Samples ◽  
Near Infrared Spectra

Noninvasive monitoring of glucose in diabetic patients is feasible with the use of near-infrared spectroscopic measurements. As a step toward the final goal of the development of a noninvasive monitor, the near-infrared spectra (4250 to 6600 cm−1) of glucose-doped whole blood samples were obtained along with reference glucose values. Glucose concentrations and spectra of blood samples obtained from four subjects were subjected to multivariate calibration with the use of partial least-squares (PLS) methods. The cross-validated PLS standard errors of prediction for glucose concentration based on data obtained from each individual subject's blood samples averaged 33 mg/dL over the range from 3 to 743 mg/dL. Cross-validated standard errors for glucose concentration from PLS calibrations based on data from all four subjects were 39 mg/dL. However, when PLS models based upon three subjects' data were used for prediction on the fourth, glucose prediction abilities were poor. It is suggested that blood chemistry differences were sufficiently different for the four subjects to require that a larger number of subjects be included in the calibration for adequate prediction abilities to be obtained from near-infrared spectra of blood from subjects not included in the calibration.

scholarly journals Nutritional Status of Patients on Maintenance Hemodialysis at Muhimbili National Hospital in Dar es Salaam, Tanzania: A Cross-Sectional Study

2021 ◽  
Vol 2021 ◽  
pp. 1-7
Author(s):  
Puneet Bramania ◽  
Paschal Ruggajo ◽  
Rimal Bramania ◽  
Muhiddin Mahmoud ◽  
Francis Furia
Keyword(s):  
Nutritional Status ◽  
Total Cholesterol ◽  
Hemodialysis Patients ◽  
Dar Es Salaam ◽  
Maintenance Hemodialysis ◽  
Diabetic Patients ◽  
Muhimbili National Hospital ◽  
National Hospital ◽  
Cross Sectional ◽  
Increased Risk

Background. Patients on hemodialysis therapy are at high risk of malnutrition which is attributed to multiple factors. Protein-energy malnutrition in these patients confers poor clinical outcomes. This study investigated the nutritional status of patients on maintenance hemodialysis at Muhimbili National Hospital in Dar es Salaam, Tanzania. Methods. A cross-sectional descriptive study was done among 160 adult patients on maintenance hemodialysis therapy. Data concerning patients’ personal, medical, dietary, and hemodialysis-related information were collected. Patients’ anthropometric and laboratory tests (complete blood count, albumin, total cholesterol, creatinine, and urea) were measured. The quantitative Subjective Global Assessment (SGA) dialysis malnutrition score (DMS) was used to assess their nutritional status. Data analysis was done using the SPSS software version 20. Results. Among the 160 hemodialysis patients, 49 (30.6%) were female. Patients’ mean age was 52.2 ± 13.3 years. The median duration on hemodialysis was 18 (8.25–29.75) months. Malnutrition was present in 98 (61.2%) of the patients. Severe malnutrition was found in only 3 (1.9%) patients and 16.9% were underweight. The longer duration on hemodialysis, having diabetes mellitus, and being single were associated with increased risk for malnutrition in multivariate logistic regression. Malnourished patients had significantly lower dry weight, body mass index, mid-upper arm circumference, waist circumference, albumin, total cholesterol, and creatinine levels. Conclusion. Malnutrition is very common among hemodialysis patients at Muhimbili National Hospital, especially those on longer duration of hemodialysis, and diabetic patients. We recommend that hemodialysis patients should be regularly assessed for malnutrition and appropriately treated which if left unattended heralds worse outcomes.

scholarly journals Non-invasive blood glucose measurement by near infrared spectroscopy: Machine drift, time drift and physiological effect

2010 ◽  
Vol 24 (6) ◽  
pp. 629-639 ◽  
Author(s):  
Simon C. H. Lam ◽  
Joanne W. Y. Chung ◽  
K. L. Fan ◽  
Thomas K. S. Wong
Keyword(s):  
Blood Glucose ◽  
Glucose Concentration ◽  
Near Infrared ◽  
Drift Time ◽  
Nir Spectroscopy ◽  
Physiological Effect ◽  
Blood Glucose Measurement ◽  
Partial Least Square ◽  
Glucose Measurement ◽  
Non Invasive

The aim of this paper is to evaluate development of the non-invasive blood glucose measurement of near infrared (NIR) spectroscopy. The results showed that NIR spectroscopy might obtain glucose concentration of up to 200% difference under a same environmental condition with two months apart due to time and machine drifts. These effects can restrict the development of the non-invasive blood glucose measurement. Partial least square (PLS) regression was used, which showed advantage over using simple absorbance for glucose concentration. Non-invasive blood glucose measurement of health subjects (non-diabetics) was also investigated. The results showed that R correlation coefficient of prediction (Rp) was 0.48 and root mean square of prediction (rmsep) was 1.34 mmol/l. The error was mainly due to the physiological effect of different subjects.

scholarly journals EXTENT OF HEMODIALYSIS NURSES’ PRESENCE AS PERCEIVED BY PATIENTS

2020 ◽  
Vol 6 (3) ◽  
pp. 67-72
Author(s):  
Ma. Almira Pliego Nebres ◽  
Clarence Bien Ladion Nebres ◽  
Bienvisa Ladion Nebres
Keyword(s):  
Nursing Care ◽  
Chronic Renal Disease ◽  
Hospital Setting ◽  
Hemodialysis Patients ◽  
Maintenance Hemodialysis ◽  
Spiritual Needs ◽  
Patient Relationship ◽  
Descriptive Research ◽  
Hemodialysis Treatment ◽  
Nursing Presence

Background: Nursing presence is an essential nurse caring behavior of being with the patient. This is particularly true for those with chronic renal disease and who regularly undergo maintenance hemodialysis treatment in the hospital setting. When nursing presence is perceived by patients in a nurse-patient relationship, it is more likely to result in enhanced satisfaction with the quality of nursing care. Thus, it is important for hemodialysis nurses to be aware of the relevance of nurse-patient interactions in planned care considering that these interactions are integral to the extent to which nursing presence is experienced and perceived by patients.Objective: This study aims to determine the hemodialysis nurses’ extent of nursing presence as perceived by patients undergoing hemodialysis treatment in two hospitals in Iligan City, Philippines.Methods: Utilizing the descriptive research design, the study was conducted in two hospitals in Iligan City, Philippines.  A total of 121 hemodialysis patients were purposely selected to determine their perception as to the extent of hemodialysis nurse’s nursing presence utilizing the 25-item Presence of Nursing Scale (PONS) instrument. Descriptive statistics were used for data analysis.Result: The overall rating by the hemodialysis patients in both hospitals was “always" on the hemodialysis nurses’ extent of nursing presence with an average mean score of 4.47 in all 25 items of the PONS. The highest rated item which reflects that the nurse cares for the patient as a person had an average mean score of 4.63 (always) while the lowest rated item indicating that the nurse is meeting the spiritual needs of the patient had an average mean score of 4.23 (always).Conclusion: The nurse-patient relationship is enhanced by the presence of nurses who are more responsive and interactive with the patients, resulting in patients who are more satisfied with nursing care. Thus, it is suggested that nurses in dealing with patients of varying backgrounds should consider their unique needs when giving information, explanations, health education and nursing care.

Sign in / Sign up

Export Citation Format

Share Document