scholarly journals The effect of platelet-rich fibrin (PRF) on maxillary incisor retraction rate

2020 ◽  
Author(s):  
Kuter Karakasli ◽  
Emire Aybuke Erdur
Keyword(s):  
Treatment Plan ◽  
Statistical Significance ◽  
Maxillary Incisor ◽  
Control Group ◽  
Study Group ◽  
Test Analysis ◽  
Platelet Rich Fibrin ◽  
Time Points ◽  
Significant Difference ◽  
Incisor Retraction

ABSTRACT Objective To investigate the efficiency of platelet-rich fibrin (PRF) injection on maxillary incisor retraction rate. Materials and Methods The study included 40 patients (23 women and 17 men; mean age; 20.7 ± 1.45) with Class II Division 1 malocclusion. The treatment plan for all patients was extraction of the maxillary first premolars and canine distalization, followed by retraction of the maxillary incisors. Patients were randomly divided into two groups. The study group received injectable platelet-rich fibrin (i-PRF) two times with an interval of 2 weeks; the control group did not receive i-PRF. In both groups, the measurements were bilaterally assessed as the distances between the lateral and canine teeth on the plaster models at five time points. The rate of incisor movement was evaluated by Student's t-test, analysis of variance, and Tukey honestly significant difference tests. Statistical significance was set as P < .05. Results The average movements of incisors were significantly higher in the study group than the control group at all time points (P < .05). According to the within-group comparison, none of the measurements showed any significant differences between the right and left sides in both groups at all time points (P > .05). While the movement of incisors was significantly higher in the study group in the week following the PRF injection compared to the other weeks (P < .05), there were no significant differences in the control group at all-time points (P > .05). Conclusions Applying i-PRF significantly increased the rate of maxillary incisor retraction at all time intervals. Platelet-rich fibrin injection can be an effective method for shortening treatment duration.

scholarly journals The Connection of the Level of Estradiol in Serum and Obesity with the Endometrial Bleeding in Postmenopausal Women

2019 ◽  
Vol 7 (1) ◽  
pp. 88-91 ◽  
Author(s):  
Valentina Tofiloska ◽  
Maria Krstevska ◽  
Ana Daneva-Markova ◽  
Viktorija Jovanovska
Keyword(s):  
Endometrial Cancer ◽  
Statistical Significance ◽  
Abnormal Uterine Bleeding ◽  
Control Group ◽  
Prospective Clinical Study ◽  
Study Group ◽  
Gynecology And Obstetrics ◽  
Increased Risk ◽  
Significant Difference ◽  
Post Menopausal

BACKGROUND: Postmenopausis is a period that begins one year after the last menstrual period. Abnormal uterine bleeding could be of different origins. AIM: This study aimed to determine the association of serum estrogen hormone levels and obesity with the occurrence of endometrial bleeding in post-menopausal women. MATERIAL AND METHODS: Prospective clinical study involving 120 postmenopausal patients treated at the University Clinic for Gynecology and Obstetrics-Skopje, divided into two groups: control and study. The control group consisted of 40 postmenopausal patients without endometrial bleeding, hospitalised and operated due to urogenital pathology. The study group consisted of 80 patients with endometrial bleeding who were divided into three subgroups according to the thickness of the endometrium: from 5-8 mm, 8-11 mm and above 11 mm. In all subjects, estradiol and BMI was determined. RESULTS: Estradiol levels were statistically higher in the study group compared to control while statistically significant difference among the three subgroups according to the thickness of the endometrium about the levels of estradiol in blood is not found. About BMI, the results showed that there was no statistical significance between the two examined groups. CONCLUSION: Patients with endometrial bleeding have increased levels of estradiol and are at increased risk of endometrial cancer about controls, the likelihood of endometrial cancer significantly increases by 1,108 times.

scholarly journals Tooth abnormalities in pediatric patients submitted to antineoplastic treatment for central nervous system neoplasms

2016 ◽  
Vol 19 (3) ◽  
pp. 39
Author(s):  
Ornella Florio Demasi ◽  
Marcelo Fava ◽  
Camila Merida Carrillo ◽  
Terezinha Garrett de Freitas Sampaio Amaral ◽  
Vicente Odone Filho
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Pediatric Patients ◽  
Statistical Significance ◽  
Control Group ◽  
Study Group ◽  
Central Nervous System Neoplasms ◽  
Tooth Abnormalities ◽  
Significant Difference ◽  
Nervous System Neoplasms

<strong>Objective</strong>: The aim of this study was to evaluate the frequency of tooth abnormalities in pediatric patients treated for central nervous system neoplasms. <strong>Material and methods: </strong>This cross-sectional study assessed thirty-one patients, median age 14.2 years (range 5 - 25), who were off therapy for at least one year, comparatively with a control group of thirty-one healthy patients matched for age with the study group. Tooth abnormalities were evaluated by panoramic radiographs. <strong>Results: </strong>There was no statistical significant evidence that patients of the study group (age range 5 - 25 years) have more frequency of tooth abnormalities comparatively with controls.   However, in children who were diagnosed before 5 years of age, microdontia was the most common abnormality with statistically significant difference (<em>P=</em>0.037). Root shortening grade III was observed in patients over 10 years of age at the time of radiographic examination, also with statistical significance (<em>P=</em>0.046). <strong>Conclusions: </strong>Tooth abnormalities frequency in patients treated for central nervous system neoplasms is directly related to the age of diagnosis and stage of odontogenesis. Microdontia and reduced root surface areas, the most common abnormalities observed, can lead to future oral health impairment due to malocclusion and less periodontal support. It is important to give parents and patients early orientation about maintenance of good oral hygiene and proper treatment by orthodontics or dentofacial orthopedics.

scholarly journals Oral health of prosthetic rehabilitated patients with schizophrenia

2021 ◽  
pp. 2-2
Author(s):  
Miodrag Scepanovic ◽  
Vladan Djordjevic ◽  
Ivana Stasevic-Karlicic ◽  
Ena Joksimovic ◽  
Danijela Staletovic ◽  
...  
Keyword(s):  
Oral Health ◽  
Psychiatric Patients ◽  
Statistical Significance ◽  
Control Group ◽  
Study Group ◽  
Oral Diseases ◽  
Prosthetic Rehabilitation ◽  
Significant Difference ◽  
Dmft Index ◽  
Carious Teeth

Introduction/Objective. Factors such as nature of psychiatric disorder, length of hospitalization and oral-side effects of psychotropic medications may considerably contribute to high prevalence of oral diseases among people with schizophrenia, and a consequent need for prosthetic rehabilitation. The aim of this study was to ascertain the oral health level of prosthetic rehabilitated patients with schizophrenia and to consider their needs for future improvement of prosthetic rehabilitation. Methods. The study group comprised 52 patients with schizophrenia, hospitalized at the Clinic for Mental Disorders ?Dr Laza Lazarevic? Belgrade. The control group comprised 52 patients with no psychiatric medical history, treated at the School of Dental Medicine, University in Belgrade. The oral health indices (DMFT index, CPITN and OHI-S), socio-demographic characteristics, smoking habits, oral hygiene habits and previous dental visits were registered in both groups, as well as medical characteristics of the primary disease in the study group patients. Results. Fifty percent of the study group patients had partial mobile dentures, while almost 30% had fixed dentures, in opposite to the control group patients who prevalently had fixed dentures. In both groups of patients, a statistical significance was observed between partial mobile and fixed dentures wearers, in terms of DMFT index, carious teeth, CPI modified and OHI-S. Similarly, a statistically significant difference between groups was observed concerning fixed dentures in terms of carious teeth, filled teeth, CPI modified and OHI-S. Conclusion. Multidisciplinary approach is needed for complete oral and prosthetic rehabilitation of this group of psychiatric patients.

scholarly journals Study on the correlation parameters of Class II malocclusion in child tooth dentition early stage by using 3D technique

2019 ◽  
Vol 35 (5) ◽  
Author(s):  
Peiying Xiong ◽  
Wen Sui ◽  
Wendan He ◽  
Qiaoling Lei ◽  
Wenli Gao
Keyword(s):  
3D Reconstruction ◽  
Statistical Significance ◽  
Class Ii ◽  
Control Group ◽  
Study Group ◽  
Class Ii Malocclusion ◽  
Nasolabial Angle ◽  
Significant Difference ◽  
Face Scanning ◽  
Lower Mandible

Objective: To record the dentition, jaw and facial growth and development of children with class II malocclusion at the age of 7-8 years old in the early dental transitional stage with 3D technology and to provide the study basis for the growth and development parameters of normal children and children with class II malocclusion. Methods: Twenty-four children who were suffering class-II malocclusion in the early dental transitional stage and received treatment between July 2016 and July 2017 in our hospital were selected as the study group, and 20 healthy children were selected as the control group in the same period. SIRONA CEREC dentition scanning, 3D reconstruction of the lower mandible and 3d MD face scanning were performed on the children. Relevant data were recorded and compared. Results: The dentition scanning results suggested that the study group had significantly larger anterior overbite and anterior overjet and smaller width of the upper arch than the control group; there was a significant difference between the two groups (P<0.05). The 3D reconstruction of the lower mandible suggested that the study group had smaller Go angle and SNB angle and shorter ANS-Me distance, Go-Me distance and N-Me distance compared to the control group; the differences had statistical significance (P<0.05). The face scanning results demonstrated that the nasolabial angle and facial convexity angle of the study group were significantly larger than those in the control group, and the difference was statistically significant (P<0.05). Conclusion: The dentition scanning results suggested that the study group had significantly larger anterior overbite and anterior overjet and smaller width of the upper arch than the control group; there was a significant difference between the two groups (P<0.05). The 3D reconstruction of the lower mandible suggested that the study group had smaller Go angle and SNB angle and shorter ANS-Me distance, Go-Me distance and N-Me distance compared to the control group; the differences had statistical significance (P<0.05). The face scanning results demonstrated that the nasolabial angle and facial convexity angle of the study group were significantly larger than those in the control group, and the difference was statistically significant (P<0.05). doi: https://doi.org/10.12669/pjms.35.5.592 How to cite this:Xiong P, Sui W, He W, Lei Q, Gao W. Study on the correlation parameters of Class II malocclusion in child tooth dentition early stage by using 3D technique. Pak J Med Sci. 2019;35(5):---------. doi: https://doi.org/10.12669/pjms.35.5.592 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

scholarly journals Optimal antero-posterior position of the maxillary central incisors and its relationship to the forehead in adult African American females

2018 ◽  
Vol 89 (1) ◽  
pp. 123-128 ◽  
Author(s):  
Matthew P. Gidaly ◽  
Timothy Tremont ◽  
Chee Paul Lin ◽  
Chung How Kau ◽  
Nada M. Souccar
Keyword(s):  
African American ◽  
Positive Association ◽  
Prediction Equation ◽  
Maxillary Incisor ◽  
Control Group ◽  
Study Group ◽  
Optimal Position ◽  
Significant Difference ◽  
Maxillary Incisors ◽  
The Relationship

ABSTRACT Objectives: To determine an optimal anteroposterior (AP) position of the maxillary central incisors and their relationship to the forehead in adult African American (AA) females. Materials and Methods: Smile profile photographs of 150 AA females were acquired and divided into an optimal control group (N = 48) and a study group (N = 102) based on the position of the maxillary central incisors, as judged by a panel of orthodontists and orthodontic residents. The AP position of the maxillary central incisors and the forehead inclination (FI) were measured relative to Glabella vertical (GV). A two-sample t-test was used to compare the incisor AP position and the FI between the two groups. Linear regression was used to quantify the relationship between the incisor AP position and the FI. Results: In all groups, the maxillary incisors were anterior to GV. However, a significant difference was found in the incisor AP position between the groups (8.58 ± 3.96 mm for the control group and 11.2 ± 4.48 mm for the study group; P = .001). Furthermore, the control group demonstrated a positive association between the optimal AP position of the maxillary central incisors and FI (P &lt; .0001). Conclusions: GV is a reliable landmark with which to access the AP maxillary incisor position in AA females. The optimal AP position of the maxillary central incisors is significantly associated with FI; the greater the FI, the more anterior the optimal maxillary incisor position. A prediction equation to determine the optimal position of the maxillary incisors relative to GV for AA females is proposed.

scholarly journals Effect of injectable platelet-rich fibrin (i-PRF) on the rate of tooth movement: A randomized clinical trial

2021 ◽  
Author(s):  
Emire Aybuke Erdur ◽  
Kuter Karakaslı ◽  
Elif Oncu ◽  
Bahadır Ozturk ◽  
Sema Hakkı
Keyword(s):  
Inflammatory Cytokines ◽  
Orthodontic Treatment ◽  
Tooth Movement ◽  
Gingival Crevicular Fluid ◽  
Study Group ◽  
Canine Tooth ◽  
Platelet Rich Fibrin ◽  
Time Points ◽  
Significant Difference ◽  
Crevicular Fluid

ABSTRACT Objectives To evaluate the efficiency of injectable platelet-rich fibrin (i-PRF) in accelerating canine tooth movement and to examine levels of the matrix metalloproteinase-8 (MMP-8), interleukin-1β (IL-1β), receptor activator of nuclear factor kappa-light-chain-enhancer of activated B cells ligand (RANKL), and osteoprotegerin (OPG) in the gingival crevicular fluid during orthodontic treatment. Materials and Methods Twenty patients (mean age = 21.4 ± 2.9 years) with Class II Division 1 malocclusion were included in a split-mouth study. The treatment plan for all patients was extraction of maxillary first premolars followed by canine distalization with closed-coil springs using 150 g of force on each side. The study group received i-PRF two times, with a 2-week interval, on one side of the maxilla. The contralateral side served as the control and did not receive i-PRF. Maxillary canine tooth movement was measured at five time points (T1–T5) on each side. Also, the activity of inflammatory cytokines was evaluated at three time points in the gingival crevicular fluid samples. Results There was a significant difference in canine tooth movement between the two groups (P &lt; .001). i-PRF significantly increased the rate of tooth movement, and stimulation in the levels of inflammatory cytokines supported this result (P &lt; .001). The levels of cytokines changed in both groups between T1 and T2. The IL-1β, MMP8, and RANKL values were significantly increased in the study group compared with the control group, while the OPG values were significantly decreased. Conclusions i-PRF-facilitated orthodontics is an effective and safe treatment modality to accelerate tooth movement, and this method can help shorten orthodontic treatment duration.

scholarly journals The effect of injectable platelet-rich fibrin use in the initial treatment of chronic periodontitis

2020 ◽  
Vol 148 (5-6) ◽  
pp. 280-285
Author(s):  
Mila Vuckovic ◽  
Nadja Nikolic ◽  
Jelena Milasin ◽  
Vladan Djordjevic ◽  
Iva Milinkovic ◽  
...  
Keyword(s):  
Chronic Periodontitis ◽  
Periodontal Therapy ◽  
Treatment Modalities ◽  
Control Group ◽  
Study Group ◽  
Clinical Parameters ◽  
Pocket Depth ◽  
Platelet Rich Fibrin ◽  
Number Of Patients ◽  
Significant Difference

Introduction/Objective. The objective of the study was to investigate whether there are differences in therapeutic effect between initial treatments of chronic periodontitis [scaling and root planning (SRP)] alone and SRP in conjunction with injectable platelet-rich fibrin (I-PRF) application, comparing clinical parameters after three months. Methods. Twenty-four patients with chronic periodontitis who had at least two sites with probing pocket depth (PPD) ? 5 mm on contralateral side participated in the study. Using a split-mouth design, the patients were treated with SRP + I-PRF (study group) or SRP only (control group). The clinical parameters, clinical attachment level (CAL), gingival margin level (GML), PPD, bleeding on probing, and plaque index, were recorded on both sides. Results. Compared to baseline, both treatment modalities demonstrated an improvement in investigated clinical parameters. The mean value of CAL was reduced from 1.97 ? 0.75 (0.25?3.31) to 1.07 ? 0.44 (0.12?1.78) in the study group, whereas it decreased from 1.81 ? 0.66 (0.42?2.96) to 1.48 ? 0.55 (0.22?2.30) in the control group. Similarly, the corresponding values for GML and PPD showed statistically significant difference between the groups (p = 0.040 and p = 0.006, respectively). Conclusion. Regardless the limited number of patients in the study, initial periodontal therapy in conjunction with injectable platelet-rich fibrin proved to display significant improvement in all clinical parameters compared to initial periodontal therapy alone.

scholarly journals Evaluation of complete blood count parameters in the first trimester: an early indicator of miscarriage?

2021 ◽  
Vol 6 (1) ◽  
pp. 48-52
Author(s):  
İbrahim Kale ◽  
Çağlar Helvacıoğlu ◽  
Tuğba Erel Muğurtay
Keyword(s):  
Blood Count ◽  
Complete Blood Count ◽  
Statistical Significance ◽  
First Trimester ◽  
Control Group ◽  
Study Group ◽  
Significant Difference ◽  
The Relationship ◽  
Objective Investigation

Objective. Investigation of the relationship between the first trimester complete blood count parameters and miscarriage. Materials and Methods. The study group consisted of 39 patients who admitted to the hospital with the diagnosis of abortus imminens between January 2016 and December 2019, and whose pregnancy ended as miscarriage before the 20th week. The control group consisted of 200 randomly selected healthy pregnant women, with follow-up and delivery in our hospital. Patient information was obtained retrospectively from the hospital records. Results. Age and BMI of both groups were similar. There was no significant difference between the two groups in terms of basophil, neutrophil, eosinophil, lymphocyte, monocyte, platelets, RBC, hemoglobin, hematocrit, MCV, MCH, MCHC, RDW, MPV, Pct and PDW, while leukocyte and neutrophil counts was statistically significantly higher in the miscarriage group (p=0,002, p=0,001, respectively). NLR was statistically higher in the miscarriage group (p=0,005), PLR was also higher in the miscarriage group, but this did not reach statistical significance (p=0,056). Both groups were similar in terms of MLR. Conclusions. High NLR levels obtained from the hemogram results in the first trimester seems to be associated with miscarriage. NLR can be an easy, cheap and useful tool for predicting pregnancy prognosis in patients with abortus imminens.

scholarly journals The impact of Ki-67 index, squamous differentiation and several clinicopathologic parameters on the recurrence of low and intermediate-risk endometrial cancer

2021 ◽  
Author(s):  
Birol Ocak ◽  
Fatma Öz Atalay ◽  
Ahmet Bilgehan Sahin ◽  
Mine Ozsen ◽  
Bahar Dakiki ◽  
...  
Keyword(s):  
Multivariate Analysis ◽  
Histopathological Examination ◽  
Medical Center ◽  
Statistical Significance ◽  
Control Group ◽  
Study Group ◽  
Intermediate Risk ◽  
Ki 67 ◽  
Significant Difference ◽  
The Impact

Endometrial endometrioid carcinoma (EEC) represents approximately 75–80% of endometrial carcinoma cases. Three hundred thirty-six patients with EEC followed-up in the authors’ medical center between and 2010–2018 were included in our study. Two hundred seventy-two low- and intermediate- EEC patients were identified using the European Society for Medical Oncology criteria and confirmed by histopathological examination. Recurrence was reported in 17 of these patients. The study group consisted of patients with relapse. A control group of 51 patients was formed at a ratio of 3:1 according to age, stage, and grade, similar to that in the study group. Of the 17 patients with recurrent disease, 13 patients (76.5%) were stage 1A, and 4 patients (23.5%) were stage 1B. No significant difference was found in age, stage, and grade between the case and control groups (p>0.05). Body mass index, parity, tumor size, lower uterine segment involvement, SqD, and Ki-67 index with p<0.25 in the univariate logistic regression analysis were included in the multivariate analysis. Ki-67 was statistically significant in multivariate analysis (p=0.018); however, there was no statistical significance in SqD and other parameters. Our data suggest that the Ki-67 index rather than SqD needs to be assessed for recurrence in patients with low- and intermediate-risk EEC.

Comparative study of Clinical Characteristics in Patients with Mild and Severe Reflux Esophagitis

2020 ◽  
Vol 66 (1) ◽  
pp. 19-22
Author(s):  
Melania Macarie ◽  
Simona Maria Bataga ◽  
Monica Pantea ◽  
Razvan Opaschi ◽  
Simona Mocan ◽  
...  
Keyword(s):  
Risk Factors ◽  
Sex Ratio ◽  
Hiatal Hernia ◽  
Statistical Significance ◽  
Erosive Esophagitis ◽  
Male Gender ◽  
Consecutive Series ◽  
Study Group ◽  
Entire Study ◽  
Significant Difference

AbstractObjective: This study aims to determine the correlation between risk factors and erosive esophagitis development.Methods: We conducted a retrospective observational study on a consecutive series of 19.672 patients who underwent upper gastrointestinal endoscopy between 01.01.2011-31.12.2017. A total of 3005 patients, diagnosed with erosive esophagitis, were included in the present study and stratified according to Los Angeles classification.Results: During the studied period we found 3005 patients with erosive esophagitis, sex ratio male to female was 1.3/1, the most common forms of esophagitis being grade A and B: 74.54% patients with esophagitis grade A, 14.80% patients with grade B; 5.29% patients were with grade C and 5.35% patients with esophagitis grade D. In severe esophagitis the male predominance was more prevalent (249 males, 71 female), with a sex ratio 3.50/1. The correlation of male gender with severe esophagitis was highly statistically significant (p < 0.0001, OR 2.97; 95% CI 2.25-3.91). Hiatal hernia was diagnosed in 1171 patients, the presence of large hiatal hernias, being an important predictor, with statistical significance (p < 0.0001, OR 3.41; 95% CI 2.22-5.21), for severe esophagitis development. Incidence of Helicobacter pylori infection was 11.51%, in the entire study group, with no statistical significant difference between patients with mild or severe esophagitis (12.02% vs 7.18%).Conclusion: Erosive esophagitis is a frequent disease, the most common forms being grade A and B. Male gender and the presence of hiatal hernia are the most important risk factors for erosive esophagitis development, in our study group.

Sign in / Sign up

Export Citation Format

Share Document