scholarly journals ANTI-PROLAKTIN SEBAGAI PENGHAMBAT PROSES MOULTING

2005 ◽  
Vol 11 (1) ◽  
pp. 25-29
Author(s):  
Husni Anwar ◽  
Erma Safitri

A experimental study had been done using anti-prolactin as moulting process inhibitor and toknow the affect of anti-prolactin on the time of egg laying recovery of laying bird. The objective of this study was to prove that, moulting phase can be stopped with pasif imunisation antiprolactin intra muscular. The stages of this study as follow: used anti-prolactin from the third stage of study with the dose of 50 mg/ml (P1), 100 mg/ml (P2), and 200 mg/ml (P3) and 0.5 ml PBS (as control). In this stage, moulting was ceased respectively in day 4.8 1.033 (P1); 4.6 0.843 (P2); 4.68 0.516 (P3) and 61.9 2.079 (control). Statistical test using one way Anova revealed significant difference (p < 0.01) between control and treatment groups, and BNT 5 percent test showed that the fastest moulting inhibition was found in P3 group (200 mg/ml), which was not significantly different (p less than 0.05) with P1 (50 mg/ml) and P2 (100 mg/ml). The time of egg laying recovery was respectively at 9.3 0.675 (PI); 7.4 0.843 (P2); 3.3 0.823 (P3) and 18.4 1.174 (control). Statistical test using one way Anova test showed significant difference (p less than 0.01) between control and treatment groups, and BNT 5 percent test indicated that the shortest time of egg laying recovery was at group P3 (200 mg/ml), which was significantly different (p less than 0.05) from Pl (50 mg/ml); P2 (100 mg/ml); and control (PBS 0.5 ml). Conclusively, anti prolactin (50 mg/ml, 100 mg/ml and 200 mg/ml) to inhibit moulting process and to affect the time of egg laying recovery.

2017 ◽  
Vol 2 (4) ◽  
pp. 77-80
Author(s):  
Yusef Dostar ◽  
Alireza Gorjani ◽  
Mehrdad Hashemi ◽  
Rambod Rezapour Shahir

Background and objective: To study the time-dependent effects of ischemia – reperfusion on myocardium cells. Methodology: Male SD rats (270-330gr) were randomly grouped in four groups of 10 in an experimental study. After anesthesia using pentobarbital sodium (50-60 IP-kg/mg) the rats’ hearts in the treatment groups were isolated immediately and connected to langendorff apparatus with krebs solution at 37ºC and a fixed pressure. During stabilization, 30m ischemia and 60, 90, and 120min reperfusion was carried out on the hearts. Hearts of the control group remained intact. Immunhistochemistry of apoptotic cells was performed using TUNEL POD Kit and positive TUNEL myocardium cells of each group, in five microscopic view fields, was counted. The results were represented as mean ± SD. Findings: Apoptotic cell counts in control group was 1±0.4, and this figure in the treatment groups T/60min, T/90min, and T/120min was 2.0±0.5, 3.0±0.3, and 6.0±0.3 respectively. Comparison between the treatment groups and control group was carried out using one-way ANOVA and the results showed no significant difference between the groups T/90min and T/120min and the groups T/60 and control (p>0.05). However, the differences between the groups T/120min and T/60min (p<0.001) and groups T/120min and T/90min (p<0.01) was significant. Conclusion: The study showed that ischemia-reperfusion time can be effective on apoptotic changes of myocardium cells of heart.


Parasitology ◽  
1941 ◽  
Vol 33 (1) ◽  
pp. 40-46 ◽  
Author(s):  
A. J. Haddow

1. Isolated unmated female body-lice were worn in pillboxes between the skin and the clothes. They were kept constantly on the body but, by a simple device, groups of ten were permitted feeding periods of different length. These groups were fed for 4, 8, 12, 16, 20 and 24 hr. per day respectively. Another group of ten were never allowed to feed after the last moult.2. Some of the figures for egg yield were high. Lice in the 24 hr. group were able to maintain a rate of ten eggs per day for 4−5 days at a time.3. No significant difference in longevity or rate of egg-laying was found to exist between the 12, 16, 20 and 24 hr. groups nor between the 4 and 8 hr. groups but a pronounced and significant difference exists between the 8 and 12 hr. groups. Below 12 hr. there is a sharp fall in longevity and rate of egg production. The unfed group all died, without laying, on the third day.4. The rate of laying as shown by the mode increases progressively with increase in time allowed daily for feeding.5. With regard to the mean eggs per louse the position is less clear. It is felt that the 24 hr. group may differ significantly from the 12, 16 and 20 hr. groups but this is uncertain.


2019 ◽  
Vol 5 (10) ◽  
pp. 835
Author(s):  
Adyagunita Karini ◽  
Dian Filianti

Comparing the financial performance of banks with other countries would show if the different standards and regulations affect their performance. This research aims to know if there is a significant difference in financial performance of sharia banks between Indonesia, Malaysia, Brunei and Thailand during 2011-2016. The samples used in this research consist of one sharia bank from each country: Bank Syariah Mandiri, Maybank Islamic Berhad, Bank Islam Brunei Darussalam and Islamic Bank of Thailand. This research uses a comparative quantitativeapproach using Non Performing Financing (NPF), Financing to Deposit Ratio (FDR), Return on Asset (ROA), and Capital Adequacy Ratio (CAR) as variables to indicate financial performance. One-Way ANOVA is used as the analysis technique. Results of the ANOVA test show there is a significant difference in NPF, FDR, ROA and CAR between sharia banks in Indonesia, Malaysia, Brunei and Thaiand as indicated by a significance value of 0,000 and 0,002.


1975 ◽  
Vol 15 (72) ◽  
pp. 25 ◽  
Author(s):  
DA Little

Pregnant multiparous Brahman cross cows grazing native pasture at Samford in south-east Queensland were allotted to three treatment groups in late winter; one group received a daily supplement of 180 g crude protein (as peanut meal) plus 10 g phosphorus (P), the second group 10 g P and the third (control) group neither protein nor P. The P and control groups received approximately 320 g DOM per day, mainly composed of sugar and grain, to balance the DOM provided to the protein + P group as peanut meal. Supplementation continued for a period approximately spanning the third to eighth months of gestation. The protein plus phosphorus supplement significantly reduced the interval from calving to first postpartum oestrus by 46 per cent; all animals in this group had exhibited oestrus within two months of calving. By three months after calving, only 50 per cent of controls and 70 per cent of those given phosphorus had exhibited oestrus. Calf growth was unaffected by the supplements. Samples of grazed pasture were collected using non-pregnant cows with oesophageal fistulae. The provision of P or P plus protein tended to render the animals less selective in their grazing. The evidence suggested that the higher feed requirements of the pregnant cows removed any possible effect of the supplements on their selectivity. Native pasture provided a slightly sub maintenance ration during the period of supplementation, and a major limiting nutrient appeared to be protein.


1986 ◽  
Vol 14 (4) ◽  
pp. 390-399 ◽  
Author(s):  
D. V. Tuxen ◽  
J. F. Cade

The possible beneficial effect of aprotinin, a broad protease inhibitor, on the incidence and outcome of ARDS was examined in two complementary studies. In the first study, the effect of aprotinin was assessed in 147 patients admitted with multiple trauma or shock. In the 57 patients who developed ARDS, mortality was significantly less in those who had previously received aprotinin (8/20, 40%) than in those who had not (26/37, 70%). Although both treatment groups were well matched, this was a retrospective study and a second prospective, randomised, controlled study was therefore carried out. In 78 patients at risk of ARDS, there was no significant difference between treated and control patients in the incidence, duration or severity of ARDS, or in mortality or other major complications. It is concluded that aprotinin is not effective in improving any aspect of ARDS or its outcome in seriously ill patients.


2019 ◽  
Vol 7 (1) ◽  
pp. 826-835
Author(s):  
Yosi Julianti ◽  
Untung Sudharmono

Critical Hepatitisis is the inflammation of the liver that is caused by viruses, alchol and drugs which are characterized by the increasing values of SGOT SGPT. The purpose of this study is to determine the effectiveness of fig leaves (Ficuss carica L) steeping water towards the decrease of SGOT SGPT serum on male wistar rats in critical hepatitis model. The object of this study is 30 male wistar rats with the age of 2-3 months and weight 180-200 grams and randomly divide into 3 groups, which are the negative group that is only by giving an usual food and drink, the positive group and the treatment groups are given paracetamol 120mg/ oral for 7 days. The treatment group is given 0.65 gram/ day of fig leaves steeping water for 7 days. One way ANOVA of SPSS version 24 is used to analyze this research. The result of the study shows that there is a significant difference in SGOT serum level between the treatment group, positive group and negative group (p<0,05). And there is a significant difference  in SGPT level between the treatment group and the positive group (p<0,05). The conclusion of this study is tin leaves (Ficus carica L) steeping water has an effect towards the decrease of SGOT SGPT in male Wistar rats in critical hepatitis model.


2017 ◽  
Vol 5 (1) ◽  
pp. 23-33
Author(s):  
Mega Mirawati Mirawati ◽  
Estu Lestari Lestari

Tuberculosis is an infectious disease caused by Mycobacterium tuberculosis. This disease is a health problem in the community. Minimal checks that need to be done to confirm pulmonary tuberculosis diagnostics are smear examinations. ZiehlNelseen method is an inspection method recommended by WHO. Sputum used to make preparations is a mucopurulent sputum. This can lead to infected laboratory workers if inhaled droplets containing Mycobacterium tuberculosis. This study aims to determine the effect of fuchsin carbolic acid and sputum heating before the preparation of the smear result. Temperature used 60oC, 70oC, 80oC and 90oC and control is sputum staining with Ziehl Neelsen method. The samples used positive smear sputum. The experimental research design and data were analyzed with Kruskal Wallistest. The research was conducted at the Bacteriology Laboratory of Medical Laboratory Technology Poltekkes Kemenkes Jakarta III in February to October 2016. The result of statistical test showed p> 0,301 which means there was no significant difference between the dyeing result by using sputum which has been given carbolic fuchsin and heating before the preparation with the result staining method ZiehlNeelsen. The conclusion of this method can coloring Mycobacterium tuberculosis bacteria.


DENTA ◽  
2019 ◽  
Vol 11 (2) ◽  
pp. 29
Author(s):  
Kristin Gaby Rosari ◽  
Noengki Prameswari ◽  
Lisdiana Mardanus

<p><strong><em>Background:</em></strong><em>Maxillary expansion uses mechanical forces to open the maxillary suture which causes inflammation and bone remodeling around the area. Stichopus hermanni is known to contain flavonoid, chondroitin sulfate, and saponin which is used to inhibit inflammatory process, increase bone metabolism and mineralization, and wound healing. <strong>Purpose:</strong> The aim of this experiment is to know the effect of Stichopus hermanni to bigonial width on maxillary suture remodeling expansion using cephalometric analysis. </em><strong><em>Materials and </em></strong><strong><em>Methods: </em></strong><em>Experimental units used were 24 male Cavia cobaya divided into 4 groups (n=6). Group K(-) is negative control. Helical spring was applied  and activated in the other 3 groups for 10 days. Group K(+) was given 2% NaCMC gel, both group P1 and P2 was given 3% Stichopus hermanni gel. Group P2 were also given retention period for 10 days after activation period. Cavia cobaya were then decapitated and observed for the bigonial width changes. The data was analyzed with One Way ANOVA test continued with LSD test. <strong>Result</strong></em><strong><em>s</em></strong><strong><em>:</em></strong><em> The result of ANOVA test showed siginficant differences among the treatment groups p=0,000 (p&lt;0,05). LSD test showed  significant differences between group K(-) and K(+) (Sig. 0,005), K(-) and P1 (Sig. 0,001), and group K(-) and P2 (Sig. 0,000). <strong>Conclusion: </strong>3% Stichopus hermanni gel increases bigonial width but not significant in remodeling process on maxillary suture expansion.</em></p><p><em> </em></p><p><strong><em>Keywords:  </em></strong><em>Stichopus hermanni, bone remodeling, maxillary suture expansion, bigonial width, cephalometric analysis</em></p><p><strong><em> </em></strong></p><p><strong><em>Correspondence: </em></strong><em>Noengki Prameswari, Department of Orthodontics, Faculty of Dentistry, Hang Tuah University, Arif Rahman Hakim 150, Surabaya, Phone 031-5945864, 5912191, Email: </em><a href="mailto:[email protected]"><em>[email protected]</em></a><em></em></p>


2020 ◽  
Author(s):  
Jérémy Campillo ◽  
Cédric B. CHESNAIS ◽  
Sébastien D. Pion ◽  
Jacques Gardon ◽  
Joseph Kamgno ◽  
...  

Abstract Background Little information is available on the effect of ivermectin on the third and fourth stage larvae of Onchocerca volvulus . To assess a possible prophylactic effect of ivermectin on this parasite, we compared the effects of different ivermectin regimens on the acquisition of onchocercal nodules. Methods We analyzed data from a controlled randomized clinical trial of ivermectin conducted in the Mbam valley (Cameroon) between 1994 and 1998 in a cohort of onchocerciasis infected individuals. The number of nodules that appeared between the start and the end of the clinical trial was analyzed, using ANOVA and multivariable Poisson regressions, between four treatment arms: 150 µg/kg annually, 800 µg/kg annually, 150 µg/kg 3-monthly, and 800 µg/kg annually. Results The mean number of nodules that appeared during the trial was reduced by 17.7% in subjects treated 3-monthly compared to those treated annually (regardless of the dose). Poisson regression model, adjusting on subject’s age and weight, initial number of nodules and intensity of O. volvulus infection in his village of residence, confirmed that the incidence of new nodules was reduced in 3-monthly treatment arms compared to annually treatment arms, and that the dosage of ivermectin does not seem to influence this effect. Besides, the number of newly acquired nodules was positively associated with the initial number of nodules. Analysis of disappearance of nodules did not show any significant difference between the treatment groups. Conclusions Our result suggest, for the first time in humans, that ivermectin has a prophylactic effect on O. volvulus . Three-monthly treatment seems more effective than annual treatment to prevent the appearance of nodules.


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