scholarly journals Clinical appearance of oral lesions in bronchial asthma patients using inhalation drug

2020 ◽  
Vol 32 (3) ◽  
pp. 207
Author(s):  
Audrey Amber Vieri ◽  
Rosiliwati Wihardja ◽  
Tenny Setiani Dewi
Keyword(s):  
Bronchial Asthma ◽  
Oral Lesion ◽  
Inhalation Therapy ◽  
Orthodontic Appliances ◽  
Oral Lesions ◽  
Inhaled Drugs ◽  
Clinical Appearance ◽  
Saliva Secretion ◽  
Asthma Patients ◽  
One Year

Introduction: Inhalation therapy has become the first-line treatment for bronchial asthma patients. Studies have proved that not all of the inhaled drugs reach the target organ, but mostly are deposited in the mouth and cause local immunosuppressant and decrease saliva secretion. These conditions are closely linked to some adverse effects in the mouth. The purpose of this study was to describe the clinical appearance of oral lesion in bronchial asthma patients using inhalation drugs. Methods: This study was descriptive and conducted on 30 bronchial asthma patients that have been using inhalation drug for at least one year, free of other systemic diseases, not using denture and orthodontic appliances. Oral mucosa was examined, and any oral lesion was recorded. Results: The most number of oral lesions found in patients through clinical examinations were plaque (73.3%), followed by a fissure (36.7%), atrophy (30%), and the least oral lesions found were pigmentation (3.3%), bullae (3.3%), and petechiae (3.3%). The lesions found in patients using inhalation drugs in a range of up to 10 years were found more varyingly. Conclusion: Plaque, fissure, atrophy, pigmentation, bullae, and petechiae are oral lesions that are clinically found in bronchial asthma patients using inhalation drugs.

scholarly journals Periodontal clinical features of bronchial asthma patient using inhalation drugs

2021 ◽  
Vol 33 (3) ◽  
pp. 217
Author(s):  
Maria Efrinta Ginting ◽  
Rosiliwati Wihardja ◽  
Dyah Nindita Carolina
Keyword(s):  
Periodontal Disease ◽  
Clinical Features ◽  
Bronchial Asthma ◽  
Periodontal Pocket ◽  
Periodontal Status ◽  
Asthmatic Patients ◽  
Gingival Bleeding ◽  
Periodontal Index ◽  
Asthma Patients ◽  
One Year

Introduction: Bronchial asthma patients use inhalation drugs as therapy to achieve a controlled asthma state. Inhaled corticosteroids and β2 agonists are the medication that is being used in this case. Prolonged use of inhalation drugs will affect the health of periodontal tissue. The effect of these drugs can reduce the periodontal defense mechanism and increase the risk of periodontal disease. This study aims to determine the periodontal clinical features of bronchial asthma patients using inhalation drugs. Method: This research was a descriptive study. The sample of the study were 22 females and 8 males bronchial asthma patients at the Community Lung Health Center of Bandung (Balai Besar Kesehatan Paru Masyarakat Bandung/BBKPM Bandung) who had been using inhalation drugs for at least one year. The periodontal clinical feature was assessed by employing a Community Periodontal Index (CPI) modified with probing the gingival sulcus to assess the presence of gingival bleeding, periodontal pocket, and loss of clinical attachment where then a periodontal status was obtained. The periodontal status data were then processed using the periodontitis case definitions from the Centers for Disease Control and Prevention/American Academy of Periodontology (CDC/AAP) to determine periodontal disease in asthmatics patients. Results: Clinical features of gingival bleeding were found in 26 asthmatic patients (86.7%), periodontal pockets in 18 asthmatic patients (60%), and loss of clinical attachment in 27 asthmatic patients (90%). Based on the CDC/AAP case definition, 23 asthmatic patients (76.7%) had periodontitis. Bronchial asthma patients who used inhalation drugs had a risk of periodontitis.Conclusion: Bronchial asthma patients who used inhalation drugs for at least one year had gingival bleeding and loss of clinical attachment and periodontal pocket.

scholarly journals Pigmented Oral Lesions: A Multicenter Study

2021 ◽  
Author(s):  
Kittipong Dhanuthai ◽  
Natchaya Theungtin ◽  
Natnicha Theungtin ◽  
Pantira Thep-akrapong ◽  
Sompid Kintarak ◽  
...  
Keyword(s):  
Buccal Mucosa ◽  
Demographic Data ◽  
Oral Pathology ◽  
Oral Lesion ◽  
Oral Lesions ◽  
Clinical Appearance ◽  
Pigmented Lesions ◽  
Prince Of Songkla University ◽  
The Mean ◽  
University Department

Abstract Objectives The aim of this study was to determine the prevalence and clinical features of pigmented oral lesions from Thailand. Materials and Methods Biopsy records of the Department of Oral Pathology, Chulalongkorn University, Department of Oral Diagnosis, KhonKaen University, Department of Oral Biology and Oral Diagnostic Sciences, Chiangmai University, Department of Stomatology, Prince of Songkla University, and Rangsit University were reviewed for oral pigmented lesions diagnosed during 1999 to 2019. Demographic data were culled from the biopsy records. Ages of the patients were subdivided into 10-year intervals. Locations of the lesions were classified as gingiva, labial/buccal mucosa, palate, floor of the mouth, tongue, as well as the combination of sites. Data were analyzed by descriptive statistics using SPSS version 20.0. Results Of the 47,175 accessioned cases, 241 cases (0.51%) were diagnosed in the category of pigmented oral lesions. The age of the patients ranged from 1 month to 88 years with the mean ± standard deviation = 38.74 ± 20.96 years. Regarding gender, 172 patients (71.37%) with pigmented lesions were females, while 69 patients (28.63%) were males. The female-to-male ratio was 2.49:1. The majority of the pigmented lesions were encountered at the gingiva (29.88%) followed by labial/buccal mucosa (26.97%), palate (14.94%), lip (10.79%), alveolar mucosa (9.54%), and others (7.88%), respectively. The three most common pigmented oral lesions in the present study were nevus (39.83%), followed by melanotic macule (28.63%) and amalgam tattoo (17.43%), respectively. Conclusions The most common pigmented oral lesion in the present study is nevus. Demographic data of the patients in the present study are in accordance with previous studies with minor differences. Even though pigmented lesions of the oral cavity constitute a small portion of the oral pathology biopsies, accurate diagnosis is important since there is an overlap in clinical appearance of benign pigmented lesions and melanoma.

MYCOPLASMA AND CHLAMYDIA AS ETHIOLOGICAL FACTORS OF BRONCHIAL ASTHMA IN TERMS OF ETHNOGENESIS

2013 ◽  
Vol 68 (7) ◽  
pp. 57-60
Author(s):  
O. A. Sharavii ◽  
S. V. Smirnova
Keyword(s):  
Immune Response ◽  
Chlamydia Trachomatis ◽  
Blood Serum ◽  
Bronchial Asthma ◽  
Mycoplasma Hominis ◽  
Acute Stage ◽  
Control Group ◽  
Clinical Markers ◽  
Chlamydophila Psittaci ◽  
Asthma Patients

 Aim. The study of the prevalence and clinical peculiarities of Mycoplasmosis and Chlamydiosis in patients with different pathogenic forms of bronchial asthma (BA) taking into account ethnicity of a patient. Subjects and Methods. The research covered 239 subjects – both the Europeoids and the Mongoloids in the city of Krasnoyarsk and the town of Kyzyl, all of them being BA patients of different stages, including acute stage and practically healthy. We had determined antigens Mycoplasma pneumoniae, Mycoplasma hominis, Chlamydophila pneumoniae, Chlamydophila psittaci and Chlamydia trachomatis in smears of mucosa of pharynx and antibodies to these antigens in peripheral blood serum. Results.  We found high frequency of Mycoplasmosis and Chlamydiosis in the inhabitants of Eastern Siberia, BA patients with different pathogenic forms as compared to control group. We had determined ethnic peculiarities of specific immune response: IgM to М. pneumoniae was revealed in the Europoids more frequently than in the Mongoloids, but IgM to С. pneumoniae and to C. trachomatis, C. trachomatis antigens had been revealed more often in the Mongoloids than in the Europoids. We accepted as clinical equivalents of Mycoplasmosis and Chlamydiosis diagnostics the following signs: temperature around 37C (subfebrile temperature), non-intensive but stable coughing with scanty mucous and muco-purulent sputum, dyspnea of mixed character. Conclusions. Mycoplasma and Chlamydia are meaningful etiologic factors of bronchial asthma. We have found the peculiarities of immune response depending on ethnicity of a patient (ethnic belonging). Clinical markers of Mycoplasmosis and Chlamydiosis should be taken into account in bronchial asthma in order to provide diagnostics timely as well as eradication of infection agents. Because of insufficient knowledge of problem of bronchial asthma related to contamination with Мycoplasma and Chlamydia we put the goal to study the frequency of Mycoplasmosis and Chlamydiosis occurrence in bronchial asthma patients and determine the characteristics clinical course of diseases. We defined antigens Мycoplasma pneumoniae, Мycoplasma hominis, Chlamydophila pneumoniaе, Chlamydophila psittaci, Chlamydia trachomatis in smears of oropharynx mucosa and antibodies to them in blood serum. 

Comparison between Compliance of Fluticasone Propionate Diskhaler and of Fluticasone Propionate Diskus in Adult Bronchial Asthma Patients

Respiration ◽  
2006 ◽  
Vol 73 (5) ◽  
pp. 680-684 ◽  
Author(s):  
Takashi Hasegawa ◽  
Eiichi Suzuki ◽  
Katsuya Fujimori ◽  
Takuro Sakagami ◽  
Shinichi Toyabe ◽  
...  
Keyword(s):  
Fluticasone Propionate ◽  
Bronchial Asthma ◽  
Asthma Patients

scholarly journals Prevalence and Predictors of Metabolic Syndrome among Patients with Bronchial Asthma: A Cross Sectional Study

2021 ◽  
Vol 15 (1) ◽  
pp. 14-18
Author(s):  
Abdellah H.K. Ali
Keyword(s):  
Metabolic Syndrome ◽  
Blood Sugar ◽  
Bronchial Asthma ◽  
Density Lipoprotein ◽  
Patient Characteristics ◽  
Cross Sectional Study ◽  
Metabolic Abnormality ◽  
Fasting Blood Sugar ◽  
Cross Sectional ◽  
Asthma Patients

Background: Recent studies have reported the epidemiological link between Metabolic Syndrome (MS) and asthma, but it has rarely been studied in Egypt. The study aimed to investigate the prevalence of MS and its predictors among asthma patients in Egypt. Methods: In total, 320 patients with bronchial asthma were included. The following were assessed: spirometric evaluation, anthropometric indices, blood pressure, fasting blood sugar and serum lipid profile. We analyzed the correlation between metabolic scores and patient characteristics. Predictors of MS were identified using logistic regression analysis. Results: The prevalence of MS was 57.5% in asthma patients. For asthma patients, low High-Density Lipoprotein (HDL) and abdominal obesity were the commonest metabolic abnormality. Waist circumference, Fasting Blood Sugar (FBS) and triglyceride correlated significantly with asthma (P ‹ 0.05). FBS and DBP were the best predictors of MS. Conclusion: MS is frequent in asthma patients in Egypt. Obesity and lipid abnormalities were the commonest metabolic abnormality. Screening of these patients for components of metabolic syndrome should be a part of routine workup.

scholarly journals Inhaled medication for asthma management: evaluation of how asthma patients, medical students, and doctors use the different devices

2003 ◽  
Vol 29 (2) ◽  
pp. 75-81 ◽  
Author(s):  
Janaína Barbosa Muniz ◽  
Carlos Roberto Padovani ◽  
Irma Godoy
Keyword(s):  
Health Care ◽  
Medical Students ◽  
Health Care Professionals ◽  
Airflow Obstruction ◽  
Asthma Management ◽  
Outpatient Service ◽  
Inhalation Therapy ◽  
Metered Dose ◽  
Asthma Patients ◽  
Inhaled Medication

Asthma results from a combination of three essential features: airflow obstruction, hyperresponsiveness of airways to endogenous or exogenous stimuli and inflammation. Inadequacy of the techniques to use different inhalation devices is one of the causes of therapeutic failure. The main purpose of this study was to evaluate how 20 medical students, 36 resident physicians of Internal Medicine/Pediatrics, and 40 asthma patients used three devices for inhalation therapy containing placebo. All patients were followed at the Pulmonary Outpatient Service of Botucatu Medical School and had been using inhaled medication for at least six months. The following devices were evaluated: metered dose inhalers (MDI), dry powder inhalers (DPI), and MDI attached to a spacer device. A single observer applied a protocol containing the main steps necessary to obtain a good inhaler technique to follow and grade the use of different devices. Health care professionals tested all three devices and patients tested only the device being used on their management. MDI was the device best known by doctors and patients. MDI use was associated with errors related to the coordination between inspiration and device activation. Failure to exhale completely before inhalation of the powder was the most frequent error observed with DPI use. In summary, patients did not receive precise instruction on how to use inhaled medication and health care professionals were not well prepared to adequately teach their patients.

scholarly journals Opistorchis felineus invasion influence on immunity in bronchial asthma

2010 ◽  
Vol 9 (3) ◽  
pp. 85-90
Author(s):  
L. M. Ogorodova ◽  
M. B. Freidin ◽  
A. E. Sazonov ◽  
O. S. Fyodorova ◽  
I. A. Deyev ◽  
...  
Keyword(s):  
Experimental Study ◽  
Immune Response ◽  
Bronchial Asthma ◽  
Cell Cultures ◽  
Molecular Mechanisms ◽  
Opisthorchis Felineus ◽  
Genes Expression ◽  
Asthma Patients ◽  
Human Immune Response ◽  
Human Immune

To investigate the molecular mechanisms of human immune response modification by Opisthorchis felineus antigens in bronchial asthma. The experimental study was performed with cell cultures from patients with bronchial asthma, patients with opisthorchiasis, and patients with BA and opisthorchiasis co-occurred. A proposed down-regulation of immune response by higher level of IL10 and TGFB genes expression in patients with opisthorchiasis was revealed.

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