scholarly journals PEMERIKSAAN PROTHROMBIN TIME DAN ACTIVATED PARTIAL THROMBOPLASTIN TIME DENGAN HUMACLOT VA SERTA SYSMEX CA 500

Author(s):  
Misnah Misnah ◽  
Agus Alim Abdullah ◽  
Mansyur Arif ◽  
Burhanuddin Bahar

Prothrombin Time (PT) and an activated Partial Thromboplastin Time (aPTT) are routine coagulation tests used for pre-operative screening. The analytical step as one of the laboratory test’s stage that plays the role in the determination of the test is influenced by several factors, one of them is choosing its proper devices. The aim of this study was to know the correlation of the PT and aPTT test’s result using Humaclot VA and Sysmex CA 500 devices. A cross sectional study has been done at the Clinical Pathology Laboratory of Wahidin Sudirohusodo Hospital Makassar started from May 2009 until June 2009. The data were analyzed with T and Pearson’s Correlation test. From the 50 samples were obtained the percentage of the corresponding frequency of the PT results between Humaclot VA and Sysmex CA 500 about 84%, whereas the frequency of the corresponding results aPPT between Humaclot VA and Sysmex CA 500 is 76%, the Pearson correlation test for PT=0.58, and aPTT=0.38. There were found the suitability of PT, aPTT of Humaclot VA with CA 500 and both tools have a positive correlation.

2014 ◽  
Vol 2014 ◽  
pp. 1-7 ◽  
Author(s):  
Nnamani Nnenna Adaeze ◽  
Anthony Uchenna Emeribe ◽  
Idris Abdullahi Nasiru ◽  
Adamu Babayo ◽  
Emmanuel K. Uko

Introduction. Several biomedical findings have established the effects of hypertension on haemostasis and roles of blood coagulation products in the clinical course of hypertension.Methods. This cross-sectional study aimed at determining effects of hypertension on prothrombin time (PT) and activated partial thromboplastin time (APTT) in hypertensive patients in comparison with normotensive subjects attending a tertiary hospital in Calabar. Forty-two (42) hypertensive patients and thirty-nine (39) normotensive control subjects were investigated for PT and APTT using Quick one-stage methods.Results. Systolic blood pressure (SBP) and diastolic blood pressure (DBP) correlated positively with APTT (r=0.3072,r=0.4988;P<0.05) in hypertensive patients. DBP, SBP, PT, and APTT were significantly higher in hypertensive patients when compared to normotensive subjects (P<0.05). DBP correlated negatively with duration of illness (r=-0.3097;P<0.05) in hypertensive patients and positively with age of normotensive subjects (r=0.3523;P<0.05).Conclusion. The results obtained indicated that measurements of PT and APTT may serve as indices for evaluating hemostatic abnormalities in hypertensive patients and guide for antihypertensive therapy. However, to have better understanding of hemostatic activities in hypertension, it is recommended to conduct D-dimer, platelet factors, and protein assays.


2021 ◽  
Vol 9 (4) ◽  
pp. 3907-3912
Author(s):  
Subha Pragathi Kanniappan ◽  
◽  
Vishnu Vardhan G.D ◽  

Background: Osteoarthritis (OA) is one of the commonest forms of joint disease, and the knee is one of the most commonly affected joints. OA is clinically associated with pain, joint stiffness, joint deformity and swelling. Kinesiophobia is a condition in which a patient has an excessive, irritational, and debilitating fear of physical movement and activity resulting from a feeling of vulnerability to painful injury or reinjury. This study addresses the influence of biological (eg: X-ray changes) as well as severity of pain, kinesiophobia in individual physical functioning. The purpose of the study aims to know the prevalence of kinesiophobia in patients with OA knee. Methodology: A simple random sampling of 30 patients with diagnosed OA knee who visited Pravara Rural hospital (Loni) was included. The patients included were between the age group of 40 - 80 years and were screened according to inclusion and exclusion criteria. The data collection includes the application of scales (Tampa scale of Kinesiophobia-11) which includes 11 items, WOMAC (3 components), VAS to all the 30 subjects and was taken by the principal investigator. The total scores of each scale were analyzed mean and standard deviation were taken. Pearson correlation test was performed to know the correlation between each component. Result: Pearson correlation test was performed which showed a positive correlation between all the four variables i.e. stage of OA, VAS, TSK 11, WOMAC with r= 0.0312. Conclusion: The present study concluded that as there is progression in level or stage of OA there is increase in severity of pain which leads to further increase in level of kinesiophobia in individuals with OA of knee. This all components furthers leads to decrease in physical functioning in individuals with OA knee. KEY WORDS: Osteoarthritis, knee, Kinesiophobia, TSK11, WOMAC, VAS.


2015 ◽  
Vol 10 (1) ◽  
pp. 26-29 ◽  
Author(s):  
Fayeza Karim ◽  
Qazi Shamima Akter ◽  
Shamima Jahan ◽  
Afruza Khanom ◽  
Samira Haque ◽  
...  

Background: Complication of diabetes mellitus (DM) includes coagulation impairment. Hypercoagulable state in patient with DM may accelerate thromboembolic risk for cardiovascular disease (CVD).Objective: To assess Prothrombin Time and Activated Partial Thromboplastin Time in type 2 diabetes mellitus for observing their coagubility status.Methods: This cross sectional study was conducted in the Department of Physiology, Dhaka Medical College, Dhaka from July 2013 to June 2014. One hundred male patients with type 2 diabetes mellitus aged 40-60 years and one hundred age, BMI matched healthy subjects were included as control in this study. Patients were selected from BIRDEM, Dhaka. Prothrombin Time (PT), Activated Partial Thromboplastin Time (APTT) were estimated by auto analyzer. For statistical analysis unpaired student’t test was used.Results: In this study PT and APTT were significantly (P<0.001) lower in diabetes mellitus than those of control group.Conclusion: From this study, it may be concluded that diabetic patients are prone to develop coagulation impairment.Bangladesh Soc Physiol. 2015, June; 10(1): 26-29


Author(s):  
Faris Lazwar Irkhami

ABSTRACTStress can be perceived as a response to threats situations (either physical or psychological) caused by individual inability  to overcome existing threats within his/her environment. Job stress is the result of interaction between an individual (i.e. a worker) and his/her occupation. The objective of this study to identify the factor affecting tojob stress by the divers at PT. X. This study applied cross-sectional design conducted by observing the divers at PT. X. The population of this study was all divers working at PT. X. Data was analyzed by Spearman Correlation Test, Pearson Correlation Test, and Chi-square Test. The results of this study is strong correlation between personality type and job stress (as indicated by correlation coefficient 0.645). The divers’ age (correlation coefficient -0.283), educational level (correlation coefficient -0.220), years of service/experience (correlation coefficient -0.158), length of diving session (correlation coefficient 0.083), and threats of marine animal attack (correlation coefficient 0.156) had lower correlation with job stress. While the divers residence might also affect their job stress (as indicated by correlation coefficient 0.539).Keywords: job stress, diver


Author(s):  
Sri Ramulu Kadiyala ◽  
Karthik Rao ◽  
Nr Rao ◽  
Ram Bhat ◽  
Jayaprakash Rao ◽  
...  

Objective: The aim of this study was to find the association of postprandial blood glucose with hypercoagulability in comparison to fasting blood sugars(FBS) in diabetic and healthy patients.Methods: The present study involved a total of 156 patients, of which 78 were taken as cases (diabetics) and other 78 as controls (non-diabetics). Laboratory analysis included prothrombin time (PT), activated partial thromboplastin time (APTT), fibrinogen assay done along with fasting, and postprandial sugars.Results: Platelets in diabetics and healthy controls were in normal range. Decrease in PT and partial thromboplastin time was noted in diabetics compared to non-diabetic controls. Fibrinogen levels were increased in cases compared to controls. Changes in PT values were more significant with postprandial blood sugar (PPBS) levels when compared to FBS levels, and APTT follows the same pattern with more in PPBS levels and FBS levels in diabetics. PPBS showed elevated fibrinogen when compared to FBS in diabetics as well as non-diabetics.Conclusion: Type 2 diabetes mellitus is a hypercoagulable state as proven by the following results of our study.


2019 ◽  
Vol 13 (1) ◽  
pp. 41
Author(s):  
Susanti Tria Jaya ◽  
Johanes C Mose ◽  
Farid Husin ◽  
Jusuf S Effendi ◽  
Deny K Sunjaya

Rujukan pelayanan kesehatan merupakan salah satu upaya untuk penanganan kasus emergensi yang mengatur pelimpahan tugas dan tanggung jawab pelayanan kesehatan secara timbal balik, baik vertikal maupun horizontal. Memperkuat sistem rujukan merupakan salah satu cara dalam mempercepat penurunan angka kematian ibu. Upaya tersebut tidak terlepas dari penanganan kasus emergensi di fasilitas pelayanan kesehatan melalui peningkatan PONED di puskesmas dan PONEK di rumah sakit. Untuk mendukung pelayanan PONED dan PONEK dibutuhkan pembentukan sistem rujukan yang sesuai standar. Pelaksanaan Rujukan yang terorganisir harus dilakukan dengan syarat dan persiapan yang tepat untuk merujuk kasus kegawatdaruratan ibu dan bayi secara tepat dan cepat.  Tujuan penelitian ini adalah menganalisis hubungan sumberdaya manusia, sarana prasarana, komunikasi PONED – PONEK, dan standar operasional prosedur dengan syarat dan persiapan rujukan puskesmas PONED.Desain penelitian observasional analitik kuantitatif dengan metode survei, pendekatan waktu cross sectional. Pengukuran data menggunakan pemodelan Rasch dengan mengubah data ordinal menjadi data interval dalam bentuk logit. Populasi dalam penelitian ini adalah Tim inti PONEDdari 18 Puskesmas PONED di  Wilayah Bagian Utara Provinsi Aceh. Sampel berjumlah 72 orang diambil secara total sampling. Variabel diukur menggunakan kuesioner. Analisis bivariabel menggunakan Pearson Correlation Test sedangkan untuk multivariabel menggunakan Multiple Linear Regression.Hasil penelitian menunjukkan bahwa syarat dan persiapan rujukan belum sesuai standar, umpan balik dari RS PONEK ke Puskesmas PONED sangat susah dilaksanakan, sumberdaya manusia tidak memenuhi kualifikasi standar minimal Puskesmas PONED dan belum terlatih, sarana prasarana rujukan yang tersedia untuk di ambulan belum cukup, komunikasi PONED–PONEK masih satu arah dan standar operasional prosedur belum lengkap, dan tidak diletakkan di tempat yang mudah dilihat petugas. Hasil analisis Multiple Linear Regression menunjukkan bahwa variabel yang paling dominan berhubungan dengan syarat dan persiapan rujukan adalah standar operasional prosedur (p<0,001). Simpulan dalam penelitian ini adalah pelaksanaan rujukan puskesmas PONED yang sesuai standar masih belum tercapai, belum semua sumberdaya manusia yang tersedia memenuhi kualifikasi Puskesmas PONED. Diharapkan dukungan dinas kesehatan akan berpengaruh pada kesiapan rujukan Puskesmas PONED yang berkualitas.


2021 ◽  
Vol 5 (1) ◽  
pp. 13
Author(s):  
Ichda Nabiela Amiria Asykarie ◽  
Lusi Epsilawati ◽  
Ria Noerianingsih Firman ◽  
Farina Pramanik

Objectives: The aim of this research is to know about the correlation between calcium levels and mandibular height and length in elderly patients from panoramic radiographs. Materials and Methods: This study was a cross-sectional observational study, using 15 panoramic radiographs of patients aged 60-80 years, where each subject is taken calcium levels. Radiographs were analyzed to measure the length of the mandibular body and the height of the mandibular ramus. ImageJ software is used as a measuring tool, and the results are then correlated with the Pearson correlation test analysis. Results: This study obtained the average result for mandibular length was ± 10 cm and for mandibular height was ± 7 cm, while the calcium value showed an average value of ± 8.7-10 mg/dl. Pearson correlation test showed no significant relationship between mandibular length and height and calcium levels in the elderly. Conclusion: The conclusion drawn was that there is no significant relationship between mandibular height and length on calcium levels in the elderly as assessed by panoramic radiographs.


2020 ◽  
Vol 9 (1) ◽  
pp. 140-146
Author(s):  
Zakaria Sendy Wardana ◽  
Gadis Meinar Sari ◽  
Damayanti Tinduh

This study used a cross sectional study method using 39 obese women aged 19-22 years old, Body Mass Index (BMI) 25-35 kg / m2 and Percentage Body Fat (PBF) above 30%, normal blood pressure, heart rate normal rest and normal Hemoglobin (Hb). IGF-1 levels were measured using the Enzym Link Immunosorbent Assay (ELISA) method, while the FBG measurements used ACCU-CHEK® Performance. Data analysis techniques used the Pearson Correlation test with the Statistical Package for Social Science (SPSS). The results obtained an average level of IGF-1 (11,530 ± 4,397) ng / mL and an average FBG (90,153 ± 6,659) mg / dL       (r = 0.379) and (p = 0.017). Based on the results of the study, it’s concluded that there is a positive correlation of IGF-1 levels with FBG in obese women. Further research is needed to explain the physiological mechanism of the relation between IGF-1 and FBG in more detail


2019 ◽  
Vol 8 (1) ◽  
pp. 22
Author(s):  
Ratnadewi Ratnadewi

Zinc deficiency is public health problem. Almost two million people in developing country suffered zinc deficiency. Zinc deficiency in Indonesia, 25% in breastfeeding mothers and 17% in babies. The purpose of this study was to determine the correlation of zinc level in breastmilk with 4-6 months old baby weight and length in Padang City West Sumatera. This study was done in working area of Lubuk Buaya, Padang Pasir, and Nanggalo Public Health Center. This study was done from January 2016 until January 2017. The design of this study was cross sectional, number of sample were 108 people. Samples were selected by simple random sampling. Zinc level in breastmilk was checked by AAS (Atomic Absorption Spectrophotometer). Data were analyzed by using univariate and bivariate with pearson correlation test. The correlation test, correlation was positive and patterned between log zinc level in breastmilk with 4-6 months old baby weight (r=0,272), while the length (r=0,216), correlation was positive and weak with p value <0,05. That there were significant correlation between log zinc level in breastmilk and 4-6 months old baby weight and length.


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