Geophysical Variables and Behavior: XVII. Mental Retardation and Seasonality of Birth: A Racial Analysis

1984 ◽  
Vol 54 (3) ◽  
pp. 915-920
Author(s):  
Bernard J. Gallagher ◽  
Brian J. Jones ◽  
Joseph A. McFalls

The records of 1174 mentally retarded people were analyzed with regard to patterns of seasonality of birth. A population model was derived from birth records of the general population born during the same time period as the mentally retarded people. Log-linear analyses uncovered no significant differences between the seasons of birth for the mentally retarded and those in the general population. There were also no significant relationships when the data were analyzed by race and sex. Given the sample size and the sophistication of the analytic model, these results have important implications for an unresolved literature.

2020 ◽  
pp. 135245852091049 ◽  
Author(s):  
Kelsi A Smith ◽  
Sarah Burkill ◽  
Ayako Hiyoshi ◽  
Tomas Olsson ◽  
Shahram Bahmanyar ◽  
...  

Background: People with multiple sclerosis (pwMS) have increased comorbid disease (CMD) risk. Most previous studies have not considered overall CMD burden. Objective: To describe lifetime CMD burden among pwMS. Methods: PwMS identified using Swedish registers between 1968 and 2012 ( n = 25,476) were matched by sex, age, and county of residence with general-population comparators ( n = 251,170). Prevalence, prevalence ratios (PRs), survival functions, and hazard ratios by MS status, age, and time period compared seven CMD: autoimmune, cardiovascular, depression, diabetes, respiratory, renal, and seizures. Results: The magnitude of the PRs for each CMD and age group decreased across time, with higher PRs in earlier time periods. Before 1990, younger age groups had higher PRs, and after 1990, older age groups had higher PRs. Male pwMS had higher burden compared with females. Overall, renal, respiratory, and seizures had the highest PRs. Before 2001, 50% of pwMS received a first/additional CMD diagnosis 20 years prior to people without MS, which reduced to 4 years after 2001. PwMS had four times higher rates of first/additional diagnoses in earlier time periods, which reduced to less than two times higher in recent time periods compared to people without MS. Conclusion: Swedish pwMS have increased CMD burden compared with the general population, but this has reduced over time.


1990 ◽  
Vol 156 (4) ◽  
pp. 525-530 ◽  
Author(s):  
Olav M. Linaker

The frequency of psychotropic and anticonvulsant drug use in 168 institutionalised mentally retarded adults was studied. Use of neuroleptics and anticonvulsants was more frequent and use of hypnotics and antidepressants less frequent than in the general population. Neuroleptics were given to 49% of the population. Clients with no psychiatric diagnosis consumed less neuroleptics than those with such a diagnosis, and there was a non-significant trend for those with a more serious diagnosis (e.g. schizophrenia) to take a higher dosage. The degree of disruptive behaviour and the availability of a physician were related to dosage of neuroleptics. The various psychiatric diagnoses given could explain only a small proportion of the variance in dosage.


1969 ◽  
Vol 35 (8) ◽  
pp. 609-616 ◽  
Author(s):  
Jerome D. Schein ◽  
John A. Salvia

Recent studies of mentally retarded children have found substantially higher rates of color blindness than are usually reported for the general population. In 2 of these studies, sex differences in color blindness, invariably found in intellectually normal children, do not appear. Reanalysis of data from one of the studies of retarded children suggests the possibility that the high rates arise from the difficulty in comprehending the test and following the directions rather than from faulty color vision. However, even if the number of color blind retarded children is actually lower than these studies show, the need for research on this topic seems apparent. Using color dependent instructional materials with color blind, mentally retarded children may be detrimental.


2020 ◽  
Vol 9 (1) ◽  
pp. 15
Author(s):  
Ahsan Samad ◽  
Erdiansyah Erdiansyah ◽  
Rina Wulandari

The purpose of this study is to identify and describe the impact and behavior of the community on post-disaster economic conditions in the city of Palu and to know the local government's public policies in handling these cases. Using qualitative methods with a case study approach, literature study, and secondary data processing from various social elements. In addition, data collection was carried out by interviewing informants who felt the direct impact of the earthquake, tsunami and liquefaction in Palu, Sigi and Donggala. The results showed that the post-disaster impact felt by the people of Palu City was generally in the "severe" classification. The socio-economic conditions of the people of Palu include several aspects, ranging from the geographical conditions that are in disaster-prone zones, to the extremely poor health conditions after the disaster. The conclusion of this research shows that the escalation of natural disasters in the city of Palu is considered quite large because it consists of three types of disasters, namely the Earthquake, Tsunami and Liquifation in the same time period. Palu City is the capital of the Province as well as the economic and administrative center of Central Sulawesi Province. Damage to warehousing infrastructure coupled with massive looting from unscrupulous people in logistics supply warehouses resulted in goods that were supposed to be distributed both to the city and the district finally unable to be implemented.Tujuan penelitian ini yaitu mengidentifikasi dan mendeskripsikan evaluasi dampak dan perilaku masyarakat terhadap kondisi perekonomian pasca bencana di kota Palu dan mengetahui kebijakan publik pemerintah setempat dalam menangani kasus tersebut. Menggunakan metode kualitatif dengan pendekatan  studi kasus, studi literature, dan pengolahan data sekunder dari berbagai elemen sosial. Selain itu pengambilan data dilakukan dengan cara wawacara kepada narasumber yang merasakan dampak langsung dari bencana gempa,tsunami dan likuifaksi di Palu,Sigi dan Donggala. Hasil penelitian memperlihatkan bahwa dampak pasca bencana yang dirasakan oleh masyarakat Kota Palu secara umum berada pada klasifikasi “berat”. Kondisi sosial ekonomi masyarakat kota Palu meliputi beberapa aspek, mulai dari kondisi geografis yang berada pada zona rawan bencana, kondisi kesehatan sangat memprihatinkan pasca bencana. Kesimpulan penelitain ini menujukkan bahwa eskalasi bencana alam kota Palu dinilai cukup besar karena terdiri dari tiga macam bencana yaitu Gempa Bumi, Tsunami dan Liquifasi dalam kurun waktu sama. Kota Palu merupakan ibukota Provinsi sekaligus sebagai pusat ekonomi dan pemerintahan Provinsi Sulawesi Tengah. Rusaknya infrakstruktur pergudangan ditambah dengan adanya penjarahan yang massiv dari oknum masyarakat pada gudang-gudang suplai logistik mengakibatkan barang yang semestinya didistribusikan baik ke kota ataupun ke kabupaten akhirnya tidak dapat dilaksanakan.


Author(s):  
Franklin Sargunaraj ◽  
Justin R. St. Juliana ◽  
Cynthia J. Downs ◽  
Irina S. Khokhlova ◽  
Lee Koren ◽  
...  

Abstract Glucocorticoid hormone levels vary within a forager based upon environmental stressors such as illumination and riskier habitats, and a forager’s response to environmental variables depends upon its glucocorticoid levels. Here, we report on a laboratory experiment in which we manipulated cortisol in Allenbyi’s gerbils (Gerbillus andersoni allenbyi) to test the relationship between cortisol and behavior. We then quantified the resulting blood cortisol levels and feeding behavior in gerbils. Thirty gerbils were injected with 21-day slow-release cortisol pellets drawn from 5 different dosages. We quantified the physiological response to pellet implantation in gerbils by measuring cortisol level in blood serum using ELISA (Enzyme Linked Immunosorbent Assay). We fed gerbils daily by mixing millet seeds into the sand inside rodent cages and measured the remaining seeds the following day to quantify feeding efforts. Some evidence supports that subcutaneous supplementation of glucocorticoids (GCs) in the gerbils led to higher blood serum levels. Cortisol levels varied according to time period of measurement. Gerbils that received lower dosages consumed most of the food presented to them when compared to those receiving the highest doses. In this manner, we delineate a pattern on cortisol hormone level variation over time following dosing and consequences in feeding behavior.


2019 ◽  
Vol 207 (5) ◽  
pp. 320-325 ◽  
Author(s):  
John Briere ◽  
Omin Kwon ◽  
Randye J. Semple ◽  
Natacha Godbout

1978 ◽  
Vol 133 (4) ◽  
pp. 358-360 ◽  
Author(s):  
Carol Buck ◽  
Helen Simpson

SummaryThe season of birth distribution of 1,039 sibs of Canadian schizophrenic patients was compared with that of births in the Canadian general population over the same time period. The excess of winter births observed among the schizophrenics was not found among their sibs.


2016 ◽  
Vol 31 (20) ◽  
pp. 3413-3442 ◽  
Author(s):  
Ton Mooij

Gender and sexual orientation are expressed in heterosexual, lesbian (L), gay (G), bisexual (B), transgender (T), or queer (Q) interests and behavior. Compared with heterosexual persons, LGBTQ persons seem to experience more antisocial behavior, including negative discrimination and violence. To assess differences in LGBTQ-related discrimination in schools, the question for this research is “Do the degrees of violence experienced and feeling unsafe of LGBTQ students and staff in a school differ from those of non-LGBTQ students and staff in the same school?” Secondary analysis was carried out on data from a Dutch national digital monitor survey on safety in secondary schools. In 2006, 2008, and 2010, participation amounted to 570 schools, 18,300 teaching and support staff, and 216,000 students. Four indicators were constructed at the school level: two Mokken Scale means assessing severity of violence experienced and two Alpha Scale means assessing feeling unsafe. Analysis of mean differences showed that LGB students experienced more violence and felt less safe than non-LGB students; LGB staff felt less safe in school than non-LGB staff. When LGB students experienced more violence at school than non-LGB students, LGB students also felt less safe than non-LGB students for all 3 years. No such relationships existed for LGB staff, or between LGB staff and LGB students. No significant relationships were found between the four LGB school indicators and contextual school variables. The outcomes and uniqueness of the study are discussed. Recommendations are made to improve assessment and promote prosocial behavior of students and staff in schools.


Blood ◽  
2005 ◽  
Vol 106 (11) ◽  
pp. 2259-2259
Author(s):  
Michael Dickson ◽  
Samir H. Mody ◽  
Brahim Bookhart ◽  
Marya Zilberberg

Abstract Background: Recent guidelines from the Infectious Diseases Society of America (IDSA) for the management of Chronic Kidney Disease (CKD) in HIV+ patients highlight that up to 30% of HIV+ patients have abnormal kidney function. These guidelines also discuss the effects of CKD on HIV disease progression and the need to diagnose and manage CKD in patients with HIV. While the presence of CKD is associated with an increased rate of anemia in the general population, the prevalence of anemia among HIV patients with CKD is less well known. This is of particular importance as anemia is known to occur in at least 20% of HIV patients overall. The current analysis was undertaken to determine the distribution of kidney function levels among HIV patients and to stratify anemia risk based on these levels. Methods: In a retrospective cross-sectional analysis of data collected between 1996 and 2004 from an integrated, commercial database of claims and laboratory values, subjects with HIV infection designated by ICD-9 code were identified. Subjects were included if they were at least 17.5 years old and had at least 1 value during this time period for plasma creatinine (PCr), serum urea nitrogen (SUN), albumin (Alb) and hemoglobin (Hb). If a subject had multiple lab values recorded, only the most recent lab value was utilized for the analysis. Subjects with any diagnosis or procedure code pertaining to dialysis were excluded. Kidney function was assessed by glomerular filtration rate (GFR) and calculated using the modification of diet in renal disease (MDRD) method as follows: GFR= 170 x [PCr]−0.999 x [Age] −0.176 x [SUN] −0.170 x [Alb]+0.318 x [0.762 if female] x [1.18 if black]. Since race was not reported in the database, this parameter was not included in the calculation. Anemia was defined as Hb <13 g/dL for men; <12 g/dL for women. Results: Of the 2,032 subjects identified with HIV, 840 (41%) met the inclusion criteria. The mean age of these subjects was 43.7±12.6 years; 72% were male; mean Hb was 14.3±1.6 g/dL. Mean GFR was 91.1±21.1 mL/min/1.73m3. See Table 1 for the incidence of anemia associated with increasing severity of CKD. Conclusions: Overall prevalence of GFR <90 mL/min/1.73m3 among HIV patients was 48.5%. This is similar to the 43.5% demonstrated in a recent analysis of HIV patients,1 and higher than the 35.9% seen in the general population.2 It may, however, be an overestimate of the actual prevalence of CKD, since race was not analyzed. In addition, patients with GFRs ≥ 60 mL/min/1.73m3 require data on proteinuria to diagnose CKD. As is the case in the general population, anemia increases in prevalence with severity of CKD. Anemia in either CKD or HIV patients is associated with increased morbidity and mortality3,4; therefore, a prompt diagnosis of anemia is warranted, as it may impact clinical treatments and outcomes in this population. Table 1: Incidence of anemia associated with worsening GFR GFR (mL/min/1.73m3)* N (%) Anemia N (% total) *lower values mean worsening kidney function. ≥ 90 433 (51.5) 52 (12) 60–89 359 (42.7) 32 (9) 30–59 44 (5.3) 11 (25) 15–29 4 (0.5) 3 (75) <15 0 0


2017 ◽  
Vol 44 (3) ◽  
pp. 314-318 ◽  
Author(s):  
Emma E. van Daalen ◽  
Chinar Rahmattulla ◽  
Ron Wolterbeek ◽  
Jan A. Bruijn ◽  
Ingeborg M. Bajema

Objective.Previous studies have reported an increased malignancy risk preceding antineutrophil cytoplasmic antibody–associated vasculitis (AAV), suggesting common pathogenic pathways in these 2 entities. However, the study results were conflicting and often limited to patients with granulomatosis with polyangiitis (GPA). Here, we study the malignancy risk prior to AAV diagnosis [either GPA or microscopic polyangiitis (MPA)] to elaborate on the putative association between malignancy and AAV.Methods.A total of 203 patients were selected for the current study. Malignancies prior to AAV diagnosis were identified using a nationwide pathology database, and their occurrence was verified by reviewing the medical files of 145 patients (71.4%). The malignancy incidence was compared to the general population by calculation of standardized incidence ratios (SIR), matching for sex, age, and time period. SIR were calculated for 2 intervals: < 2 years and ≥ 2 years prior to AAV diagnosis. Separate analyses were performed for GPA and MPA.Results.The overall risk for malignancy prior to AAV diagnosis was similar to that of the general population (SIR 0.96, 95% CI 0.55–1.57), as was true when risks were analyzed by malignancy type, including skin, bladder, kidney, lung, stomach, rectum, and uterus (SIR ranged from 1.64 to 4.14). We found no significant difference in malignancy risk between patients with GPA and MPA.Conclusion.Our findings do not support the hypothesis that preceding malignancies and AAV have a causal relationship or shared pathogenic pathways.


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