scholarly journals Interrelationships among selected essential elements in medicinal plant raw materials and their water-extractable forms

2013 ◽  
Vol 59 (2) ◽  
pp. 46-58
Author(s):  
Paweł Konieczyński ◽  
Marek Wesołowski
Keyword(s):  
Medicinal Plant ◽  
Raw Materials ◽  
Principal Component ◽  
Essential Elements ◽  
Water Soluble ◽  
Plant Materials ◽  
Plant Raw Materials ◽  
Plant Parts ◽  
Plant Samples ◽  
Water Extractable

Summary In the study, the relationships were investigated among N, P, Fe, Zn, Mn and Cu, in medicinal plant raw materials (herbal bags) and their water-soluble chemical forms in infuses. 42 independent samples of plant materials were chosen, represented by different morphological plant parts as herbs, leaves, flowers and fruits. The elements were determined by UV/Vis spectrometry (non-metals), and FAAS (metallic elements) after previous mineralization of plant samples (total concentrations), and directly in herbal teas (water-extractable forms). Most frequently the correlations between non-metals and Zn and Mn occurred, both between their total contents the water-extractable forms. Statistically significant correlations were also found in pairs: Zn-Mn, Fe-Zn, Mn-Fe, and Cu-Zn. Application of multivariate analysis revealed that cluster analysis grouped the studied samples into clusters with similar levels of the analyzed elements, and principal component analysis allowed the identification of water-extractable Zn, P-PO4 and water-extractable Cu as the most crucial factors determining the differentiation of the studied plant samples.

scholarly journals Members of the family Lamiaceae Lindl. as sources of medicinal plant raw materials to obtain neurotropic drugs

2020 ◽  
Vol 8 (1) ◽  
pp. 4-28
Author(s):  
Е. V. Zvezdina ◽  
J. V. Dayronas ◽  
I. I. Bochkareva ◽  
I. N. Zilfikarov ◽  
E. Yu. Babaeva ◽  
...  
Keyword(s):  
Medicinal Plant ◽  
Scientific Literature ◽  
Raw Materials ◽  
Neurotropic Activity ◽  
Biologically Active ◽  
Plant Materials ◽  
Plant Raw Materials ◽  
Pharmaceutical Substances ◽  
The Family ◽  
Active Substances

The aim of this work is to review and analyze the data published in the modern scientific literature obtained in pharmacological, pharmacognostic and pharmacotechnological studies of various types of raw materials obtained from members of the family Lamiaceae L., which were sources of biologically active substances, pharmaceutical substances, total extracts and the drugs – with a neurotropic activity.Materials and methods. For the review, we used the information of scientific literature from open and accessible sources of the last twenty years, located in the scientific and technical libraries of institutions, as well as in electronic databases: Elibrary, PubMed, Scopus, Cyberleninka, GoogleAcademy, J-Stage. The search inquiries were: the species of the family Lamiaceae (Russian and Latin), the samples of medicinal plant materials based on them as well as the names of the drugs and biologically active substances obtained from these raw materials.Results. When working with the sources of scientific information, the main attention was paid to pharmacologic tests performed during the studies on laboratory animals and proving the presence of neurotropic activity in the studied objects – essential oils and extracts from plant raw materials: aqueous, aqueous alcoholic, and methanol ones. It has been established that the potential of the therapeutic and preventive application of pharmaceutical substances and drugs based on the medicinal plant materials obtained from 30 genera members of the Lamiaceae family, remains unrealized despite the close attention of various researchers.Conclusion. This review comprised 71 species from 30 genera. Despite the significant level of the previous study presented in the analysis of this publication, an enormous potential of this family’s species remains unexplored. In the future, they can be of both – pharmacognostic and practical interest, in particular, in creation of new medicinal preparations of the neurotropic action based on them.

scholarly journals OBTAINING PLANT MATERIALS SIBERIAN IRIS (IRIS SIBIRICA L.) BY METHODS OF BIOTECHNOLOGY

2018 ◽  
pp. 235-245 ◽  
Author(s):  
Людмила (Lyudmila) Ивановна (Ivanovna) Тихомирова (Tikhomirova) ◽  
Наталья (Natal'ya) Григорьевна (Grigor'yevna) Базарнова (Bazarnova) ◽  
Татьяна (Tat'yana) Николаевна (Nikolayevna) Ильичева (Ilicheva) ◽  
Юрий (Yuriy) Цатурович (Tsaturovich) Мартиросян (Martirosian) ◽  
Ирина (Irina) Владимировна (Vladimirovna) Афанасенкова (Afanasenkova)
Keyword(s):  
Medicinal Plant ◽  
Nutrient Medium ◽  
Large Scale ◽  
Raw Materials ◽  
Adventitious Shoots ◽  
Biologically Active ◽  
Plant Materials ◽  
Plant Raw Materials ◽  
Intact Plants ◽  
Large Scale Cultivation

Methods of biotechnology allow to obtain high-quality medicinal plant raw materials in a short time, in large quantities without destroying natural reserves. Biotechnological approaches such as aeroponic technologies have the potential for large-scale cultivation of iris plants and production of secondary metabolites. Microclonal reproduction makes it possible to obtain a healthy planting material in the required amount, regardless of the time of year. The combination of these two technological approaches will allow to develop biotechnology of year-round production of medicinal plant raw materials of Siberian iris. The study determined the content of 6-benzylaminopurine on the stage actually micropropagation for the formation of the greatest number of adventitious shoots of optimal length. The required content of BAP in the nutrient medium for I. sibirica was 2.5–5.0 µM. The introduction of cytokinins in the nutrient medium together with auxins, L-glutamine and adenine sulfate 100 mg/l, as well as the alternation of low and high concentrations of cytokinin enhanced the regenerative effect of BAP. With year-round cultivation of regenerative plants in aeroponic conditions, the amount of biomass of plant raw materials I. sibirica for this method was about 31.2 kg / m2 of crude weight in one year. It is established that intact plants and regenerative plants I. sibirica, obtained on the basis of the developed biotechnology, had identical group composition of biologically active substances. It is revealed that the sum of flavonoids in the leaves of hydroponic iris plants exceeded the content in the leaves of intact plants by 3 times, and the content of essential oil in regenerate plants and hydroponic leaves of the Sterch variety but higher by 26% compared with the leaves of intact plants. Aqueous and alcoholic extracts of I. sibirica showed antiviral activity against herpes virus. With low toxicity, both intact plants and regenerative plants had a relatively high selectivity index.

scholarly journals Development of Technology and Composition of the Medicinal Product for Oral Cavity Based on Phytosubstances

2021 ◽  
Vol 10 (4) ◽  
pp. 37-45
Author(s):  
O. N. Abrosimova ◽  
N. S. Pivovarova ◽  
M. A. Burakova ◽  
T. S. Shebitchenko
Keyword(s):  
Citric Acid ◽  
Medicinal Plant ◽  
Oral Cavity ◽  
Raw Materials ◽  
The State ◽  
Technological Properties ◽  
Plant Materials ◽  
Plant Raw Materials ◽  
Wet Masses

Introduction. Treatment and prevention of diseases of the oral mucosa is one of the priority tasks in dentistry. In practice, antibacterial agents are often used in the complex treatment of inflammatory and destructive processes. However, long-term, uncontrolled usage of such drugs leads to numerous complications: drug tolerance, weakening of the therapeutic effect, dysbiosis of the oral cavity and gastrointestinal tract, etc. Therefore, at present, the question of search for alternative to antibiotic therapy remains open. As an alternative, it is necessary considering the usage of effective and safe herbal medicines that are easy to digest, less toxic, practically do not cause side effects and allergic reactions, and have a light regulating and normalizing effect.Aim. The aim of the present study is to develop the composition and technology of effervescent granules for the preparation of a solution for rinsing the oral cavity based on phytosubstances.Materials and methods. Dry extracts were obtained from medicinal plant materials: medicinal sage leaves, medicinal calendula flowers, yarrow herb, medicinal rhizomes and roots and astragalus woolly herb. Sodium carbonate, citric acid, anhydrous, microcrystalline cellulose – 90 (EMCOCEL®90M), povidone (Plasdone™ K-29/32) and calcium stearate were used as auxiliary substances in the granule technology. In laboratory conditions, granules based on phytoextracts were obtained by pressing wet masses. Numerical indicators of medicinal plant raw materials, technological properties of dry extracts and granules, as well as indicators of the quality of granules were determined according to the methods described in the State Pharmacopoeia XIV.Results and discussion. The numerical indicators of medicinal plant raw materials (grinding of raw materials and the content of impurities, total ash in medicinal plant materials and ash insoluble in hydrochloric acid, humidity, content of extractives) were determined and the good quality of the raw materials used in the subsequent stages of drug development was confirmed. Dry extracts from each type of medicinal plant raw materials have been developed and the technological properties of dry extracts have been determined. The composition and technology of effervescent granules by pressing wet masses has been developed. To improve the flowability and reduce the hygroscopicity of the granulated material, microcrystalline cellulose – 90 (EMCOCEL®90M) was used as a filler. To create an effervescent dosage form, citric acid and sodium bicarbonate were added to the granules. The mass for granulation was moistened with a 10% alcohol-water solution of Plasdone™ K-29/32. A draft specification of quality indicators for effervescent granules based on phytoextracts is proposed.Conclusion. In the course of the research work, the numerical indicators of medicinal plant raw materials were determined and its quality was confirmed, which made it possible to use it for further production of dry extracts. The extraction conditions were selected for each type of raw material, dry extracts were developed, and quality indicators were determined in accordance with the requirements of the State Pharmacopoeia XIV. Excipients were selected taking into account the properties of dry extracts, the composition and technology of effervescent granules based on phytoextracts was developed, a draft specification for effervescent granules was proposed in accordance with the requirements of the State Pharmacopoeia XIV.

TECHNOLOGY FOR OBTAINING PECTIN CONCENTRATE FROM ROSEHIP FRUITS

2021 ◽  
pp. 87-90
Author(s):  
М.Ж. Кизатова ◽  
Д.А. Абдуллаева
Keyword(s):  
Medicinal Plant ◽  
Raw Materials ◽  
Raw Material ◽  
Plant Raw Materials ◽  
Plant Raw Material ◽  
Pectin Substances

Статья посвящена важности пектиновых веществ, а также расширению сферы использования лекарственного растительного сырья. В качестве лекарственного растительного сырья представлены технологии получения пектинового экстракта из плодов шиповника, которые встречаются на территории Казахстана 25 видов. Применение пектина в медицине. The article is devoted to the importance of pectin substances, as well as to the expansion of the use of medicinal plant raw materials. As a medicinal plant raw material, technologies for obtaining pectin extract from rosehip fruits, which are found in 25 species on the territory of Kazakhstan, are presented. The use of pectin in medicine

scholarly journals SOLUTION OF THE FUNDAMENTAL TASKS OF DEEP PROCESSING OF PLANT WASTE IN THE RESHETNEV SI-BERIAN STATE UNIVERSITY OF SCIENCE AND TECHNOLOGY

2020 ◽  
pp. 303-308
Author(s):  
Edkham Shukriyevich Akbulatov ◽  
Aleksey Viktorovich Lyubyashkin ◽  
Tat'yana Vasil'yevna Ryazanova ◽  
Yuriy Davydovich Alashkevich ◽  
Elena Vladimirovna Isaeva ◽  
...  
Keyword(s):  
Raw Materials ◽  
Science And Technology ◽  
Scientific Activity ◽  
Chemical Technology ◽  
State University ◽  
Highly Qualified ◽  
Plant Materials ◽  
Plant Raw Materials ◽  
Introductory Article ◽  
Business Structures

A special issue of the journal "Chemistry of Plant Raw Materials" published on the 65th anniversary of the department "Chemical Technology of Wood and Biotechnology", the 90th anniversary of the Siberian State Technological University and the 60th anniversary of the Siberian State Aerospace University. The combination of the two largest and socio-economically significant universities ensured the creation in 2016 of the Reshetnev Siberian State University of science and technology. This is the first supporting university in Eastern Siberia, providing training for highly qualified specialists in more than 100 programs for the forestry, woodworking and chemical industries, aviation and space industry, mechanical engineering, scientific and financial organizations, international and Russian business structures, and the media. The introductory article presents a brief historical excursion, the main directions and prospects of scientific activity of the department “Chemical technology of wood and biotechnology”. They are related to solving the problem of deep complex processing of plant materials with the involvement of modern biological and chemical technologies.

scholarly journals Assessing protopectin transformation potential of plant tissue using a zoned criterion space

2020 ◽  
Vol 8 (2) ◽  
pp. 349-361
Author(s):  
Vladimir Kondratenko ◽  
Tatyana Kondratenko ◽  
Andrey Petrov ◽  
Georgy Belozerov
Keyword(s):  
Boundary Conditions ◽  
Plant Tissue ◽  
Raw Materials ◽  
Water Soluble ◽  
Biologically Active ◽  
Plant Raw Materials ◽  
Criterion Space ◽  
Transformation Potential ◽  
Fragmentation Potential ◽  
Pectin Substances

Introduction. The existing diversity of plant raw materials and products predetermine the prospects of studying their potential as sources of pectin substances. However all current classifications are either fragmented or inconsistent. Study objects and methods. Our theoretical ivestigation aimed to develop an adequate classification for all taxa of plant origin, as well as their tissues and derivatives as pectin-containing materials. We developed criteria for assessing transformation potential of the protopectin complex based on the mass fractions of biologically active non-uronide components, native water-soluble pectin, the protopectin complex, and pectin substances. Individual boundary conditions were based on individual pectin potential, protopectin fragmentation potential, and pectin isolation potential. Results and discussion. Based on the boundary conditions, we defined an universal criterion space that included a set of points M in the coordinates expressed by three main criteria. According to individual boundary conditions, the criterion space was divided, or zoned, into four domains corresponding to protopectin fragmentation potential. They were characterized by: 1) lack of pectin potential, 2) ineffective protopectin fragmentation, 3) ineffective isolation of fragmentation products, and 4) effective isolation. Finally, we developed a generalized algorithm to determine the location of points M[μ1, μ2 , μ3 ] in the zoned criterion space, characterizing the plant tissue. Conclusion. Our approach can be used to assess any plant tissue for its protopectin transformation potential, which determines the technological influence on its pectin potential. This approach is universal, i.e., applicable to both plant tissue and its derivatives.

scholarly journals DEvELopMENT of TEOHNiQuEs FoR THE DETERMiNATioN oF MoisTuRE (Loss oN DRYING) oF MEDiOiNAL PLANT RAW MATERiALS oF MoRPHoLoGiOAL group “FRUiT” by infrared thermogravimetric method

2019 ◽  
Vol 19 (1-2) ◽  
pp. 13-18
Author(s):  
D. A Zhdanov ◽  
V. B Braslavsky
Keyword(s):  
Medicinal Plant ◽  
Russian Federation ◽  
Raw Materials ◽  
The State ◽  
Moisture Loss ◽  
Anethum Graveolens ◽  
Thermogravimetric Method ◽  
Plant Raw Materials ◽  
The Russian Federation

The article is devoted to the development of new and perspective for the State Pharmacopoeia of the Russian Federation (SP RF) techniques for determining of the moisture (loss on drying) of medicinal plant raw materials of the morphological group “Fruit” and medicinal plant preparations by the use of infrared thermogravimetric (IRTGM) method. The techniques for determination of moisture (loss on drying) IRTGM-method as exemplified by the fruit of the following medicinal plants: Silybum marianum (L.) Gaertn., Rosa cinnamomea L. and Anethum graveolens L. were developed. The comparable results for determining of the moisture (loss on drying) of the medicinal plant raw materials of investigated plants were obtained by means of two methods: IRTGM and pharmacopoeial method, which allow us to recommend the developed techniques for inclusion into the relevant monographs of the State Pharmacopoeia of the Russian Federation.

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