Evaluation of GeneXpert for Quantification Viral Load Hepatitis C Virus

Background: GeneXpert has been used for Mycobacterium tuberculosis testing, but is currently available for HCV RNA testing. GeneXpert assay is expected to be more accurate, efficient, and cost-effective for HCV viral load quantification. This study intended to evaluate the new method quantification of plasma HCV RNA by the GeneXpert in comparison to the Roche Cobas TaqMan 96 as standard diagnostic tools.Method: A total of 54 HCV-infected plasma samples with anti-HCV positive were examined by GeneXpert assay, followed with Cobas TaqMan 96 for quantification of HCV RNA. Correlation was performed by Pearson test (in log10) and diagnostic test by Chi-square test. Sensitivity and specificity of the GeneXpert assay measured by calculating 2x2 contingency table. Bland-Altman plot were generated to assess the mean difference between the two assays.Results: GeneXpert has strong correlation to the Roche Cobas TaqMan 96 (R=0.993; P value 0.001). GeneXpert has sensitivity of 100% (95% CI: 90–100%) and specificity of 90% (95% CI: 54.1–99.5%). The Bland Altmand plot showed that one sampel has 1 log difference with the Roche Cobas TaqMan 96 measurement result.Conclusion: There was a strong correlation in the measurement of HCV RNA by GeneXpert and moreover its assay also has an excellent overall performance compared to Cobas TaqMan 96. Thus, it can be considered as a reliable tools for HCV virological response monitoring.

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Impact of Educational Chronic Care Model on Diabetic Patients: A Prospective Cohort Study

10.21203/rs.3.rs-47906/v1 ◽

2020 ◽

Author(s):

Ahmed Mahmoud Elmalky ◽

Abdulsalam S. Alharbi ◽

Abdulkarim M. Alsaqabi

Keyword(s):

Diabetes Education ◽

Clinical Status ◽

Cost Effective ◽

University Hospital ◽

P Value ◽

Diabetic Patients ◽

Management Support ◽

Chi Square ◽

Structured Education ◽

Chi Square Test

Abstract Background Lack of knowledge and understanding about diabetes are important barriers to cure. Treatment of diabetes alone without education is not sufficient. Nowadays, health education could reach us on mobiles. Aim Our aim is how to make advice-giving becomes a system to treat our patients. The theme of this study is diabetes education. And to know how far the prompt well-structured education could affect the clinical status and the quality of life of a poorly controlled diabetic patients. Methods702 patients with type 1 diabetes were followed for 2 years (2017, 2018), by condensed friendly education and training sessions. Our activities were mainly through direct individual approach and social media, structured in the form of visits. The study was done in a specialized clinics of diabetes (SDC) in a tertiary university hospital. We evaluated the clinical status, psychological, sociocultural and satisfaction of the patients, pre and post education. We assessed our patients at the beginning of the study, throughout, and at the time of discharge. Quantitative and qualitative data were compared statistically by paired t test and chi-square test at 0.05 level of significance. Results96.7% of our patients were completely satisfied by what they have achieved through this project. The average HbA1C become less than eight in 54% of patients. Patients with HbA1C 8-9%, BP <140/80, and LDL <3.36 mmol/l, were 46%, 51% and 79% respectively. The average blood pressure for 56% of patients was 132/77. The average LDL level among 71% of patients was 2.25. 27% of patients had average discharged HbA1c of 7.3. Net promotor score of SDC was 85%, were promotors, passives and detractors were 87.8%, 9.5% and 2.8% respectively. P value <0.05Conclusion Education self-management support programs are cost-effective and superior to usual care. Education programs were more effective in lowering HbA1c. Attendees finding it valuable and enjoyable.

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Efficacy of Oral Clonidine as Premedication on Intraoperative Bleeding and Consumption of Inhalational Agent in Patients Undergoing Functional Endoscopic Sinus Surgery

Journal of Pharmaceutical Research International ◽

10.9734/jpri/2021/v33i47a33041 ◽

2021 ◽

pp. 511-516

Author(s):

Vivek Chakole ◽

Shilpa Shankar ◽

Sneha Kota ◽

Jayashree Sen ◽

Sheetal Madavi ◽

...

Keyword(s):

Cost Effective ◽

Sinus Surgery ◽

P Value ◽

Chi Square ◽

Intraoperative Bleeding ◽

Exact Test ◽

Oral Clonidine ◽

Inhalational Agent ◽

Chi Square Test ◽

The Mean

Aim: To study the efficacy of oral clonidine on intraoperative bleeding and consumption of inhalational agent in patients undergoing FESS under general anesthesia. Study Design: Prospective, comparative observational study. Place and Duration of Study: Department of Anesthesiology, AVBRH, from June 2020 to May 2021. Methodology: A total of 30 patients fulfilling inclusion criteria scheduled for FESS were randomly allocated into 2 groups of 15 each; GROUP C (Clonidine group, n=15) who received tab clonidine 5 mcg/kg, 90 minutes before surgery and GROUP M (Multivitamin group, n=15) who received multivitamin tablet. Mean ± standard deviation (SD) or absolute values were used to indicate data; comparison of qualitative data were done using Chi-square test and Fisher’s exact test and quantitative variables using the student ‘t’ Test. P value < 0.05 was taken as statistically significant. Results: Bleeding was considerably less in the group C [1.65 ± 0.4] as compared to group M [2.20 ± 0.6] and is statistically significant [ P value = 0.006]. The mean MAC value (%) of sevoflurane consumption is lesser in the group C [1.25 ±0.25] than the group M [1.30 ±0.20] but not statistically significant (P value = 0.55). The mean dose (microgram) of fentanyl requirement was more in group M [ 120 ±20] than the group C [100 ± 25] and this was statistically significant (P value = 0.02). Conclusion: Oral Clonidine can be used as an excellent premedication and provides cost effective method to attain controlled hypotension as there is lesser requirement of costly inhalational agent and other analgesic drugs. Also, it maintains better hemodynamic stability with fewer side effects.

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Bacteriology and antibiotics treatment of maxillary sinusitis: a prospective study

International Journal of Otorhinolaryngology and Head and Neck Surgery ◽

10.18203/issn.2454-5929.ijohns20174318 ◽

2017 ◽

Vol 3 (4) ◽

pp. 979

Author(s):

Santosh Malashetti ◽

Abhay Havle ◽

Rajesh Karembelkar

Keyword(s):

Maxillary Sinusitis ◽

Cost Effective ◽

Nasal Endoscopy ◽

P Value ◽

Chi Square ◽

X Ray ◽

Chi Square Test ◽

Diagnostic Modalities ◽

A Prospective Study

Background: Sinusitis is one of the commonest causes of patients visit to the otorhinolaryngologist, around one in five cases. The prevalence of sinusitis (146/1000) has been reported. Estimates suggest that clinical condition of sinusitis is more widespread than arthritis and/or hypertension. Sinusitis significantly impacts quality of life, even in comparison to chronic debilitating diseases such as diabetes and congestive heart failure. Sinusitis is the fifth most common medical diagnosis for which antibiotics are prescribed. Sinusitis is usually managed with a 10 days complete course of appropriate sensitive antibiotics. To achieve this goal, there should be some diagnostic modalities which guide towards exact diagnosis as well as safe intervention and cost effective. Over past decade, x-ray paranasal sinuses (Water’s view) and nasal endoscopy have been used successfully as diagnostic modalities in sinus disease.Methods: 100 patients presenting with complaints of sinusitis to the ENT OPD KIMSDU Karad, Maharashtra India were selected randomly (more than 12 yrs of age). All of them were examined clinically and subjected to X -ray PNS (Water’s view) and diagnostic nasal endoscopy [DNE]. Antral lavage was done for all the patients and returning fluid sent for culture and sensitivity. Results were evaluated by statistical analysis using chi square test and evaluating p value tabulated and compared. Appropriate antibiotics were advised orally for 10 days, on the basis of culture reports, such as Amoxcillin-Clavulinate 625 mg BD, Cefpodoxime proxetil 200 mg BD, Levofloxacin 500 mg OD, Ciprofloxacin-Tinidazole (500:600 mg) BD.Results: Majority of the patients were in the age group of 20-29 years (46%) and females (53%). Most common organisms causing maxillary sinusitis was- S.aureus (coagulase+29%). It was found that Amoxicillin-Clavulinate has highest efficacy as compared to other antibiotics.Conclusions: According to our study, most common organisms causing acute maxillary sinusitis in this study are S aureus (coagulase+), S pnemoniae and Enterobacteriacae. Most common organisms isolated are anaerobic Peptostreptococcus, coagulase positive S. aureus and fusobacterium in chronic rhinosinusitis. Efficacy of Amoxicillin-Clavulinic acid was 96% clinically, 94% based on results on DNE findings and 87% by radiological success rate which is statistical more significant than other class of antibiotics. So amoxicillin clavulinic acid can be considered as first line of drug for treating bacterial rhinosinusitis.

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Analisis Faktor Determinan Pelaksanaan Inisiasi Menyusu Dini Oleh Bidan Di Rumah Sakit Umum Anutapura Palu

Jurnal Bidan Cerdas (JBC) ◽

10.33860/jbc.v1i1.87 ◽

2018 ◽

Vol 1 (1) ◽

pp. 34

Author(s):

Ni Nyoman Novita ◽

Gusman Arsyad

Keyword(s):

Emergency Room ◽

Peer Support ◽

Statistical Tests ◽

Bivariate Analysis ◽

P Value ◽

Chi Square ◽

Cross Sectional ◽

Implementation Processes ◽

Chi Square Test ◽

The Government

Implementation of IMD in hospitals has decreased from the previous year and has not reached the target set by the government. Some IMD implementation processes have not been carried out according to applicable standards. So that babies do not get an IMD in accordance with existing SOPs. The purpose of this study was to determine the determinant factors associated with the implementation of the IMD by midwives in the Midwifery and Maternity Room Emergency Room (IGD) at the Anutapura General Hospital in Palu. This research method is analytical with cross sectional approach. The population of this study was that all midwives in the obstetrics emergency room and maternity room at Anutapura Palu Hospital were 37 respondents. The sample in this study is total sampling. The analysis used was univariate, and bivariate analysis using the chi square test with a confidence level of 95% (α = 0.05). The results of statistical tests on variable knowledge of midwives with the implementation of IMD p value: 0.018 (p value <0.05). APN training with the implementation of IMD p value: 0.697 (p value> 0.05). length of work with the implementation of IMD p value: 0.029 (p value <0.05). and peer support with the implementation of IMD p value: 0.007 (p value <0.05). Conclusions there is a relationship between knowledge, length of work, peer support with the implementation of the IMD, and training factors that have nothing to do with IMD implementation. The strongest factor in the relationship is peer support. It is recommended that the Anutarapura Palu Hospital be able to motivate midwives so that they can further enhance their role in the implementation and provide support to their colleagues so that the implementation of the IMD can be carried out in accordance with applicable standards.Keywords: Knowledge, APN Training, Duration of work, Implementation of IMD

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HUBUNGAN ANTARA UMUR IBU DAN JARAK KEHAMILAN DENGAN KEJADIAN PERDARAHAN POSTPARTUM DI RUANG KEBIDANAN RSUD KOTA PRABUMULIH TAHUN 2016

Jurnal Kebidanan : Jurnal Medical Science Ilmu Kesehatan Akademi Kebidanan Budi Mulia Palembang ◽

10.35325/kebidanan.v7i2.115 ◽

2019 ◽

Vol 7 (2) ◽

Author(s):

Desti Widya Astuti Desti Widya Astuti

Keyword(s):

General Hospital ◽

Post Partum ◽

District General Hospital ◽

Study Data ◽

P Value ◽

Chi Square ◽

Cross Sectional ◽

Significance Level ◽

Chi Square Test ◽

Post Partum Bleeding

ABSTRAK Berdasarkan data di RSUD Kota Prabumulih bahwa terdapat peningkatan jumlah kejadian perdarahan post partum, tahun 2014 sebanyak 178 orang, tahun 2015 sebanyak 246 orang dan tahun 2016 sebanyak 151 orang. Penelitian ini bertujuan untuk mengetahui hubungan umur ibu dan jarak kehamilan terhadap kejadian perdarahan post partum di RSUD Kota Prabumulih Tahun 2016. Penelitian ini merupakan penelitian analitik dengan rancangan cross sectional. Populasi yang digunakan adalah semua ibu bersalin di RSUD Kota Prabumulih, sebanyak 1.296 ibu bersalin dan 306 sampel. Pengambilan sampel dengan mengunakan random sampling, analisa data menggunakan analisa univariat dan bivariat dengan menggunakan uji statistik chi-square dengan derajat kemaknaan 0,05. Hasil penelitian ini menunjukan bahwa dari 288 ibu bersalin terdapat 151 yang mengalami perdarahan post partum sebagian besar adalah ibu dengan umur resiko tinggi sebanyak 43 orang (40,9%) dan ibu dengan jarak kehamilan resiko tinggi sebanyak 21 orang (17,3%). Hasil uju chi-square umur didapatkan p.value 0,000 < α 0,05 dan uji chi-square untuk jarak kehamilan didapatkan p.value 0,000 < α 0,05. Maka ada hubungan umur ibu dan jarak kehamilan terhadap kejadian perdarahan post partum di RSUD Kota Prabumulih Tahun 2016. ABSTRACK Based on the data at District General Hospital (RSUD) Prabumulih, there was increasing of post-partum bleeding, in 2014, there were 178 people. In 2015, there were 246 people. And in 2016, there were 151 people. The purpose of the study was to know relationship between maternal mother and the distance and old post-partum bleedingat District General Hospital (RSUD) Prabumulih in 2013. The study was analytic researchwith cross sectional design. Population thas was used in the study was all maternal mother ar District General Hospital (RSUD) Prabumulih. It was about 1.296 maternal mother and from 306. Random sampilng was done in the study, data analyses used univariate and bivariate analyses by using chi-square statistic test with significance level 0,05. The study result showed that from 306 maternal mother, there were 151 mother who experienced old post-partum bleeding, the large of that was high maternal mother 43 people (40,9%) and mother age high distance 21 people (17,3%). The result of chi-square test was p value 0,000 < α 0,05 and chi-square test for age was p value 0,000 < α 0,05. It meant that there was relationship between maternal mother and the distance and of post-partum bleeding at District General Hospital (RSUD) Prabumulih in 2016.

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HUBUNGAN UMUR DAN PARITAS IBU DENGAN KEJADIAN HIPEREMESIS GRAVIDARUM DI RUMAH SAKIT UMUM PUSAT Dr. MOHAMMAD HOESIN PALEMBANG TAHUN 2011

Jurnal Kebidanan : Jurnal Medical Science Ilmu Kesehatan Akademi Kebidanan Budi Mulia Palembang ◽

10.35325/kebidanan.v2i1.23 ◽

2019 ◽

Vol 2 (1) ◽

Author(s):

Wahyu Ida Muliana Wahyu Ida Muliana

Keyword(s):

Pregnant Women ◽

Medical Record ◽

Random Sampling ◽

Hyperemesis Gravidarum ◽

P Value ◽

Chi Square ◽

Cross Sectional ◽

Systematic Random Sampling ◽

Pregnancy And Childbirth ◽

Chi Square Test

ABSTRACT Hyperemesis Gravidarum marked excessive nausea and vomiting in pregnant women at a young age. WHO estimates that 536,000 women died from direct complications of pregnancy and childbirth. One complication of pregnancy is Hyperemesis Gravidarum. Hyperemesis Gravidarum in the world has been estimated to occur in 1-2% of pregnant. According to data from the Medical Record of Dr. Mohammad Hoesin Palembang Hospital, the incidence of Hyperemesis Gravidarum in 2011 there were 72 people of 661 pregnant women. The purpose of this reseach was to determine the relationship between maternal age and parity with Hyperemesis Gravidarum in Dr. Mohammad Hoesin Palembang Hospital 2011. The Design of this reseach used Cross Sectional by analytic approach survey. The population of this reseach are all of mother who gestational ≤ 16 weeks (four months) in the Installation of Obstetrics and Gynecology, Dr. Mohammad Hoesin Palembang Hospital in January to December of 2011 with the sample of 661 people which taken by systematic random sampling and the reseach was conducted from 17 April to 24 April 2012. Each variable that was observed in tests using Chi-Square test with a (0.05). The results of this study showed that 5.9% of mothers with hyperemesis gravidarum, 21.8% of mothers with high risk age, and 30.0% primigravida. Chi-Square test showed no significant relationship between age (p value = 0.000) and parity (p value = 0.000) with the incidence of hyperemesis gravidarum. Expected to the Hospital to be implemented properly instructed how to provide counseling to pregnant women about pregnancy and childbirth, as well as provide confidence that the nausea and vomiting is a symptom of physiology in pregnancy. ABSTRAK Hiperemesis Gravidarum ditandai mual dan muntah yang berlebihan terjadi pada ibu hamil di usia muda. WHO memperkirakan 536.000 perempuan meninggal dunia akibat langsung dari komplikasi kehamilan dan persalinan. Salah satu komplikasi kehamilan adalah Hiperemesis Gravidarum. Insiden Hiperemesis Gravidarum di dunia telah diperkirakan terjadi pada 1-2% wanita hamil. Menurut data dari Medical Record Rumah Sakit Umum Pusat Dr. Mohammad Hoesin Palembang, angka kejadian Hiperemesis Gravidarum pada tahun 2011 terdapat 72 orang dari 661 ibu hamil. Tujuan penelitian ini adalah untuk mengetahui hubungan antara umur dan paritas ibu dengan kejadian Hiperemesis Gravidarum pada ibu di Rumah Sakit Umum Pusat Dr. Mohammad Hoesin Palembang tahun 2011. Desain Penelitian ini menggunakan survei analitik dengan pendekatan Cross Sectional. Populasi penelitian ini adalah dengan umur kehamilan ≤ 16 minggu (4 bulan) yang pernah dirawat inap di Instalasi Kebidanan dan Penyakit Kandungan Rumah Sakit Umum Pusat Dr. Mohammad Hoesin Palembang pada bulan Januari-Desember tahun 2011 dengan jumlah sample 661 orang yang diambil secara systematic Random Sampling (secara acak sistematis) dan penelitian ini dilakukan dari tanggal 17 April sampai dengan 24 April 2012. Masing-masing variabel yang diteliti di uji dengan menggunakan uji Chi-Square dengan a (0,05). Hasil penelitian ini menunjukkan bahwa 5,9% ibu mengalami hiperemesis gravidarum, 21,8% ibu dengan umur resiko tinggi, dan 30,0% ibu primigravida. Uji Chi-Square menunjukkan ada hubungan yang bermakna antara umur (p value = 0,000) dan paritas (p value = 0,000) dengan kejadian hiperemesis gravidarum. Diharapkan dapat menjadi masukan bagi pihak Rumah Sakit agar dilaksanakan penyuluhan dengan cara memberikan konseling terhadap ibu hamil tentang kehamilan dan persalinan, serta memberikan keyakinan bahwa mual muntah merupakan gejala fisiologi pada kehamilan.

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Hubungan Pola Asuh Orang Tua Terhadap Perkembangan Sosial Anak Usia 4-6 Tahun Di Tk Dharma Wanita Gumukmas Tahun 2011

Jurnal Ilmiah Kesehatan ◽

10.35952/jik.v1i2.79 ◽

2012 ◽

Vol 1 (2) ◽

Author(s):

Wahyu Widayati

Keyword(s):

P Value ◽

Chi Square ◽

Chi Square Test

Pola asuh orang tua adalah pola perilaku yang diterapkan pada anak dan bersifat relative konsisten dari waktu ke waktu. Dimana salah satu faktor yang mempengaruhi perkembangan sosial anak adalah cara mendidik anak dalam keluarga (pola asuh). Penelitian ini bertujuan untuk mengetahui hubungan pola asuh orang tua terhadap perkembangan sosial anak usia 4-6 tahun di TK Dharma wanita Gumukmas Tahun 2011. Desain penelitian yang digunakan adalah penelitian deskriptif korelasi dengan populasi orang tua murid di TK Dharma wanita Gumukmas. Pengambilan sampel dengan total sampling sebanyak 95 responden. Pengumpulan data untuk mengetahui pola asuh oang tua dan perkembangan sosial anak dengan menggunakan koesioner. Analisanya yaitu univariat dan bivariat. Uji statistik yang digunakan chi square test dengan derajat kemaknaan p>0,05. Hasil penelitian menunjukkan bahwa tidak ada hubungan yang bermakna antara pola asuh orang tua dengan perkembangan sosial anak usia 4-6 tahun di TK Dharma wanita Gumukmas dengan p value 0,008. Berdasarkan hasil penelitian tersebut, diharapkan perlunya pemahaman tentang metode pemberian pola asuh yang efektif bagi anak karena ini sangat penting untuk perkembangan sosial anak

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Hubungan Status Gizi Dengan Proses Penyembuhan Luka Di Rsud H. Andi Sulthan Daeng Radja Kabupaten Bulukumba

Jurnal Kesehatan Panrita Husada ◽

10.37362/jkph.v2i1.147 ◽

2017 ◽

Vol 2 (1) ◽

pp. 20-28

Author(s):

Fitriani ◽

Tenriwati

Keyword(s):

Wound Healing ◽

Nutritional Status ◽

Healing Process ◽

Data Retrieval ◽

Observational Research ◽

Wound Healing Process ◽

P Value ◽

Chi Square ◽

Cross Sectional ◽

Chi Square Test

At present, the incidence of injuries in Indonesia is quite high, as seen from data on traffic accidents in the general public. There are several factors that affect wound healing, one of which is nutritional status. Based on the preliminary data retrieval conducted by researchers in the seruni surgery room in the last 1 month namely in March, it was found that the number of wounded patients was 109 patients, where the number of men was 78 (71.56%) while the number of women was 31 ( 28.44%) The purpose of this study was to determine the relationship between nutritional status and the wound healing process in RSUD. H. Andi. Sulthan Daeng Radja Kab. Bulukumba. This research uses the type of design of this research is quantitative research. This type of research uses analytic observational research with cross sectional approach. The sample of this study were 41 respondents taken by purposive sampling method. Data analysis in this study used the chi-square test (chi square test). The results of the analysis used the chi-square statistical test with a confidence level (α = 0.05). Based on the results of this test, the p value is 0.001, thus p <α (0.001 <0.05), then Ho is rejected and Ha is accepted. The conclusion of this study is that there is a relationship between nutritional status and the process of wound healing in RSUD. H. Andi. Sulthan Daeng Radja Kab. Bulukumba. Researchers suggest that this study be used as a material consideration in the fulfillment of nutrition in wound care patients in RSUD.H.A. Sulthan Daeng Radja Kab. Bulukumba and this research can be continued by conducting research related to the wound healing process and linking it with other variables.

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Relationship of Workload and Double Role With Work Fatigue on Batik Craftsmen

Jurnal Endurance ◽

10.22216/jen.v4i2.4013 ◽

2019 ◽

Vol 4 (2) ◽

pp. 293

Author(s):

Herdianti Herdianti ◽

Tatik Maryana

Keyword(s):

Data Analysis ◽

Quantitative Research ◽

Sampling Technique ◽

Work Load ◽

Dual Role ◽

P Value ◽

Chi Square ◽

Cross Sectional ◽

Chi Square Test ◽

Almost All

Background: In Batik Mawar, almost all work is done manually using the hands and upper arms on a continuous basis combined with the rigor of work and the use of traditional tools. The work has a heavy workload because all the work process is done by the same craftsman causing fatigue besides that the worker also have double role. The purpose of this study is to determine the relationship between workload and dual role with feelings of fatigue on craftsmen batik roses.Method: This research is Quantitative research with Cross Sectional research design. The population in this study are all artisans in Batik Mawar. Sampling in this study using total sampling technique with the number of research samples as many as 40 respondents. Data analysis used by Univariat and Bivariat.Result: Result of data analysis using Chi-Square test for work load got value p-Value = 0,001. The result of data analysis using Chi-square test for double role got p-value = 0,031. Thus it is concluded that there is a meaningful relationship between workload and dual role with feeling tired. We recommend that craftsmen wash clothes 2 times a day, cook ready meals, other than together in completing the work at home Di Batik Mawar, hampir semua pekerjaan dikerjakan secara manual menggunakan tangan dan lengan atas secara berkesinambungan yang dikombinasi dengan ketelitian kerja dan penggunaan alat-alat tradisional. Pekerjaan mempunyai beban kerja yang berat dikarenakan semua proses kerja dilakukan oleh pengrajin yang sama sehingga menimbulkan kelelahan disamping itu pekerjanya juga memiliki peran ganda. Tujuan penelitian ini adalah untuk mengetahui hubungan beban kerja dan peran ganda dengan perasaan lelah pada pengrajin batik mawar.Metode: Penelitian ini merupakan penelitian Kuantitatif dengan desain penelitian Cross Sectional. Populasi dalam penelitian ini adalah semua pengrajin di Batik Mawar. Pengambilan sampel pada penelitian ini menggunakan teknik total sampling dengan jumlah sampel penelitian sebanyak 40 responden. Analisis data yang digunakan Univariat dan Bivariat.Hasil: Hasil analisis data yang menggunakan uji Chi-Square untuk beban kerja didapatkan nilai p-Value = 0,001. Hasil analisis data yang menggunakan uji Chi-square untuk peran ganda didapatkan nilai p-value= 0,031. Dengan demikian disimpulkan bahwa ada hubungan yang bermakna antara beban kerja dan peran ganda dengan perasaan lelah.Sebaiknya pengrajin mencuci pakaian 2 kali sehari, memasak makanan siap saji, selain itu dengan cara bersama-sama dalam menyelesaikan pekerjaan dirumah.

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Haemoconcentration as a predictor of severity in acute pancreatitis

Journal of Kathmandu Medical College ◽

10.3126/jkmc.v4i1.15020 ◽

2016 ◽

Vol 4 (1) ◽

pp. 3-7

Author(s):

Tanka Prasad Bohara ◽

Dimindra Karki ◽

Anuj Parajuli ◽

Shail Rupakheti ◽

Mukund Raj Joshi

Keyword(s):

Acute Pancreatitis ◽

Pearson Correlation ◽

Characteristic Curve ◽

Scoring Systems ◽

Cost Effective ◽

Receiver Operator Characteristic Curve ◽

First Episode ◽

P Value ◽

Receiver Operator Characteristic ◽

Chi Square

Background: Acute pancreatitis is usually a mild and self-limiting disease. About 25 % of patients have severe episode with mortality up to 30%. Early identification of these patients has potential advantages of aggressive treatment at intensive care unit or transfer to higher centre. Several scoring systems are available to predict severity of acute pancreatitis but are cumbersome, take 24 to 48 hours and are dependent on tests that are not universally available. Haematocrit has been used as a predictor of severity of acute pancreatitis but some have doubted its role.Objectives: To study the significance of haematocrit in prediction of severity of acute pancreatitis.Methods: Patients admitted with first episode of acute pancreatitis from February 2014 to July 2014 were included. Haematocrit at admission and 24 hours of admission were compared with severity of acute pancreatitis. Mean, analysis of variance, chi square, pearson correlation and receiver operator characteristic curve were used for statistical analysis.Results: Thirty one patients were included in the study with 16 (51.61%) male and 15 (48.4%) female. Haematocrit at 24 hours of admission was higher in severe acute pancreatitis (P value 0.003). Both haematocrit at admission and at 24 hours had positive correlation with severity of acute pancreatitis (r: 0.387; P value 0.031 and r: 0.584; P value 0.001) respectively.Area under receiver operator characteristic curve for haematocrit at admission and 24 hours were 0.713 (P value 0.175, 95% CI 0.536 - 0.889) and 0.917 (P value 0.008, 95% CI 0.813 – 1.00) respectively.Conclusion: Haematocrit is a simple, cost effective and widely available test and can predict severity of acute pancreatitis.Journal of Kathmandu Medical College, Vol. 4(1) 2015, 3-7

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