scholarly journals Proximate Composition, Mineral Content and Secondary Metabolites of Three Medicinal Wild Fagonia Species

Food Biology ◽  
2020 ◽  
pp. 1-6
Author(s):  
Mustafa M. El-Zayat ◽  
Yasser Ahmed El-Amier ◽  
El-Sayed F. El-Halawany ◽  
Iman A. Abo Aisha
Keyword(s):  
Secondary Metabolites ◽  
Proximate Composition ◽  
Nutritional Value ◽  
Mineral Content ◽  
Total Phenolics ◽  
Methanolic Extract ◽  
Phytochemical Composition ◽  
Total Alkaloids ◽  
Aerial Parts ◽  
Micro Elements

Proximate composition of the aerial parts of three Fagonia species (Fagonia arabica L., F. mollis Delile and F. cretica L.) collected from different habitats were analyzed. Macro- and micro-elements as well as some secondary metabolites were estimated. The obtained results revealed that F. creticus contains appreciable levels of nutritive components considering that its nutritional value (351.06 kcal/100g dry wt.) was remarkably higher than that of F. arabica and F. mollis (327.99 and 293.07 kcal/100g dry wt., respectively). The concentration of Na was relatively the highest among the other estimated macroelements in the studied species followed by K, Ca and Mg, respectively while Fe was the highest microelement followed by Cu, Mn and Zn, respectively. The phytochemical composition revealed that methanolic extract of F. creticus was the richest in total alkaloids and flavonoids, while F. arabica found to be the richest in total phenolics and tannins.

scholarly journals Extraction, Qualitative and Quantitative Determination of Secondary Metabolites of Aerial Parts of Clematis heynei and Solanum virginianum

2019 ◽  
Vol 9 (1-s) ◽  
pp. 260-264
Author(s):  
Pravin Morankar ◽  
Alok Pal Jain
Keyword(s):  
Quantitative Analysis ◽  
Secondary Metabolites ◽  
Total Phenolics ◽  
Developed Countries ◽  
Aluminium Chloride ◽  
Phytochemical Analysis ◽  
Test Protocol ◽  
Aerial Parts ◽  
Pharmaceutical Industries ◽  
Phenolics Content

The increasing interest in powerful biological activity of secondary metabolites outlined the necessity of determining their contents in medicinal plants. In the last few years, there has been an exponential growth in the field of herbal medicine and gaining popularity both in developing and developed countries because of their natural origin and less side effects. Clematis heynei (C. heynei, Ranunculaceae) is commonly known as Deccan clematis, Murhar, Morvel, Ranjaee and it is a somewhat woody climber very sparsely distributed in deciduous forests of Western Ghats, India. In the Indian system of medicine ‘Ayurveda’ this plant is used to eliminate malarial fever and headache. Different plant parts were used for treating various diseases. Solanum virginianum L. (S. virginianum, Solanaceae, Solanum xanthocarpum Schrad. & H. Wendl.) is a diffuse and very prickly under shrub. It is found growing commonly in various regions of the world on sandy soils and is distributed throughout India. The plant is used traditionally to treat asthma, chest pain, leucoderma, scorpion bite, and sterility in women. The aim of the present study is to examine C. heynei and S. virginianum aerial parts of plant for phytochemical profile. Qualitative analysis of various phytochemical constituents and quantitative analysis of total phenolics and flavonoids were determined by the well-known test protocol available in the literature. Quantitative analysis of phenolic and flavonoids was carried out by Folins Ciocalteau reagent method and aluminium chloride method respectively. Phytochemical analysis revealed the presence of phenols, flavonoids, tannins, saponins, alkaloids, fixed oil and fats. The total phenolics content of methanolic and aqueous extract of C. heynei was (0.592, 0.292 mg/100mg), followed by flavonoids (1.371, 0.723mg/100mg) respectively. The total phenolics content of methanolic extract of S. virginianum was (0.345mg/100mg), followed by flavonoids (0.978mg/100mg). The present study concluded that the crude extract of C. heynei and S. virginianum is a rich source of secondary phytoconstituents which impart significant antioxidant potential. The findings of the present study will be helpful to phytochemists, pharmacologists and pharmaceutical industries.  

scholarly journals Pharmacological and Phytochemical Evaluation of Calendula officinalis Linn. For Anti-Anxiety Activity

2017 ◽  
Vol 9 (1) ◽  
Author(s):  
Rani Anita ◽  
Mohan Chander
Keyword(s):  
Methanol Extract ◽  
Elevated Plus Maze ◽  
Methanolic Extract ◽  
Calendula Officinalis ◽  
Traditional Use ◽  
Total Alkaloids ◽  
Aerial Parts ◽  
Plus Maze ◽  
Anxiety Screening ◽  
Chloroform Methanol

The Plant Calendula officinalis Linn. (Asteraceae), traditionally was found to be used in the treatment of anxiety. Despite a long tradition of use, no systematic pharmacological and phytochemical work has been carried out on this plant. Thus, C. officinalis was subjected to preliminary anti-anxiety screening studies, with a view to ascertain the truth on evidence of its traditional use as anti-anxiety. In the present study, aerial parts of the plant were extracted using solvents in the order of increasing polarity, viz., petroleum ether (60–80°C), chloroform, methanol and distilled water. Elevated plus maze (EPM) was used to evaluate the anti anxiety activity on all the crude extracts on mice. Methanolic extract of C. officinalis at the dose of 100 mg/kg, p.o. was found significant when compared to diazepam, (2mg/kg). Phytochemical screening showed the presence of alkaloids and polyphenols therefore specific methods are used to extract the total alkaloids and polyphenols fractions from the plant material and methanol extract. Polyphenol fraction at the dose of 50 mg/kg, p.o. showed significant anti-anxiety activity.

scholarly journals Isolation of Daphnetin 8-methyl ether from Daphne oleoides and its Anti-bacterial activity

2015 ◽  
Vol 4 (4) ◽  
pp. 224-226
Author(s):  
Muhammad Younus Dar ◽  
◽  
Tabassum Ara ◽  
Seema Akbar ◽  
◽  
...  
Keyword(s):  
Secondary Metabolites ◽  
Benzoic Acid ◽  
Methyl Ether ◽  
13C Nmr ◽  
Methanolic Extract ◽  
Bacterial Activity ◽  
Moderate Activity ◽  
Aerial Parts ◽  
The World

The aim of the present work was to isolate and identify secondary metabolites of Daphne oleoides, which was not phytochemically analysed in this important geographical region of the world until now, followed by the determination of anti-bacterial activity. An important plant coumarin daphnetin 8-methyl ether (1)[7-hydroxy8-methoxy coumarin] not previously reported from this species was isolated from the methanolic extract of aerial parts of Daphne oleoides, along with already reported 4-ethoxy benzoic acid (2)and 4-hydroxy benzoic acid(3) by repeated column chromatography. The structures of these compounds were elucidated on the basis of 1H, 13C NMR and MS analysis. The compound 1 was evaluated for its anti-bacterial potential which showed moderate activity.

scholarly journals Secondary Metabolites from Asperula lutea subsp. rigidula

2011 ◽  
Vol 6 (2) ◽  
pp. 1934578X1100600
Author(s):  
Olga Tzakou ◽  
Konstantinos Lempesis ◽  
Anargyros Loukis
Keyword(s):  
Fatty Acids ◽  
Linoleic Acid ◽  
Secondary Metabolites ◽  
Palmitic Acid ◽  
Chlorogenic Acid ◽  
Methanolic Extract ◽  
Polar Fraction ◽  
Ethyl Esters ◽  
Endemic Plant ◽  
Aerial Parts

From the aerial parts of Asperula lutea subsp. rigidula (Halacsy) Ehrend., an endemic plant of southeastern Greece, nine known compounds, β-sitosterol, geniposidic acid, deacetyl-asperuloside, scandoside, chlorogenic acid, quercetin, hyperin, isoquercitrin and rutin, were isolated. From the analysis of a non polar fraction of the methanolic extract by means of GC and GC-MS, eighteen compounds were identified, mainly esters of fatty acids. The major components were the ethyl esters of palmitic acid (32.7%), linolenic acid (20.1%) and linoleic acid (10.5%).

HEPATOPROTECTIVE AND ANTIOXIDANT ACTIVITY OF METHANOLIC EXTRACT OF CISSUS PALLIDA

INDIAN DRUGS ◽  
2014 ◽  
Vol 51 (10) ◽  
pp. 29-37
Author(s):  
A. Tamil Selvan ◽  
◽  
Ruman Yezdhani ◽  
M. Rama Devi ◽  
N. Siva Subramanian ◽  
...  
Keyword(s):  
Antioxidant Activity ◽  
Secondary Metabolites ◽  
Liver Diseases ◽  
Total Phenolics ◽  
Methanolic Extract ◽  
Hepatoprotective Activity ◽  
Total Flavonoids ◽  
Skin Disorders ◽  
Cns Disorders ◽  
Ft Ir

Cissus pallida is used traditionally to treat various ailments like liver diseases, ulcer, wounds, skin disorders, CNS disorders, management of diabetes etc. In this present investigation, hepatoprotective activity was done in stem and wood parts of methanolic extract of Cissus pallida at the doses of (200mg/kg, 400 mg/kg) by paracetamol induced hepatotoxicity. The results obtained on 14th day and after 28 days was significant (p by FT-IR. Secondary metabolites like total flavonoids, total phenolics, tannins and alkaloids were estimated. The findings proves that the plant Cissus pallida shows hepatoprotective and antioxidant activity.

Secondary metabolites from the aerial parts of Stachys tetragona, a Greek endemic species

Planta Medica ◽  
2012 ◽  
Vol 78 (11) ◽  
Author(s):  
A Afouxenidi ◽  
T Milošević-Ifantis ◽  
H Skaltsa
Keyword(s):  
Secondary Metabolites ◽  
Endemic Species ◽  
Aerial Parts

α-Glucosidase Inhibition and Docking Studies of 5-Deoxyflavonols and Dihydroflavonols Isolated from Abutilon pakistanicum

2019 ◽  
Vol 23 (17) ◽  
pp. 1857-1866
Author(s):  
Munawar Hussain ◽  
Zaheer Ahmed ◽  
Shamsun N. Khan ◽  
Syed A. A. Shah ◽  
Rizwana Razi ◽  
...  
Keyword(s):  
Methanolic Extract ◽  
Docking Studies ◽  
Hydroxyl Group ◽  
Coumaric Acid ◽  
In Vitro Activity ◽  
Aerial Parts ◽  
First Time ◽  
Acid Esters ◽  
Phenol Moiety

Three new 5-deoxyflavonoid and dihydroflavonoids 2, 3 and 4 have been isolated from the methanolic extract of Abutioln pakistanicum aerial parts, for which structures were elucidated explicitly by extensive MS- and NMR-experiments. In addition to these, 3,7,4′-trihydroxy-3′-methoxy flavonol (1) is reported for the first time from Abutioln pakistanicum. Compound 2 and 4 are p-coumaric acid esters while compounds 2–4 exhibited α-glucosidase inhibitory activity. Docking studies indicated that the ability of flavonoids 2, 3 and 4 to form multiple hydrogen bonds with catalytically important residues is decisive hence is responsible for the inhibition activity. The docking results signified the observed in-vitro activity quite well which is in accordance with previously obtained conclusion that phenol moiety and hydroxyl group are critical for the inhibition of α-glucosidase enzyme.

Investigating the Antioxidant Potential of Garlic (Allium sativum) Extracts Through Different Extraction Modes

2019 ◽  
Vol 15 (1) ◽  
pp. 45-50 ◽  
Author(s):  
Kanza A. Awan ◽  
Masood S. Butt ◽  
Iahtisham Ul Haq ◽  
Hafiz A.R. Suleria
Keyword(s):  
Allium Sativum ◽  
Total Phenolics ◽  
Methanolic Extract ◽  
Antioxidant Potential ◽  
Flavonoid Content ◽  
Time Intervals ◽  
Methanolic Extracts ◽  
Maximum Extraction ◽  
Acid Potential ◽  
The Ideal

Background: Garlic (Allium sativum) possesses health enhancing abilities due to the presence various phytoceutics moities. The current research was deigned to explore the phytochemicals and antioxidant capacity of Pakistani garlic. Methods: Garlic extracts were obtained using methanol, hexane and ethyl acetate at different time intervals (35, 50 and 65 min) followed by their polyphenols and flavonoid content determination. Afterwards, the antioxidant potential was also determined. Results: The outcomes revealed that the methanolic extracts obtained at 50 min extraction time showed maximum total phenolics as 60.38±0.23 mg GAE/100g and flavonoids as 58.45±1.24 mg/100g. Similarly, the highest DPPH activity (61.59±1.58%) and β-carotene and linoleic acid potential (64.96±1.72%) were also observed for methanolic extract. Conclusion: Inferences were made that Pakistani garlic contains myriad of phenolics and flavonoids but the extraction of these components depends upon the solvent/time combination. In this study, methanol proved to be the ideal solvent for the maximum extraction of phytochemicals from garlic.

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