scholarly journals Correlation Between HCV Infection and Creatinine Level in Thalassemia Patents

2020 ◽  
Vol 10 (01) ◽  
pp. 164-169
Author(s):  
Saif Jabbar Yasir ◽  
Saif Yassen Hassan

The current study aimed to fine the relationship between hepatitis C virus (HCV), and kidney impairment in thalassemia patient. This retrospective case-control study include sample size total number 102 patients ranged between 15 and 30 years were divided into two groups: first, 51patients suffering from kidney impairment - the kidney impairment detected by creatinine level in serum and second, 51-patient without kidney impairment as a control group. Both group monitored HCV infection. The patient attended to AL-Zahra hospital (Najaf) thalassemia department from January to Aug 2018. Biochemical test use for detection of creatinine, serological test use for detection HCV. The SPSS program version 24 uses for data analysis the results. When observed the results in both groups the percentage of HCV in the first group (with abnormal creatinine level) is higher than in the second group (with normal creatinine level). 32/51 (62, 7%) and 19/51(37, 2%) respectively. A high level of HCV in a group with kidney defect indicates for viral effect on the normal kidney function, kidney defect patient of thalassemia patient has a higher susceptibility to HCV infection.

Author(s):  
Mahmut Atum ◽  
Gürsoy Alagöz

Purpose: This study aimed to compare the neutrophil-to-lymphocyte (NLR) and plateletto- lymphocyte (PLR) ratios in patients with retinal artery occlusion (RAO) with those from a healthy control population and to identify the relationship between them. Methods: Forty-six patients with RAO and fifty-one healthy control subjects were included in this retrospective case-control study. RAO was diagnosed following an ophthalmic examination and fluorescein angiography (FA). Blood neutrophil, lymphocyte, and platelet counts were recorded for each of the 97 subjects, from which NLR and PLR values were calculated. Results: There were 46 patients (28 male [M], 18 female [F]) in the RAO group and 51 patients (27 M, 24 F) in the control group. No significant differences were found between patients with RAO and the control subjects in terms of gender and age (P > 0.05). Patients with RAO had significantly increased NLR values (2.85 ± 1.70) than the control subjects (1.63 ± 0.59, P < 0.001). The mean PLR in patients with RAO was 123.69 ± 64.98, while that in control subjects was 103.08 ± 36.95; there was no significant difference between the two groups (P = 0.055). A logistic regression analysis revealed that NLRs were 3.8 times higher in patients with RAO than in control subjects (odds ratio = 3.880; 95% confidence interval = 1.94 to 7.74; P < 0.001). Conclusion: NLRs were significantly increased in patients with RAO compared to the control subjects.


BJPsych Open ◽  
2021 ◽  
Vol 7 (S1) ◽  
pp. S299-S299
Author(s):  
Hemma Velani ◽  
Julia Gledhill

AimsTo systematically review Psychological and Behavioural treatments on NES in children and adolescents by reviewing the current literature.BackgroundNon-epileptic seizures (NES) are associated with a high level of functional impairment for young people and their families. However, there are no UK guidelines for the management of NES in children and adolescents or adults. Though information from the limited studies in adults may be useful, the findings may not be generalizable to children and adolescents. To date, we are unaware of any published systematic review on this topic in children and adolescents.MethodA systematic search of relevant electronic databases was conducted. Any study investigating the effectiveness of psychological and behavioural treatments on NES, in Children and Adolescents was included.ResultFifteen studies were identified, but only six studies had the primary aim of evaluating an intervention, and only one used a control group. The rest were observational studies that examined retrospective case notes.CBT and psychoeducation were identified as the most common interventions. Eleven out of the fifteen studies used multiple treatments, four looked at one treatment only, three of these CBT and one was a natural history study.Where individual therapy was provided, a common focus was management of anxiety, usually delivered in a flexible way, adapted to individual needs. Despite being identified as important in the literature, only one study demonstrated care that involved collaboration between physical and mental health teams.ConclusionIt's difficult to conclude from this review that one treatment approach is superior to another. The findings of this review offer some insight into current practise and may help to inform future research in this area. CBT and psychoeducation with a focus on anxiety are frequently included in interventions for NES in young people, and further evaluation of these treatment modalities could be a helpful next step.


2003 ◽  
Vol 70 (2) ◽  
pp. 157-164 ◽  
Author(s):  
Petra Winter ◽  
Franz Schilcher ◽  
Klemens Fuchs ◽  
Ian G Colditz

The responses of five lactating East Friesian milk ewes to experimental mammary infection with Staphylococcus epidermidis and of five control ewes were examined over a period of 10 weeks. Infection caused an influx of neutrophils into milk, the numbers of which started to rise 4 h post infection and peaked 24 h after infection. The initial response was accompanied by mild fever and mild leucopaenia in blood (8 h after infection). No other signs of systemic infection were observed. Milk appeared normal at all times, although the milk yield of infected ewes tended to decline. Staphylococci were absent in milk from four ewes at 2 d and at 3 d after infection, but re-emerged intermittently in four of five ewes at subsequent samplings. Cytokines in milk were measured by ELISA. IL-8 was elevated in infected glands at 2 h and peaked at 8 h. In the four ewes intermittently shedding bacteria, IL-8 remained elevated until the final sampling at 10 weeks. IL-1β was transiently elevated at 1 d and 2 d and showed a pronounced peak in one sheep. Milk samples from this ewe were bacteriologically negative, somatic cell count (SCC) was within the normal range and the concentrations of IL-1β, as well as IL-8, were similiar to the control group (n=5) from 1 week after infection until the final sampling. Histological examination revealed leucocytic infiltrates in the four glands remaining infected at the end of the experiment, and a high level of CD5+ lymphocytes in three ewes. The results suggest that the relationship between the initial neutrophil influx and the proinflammatory cytokines may be responsible for determining the course of infection. Subclinical mastitis due to coagulase-negative staphylococci leads to minor changes in milk yield and milk constituents.


Author(s):  
Hananjassim Hammod ◽  
Thanaa Abdulmahdi Mokif ◽  
Hussein Jasim Al-harbi

Objective: This study aimed to evaluate the relationship between thalassemia disease and body mass index (BMI) and the correlation with blood group of thalassemia patients.Methods: The study includes 260 persons (male+female), 200 persons were thalassemia patient (120 male and 80 female), and 60 healthy persons (30 male and 30 female) as control group; furthermore, people were divided into three group according to age 1–9, 10–19, and >20 years, and BMI and blood group were measured for all patients and healthy people.Results: The results showed that the frequency of thalassemia in male (65%) is higher than in female (40%); as well as, the results showed that the age group (10–19) years is more frequent in male, while in female, the age group (1–9) years is more frequent. The results of BMI revealed a significant decrease (p<0.05) in all groups of thalassemia patients compared with healthy group; as well as, the results of blood group showed that the group (O+) is the more frequent 34% in comparison with the other blood groups.Conclusion: We conclude that there was a strong relationship among gender, blood group (the most common blood group observed is O +ve), and BMI with thalassemia.


2019 ◽  
Vol 10 (2) ◽  
pp. 36-43
Author(s):  
Kholilah Samosir ◽  
Eustasia Eustasia

Pneumonia is one of the largest contributors to health problems and causes of death of children under five years old. Jatibarang health centre is one of the health centers in the Indramayu regency with the incidence of pneumonia at most each year. According to data from the clinic there were 907 cases of pneumonia in infants aged 1-4 years. Data in 2013 as many as 737 cases. The study aims to analyze the relationship between physical environmental factors and family practice with the incidence of pneumonia in children under five years old in Puskesmas Jatibarang Indramayu regency. This study is a retrospective case-control study method. As the case group and the control group 71 respondents. Analysis of data using univariate, bivariate, and mulivariate analyzes. The results were obtained from 11 variables examined, the variables associated with the incidence of pneumonia is the lighting in the room (p = 0.030 OR 6.080 95% CI 1.193 - 30.978), the lighting in the family room (p = 0.030 OR 10.669 95% CI 1.254 - 90.728) and open the window every day (p = 0.016 OR 2.709 95% CI 1.200 - 6.116). It can be concluded there is a relationship between the lighting in the room, the lighting in the living room with the incidence of pneumonia.   Keywords : Pneumonia, children under five years old, physical environment factor, Indramayu


Animals ◽  
2021 ◽  
Vol 11 (8) ◽  
pp. 2298
Author(s):  
Kamila Puppel ◽  
Patrycja Staniszewska ◽  
Marcin Gołębiewski ◽  
Jan Slósarz ◽  
Grzegorz Grodkowski ◽  
...  

A negative energy balance alters the concentration of various fractions of cows’ milk. Therefore, by analyzing the concentration of individual proteins in milk, it is possible to indirectly monitor the health of the animal. The aim of the present study was to identify the relationship between the concentrations of blood β-hydroxybutyric acid (BHBA) and whey proteins in milk as a marker for the diagnosis of metabolic diseases. The analysis included milk and blood samples from 95 Holstein-Friesian cows, which were divided into three groups that were differentiated in terms of serum BHBA levels 5–7 days post-calving: LBHBA, low level of BHBA: 0.200–0.500 mmol/L; NBHBA, optimal level of BHBA- control group: 0.500–1.200 mmol/L; HBHBA, high level of BHBA: >1.200 mmol/L. Concentrations of α-lactoalbumin in the milk after 7 days of lactation proceeded in accordance with the concentration of β-hydroxybutyric acid, as follows: LBHBA > NBHBA > HBHBA. Concentrations of β-lactoglobulin in milk after 14 days of lactation proceeded in accordance with the concentration of β-hydroxybutyric acid, as follows: LBHBA < NBHBA < HBHBA. Therefore, it can be concluded that whey proteins can be used as non-invasive markers for diagnosing metabolic diseases. A high concentration of β-lactoglobulin can be a marker for diagnosing ketosis. Conversely, elevated levels of α-lactalbumin may indicate the occurrence of a metabolic disorder, such as acidosis.


2021 ◽  
pp. 027623662110053
Author(s):  
Osman Görkem Çetin ◽  
Metehan Irak

Previous research has provided evidence for a relationship between illusory pattern perception and irrational beliefs. A common assumption is illusory pattern perception increases with an increasing feeling of lack of control. Delusion-like experiences include some of the behaviors related to irrational beliefs. Since no direct association between DLE and illusory pattern perception has been established, in this study we investigated the relationship between delusion-like experiences and illusory pattern perception for images with visual noise in a condition in which the participants were manipulated to lack control while controlling for another assumption which is jumping to conclusions bias on a bead task is predicted by delusion-like experiences. Results showed participants with delusion-like experiences produced more illusory pattern perception and false positive recognition for visually ambiguous stimuli. Participants who were manipulated to lack control produced more false positive recognition than the control group. A high level of delusion-like experiences predisposes vulnerability for increasing pattern seeking behavior under lack of control manipulation.


2021 ◽  
Vol 21 (68) ◽  
Author(s):  
Omar Gonzalez ◽  
Elisabeth Ramos Rodríguez ◽  
Patricia Vásquez Saldías

Las aplicaciones tecnológicas ofrecidas para la educación son variadas, brindando nuevas posibilidades de aprendizaje. Se debe estar en constante vigilancia de las propuestas de gamificación para el aula, dado que su desarrollo y uso no asegura un éxito en la enseñanza. Estudiamos el impacto de la gamificación en la enseñanza de la matemática, analizando su papel en el tratamiento de las figuras geométricas cono y cilindro con estudiantes de 13 y 14 años. Desde un enfoque cuantitativo descriptivo de tipo cuasi-experimental, con grupo control y piloto y aplicación de test, se realiza un análisis estadístico clásico e implicativo, evidenciando un mayor porcentaje de respuestas correctas del grupo piloto, en el ítem sobre la relación entre el volumen del cono y el cilindro, con un 96,3%, en contraste un 73,08% que obtuvo el grupo control. Además, se muestra un comportamiento con alto nivel de similaridad (84,4%) entre el uso del videojuego y responder satisfactoriamente los ítems. Esto nos sugiere que este medio educativo puede provocar mejoras en los aprendizajes del alumnado, quien parece ser proclive a su uso. The technological applications offered for education are varied, providing new learning possibilities. Gamification proposals for the classroom must be constantly monitored, since their development and use does not ensure success in teaching. We study the impact of gamification in the teaching of mathematics, analyzing its role in the treatment of geometric cone and cylinder figures with 13 and 14 years old students. From a descriptive quantitative approach of quasi-experimental type, with a control and pilot group and test application, a classical and implicative statistical analysis is carried out, showing a higher percentage of correct answers from the pilot group, in the item on the relationship between the volume of the cone and the cylinder, with 96.3%, in contrast to 73.08% obtained by the control group. In addition, a behavior with a high level of similarity (84.4%) is shown between the use of virtual games and satisfactorily answering the items. This suggests that this educational medium can cause improvements in the learning of students who seem to be prone to its use.


2021 ◽  
Vol 12 (e) ◽  
pp. e85-e85
Author(s):  
G Rai Subodha Kumar ◽  
Nagesha Parvathi ◽  
RangeGowda Suresh ◽  
Rangaswamy Umadevi ◽  
Nirvanappa Vinay

Background: The incidence of Hepatitis C virus (HCV) infection among patients with Lichen planus (LP) varies considerably. There is also lack of data in Indian population. Due to these variation, this study is to assessing the prevalence of HCV infection among patients with CLP in Hassan Karnataka. Methods: 135 clinically diagnosed cases of Lichen planus more than 18 years of age will be included as cases.147 patients having skin diseases other than lichen planus will be included as controls. Details of the patients personal history and family history,medical history and blood transfusion history will be collected. Detection of antibodies against HCV (anti-HCV) by enzyme-linked immunosorbent assay (ELISA). Results: Anti-HCV antibodies were found in 3(2.2%) patients of the case group and 1(0.7%) in control group. P value is 0.274, not statistically significant. Conclusion: Currently, there is no evidence confirming the relationship between HCV infection and CLP in Hassan Karnataka. However, there is a need for further research on larger groups of


2021 ◽  
Author(s):  
Taiyong Bi ◽  
Hui Kou ◽  
Xue Li ◽  
Yuxia He ◽  
Siqi Chen ◽  
...  

Abstract The improvements of attention by mindfulness training had been proved. But the effects of mindfulness training on attention to emotional stimuli were mixed. We employed a randomized, controlled design to investigate the effects of mindfulness training on the attention to emotional expressions, and investigated whether baseline levels of dispositional mindfulness and emotional intelligence would moderate the intervention effects. Forty participants received 8-week mindfulness training and another forty participants attended two lectures about mindfulness. All participants completed the visual search task, the Five Facet Mindfulness Questionnaire, and the Emotional Intelligence Scale at both pre-training and post-training. The improvements of search efficiencies were larger in the mindfulness group than those in the control group for sad and angry faces, but not for happy faces (F(2, 156)=4.04, p=0.019, η2=0.05). In addition, baseline emotional intelligence (βsadness=-4.49, t=-2.08, p=0.041, 95%CI [-8.78, -0.19]; βanger=-7.39, t=-4.08, p<0.001, 95%CI [-10.99, -3.78]) but not dispositional mindfulness (βsadness=3.17, t=1.56, p=0.124, 95%CI [-0.89, 7.22]; βanger=-1.89, t=-1.02, p=0.313, 95%CI [-5.61, 1.82]) played a significantly moderating role in the relationship between mindfulness training and emotional attention to sadness and anger. The search efficiencies of negative emotions (i.e., anger and sadness) but not positive emotions (i.e., happiness) were significantly improved by mindfulness training. Individuals with high level of baseline emotional intelligence showed significant improvement on the search efficiencies relative to those with low level of emotional intelligence.


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