The Correlation of Fc-gamma Receptor I (CD64) Expression and Procalcitonin in Early Onset Neonatal Sepsis

2017 ◽  
Vol 9 (6) ◽  
Author(s):  
Zenia Angelina ◽  
Eko Sulistijono ◽  
Loeki Enggar Fitri
Keyword(s):  
Risk Factors ◽  
Neonatal Sepsis ◽  
Early Onset ◽  
Pearson Correlation ◽  
Chi Square ◽  
Cd64 Expression ◽  
Gamma Receptor ◽  
Chi Square Test ◽  
Kolmogorov Smirnov ◽  
Neonatal Risk Factors

Objective: The aim of this study is to prove the relationship of FcγRI (CD64) expression and Procalcitonin value in earlyonset neonatal sepsis to assist in diagnosis of early-onset neonatal sepsis. Method: A descriptive and analytical case control study was conducted in dr. Saiful Anwar General Hospital Malang. There were 40 children divided into two groups: 1). Group of infants with neonatal risk factors who express signs of SIRS and proven by blood culture; 2). Group of infants with neonatal risk factors who showed no sign for SIRS. Both groups were performed examination of FcγRI (CD64) expression with flowcytometry and Procalcitonin value with ELISA. Data were statistically analyzed using normality test (Kolmogorov-Smirnov), chi square test, t test and Pearson correlation. We used SPSS 16 for this analysis. Results: The study showed that the FcγRI (CD64) expression and Procalcitonin value were higher in the infants group with proven early-onset neonatal sepsis (p less than 0.05). There was a significant relationship between FcγRI (CD64) expression and the Procalcitonin value (p=0.036). Conclusions: We conclude that expression of FcγRI (CD64) and Procalcitonin value were higher in the infants group with proven early-onset neonatal sepsis. There is a positive relationship between FcγRI (CD64) expression and Procalcitonin value in early onset neonatal sepsis

ASSESSING RISK FACTORS OF MALARIA IN LAKHIMPUR DISTRICT OF ASSAM

2021 ◽  
pp. 15-17
Author(s):  
Naba Jyoti Saikia ◽  
Anoop Dev
Keyword(s):  
Risk Factors ◽  
Climatic Factors ◽  
Malaria Incidence ◽  
Pearson Correlation ◽  
Age Groups ◽  
Host Factors ◽  
Primary Role ◽  
Age Group ◽  
Chi Square ◽  
Chi Square Test

Malaria is a life-threatening parasitic disease transmitted from person to person through the bite of a female Anopheles mosquito. The transmission of malaria can be determined by climatic and host factors. The objective of this paper is to trace the host factors of malaria incidence and also to determine the relationship between climatic factors and malaria incidence in Lakhimpur district of Assam. In order to examine the association between monthly malaria incidence rates and climatic variables, Pearson correlation analysis has been used. Also, Chi-square test for independence of attributes is performed to trace the host factors of malaria incidence. A uctuating trend was observed for reported malaria cases during the years 2000-2011. Both positive and negative correlation have occurred between climatic variable and MIR. Also, we have observed that male is more affected by malaria incidence than female. Among the age groups, the age group 15-39 years was found most affected age group than other age groups. After Chi-square test for independence of attributes we reveal that malaria depends on sex and age. SUMMARY: From our study, we suggest that even if the climatic factors play a primary role for transmission of malaria, sex and age are other important risk factors in characterizing malaria incidence in the district.

scholarly journals Determinants of low APGAR score among preeclamptic deliveries in Cipto Mangunkusumo Hospital: a retrospective cohort study in 2014

2015 ◽  
Vol 24 (3) ◽  
pp. 183-9 ◽  
Author(s):  
Sulaeman A. Susilo ◽  
Karina N. Pratiwi ◽  
Adly N.A. Fattah ◽  
Rima Irwinda ◽  
Noroyono Wibowo
Keyword(s):  
Risk Factors ◽  
Apgar Score ◽  
Early Onset ◽  
Hellp Syndrome ◽  
Retrospective Cohort ◽  
Significant Risk ◽  
Chi Square ◽  
Chi Square Test ◽  
Physiologic Maturity ◽  
Early Onset Preeclampsia

Background: Preeclampsia has great implication on adverse neonatal outcome. Appearance, pulse, grimace, activity, respiration (APGAR) score at 1 or 5 minutes is one of the indicators of physiologic maturity of the infant. Therefore, the aim of this study was to know the correlation of APGAR score in preeclamptic deliveries with its risk factors. Methods: This study was a retrospective cohort. Data were collected from January to December 2013 including all preeclamptic women with singleton live pregnancies who delivered their babies in Cipto Mangunkusumo Hospital, Jakarta. The primary outcome was APGAR score. There were some determinants conducted in this study. Binary logistic was used as multivariate analysis to analyze the correlation between APGAR score and risk factors of preeclampsia, data were analyzed using chi square test. Results: Out of 450 preeclamptic women, 446 of them met the inclusion criteria. Low APGAR scores at 1 and 5 minutes were found in 19% (86/446) and 5.4% (24/446) of neonates respectively. Early onset of preeclampsia (adjusted OR = 4.577; 95% CI = 2.147 - 9.757), white blood cell ≥ 15,000/μL (adjusted OR = 3.315; 95% CI = 1.738 – 6.324), HELLP syndrome (adjusted OR = 2.00; 95% CI = 1.38 – 2.91) were independent risk factors for having infant with low APGAR score at 1 minute. Meanwhile, there was no significant risk factors at 5 minutes APGAR score after adjustment.Conclusion: Leukocytosis, early onset preeclampsia, preterm birth, and thrombocytopenia, severity of preeclampsia, and HELLP syndrome are independent risks of having infant born with low APGAR score at 1 minute in preeclamptic deliveries.

scholarly journals Qualitative C-reactive protein as a marker of neonatal sepsis in a tertiary neonatal unit in Sudan

2013 ◽  
Vol 1 (2) ◽  
pp. 21
Author(s):  
Abdelmoneim E. Kheir ◽  
Ghada A. Jobara ◽  
Kamal M. Elhag ◽  
Mohamed Z. Karar
Keyword(s):  
Risk Factors ◽  
Blood Culture ◽  
Neonatal Sepsis ◽  
Neonatal Intensive Care ◽  
University Hospital ◽  
C Reactive Protein ◽  
Chi Square ◽  
Reactive Protein ◽  
Chi Square Test ◽  
A Prospective Study

Sepsis is one of the most common causes of morbidity and mortality in newborns. Diagnosis of neonatal sepsis may be difficult because clinical presentations are often non-specific. The aim of this study was to evaluate the role of qualitative C-reactive protein in the diagnosis of neonatal sepsis, and examine the correlation between C-reactive protein, blood culture and risk factors for sepsis. This was a prospective study, conducted in the Neonatal Intensive Care Unit at Soba University Hospital, Sudan. A total of seventy babies with a clinical diagnosis of sepsis were included. Chi square test was used to determine the association between C-reactive protein and risk factors for sepsis and also the association between C-reactive protein and blood culture. Blood culture was positive in 41.4% of babies, and C-reactive protein was positive in 58% of babies with positive blood culture. There was significant association between C-reactive protein results and blood culture (P=0.00). In conclusion, we can assume that Creactive protein is a reliable diagnostic marker of neonatal sepsis, especially in developing communities with poor resources.

scholarly journals Relationship between enuresis and obstructive sleep apnea–hypopnea syndrome in children

2020 ◽  
Vol 48 (12) ◽  
pp. 030006052097740
Author(s):  
Chen Sun ◽  
Yingpeng Xu ◽  
Chenxi Luo ◽  
Qi Li
Keyword(s):  
Risk Factors ◽  
Obstructive Sleep Apnea ◽  
Logistic Regression ◽  
Sleep Apnea ◽  
Pearson Correlation ◽  
Apnea Hypopnea Index ◽  
Chi Square ◽  
Obstructive Sleep ◽  
Chi Square Test ◽  
Hypopnea Syndrome

Objective We explored the relationship between enuresis and obstructive sleep apnea–hypopnea syndrome (OSAHS) in children and influencing factors of enuresis with OSAHS. Methods We recruited 196 children ≥5 years old from the otolaryngology outpatient department, who experienced snoring and underwent nasopharynx lateral radiography and in-laboratory polysomnography. We analyzed correlations between the apnea–hypopnea index (AHI) and lowest oxygen saturation (L-SaO2) with age, body mass index (BMI), tonsil size, and adenoidal–nasopharyngeal (A/N) ratio using the Pearson correlation test. Differences in severe OSAHS prevalence, age, AHI, L-SaO2, tonsil size, and A/N ratio between children with and without enuresis were assessed using the chi-square test and t-test. Risk factors of enuresis were analyzed using logistic regression. Follow-up was conducted to assess remission in children with enuresis after adenotonsillectomy. Results BMI, tonsil size, and A/N ratio were correlated with AHI and L-SaO2. Severe OSAHS prevalence, AHI, tonsil size, and A/N ratio were higher and L-SaO2 were lower in children with enuresis. Logistic regression showed that BMI, AHI, tonsil size, and sleep apnea were risk factors for enuresis. Conclusions Our study findings showed that enuresis was associated with OSAHS in children. Adenotonsillectomy may improve the symptoms of enuresis.

scholarly journals Association of Maternal and Neonatal Risk Factors with Early Onset Neonatal Sepsis

2021 ◽  
Vol 4 (3) ◽  
pp. 78-83
Author(s):  
 Debabrata Roy ◽  
M.A Mannan ◽  
A.S.M Selim ◽  
Debashish Saha ◽  
Sarbari Saha ◽  
...  
Keyword(s):  
Risk Factors ◽  
Neonatal Sepsis ◽  
Early Onset ◽  
Neonatal Risk Factors

scholarly journals Investigating The Risk Factors for Hypertension in A Population-Based Study: Fasa PERSIAN COHORT Data

2020 ◽  
Author(s):  
Mostafa Bijani ◽  
Saeed Parvizi ◽  
Azizallah Dehghan ◽  
Massih Sedigh Rahimabadi ◽  
Mahsa Rostami Chijan ◽  
...  
Keyword(s):  
Risk Factors ◽  
Pearson Correlation ◽  
Population Based ◽  
Cross Sectional Study ◽  
P Value ◽  
Chi Square ◽  
Cross Sectional ◽  
Test Analysis ◽  
Chi Square Test ◽  
Study Population

Abstract Background: High prevalence of hypertension (HTN) and its subsequent serious complications make this disease as a major health-treatment concern in many societies. The current study aimed to investigate known factors as risk factors for hypertension and the way of their association in study population of Fasa cohort in south of Iran at 2019.Methods: This is an analytical-cross sectional study. Study population was the individuals covered by Fasa cohort. Information of the first phase of Fasa Persian cohort in south of Iran was used in the study. Independent t-test, chi-square test, analysis of variances, Pearson correlation coefficient, and logistic regression were used to analyze data. Data was analyzed using SPSS software version 22, and P-value<0.05 was considered statistically significant.Results: Out of the population of 10111 individuals of the study, 5546(54.86%) subjects were female and 4565(45.16%) were male. The overall prevalence of hypertension was 41.8 %. In the present study (28/5%) were with HTN stage 1, and (13/3%), were with HTN stage 2. In addition, a significant association was observed among HTN and cardiovascular diseases, diabetes and renal failure (p<0.5).Conclusions: prevalence of HTN in study population is considerable. Given its hazardous complications, application of appropriate methods in order to screen, prevent and treat HTN is necessary. In addition, using training programs, changing lifestyle, and promoting self-care behaviors can be effective in prevention, control, and decrease in hazardous complications caused by HTN.

scholarly journals Risk factors of complications subsequent third molar extractions: A prospective cohort study

2021 ◽  
Vol 24 (4) ◽  
Author(s):  
Dena Ali
Keyword(s):  
Risk Factors ◽  
Pearson Correlation ◽  
Maxillofacial Surgery ◽  
Third Molar ◽  
Oral And Maxillofacial Surgery ◽  
Surgical Removal ◽  
Chi Square ◽  
Surgical Extraction ◽  
Alveolar Osteitis ◽  
Chi Square Test

Objective: The aim of this study was to determine the complications that were associated with the surgical removal of third molars (M3s), and to assess the association of patient, anatomic, and surgical risk factors with the postoperative complications of surgically removed impacted M3s. Material and Methods: This study was a cohort prospective study conducted on patients, aged 17 and older, admitted to the oral and maxillofacial surgery clinic. All patients who needed 1 or more extractions were included and totalled 268 patients with 314 extracted teeth. Risk factors were divided into patient factors, anatomic factors and surgical factors. The postoperative complication variables mainly included: pain, alveolar osteitis, infection, bleeding, swelling, trismus. Statistical analysis used: Chi-square test was used for the bivariate analyses while Pearson correlation coefficient (1- tailed) test was used for the purpose of determining the association between the study variables. The significance of associations was considered statistically significant at P < 0.05. Results: Patients aged of 25 years and above experienced more complications, 39 (88.6%). With respect to gender, females experienced more complications, 29 (65.9%). Mandibular M3s had more complications than maxillary M3s, 34 (8.0%), followed by distoangular inclined M3s, 23 (52.3%), and last was full bony impaction, 13 (29.5%). Pain was the most frequent complication, 18 (40.9%), followed by alveolar osteitis 12 (27.3%). Conclusion: The results indicated that the most frequently complications were pain, infection, alveolar osteitis. These complications were associated with common risk factors such as age, gender, medical history, M3 angulation, impaction level, bone removal, tooth sectioning, and number of M3 removed per session. Keywords  Complications; Surgical extraction; Third molar.

NEONATAL SEPSIS AND IDENTIFICATION OF RISK FACTORS: STUDY IN AVBRH HOSPITAL SAWANGI

2019 ◽  
Vol 3 (6) ◽  
Author(s):  
Pramod P. Singhavi
Keyword(s):  
Risk Factors ◽  
Neonatal Sepsis ◽  
Early Onset ◽  
Late Onset ◽  
Signs And Symptoms ◽  
Premature Rupture ◽  
Maternal Risk ◽  
Late Onset Sepsis ◽  
Early Onset Sepsis ◽  
Meconium Stained Amniotic Fluid

Introduction: India has the highest incidence of clinical sepsis i.e.17,000/ 1,00,000 live births. In Neonatal sepsis septicaemia, pneumonia, meningitis, osteomyelitis, arthritis and urinary tract infections can be included. Mortality in the neonatal period each year account for 41% (3.6 million) of all deaths in children under 5 years and most of these deaths occur in low income countries and about one million of these deaths are due to infectious causes including neonatal sepsis, meningitis, and pneumonia. In early onset neonatal sepsis (EOS) Clinical features are non-specific and are inefficient for identifying neonates with early-onset sepsis. Culture results take up to 48 hours and may give false-positive or low-yield results because of the antenatal antibiotic exposure. Reviews of risk factors has been used globally to guide the development of management guidelines for neonatal sepsis, and it is similarly recommended that such evidence be used to inform guideline development for management of neonatal sepsis. Material and Methods: This study was carried out using institution based cross section study . The total number neonates admitted in the hospital in given study period was 644, of which 234 were diagnosed for neonatal sepsis by the treating pediatrician based on the signs and symptoms during admission. The data was collected: Sociodemographic characteristics; maternal information; and neonatal information for neonatal sepsis like neonatal age on admission, sex, gestational age, birth weight, crying immediately at birth, and resuscitation at birth. Results: Out of 644 neonates admitted 234 (36.34%) were diagnosed for neonatal sepsis by the paediatrician based on the signs and symptoms during admission. Of the 234 neonates, 189 (80.77%) infants were in the age range of 0 to 7 days (Early onset sepsis) while 45 (19.23%) were aged between 8 and 28 days (Late onset sepsis). Male to female ratio in our study was 53.8% and 46% respectively. Out of total 126 male neonates 91(72.2%) were having early onset sepsis while 35 (27.8%) were late onset type. Out of total 108 female neonates 89(82.4%) were having early onset sepsis while 19 (17.6%) were late onset type. Maternal risk factors were identified in 103(57.2%) of early onset sepsis cases while in late onset sepsis cases were 11(20.4%). Foul smelling liquor in early onset sepsis and in late onset sepsis was 10(5.56%) and 2 (3.70%) respectively. In early onset sepsis cases maternal UTI, Meconium stained amniotic fluid, Multipara and Premature rupture of membrane was seen in 21(11.67%), 19 (10.56%), 20(11.11%) and 33 (18.33%) cases respectively. In late onset sepsis cases maternal UTI, Meconium stained amniotic fluid, Multipara and Premature rupture of membrane was seen in 2 (3.70%), 1(1.85%), 3 (5.56%) and 3 (5.56%) cases respectively. Conclusion: Maternal risk identification may help in the early identification and empirical antibiotic treatment in neonatal sepsis and thus mortality and morbidity can be reduced.

scholarly journals Prevalence and risk factors of apical periodontitis in endodontically treated teeth in a selected population of Brazilian adults

2008 ◽  
Vol 19 (1) ◽  
pp. 34-39 ◽  
Author(s):  
Carlos Estrela ◽  
Cláudio Rodrigues Leles ◽  
Augusto César Braz Hollanda ◽  
Marcelo Sampaio Moura ◽  
Jesus Djalma Pécora
Keyword(s):  
Risk Factors ◽  
Confidence Intervals ◽  
Odds Ratio ◽  
Apical Periodontitis ◽  
Endodontic Treatment ◽  
Technical Quality ◽  
Endodontically Treated Teeth ◽  
Chi Square ◽  
Chi Square Test

The aim of this study was to assess the prevalence and risk factors of apical periodontitis in endodontically treated teeth in a selected population of Brazilian adults. A total of 1,372 periapical radiographs of endodontically treated teeth were analyzed based on the quality of root filling, status of coronal restoration and presence of posts associated with apical periodontitis (AP). Data were analyzed statistically using odds ratio, confidence intervals and chi-square test. The prevalence of AP with adequate endodontic treatment was low (16.5%). This percentage dropped to 12.1% in cases with adequate root filling and adequate coronal restoration. Teeth with adequate endodontic treatment and poor coronal restoration had an AP prevalence of 27.9%. AP increased to 71.7% in teeth with poor endodontic treatment associated with poor coronal restoration. When poor endodontic treatment was combined with adequate coronal restoration, AP prevalence was 61.8%. The prevalence of AP was low when associated with high technical quality of root canal treatment. Poor coronal restoration increased the risk of AP even when endodontic treatment was adequate (OR=2.80; 95%CI=1.87-4.22). The presence of intracanal posts had no influence on AP prevalence.

scholarly journals Bacteriological Safety of Blood Collected for Transfusion at University of Gondar Hospital Blood Bank, Northwest Ethiopia

2013 ◽  
Vol 2013 ◽  
pp. 1-7 ◽  
Author(s):  
Hailegebriel Wondimu ◽  
Zelalem Addis ◽  
Feleke Moges ◽  
Yitayal Shiferaw
Keyword(s):  
Risk Factors ◽  
Bacterial Contamination ◽  
Standard Procedure ◽  
Cross Sectional Study ◽  
Northwest Ethiopia ◽  
Blood Bank ◽  
Bacterial Isolation ◽  
Chi Square ◽  
Cross Sectional ◽  
Chi Square Test

Background. Transfusion associated bacterial infection has remained more frequent with a sever risk of morbidity and mortality. This study assessed the bacteriological safety of blood collected for transfusion. Method. A cross-sectional study was conducted at University of Gondar hospital blood bank from December 2011 to June 2012. Bacterial isolation, identification, and antimicrobial susceptibility tests were done as per the standard procedure. Chi-square test and P value were used to assess associations between risk factors and the bacterial isolation rate. Results. Twenty-one (15.33%) blood units were found contaminated with bacteria, and 95.24% contamination was due to external sources. The commonly isolated bacteria were Staphylococcus aureus, Coagulase negative Staphylococci, Escherichia coli, Klebsiella species, Streptococci species, Enterobacter species, and Citrobacter species. All of the bacteria isolated were 100% sensitive to Gentamicin, Chloramphenicol, Amoxicillin, and Doxycycline. Multiple antimicrobial resistances were observed in 66.7% of the isolates. Not using glove by phlebotomist, touching disinfected phlebotomy site and double puncture at the same hand or both hands of a donor were found to be risk factors for bacterial contamination. Conclusion. Bacterial contamination of blood to be transfused is a common problem in the hospital. So attention should be given to activities performed at the blood bank for safe transfusion practices.

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