scholarly journals Determinants of low APGAR score among preeclamptic deliveries in Cipto Mangunkusumo Hospital: a retrospective cohort study in 2014

2015 ◽  
Vol 24 (3) ◽  
pp. 183-9 ◽  
Author(s):  
Sulaeman A. Susilo ◽  
Karina N. Pratiwi ◽  
Adly N.A. Fattah ◽  
Rima Irwinda ◽  
Noroyono Wibowo

Background: Preeclampsia has great implication on adverse neonatal outcome. Appearance, pulse, grimace, activity, respiration (APGAR) score at 1 or 5 minutes is one of the indicators of physiologic maturity of the infant. Therefore, the aim of this study was to know the correlation of APGAR score in preeclamptic deliveries with its risk factors. Methods: This study was a retrospective cohort. Data were collected from January to December 2013 including all preeclamptic women with singleton live pregnancies who delivered their babies in Cipto Mangunkusumo Hospital, Jakarta. The primary outcome was APGAR score. There were some determinants conducted in this study. Binary logistic was used as multivariate analysis to analyze the correlation between APGAR score and risk factors of preeclampsia, data were analyzed using chi square test. Results: Out of 450 preeclamptic women, 446 of them met the inclusion criteria. Low APGAR scores at 1 and 5 minutes were found in 19% (86/446) and 5.4% (24/446) of neonates respectively. Early onset of preeclampsia (adjusted OR = 4.577; 95% CI = 2.147 - 9.757), white blood cell ≥ 15,000/μL (adjusted OR = 3.315; 95% CI = 1.738 – 6.324), HELLP syndrome (adjusted OR = 2.00; 95% CI = 1.38 – 2.91) were independent risk factors for having infant with low APGAR score at 1 minute. Meanwhile, there was no significant risk factors at 5 minutes APGAR score after adjustment.Conclusion: Leukocytosis, early onset preeclampsia, preterm birth, and thrombocytopenia, severity of preeclampsia, and HELLP syndrome are independent risks of having infant born with low APGAR score at 1 minute in preeclamptic deliveries.

Author(s):  
Poornima Shankar ◽  
Kavitha Karthikeyan ◽  
Amrita Priscilla Nalini ◽  
Sindhura M. ◽  
Gowtham Kim

Background: Preeclampsia is being increasingly recognized as two different entities: early-onset preeclampsia occurring at less than 34 weeks of gestation, and late-onset disease occurring at 34 or more weeks of gestation. Early-onset and late-onset pre-eclampsia are found to have different implications for the mother and neonate. The aim of this study is to compare the risk factors, maternal and fetal outcomes in early (<34 weeks) versus late (≥34weeks) onset preeclampsia.Methods: 208 patients diagnosed with pre-eclampsia in Chettinad Academy of Research and Education over a period of three years (From January 2014 to December 2016) were retrospectively studied. Patients were classified as early onset and late onset pre-eclampsia based on the gestational age of onset. Data on risk factors, maternal and fetal outcomes were collected and analyzed using Chi Square and Fisher’s test and compared.Results: The overall preeclampsia rate was 6.3%. Early onset and late onset were 34.6% and 65.3% respectively and the rate increased with increasing gestational age.35.3% of patients with late onset preeclampsia and 55.6% patients of early onset type required more than one drug which is a statistically significant difference. Proteinuria more than 3gm/l/day was significantly more in late onset preeclampsia than in early onset preeclampsia. 55.5% of patients with early onset pre-eclampsia required MgSO4 when compared to 17.4%. There was no statistically significant difference in the rate of caesarean section (61.1% vs 73.5%). Altered coagulation profile was significantly more in early onset preeclampsia (11.1%). The incidence of oligohydramnios, SGA and low APGAR at 5 minutes of birth were significantly high in early onset pre-eclampsia when compared to late onset type.Conclusions: Patients with early onset pre-eclampsia are found to have significantly higher rates of specific maternal and fetal morbidity when compared to the late onset type.


2013 ◽  
Vol 131 (1) ◽  
pp. 27-34 ◽  
Author(s):  
Orlando Milhomem Mota ◽  
Maria Paula Curado ◽  
José Carlos Oliveira ◽  
Edesio Martins ◽  
Daniela Medeiros Milhomem Cardoso

CONTEXT AND OBJECTIVESEsophageal cancer is the eighth commonest type of cancer worldwide, occupying sixth place in terms of mortality. Smoking and alcohol use are known risk factors for this type of cancer. The aim here was to evaluate the risk factors for esophageal cancer in a low-incidence area.DESIGN AND SETTINGCase-control study in Goiânia, with 99 cases of esophageal cancer and 223 controls.METHODSThe variables were sociodemographic, dietary, occupational and lifestyle data. The sample was analyzed using the chi-square test, Mann-Whitney test and Mantel-Haenszel approach for multivariate analysis. Odds ratios (OR) were calculated with 5% significance and 95% confidence intervals.RESULTSThe risk of esophageal cancer was higher in patients ≥ 55 years (OR = 1.95; P < 0.001). Patients from rural areas were at greater risk of esophageal cancer (OR = 4.9; P < 0.001). Smoking was a risk factor among the cases (OR = 3.8; P < 0.001), as was exposure to woodstoves (OR = 4.42; P < 0.001). The practice of oral sex was not a risk factor (OR = 0.45; P = 0.04). Consumption of apples, pears, vegetables, cruciferous vegetables and fruit juices were protective against esophageal cancer.CONCLUSIONIn a region in which the incidence of esophageal cancer is low, the most significant risk factors were exposure to woodstoves, smoking and living in rural areas.


2015 ◽  
Vol 36 (6) ◽  
pp. 3757 ◽  
Author(s):  
Soraia Figueiredo de Souza ◽  
Luciana Dos Santos Medeiros ◽  
Adriane De Souza Belfort ◽  
Andrey Luiz Lopes Cordeiro ◽  
Michelle Federle ◽  
...  

Blood samples were collected from 89 cats to assess the prevalence of IgG antibodies against Toxoplasma gondii by indirect immunofluorescence (IIF) and the possible risk factors associated with feline Toxoplasma gondii infection. An epidemiological questionnaire was developed and implemented for owners of domestic cats domiciled in Rio Branco, Acre. The results were statistically evaluated with the odds ratio and chi-square tests, considering the significance level of 5%. Of 89 animals’ samples, 22 had antibodies against Toxoplasma gondii. Among the 22 reactive animals, 15 (68.19%) were female, 15 (68.19%) were less than one year old and 20 (90%) were cross breed. Concerning risk factors, there was no difference (p > 0.05) between the variables evaluated by the chi-square test. Moreover, 16 (72%) cats were fed a mixed diet, 20 (90%) of the cats had hunting habits, 18 (81%) had contact with animals of another species, 11 (50%) had access to the street, and 22 (95%) lived in homes that had areas of grass or dirt. In conclusion, the prevalence of anti-Toxoplasma gondii in domestic cats was 22.7%, and there were no significant risk factors for feline toxoplasmosis in the municipality of Rio Branco, Acre.


2016 ◽  
Vol 29 (1) ◽  
pp. 9-14
Author(s):  
Omole Ohonsi Abiodun ◽  
Belga Francis

Objective (s): To determine the aetiological factors of preterm deliveries at Aminu Kano Teaching Hospital, Kano, Nigeria..Materials and methods: This case-control study was conducted between 1st June 2006 and 31st May 2007.One hundred and forty eight women with preterm deliveries (cases) were compared with seven hundred and forty women who delivered at term (control). Data analysis was done using Epi- Info software (6.0 CDC Atlanta Georgia, USA). Univariate and multivariate logistic regression analysis were performed and the results were expressed as odds ratio (OR) with 95% confidence interval (CI). The contribution of the risk factors were estimated using chi square test and a p-value of < 0.05 was taken as significant.Results: The period incidence of preterm deliveries was 69 per 1000 births. Unbooked and low socioeconomic statuses, primigravidity, previous preterm deliveries, multiple pregnancies, pre-eclampsia, and malaria in pregnancy were significant risk factors that were associated with preterm delivery. These associations were still demonstrable after adjusting for confounding variables.Conclusion: Early girl marriage and childbearing and spontaneous pre-labour rupture of membranes not to be independent risk factors in this study. Women with risk factors should be managed in specialist hospitals.Bangladesh J Obstet Gynaecol, 2014; Vol. 29(1) : 9-14


2016 ◽  
Vol 3 (3) ◽  
pp. 188
Author(s):  
Nurul Hikmah Petrana ◽  
Ova Emilia ◽  
Heru Pradjatmo

Background: Urinary retention after vaginal delivery is a common problem with incidence 1.7% - 17.9%. Assissted vaginal delivery is one risk factor for the occurence of urinary retention.Objective: to compare urinary retention between normal vaginal delivery and assissted vaginal delivery using extraction vacum, and evaluate factors related to urinary retention.Method: The study was prospective cohort design, conducted in 3 hospitals and 2 primary health centres during 6 month period since September 2013- February 2014. Subjects were divided into two groups i.e. normal delivery and assissted delivery using extraction vacum, each 118 subjects. Events of urinary retention was assessed and also related factors were identified. Analysis used Chi-Square test, Fisher test and also logistic regression analysis.Result and Discussion: In total 236 subjects were involved, there was no difference in age and parity among the subjects. Incidence of urinary retention among extraction vacum delivery group was higher (32.2%) compare to normal delivery (11.9%). Multivariate analysis using logistic regression showed that extraction vacum (p=0.074; OR 2.71; 95% CI 1.55-4.73), baby weight (p= 0.230; OR 1.95; 95% CI 0.655.84) and perineal injury (p= 0.614; OR 1.35; 95% CI 0.41-4.36) were not significant risk factors for urinary retention. Length of labour (p=0.003; OR 3.71; 95% CI 1.55-8.86) and parity (p= 0.023; OR 2.29; 95% CI 1.2-4.66) were significant risk factors for urinary retention.Conclusion: Urinary retention is higher among vaginal delivery with extraction vacum compare to normal delivery. Length of labour and parity are external factors related to urinary retention. Keywords: Assissted vaginal delivery, extraction vacum, normal delivery, urinary retention, postpartum


Author(s):  
Zenia Angelina ◽  
Eko Sulistijono ◽  
Loeki Enggar Fitri

Objective: The aim of this study is to prove the relationship of FcγRI (CD64) expression and Procalcitonin value in earlyonset neonatal sepsis to assist in diagnosis of early-onset neonatal sepsis. Method: A descriptive and analytical case control study was conducted in dr. Saiful Anwar General Hospital Malang. There were 40 children divided into two groups: 1). Group of infants with neonatal risk factors who express signs of SIRS and proven by blood culture; 2). Group of infants with neonatal risk factors who showed no sign for SIRS. Both groups were performed examination of FcγRI (CD64) expression with flowcytometry and Procalcitonin value with ELISA. Data were statistically analyzed using normality test (Kolmogorov-Smirnov), chi square test, t test and Pearson correlation. We used SPSS 16 for this analysis. Results: The study showed that the FcγRI (CD64) expression and Procalcitonin value were higher in the infants group with proven early-onset neonatal sepsis (p less than 0.05). There was a significant relationship between FcγRI (CD64) expression and the Procalcitonin value (p=0.036). Conclusions: We conclude that expression of FcγRI (CD64) and Procalcitonin value were higher in the infants group with proven early-onset neonatal sepsis. There is a positive relationship between FcγRI (CD64) expression and Procalcitonin value in early onset neonatal sepsis


2021 ◽  
Vol 21 (1) ◽  
pp. 1-6
Author(s):  
Asti Widuri

Abstract: Cerumen was glandular secretions at the outer one-third of the ear mixed with exfoliated squamous epithelium. The jaw's movement keeps the cerumen in the ear canal in a state of balance, so it is clean, protects and lubricates the external auditory canal. Impacted cerumen is also caused by excessive production, narrow canal anatomy, viscosity wax, and irritation due to cotton-tipped swabs habits. This study aims to determine whether chewing habits influence the degree of cerumen obstruction in patients with impacted cerumen. The study was a cross-sectional method in impacted cerumen patients at 17-80 years old in the ENT clinic of District Hospital Wates, Kulon Progo, Yogyakarta, Indonesia. Risk factors assessed were education, age, gender, chewing habits, and cotton-tipped swabs habits. The data were then analyzed by chi-square test. Of 80 respondents with the dominant age range 17-38 years (58.8 %), the number of males was 47 (58.8 %), and females were 33 (41.2 %). The significant risk factors comprised the chewing habit and the use of cotton-tipped swabs. Factors affecting the degree of cerumen in patients with impacted cerumen were the chewing habits and cotton-tipped swabs habits.


2014 ◽  
Vol 128 (2) ◽  
pp. 159-162 ◽  
Author(s):  
N Sethi ◽  
P H Tay ◽  
A Scally ◽  
S Sood

AbstractIntroduction:Post-operative facial palsy is the most important potential complication of parotid surgery for benign lesions. The published prevalence of facial weakness is up to 57 per cent for temporary weakness and up to 7 per cent for permanent weakness. We aimed to identify potential risk factors for post-operative facial palsy.Materials and methods:One hundred and fifty patients who had undergone parotid surgery for benign disease were retrospectively reviewed. Tumour factors (size, location and histopathology), patient factors (age and sex) and operative factors (operation, surgeon grade, surgeon specialty and use of intra-operative facial nerve monitoring) were all analysed for significant associations with post-operative facial palsy.Results and analysis:The overall incidence of facial palsy was 26.7 per cent for temporary weakness and 2.6 per cent for permanent weakness. The associations between facial palsy and all the above factors were analysed using Pearson's chi-square test and found to be non-significant.Conclusion:These outcomes compare favourably with the literature. No significant risk factors were identified, suggesting that atraumatic, meticulous surgical technique is still the most important factor affecting post-operative facial palsy.


2015 ◽  
Vol 4 (3) ◽  
Author(s):  
Sagung Adi Sresti Mahayana ◽  
Eva Chundrayetti ◽  
Yulistini Yulistini

Abstrak  Berat Badan Lahir Rendah (BBLR) adalah bayi yang lahir dengan berat badan kurang dari 2500 g. BBLRmerupakan prediktor utama angka kesakitan dan kematian bayi. Tujuan penelitian ini adalah untuk menentukan faktorrisiko ibu, plasenta, janin dan lingkungan yang berpengaruh terhadap kejadian BBLR. Penelitian ini bersifat analitikdengan desain cross-sectional dengan mengumpulkan data retrospektif rekam medis ibu yang melahirkan bayi BBLRdi RSUP Dr. M. Djamil Padang dari Januari sampai Desember 2012. Pada 72 sampel yang didapatkan, faktor risikojanin dengan jenis kelamin laki-laki (61,1%) dan status sosioekonomi rendah (52,8%) memiliki proporsi yang lebihbesar pada kejadian BBLR. Analisis bivariat chi-square menunjukkan faktor risiko anemia (p=0,001) dan kelainanplasenta (p=0,049) memiliki hubungan statistik yang signifikan terhadap kejadian BBLR prematur dan dismatur.Pengaruh terbesar secara statistik terdapat pada faktor risiko anemia (p=0,001) dan paritas (p=0,022) pada analisismultivariat regresi logistik. Anemia, kelainan plasenta dan paritas merupakan faktor risiko yang berpengaruh terhadapkejadian BBLR prematur dan dismatur di RSUP Dr. M. Djamil Padang.Kata kunci: BBLR, prematur, dismatur, faktor risikoAbstract Low birthweight (LBW) is a birth weight under 2500 g. LBW is a major predictor of infant morbidity and mortality.The objective of this study was to determine maternal, placental, fetal and environmental risk factors that influencingLBW. This was a cross-sectional study by obtaining retrospective datas from medical records of mother who deliveredLBW babies at RSUP Dr. M. Djamil Padang from January until December 2012 period. Male fetal sex (61.1%) and lowsocioeconomic status (52.8%) were found in high rates on total 72 cases of LBW. Chi-square test showed anemia(p=0.001) and placental abnormalities (p=0.049) were statistically significant in LBW with premature and dysmature.Logistic regression test indicates anemia (p=0.001) and parity (p=0.022) are statistically influence LBW. Anemia,placental abnormalities and parity are significant risk factors resulting low birth weight babies with premature anddismature in RSUP Dr. M. Djamil Padang.Keywords:  LBW, premature, dysmature, risk factors


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