scholarly journals Are children safe from complications of leprosy? A study from North Kerala

2020 ◽  
Vol 2 ◽  
pp. 31-34
Author(s):  
Mekha Premachandran ◽  
Nikhil George ◽  
T. Binitha ◽  
Veena Nandakumar ◽  
Pulpadathil Jishna ◽  
...  
Keyword(s):  
Clinical Presentation ◽  
World Health ◽  
Tertiary Referral ◽  
Chi Square ◽  
Disease Manifestation ◽  
Tertiary Referral Center ◽  
Referral Center ◽  
Chi Square Test ◽  
Health Organization ◽  
Important Disease

Objectives: The aims of the study were (1) to document the demography and clinical profile of patients with leprosy at a tertiary referral center from 2009 to 2018. (2) To compare the disease manifestation in children aged 12 years/below and the same in patients above 12 years. Materials and Methods: Case records of all patients diagnosed to have leprosy as per the World Health Organization cardinal criteria at our tertiary referral center from 2009 to 2018 were included in this study. The findings recorded in those aged 12 years/below were compared with those above 12 years using Pearson’s Chi- square test. Results: A total of 705 patients who attended our institution during the 10 year period were diagnosed to have leprosy. Six hundred and sixty-four (94.2%) were above 12 years of age and 41 patients (5.8%) were aged 12 years or below. Lepromatous spectrum cases, pure neuritic cases, Grade 2 disability, and lepra reactions were not documented in any of the patients aged 12 years or below which were contrary to the observations in those above 12 years. The differences were found to be statistically significant. Limitations: Retrospective design and small number of childhood cases were the main limitations of the study. Conclusion: Clinical presentation of leprosy in children differs from that in adults. Detection of disease in childhood offers an opportunity to cure the disease with less risk of developing some of the important disease and therapy-related complications.

scholarly journals HUBUNGAN PENINGKATAN BERAT BADAN DAN KETIDAKTERATURAN SIKLUS HAID DENGAN PENGGUNA KB SUNTIK PADA AKSEPTOR KB DI PUSKESMAS PEMBINA PALEMBANG TAHUN 2018

2019 ◽  
Vol 8 (1) ◽  
Author(s):  
Bina Aquari Bina Aquari
Keyword(s):  
Significant Relationship ◽  
Hormonal Contraception ◽  
World Health ◽  
P Value ◽  
Chi Square ◽  
Cross Sectional ◽  
Chi Square Test ◽  
Monthly Period ◽  
Health Organization ◽  
The Relationship

ABSTRAK   Kontrasepsi Hormonal sebagai salah satu alat Kontrasepsi meningkat dan tajam. Menurut World Health Organization (WHO) 2014, Pengguna alat kontrasepsi suntik yaitu 35,3%, pil yaitu 30,5%, IUD yaitu 15,2%, Implant 7,3%, dan 11,7% Kontrasepsi lainnya. Tujuan penelitian ini untuk mengetahui apakah ada hubungan peningkatan berat badan dan ketidakteraturan siklus haid dengan KB suntik pada akseptor KB di Puskesmas Pembina Palembang Tahun 2018.Rumusan masalah penelitian ini adalah hubungan antara umur dan pengetahuan akseptor tentang KB Suntik di Puskesmas Pembina Palembang Tahun 2018.Penelitian ini menggunakan survey analitik dengan pendekatan cross sectional yang dilakukan dengan kuesioner.Uji Statistic yang dipakai adalah Uji Chi-Square. Populasi dalam penelitian ini berjumlah 62 orang dan seluruh Populasi dijadikan sampel. Dari hasil analisa univariat responden yang memakai KB Suntik lebih besar yaitu sebanyak 36 orang (58,1%), dan 26 orang (41,9%) yang tidak memakai KB Suntik. Responden yang berat badannya meningkat memakai kontrasepsi sebanyak 33 orang (53,2%), sedangkan responden yang berat badannya tidak meningkat sebanyak 29 orang (46,8%) dibandingkan dengan responden yang siklus haidnya tidak teratur adalah sebanyak 32 orang (51,6%). Hasil analisa statistik dengan menggunakan Uji Chi-Square dengan df = 1 ada hubungan yang bermakna peningkatan berat badan dengan KB Suntik pada akseptor KB diperoleh p value (0.006) lebih kecil dari (0,05) dan ada hubungan yang bermakna ketidakteraturan siklus haid dengan KB suntik pada akseptor KB diperoleh p value (0,011) lebih kecil dari (0,05). Saran agar petugas kesehatan meningkatkan kinerja dan sistem informasi mengenai masalah yang berhubungan dengan pemakaian KB Suntik.       ABSTRACT   The hormonal contraception as becoming on of the contraceptions tools which is increasing sharply. Based on world Health Organitation (WHO) the user of injected contraception is 35,3%, pill 30,5%, IUD 15%, implant 7,3%, and 11,7% for another contraception. The purpose of this research is for knowing wheter there is the increasing of weight and the irregular of monthly period with injected contraception for the acceptor at Puskesmas Pembina Palembang in 2014. The main case of this research is the relationship between the increasing of the weight and the irregular monthly period at Puskesmas Pembina Palembang in 2014. This research using analytic survey with cross sectional closing yhat was done by using questioner, the statistic test which take is Chi-Square test. The population in this reseacrh are 62 peoples, and all off them as becoming the sample from the result of respondent univariat analyze whom using the injected contraception in bigger that is exactly 36 people (58,1%) and 26 people (41,9%) whom do not using it. The respondent with their weight is increasing because of using contraception is 33 people (53,2%), while the respondent whom the weight do not increasing is 29 people (46,8%), when we compare with the respondent whom the monthly period is irregular are 32 people (51,6%). The result for statistic analyze by using the Chi-Square test with the df = 1 says that there is a significant relationship between the weight increasing with the injected contraception for the acceptor we get p value (0,006) is smaller than (0,05) and there is significant relationship between the injected contraception for the acceptor we get p value (0,011) with is smaller than (0,05). The sugestion of the health workes to increasing the performance the information sistem about the problem that is connected with the inject contraception using

scholarly journals Hubungan umur dan pekerjaan ibu menyusui dengan pemberian ASI eksklusif

2020 ◽  
Vol 9 (2) ◽  
pp. 153
Author(s):  
Rolita Efriani ◽  
Dhesi Ari Astuti
Keyword(s):  
Exclusive Breastfeeding ◽  
Maternal Age ◽  
World Health ◽  
P Value ◽  
Chi Square ◽  
Cross Sectional ◽  
Chi Square Test ◽  
Mother’S Age ◽  
Health Organization ◽  
Yogyakarta City

One of the efforts of the United Nations Children's Fund (UNICEF) and the World Health Organization (WHO) to reduce the Infant Morbidity and Mortality Rate (IMR) is to recommend that babies should only be breastfed for the first six months of life (exclusive breastfeeding). The coverage of exclusive breastfeeding in the Special Region of Yogyakarta was 73.3%. The lowest was in the city of Yogyakarta at 59.52%. This achievement had not yet reached the government's target of 80%. Puskesmas Umbulharjo 1 is the health center with the lowest exclusive breastfeeding coverage in Yogyakarta City at 39.15%. This study aims to determine the relationship between mothers' age and occupation with exclusive breastfeeding at Puskesmas Umbulharjo 1 Yogyakarta City. This research is an analytic survey with a cross-sectional approach. A sample of 64 mothers was taken from a population of 179 mothers who had babies aged 6-12 months. Data were analyzed by using the Chi-Square test. The results of the analysis of maternal age with exclusive breastfeeding obtained a p-value of 0.007 (p <0.05), while the analysis of maternal age with exclusive breastfeeding showed a p-value of 0.000 (p <0.05). In conclusion, there is a relationship between the mother's age and occupation and exclusive breastfeeding in the working area of Puskesmas Umbulharjo 1 Yogyakarta City

scholarly journals PENGARUH KEPATUHAN IBU HAMIL DALAM MENGKONSUMSI TABLET ZAT BESI DI WILAYAH KERJA PUSKESMAS MUARA DUA KOTA LHOKSEUMAWE

2019 ◽  
Vol 2 (1) ◽  
pp. 43
Author(s):  
Anita Marlina
Keyword(s):  
World Health Organization ◽  
Cross Sectional Study ◽  
World Health ◽  
Sectional Study ◽  
Chi Square ◽  
Cross Sectional ◽  
Purposive Sampling ◽  
Chi Square Test ◽  
Health Organization

<p>Berdasarkan data <em>World Health Organization</em> (WHO) 2005, kejadian anemiapada ibu hamil setiap tahunnya tahunnya mencapai lebih dari 500.000 orang. Laporan dari Dunia menyebutkan bahwa frekuensi anemia dalam kehamilan cukup tinggi, terutama di Negara-negara berkembang berkisar 10-22%. Menurut data dari Dinas Kesehatan Nanggroe Aceh Darussalam, jumlah ibu hamil di wilayah Kota Lhokseumawe sebesar 4.253 jiwa, sedangkan ibu hamil yang anemia sebesar 154 jiwa (3,62 %). Dari hasil penelitian dari beberapa puskesmas di wilayah Kota Lhokseumawe, bahwa Puskesmas Muara Dua yang masih banyak ibu hamil yang mengalami Anemia.  Berdasarkan data Puskesmas Muara dua Kota Lhokseumawe jumlah ibu hamil 1.786 jiwa dan ibu hamil yang mengalami anemia sebesar 57 orang (3,19%). Penelitian ini bertujuan Untuk mendapat gambaran Faktor-Faktor Yang Mempengaruhi Kepatuhan Ibu Hamil Dalam Mengkonsumsi Tablet Zat Besi Di Wilayah Kerja Puskesmas Muara Dua Kota Lhokseumawe. Jenis penelitian ini adalah penelitian metode survei Analitik dengan pendekatan <em>Cross Sectional Study</em>, populasi dalam penelitian ini ibu hamil yang berada dalam Wilayah kerja Puskesmas Muara Dua Kota Lhokseumawe, yaitu berjumlah 72 orang. Sampel dalam penelitian ini adalah ibu hamil yang berada diwilayah Puskesmas Muara Dua, dan pernah mendapatkan tablet besi. Teknik yang dipakai dalam penelitian ini adalah purposive sampling dengan menggunakan kriteria inklusi. Analisis data<strong> </strong>menggunakan uji <em>Chi-square Test</em> dengan kemaknaan 95 %. Hasil Penelitian menunjukkan frekuensi usia dengan kepatuhan berada pada kategori reproduksi sehat (72,2%), frekuensi pekerjaan dengan kepatuhan berada pada kategori tidak bekerja (65,3%), frekuensi pengetahuan dengan kepatuhan berada pada kategori cukup (75%). Ini menunjukkan ada hubungan antara usia, pekerjaan, dan pengetahuan. Kesimpulan hasil uji statistik <em>Chi-square </em>diketahui nilai tersebut lebih kecil dari alpha (p ≤ 0,05), maka Ha diterima.</p><p><strong>Kata Kunci</strong>       : Ibu Hamil, Kepatuhan, Zat Besi.</p>

scholarly journals HUBUNGAN PENGETAHUAN IBU DAN CARA PERAWATAN TALI PUSAT DENGAN LAMANYA PELEPASAN TALI PUSAT PADA BAYI BARU LAHIR DI KOTA BATURAJA KABUPATEN OKU TAHUN 2019

Masker Medika ◽  
2020 ◽  
Vol 8 (1) ◽  
pp. 53-57
Author(s):  
Ita Haryanti
Keyword(s):  
World Health Organization ◽  
Umbilical Cord ◽  
Survey Methods ◽  
World Health ◽  
P Value ◽  
Maternal Knowledge ◽  
Chi Square ◽  
Cross Sectional ◽  
Chi Square Test ◽  
Health Organization

Latar belakang: Menurut World Health Organization (WHO) Pada tahun (2014) menemukan ada sekitar 300.000 ibu yang memiliki pengetahuan yang rendah terhadap perawatan tali pusat, selain itu didapatkan jumlah bayi yang mengalami infeksi tali pusat sekitar 240.000. Tujuan dari penelitian ini yaitu diketahuinya hubungan pengetahuan ibu dan cara perawatan tali pusat dengan lama pelepasan tali pusat pada bayi baru lahir Di Wilayah kota Baturaja Kabupaten Ogan Komering Ulu Tahun 2019. Metode : peneliti menggunakan metode survey analitik, yaitu peneliti yang mencoba menggali bagaimana dan mengapa fenomenakesehatan ibu terjadi. Surve analitik ini menggunakan pendekatan cross sectional yaitu suatu penelitian untuk mempelajari dinamika korelasi antara faktor-faktor resika dengan efek, dengan cara pendekatan, observasi atau pengumpulan data sekaligus pada suatu saat. Hasil penelitian : Dari hasil penelitian dapat dilihat bahwa lamanya pelepasan tali pusat secara cepat yang berpengatahun tinggi sebesar (85,4%). Sedangkan lamanya pelepasan tali pusat yang berpengetahuan rendah sebesar (40,0%).Hasil analisa bivariat uji chi-square didapatkan p value 0,009. Kesimpulan : ada hubungan antara pengetahuan ibu dan cara perawatan tali pusat dengan lamanya pelepasan tali pusat pada bayi baru lahir.   Background : according to the world health organization (WHO) in (2014) there were around 300,000 mothers who had low knowledge of umbilical cord care, in addition it was found that the number of babies with umbilical cord infections was around 240,000.To find out the length of umbilical cord release in newborns. Research methods : use analytic survey methods,namely research who try to explore how and why the phenomenon of maternal health occurs.this analtic survey uses a cross sectional apporoach wich is a study to study the dynamic of the correlation between risk factors and effects by means of an approach Observation or data : collection at a time at on time results of research from the results of the study can be seen that the length of rapid release of the umbilical cord with high years of age is (85,4%). While the length of umbilical cord removal with low knowledge 40,0%) the results of the bivariate analiysis of the chi-square test obtained p value 0,009. Conclusion : There ia a relationship between maternal knowledge and how to care for the umbilical cord with the length of umbilical cord removal in newborns.

scholarly journals Evaluating antibiotic use and developing a tool to optimize prescribing in a family-centered HIV clinic in Eswatini

PLoS ONE ◽  
2021 ◽  
Vol 16 (1) ◽  
pp. e0244247
Author(s):  
Tara E. Ness ◽  
Ashish E. Streatfield ◽  
Tandzile Simelane ◽  
Abiy Korsa ◽  
Sandile Dlamini ◽  
...  
Keyword(s):  
Initial Period ◽  
Antibiotic Use ◽  
World Health ◽  
Antimicrobial Use ◽  
Chi Square ◽  
Immunodeficiency Virus ◽  
Before And After ◽  
Chi Square Test ◽  
Health Organization ◽  
Family Centered

In a human immunodeficiency virus (HIV) clinic for children and their families in Eswatini, we sought to understand the use of antibiotics and identify specific areas for improvement. We performed a retrospective patient chart review as part of a quality improvement (QI) initiative to assess antimicrobial use before and after implementation of a standardized antimicrobial guide. For each prescribing period, 100 random patient encounters were selected for review if the indication for antibiotics, duration, and dose were consistent with World Health Organization (WHO) guidelines. Two physicians reviewed each encounter using a structured abstraction tool, with a third resolving discrepancies. Results were analyzed using a chi-square test of proportions and a structured survey was performed to assess perceptions of the guide. After the implementation of an antimicrobial guide, there was a significant decrease in the proportion of clinic visits with an antibiotic prescribed (p < 0.001). Incorrect indication for antimicrobial use decreased from 20.4% in the initial period to 10.31% and 10.2% but did not reach significance (p = .0621) in the subsequent periods after implementation. Incorrect dose/duration decreased from 10.47% in the initial period to 7.37% and 3.1% in the subsequent periods, but this was also was not significant (p = 0.139). All prescribers who completed the survey felt that it positively impacted their prescribing. Our study found that an antimicrobial guide reduced and improved the prescription of antimicrobials, demonstrating practical solutions can have a lasting impact on prescribing in low resource settings.

scholarly journals Food insecurity arises the likelihood of hospitalization in patients with COVID-19

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Mohammad Ariya ◽  
Jalal Karimi ◽  
Somayeh Abolghasemi ◽  
Zeinab Hematdar ◽  
Mohammad Mehdi Naghizadeh ◽  
...  
Keyword(s):  
Food Security ◽  
Food Insecurity ◽  
Recovery Period ◽  
Length Of Hospital Stay ◽  
Cross Sectional Study ◽  
World Health ◽  
Chi Square ◽  
Cross Sectional ◽  
Chi Square Test ◽  
Health Organization

AbstractThe World Health Organization (WHO) has declared the Corona pandemic as a public health emergency. This pandemic affects the main pillars of food security. This study aimed to investigate the relationship between food insecurity and the probability of hospitalization and the length of the recovery period after getting COVID-19. The cross-sectional study was performed through the census on COVID-19 patients diagnosed in Fasa, Iran. Informed consent, demographic, and food security questionnaire were completed over the phone. Then, all patients were followed up until recovery. Data were analyzed using SPSS26 and Chi-square test, t-test, and logistic regression (P < 0.05). In this study, 219 COVID-19 patients [100 (54.7%) male and 119 (54.3%) female] with a mean age of 40.05 ± 15.54 years old were examined. Possibility of hospitalization and the length of the recovery period of more than one month was significantly longer in the food-insecure group (P = 0.001) and (P = 0.37), respectively, but the mean length of hospital stay in the two groups was not significantly different (P = 0.76). After adjusting for all confounding variables, people with food insecurity were 3.9 times more likely to be hospitalized than those with food security. Overall, we observed that food-insecure people were significantly more likely to be hospitalized than the secure group.

scholarly journals One-sample two-smear versus two-sample two-smear approach for the diagnosis of pulmonary tuberculosis

2018 ◽  
Vol 10 (02) ◽  
pp. 135-139
Author(s):  
T. Jaya Chandra
Keyword(s):  
Pulmonary Tuberculosis ◽  
Sputum Sample ◽  
Control Programme ◽  
World Health ◽  
Chi Square ◽  
Two Samples ◽  
National Tuberculosis ◽  
Chi Square Test ◽  
The Difference ◽  
Health Organization

ABSTRACT BACKGROUND: To evaluate the efficacy of one-sputum sample two-smear approach for the diagnosis of pulmonary tuberculosis (PT). MATERIALS AND METHODS: Data from January 2012 to December 2015 were analyzed to find (1) number of smear positives (SPs) by spot (S) sample with one and two smears; (2) number of SPs by morning (M) sample with one and two smears; and (iii) number of SPs by two samples with two smears, that is, same-day (SS2) and spot morning (SM) approaches. The Chi-square test was used to evaluate the statistical difference in SP cases. RESULTS: With one-sample two-smear approach, the smear positivity (SPT) was 87% and 87.5%, for S and M samples, respectively, for Ziehl–Neelsen (ZN) staining; whereas, SPT was 96% and 97%, respectively, for S and M samples, for fluorescent staining (FS) technique. With two-sample two-smear approach, for ZN staining, SPT was 89% each and for FS technique, SPT was 97% and 99%, respectively, for SS2 and SM approaches. The difference was not statistically significant (P > 0.05) between one- and two-sample approaches in the staining techniques. CONCLUSION: Significant number of SP cases are identified by S sample two-smear approach. Thus, the World Health Organization/Revised National Tuberculosis Control Programme can initiate S sample two-smear approach for the diagnosis of PT.

HUBUNGAN ANTARA PENDIDIKAN DAN PEKERJAAN IBU DENGAN KEJADIAN DIARE PADA BALITA DI PUSKESMAS BASUKI RAHMAT PALEMBANG TAHUN 2011

2019 ◽  
Vol 2 (1) ◽  
Author(s):  
Rini Mayasari Rini Mayasari
Keyword(s):  
Random Sampling ◽  
Health Centers ◽  
World Health ◽  
Bivariate Analysis ◽  
P Value ◽  
Chi Square ◽  
Cross Sectional ◽  
Chi Square Test ◽  
Health Organization ◽  
Sampling Variable

ABSTRACT According to the health of the World Health Organization (WHO) in poor countries and developing countries, mortality in infants and young children from diarrhea about two million children each year, the purpose of this study was to determine the relationship between education and employment to women with the incidence of diarrhea in children in health centers in 2011 Pelembang Basuki Rahmat This study uses survey Cross sectional analytic approach. The population in this study were all mothers who have young children who come to visit the health center Palembang Basuki Rahmat which amounts to 448 people and a random sample random sampling. Variable that is examined in the analysis using univariate and bivariate analysis via Chi-Square test at α = 0.05. The results of univariate analysis showed that mothers who have children diagnosed with diarrhea as many as 94 people (65.7%) and diarrhea are not diagnosed in 49 men (34.3%), mothers with higher education as many as 68 people (47.6%) and low education as many as 75 people (52.4 %) and mothers who worked as many as 91 people (63.6%) and that does not work as many as 52 people (36.4%). The results of bivariate analysis showed that the incidence of diarrhea in toddlers higher education less mothers were 36 (52.9%) compared with the incidence of diarrhea in children with poorly educated mothers as much as 58 (77.3%), the incidence of diarrhea in infants whose mothers work as much as 72 larger (79.1 %) compared with the non-occurrence of diarrhea in infants whose mothers worked were 19 (20.9%). chi-square test showed no significant association between education with incidence of diarrhea (p value = 0.004) and there was a significant association between maternal work (p value = 0.000) with the incidence of diarrhea in health centers Basuki Rahmat Palembang in 2011. Expected to health workers in order to improve health services, especially education about risk factors for the incidence of diarrhea in infants.     ABSTRAK 21       Menurut badan kesehatan world health organization (WHO) di negara negara miskin dan sedang berkembang, kematian pada bayi dan anak anak akibat diare berkisar dua juta anak tiap tahunnya tujuan penelitian ini adalah untuk mengetahui hubungan antara pendidikan dan pekerjaan ibu dengan kejadian diare pada balita di puskesmas basuki rahmat pelembang tahun 2011. Penelitian ini menggunakan metode survey analitik dengan pendekatan Cross Sectional. Populasi dalam penelitian ini adalah semua ibu yang mempunyai anak balita yang datang berkunjung ke puskesmas basuki rahmat Palembang  yang berjumlah 448 orang dan pengambilan sampel secara random sampling. Variable yang di teliti di analisis dengan menggunakan analisis univariat dan bivariat melalui uji Chi-Square pada α = 0,05.  Hasil analisis univariat menunjukkan ibu yang memiliki balita yang terdiagnosa diare sebanyak 94 orang (65.7%) dan yang tidak terdiagnosa diare sebanyak 49 orang ( 34.3%), ibu dengan pendidikan tinggi sebanyak 68 orang (47.6%) dan pendidikan rendah sebanyak 75 orang (52.4%) dan ibu yang bekerja sebanyak 91 orang (63.6%) dan yang tidak bekerja sebanyak 52 orang (36.4%). Hasil analisis bivariat menunjukkan kejadian diare pada balita yang pendidikan ibunya tinggi lebih kecil sebanyak 36 (52.9%) dibandingkan dengan terjadinya diare pada balita dengan ibu berpendidikan rendah sebanyak 58 (77.3%), kejadian diare pada balita yang ibunya bekerja lebih besar sebanyak 72 (79.1%) dibandingkan dengan tidak terjadinya diare pada balita yang ibunya bekerja sebanyak 19 (20.9%). uji chi-square menunjukkan ada hubungan yang bermakna antara pendidikan dengan kejadian diare ( p value = 0,004) dan ada hubungan yang bermakna antara pekerjaan ibu (p value =0,000) dengan kejadian diare di Puskesmas Basuki Rahmat Palembang tahun 2011. Diharapkan kepada petugas kesehatan agar dapat meningkatkan pelayanan kesehatan terutama penyuluhan tentang faktor  resiko kejadian diare pada balita.

scholarly journals Can Gastrointestinal Clinical Presentation Predict Gastroparesis: Results From a Tertiary Referral Center

2011 ◽  
Vol 140 (5) ◽  
pp. S-808
Author(s):  
Mandeep Singh ◽  
Katherine Roeser ◽  
Siddhant Yadav ◽  
Praveen Tripathi ◽  
Zachary Viets ◽  
...  
Keyword(s):  
Clinical Presentation ◽  
Tertiary Referral ◽  
Tertiary Referral Center ◽  
Referral Center

scholarly journals Incidence of Hyperglycemia/Secondary Diabetes in Women who have Undergone Curative Chemotherapy for Breast Cancer: First Study from India

2021 ◽  
Author(s):  
Suresh Rao ◽  
Krishna Prasad ◽  
Soniya Abraham ◽  
Thomas George ◽  
Supreeth Kakkaje Chandran ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Radiation Treatment ◽  
Previous History ◽  
World Health ◽  
Chi Square ◽  
Secondary Diabetes ◽  
Number Of Children ◽  
Glucose Levels ◽  
Chi Square Test ◽  
Health Organization

Abstract Purpose Development of cancer chemotherapy treatment-induced hyperglycemia/ diabetes (secondary diabetes) is a major problem and has never been reported from India. The present study was planned to ascertain this in women undergoing curative chemotherapy for their breast cancer. Materials and Methods This was a retrospective chart-based study and was conducted in a cancer specialty hospital. The information on women who were nondiabetic at the start of the treatment was collected from the files. Details on cancer diagnosis, domicile, body mass index (BMI), type of diet, marital status, number of children, and previous history of diabetes if any were considered. The blood glucose levels before surgery and after the completion of radiotherapy were considered. World Health Organization (WHO) guidelines for diabetes were considered. The data were subjected to frequency and percentage and analyzed using Chi-square test. Association between the demographic details and development of Hyperglycemia or secondary diabetes or prediabetes was done using the Pearson’s correlation analysis. p < 0.05 was considered as statistically significant. Results A total of 474 cases were included in accordance with the inclusion criteria. The results indicated that by the end of the radiation treatment, 24.89% were prediabetic, 10.97% were diabetic after being in prediabetic stage, 8.22% became diabetic without going through a prediabetic stage, and that 55.91% did not develop either prediabetic or diabetic condition. Analysis of development of secondary diabetes and prediabetes with BMI (p < 0.0001) and age (p < 0.024) showed a strong correlation and was significant. Conclusion To the best of the authors’ knowledge, this is the first study from India, and the results indicate that the development of secondary diabetes in women undergoing curative chemotherapy is high. Attempts are underway to ascertain the cause for the development and how it can be mitigated.

Sign in / Sign up

Export Citation Format

Share Document