Hormonal contraception as a method of social adaptation of women in modern society

GYNECOLOGY ◽  
2019 ◽  
Vol 21 (3) ◽  
pp. 17-21
Author(s):  
Tatyana Yu Pestrikova ◽  
Elena A Yurasova ◽  
Igor V Yurasov ◽  
Tamara D Kovaleva
Keyword(s):  
Ethinyl Estradiol ◽  
Hormonal Contraception ◽  
Modern Society ◽  
Well Being ◽  
Social Adaptation ◽  
Female Employment ◽  
Hormonal Contraceptives ◽  
Aim Analysis ◽  
Positive Effects ◽  
Chlormadinone Acetate

Relevance. Currently, women make up more than 40% of the global workforce and more than half of students studying at universities around the world. Women's education, especially at a high level, tends to increase female employment. The mismatch of the style and rhythm of modern life with a genetically determined and working millennium reproductive program requires the choice of a specific approach to social adaptation. Aim. Analysis of literary sources on the use of hormonal contraception as a method of social adaptation. Materials and methods. To write this review, domestic and foreign publications were searched in Russian and international search systems (PubMed, eLibrary, etc.) for the last 2-10 years. The review included articles from peer-reviewed literature. Results. The review describes the features of modern hormonal contraceptives. Their non-contraceptive effects are presented. The individual non-contraceptive effects of a combined oral contraceptive containing 30 mg of ethinyl estradiol and 2 mg of chlormadinone acetate were determined. It has been established that the use of this contraceptive helps to improve the well-being and mood of patients, which allows you to actively use this contraceptive in routine clinical practice with premenstrual syndrome, dysmenorrhea, without the use of analgesics. Conclusions. The numerous positive effects of ethinyl estradiol and chlormadinone acetate allow the use of the drug as a means to increase social adaptation, and, consequently, improve the quality of life.

scholarly journals Portal Venous Thrombosis Associated with Use of Etonogestrel/ethinyl Estradiol Vaginal Ring

2020 ◽  
Vol 4 (2) ◽  
pp. 263-266
Author(s):  
Katelynn Bailey ◽  
Michael Tranovich
Keyword(s):  
Abdominal Pain ◽  
Venous Thrombosis ◽  
Oral Contraceptives ◽  
Ethinyl Estradiol ◽  
Hormonal Contraception ◽  
Vaginal Ring ◽  
Hormonal Contraceptives ◽  
Term Outcome ◽  
Life Threatening ◽  
Portal Venous Thrombosis

Introduction: Portal venous thrombosis is a life-threatening cause of abdominal pain. In younger patients, heritable thrombophilias, pregnancy, tobacco use, and oral contraceptives are associated. Case Report: A 26-year-old woman prescribed contraceptive vaginal ring presented with abdominal pain and was diagnosed with an extensive portal venous thrombosis. Management included heparin and later an oral anticoagulant with good short-term outcome. Discussion: Women using hormonal contraception are approximately four times more likely to develop thromboembolism. Risk of thromboembolism is similar between users of intravaginal and oral contraceptives. Conclusion: Portal venous thrombosis must be considered in women presenting with abdominal pain who are prescribed hormonal contraceptives, including intravaginal forms.

scholarly journals MECHANISMS IN ENDOCRINOLOGY: Epidemiology of hormonal contraceptives-related venous thromboembolism

2014 ◽  
Vol 171 (6) ◽  
pp. R221-R230 ◽  
Author(s):  
Justine Hugon-Rodin ◽  
Anne Gompel ◽  
Geneviève Plu-Bureau
Keyword(s):  
Venous Thromboembolism ◽  
Second Generation ◽  
Ethinyl Estradiol ◽  
Hormonal Contraception ◽  
Current Data ◽  
Biological Data ◽  
Sex Hormone Binding Globulin ◽  
Hormonal Contraceptives ◽  
Low Doses ◽  
Thrombotic Risk

For many years, it has been well documented that combined hormonal contraceptives increase the risk of venous thromboembolism (VTE). The third-generation pill use (desogestrel or gestodene (GSD)) is associated with an increased VTE risk as compared with second-generation (levonorgestrel) pill use. Other progestins such as drospirenone or cyproterone acetate combined with ethinyl-estradiol (EE) have been investigated. Most studies have reported a significant increased VTE risk among users of these combined oral contraceptives (COCs) when compared with users of second-generation pills. Non-oral combined hormonal contraception, such as the transdermal patch and the vaginal ring, is also available. Current data support that these routes of administration are more thrombogenic than second-generation pills. These results are consistent with the biological evidence of coagulation activation. Overall, the estrogenic potency of each hormonal contraceptive depending on both EE doses and progestin molecule explains the level of thrombotic risk. Some studies have shown a similar increased VTE risk among users of COCs containing norgestimate (NGM) as compared with users of second-generation pill. However, for this combination, biological data, based on quantitative assessment of sex hormone-binding globulin or haemostasis parameters, are not in agreement with these epidemiological results. Similarly, the VTE risk associated with low doses of EE and GSD is not biologically plausible. In conclusion, newer generation formulations of hormonal contraceptives as well as non-oral hormonal contraceptives seem to be more thrombogenic than second-generation hormonal contraceptives. Further studies are needed to conclude on the combinations containing NGM or low doses of EE associated with GSD.

Clinical relevance in present day hormonal contraception

2018 ◽  
Vol 37 (1) ◽  
Author(s):  
Pedro-Antonio Regidor
Keyword(s):  
Ethinyl Estradiol ◽  
Hormonal Contraception ◽  
Active Agent ◽  
Hormonal Contraceptives ◽  
Therapeutic Effects ◽  
Mode Of Application ◽  
Ovulation Inhibition ◽  
Vaginal Rings ◽  
Long Acting ◽  
Combined Hormonal Contraceptives

Abstract The contraceptive pill is an effective and very safe method to control pregnancies. It was developed 60 years ago, and despite that the composition has been the same since it was first developed (estrogen and progestogen), over the years the concentration of ethinyl estradiol has been reduced to improve tolerability. Nevertheless, progestogens are the basic active agent of hormonal contraception. The mechanism of progestogens is a multimodal one and basically three modes of contraceptive action can be distinguished: (a) A strong antigonadotrophic action leading to the inhibition of ovulation. The necessary dosage of ovulation inhibition per day is a fixed dosage that is intrinsic to each progestogen and independent of the dosage of estrogen used or the partial activities of the progestogen or the mode of application. (b) Thickening of the cervical mucus to inhibit sperm penetration and (c) desynchronization of the endometrial changes necessary for implantation. The on the market available progestogens used for contraception are either used in combined hormonal contraceptives (in tablets, patches or vaginal rings) or as progestogen only contraceptives. Progestogen only contraceptives are available as daily oral preparations, monthly injections, implants (2–3 years) and intrauterine systems (IUS). Even the long-acting progestogens are highly effective in typical use and have a very low risk profile. According to their introduction into the market, progestogens in combined hormonal contraceptives, have been described as 1st, 2nd, 3rd and 4th generation progestogens. The different structures of progestogens are derivatives from testosterone, progesterone and spironolactone. These differences in the molecular structure determine pharmacodynamic and pharmacokinetic differential effects which contribute to the tolerability and additional beneficial or therapeutic effects whether used in combined oral contraceptive (COC) or as progestogen only drugs. These differences enhance the individual options for different patient profiles. The new development of polymers for vaginal rings allowed on the one hand, the improvement of the estrogen/progestogen combination in these rings especially regarding the comfort of use for women (e.g. avoiding the use of cold chains or packages with up to 6-month rings) and on the other hand, the development of progestogen only formulations. Another future development will be the introduction of new progestogen only pills that will provide effective contraceptive protection with more favorable bleeding patterns and a maintenance of ovulation inhibition after scheduled 24-h delays in pill intake than the existing progestogen only pill (POP) with desogestrel (DES).

scholarly journals Infectious illnesses of young children: financial burden for rich countries - a literature review

2021 ◽  
Vol 31 (Supplement_3) ◽  
Author(s):  
J Graichen
Keyword(s):  
Cost Of Illness ◽  
Economic Burden ◽  
Financial Burden ◽  
Well Being ◽  
Kindergarten Children ◽  
Female Employment ◽  
Efficient Design ◽  
Positive Effects ◽  
Hospitalization Costs ◽  
Cost Efficient

Abstract   While childcare assistance has indisputable positive effects on female employment and economic growth, children attending day care centres show a considerably higher number of infections compared to those raised at home. This is not only a substantial threat to the well-being of families, but also a major economic burden for society. This review aims at examining studies that describe and quantify the costs of illnesses that are possibly transmitted in kindergarten to enable development of policies and interventions. A scientific literature search was performed. The electronic databases PubMed and Medline were searched with keywords and MeSH terms (Cost of Illness; Health Care Costs; Child). Articles were considered relevant, if published after the year 2000 in English, if conducted in Europe, USA or Australia, examining contagious illnesses (respiratory, influenza(-like), gastrointestinal diseases) of children and if not solely focused on hospitalization costs. A total of 504 records were identified. After abstract and full text screening, 15 articles were selected. No article summarizes all illnesses that are possibly transmitted in kindergarten, studies rather estimate costs for one diagnosis or one symptom group only. Main cost buckets considered are direct medical, direct non-medical and indirect costs (mainly due to loss of workdays of caregivers). Focus and perspective of the studies and thus the quantification of costs differs widely (e.g., for respiratory illnesses per non-hospitalized case one study claims 123 vs. 49 Euro in neighbouring countries). Existing cost of illness studies cannot easily be combined to one overall cost estimation for sick kindergarten children, which is needed to foster public health actions and to enable cost-efficient design. However, solely looking at single illnesses already reveals the big potential which comes with reducing contagious illnesses in the child age and thus, the urgent need to action to relieve children and society. Key messages The economic burden arising from contagious illnesses among kindergarten children is substantial and reveals the need for policies and interventions to relieve children and society. Further research is needed to get a comprehensive view of cost of illnesses for children with illnesses transmitted in kindergarten to enable cost-efficient design of interventions.

Contraception and thrombophilia

2009 ◽  
Vol 29 (02) ◽  
pp. 193-196 ◽  
Author(s):  
H. Rott ◽  
A. Kruempel ◽  
G. Kappert ◽  
U. Nowak-Göttl ◽  
S. Halimeh
Keyword(s):  
Chronic Illness ◽  
High Risk ◽  
Children And Adolescents ◽  
Hormonal Contraception ◽  
Hormonal Contraceptives ◽  
Thromboembolic Events ◽  
Contraceptive Methods ◽  
Secondary Complications ◽  
Increased Risk ◽  
Coagulation Proteins

SummaryThe risk of thromboembolic events (TE) is increased by acquired or inherited thrombo -philias (IT). We know that some hormonal contraceptives also increase the risk of thrombosis, thus, the use of such contraceptives are discussed as contraindications in women with IT. TEs are infrequent events in children and adolescents and in the majority of cases are associated with secondary complications from underlying chronic illness. Although adolescents are not typically considered to be at high-risk for TE, this cohort is frequently using hormonal contraception, leading to an increased risk in cases with unknown IT. The risk of TE with pregnancy alone is higher than associated with combined hormonal contra -ception. Progestin-only methods have not been found to increase the risk of TE with only moderate changes of coagulation proteins compared to normal reference values. Conclusion: Thrombophilic women are good candidates for progestin-only contraceptive methods.

Place of progestogenic oral contraceptives in gynecological practice

2019 ◽  
Vol 1 (1) ◽  
pp. 19-26
Author(s):  
I. V. Kuznetsova
Keyword(s):  
Venous Thrombosis ◽  
Oral Contraceptives ◽  
Hormonal Contraception ◽  
Review Of The Literature ◽  
Safety Issues ◽  
Routes Of Administration ◽  
Positive Effects ◽  
Combined Hormonal Contraception

The review of the literature presents data on the possible risks of using combined hormonal contraception and the possibilities of prescribing purely progestogenic contraception as an alternative to the use of combined means. Progestogen contraceptives include a group of agents with different routes of administration, doses and characteristics of progestins, which have a number of differences in the ratio of benefits and risks, availability, reversibility and other properties of contraception. Particular attention is paid to purely progestogenic tablets containing desogestrel, as a means equivalent in effectiveness to combination contraceptives, but safer. Safety issues are considered in the context of the use of breastfeeding women, as well as from the standpoint of the risk of arterial and venous thrombosis. The issues of non-contraceptive positive effects of purely progestogenic contraceptives are covered.

scholarly journals Transition from Emotional to Rational Advertising for Food Products on the Romanian Market

2017 ◽  
Vol 50 (1) ◽  
pp. 101-108
Author(s):  
A.F. Jităreanu ◽  
Elena Leonte ◽  
A. Chiran ◽  
Benedicta Drobotă
Keyword(s):  
Urban Areas ◽  
Eating Habits ◽  
Well Being ◽  
Point Of View ◽  
The Body ◽  
Positive Effects ◽  
New Methods ◽  
Brand Advertising ◽  
Tangible Evidence ◽  
Health And Well Being

Abstract Advertising helps to establish a set of assumptions that the consumer will bring to all other aspects of their engagement with a given brand. Advertising provides tangible evidence of the financial credibility and competitive presence of an organization. Persuasion is becoming more important in advertising. In marketing, persuasive advertising acts to establish wants/motivations and beliefs/attitudes by helping to formulate a conception of the brand as being one which people like those in the target audience would or should prefer. Considering the changes in lifestyle and eating habits of a significant part of the population in urban areas in Romania, the paper aims to analyse how brands manage to differentiate themselves from competitors, to reposition themselves on the market and influence consumers, meeting their increasingly varied needs. Food brands on the Romanian market are trying, lately, to identify new methods of differentiation and new benefits for their buyers. Given that more and more consumers are becoming increasingly concerned about what they eat and the products’ health effects, brands struggle to highlight the fact that their products offer real benefits for the body. The advertisements have become more diversified and underline the positive effects, from the health and well - being point of view, that those foods offer (no additives and preservatives, use of natural ingredients, various vitamins and minerals or the fact that they are dietary). Advertising messages’ diversification is obvious on the Romanian market, in the context of an increasing concern of the population for the growing level of information of some major consumer segments.

scholarly journals Effects of Evocative Audio-Visual Installations on the Restorativeness in Urban Parks

2021 ◽  
Vol 13 (15) ◽  
pp. 8328
Author(s):  
Massimiliano Masullo ◽  
Luigi Maffei ◽  
Aniello Pascale ◽  
Vincenzo Paolo Senese ◽  
Simona De Stefano ◽  
...  
Keyword(s):  
Social Inclusion ◽  
Road Traffic ◽  
Traffic Noise ◽  
Human Perception ◽  
Urban Parks ◽  
Well Being ◽  
Road Traffic Noise ◽  
Beneficial Effects ◽  
Positive Effects ◽  
Experimental Laboratory

Road traffic noise is responsible for several negative health effects for citizens in modern cities. Inside urban parks, which citizens use for social inclusion and cohesion, psychological and physical restoration, and physical activities, road traffic noise may significantly reduce the potential of these places to induce or enhance well-being. Although access restriction schemes and screens could be effective solutions to limit noise inside urban park areas, preserving their potential regenerative role may engender mobility, social, aesthetic, and architectural issues. Due to the positive effects that natural elements and water sounds can have on human perception, and based on the previous findings of the beneficial effects of audio-visual installations, this paper investigates the possibility of using audio-visual installations that simply evoke some natural features to improve the restoration of individuals inside urban parks. The study has been carried out using immersive virtual environments in two different experimental laboratory sessions in Hong Kong (China) and Aversa (Italy). The results showed that the positive effects provided by evocative installations were similar to those provided by traditional installations. Furthermore, the effects on the restoration increased as the installations became larger and included enveloping shapes. Furthermore, we found that the amount of evocative water installations’ material was responsible for changes in restoration. In contrast, the Chinese groups were less influenced by these installations.

scholarly journals The opportunity of shared autonomous vehicles to improve spatial equity in accessibility and socio-economic developments in European urban areas

2021 ◽  
Vol 13 (1) ◽  
Author(s):  
Norman Eppenberger ◽  
Maximilian Alexander Richter
Keyword(s):  
Educational Attainment ◽  
Unemployment Rate ◽  
Public Transport ◽  
Public Transportation ◽  
Autonomous Vehicles ◽  
Well Being ◽  
District Level ◽  
Positive Effects ◽  
Spatial Equity ◽  
Economic Well Being

Abstract Background This paper provides insight into the opportunity offered by shared autonomous vehicles (SAVs) to improve urban populations’ spatial equity in accessibility. It provides a concrete implementation model for SAVs set to improve equity in accessibility and highlights the need of regulation in order for SAVs to help overcome identified spatial mismatches. Methodology Through the formulation of linear regression models, the relationship between land-use and transportation accessibility (by car and public transport) and socio-economic well-being indicators is tested on district-level in four European cities: Paris, Berlin, London and Vienna. Accessibility data is used to analyse access to points of interest within given timespans by both car and public transport. To measure equity in socio-economic well-being, three district-level proxies are introduced: yearly income, unemployment rate and educational attainment. Results In the cities of Paris, London and Vienna, as well as partially in Berlin, positive effects of educational attainment on accessibility are evidenced. Further, positive effects on accessibility by yearly income are found in Paris and London. Additionally, negative effects of an increased unemployment rate on accessibility are observed in Paris and Vienna. Through the comparison between accessibility by car and public transportation in the districts of the four cities, the potential for SAVs is evidenced. Lastly, on the basis of the findings a ‘SAV identification matrix’ is created, visualizing the underserved districts in each of the four cities and the need of equity enhancing policy for the introduction of SAVs is emphasized.

Non-stigmatising alternatives to anti-obesity public health messages: Consequences for health behaviour and well-being

2021 ◽  
pp. 135910532199970
Author(s):  
Joanne A Rathbone ◽  
Tegan Cruwys ◽  
Jolanda Jetten
Keyword(s):  
Public Health ◽  
Weight Loss ◽  
Experimental Studies ◽  
Health Behaviours ◽  
Well Being ◽  
Health Messages ◽  
Total N ◽  
Positive Effects ◽  
Public Health Messages ◽  
Size Acceptance

This project investigated how alternative non-stigmatising public health messages influence people’s health behaviours and well-being, relative to traditional stigmatising weight-loss messages. We conducted three experimental studies (total N = 1281) that compared traditional weight-loss messages to weight-neutral messages (Study 1), weight-inclusive messages (Study 2) and size acceptance messages (Study 3). Results revealed that public health messages have differential effects on health behaviours and well-being, depending on the audience’s BMI or perceived weight. However, campaigns that challenge weight stigma and promote body positivity have positive effects on some psychological indicators of health and well-being for people of all body sizes.

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