An efficient approach on alcohol dependence syndrome

Author(s):  
Thejaswini Karanth ◽  
Someswar Deb ◽  
Pranathi R ◽  
Kasthuri P

Alcohol consumption results in multiple end-organ damages. Predominantly the nervous system is affected in the form of Wernicke encephalopathy, Korsakoff psychosis, cerebellar ataxia and peripheral neuropathy. Neuropathy due to alcohol consumption depends on the period and extent of total lifetime of alcohol consumption. Cultural and racial factors also play a role in the development of alcohol neuropathy. Alcohol consumption results in multiple end-organ damages. Alcoholic neuropathy is the most common harmful effects of excessive alcohol intake. The incidence of alcoholic neuropathy in the standard population is not accurate as the percentage varies extensively contingent on the description of chronic alcoholism and the criteria used to detect and classify neuropathy. According to the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition (DSM-IV), studies involving clinical and electrodiagnostic tests prove that neuropathy is present in 25-66%. Alcoholic neuropathy depends on the extent and extent of total lifetime of alcohol consumption. Cultural and racial factors also play a role in resulting in alcohol neuropathy. Few studies suggest that the incidence of peripheral neuropathy is higher in alcoholic patients who have a family history of alcohol dependence syndrome. This is study finds the Common peroneal and sural nerves are the most common nerves to be involved in neuropathy. Predominantly axonal degeneration is the main pathology. Units of alcohol and CAGE criteria score has a 100% specificity in detecting patients prone to neuropathy.

2019 ◽  
Vol 63 (2) ◽  
pp. 79-85
Author(s):  
Raisa Ya. Khamitova ◽  
D. V. Loskutov

Introduction. There are variable patterns of alcohol consumption in Russia that differ significantly between the regions. Awareness and knowledge of those regional differences are key to the effectiveness of measures to prevent and minimise possible damage to public health caused by alcohol consumption. The purpose. To identify regional characteristics of the dynamics of alcoholism and alcoholic psychosis and dependencies with indicators of the implementation and consumption of alcohol in Mari El in 2006-2017. Material and methods. In a retrospective analysis, they included state statistics and bulletins of the Office of Rospotrebnadzor on RME on the primary incidence and prevalence of alcohol dependence syndrome, chronic alcoholism, AP, acute alcohol poisoning, sales of alcohol through a distribution network in 2006-2017. Results. In the reported period of 2006-2017 there was a decline in determination coefficient (R2) from 0.76 to 0.96 for newly diagnosed cases of alcohol dependence in general, alcoholic psychosis and alcoholism in Mari El. There was a significant decline from 221.6 to 47.5 per 100 thousand in the range of values between regions, but higher rates remained among the rural and urban areas (p = 0.0002). The dynamics of the prevalence of alcoholic psychotic disorders and alcoholism were also on decline. Conclusion. The direction and extent of changes in the medical consequences of alcohol consumption (such as primary morbidity and prevalence of alcohol dependence syndrome, alcoholic psychosis and alcoholism, average duration of the course, number of alcoholic psychosis) in the region and indicators of the implementation and consumption of alcoholic beverages in the reported period can be evaluated as positive. It is crucial to ensure the positive trend in the alcohol consumption pattern and impact on public health in the region becomes a long-lasting one. At the same time, it is necessary to increase attention to the assistance and treatment provided to drug users patient.


2021 ◽  
Vol 26 (1) ◽  
pp. 52-57
Author(s):  
K. A. Kunavina ◽  
A. S. Opravin ◽  
A. G. Soloviev ◽  
O. A. Harkova ◽  
N. V. Davidovich

Relevance. Oral health problems, particularly periodontal diseases, are frequent complications in people with alcohol dependence syndrome (ADS). The assessment of the periodontal, immune status and the tongue condition in ADS patients by the set of indices is promising. Materials and methods. The periodontal and immune status and the tongue condition were examined in 114 men, of whom 47 were patients with stage II ADS and 67 were subjects without a history of ADS. Pearson's chi-squared test, Mann–Whitney U test, logistic regression, factor analysis were used for statistical analysis. Results. ADS patients have significantly worse oral hygiene (p < 0.001) and 35.5 times higher probability of moderate to severe gum inflammation (p < 0.001). Sextants with bleeding (39.0%) and calculus (25.9%) prevailed among ADS patients whereas most of sextants were healthy (85.8%) in the comparison group. Significant inter-group differences were found for all CPI codes except code 4 (p < 0.001). The dorsal surface tongue coating (63.8%) and minor hyperkeratosis (27.7%) prevailed among ADS patients, while in the comparison group, there were no changes in 34.3% of subjects and coating was present in 38.8% (p = 0.003). The risk of satisfactory to poor oral hygiene was 3.7 times (p = 0.007) higher and the risk of moderate to severe gum inflammation was predicted to be 6.5 times (p = 0.015) higher if the examined subjects had changes in the tongue mucosa. The obtained differences in the level of IgG, TNF-α and cortisol prevailed in ADS patients (p < 0.001). Conclusion. In ADS patients, the severity of periodontal diseases, changes in the tongue mucosa and mucosal immunity imbalance are statistically significant. The considered dental markers of chronic alcohol intoxication are proposed to be used at the treatment and checkup dental visits to screen individuals at risk of alcohol use disorder.


2003 ◽  
Vol 20 (2-3) ◽  
pp. 101-111
Author(s):  
Anders Romelsjö ◽  
Robin Room ◽  
Elisabeth Ellström

Several studies have been done on the prevalence of the alcohol dependence syndrome, while other studies have focused on whether the dependence syndrome can be seen as a unity, or not. Few studies have analysed the association between alcohol consumption, the alcohol dependence syndrome (ADS) and alcohol-related problems. A main issue is to what extent an association between alcohol consumption and problems is explained by the dependence syndrome or by its sub-components (drinking despite a health problem, craving, impaired control, preoccupation with alcohol, withdrawal symptoms and increased tolerance). The purpose in this paper is to elucidate this issue in analyses of data from the health care-based clinical sample of the study “Women and Men in Swedish Addiction Treatment”, comprising comprehensive interviews of almost 1000 inpatients and outpatients in Stockholm County. These data cover e.g. alcohol and drug use, alcohol dependence (ICD-10) measured by the Composite International Diagnostic Interview (CIDI), the composite-scores part of the Addiction Severity Index (ASI), sociodemographics and alcohol-related problems. Three measures of alcohol-related problems were constructed covering health and psychological problems, self-defined social problems, and social problems defined by others. In these exploratory analyses of patients with alcohol dependence as a dominating problem, a series of logistic regression analyses were done. A substantial part of the association between the consumption measures and the three outcomes could be accounted for by measures of the ADS. The predictive power of the six criteria composing the ADS varied considerably for the different outcomes. The interpretation is not straightforward, not least as the alcohol dependence syndrome also includes items of alcohol-related problems.


Author(s):  
O. S. Litvinovа ◽  
M. V. Kalinovskaya

The article presents results of assessing data on morbidity attributable to chronic alcoholism and drug addiction among teenagers over Russia, in federal districts and subjects of the Russian Federation over 2011-2915. The data are reported by the Federal Information Fund of Socio-Hygienic Monitoring, set up by the Federal Hygienic and Epidemiological Center of Rospotrebnadzor In the Russian Federation in 2015the incidence of the of alcohol dependence syndrome(alcoholism) in adolescents aged of 15to 17years was 2.98per 100thousand ; this value for adolescents of the same age was 5.6g.b. 5.65 in 2014, 3.74in 2013, 5.13in 2012, 9.50in 2011). As compared with 2011, in 2015the incidence of alcohol dependence among adolescents significantly decreased by 3.2-fold((P


2015 ◽  
Vol 23 (12) ◽  
pp. 1497-1504 ◽  
Author(s):  
Carlos Roncero ◽  
Lluisa Ortega ◽  
Jesús Pérez-Pazos ◽  
Anna Lligoña ◽  
Alfonso C. Abad ◽  
...  

Objective: To estimate the prevalence of ADHD in adult patients treated for alcohol dependence and to analyze the characteristics of consumption and psychiatric comorbidity, in function of a possible ADHD in adulthood. Method: We administered the Adult ADHD Self-Report Scale (ASRS) to 726 alcohol-dependent patients. Clinical diagnosis, following Diagnostic and Statistical Manual of Mental Disorders (4th ed., text rev.; DSM-IV-TR) criteria was made in the first four weeks of treatment. A subsample of 297 patients was evaluated using Conners’ Adult ADHD Diagnostic Interview for DSM-IV (CAADID-II) to test the psychometric properties of ASRS. Results: After analyzing the properties of the ASRS (sensitivity: 83.3%; specificity: 66.1%), the prevalence of ADHD, in the whole sample, was estimated to be 16.2%. Being younger, lifetime history of cocaine dependence and the presence of an affective, anxiety or personality disorder were associated with a possible ADHD. Conclusion: The estimated prevalence of ADHD in patients being treated for alcohol dependence is high, and the presence of a possible ADHD in adulthood is associated with an increase in psychiatric comorbidity.


Author(s):  
NEERAJ J KARANDIKAR ◽  
PRITISH K RAUT ◽  
PRASAD K TAGAD

Background: Alcohol abuse is one of the major causes of death and disability globally; and a key risk factor for health, social, and economic problems in the communities. Consumption of alcohol by Indians has increased drastically due to various factors and in an unrestricted manner; and the age of initiation of drinking is progressively coming down. Objective: To determine the socio-demographic and clinical profile of the patients coming for treatment of alcohol dependence syndrome in the psychiatry department. Methods: A cross-sectional study was conducted on 50 male outpatients of alcohol dependence syndrome attending the department of psychiatry at a tertiary care hospital. Sociodemographic data and clinical details were recorded with the help of a pre-designed questionnaire. Results: Nuclear family, family history of alcoholism, unmarried status, higher educational level, unemployment, and peer pressure are the factors significantly associated with early age at first drink and age of dependence on alcohol (p < 0.05). Conclusion: Adolescents having a family history of alcoholism are a high-risk group for developing alcohol dependence and should be targeted for intervention strategies. Community based-longitudinal studies are needed to understand multiple factors influencing alcohol use and recommend targeted preventive measures. Keywords: Alcohol, Alcohol dependence syndrome, Peer pressure, Intoxication, Socio-demographic factors


Author(s):  
Arvind Visweshwar ◽  
Mohamed Hanifah ◽  
. Murugesan ◽  
. Avudaiappan ◽  
Arun Prakash

Aim: To detect the prevalence of asymptomatic neuropathy using nerve conduction study among alcohol dependence syndrome patients and to investigate the existence or not of correlation between duration, quantity of alcohol consumption and neuropathy. Study Design: Observational cross-sectional study. Place and Duration of Study: Department of General Medicine and Department of Psychiatry, Mahatma Gandhi Medical College and Research Institute, Pondicherry, affiliated to Sri Balaji Vidyapeeth (Deemed to be) University, India between February 2019 and August 2020. Methods: Alcohol dependence syndrome patients, asymptomatic for neuropathy were prospectively included and, patients who were symptomatic and had other comorbid conditions that can cause neuropathy were excluded. Patients were then submitted to nerve conduction studies. In patients who had neuropathy, duration and quantity of alcohol consumption were compared for correlation. Results: This study included 65 male patients who were mostly middle aged heavy drinkers of alcohol. 73.8% (n=48) had neuropathy. Our research showed longer the duration, larger the quantity of alcohol consumption, and higher the Cut-Annoyed-Guilty-Eye (CAGE score), more were the prevalence of neuropathy. This research also used Severity Of Alcohol Dependence Questionnaire (SAD-Q) scoring for screening alcohol dependence which showed patients with neuropathy were moderate drinkers. We did not find correlation with age of patients and neuropathy. Conclusion: This research results like correlation of prevalence of neuropathy and duration of alcohol consumption and quantity of alcohol consumption were in contrast with previous studies on alcoholic neuropathy. This research used SAD-Q scoring for dependence, future researches can throw light on usage of SAD-Q score in asymptomatic neuropathy and the correlation of neuropathy with alcohol consumption.


1996 ◽  
Vol 13 (1) ◽  
pp. 28-30 ◽  
Author(s):  
Barbara Farragher ◽  
Miriam Gannon ◽  
Ishtag Ahmad

AbstractObjective: To quantify the number of patients absent without leave (AWOL) from an Irish psychiatric hospital in one year and to examine the clinical and demographic data of this group of patients.Method: This was a retrospective study of all patients reported as AWOL from St Brendan's Hospital in 1991. The following information was obtained from the patients' case notes: age, sex, legal status, marital status, psychiatric diagnosis, number of previous admissions, past history of absconding, length and outcome of absence. Their clinical and demographic variables were compared with a control group of 214 patients (non-absconders) randomly selected from the hospital admissions over a 12 month period.Results: A total of 48 patients absconded. The majority were male, single, compulsorily detained, with a past history of absconding. The most common psychiatric diagnoses were schizophrenia (32%), personality disorder (23%) and alcohol dependence syndrome (17%). While absent, three patients had a history of suicidal behaviour and four became involved in criminal activity. Compulsory status was statistically significant when compared to the control group.Conclusion: The characteristics of our group of absconders are similar to those in previous studies apart from the increased prevalence of personality disorder and alcohol dependence syndrome. We discuss the risks associated with absconding and recommend close follow-up of this group of patients.


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