scholarly journals Association between increasing age, obesity and heredity with osteoarthritis of knee joint among middle aged and old aged population

2020 ◽  
Vol 11 (SPL3) ◽  
pp. 765-772
Author(s):  
Harita Ravikumar ◽  
Karthik Ganesh Mohanraj ◽  
Don K R

Osteoarthritis is one of the major problems that are faced by the people in developed countries but also present all over the world. There are so many factors that affect the cause of osteoarthritis, majorly it is found to be age, sex, occupation and much more. The increase in BMI can increase the probability of development of osteoarthritis. The study has been conducted among the Chennai population involving 100 participants. Self-administered questionnaire is circulated through online mode and the responses have been collected. It was observed that the majority of the people participated were aware of osteoarthritis and that obesity, heredity and age are the major cause of osteoarthritis of the knee joint. It is concluded that people though have awareness of osteoarthritis, the knowledge about the risk factors, the effects and future problems caused by knee joint osteoarthritis remains sparse among the population. the probable risk factors of knee osteoarthritis such as age, sedentary lifestyle and obesity, unhealthy diet and heredity seems to play a key role in knee OA and has to be considered seriously for the prevention and management of this disease. Upon considering these aspects people can have a good approach towards the disease and its management which serves as the basic requirement of proper lifestyle for betterment of life.

2015 ◽  
Vol 6 (3) ◽  
pp. 99-124
Author(s):  
Ishu Kataria ◽  
Ravinder Chadha ◽  
Renuka Pathak

Metabolic syndrome is a constellation of risk factors that has the potential of developing into cardiovascular disease or increase the susceptibility to it. It is present worldwide with now even developing countries getting overwhelmed by its burden. With a shift towards unhealthy diet coupled with sedentary lifestyle, development of metabolic syndrome is on the rise even among young adults. One of the main causes of this problem is faulty diet, so any means to reduce the incidence of the syndrome involves the modification of the existing diets rich in saturated fat, sodium and cholesterol. This review focusses on efficacy of different dietary patterns for combating the syndrome along with other lifestyle risk factors. It also highlights newer advancements in the field of Metabolic Syndrome, which can serve as potential strategies to combat it. Public health interventions targeting adults, therefore, should center on prevention through education, modification of diet and lifestyle, and focusing on environment, so that these changes are acceptable and sustainable.


2020 ◽  
Author(s):  
Shuang Zheng ◽  
Liudan Tu ◽  
Flavia Cicuttini ◽  
Zhaohua Zhu ◽  
Weiyu Han ◽  
...  

Abstract Background:To describe demographic and clinical factors associated with the prevalence and incidence of depression and explore the temporal relationship between depression and joint symptoms in patients with symptomatic knee osteoarthritis (OA). Methods:413 participants were selected from a randomized controlled trial in people with symptomatic knee OA and vitamin D deficiency (age 63.2 ± 7.0 year, 50.4% female). Depression severity and knee joint symptoms were assessed using the patient health questionnaire (PHQ-9) and the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC), respectively, at baseline and 24 months. Results: The prevalence and incidence of depression was 25.4% and 11.2%, respectively. At baseline, having younger age, a higher body mass index (BMI), greater scores of WOMAC pain (PR: 1.05, 95%CI:1.03, 1.07), dysfunction (PR: 1.02, 95%CI:1.01, 1.02) and stiffness (PR: 1.05, 95%CI: 1.02, 1.09), lower education level, having more than one comorbidity and having two or more painful body sites were significantly associated with a higher prevalence of depression. Over 24 months, being female, having a higher WOMAC pain (RR: 1.05, 95%CI: 1.02, 1.09) and dysfunction score (RR: 1.02, 95%CI: 1.01, 1.03) at baseline and having two or more painful sites were significantly associated with a higher incidence of depression. In contrast, baseline depression was not associated with changes in knee joint symptoms over 24 months. Conclusion: Knee OA risk factors and joint symptoms, along with co-existing multi-site pain are associated with the prevalence and development of depression. This suggests that managing common OA risk factors and joint symptoms may be important for prevention and treatment depression in patients with knee OA.Trial registration: ClinicalTrials.gov identifier: NCT01176344Anzctr.org.au identifier: ACTRN12610000495022


2021 ◽  
Vol 22 (1) ◽  
Author(s):  
Shuang Zheng ◽  
Liudan Tu ◽  
Flavia Cicuttini ◽  
Zhaohua Zhu ◽  
Weiyu Han ◽  
...  

Abstract Background To describe demographic and clinical factors associated with the presence and incidence of depression and explore the temporal relationship between depression and joint symptoms in patients with symptomatic knee osteoarthritis (OA). Methods Three hundred ninety-seven participants were selected from a randomized controlled trial in people with symptomatic knee OA and vitamin D deficiency (age 63.3 ± 7.1 year, 48.6% female). Depression severity and knee joint symptoms were assessed using the patient health questionnaire (PHQ-9) and the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC), respectively, at baseline and 24 months. Results The presence and incidence of depression was 25.4 and 11.2%, respectively. At baseline, having younger age, a higher body mass index (BMI), greater scores of WOMAC pain (PR: 1.05, 95%CI:1.03, 1.07), dysfunction (PR: 1.02, 95%CI:1.01, 1.02) and stiffness (PR: 1.05, 95%CI: 1.02, 1.09), lower education level, having more than one comorbidity and having two or more painful body sites were significantly associated with a higher presence of depression. Over 24 months, being female, having a higher WOMAC pain (RR: 1.05, 95%CI: 1.02, 1.09) and dysfunction score (RR: 1.02, 95%CI: 1.01, 1.03) at baseline and having two or more painful sites were significantly associated with a higher incidence of depression. In contrast, baseline depression was not associated with changes in knee joint symptoms over 24 months. Conclusion Knee OA risk factors and joint symptoms, along with co-existing multi-site pain are associated with the presence and development of depression. This suggests that managing common OA risk factors and joint symptoms may be important for prevention and treatment depression in patients with knee OA. Trial registration ClinicalTrials.gov identifier: NCT01176344. Anzctr.org.au identifier: ACTRN12610000495022.


e-CliniC ◽  
2014 ◽  
Vol 2 (3) ◽  
Author(s):  
William Kusuma ◽  
Engeline Angliadi ◽  
L. S. Angliadi

Abstract: osteoarthritis is derived from greek meaning bone, arthro meaning joint and itis meaning inflammation. Osteoarthritis is a degenerative joint disease that is chronic,progessive runing slow, often inflamed or causes only mild inflammation, and characterized by deterioration and abrasion of articular cartilage as well as by two risk factor are: risk factors that cannot be changed and modifable risk factors. Obesity is a global epidemic in developed countries and developing countries such as Indonesia, particularly in urban strip. This situation is caused by unbalanced energy intake with energy expenditure and excess energy is stored as body fat within a specified period. Objectives: this study aimed to determine the role of risk factor of obesity on the incidence of osteoarthitis of the knee in patients who visit the Rehabilitation Medical Installation BLU Prof. DR. R. D. Kandou Manado. Method: this type of research is descriptive research by taking medical record in medical rehabillitation installation at BLU RSUP Prof. DR. R. D. Kandou Manado. Result: in this study was obtained from descriptive data/medical record(MR) found the number of patients diagnosed with osteoarthritis of the knee by 74 people. Obtained as many as 31 people who have data(weight and height),3 complete lack data because just have weight and 40 people don’t have either weight or height. Research results knee OA patient who come control in the installation of medical rehabillitation only 31are listed the data Body Mass Indeks(weight and height), there are 5 people who have normal BMI, and 26 people who had a BMI of both overweight and obesity excess. Conclusion: from here we may see one of the risk factor for OA knee is obesity Keywords: Knee osteoarthritis, obesity.     Abstrak: Osteoartritis (OA) berasal dari bahasa Yunani yaitu osteo yang berarti tulang, arthro yang berarti sendi dan itis yang berarti inflamasi. Osteoartritis adalah penyakit degeneratif sendi yang bersifat kronik,  berjalan progresif lambat, seringkali tidak meradang atau hanya menyebabkan inflamasi ringan, dan ditandai dengan adanya deteriorasi dan abrasi rawan sendi serta  oleh 2 faktor resiko yaitu: faktor resiko yang tidak dapat diubah dan faktor resiko yang dapat diubah. Obesitas merupakan epidemi global pada negara-negara maju dan negara berkembang seperti di Indonesia,  terutama di daerah perkotaan. Keadaan ini diakibatkan  karena pemasukan energi tidak seimbang dengan pengeluaran energi dan kelebihan energi ini disimpan dalam bentuk lemak tubuh dalam jangka waktu tertentu. Tujuan: Penelitian ini bertujuan untuk mengetahui peranan faktor resiko obesitas terhadap angka kejadian osteoartritis lutut pada penderita yang berkunjung di Instalasi Rehabilitasi Medik BLU RSUP Prof. DR. R. D. Kandou Manado. Metode: Jenis penelitian ini adalah penelitian deskriptif dengan mengambil data rekam medik di Instalasi Rehabilitasi Medik BLU RSUP Prof. DR. R. D. Kandou Manado.  Hasil: Pada penelitian yang didapatkan dari data deskriptif/rekam medik (RM) didapatkan jumlah penderita yang didiagnosis dengan osteoartritis lutut sebanyak 74 orang. Didapatkan sebanyak 31 orang yang memiliki data BB dan TB, 3 data kurang lengkap yaitu hanya terdapat data BB dan 40 data yang tidak mempunyai baik BB maupun TB. Hasil penelitian menyatakan penderita OA lutut yang datang kontrol di Instalasi Rehabilitasi Medik,hanya 31 yang tercantum data IMT (BB&TB),terdapat 5 orang yang memiliki IMT normal,dan 26 orang yang memiliki IMT berlebih baik overweight maupun obesitas. Simpulan: Dari sini kita bisa melihat salah satu faktor resiko OA lutut adalah obesitas. Kata Kunci: Osteoartritis lutut, Obesitas.


Author(s):  
S. A. Maksimov ◽  
N. V. Fedorova ◽  
G. V. Artamonova

Lack of physical activity (PA) is considered as one of the risk factors for a number of chronic non-communicable diseases. The sedentary lifestyle of a significant part of developed countries population, along with the insufficient effectiveness of traditional tools to stimulate the PA of the population, determine the interest of healthcare in optimizing urban space for increasing PA. In Russia, the number of studies in this area is extremely small, which determines the purpose of this review: presentation of the foreign results of the implementation of practical concepts and programs for optimizing urban space, as well as prospective studies that demonstrate the most evidence-based causal relationships of PA changes. Focus in prevention of diseases in Russia over the past decade, determines the scientific interest in risk factors, the features of its formation, and possible ways of implementation. In this regard, the results of such topics will be in demand by Russian health care, which will require the conduct of own Russian studies, taking into account foreign experience.


Author(s):  
Stefania Angela Di Fusco ◽  
Antonella Spinelli ◽  
Lorenzo Castello ◽  
Edoardo Mocini ◽  
Michele Massimo Gulizia ◽  
...  

Mandatory working from home is one of the consequences of the COVID-19 pandemic for a large number of workers. Transition to working from home may significantly impact lifestyle, psychosocial status, and the overall health of workers. This review summarizes available data about the effects of lockdown measures, particularly working from home, on cardiovascular risk factors including sedentary lifestyle, unhealthy diet pattern, psychological distress, smoking, alcohol misuse, and cardiometabolic parameters. Finally, we suggest countermeasures that can attenuate the negative health impact of working from home. Indeed, timely and tailored interventions implemented by companies in cooperation with the health care system could allow workers to benefit more from some of the advantages associated with working from home.


Author(s):  
Amjad Waheed Yousuf ◽  
Awhad Mueed Yousuf ◽  
Aasiy Ul Erum

Knee Osteoarthritis (OA) is a major cause of pain and disability worldwide. In majority of cases of knee OA the etiology remains unidentified, however, a number of systemic and local biomechanical factors have been associated with the increased risk of this disorder. These factors may determine the onset of knee OA and rapidity with which the disorder progresses. Occupation and sports participation are among the commonly implicated risk factors and have been studied in detail for their relationship with knee OA. An increased risk of knee OA has been observed in people who are involved in jobs requiring bending and kneeling of the knee joint. Likewise, persons who participate in sports involving excessive strain of the knee joint also carry a higher risk of development of this disorder in the later part of their life. In this review we present the data, obtained from original resources, determining the relationship between occupation and sports participation with the onset and progression of knee OA.


2021 ◽  
Vol 28 (Supplement_1) ◽  
Author(s):  
E Pomeshkina ◽  
E Bazdyrev

Abstract Funding Acknowledgements Type of funding sources: None. Introduction. Currently, the risk factors are known for many diseases, including cardiovascular diseases. A part of the risk factors are modifiable, and therefore depend on health behaviour of every person. Young student age is the time to build the habits for a healthy lifestyle. Purpose. To study the modifiable risk factors for cardiovascular disease such as sedentary lifestyle, unhealthy diet, alcohol abuse and smoking in young university students. Material and methods. The study included 136 university students (24 males and 112 females), median age was 20 (20; 21). The risk factors such as sedentary lifestyle, unhealthy diet, alcohol abuse and smoking were assessed using a questionnaire developed with the help of the adapted international methodologies.  Results. The research revealed that 91 (67 %) students have never smoked, 29 (21 %) quit smoking and 16 (12 %) are current smokers. The physical activity analysis showed that 58 (43 %) students have 150 or more minutes of walking activity a week (excluding a way to the study place). 47 (35 %) students have workouts 2-3 times a week and 9 (7 %) do it 5-7 times a week. 50 (37 %) students do not drink alcohol. Almost half of the students (66 (46 %) people) rarely drink alcohol (up to once a week), 10 (7 %) students drink alcohol 2-3 times a week; 10 (7 %) students drink alcohol often (4-6 times per week). The assessment of the eating habits showed that only 26 (19 %) students include vegetables and fruits into their regular diet (6-7 times a week). 78 (57 %) students eat vegetables and fruits rarely (up to 2 times a week). The rest of students (32 (24 %)) almost never eat vegetables and fruits (0-1 times a week). The bratwursts and sausages are included in the daily diet in 20 (14 %) students. 62 (46 %) students eat bratwursts and sausages very often (up to 3-5 times a week). A considerable part of the students (54 (40 %)) completely refuse or rarely eat these products. Most of the students (98 (72 %)) do not drink or drink rarely (1-2 times a week) sweet carbonated soft drinks. 6 (4 %) students often (up to 6-7 times a week) drink sweet carbonated soft drinks, the median daily consumption is 500 (250; 500) ml. 50 (37 %) students refuse to visit fast food restaurants. 40 (29 %) students visit them rarely (0-1 times a week). The rest of the students (46 (34 %)) visit fast food restaurants quite often (2-3 times a week). Conclusions. The research allows to conclude that the university students don"t have the habits for keeping a healthy lifestyle. The proportion of the students who smoke is 12 %, and the number of students who often drink alcohol (more than 3 times a week) is 14 %. More than half of the students (58 %) lead a sedentary lifestyle, most of the students (60 %) eat bratwursts and sausages daily or very often. 34 % of the students often visit fast-food restaurants. But a considerable part of the students (72 %) refuse to drink sweet carbonated beverages.


2020 ◽  
Author(s):  
Shuang Zheng ◽  
Liudan Tu ◽  
Flavia Cicuttini ◽  
Zhaohua Zhu ◽  
Weiyu Han ◽  
...  

Abstract Background To describe demographic and clinical factors associated with the prevalence and incidence of depression and explore the temporal relationship between depression and joint symptoms in patients with symptomatic knee osteoarthritis (OA). Methods 413 participants were selected from a randomized controlled trial in people with symptomatic knee OA and vitamin D deficiency (age 63.2 ± 7.0 year, 50.4% female). Depression severity and knee joint symptoms were assessed using the patient health questionnaire (PHQ-9) and the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC), respectively, at baseline and 24 months. Results The prevalence and incidence of depression was 25.4% and 11.2%, respectively. At baseline, having a higher body mass index (BMI), greater scores of WOMAC pain (PR: 1.05, 95%CI:1.03, 1.07), dysfunction (PR: 1.02, 95%CI:1.01, 1.02) and stiffness (PR: 1.05, 95%CI: 1.02, 1.09), lower education level, having more than one comorbidity and having two or more painful body sites were significantly associated with a higher prevalence of depression. Over 24 months, being female, having a higher WOMAC pain (RR: 1.04, 95%CI: 1.00, 1.08) and dysfunction score (RR: 1.01, 95%CI: 1.00, 1.02) at baseline and having two or more painful sites were significantly associated with a higher incidence of depression. In contrast, baseline depression was not associated with changes in knee joint symptoms over 24 months. Conclusion Knee OA risk factors and joint symptoms, along with co-existing multi-site pain are associated with the prevalence and development of depression. This suggests that managing common OA risk factors and joint symptoms could be important for prevention and treatment depression in patients with knee OA.


Author(s):  
Edy Irwanto ◽  
Dwi Pudjonarko ◽  
Hermina Sukmaningtyas

THE CORRELATION OF UNILATERAL LOW BACK PAIN INTENSITY AND THE DEGREE OF CONTRALATERAL KNEE OSTEOARTHRITISABSTRACTIntroduction: Low back pain (LBP) is one of the most common and recurring forms of musculoskeletal pain. In back injuries or disc degenerative diseases that cause chronic LBP will increase the burden on the knee joint, thereby triggering or exacerbating the occurrence of osteoarthritis (OA) of the knee.Aims: To analyze the correlation of unilateral LBP intensity and the degree of contralateral knee OA.Methods: Cross-sectional observational analytic study of LBP patients who went to the neurology polyclinic of RSUP Dr. Kariadi, Semarang, from November 2018 to March 2019. The diagnosis of knee OA was made clinically based on the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) questionnaire and radiological with Kellgren-Lawrence scores. Fisher’s exact test was used to see the correlation between variables, and the results of the bi- variate analysis was continued with a logistic regression multivariate test to find out the variables that influence the degree of knee OA.Results: There were 36 subjects, the majority of which were women (58.3%) with an average age of 53.88±11.01 years. A significant relationship was found between the unilateral LBP intensity (p=0.004; Odds ratio/OR=32,500) and malalignment of the knee joint (p=0.024;  OR=11.67) with the degree of contralateral  knee OA based on the WOMAC score.Discussion: The unilateral LBP intensity and malalignment of the knee joint can increase the risk of contralateral knee OA based on WOMAC scores of 32.5 and 11.7 times, respectively.Keywords: Kellgren-Lawrence score, low back pain, osteoarthritis of the knee, WOMAC scoreABSTRAKPendahuluan: Nyeri punggung bawah (NPB) adalah salah satu bentuk nyeri muskuloskeletal yang paling umum terjadi dan dapat berulang. Pada cedera punggung atau penyakit degeneratif diskus yang menyebabkan NBP kronik akan meningkatkan beban pada sendi lutut, sehingga memicu atau memperparah terjadinya osteoartritis (OA) lutut.Tujuan: Untuk mengetahui hubungan intensitas NPB unilateral dengan derajat OA lutut kontralateral.Metode: Penelitian analitik observasional secara potong lintang terhadap pasien NPB yang berobat ke Poliklinik Saraf RSUP Dr. Kariadi, Semarang, pada bulan November 2018 hingga Maret 2019. Diagnosis OA lutut ditegakkan ber- dasarkan klinis menggunakan kuesioner Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) dan radiologis dengan skor Kellgren-Lawrence. Korelasi antar variabel menggunakan uji Fisher’s exact, hasil analisis bivariat dilanjutkan dengan uji multivariat regresi logistik untuk mengetahui variabel yang berpengaruh terhadap derajat OA lutut.Hasil: Didapatkan 36 subjek yang mayoritas perempuan (58,3%) dengan rerata usia 53,88±11,01 tahun. Didapatkan hubungan yang bermakna antara intensitas NPB unilateral (p=0,004; rasio Odds/RO=32,500) dan malalignment sendi lutut (p=0,024; RO=11,67) dengan derajat OA lutut kontralateral berdasarkan skor WOMAC.Diskusi: Intensitas NPB unilateral dan malalignment sendi lutut dapat meningkatkan risiko terjadinya OA lutut kontralateral berdasarkan skor WOMAC masing-masing sebanyak 32,5 dan 11,7 kali.Kata kunci: Nyeri punggung bawah, osteoartritis lutut, skor WOMAC, skor Kellgren-Lawrence


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