PROFIL PENDERITA OSTEOARTRITIS LUTUT DENGAN OBESITAS DI INSTALASI REHABILITASI MEDIK BLU RSUP PROF. DR. R. D KANDOU MANADO

Abstract: osteoarthritis is derived from greek meaning bone, arthro meaning joint and itis meaning inflammation. Osteoarthritis is a degenerative joint disease that is chronic,progessive runing slow, often inflamed or causes only mild inflammation, and characterized by deterioration and abrasion of articular cartilage as well as by two risk factor are: risk factors that cannot be changed and modifable risk factors. Obesity is a global epidemic in developed countries and developing countries such as Indonesia, particularly in urban strip. This situation is caused by unbalanced energy intake with energy expenditure and excess energy is stored as body fat within a specified period. Objectives: this study aimed to determine the role of risk factor of obesity on the incidence of osteoarthitis of the knee in patients who visit the Rehabilitation Medical Installation BLU Prof. DR. R. D. Kandou Manado. Method: this type of research is descriptive research by taking medical record in medical rehabillitation installation at BLU RSUP Prof. DR. R. D. Kandou Manado. Result: in this study was obtained from descriptive data/medical record(MR) found the number of patients diagnosed with osteoarthritis of the knee by 74 people. Obtained as many as 31 people who have data(weight and height),3 complete lack data because just have weight and 40 people don’t have either weight or height. Research results knee OA patient who come control in the installation of medical rehabillitation only 31are listed the data Body Mass Indeks(weight and height), there are 5 people who have normal BMI, and 26 people who had a BMI of both overweight and obesity excess. Conclusion: from here we may see one of the risk factor for OA knee is obesity Keywords: Knee osteoarthritis, obesity. Abstrak: Osteoartritis (OA) berasal dari bahasa Yunani yaitu osteo yang berarti tulang, arthro yang berarti sendi dan itis yang berarti inflamasi. Osteoartritis adalah penyakit degeneratif sendi yang bersifat kronik, berjalan progresif lambat, seringkali tidak meradang atau hanya menyebabkan inflamasi ringan, dan ditandai dengan adanya deteriorasi dan abrasi rawan sendi serta oleh 2 faktor resiko yaitu: faktor resiko yang tidak dapat diubah dan faktor resiko yang dapat diubah. Obesitas merupakan epidemi global pada negara-negara maju dan negara berkembang seperti di Indonesia, terutama di daerah perkotaan. Keadaan ini diakibatkan karena pemasukan energi tidak seimbang dengan pengeluaran energi dan kelebihan energi ini disimpan dalam bentuk lemak tubuh dalam jangka waktu tertentu. Tujuan: Penelitian ini bertujuan untuk mengetahui peranan faktor resiko obesitas terhadap angka kejadian osteoartritis lutut pada penderita yang berkunjung di Instalasi Rehabilitasi Medik BLU RSUP Prof. DR. R. D. Kandou Manado. Metode: Jenis penelitian ini adalah penelitian deskriptif dengan mengambil data rekam medik di Instalasi Rehabilitasi Medik BLU RSUP Prof. DR. R. D. Kandou Manado. Hasil: Pada penelitian yang didapatkan dari data deskriptif/rekam medik (RM) didapatkan jumlah penderita yang didiagnosis dengan osteoartritis lutut sebanyak 74 orang. Didapatkan sebanyak 31 orang yang memiliki data BB dan TB, 3 data kurang lengkap yaitu hanya terdapat data BB dan 40 data yang tidak mempunyai baik BB maupun TB. Hasil penelitian menyatakan penderita OA lutut yang datang kontrol di Instalasi Rehabilitasi Medik,hanya 31 yang tercantum data IMT (BB&TB),terdapat 5 orang yang memiliki IMT normal,dan 26 orang yang memiliki IMT berlebih baik overweight maupun obesitas. Simpulan: Dari sini kita bisa melihat salah satu faktor resiko OA lutut adalah obesitas. Kata Kunci: Osteoartritis lutut, Obesitas.

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Cardiovascular risk factors during cancer treatment: prevalence, incidence and prognostic relevance

European Heart Journal ◽

10.1093/ehjci/ehaa946.3251 ◽

2020 ◽

Vol 41 (Supplement_2) ◽

Author(s):

J Caro Codon ◽

T Lopez-Fernandez ◽

C Alvarez-Ortega ◽

P Zamora Aunon ◽

I Rodriguez Rodriguez ◽

...

Keyword(s):

Risk Factors ◽

Risk Factor ◽

Cardiovascular Risk ◽

Cancer Therapy ◽

Cancer Patients ◽

Individual Risk ◽

Funding Source ◽

Number Of Patients ◽

All Cause Mortality

Abstract Background The actual usefulness of CV risk factor assessment in the prognostic evaluation of cancer patients treated with cardiotoxic treatment remains largely unknown. Design Prospective multicenter study in patients scheduled to receive anticancer therapy related with moderate/high cardiotoxic risk. Methods A total of 1324 patients underwent follow-up in a dedicated cardio-oncology clinic from April 2012 to October 2017. Special care was given to the identification and control of CV risk factors. Clinical data, blood samples and echocardiographic parameters were prospectively collected according to protocol, at baseline before cancer therapy and then at 3 weeks, 3 months, 6 months, 1 year, 1.5 years and 2 years after initiation of cancer therapy. Results At baseline, 893 patients (67.4%) presented at least 1 risk factor, with a significant number of patients newly diagnosed during follow-up. Individual risk factors were not related with worse prognosis during a 2-year follow-up. However, a higher Systemic Coronary Risk Estimation (SCORE) was significantly associated with higher rates of severe cardiotoxicity and all-cause mortality [HR 1.79 (95% CI 1.16–2.76) for SCORE 5–9 and HR 4.90 (95% CI 2.44–9.82) for SCORE ≥10 when compared with patients with lower SCORE (0–4)]. Conclusions This large cohort of patients treated with a potentially cardiotoxic regimen showed a significant prevalence of CV risk factors at baseline and significant incidence during follow-up. Baseline cardiovascular risk assessment using SCORE predicted severe cardiotoxicity and all-cause mortality. Therefore, its use should be recommended in the evaluation of cancer patients. Funding Acknowledgement Type of funding source: Public grant(s) – National budget only. Main funding source(s): This study was partially funded by the Fondo Investigaciones Sanitarias (Spain), Centro de Investigaciόn Biomédica en Red Cardiovascular CIBER-CV (Spain)

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Baseline risk factor prevalence among adolescents aged 15–17 years old: findings from National Non-communicable Disease Monitoring Survey (NNMS) of India

BMJ Open ◽

10.1136/bmjopen-2020-044066 ◽

2021 ◽

Vol 11 (6) ◽

pp. e044066

Author(s):

Prashant Mathur ◽

Vaitheeswaran Kulothungan ◽

Sravya Leburu ◽

Anand Krishnan ◽

Himanshu Kumar Chaturvedi ◽

...

Keyword(s):

Physical Activity ◽

Risk Factors ◽

Rural Areas ◽

Communicable Disease ◽

National Level ◽

Developed Countries ◽

Overweight And Obesity ◽

Baseline Risk ◽

Attitudes And Practices ◽

Non Communicable Disease

ObjectiveTo generate national estimates of key non-communicable disease (NCD) risk factors for adolescents (15–17 years) identified in the National NCD Monitoring Framework and, study the knowledge, attitudes and practices towards NCD risk behaviours among school-going adolescents.Design and settingA community-based, national, cross-sectional survey conducted during 2017–2018. The survey was coordinated by the Indian Council of Medical Research—National Centre for Disease Informatics and Research with 10 reputed implementing research institutes/organisations across India in urban and rural areas.ParticipantsA multistage sampling design was adopted covering ages between 15 and 69 years—adolescents (15–17 years) and adults (18–69 years). The sample included 12 000 households drawn from 600 primary sampling units. All available adolescents (15–17 years) from the selected households were included in the survey.Main outcome measuresKey NCD risk factors for adolescents (15–17 years)—current tobacco and alcohol use, dietary behaviours, insufficient physical activity, overweight and obesity.ResultsOverall, 1402 households and 1531 adolescents completed the survey. Prevalence of current daily use of tobacco was 3.1% (95% CI: 2.0% to 4.7%), 25.2% (95% CI: 22.2% to 28.5%) adolescents showed insufficient levels of physical activity, 6.2% (95% CI: 4.9% to 7.9%) were overweight and 1.8% (95% CI: 1.0% to 2.9%) were obese. Two-thirds reported being imparted health education on NCD risk factors in their schools/colleges.ConclusionThe survey provides baseline data on NCD-related key risk factors among 15–17 years in India. These national-level data fill information gaps for this age group and help assess India’s progress towards NCD targets set for 2025 comprehensively. Though the prevalence of select risk factors is much lower than in many developed countries, this study offers national evidence for revisiting and framing appropriate policies, strategies for prevention and control of NCDs in younger age groups.

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Etiology of ischemic stroke among young adults of Serbia

Vojnosanitetski pregled ◽

10.2298/vsp0811803j ◽

2008 ◽

Vol 65 (11) ◽

pp. 803-809 ◽

Cited By ~ 8

Author(s):

Dejana Jovanovic ◽

Ljiljana Beslac-Bumbasirevic ◽

Ranko Raicevic ◽

Jasna Zidverc-Trajkovic ◽

Marko Ercegovac

Keyword(s):

Risk Factors ◽

Young Adults ◽

Ischemic Stroke ◽

Heart Diseases ◽

Developed Countries ◽

Large Artery ◽

Stroke Treatment ◽

Prosthetic Valves ◽

Number Of Patients ◽

Coagulation Inhibitors

Background/Aim. Etiology of ischemic stroke (IS) among young adults varies among countries. The aim of the study was to investigate the causes and risk factors of IS in the young adults of Serbia. Methods. A total of 865 patients with IS, aged 15 to 45 years, were treated throughout the period 1989-2005. Etiologic diagnostic tests were performed on the patient by the patient basis and according to their availability at the time of investigation. The most likely cause of stroke was categorized according to the TOAST (Trial of ORG 10172 in Acute Stroke Treatment) criteria. Results. There were 486 men and 379 women, with 19% of the patients ? 30 years old. Large artery arteriosclerosis and small artery disease were confirmed in 14% of the patients, and embolism and other determined causes in 20%. Undetermined causes made up 32% of the patients, mostly those (26%) with incomplete investigations. Smoking (37%), hypertension (35%) and hyperlipidemia (35%) were the most common risk factors. Rheumatic heart diseases and prosthetic valves were the most common causes of IS. Arterial dissections and coagulation inhibitors deficiency were detected in a small number of patients. Conclusion. Etiology of IS among Serbian young adults shares characteristics of those in both western and less developed countries.

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Administration of Antithrombotic Treatment Was a Risk Factor for Intraperitoneal Hemorrhage in Patients Undergoing Percutaneous Interventions for Liver Diseases.

10.21203/rs.3.rs-150259/v1 ◽

2021 ◽

Author(s):

Akira Asai ◽

Keisuke Yokohama ◽

Hideko Ohama ◽

Yusuke Tsuchimoto ◽

Shinya Fukunishi ◽

...

Keyword(s):

Risk Factors ◽

Risk Factor ◽

Liver Diseases ◽

Retrospective Cohort ◽

Clinical Characteristics ◽

Ultrasound Guided ◽

Antithrombotic Treatment ◽

Percutaneous Interventions ◽

Intraperitoneal Hemorrhage ◽

Number Of Patients

Abstract Percutaneous interventions for liver diseases are currently essential for diagnosis and treatment. The most frequent complication of percutaneous interventions is intraperitoneal hemorrhage. Recently, the number of patients with liver diseases and administered antithrombotics has been increasing. This retrospective cohort study aimed to evaluate the risk factors for intraperitoneal hemorrhage after percutaneous interventions for liver diseases. This study recruited 1025 patients who underwent percutaneous interventions for liver diseases from April 2015 to March 2020. All interventions were performed using an ultrasound-guided approach. Intraperitoneal hemorrhage after percutaneous interventions was detected by abdominal computed tomography. Intraperitoneal hemorrhage occurred in 9 patients (0.88%), and these adverse events weren’t severe. We compared clinical characteristics between the patients with intraperitoneal hemorrhage and without. There were differences regarding patients who underwent percutaneous treatments of liver tumor (p = 0.1271), administration of antithrombotics (p = 0.1961), and prothrombin time (p = 0.1683). Thereafter, to evaluate the influence of antithrombotics on hemorrhage, we compared the patients with antithrombotics and without. After propensity score matching, hemorrhage in patients treated with antithrombotics was significantly increased than in those without (p = 0.0407). The administration of antithrombotics was a risk factor for intraperitoneal hemorrhage in patients undergoing percutaneous interventions for liver diseases.

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A Perspective on Robotic Assistance for Knee Arthroplasty

Advances in Orthopedics ◽

10.1155/2013/970703 ◽

2013 ◽

Vol 2013 ◽

pp. 1-9 ◽

Cited By ~ 29

Author(s):

Nathan A. Netravali ◽

Feimo Shen ◽

Youngbae Park ◽

William L. Bargar

Keyword(s):

Surgical Technique ◽

Knee Arthroplasty ◽

Clinical Results ◽

Degenerative Joint Disease ◽

Joint Disease ◽

Implant Design ◽

Robotic Assistance ◽

Surgical Assistance ◽

Number Of Patients ◽

Assistance Systems

Knee arthroplasty is used to treat patients with degenerative joint disease of the knee to reduce pain and restore the function of the joint. Although patient outcomes are generally quite good, there are still a number of patients that are dissatisfied with their procedures. Aside from implant design which has largely become standard, surgical technique is one of the main factors that determine clinical results. Therefore, a lot of effort has gone into improving surgical technique including the use of computer-aided surgery. The latest generation of orthopedic surgical tools involves the use of robotics to enhance the surgeons’ abilities to install implants more precisely and consistently. This review presents an evolution of robot-assisted surgical systems for knee replacement with an emphasis on the clinical results available in the literature. Ever since various robotic-assistance systems were developed and used clinically worldwide, studies have demonstrated that these systems are as safe as and more accurate than conventional methods of manual implantation. Robotic surgical assistance will likely result in improved surgical technique and improved clinical results.

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Risk Factors Associated With Sino-Nasal Polyposis And Its Relationship With The Occupational Inhalants

Journal of Bahria University Medical and Dental College ◽

10.51985/jbumdc2018091 ◽

2019 ◽

Vol 09 (04) ◽

pp. 290-293

Author(s):

Qaisar Sajad ◽

Ayub Musani ◽

Faheem Ahmed Khan

Keyword(s):

Risk Factors ◽

Risk Factor ◽

Nasal Polyposis ◽

Local Population ◽

Tertiary Care ◽

Nasal Allergy ◽

Care Hospital ◽

Common Risk Factor ◽

Factors Associated ◽

Number Of Patients

Objective: To determine the risk factors associated with sino-nasal polyposis and its relationship with the exposure of occupational inhalants in patients presenting in a tertiary care hospital of Karachi. Study design and Settings: Cross-sectional study conducted at department of otorhino-laryngology Karachi Medical & Dental College and Abbasi Shaheed Hospital Karachi for a period of two and a half years from October 2015 to April 2018. Methodology: Total number of patients included for this study were 221 patients with diagnosis of bilateral and multiple nasal polyposis with age greater than 10 years. Specifically, designed proforma was used for data collection specially in relation with occupation and exposure to different occupational inhalants and entered in SPSS version 23 for analysis. Results: There were 133 male and 88 female patient with a mean age was 36.16 ± 12.33 years. Mostly patients belonged to poor socio-economic status i.e. 133 (60.70%). Allergic rhinitis or nasal allergy was the most common risk factor present in 114 patients (51.6%) while aspirin hypersensitivity was the least common risk factor present in only 19 patients (8.5%). Most of the patients (76 or 34.4%) were related with one or the other form of agriculture and were exposed to different occupational inhalants like mud, pollens, animals and plants. Conclusions: Nasal allergy is the most common risk factor and occupational inhalant specially related with agriculture, poultry and pets are the common agents responsible for nasal polyposis in our local population.

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Risk Factor Related to Mortality of Diabetic Ketoacidosis Patients in Dr. Soetomo General Hospital Surabaya

JUXTA: Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga ◽

10.20473/juxta.v11i12020.36-40 ◽

2020 ◽

Vol 11 (1) ◽

pp. 36

Author(s):

Alviano Satria Wibawa ◽

Hermina Novida ◽

Muhammad Faizi ◽

Deasy Ardiany

Keyword(s):

Risk Factors ◽

Risk Factor ◽

Diabetic Ketoacidosis ◽

General Hospital ◽

Developed Countries ◽

Chi Square ◽

High Blood Glucose ◽

Electrolyte Disturbances ◽

Chi Square Test ◽

History Of

Introduction: Diabetic ketoacidosis (DKA) is a complication of diabetes mellitus which has a high risk of mortality. Mortality in DKA patients in developed countries is less than 5%, some other sources mention 5-10%, 2-10%, or 9-10%. Mortality events at clinics with simple facilities and elderly patients can reach 25-50%. The mortality rate of DKA patients is generally higher in infection conditions, especially in developing countries and in septic patients. Several factors such as age, sex, and high blood glucose can increase mortality risk of DKA patients. Other risk factors such as history of discontinued insulin therapy, impaired bicarbonate levels, pH, and increased leukocytes of DKA patients due to infection, abnormal albumin levels, electrolyte disturbances, and Serum Creatinine (SK) were thought to affect mortality of DKA patients. The purpose of this study was to determine the risk factors associated with mortality of DKA patients in Dr. Soetomo General Hospital Surabaya. Methods: The method used in this study was observational analytic involving 63 adult patients diagnosed with DKA with analysis using Chi-Square test. Results: From 63 patients included in this study, 37 patients diagnosed with DKA died and 26 patients lived. In a multivariate analysis, DKA severity with p = 0.001 (p < 0.005) was identified as having a relationship with mortality of DKA patients Dr. Soetomo General Hospital Surabaya. Conclusion: Severity is the only risk factor associated with mortality of DKA patients in Dr. Soetomo General Hospital Surabaya.

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Prevalence, risk factors and attitude of parents towards childhood obesity among school children in Bangalore city

International Journal of Community Medicine and Public Health ◽

10.18203/2394-6040.ijcmph20180262 ◽

2018 ◽

Vol 5 (2) ◽

pp. 749 ◽

Cited By ~ 2

Author(s):

Hemavathi Dasappa ◽

Farah Naaz Fathima ◽

Krithika Ganesh ◽

Shankar Prasad

Keyword(s):

Physical Activity ◽

Risk Factors ◽

Risk Factor ◽

School Children ◽

Private School ◽

Overweight And Obesity ◽

Parental Attitude ◽

Obesity And Overweight ◽

Potential Risk Factors ◽

Structured Questionnaire

Background: Aim of the study was to determine the prevalence, risk factor attitude of parents towards obesity and overweight among the school children between the age group of 6-13 years.Methods: A structured questionnaire was filled by the parents and weight and height was measured by school nurse in a private school in Bangalore city.Results: Prevalence of overweight was 13.20% and obesity was 17.13%. Birth weight and sport was strongly associated with the prevalence. Sports protect the child from the overweight and obesity. Parent’s perception about their child’s BMI status was good. Parent’s attitude of having meal with their child and their estimation of child’s physical activity was protective and the attitude of controlling diet of the child was a risk factor for overweight and obesity. Though the parents were able to estimate their child as overweight and obese they were not willing for further advice.Conclusions: Prevalence of overweight and obesity is increasing. Higher birth weights, parental attitude of controlling child’s diet are the potential risk factors. Involvement in sports, parental attitude of having food with child and awareness about their physical activity are protective.

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Ischemic Stroke and its Association with Risk Factors at Nepalgunj Medical College Teaching Hospital Kohalpur

Journal of Nepalgunj Medical College ◽

10.3126/jngmc.v18i2.38897 ◽

2021 ◽

Vol 18 (2) ◽

pp. 48-50

Author(s):

Shyam Kumar BK ◽

Sushil Baral ◽

Nabin Paudel ◽

Hitesh Neupane

Keyword(s):

Risk Factors ◽

Risk Factor ◽

Ischemic Stroke ◽

Carotid Artery ◽

College Teaching ◽

Intima Media Thickness ◽

Cerebrovascular Diseases ◽

Media Thickness ◽

Number Of Patients ◽

Carotid Doppler

Introduction: Incidence of stroke increases with age and growing elderly population worldwide, the number of patients with stroke are likely to increase. It is the third most common cause of death in world in that 85% are ischemic in nature. Atherosclerosis is a major risk factor in cerebrovascular diseases. Carotid Intima Media thickness (CIMT) is a surrogate marker of atherosclerosis and provides a non-invasive method for the risk assessment of cerebrovascular diseases. Aims: To study the atherosclerotic risk profile of patients admitted with ischemic stroke in medical ward with study of the carotid artery intima-media thickness in patients with acute ischemic stroke. Methods: 92 patients with ischemic strokes were studied in this observational study. Carotid Doppler was performed in all patients with emphasis on carotid artery stenosis and intima thickening. Analysis of Association of various risk factors was done in detail. Study period was from June 2019 to May 2020. Results: Higher degree of stenosis was associated with hypoechoic plaques and cortical strokes. Hypertension was the most common and most significant risk factor. Multiple risk factors also appear to have synergistic actions. Conclusion: Various modifiable risk factors provide valuable target for primary and secondary prevention of stroke. Carotid Doppler is a very cheap and highly effective tool for further management of stroke patients. Most of the asymptomatic patients, risk factors may warrant precautionary carotid Doppler, and may result in significant reduction in disease burden on the families and the community and should be encouraged.

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Association of osteoporosis and varus inclination of the tibial plateau in postmenopausal women with advanced osteoarthritis of the knee

BMC Musculoskeletal Disorders ◽

10.1186/s12891-021-04090-2 ◽

2021 ◽

Vol 22 (1) ◽

Author(s):

Shun-Ping Wang ◽

Po-Kuan Wu ◽

Cheng-Hung Lee ◽

Cheng-Min Shih ◽

Yung-Cheng Chiu ◽

...

Keyword(s):

Risk Factors ◽

Risk Factor ◽

Lower Extremity ◽

Postmenopausal Women ◽

Tibial Plateau ◽

Osteoarthritis Of The Knee ◽

Varus Malalignment ◽

Mineral Density ◽

T Score ◽

Lower Extremity Alignment

Abstract Background Although varus inclination of the tibial plateau has increasingly been recognized as a major risk factor in the progression of Osteoarthritis of the knee (OA knee), little attention has been placed on the development of the varus inclination of the tibial plateau. Osteoporosis is a disease characterized by low bone mass and may increase the risk of a stress fracture in the proximal tibia. To date, risk factors for varus inclination of the tibial plateau are rarely reported. In this study, we investigated Bone Mineral Density (BMD) as a risk factor of varus inclination of the tibial plateau in postmenopausal women with advanced OA knee. Methods A total of 90 postmenopausal women with varus OA knee who had received a total knee arthroplasty in our department between January 2016 and December 2019 were reviewed. Certain factors may correlate to inclination of the tibial plateau (Medial Tibial Plateau Angle, MTPA), including age, operation side, Kellgren-Lawrence grade of OA knee, BMD, Body Mass Index (BMI), Lateral Distal Femur Angle (LDFA), lower extremity alignment (Hip-Knee-Ankle angle, HKAA), and history of both spinal compression fracture and hip fracture were collected and analyzed. Results Osteoporosis, lower extremity varus malalignment and age were significantly associated with varus inclination of the tibial plateau (MTPA) (P = 0.15, 0.013 and 0.033 respectively). For patients with a lower extremity varus malalignment (HKAA < 175°), osteoporosis (T-score ≤ -2.5) was significantly associated with inclination of the tibial plateau. For patients with a normal lower extremity alignment (HKAA ≥ 175°), no significant association was found between osteoporosis (T-score ≤ -2.5) and varus inclination of the tibial plateau. Conclusions Osteoporosis, lower extremity varus malalignment and age are major risk factors for inclination of the tibial plateau in postmenopausal women with OA knee. More attention needs to be given to the progression of varus OA knee in postmenopausal women who simultaneously has osteoporosis and lower extremity varus malalignment.

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