scholarly journals Exploration of the Characteristics of Animal Supply and Demand in University Experimental Teaching Pratice

2021 ◽  
Vol 5 (1) ◽  
Author(s):  
Yongshi Cao
Keyword(s):  
Supply And Demand ◽  
Colleges And Universities ◽  
Laboratory Animals ◽  
Demand Characteristics ◽  
Experimental Animals ◽  
Vital Importance ◽  
Teaching Objectives ◽  
Experimental Teaching ◽  
Teaching Tasks

The supply and demand of laboratory animals for teaching in colleges and universities has its own internal characteristics. To grasp the supply and demand characteristics of laboratory animals for teaching is of vital importance to the planning, supply and use of teaching animals, the realization of teaching objectives and the completion of teaching tasks. Based on the supply of teaching experimental animals and the work of animal experimental teaching in our university in recent years, this paper expounds the inherent characteristics and practice of supply and demand of teaching experimental animals.

Features of the sensitivity of the central nervous system of the organism of experimental animals to the effects of certain psychotropic drugs and their combinations against the background of chronic alcohol intoxication in a chronopharmacological experiment

2020 ◽  
pp. 56-62
Author(s):  
E.V. Filippova
Keyword(s):  
Alcohol Intoxication ◽  
Laboratory Animals ◽  
Histological Structure ◽  
Chronic Alcohol ◽  
Behavioral Reactions ◽  
Experimental Animals ◽  
Chronic Alcohol Intoxication ◽  
Psychotropic Action ◽  
Adaptive Effect ◽  
The Central Nervous System

In a chronopharmacological experiment, the effect of two drugs with psychotropic action in combinations on the behavior of laboratory animals subjected to chronic alcohol intoxication was examined. Against the background of a deprimating agent, a decrease in the threshold of sensitivity to electrical irritation and the duration of an aggressive reaction was revealed; an increase in these indicators was established with a combination of a deprimating drug with an antioxidant. It has been shown that the antioxidant has a desynchronizing effect on the behavioral reactions of laboratory animals for two days, which indicates a pronounced adaptive effect. In the case of using combinations of a deprimating agent with an antioxidant, a decrease in the destruction of the histological structure of the myocardium against the background of chronic alcoholization was established.

Application of Research-Oriented Experimental Teaching in Biopharmaceutical Courses

2014 ◽  
Vol 672-674 ◽  
pp. 2237-2240
Author(s):  
Li Ping An ◽  
Guang Yu Xu ◽  
Xiao Han ◽  
Pei Ge Du ◽  
Huan Qi Wang
Keyword(s):  
Research Capacity ◽  
Teaching Model ◽  
Teaching Program ◽  
Experimental Examination ◽  
Teaching Objectives ◽  
Experimental Teaching ◽  
Research Activities ◽  
Teaching Content ◽  
Research Platform ◽  
Operational Ability

In this study, teaching contents and methods of bioharmaceuticals were improved, and a research-oriented teaching model was established. The teaching program was divided into three levels depending on the purpose of teaching and the teaching content of biopharmaceuticals was divided into three categories based on the level teaching objectives. Some visual and vivid multimedia coursewares were applied, the students were encouraged to participate in research activities, the writing of experimental reports was standardized, and the assessment of experimental examination was strengthened. The results showed that the reform of biopharmaceutical experiment teaching contents and method, the standardization of report writing and the improvement of experimental assessment should be helpful to stimulate the enthusiasm of students' autonomous learning, train the operational ability of students, cultivate their research thinking and provide an open and innovative research platform for the students. This may help students become biopharmaceutical research talents with a solid professional foundation, high overall quality and strong research capacity.

scholarly journals INVESTIGATED DYNAMICS OF ELIMINATION MAGNETITE NANOPARTICLES OF INHALED IN GUINEA PIGS

2014 ◽  
Vol 13 (1) ◽  
pp. 62-66
Author(s):  
A. V. Nosarev ◽  
Ye. Ye. Abramenko ◽  
L. V. Kapilevich ◽  
Ye. Yu. D’yakova ◽  
V. S. Selivanova
Keyword(s):  
Inflammatory Reaction ◽  
Magnetite Nanoparticles ◽  
Guinea Pigs ◽  
Laboratory Animals ◽  
Histological Changes ◽  
Experimental Animals ◽  
Long Course ◽  
Inhaled Nanoparticles

The article presents the results of a study of the dynamics of histological changes in the guinea pigs respiratory tissues due the process of elimination after a long course of inhaled nanoparticles of magnetite. In the experimental animals lungs as a result of prolonged inhalation nanomagnetite developed an inflammatory reaction, the accumulation of Perls -positive cells. These changes were not even a month later, when the input of magnetite nanoparticles in laboratory animals.

scholarly journals The Improvement Strategy of Inorganic Chemistry Experiment Teaching Method in Colleges and Universities

2020 ◽  
Vol 4 (9) ◽  
Author(s):  
Danfeng He ◽  
Fujiang Zhou ◽  
Jinjun Deng ◽  
Cheng Chen ◽  
Chao Liu ◽  
...  
Keyword(s):  
Inorganic Chemistry ◽  
Teaching Methods ◽  
Teaching Method ◽  
Colleges And Universities ◽  
Traditional Teaching ◽  
Improvement Strategy ◽  
Teaching System ◽  
Teaching Reform ◽  
Experimental Teaching ◽  
Chemistry Experiment

As one of the teaching methods of chemistry in colleges and universities, experimental teaching is the inevitable path of teaching development that is obviously different from traditional teaching, and it is also an indispensable part of constructing and perfecting teaching system and implementing teaching reform. In this case, this paper analyzes and explores in detail the problems existing in inorganic chemistry experiment teaching in colleges and universities, and puts forward relevant methods and measures to provide some valuable references for the optimization of inorganic chemistry experiment methods.

scholarly journals THE IMMUNOMODELING ACTIVITY OF BISMUTH CITRATE IN EXPERIMENT 1-CSTL AND LABORATORY OF INDUSTRIAL TOXICOLOGY

2019 ◽  
Vol 4 (9-10) ◽  
pp. 134-139
Author(s):  
О. I. Hrushka ◽  
V. A. Turkina ◽  
B. P. Kuzminov
Keyword(s):  
Immune System ◽  
The Body ◽  
Skin Tests ◽  
Laboratory Animals ◽  
Experimental Conditions ◽  
Experimental Animals ◽  
Bismuth Citrate ◽  
Degree Of Sensitization ◽  
Sensitizing Effect

The aim of the study. To investigate in experimental conditions the effect of bismuth citrate on the immune system of laboratory animals. Material and methods. One-time sensitization of tadpoles (subcutaneously into the ear) was performed according to the method of O.G. Alekseeva, A.I. Petkevich. The degree of sensitization was established after skin tests. Determined the leucocyte blood formula, T and B lymphocytes in peripheral blood by the rosette method, immunoglobulins of class A, M, G in serum - by the method of radial immunodiffusion of globulines in agar Difco, circulating and extracellular complexes detection of the response of blood cells to the allergen "in vitro" - by the reaction of specific leukocyte lysis. Results. Bismuth citrate causes impaired immunological homeostasis in experimental animals. Indicators of nonspecific cellular component of the immune system have changed significantly, characterizing immunocomplex pathology. A decrease in the T-helper subpopulation was observed, indicating a significant immunomodulatory ability of bismuth citrate. At the same time, there was a significant increase in cells capable of rosette formation, which suggests that bismuth citrate is capable of provoking sensitization of the body. In the humoral immunity link, significant differences in the content of circulating immune complexes in sensitized and control animals were observed. Immunoglobulin levels were unchanged relative to control. The analysis of the sensitizing effect indicates that the most probable result of sensitization of the organism in this mode of receipt of bismuth citrate is the formation of type III hypersensitivity. Conclusions. Bismuth citrate under experimental conditions causes changes in the immune system of experimental animals, which are characteristic of the allergenic response of the organism to the complement-dependent type.

scholarly journals THE INFLUENCE OF OZONE THERAPY ON THE MORPHOLOGIC CHANGES IN THE PATIENTS PRESENTING WITH PURULENT INFLAMMATION OF THE LUNGS IN THE EXPERIMENT

2017 ◽  
Vol 16 (3) ◽  
pp. 137-140
Author(s):  
Gulora A. Sadykova ◽  
Kh. U Rakhmatullaev ◽  
R. Sh Mavlyan-Khodjaev ◽  
Z. S Zalyalova ◽  
Yu. Kh Tadjikhodjaeva
Keyword(s):  
Respiratory Tract ◽  
Chronic Inflammation ◽  
Saline Solution ◽  
Negative Impact ◽  
Morphological Changes ◽  
Laboratory Animals ◽  
Control Group ◽  
Experimental Animals ◽  
Mechanical Irritation ◽  
Inflammation Of The Lungs

We have created the experimental model of chronic inflammation of lungs by means of prolonged mechanical irritation of the bronchi in 30 outbred rats and studied the morphological changes in the lung tissue of these animals rats in three series of experiments. Each rat was given an intraperitoneal injection of an ozonised saline solution produced by a «Binafsha» ozonator. The objective of the study was to compare a control group of healthy animals and the group of experimental animals with chronic purulent pneumonia. The prolonged irritation of the respiratory tract in experimental animals was found to induce the structural changes in the tissues of the lungs characteristic of chronic purulent inflammation. The course of treatment with the ozonised saline solution in healthy animals with experimentally modelled chronic purulent inflammation of the lungs did not have a negative impact on the general condition and the behaviour of the animals. The treatment of experimental chronic inflammation of lungs caused by prolonged mechanical irritation of the respiratory tract resulted in the improvement of the morphological status of the laboratory animals, but the purulent inflammation process failed to be completely resolved after the treatment which needs to be taken into consideration in the clinical practice.

scholarly journals Bovine Herpesvirus Types 5 (BoHV5): A New and Emerging Threat in Indian Cattle

2021 ◽  
Author(s):  
K.D. Rawat ◽  
K.K. Chaubey
Keyword(s):  
Sexually Transmitted Diseases ◽  
Bovine Herpesvirus ◽  
Laboratory Animals ◽  
Test Protocol ◽  
Experimental Animals ◽  
Sexually Transmitted ◽  
The Central Nervous System ◽  
Indian Cattle ◽  
Subtype A ◽  
First Time

Bovine herpesvirus 5 (BoHV-5) belongs to the genus varicellovirus family herpesviridae and is a causative agent of meningo-encephalitis in cattle. BoHV-5 can replicates in the central nervous system (CNS) to cause encephalitis and establishes latency in the trigeminal ganglion of either naturally infected cattle or experimentally inoculated laboratory animals. BoHV 5 was first time reported in Australia in 1962 and subsequently reported in Latin Ameican countries Argentina, Brazil and Uruguay. Few cases of BoHV5 infection has also been reported in USA and Europe. Recently, the BoHV5 infection was reported in Indian cattle for the first time. The BoHV5 was isolated from aborted cattle and characterized as BoHV5 subtype A and this finding may necessitate inclusion of BoHV5 test protocol in testing of semen for sexually transmitted diseases. Because BoHV5 infection in cattle recently reported in India so, it is needed to explore the similarity of the isolates with earlier reported isolates and to check it’s pathogenicity to cause encephalitis in natural host and in experimental animals like rabbits, rat, guniea pig etc. Beside this, we have to explore the information about co-infection of BoHV5 with other viral, bacterial, fungal as well as parasitic agents.

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