scholarly journals Decreased Cognitive Function in People with Type 2 Diabetes Mellitus

2021 ◽  
Vol 16 (1) ◽  
pp. 34
Author(s):  
Shinta Kaozar Wiratman ◽  
Widya Hary Cahyati
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Cognitive Function ◽  
Blood Sugar ◽  
Cross Sectional ◽  
People With Dementia ◽  
Increased Risk ◽  
Risk Of Cancer

ABSTRACTBackground: The number of cases and the prevalence of diabetes has continued to increase over the past few decades. DM itself is associated with an increased risk of cancer, kidney failure, stroke, and decreased cognitive function that leads to dementia. In 2016 Indonesia has an estimated 1.2 million people with dementia and is expected to grow to 4 million by 2050.Objective: The purpose of this study was to find out the risk factors for decreased cognitive function in people with type 2 diabetes mellitus.Method: This type of research is observational analytics with cross sectional design. The sample was 62 respondents with purposive sampling techniques. The instrument used in the study was a structured questionnaire. Measurement of cognitive function using MoCA-INA questionnaire. Data collection is done by interview method to respondents.Result: The results showed that there was a relationship between the age of the respondent (PR= 2.98; 95% CI= 0.97-9.17), and the respondent's blood sugar level (PR= 3.31; 95% CI= 1.12-9.74) to decreased cognitive function in people with type 2 diabetes mellitus.Conclusion: Age and blood sugar levels of respondents contributed to decreased cognitive function of people with type 2 diabetes mellitus.

scholarly journals Relationship between Type 2 Diabetes Mellitus and Alcohol Consumption among Young Adults in Mangalore: A Cross Sectional Study

2021 ◽  
Vol 6 (3) ◽  
pp. 193-196
Author(s):  
Tobin Joseph ◽  
Saumya P Jose
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Young Adults ◽  
Alcohol Consumption ◽  
Blood Sugar ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional

Diabetes mellitus is one of the most common comorbid illnesses seen in adults and elderly individual. Its prevalence rate is increasing globally and in India. 7.1 % of the total population is affected with diabetes. The present study is a community based cross sectional study to investigate the relationship between alcohol consumption and diabetes incidence among young adults. 120 participants were recruited through purposive sampling. Fasting blood sugar and post prandial blood sugar level were taken to identify the diabetic profile. The data were collected and analyzed by using descriptive statistics and results showed that there is a strong association exit between these parameters. Keywords: Type 2 Diabetes Mellitus, Alcohol Consumption, Young Adult, Mangalore

scholarly journals Is the number of fast-food outlets in the neighbourhood related to screen-detected type 2 diabetes mellitus and associated risk factors?

2014 ◽  
Vol 18 (9) ◽  
pp. 1698-1705 ◽  
Author(s):  
Danielle H Bodicoat ◽  
Patrice Carter ◽  
Alexis Comber ◽  
Charlotte Edwardson ◽  
Laura J Gray ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Risk Factors ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Fast Food ◽  
Social Deprivation ◽  
Cross Sectional ◽  
Food Outlets ◽  
Increased Risk

AbstractObjectiveWe investigated whether a higher number of fast-food outlets in an individual’s home neighbourhood is associated with increased prevalence of type 2 diabetes mellitus and related risk factors, including obesity.DesignCross-sectional study.SettingThree UK-based diabetes screening studies (one general population, two high-risk populations) conducted between 2004 and 2011. The primary outcome was screen-detected type 2 diabetes. Secondary outcomes were risk factors for type 2 diabetes.SubjectsIn total 10 461 participants (mean age 59 years; 53 % male; 21 % non-White ethnicity).ResultsThere was a higher number of neighbourhood (500 m radius from home postcode) fast-food outlets among non-White ethnic groups (P<0·001) and in socially deprived areas (P<0·001). After adjustment (social deprivation, urban/rural, ethnicity, age, sex), more fast-food outlets was associated with significantly increased odds for diabetes (OR=1·02; 95 % CI 1·00, 1·04) and obesity (OR=1·02; 95 % CI 1·00, 1·03). This suggests that for every additional two outlets per neighbourhood, we would expect one additional diabetes case, assuming a causal relationship between the fast-food outlets and diabetes.ConclusionsThese results suggest that increased exposure to fast-food outlets is associated with increased risk of type 2 diabetes and obesity, which has implications for diabetes prevention at a public health level and for those granting planning permission to new fast-food outlets.

scholarly journals Noncommunicable disease among adults with cerebral palsy

Neurology ◽  
2019 ◽  
Vol 93 (14) ◽  
pp. e1385-e1396 ◽  
Author(s):  
Jennifer M. Ryan ◽  
Mark D. Peterson ◽  
Anthony Matthews ◽  
Nicola Ryan ◽  
Kimberley J. Smith ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Cardiovascular Disease ◽  
Type 2 Diabetes Mellitus ◽  
Cerebral Palsy ◽  
Respiratory Disease ◽  
Noncommunicable Disease ◽  
Increased Risk ◽  
Risk Of Cancer

ObjectiveTo compare the incidence of noncommunicable diseases between adults with and without cerebral palsy (CP).MethodsA cohort study was conducted using primary care data from the Clinical Practice Research Datalink. Cox models, stratified by matched set and adjusted for potential confounders, were fitted to compare the risk of any noncommunicable disease, cancer, cardiovascular disease, type 2 diabetes mellitus, and respiratory disease between adults with and without CP.ResultsThe analysis included 1,705 adults with CP and 5,115 age-, sex-, and general practice–matched adults without CP. There was evidence from adjusted analyses that adults with CP had 75% increased risk of developing any noncommunicable disease compared to adults without CP (hazard ratio [HR] 1.75, 95% confidence interval [CI] 1.58–1.94). Specifically, they had increased risk of cardiovascular disease (HR 1.76, 95% CI 1.48–2.11) and respiratory disease (HR 2.61, 95% CI 2.14–3.19). There was no evidence of increased risk of cancer or type 2 diabetes mellitus.ConclusionsAdults with CP had increased risk of noncommunicable disease, specifically cardiovascular and respiratory disease. These findings highlight the need for clinical vigilance regarding identification of noncommunicable disease in people with CP and further research into the etiology and management of noncommunicable disease in this population.

scholarly journals TYPE 2 DIABETES MELLITUS;

2013 ◽  
Vol 20 (05) ◽  
pp. 804-809
Author(s):  
RAHEEL IFTIKHAR ◽  
SULTAN MEHMOOD KAMRAN ◽  
KUMAIL ABBASS, ◽  
Ehtesham Haider,
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Serum Magnesium ◽  
Armed Forces ◽  
Military Hospital ◽  
Cross Sectional ◽  
Number Of Patients ◽  
Increased Risk

Objective: To determine frequency of Hypomagnesaemia in patients of type 2 diabetes mellitus in our population. DataSource: Random selection of DM II patients from Outpatient Department CMH, Kharian. Design: Cross sectional study. Setting:Combined Military Hospital Kharian, Department of Medicine. Duration of study: January 2011 to December 2011. Materials &Methods: We selected outdoor patients of DM-2 from both gender between 40 to 70 yrs of age by random sampling. Those selected,were subjected to blood fasting and random glucose measurements as well as serum magnesium levels. Blood samples were collectedusing full aseptic measures and within one hour, samples were transported to Armed Forces institute of Pathology (AFIP) for analysis.Serum magnesium level estimation was done by timed endpoint method using calmagite dye. DXC 600 automated analyzer was used.The results were verified by Pathologist. Results: The overall frequency of Hypomagnesemia was 32.2% (124 out of the 385 subjects)using the cutoff value of less than 0.6mmol/l for Hypomagnesaemia, whereas 67.8% (261 out of the 385 individual) had normal serummagnesium levels. Conclusions: Significant number of patients with type 2 diabetes mellitus suffers from Hypomagnesaemia. Thesepatients have increased risk risk of poor Glycemic control and diabetic complications due to Hypomagnesemia. Therefore, it isrecommended that serum magnesium levels should be checked regularly in patients with type 2 diabetes mellitus and oral magnesiumreplacement should be done.

scholarly journals DPP4i, thiazolidinediones, or insulin and risks of cancer in patients with type 2 diabetes mellitus on metformin–sulfonylurea dual therapy with inadequate control

2020 ◽  
Vol 8 (1) ◽  
pp. e001346
Author(s):  
Carlos K H Wong ◽  
Kenneth K C Man ◽  
Esther W Y Chan ◽  
Tingting Wu ◽  
Emily T Y Tse ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Cancer Mortality ◽  
Dual Therapy ◽  
Increased Risk ◽  
Dipeptidyl Peptidase 4 Inhibitors ◽  
All Cause Mortality ◽  
Risk Of Cancer

IntroductionThis study aims to compare the risks of cancer among patients with type 2 diabetes mellitus (T2DM) on metformin–sulfonylurea dual therapy intensified with dipeptidyl peptidase 4 inhibitors (DPP4i), thiazolidinediones, or insulin.Research design and methodsWe assembled a retrospective cohort data of 20 577 patients who were free of cancer and on metformin–sulfonylurea dual therapy, and whose drug treatments were intensified with DPP4i (n=9957), insulin (n=7760), or thiazolidinediones (n=2860) from January 2006 to December 2017. Propensity-score weighting was used to balance out baseline covariates across the three groups. HRs for any types of cancer, cancer mortality, and all-cause mortality were assessed using Cox proportional-hazards models.ResultsOver a mean follow-up period of 34 months with 58 539 person-years, cumulative incidences of cancer, cancer mortality, and all-cause mortality were 0.028, 0.009, and 0.072, respectively. Patients intensified with insulin had the highest incidence of all-cause mortality (incidence rate=3.22/100 person-years) and the insulin itself posed the greatest risk (HR 2.46, 95% CI 2.25 to 2.70, p<0.001; 2.44, 95% CI 2.23 to 2.67) compared with thiazolidinediones and DPP4i, respectively. Comparing between thiazolidinediones and DPP4i, thiazolidinediones was associated with higher risk of cancer (HR 1.43, 95% CI 1.25 to 1.63) but not cancer mortality (HR 1.21, 95% CI 0.92 to 1.58) and all-cause mortality (HR 0.99, 95% CI 0.88 to 1.11). Insulin was associated with the greatest risk of cancer mortality (HR 1.36, 95% CI 1.09 to 1.71; 1.65, 95% CI 1.31 to 2.07) compared with thiazolidinediones and DPP4i, respectively.ConclusionsFor patients with T2DM on metformin–sulfonylurea dual therapy, the addition of DPP4i was the third-line medication least likely to be associated with cancer mortality and cancer effect among three options, and posed no increased risk for all-cause mortality when compared with thiazolidinediones.

scholarly journals Role of statin in increasing the risk of diabetes mellitus

2017 ◽  
Vol 4 (12) ◽  
pp. 1850
Author(s):  
Mahdi Mohammadian ◽  
Hamid Salehiniya ◽  
Jamshid Ovisey ◽  
Fatemeh Allah Bakeshei ◽  
Abdollah Mohammadian-Hafshejani
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Cardiovascular Diseases ◽  
Blood Sugar ◽  
Glycosylated Hemoglobin ◽  
The United States ◽  
Increased Risk ◽  
Sugar Levels

Statin is known as one of the most commonly prescribed medicines in the United States (Bhattacharya et al., 2014). This drug is widely used with the aim to prevent risk of stroke and cardiovascular diseases as well as reduction of mortality from these diseases (Mohammadian et al., 2015; Ong et al., 2014). Several studies have recently paid attention to roles of Statins in increasing the risk of type 2 diabetes mellitus. Based on results of several clinical trials on prevention of cardiovascular diseases, Statin leads to an increased risk of type 2 diabetes mellitus (T2DM) (Crandall et al., 2017). This drug leads to an increase at fasting blood sugar, glycosylated hemoglobin (HbA1c) and blood sugar levels in recipients (Mohammadian et al., 2017; Ridker et al., 2012).

scholarly journals Relationship Of Stress Levels And Diet With Blood Sugar Levels In Patients Of Type 2 Diabetes Mellitus

2020 ◽  
Vol 9 (1) ◽  
pp. 241-247
Author(s):  
Ninik Ambar Sari ◽  
Ceria Nurhayati ◽  
Sri Anik Rustini
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Blood Sugar ◽  
Fasting Blood Glucose ◽  
Sampling Technique ◽  
The Body ◽  
Cross Sectional ◽  
Sugar Levels

Diabetes mellitus type 2 is a condition in which the body tissue doesn’t respond to the action of insulin. Type 2 DM can cause complications if it doesn’t managed properly, good DM management behavior for patients needs to be done by maintaining a healthy diet and stress will increase blood sugar levels. This study uses analytic cross sectional design. The sampling technique in this study was purposive sampling of 60 respondents. Data processing using the SPSS program with the Spearman Rho test. Results: a correlation between stress level and fasting blood glucose level of type 2 diabetes mellitus patients with a correlation value of 0.544, which is located between 0.4 - <0.6, is in the medium category. While the statistical test for diet obtained a significant number or ρ = 0.002 then Ho is rejected, H1 is accepted.

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