ASSESSMENT OF THE PROBABLE RELATIONSHIP OF EXACERBATIONS OF CARDIOVASCULAR DISEASES WITH THE METEOROLOGICAL SITUATION

2021 ◽  
pp. 63-69
Author(s):  
Berezhnova T.A. ◽  
Kulintsova Ya.V. ◽  
Maslov O.V. ◽  
Kolyagina N.M. ◽  
Ponomaryova E.Yu.
Keyword(s):  
Heart Failure ◽  
Cardiovascular Diseases ◽  
Medical Care ◽  
Cardiovascular System ◽  
Atmospheric Pressure ◽  
Vascular Lesions ◽  
Scientific Publications ◽  
Probable Relationship ◽  
Meteorological Situation ◽  
Relationship Of

Relevance. The analysis of these scientific publications has shown the relevance of studying the problem of the influence of sudden changes in meteorological factors on the functioning of the cardiovascular system, exacerbation of its leading diseases – arterial hypertension, brain vascular lesions, cerebrovascular diseases, angina. Aim: to identify the probable relationship of exacerbations of diseases of the cardiovascular system with the meteorological situation. Material and methods. A sample of data on the daily number of cases of patients 'requests for medical care to the registry of the Voronezh City Polyclinic No. 18 for 2018 was conducted. Results. At a temperature below-200C, which was registered on 27.02.2018, the number of requests for medical care due to hypertension without heart failure is 88 cases, with a diagnosis of brain vascular damage (specified) – 15, with a diagnosis of cerebrovascular disease-16, hypertension with heart failure-2, angina-0. The difference in the average daily temperature of more than 8 0C was recorded in 204 of 365 days. Out of 365 days, the atmospheric pressure drop of more than 6 mm Hg per day was recorded 52 times. Conclusions. The most informative characteristic of the six meteorological indicators taken into account in the study is a sharp drop in atmospheric pressure during the day, with which the number of cases of patients with cardiovascular diseases seeking medical care is statistically significantly correlated.

scholarly journals Assessment of the relationship of exacerbations of diseases of the cardiovascular system with the meteorological situation

2021 ◽  
Vol 100 (12) ◽  
pp. 1350-1358
Author(s):  
Natalia M. Kolyagina ◽  
Tat'jana A. Berezhnova ◽  
Nikolaj P. Mamchik ◽  
Oleg V. Klepikov ◽  
Sergej A. Yeprintsev
Keyword(s):  
Cardiovascular Diseases ◽  
Medical Care ◽  
Cardiovascular System ◽  
Atmospheric Pressure ◽  
Meteorological Factors ◽  
Ambient Air ◽  
Medical Assistance ◽  
Meteorological Situation ◽  
The Impact ◽  
The Relationship

Introduction. The impact of weather factors on the occurrence of exacerbations of diseases in meteodependent people is currently one of the actively studied problems of medicine. The aim of the study was to identify the relationship between exacerbations of diseases of the cardiovascular system with the meteorological situation to substantiate the need for preventive and informational work with meteodependent patients. Material and research methods. The study used daily data on the number of patients with cardiovascular diseases seeking medical care at Voronezh City Polyclinic No. 18 and daily information on weather conditions for 2018. The ratio of the average number of cases of medical assistance requests on days unfavourable for meteorological factors to the average number of cases of medical assistance requests per day during the year was calculated. Using software (Statistica Base V6.1), a correlation analysis of the relationship between the number of medical requests and meteorological factors was carried out. Results. It has been established that the appealability of patients with cardiovascular diseases for medical care on days unfavourable for meteorological factors is 1.1-2.0 times higher than the average annual indicator. The most informative characteristic of the six meteorological indicators taken into account in the study (average daily, minimum, maximum ambient air temperature; temperature drops by more than eight °C per day; atmospheric pressure; atmospheric pressure drops by 12 mm Hg per day or more) is a sharp drop in atmospheric pressure during the day, with which statistically significant (p <0.05) correlates the number of cases of patients with cardiovascular diseases seeking medical help. Conclusion. In medical institutions providing primary health care, it is advisable to single out separate groups of patients with meteorological dependence for dynamic observation and conduct information work with them to mitigate the severity of the course of diseases of the cardiovascular system on days unfavourable according to meteorological indicators.

ADVERSE METEOROLOGICAL SITUATION AS A RISK FACTOR FOR CARDIOVASCULAR DISEASES

2021 ◽  
pp. 28-33
Author(s):  
Kolyagina N.M. ◽  
Berezhnova T.A. ◽  
Kulintsova Ya.V. ◽  
Elistratova O.S. ◽  
Drapalyuk M.A.
Keyword(s):  
Risk Factors ◽  
Heart Failure ◽  
Cardiovascular Diseases ◽  
Medical Care ◽  
Air Temperature ◽  
Meteorological Factors ◽  
Vascular Lesions ◽  
Weather Sensitivity ◽  
Access To Medical Care ◽  
The City

Relevance. Exacerbation of the disease, as a rule, leads to the patient seeking medical help. In this regard, data on the population's access to medical care can serve as an indicator of the exacerbation of the disease. Aim: to analyze meteorological risk factors that contribute to the development of cardiovascular diseases. Material and methods. The ratio of the average number of cases of requests for medical care on unfavorable days for meteorological factors to the average number of cases of requests per day for medical care during the year was calculated. Using software tools (STATISTICA Base V6. 1), the type of data distribution was estimated, and a correlation analysis of the likely relationship between the number of medical care requests and the indicators of meteorological factors was carried out. Results. As a result of the study, it was found that the average number of cases of medical care requests on hot days (air temperature over + 300C) is 1.1-1.4 times higher than the average number of cases of requests per day for the same reasons (diagnoses) during the year and is abnormal for the territory of the city of Voronezh, due to such diagnoses as hypertension without heart failure, brain vascular lesions (specified), cerebrovascular disease, hypertension with heart failure. Conclusions. Thus, it was found that one of the meteorological risk factors for the formation of cardiovascular pathology is high air temperature (above + 300C), which is the goal for the implementation of the main directions of prevention of increased weather sensitivity and treatment of weather-dependent patients.

ASSESSMENT OF THE TREATMENT OF PATIENTS WITH DISEASES OF THE CARDIOVASCULAR SYSTEM FOR MEDICAL CARE IN UNFAVORABLE WEATHER FACTORS DAYS

2021 ◽  
pp. 117-123
Author(s):  
Kolyagina N.M. ◽  
Berezhnova T.A. ◽  
Kulintsova Ya.V. ◽  
Elistratova O.S. ◽  
Drapalyuk M.A.
Keyword(s):  
Heart Failure ◽  
Cardiovascular Diseases ◽  
Medical Care ◽  
Atmospheric Pressure ◽  
Daily Maximum ◽  
Hypertensive Disease ◽  
Weather Factors ◽  
Atmospheric Air ◽  
Air Temperatures ◽  
Unfavorable Weather

Relevance. The impact of weather factors on the occurrence of exacerbations of diseases in weather-dependent people is currently one of the actively studied problems of medicine. A number of authors draw attention to the need to correct the functional status of weather-dependent patients with cardiovascular diseases in unfavorable weather conditions. Aim: to assess the possible relationship between the manifestations of exacerbations of cardiovascular pathology and adverse weather factors. Material and methods. The materials of the regional center for Hydrometeorology and environmental monitoring were used, and a database was formed that includes information on the average daily, maximum and minimum atmospheric air temperatures, and atmospheric pressure for each day of 2018. Results. Meteorological risk factors for exacerbation of cardiovascular diseases in the Central European part of Russia include uncharacteristic heat (above +30 0C) or severe frost (below -20 0C), sudden changes in air temperature (by 8 0C or more, both in the direction of its increase and decrease), atmospheric pressure drops of more than 6 mm Hg during the day. It is established that the range of changes in meteorological indicators during the annual cycle is quite wide. Conclusions. Evaluation of the relationship between the treatment of patients with leading forms of cardiovascular diseases for medical care and meteorological indicators (average daily, maximum and minimum atmospheric air temperatures, atmospheric pressure) showed that with the advance of the case of the disease by 1 day (hypertensive disease without heart failure, brain vascular lesions, cerebrovascular disease, hypertensive disease with heart failure, angina pectoris), statistically significant links of weak and moderate strength were revealed.

LEARNING OF THE RELATIONSHIP BETWEEN EXACERBATION OF CARDIOVASCULAR PATHOLOGY AND METEOROLOGICAL FACTORS

2021 ◽  
pp. 110-116
Author(s):  
Klepikov O.V. ◽  
Berezhnova T.A. ◽  
Kulintsova Ya.V. ◽  
Kolyagina N.M.
Keyword(s):  
Heart Failure ◽  
Medical Care ◽  
Cardiovascular System ◽  
Meteorological Factors ◽  
Circulatory System ◽  
Vascular Lesions ◽  
Cardiovascular Pathology ◽  
Air Temperatures ◽  
The Relationship ◽  
The City

Relevance. The problem of weather dependence, including diseases of the circulatory system, is debatable, and, therefore, requires research in order to find ways to improve the provision of medical care to the population and improve its quality. Aim: to study the influence of meteorological factors on the treatment of the population with diseases of the cardiovascular system for medical care. Material and methods. The ratio of the average number of cases of requests for medical care on unfavorable days for meteorological factors to the average number of cases of requests per day for medical care during 2018 was calculated. Results. The average number of cases of requests for medical care on hot days when the air temperature rose above + 300C, which is abnormal for the territory of the city of Voronezh, due to such diagnoses as hypertension without heart failure, brain vascular lesions (specified), cerebrovascular disease, hypertension with heart failure, is 1.1-1.4 times higher than the average number of cases of requests per day for the same reasons (diagnoses) during the year. At the same time, low air temperatures, which are not typical for this area, can also act as a factor contributing to the exacerbation of diseases of the cardiovascular system. Conclusion. The assessment of the relationship between the treatment of patients with leading forms of cardiovascular diseases for medical care and meteorological indicators showed that with the advance of the case of the disease by 1 day with meteorological indicators, according to the results of the correlation analysis, statistically significant links of weak and medium strength were revealed.

Relationship of thyroid dysfunction with cardiovascular diseases: updated review on heart failure progression

HORMONES ◽  
2020 ◽  
Vol 19 (3) ◽  
pp. 301-309
Author(s):  
Adel Abdel-Moneim ◽  
Asmaa M. Gaber ◽  
Sherouk Gouda ◽  
Aya Osama ◽  
Sarah I. Othman ◽  
...  
Keyword(s):  
Heart Failure ◽  
Cardiovascular Diseases ◽  
Thyroid Dysfunction ◽  
Heart Failure Progression ◽  
Relationship Of

scholarly journals Cardiovascular system status of long-livers in Moscow: the prevalence of cardiovascular diseases and their risk factors

2021 ◽  
Vol 26 ◽  
pp. 4028
Author(s):  
K. A. Eruslanova ◽  
A. V. Luzina ◽  
Yu. S. Onuchina ◽  
V. S. Ostapenko ◽  
N. V. Sharashkina ◽  
...  
Keyword(s):  
Risk Factors ◽  
Heart Failure ◽  
Cardiovascular Diseases ◽  
Cardiovascular System ◽  
Interventricular Septum ◽  
Systolic Heart Failure ◽  
Left Ventricular ◽  
Past Century ◽  
Cvd Risk Factors ◽  
Cvd Risk

Over the past century, an increase in life expectancy has been observed in Russia and in the world. According to the United Nations, by 2100, the number of centenarians worldwide will reach 25 million. Despite the annual increase in the number of super-centenarians, this age group remains poorly understood.Aim. To estimate the prevalence of cardiovascular diseases (CVD) and the main risk factors among super-centenarians in Moscow.Material and methods. According to the register of long-livers in Moscow, 82 people aged 95 to 105 were included. Participants were examined at home.The history of life and the presence of chronic diseases was collected by participant words. To assess the state of cardiovascular system, an ultrasound of the heart and main arteries was performed.Results. Conventional CVD risk factors were the exception rather than the rule among study participants (smoking — 8 patients (9,8%), alcohol abuse — 4 (4,9%), obesity — 6 (7,3%)). Dyslipidemia was relatively widespread (n=37; 45,1%), however, there were no pronounced abnormalities in the lipid profile: the maximum increase in low-density lipoproteins was 5,6 mmol/L. The most common CVDs among the participants were hypertension (n=64; 78%), coronary artery disease (n=42; 51,2%), and heart failure (n=26; 31,7%); other diseases were much less common. The most common echocardiographic changes were left atrial dilatation (n=38; 74,5%), increased left ventricular mass, thickening of left ventricular posterior wall (n=24; 48%) and interventricular septum (n=51; 100%). Diastolic and systolic heart failure were not widespread among long-livers: 16 (32%) and 2 (3,9%), respectively. Despite a rather large number of atherosclerotic plaques in the common carotid and femoral arteries, the number of hemodynamically significant plaques was low (n=3; 4,6%). An intima-media thickening up to 1,0-1,1 mm was found.Conclusion. Long-livers in Moscow are characterized by a low prevalence of traditional CVD risk factors (with the exception of hypertension) and a fairly high prevalence of atherosclerotic CVDs, which are characterized by a subclinical course.

ERECTILE DYSFUNCTION AS A PREDICTOR AND A COMPANION OF CARDIOVASCULAR DISEASE

2021 ◽  
pp. 178-182
Author(s):  
Анна Сергеевна Смольянникова ◽  
Ирина Сергеевна Добрынина ◽  
Анна Александровна Зуйкова ◽  
Елена Анатольевна Ханина ◽  
Марина Николаевна Муравицкая
Keyword(s):  
Blood Pressure ◽  
Erectile Dysfunction ◽  
Cardiovascular Diseases ◽  
High Strength ◽  
Vascular Lesions ◽  
Control Group ◽  
Endocrine Disorders ◽  
Cardiovascular Pathology ◽  
Relationship Of ◽  
The Relationship

Эректильная дисфункция - патология, связанная не только с наличием у больного урологических, психических или эндокринных нарушений. Нарушению эректильной функции способствуют многочисленные факторы, в том числе кардиоваскулярные заболевания, к которым в частности относится атеросклеротическое поражение сосудов на фоне дислипидемии. Эректильная дисфункция часто является первым симптомом системного атеросклероза. Целью исследования является изучение связи эректильной дисфункции и уровня тестостерона крови с дислипидемией и частными проявлениями сердечно-сосудистой патологии для своевременного выявления и начала лечения латентных форм кардиоваскулярных заболеваний. Была проведена оценка соответствующих показателей у выделенных групп исследуемых: основная группа - больные, обратившиеся за помощью по поводу эректильной дисфункции, контрольная группа - относительно здоровые исследуемые, не предъявляющие жалоб на эректильную функцию. В результате оценки полученных данных между количеством баллов, набранных по тесту-опроснику МИЭФ-5, уровнем тестостерона и показателями сАД, дАД, SCORE, общего холестерина и коэффициентом атерогенности выявлены связи умеренной и высокой силы. Пациенты, обратившиеся за амбулаторной помощью по поводу эректильной дисфункции, имели высокие показатели коэффициента атерогенности, что свидетельствует о высокой вероятности атеросклеротического поражения сосудов и в дальнейшем развития сердечно-сосудистой патологии Erectile dysfunction is a pathology associated not only with the presence of urological, mental or endocrine disorders in the patient. Numerous factors contribute to the development of erectile dysfunction, including cardiovascular diseases, which in particular include atherosclerotic vascular damage on the background of dyslipidemia. Erectile dysfunction caused by arteriosclerosis of the penile arteries is often the first symptom of systemic arteriosclerosis. The aim of this research is to study the relationship of erectile dysfunction and blood testosterone levels with dyslipidemia and particular manifestations of cardiovascular pathology for the timely detection and initiation of treatment of latent forms of cardiovascular diseases. To do this, the corresponding indicators were evaluated in the selected groups of subjects: the main group - patients who sought help for erectile dysfunction, the control group-relatively healthy subjects who did not complain about their erectile function. As a result of evaluating the data obtained between the number of points scored according to the MIEF-5 test-questionnaire, the level of testosterone and indicators of systolic blood pressure, diastolic blood pressure, SCORE, total cholesterol and the coefficient of atherogenicity, moderate and high strength relationships were revealed. Patients seeking outpatient care for erectile dysfunction had high rates of atherogenic coefficient, which indicates a high probability of atherosclerotic vascular lesions and further development of cardiovascular pathology

scholarly journals Vasopressin & Oxytocin in Control of the Cardiovascular System: An Updated Review

2019 ◽  
Vol 18 (1) ◽  
pp. 14-33 ◽  
Author(s):  
Nina Japundžić-Žigon ◽  
Maja Lozić ◽  
Olivera Šarenac ◽  
David Murphy
Keyword(s):  
Heart Failure ◽  
Congestive Heart Failure ◽  
Cardiovascular Diseases ◽  
Water Balance ◽  
Cardiovascular System ◽  
Circulatory Collapse ◽  
Advanced Stages ◽  
The Brain ◽  
Peripheral Action

Since the discovery of vasopressin (VP) and oxytocin (OT) in 1953, considerable knowledge has been gathered about their roles in cardiovascular homeostasis. Unraveling VP vasoconstrictor properties and V1a receptors in blood vessels generated powerful hemostatic drugs and drugs effective in the treatment of certain forms of circulatory collapse (shock). Recognition of the key role of VP in water balance via renal V2 receptors gave birth to aquaretic drugs found to be useful in advanced stages of congestive heart failure. There are still unexplored actions of VP and OT on the cardiovascular system, both at the periphery and in the brain that may open new venues in treatment of cardiovascular diseases. After a brief overview on VP, OT and their peripheral action on the cardiovascular system, this review focuses on newly discovered hypothalamic mechanisms involved in neurogenic control of the circulation in stress and disease.

Inflammageing in the cardiovascular system: mechanisms, emerging targets, and novel therapeutic strategies

2020 ◽  
Vol 134 (17) ◽  
pp. 2243-2262
Author(s):  
Danlin Liu ◽  
Gavin Richardson ◽  
Fehmi M. Benli ◽  
Catherine Park ◽  
João V. de Souza ◽  
...  
Keyword(s):  
Cardiovascular Diseases ◽  
Cardiovascular System ◽  
Nlrp3 Inflammasome ◽  
Molecular Mechanisms ◽  
Molecular Targets ◽  
Therapeutic Interventions ◽  
Low Grade ◽  
Cardiovascular Research ◽  
Inflammatory Processes ◽  
Ach Receptors

Abstract In the elderly population, pathological inflammation has been associated with ageing-associated diseases. The term ‘inflammageing’, which was used for the first time by Franceschi and co-workers in 2000, is associated with the chronic, low-grade, subclinical inflammatory processes coupled to biological ageing. The source of these inflammatory processes is debated. The senescence-associated secretory phenotype (SASP) has been proposed as the main origin of inflammageing. The SASP is characterised by the release of inflammatory cytokines, elevated activation of the NLRP3 inflammasome, altered regulation of acetylcholine (ACh) nicotinic receptors, and abnormal NAD+ metabolism. Therefore, SASP may be ‘druggable’ by small molecule therapeutics targeting those emerging molecular targets. It has been shown that inflammageing is a hallmark of various cardiovascular diseases, including atherosclerosis, hypertension, and adverse cardiac remodelling. Therefore, the pathomechanism involving SASP activation via the NLRP3 inflammasome; modulation of NLRP3 via α7 nicotinic ACh receptors; and modulation by senolytics targeting other proteins have gained a lot of interest within cardiovascular research and drug development communities. In this review, which offers a unique view from both clinical and preclinical target-based drug discovery perspectives, we have focused on cardiovascular inflammageing and its molecular mechanisms. We have outlined the mechanistic links between inflammageing, SASP, interleukin (IL)-1β, NLRP3 inflammasome, nicotinic ACh receptors, and molecular targets of senolytic drugs in the context of cardiovascular diseases. We have addressed the ‘druggability’ of NLRP3 and nicotinic α7 receptors by small molecules, as these proteins represent novel and exciting targets for therapeutic interventions targeting inflammageing in the cardiovascular system and beyond.

PERSONALIZED APPROACH TO THE ORGANIZATION OF MEDICAL CARE FOR PATIENTS WITH WEATHER DEPENDENCE

2020 ◽  
pp. 35-39
Author(s):  
Klepikov O.V. ◽  
Kolyagina N.M. ◽  
Berezhnova T.A. ◽  
Kulintsova Ya.V.
Keyword(s):  
Medical Care ◽  
Cardiovascular System ◽  
Performance Indicators ◽  
Weather Conditions ◽  
Climatic Conditions ◽  
Outpatient Clinics ◽  
Vulnerable Groups ◽  
Pathological Effect ◽  
Weather Forecasts ◽  
Personalized Approach

Relevance. Today, in preventive medicine, climatic conditions that have a pathological effect on the functional state of a person are increasingly being updated. the occurrence of exacerbations of many diseases can be causally associated with various weather conditions. Aim: to develop the main tasks for improving the organization of medical care for weather-dependent patients with diseases of the cardiovascular system. Material and methods. The assessment of personnel, material and technical support and the main performance indicators of an outpatient clinic was carried out on the example of the Voronezh city polyclinic No. 18 to develop the main tasks for improving the organization of medical care for weather-dependent patients with diseases of the cardiovascular system. Results. The main personnel problem is the low staffing of district therapists and specialists of a narrow service. One of the priorities for reducing the burden on medical hospitals is the organization of inpatient replacement medical care on the basis of outpatient clinics. The indicators for the implementation of state guarantees for the outpatient network for 2018, which were fully implemented, are given. The analysis of the planned load performance by polyclinic specialists is presented. Cardiological and neurological services carry out measures to reduce the risk of exacerbations of diseases with cerebral atherosclerosis, hypertension, and major neurological nosologies. Conclusion. Improving the organization of medical care for weather-dependent patients with cardiovascular diseases are: informing patients about the sources of specialized medical weather forecasts in the region, organizing the work of the medical prevention office, implementing an interdepartmental approach to providing health care to the most vulnerable groups of the population.

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