ASSESSMENT OF THE TREATMENT OF PATIENTS WITH DISEASES OF THE CARDIOVASCULAR SYSTEM FOR MEDICAL CARE IN UNFAVORABLE WEATHER FACTORS DAYS

2021 ◽  
pp. 117-123
Author(s):  
Kolyagina N.M. ◽  
Berezhnova T.A. ◽  
Kulintsova Ya.V. ◽  
Elistratova O.S. ◽  
Drapalyuk M.A.
Keyword(s):  
Heart Failure ◽  
Cardiovascular Diseases ◽  
Medical Care ◽  
Atmospheric Pressure ◽  
Daily Maximum ◽  
Hypertensive Disease ◽  
Weather Factors ◽  
Atmospheric Air ◽  
Air Temperatures ◽  
Unfavorable Weather

Relevance. The impact of weather factors on the occurrence of exacerbations of diseases in weather-dependent people is currently one of the actively studied problems of medicine. A number of authors draw attention to the need to correct the functional status of weather-dependent patients with cardiovascular diseases in unfavorable weather conditions. Aim: to assess the possible relationship between the manifestations of exacerbations of cardiovascular pathology and adverse weather factors. Material and methods. The materials of the regional center for Hydrometeorology and environmental monitoring were used, and a database was formed that includes information on the average daily, maximum and minimum atmospheric air temperatures, and atmospheric pressure for each day of 2018. Results. Meteorological risk factors for exacerbation of cardiovascular diseases in the Central European part of Russia include uncharacteristic heat (above +30 0C) or severe frost (below -20 0C), sudden changes in air temperature (by 8 0C or more, both in the direction of its increase and decrease), atmospheric pressure drops of more than 6 mm Hg during the day. It is established that the range of changes in meteorological indicators during the annual cycle is quite wide. Conclusions. Evaluation of the relationship between the treatment of patients with leading forms of cardiovascular diseases for medical care and meteorological indicators (average daily, maximum and minimum atmospheric air temperatures, atmospheric pressure) showed that with the advance of the case of the disease by 1 day (hypertensive disease without heart failure, brain vascular lesions, cerebrovascular disease, hypertensive disease with heart failure, angina pectoris), statistically significant links of weak and moderate strength were revealed.

ASSESSMENT OF THE PROBABLE RELATIONSHIP OF EXACERBATIONS OF CARDIOVASCULAR DISEASES WITH THE METEOROLOGICAL SITUATION

2021 ◽  
pp. 63-69
Author(s):  
Berezhnova T.A. ◽  
Kulintsova Ya.V. ◽  
Maslov O.V. ◽  
Kolyagina N.M. ◽  
Ponomaryova E.Yu.
Keyword(s):  
Heart Failure ◽  
Cardiovascular Diseases ◽  
Medical Care ◽  
Cardiovascular System ◽  
Atmospheric Pressure ◽  
Vascular Lesions ◽  
Scientific Publications ◽  
Probable Relationship ◽  
Meteorological Situation ◽  
Relationship Of

Relevance. The analysis of these scientific publications has shown the relevance of studying the problem of the influence of sudden changes in meteorological factors on the functioning of the cardiovascular system, exacerbation of its leading diseases – arterial hypertension, brain vascular lesions, cerebrovascular diseases, angina. Aim: to identify the probable relationship of exacerbations of diseases of the cardiovascular system with the meteorological situation. Material and methods. A sample of data on the daily number of cases of patients 'requests for medical care to the registry of the Voronezh City Polyclinic No. 18 for 2018 was conducted. Results. At a temperature below-200C, which was registered on 27.02.2018, the number of requests for medical care due to hypertension without heart failure is 88 cases, with a diagnosis of brain vascular damage (specified) – 15, with a diagnosis of cerebrovascular disease-16, hypertension with heart failure-2, angina-0. The difference in the average daily temperature of more than 8 0C was recorded in 204 of 365 days. Out of 365 days, the atmospheric pressure drop of more than 6 mm Hg per day was recorded 52 times. Conclusions. The most informative characteristic of the six meteorological indicators taken into account in the study is a sharp drop in atmospheric pressure during the day, with which the number of cases of patients with cardiovascular diseases seeking medical care is statistically significantly correlated.

ADVERSE METEOROLOGICAL SITUATION AS A RISK FACTOR FOR CARDIOVASCULAR DISEASES

2021 ◽  
pp. 28-33
Author(s):  
Kolyagina N.M. ◽  
Berezhnova T.A. ◽  
Kulintsova Ya.V. ◽  
Elistratova O.S. ◽  
Drapalyuk M.A.
Keyword(s):  
Risk Factors ◽  
Heart Failure ◽  
Cardiovascular Diseases ◽  
Medical Care ◽  
Air Temperature ◽  
Meteorological Factors ◽  
Vascular Lesions ◽  
Weather Sensitivity ◽  
Access To Medical Care ◽  
The City

Relevance. Exacerbation of the disease, as a rule, leads to the patient seeking medical help. In this regard, data on the population's access to medical care can serve as an indicator of the exacerbation of the disease. Aim: to analyze meteorological risk factors that contribute to the development of cardiovascular diseases. Material and methods. The ratio of the average number of cases of requests for medical care on unfavorable days for meteorological factors to the average number of cases of requests per day for medical care during the year was calculated. Using software tools (STATISTICA Base V6. 1), the type of data distribution was estimated, and a correlation analysis of the likely relationship between the number of medical care requests and the indicators of meteorological factors was carried out. Results. As a result of the study, it was found that the average number of cases of medical care requests on hot days (air temperature over + 300C) is 1.1-1.4 times higher than the average number of cases of requests per day for the same reasons (diagnoses) during the year and is abnormal for the territory of the city of Voronezh, due to such diagnoses as hypertension without heart failure, brain vascular lesions (specified), cerebrovascular disease, hypertension with heart failure. Conclusions. Thus, it was found that one of the meteorological risk factors for the formation of cardiovascular pathology is high air temperature (above + 300C), which is the goal for the implementation of the main directions of prevention of increased weather sensitivity and treatment of weather-dependent patients.

scholarly journals Assessment of the relationship of exacerbations of diseases of the cardiovascular system with the meteorological situation

2021 ◽  
Vol 100 (12) ◽  
pp. 1350-1358
Author(s):  
Natalia M. Kolyagina ◽  
Tat'jana A. Berezhnova ◽  
Nikolaj P. Mamchik ◽  
Oleg V. Klepikov ◽  
Sergej A. Yeprintsev
Keyword(s):  
Cardiovascular Diseases ◽  
Medical Care ◽  
Cardiovascular System ◽  
Atmospheric Pressure ◽  
Meteorological Factors ◽  
Ambient Air ◽  
Medical Assistance ◽  
Meteorological Situation ◽  
The Impact ◽  
The Relationship

Introduction. The impact of weather factors on the occurrence of exacerbations of diseases in meteodependent people is currently one of the actively studied problems of medicine. The aim of the study was to identify the relationship between exacerbations of diseases of the cardiovascular system with the meteorological situation to substantiate the need for preventive and informational work with meteodependent patients. Material and research methods. The study used daily data on the number of patients with cardiovascular diseases seeking medical care at Voronezh City Polyclinic No. 18 and daily information on weather conditions for 2018. The ratio of the average number of cases of medical assistance requests on days unfavourable for meteorological factors to the average number of cases of medical assistance requests per day during the year was calculated. Using software (Statistica Base V6.1), a correlation analysis of the relationship between the number of medical requests and meteorological factors was carried out. Results. It has been established that the appealability of patients with cardiovascular diseases for medical care on days unfavourable for meteorological factors is 1.1-2.0 times higher than the average annual indicator. The most informative characteristic of the six meteorological indicators taken into account in the study (average daily, minimum, maximum ambient air temperature; temperature drops by more than eight °C per day; atmospheric pressure; atmospheric pressure drops by 12 mm Hg per day or more) is a sharp drop in atmospheric pressure during the day, with which statistically significant (p <0.05) correlates the number of cases of patients with cardiovascular diseases seeking medical help. Conclusion. In medical institutions providing primary health care, it is advisable to single out separate groups of patients with meteorological dependence for dynamic observation and conduct information work with them to mitigate the severity of the course of diseases of the cardiovascular system on days unfavourable according to meteorological indicators.

LEARNING OF THE RELATIONSHIP BETWEEN EXACERBATION OF CARDIOVASCULAR PATHOLOGY AND METEOROLOGICAL FACTORS

2021 ◽  
pp. 110-116
Author(s):  
Klepikov O.V. ◽  
Berezhnova T.A. ◽  
Kulintsova Ya.V. ◽  
Kolyagina N.M.
Keyword(s):  
Heart Failure ◽  
Medical Care ◽  
Cardiovascular System ◽  
Meteorological Factors ◽  
Circulatory System ◽  
Vascular Lesions ◽  
Cardiovascular Pathology ◽  
Air Temperatures ◽  
The Relationship ◽  
The City

Relevance. The problem of weather dependence, including diseases of the circulatory system, is debatable, and, therefore, requires research in order to find ways to improve the provision of medical care to the population and improve its quality. Aim: to study the influence of meteorological factors on the treatment of the population with diseases of the cardiovascular system for medical care. Material and methods. The ratio of the average number of cases of requests for medical care on unfavorable days for meteorological factors to the average number of cases of requests per day for medical care during 2018 was calculated. Results. The average number of cases of requests for medical care on hot days when the air temperature rose above + 300C, which is abnormal for the territory of the city of Voronezh, due to such diagnoses as hypertension without heart failure, brain vascular lesions (specified), cerebrovascular disease, hypertension with heart failure, is 1.1-1.4 times higher than the average number of cases of requests per day for the same reasons (diagnoses) during the year. At the same time, low air temperatures, which are not typical for this area, can also act as a factor contributing to the exacerbation of diseases of the cardiovascular system. Conclusion. The assessment of the relationship between the treatment of patients with leading forms of cardiovascular diseases for medical care and meteorological indicators showed that with the advance of the case of the disease by 1 day with meteorological indicators, according to the results of the correlation analysis, statistically significant links of weak and medium strength were revealed.

NT-PROBNP AND THE CUT-OFF VALUE IN CARDIOVASCULAR DISEASES

2011 ◽  
pp. 5-12
Author(s):  
Anh Tien Hoang ◽  
Van Minh Huynh ◽  
Khanh Hoang ◽  
Huu Dang Tran ◽  
Viet An Tran
Keyword(s):  
Heart Failure ◽  
Cardiovascular Disease ◽  
Pilot Study ◽  
Cardiovascular Diseases ◽  
Clinical Application ◽  
European Society ◽  
The Other ◽  
Cardiac Marker ◽  
Cardiac Biomarker ◽  
European Society Of Cardiology

NT-ProBNP is a high value cardiac biomarker and widely applies in many cardiovascular diseases. The evaluation of concentration of NT-ProBNP needs the concern about age, gender, obesity and especially we need each cut-off point for each cause of cardiovascular disease in evaluation and clinical application. Because NT-ProBNP is a new cardiac marker and has been researched in 5 recent years, the cut-off of NT-ProBNP is still being studied for the clinical application in cardiovascular diseases. Only the cut-off of NT-ProBNP in diagnosis heart failure was guided by European Society of Cardiology. The meaning of introduce cut-off value of value plays an role as pilot study for the other relate study and brings the NT-ProBNP closely approach to clinical application.

RELATIONSHIP BETWEEN CARDIOVASCULAR DISEASES AND ANATOMOSIS OF ARTERIOVENOUS FISTULAR IN PATIENTS WITH REGULARLY HEMODIALYSIS

2017 ◽  
pp. 88-92
Author(s):  
Van Hien Pham ◽  
Huu Vu Quang Nguyen ◽  
Tam Vo
Keyword(s):  
Heart Failure ◽  
Blood Pressure ◽  
Renal Failure ◽  
Chronic Renal Failure ◽  
Cardiovascular Diseases ◽  
Systolic Blood Pressure ◽  
Diastolic Blood Pressure ◽  
Negative Correlation ◽  
Mean Value ◽  
The Mean

Background: Cardiovascular diseases are the leading cause of death in patients with chronic renal failure. When a patient undergoes dialysis, making AVF or AVG causes cardiovascular events. Understanding the relationship between complications: hypertension, heart failure, AVF or AVG (formation time, position, diameter) helps us monitor, detect, prevent and treatment of complications to limit the risk of death in patients with dialysis. Objective: Relationship between cardiovascular diseases and anatomosis of arteriovenous fistular in patients with regularly hemodialysis at Cho Ray Hospital. Methods: A cross-sectional study was conducted at Cho Ray Hospital from 2015 to 2016. The survey some cardiovascular diseases are done by clinical examination, tests for diagnostic imaging such as X-ray, electrocardiogram and echocardiogram: heart and diameter of anastomosis AVF, AVG. Results: The study population included 303 patients with chronic renal failure who were dialysis. Of which, patients aged 25-45 accounted for the highest proportion (43.9%). The proportion of male and female patients was similar (48.5% and 51.5% respectively). The mean value of systolic blood pressure on patients made AVF, AVG less than 12 months is higher than patients made AVF, AVG over 12 months, and there is negative correlation (r = -0.43) between AVF, AVG and systolic blood pressure (p <0.05). The mean value of diastolic blood pressure on patients made AVF, AVG less than 12 months is lower than patients made AVF, AVG over 12 months, and and there is positive correlation (r = -0.43) between AVF, AVG and diastolic blood pressure (p <0.05) (p <0.05). The prevalence of patients with heart failure made AVF, AVG over 12 months is higher than that of the under 12 months group, there is a negative correlation (r = - 0.43) between AVF, AVG diameter and EF index (p <0.05). Conclusion: It is important to note the diameter of anastomosis AVF, AVG in patients with chronic renal failure dialysis to limit cardiovascular complications, especially heart failure. Key words: Chronic kidney disease, hemodialysis.

scholarly journals Osteoprotegerin and RANKL-RANK-OPG-TRAIL signalling axis in heart failure and other cardiovascular diseases

2021 ◽  
Author(s):  
Mieczysław Dutka ◽  
Rafał Bobiński ◽  
Wojciech Wojakowski ◽  
Tomasz Francuz ◽  
Celina Pająk ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Heart Failure ◽  
Cardiovascular Diseases ◽  
Vascular Endothelial Cells ◽  
Circulatory System ◽  
Prognostic Indicator ◽  
High Plasma ◽  
Mechanisms Of Action ◽  
Left Ventricular ◽  
High Ratio

AbstractOsteoprotegerin (OPG) is a glycoprotein involved in the regulation of bone remodelling. OPG regulates osteoclast activity by blocking the interaction between the receptor activator of nuclear factor kappa B (RANK) and its ligand (RANKL). More and more studies confirm the relationship between OPG and cardiovascular diseases. Numerous studies have confirmed that a high plasma concentration of OPG and a low concentration of tumour necrosis factor–related apoptosis inducing ligand (TRAIL) together with a high OPG/TRAIL ratio are predictors of poor prognosis in patients with myocardial infarction. A high plasma OPG concentration and a high ratio of OPG/TRAIL in the acute myocardial infarction are a prognostic indicator of adverse left ventricular remodelling and of the development of heart failure. Ever more data indicates the participation of OPG in the regulation of the function of vascular endothelial cells and the initiation of the atherosclerotic process in the arteries. Additionally, it has been shown that TRAIL has a protective effect on blood vessels and exerts an anti-atherosclerotic effect. The mechanisms of action of both OPG and TRAIL within the cells of the vascular wall are complex and remain largely unclear. However, these mechanisms of action as well as their interaction in the local vascular environment are of great interest to researchers. This article presents the current state of knowledge on the mechanisms of action of OPG and TRAIL in the circulatory system and their role in cardiovascular diseases. Understanding these mechanisms may allow their use as a therapeutic target in cardiovascular diseases in the future.

scholarly journals Effects of Dust Storms and Climatological Factors on Mortality and Morbidity of Cardiovascular Diseases Admitted to ED

2018 ◽  
Vol 2018 ◽  
pp. 1-7 ◽  
Author(s):  
Behcet Al ◽  
Mustafa Bogan ◽  
Suat Zengin ◽  
Mustafa Sabak ◽  
Seval Kul ◽  
...  
Keyword(s):  
Heart Failure ◽  
Emergency Department ◽  
Chest Pain ◽  
Cardiovascular Diseases ◽  
Dust Storm ◽  
Dust Storms ◽  
Maximum Temperature ◽  
Inpatient Hospitalization ◽  
Mortality And Morbidity ◽  
Coronary Syndrome

Objective. This study was designed to investigate the effects of Desert Dust Storms and Climatological Factors on Mortality and Morbidity of Cardiovascular Diseases admitted to emergency department in Gaziantep. Method. Hospital records, obtained between September 01, 2009 and January 31, 2014, from four state hospitals in Gaziantep, Turkey, were compared to meteorological and climatological data. Statistical analysis was performed by Statistical Package for the Social Science (SPSS) for windows version 24.0. Results. 168,467 patients were included in this study. 83% of the patients had chest pain and 17% of patients had cardiac failure (CF). An increase in inpatient hospitalization due to CF was observed and corresponded to the duration of dust storms measured by number of days. However, there was no significant increase in emergency department (ED) presentations. There was no significant association of cardiac related mortality and coinciding presence of a dust storm or higher recorded temperature. The association of increases in temperature levels and the presence of dust storms with “acute coronary syndrome- (ACS-) related emergency service presentations, inpatient hospitalization, and mortality” were statistically significant. The relationship between the increase in PM10 levels due to causes unrelated to dust storms and the outpatient application, admission, and mortality due to heart failure was not significant. The increase in particle matter 10 (PM) levels due to causes outside the dust storm caused a significant increase in outpatient application, hospitalization, and mortality originated from ACS. Conclusion. Increased number of dust storms resulted in a higher prevalence of mortality due to ACS while mortality due to heart failure remained unchanged. Admission, hospitalization, and mortality due to chest pain both dependent and independent of ACS were increased by the presence of dust storms, PM10 elevation, and maximum temperature.

Highlighting Exosomes' Function in Cardiovascular Diseases

2021 ◽  
Vol 17 ◽  
Author(s):  
Sidhi Laksono ◽  
Budhi Setianto ◽  
Ananta Siddhi Prawara ◽  
Bambang Dwiputra
Keyword(s):  
Myocardial Infarction ◽  
Heart Failure ◽  
Heart Disease ◽  
Cardiovascular Diseases ◽  
Prognostic Marker ◽  
Therapeutic Agent ◽  
Diagnostic Marker ◽  
Cell Communication ◽  
Surface Protein ◽  
Cardiovascular Patients

: Exosomes as one of the extracellular vesicles’ subgroups played an important role in the cell to cell communication. The cargos and surface protein of exosomes have been known to affect the cardiovascular system both positively and negatively in chronic heart failure, ischemic heart disease, and atherosclerosis. There have been several exosomes that emerged as a potential diagnostic and prognostic marker in cardiovascular patients. However, the conditions affecting the patients and the method of isolation should be considered to create a standardized normal value of the exosomes and the components. CPC-derived exosomes, ADSCs-derived exosomes, and telocyte-derived exosomes have been proven to be capable ofacting as a therapeutic agent in myocardial infarction models. Exosomes have the potential to become a diagnostic marker, prognostic marker, and therapeutic agent in cardiovascular diseases.

Prevention of atrial fibrillation – non-modifiable and modifiable risk factors for AF

2020 ◽  
Vol 2 (55) ◽  
pp. 14-19
Author(s):  
Agnieszka Wojdyła-Hordyńska ◽  
Grzegorz Hordyński
Keyword(s):  
Risk Factors ◽  
Heart Failure ◽  
Atrial Fibrillation ◽  
Cardiovascular Disease ◽  
Cardiovascular Diseases ◽  
Sudden Cardiac Death ◽  
Cardiac Death ◽  
Combined Treatment ◽  
Lifestyle Changes ◽  
Modifiable Risk Factors

Atrial fibrillation is one of the most common arrhythmias, with a significant increase in incidence in recent years. AF is a major cause of stroke, heart failure, sudden cardiac death, and cardiovascular disease. Timely intervention and modification of risk factors increase chance to stop the disease. Aggressive, multilevel prevention tactics are a component of combined treatment, including – in addition to lifestyle changes, anticoagulant therapy, pharmacotherapy and invasive anti-arrhythmic treatment – prevention of cardiovascular diseases, hypertension, ischemia, valvular disease and heart failure.

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