scholarly journals GC-MS EXAMINATION OF METHANOLIC FLOWER EXTRACT OF Cirsium arvense

2021 ◽  
Vol 27 (2) ◽  
pp. 173-180
Author(s):  
Malik Fiaz Hussain Ferdosi ◽  
Iqra Haider Khan ◽  
Arshad Javaid ◽  
Muhammad Faraz Ahmad Fardosi
Keyword(s):  
Carbonic Acid ◽  
Methanolic Extract ◽  
Literature Survey ◽  
Cirsium Arvense ◽  
Anticancer Activities ◽  
Flower Extract ◽  
Ms Analysis

Cirsium arvense (L.) Scop., commonly known as creeping thistle, is a weed of Asteraceae. This study was undertaken to explore various phytoconstituents present in flower of this weed. To achieve this goal, the dried flowers of this weed were soaked in methanol for one week and filtered. This methanolic extract was subjected to GC-MS analysis and 7 compounds were identified. These included olean-12-en-3-ol, acetate, (3β)- (63.87%), lanosta-8,24-dien-3-ol, acetate, (3β)- (12.12%), β-amyrin (6.19%), γ-sitosterol (6.09%), α-amyrin (5.24%), stigmasterol (3.29%) and carbonic acid, 2-ethylhexyl heptadecyl ester (3.16%). Literature survey showed that these compounds possess anti-inflamatory, antimicrobial, antidiabetic, antioxidant and/or anticancer activities.

GC-MS ANALYSIS OF PHYTOCHEMICALS IN THE METHANOLIC EXTRACT OF Caesalpinia coriaria (Jacq) Willd.

2016 ◽  
Vol 4 (7) ◽  
pp. 1417-1422 ◽  
Author(s):  
P.T. Srinivasan ◽  
◽  
D. Anandhi ◽  
S. Kanimozhi ◽  
M. Anbarasan. ◽  
...  
Keyword(s):  
Methanolic Extract ◽  
Ms Analysis

Neuroprotective Activity of the Methanolic Extract of Indigofera aspalathoides against Scopalamine induced Alzheimer's Disease in Experimental Rats

2021 ◽  
pp. 5163-5168
Author(s):  
Rajaram C. ◽  
S. Nelson Kumar ◽  
S. S. Sheeba Tabassum ◽  
Manohar R. ◽  
Sumanjali C.
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Traditional Medicine ◽  
Methanolic Extract ◽  
Therapeutic Potential ◽  
Neuroprotective Effect ◽  
Neuroprotective Activity ◽  
Control Group ◽  
Histological Structure ◽  
Anticancer Activities

The plant Indigofera aspalathoides is a traditional medicine with tremendous therapeutic potential which finds it use in treatment of various ailments such as antibacterial, antioxidant, anti-inflammatory, antidiabetic, and anticancer activities. There are no reports that related to the use of this plant in treating patients with Alzheimer’s disease (AD). Hence present study was aimed to scientifically evaluate the neuroprotective effect of the methanolic extract of Indigofera aspalathoides against scopalamine induced Alzheimer’s disease in experimental rats using behavioral tests like elevated plus maze, Y-maze, and rota-rod tests. In addition to this, biochemical evaluation for acetylcholinesterase activity and histopathological evaluation of brain were done. The results suggests that methanolic extract Indigofera aspalathoides (200mg/kg B.wt and 400mg/kg B.wt) used in this study shows significant improvement of various behavioral parameters like locomotion, anxiety, memory, motor integrity and coordination etc when compared to control group. MEIA inhibited brain AChE enzyme, thereby elevating Ach concentration in brain homogenate and ultimately improved memory of rats. Further, more or less normal histological structure of the hippocampus and all amyloid plaques and neurofibrillary tangles that are formed under the influence of scopolamine disappeared in the rats pretreated with MEIA (200mg/kg B.wt and 400mg/kg B.wt). It can be concluded that our results strongly support the anti-Alzheimer’s potential of the methanolic extract of the plant I.aspalathoides and its use in traditional medicine.

scholarly journals Anticancer Activities of the Methanolic Extract from Lemon Leaves in Human Breast Cancer Stem Cells

2015 ◽  
Vol 58 (3) ◽  
pp. 219-226 ◽  
Author(s):  
Jeong Yong Moon ◽  
Linh Thi Thao Nguyen ◽  
Ho Bong Hyun ◽  
Ahmed Osman ◽  
Minwhan Cho ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Stem Cells ◽  
Cancer Stem Cells ◽  
Human Breast Cancer ◽  
Methanolic Extract ◽  
Breast Cancer Stem Cells ◽  
Human Breast ◽  
Anticancer Activities

scholarly journals UPLC-HRESI-MS and GC-MS analysis of the leaves of Nicotiana glauca

2021 ◽  
Vol 72 (1) ◽  
pp. 97-108
Author(s):  
Rafeef K. Massadeh ◽  
Tamam El-Elimat ◽  
Mohammad Al-Gharaibeh ◽  
Khaled Tawaha ◽  
Feras Q. Alali
Keyword(s):  
High Resolution ◽  
Plant Material ◽  
Methanolic Extract ◽  
Volatile Oil ◽  
Ethyl Linoleate ◽  
Major Constituent ◽  
Hexadecanoic Acid ◽  
Nicotiana Glauca ◽  
Plant Oil ◽  
Ms Analysis

Abstract The alkaloid-rich fraction obtained by fractionation of the crude methanolic extract of the leaves of wild tobacco tree Nicotiana glauca Graham (Solanaceae) was analyzed using UPLC-MS and GC-MS. Anabasine, a piperidine alkaloid, was identified as the major constituent with approximately 60 % (m/m) of the alkaloid-rich fraction. In addition to anabasine, six secondary metabolites were identified using high-resolution UPLC-MS. Anabasine was quantified in the leaves to be 1 mg g−1 dry plant material. The GC-MS analysis revealed five compounds with anabasine as the major component, while nicotine was not detected. Moreover, GC-MS was used for the analysis of the volatile oil that was obtained by hydro-distillation from the leaves of N. glauca. The volatile plant oil was found to be rich in oxygenated sesquiterpenes (e.g., β-bisabolol) and carboxylic acids and esters (e.g., ethyl linoleate and hexadecanoic acid), whereas anabasine was not detected.

scholarly journals “Pharmaco-chemical Characterization and Evaluation of In Vitro Antioxidant and Antidiabetic Activity of Ethanolic Flower Extract of Clerodendrum paniculatum”

2020 ◽  
Vol 11 (3) ◽  
pp. 4569-4577
Author(s):  
Sincy Varghese ◽  
Kanakasabapathi Devaki ◽  
Poornima Kannappan ◽  
Sri Rashmy Madathil
Keyword(s):  
Secondary Metabolites ◽  
Plant Material ◽  
Quantitative Estimation ◽  
Chemical Characterization ◽  
Antidiabetic Activity ◽  
Flower Extract ◽  
Ms Analysis ◽  
Ic50 Value ◽  
Biochemical Features

Quantitative and qualitative analysis of different components and antioxidant and activities of the extract of flower (CPF) were analyzed in . identification of of flower was also identified by GC-MS analysis. assess the biochemical features of CPF. solvent extraction of CPF was performed using solvents in increasing order of polarity (petroleum ether, chloroform, ethyl acetate, ethanol, and water) and solvent with maximum profile was standardized for further analysis. Quantitative analysis of selected secondary metabolites like tannin, , alkaloids, and of the flower extract was done by UV . In antioxidant assays and in efficacy of the flower extract were analyzed by respective in assays. identification of in CPF was identified by using GC-MS analysis revealed secondary metabolites in the extract, and further analysis of the extract was performed. Quantitative estimation revealed an accountable amount of secondary metabolites like (47.66mg/g acid equivalent), (24mg/g equivalent), (41mg/g equivalent), and alkaloids (1.79mg/g of extracted plant material). analysis (GC-MS) also confirmed convincing compounds in the extract. From in antioxidant and assay, the IC50 value of the extract of CPF was measured and compared with standard, and from the results, it was evident that the extract had significant in antioxidant and activity. the above results, it can be confirmed thatCPF has got significant and therapeutically active ingredients, as evident in analysis. This is further supported by considerable antioxidant and properties observed in respective assays.

Eugenol Found by GC-MS Analysis of The Methanolic Extract of The Fruit Pulp of Indigenous Mango (Mangifera indica L.) Variety, Champa from Murshidabad District of West Bengal, India

2021 ◽  
Vol 4 (1) ◽  
Author(s):  
Mitu De ◽  
Susanta Ray ◽  
Subhasree Dutta ◽  
Santi Ranjan Dey
Keyword(s):  
Volatile Compounds ◽  
West Bengal ◽  
Methanolic Extract ◽  
Mangifera Indica ◽  
Fruit Pulp ◽  
Ms Analysis ◽  
Bioactive Component ◽  
Herbal Plants ◽  
Michelia Champaca

Indigenous mango (Mangifera indica L.) varieties have unique aroma, taste, flavour, texture and size. The interactions among volatile compounds and with sugars and acids have a role in the distinct mango flavor. Murshidabad district of West Bengal has several indigenous mango varieties that have unique attributes like taste and aroma. The indigenous Champa mango variety of Murshidabad district has a distinct aroma very similar to that of the champaka flower (Michelia champaca L.). The present investigation was to determine if there was any phyto-chemical which could be responsible for the distinct and unique aroma present in the mango variety Champa. Eugenol, a phytogenic bioactive component frequently found in diversified herbal plants was found by GC-MS analysis of the methanolic extract of the fruit pulp of indigenous mango variety, Champa.

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