scholarly journals FAKTOR RISKO PENYAKIT DIABETES TIPE II DI DAERAH PEDESAAN LITERATURE REVIEW

2021 ◽  
Vol 8 (3) ◽  
pp. 102
Author(s):  
Dona Prima Fierda ◽  
Febianti Rahayu ◽  
Ghina Roudhatul Jannah ◽  
Dwi Sarwani Sri Rejeki
Keyword(s):  
Diabetes Mellitus ◽  
United States ◽  
Risk Factors ◽  
Literature Review ◽  
Rural Area ◽  
Google Scholar

Saat ini semakin banyak dijumpai penderita DM tipe II di pedesaan sehingga masyarakat di pedesaan membutuhkan pengetahuan tentang faktor risiko DM tipe II. Penelitian ini bertujuan menganalisis artikel ilmiah yang berhubungan dengan faktor risiko DM tipe II di daerah pedesaan. Desain yang digunakan yaitu literature review. Artikel berbahasa Indonesia maupun Inggris dengan rentang waktu 2016-2021, kriteria inklusi yang memuat data-data penelitian yang berhubungan dengan kata kunci serta kriteria eksklusi yang tidak berhubungan dengan topik seperti diabetes mellitus di daerah perkotaan. Data didapat dari database meliputi ScienceDirect, PubMed, dan Google Scholar dengan kata kunci risk factors, diabetes mellitus, rural area. Faktor risiko penyakit diabetes mellitus tipe II di daerah pedesaan yaitu wanita dengan usia rata-rata 55 tahun, tingkat pendidikan rendah, kurangnya aktivitas fisik, dan pola makan buruk yang dapat menyebabkan obesitas dengan IMT >25. Dari 6 negara yaitu Indonesia, India, China, United States, Brazil, Tanzania dan Uganda, diperoleh faktor risiko dominan yang mempengaruhi kejadian DM tipe II yaitu kurangnya aktivitas fisik. Pendidikan di pedesaan cenderung rendah sehingga meningkatkan risiko DM tipe II. Dari hasil tersebut didapatkan kesimpulan faktor risiko penyakit diabetes mellitus tipe II di daerah pedesaan antara lain usia, jenis kelamin, aktivitas fisik, pola makan, dan tingkat pendidikan, sehingga diperlukan peran serta masyarakat dan pemerintah dalam menekan angka kejadian diabetes mellitus di pedesaan.

scholarly journals Faktor Risiko Terjadinya Coronavirus Disease 2019 (Covid-19) pada Penyandang Diabetes Melitus Tipe 2

e-CliniC ◽  
2021 ◽  
Vol 9 (1) ◽  
Author(s):  
Pomantow A. L. Roeroe ◽  
Bisuk P. Sedli ◽  
Octavianus Umboh
Keyword(s):  
Diabetes Mellitus ◽  
Risk Factors ◽  
Literature Review ◽  
Blood Glucose Control ◽  
Google Scholar ◽  
Elderly Age ◽  
Coagulation Activity ◽  
Review Study ◽  
Diabetes Melitus

Abstract: Coronavirus Disease 2019 (COVID-19) is an infectious disease caused by SARS-CoV-2 and has been declared as a pandemic by WHO in March 11, 2020. This disease is an additional problem in people with type 2 diabetes mellitus (T2DM). Several studies have shown that diabetes is a risk factor for COVID-19. This study was aimed to determine the risk factors for the occurrence of Coronavirus Disease 2019 (COVID-19) in T2DM patients. This was a literature review study using several journal databases, namely Google Scholar, PubMed, and Science Direct. Literature searching was performed by using the PICOS method and the analysis was carried out qualitatively The results obtained 10 literatures reporting that T2DM would increase the severity and mortality of COVID-19 patients related to elderly age, obesity, chronic systemic inflammation, increased coagulation activity, potential direct damage to the pancreas, changes in expression of ACE2 receptors, dysregulation of the number, activity of immune cells, alveolar dysfunction, and endothelial dysfunction. There was not yet strong evidence regarding discontinuation or continuation of various diabetes drugs in COVID-19 patients, but insulin remains the recommended agent for blood glucose control. In conclusion, T2DM increases the severity and mortality rate of COVID-19 patients Keywords: diabetes mellitus; COVID-19; risk factors Abstrak: Coronavirus Disease 2019 (COVID-19) merupakan salah satu penyakit infeksi yang disebabkan oleh SARS-CoV-2 dan telah ditetapkan sebagai pandemi oleh WHO pada 11 Maret 2020. Penyakit ini menjadi masalah tambahan bagi penyandang diabetes melitus tipe 2 (DMT2). Beberapa penelitian menunjukkan bahwa diabetes merupakan salah satu faktor risiko terjadinya COVID-19. Penelitian ini bertujuan untuk mengetahui faktor risiko terjadinya COVID-19 pada penyandang DMT2. Jenis penelitian ialah literature review menggunakan laporan penelitian dari beberapa database jurnal, yaitu google scholar, PubMed, dan ClinicalKey. Pencarian artikel menggunakan metode PICOS dan analisis dilakukan secara kualitatif. Hasil penelitian mendapatkan 10 laporan penelitian yang melaporkan bahwa DMT2 meningkatkan tingkat keparahan dan mortalitas pasien COVID-19 akibat adanya mekanisme terkait dengan usia lanjut, obesitas, peradangan sistemik kronis, peningkatan aktivitas koagulasi, potensi kerusakan langsung pankreas, perubahan ekspresi reseptor ACE2, disregulasi jumlah dan aktivitas sel imun, disfungsi alveolar, dan disfungsi endotel. Belum terdapat bukti kuat mengenai penghentian atau pelanjutan berbagai obat diabetes pada pasien COVID-19, tetapi insulin tetap menjadi obat yang disarankan untuk mengontrol glukosa darah. Simpulan penelitian ini ialah DMT2 meningkatkan tingkat keparahan dan mortalitas dari pasien COVID-19.Kata kunci: diabetes melitus tipe 2 (DMT2), COVID-19, faktor risiko

scholarly journals Gaya Hidup sebagai Faktor Risiko Diabetes Melitus Tipe 2

e-CliniC ◽  
2021 ◽  
Vol 9 (2) ◽  
pp. 328
Author(s):  
Made K. Murtiningsih ◽  
Karel Pandelaki ◽  
Bisuk P. Sedli
Keyword(s):  
Physical Activity ◽  
Diabetes Mellitus ◽  
Risk Factors ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Literature Review ◽  
Google Scholar ◽  
Eating Pattern ◽  
Diabetes Melitus

Abstract: Type 2 diabetes mellitus (T2DM) is a metabolic disease caused by insulin resistance and beta cell dysfunction. It is ranked as the seventh of top 10 causes of death worldwide, and the highest prevalence of cases is T2DM. The dominant lifestyle that triggers T2DM is diet and physical inactivity. This study was aimed to determine whether lifestyle was a risk factor of T2DM. This was a literature review study using two databases, namely Pubmed and Google Scholar. The keywords used were "lifestyle risk factors and type 2 diabetes mellitus". There were 10 literatures obtained based on inclusion and exclusion criteria. The results showed that lifestyle such as unhealthy eating pattern and less physical activity significantly influence the risk factors of T2DM. In conclusion, lifestyles such as unhealthy foods and less physical activity are at high risk of suffering from T2DM.Keywords: risk factors, lifestyle, type 2 diabetes mellitus (T2DM)  Abstrak: Diabetes melitus tipe 2 (DMT2) merupakan penyakit metabolisme yang disebabkan karena resistensi insulin dan disfungsi sel beta pankreas. DM berada diperingkat ke tujuh sebagai 10 penyakit penyebab kematian di dunia, denganDMT2 sebagai prevalensi kasus tertinggi. Pola hidup yang dominan menjadi pencetus DMT2 ialah pola makan dan aktivitas fisik. Penelitian ini bertujuan untuk mengetahui gaya hidup sebagai faktor risiko DMT2. Jenis penelitian ialah literature review. Pencarian data menggunakan dua database yaitu Pubmed dan Google Scholar. Dengan kata kunci yaitu “faktor risiko gaya hidup dan diabetes melitus tipe 2”. Setelah diseleksi, didapatkan 10 literatur berdasarkan kriteria inklusi dan eksklusi. Hasil penelitian mendapatkan bahwa gaya hidup seperti pola makan yang tidak sehat dan pola aktivitas fisik kurang secara bermakna berpengaruh terhadap terjadinya faktor risiko DMT2. Simpulan penelitian ini ialah gaya hidup dengan mengonsumsi makanan tidak sehat dan aktivitas fisik yang kurang memiliki risiko tinggi mengalami DMT2.Kata kunci: faktor risiko, gaya hidup, diabetes melitus tipe 2 (DMT2)

scholarly journals Pneumonia Covid-19 dengan Gangguan Ginjal Akut

e-CliniC ◽  
2021 ◽  
Vol 9 (1) ◽  
Author(s):  
Rivaldy Wahab ◽  
Efata Poli ◽  
Cerelia Sugeng
Keyword(s):  
Diabetes Mellitus ◽  
Risk Factors ◽  
Acute Kidney Injury ◽  
Mortality Rate ◽  
Literature Review ◽  
Kidney Injury ◽  
Google Scholar ◽  
Nephrotoxic Drugs ◽  
Review Study ◽  
Diabetes Melitus

Abstract: SARS-CoV-2 infection causes various symptoms, including mild, moderate, severe, and critical symptoms. Severe SARS-CoV-2 infection can cause pneumonia, acute respiratory syndrome, kidney failure, and even death. This study was aimed to evaluate patients with COVID-19 pneumonia associated with acute kidney injury (AKI). This was a literature review study using three databases, namely PubMed, ClinicalKey, and Google Scholar. The keywords used were acute kidney injury AND pneumonia AND COVID-19. The results showed 10 selected literatures based on inclusion and exclusion criteria. All literatures stated that males dominated the study samples (52.4-73%). The risk factors of AKI in COVID-19 pneumonia were co-morbidities which were predominantly hypertension, diabetes mellitus, COPD, cardiovascular diseases, and respiratory diseases, as well as nephrotoxic drugs. AKI was the complication of pneumonia COVID-19. The mortality rate was higher among pneumonia COVID-19 patients with AKI compared to pneumonia COVID-19 patients without AKI. In conclusion, AKI is the complication of COVID-19 pneumonia. Nephrotoxic drugs and co-morbidities are the risk factors of AKI in COVID-19 pneumonia.  The mortality rate is higher in patients with AKI compared to those without AKI.Keywords: acute kidney injury, pneumonia COVID-19, coronavirus disease 2019  Abstrak: Infeksi SARS-CoV-2 menimbulkan berbagai gejala baik yang ringan, sedang, berat        hingga kritis. Infeksi SARS-CoV-2 yang berat dapat menyebabkan pneumonia, sindrom pernapasan akut, gagal ginjal, bahkan kematian. Penelitian ini bertujuan untuk mengetahui gambaran pneumonia COVID-19 dengan gangguan ginjal akut (GGA). Jenis penelitian ialah literature review dengan pencarian data menggunakan tiga database yaitu PubMed, ClinicalKey, dan Google Scholar. Kata kunci yang digunakan ialah acute kidney injury AND pneumonia AND COVID-19. Hasil penelitian mendapatkan 10 literatur berdasarkan kriteria inklusi dan eksklusi. Pada semua literatur didapatkan jenis kelamin laki-laki yang mendominasi sampel penelitian (52,4-73%). Riwayat penyakit didominasi oleh hipertensi, diabetes melitus, PPOK, penyakit kardiovaskuler, dan penyakit pernapasan. GGA merupakan komplikasi pada pneumonia COVID-19. Pasien pneumonia COVID-19 dengan gangguan ginjal akut memiliki angka kematian yang lebih tinggi dibandingkan dengan pasien pneumonia COVID-19 tanpa gangguan ginjal akut di rumah sakit. Faktor risiko gangguan ginjal akut pada pneumonia COVID-19, antara lain: penggunaan obat yang bersifat nefrotoksik, memiliki komorbid (usia tua, diabetes mellitus, penyakit kardiovaskular, penyakit ginjal kronis, dll). Sinpulan penelitian ini ialah GGA merupakan komplikasi pada pneumonia COVID-19. Penggunaan obat yang bersifat nefrotoksik dan adanya komorbid merupakan faktor risiko terjadinya GGA pada pasien pneumonia COVID-19. Angka kematian lebih tinggi terdapat pada pasien pneumonia COVID-19 dengan GGA dibandingkan dengan yang tanpa GGA.kata kunci: gangguan ginjal akut, pneumonia COVID-19, coronavirus disease 2019

Hubungan Dukungan Keluarga Dengan Kadar Gula Darah Pada Pasien Diabetes Mellitus Tipe 2: Literature Review

2021 ◽  
Vol 1 ◽  
pp. 309-316
Author(s):  
Nurul Febrian Bintari Putri ◽  
Trina Kurniawati
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Literature Review ◽  
Family Support ◽  
Blood Sugar ◽  
Google Scholar ◽  
The Family ◽  
Sugar Levels

AbstractDiabetes mellitus is a chronic disease that cannot be cured, but can be prevented by using the 5 pillars of diabetes mellitus management, one of which is controlling blood sugar levels. Patients with diabetes mellitus need support from the family because the family can influence a person's behavior and lifestyle so that it has an impact on the quality of life of patients with type 2 diabetes mellitus. To determine the relationship between family support and blood sugar levels in patients with type 2 diabetes mellitus through a literature review. The data collection technique uses a literature review method of 5 articles sourced from an online database with electronic searches on Google Scholar, Garba Garuda, and ProQuest published in 2017-2021. The critical analysis instrument used is using a strobe. The results of a literature review on the family support variable were 2 articles with supporting categories as many as 128 respondents, 2 articles with less categories as many as 63 respondents, and 1 article with good categories as many as 22 respondents. Variable blood sugar levels 2 articles in the controlled category as many as 98 respondents, 1 article in the poor category as many as 45 respondents, 1 article in the controlled category as many as 17 respondents, and 1 article in the diabetes category as many as 29 respondents. There is a relationship between family support and blood sugar levels in patients with type 2 diabetes mellitus.Keywords: Type 2 diabetes mellitus; family support; blood glucose levels; blood sugar levels AbstrakDiabetes mellitus merupakan penyakit kronik yang tidak dapat disembuhkan, namun dapat dicegah dengan menggunakan 5 pilarpengelolaan diabetes mellitus, salah satunya pengendalian kadar gula darah. Pasien diabetes mellitus perlu adanya dukungan dari keluarga karena keluarga dapat mempengaruhi perilaku dan gaya hidup seseorang sehingga berdampak pada kualitas hidup pasien diabetes mellitus tipe 2. Untuk mengetahui hubungan dukungan keluarga dengan kadar gula darah pada pasien diabetes mellitus tipe 2 melalui literature review. Teknik pengumpulan data menggunakan metode literature review 5 artikel yang bersumber database online dengan penelusuran elektronik pada Google Scholar, Garba Garuda, dan ProQuest yang dipublish pada tahun 2017-2021. Instrumen telaah kritis yang digunakan yaitu menggunakan Strobe. Hasil literature review pada variable dukungan keluarga 2 artikel dengan kategori mendukung sebanyak 128 responden, 2 artikel dengan kategori kurang sebanyak 63 responden, dan 1 artikel dengan kategori baik sebanyak 22 responden. Variable kadar gula darah 2 artikel dengan kategori terkendali sebanyak 98 responden, 1 artikel dengan kategori buruk sebanyak 45 responden, 1 artikel dengan kategori terkontrol sebanyak 17 responden, dan 1 artikel dengan kategori diabetes sebanyak 29 responden. Terdapat hubungan antara dukungan keluarga dengan kadar gula darah pada pasien diabetes mellitus tipe 2.Kata kunci: Diabetes mellitus tipe 2;dukungan keluarga;kadar glukosa darah;kadar gula darah

Abstract 237: Prevalence of Cardiovascular Risk Factors and Cardiovascular Disease in Transgender Persons in The United States

2020 ◽  
Vol 13 (Suppl_1) ◽  
Author(s):  
Aditi Malhotra ◽  
Hal A Skopicki ◽  
Smadar Kort ◽  
Noelle Mann ◽  
Puja Parikh
Keyword(s):  
Diabetes Mellitus ◽  
United States ◽  
Risk Factors ◽  
Cardiovascular Disease ◽  
Chronic Obstructive Pulmonary Disease ◽  
Chronic Kidney Disease ◽  
The United States ◽  
Chronic Obstructive ◽  
Obstructive Pulmonary Disease ◽  
Transgender Persons

Background: There is a paucity of data regarding prevalence of cardiovascular disease (CVD) and corresponding cardiovascular (CV) risk factors in transgender individuals. We sought to assess the prevalence of CV risk factors and CVD in transgender persons in the United States. Methods: The 2018 Centers for Disease Control’s Behavioral Risk Factor Surveillance Survey was utilized to identify a cohort of 1,038 transgender individuals in the United States. Presence of CVD was noted with a single affirmative response to the following questions: “Has a health care professional ever told you that you had any of the following:” (1) a heart attack or myocardial infarction, (2) angina or coronary heart disease, (3) a stroke? Results: Among the 1,038 transgender individuals studied, a total of 145 (14.0%) had CVD while 893 (86.0%) did not. No differences in prevalence of CVD was noted in transgender individuals who transitioned from male-to-female (n=387), female-to-male (n=400), and gender nonconforming status (n=251) (15.0% vs 13.8% vs 12.7%, p=0.72). Transgender individuals with CVD were older, had lower annual income, higher rates of smoking (28.4% vs 18.1%, p=0.004), and higher rates of multiple co-morbidities including asthma (26.6% vs 17.4%, p = 0.009), skin cancer (21.8% vs 5.0%, p <0.001), non-skin cancers (16.8% vs 6.8%, p <0.001), chronic obstructive pulmonary disease (27.5% vs 7.0%, p <0.001), arthritis (65.3% vs 28.7%, p<0.001), depressive disorder (42.7% vs 31.0%, p= 0.006), chronic kidney disease (16.2% vs 3.3%, p< 0.001), and diabetes mellitus (42.0% vs 12.7%, p <0.001). No significant differences in race, health insurance status, or body mass index was noted between transgender individuals with CVD versus those without. In multivariable analysis, independent predictors of CVD in transgender individuals included older age, diabetes mellitus [odds ratio (OR) 2.82, 95% confidence interval (CI) 1.73 - 4.58], chronic kidney disease (OR 3.69, 95% CI 1.80 - 7.57), chronic obstructive pulmonary disease (OR 2.18, 95% CI 1.19 - 3.99), and depressive disorder (OR 1.82, 95% CI 1.09 - 3.03). Conclusions: In this observational contemporary study, CVD was prevalent in 14% of transgender individuals in the United States. Predictors of CVD in the transgender population exist and transgender persons should be appropriately screened for CV risk factors so as to minimize their risk of CVD.

scholarly journals 765. Pyomyositis in the United States: Trends and Associations From the Healthcare Utilization Project Nationwide Inpatient Sample Database

2019 ◽  
Vol 6 (Supplement_2) ◽  
pp. S340-S341
Author(s):  
Rheanne K Maravelas ◽  
Thomas Melgar ◽  
Sapna Sadarangani ◽  
Neiberg Lima ◽  
Zachary Rich ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
United States ◽  
Risk Factors ◽  
Healthcare Utilization ◽  
Nationwide Inpatient Sample ◽  
Myositis Ossificans ◽  
Organ Transplant ◽  
The United States ◽  
Nationwide Inpatient Sample Database ◽  
Duration Of Hospitalization

Abstract Background Pyomyositis is a spontaneous infection of skeletal muscle that can lead to abscess formation and sepsis. The purpose of our study was to better describe the characteristics, risk factors, and trends of primary pyomyositis in the United States. Methods This study is a retrospective review of data from the Healthcare Utilization Project Nationwide Inpatient Sample Database from 2002 to 2014. We systematically searched ICD-9 codes and included diagnoses of infective myositis and/or tropical pyomyositis and excluded progressive myositis ossificans and/or traumatic myositis ossificans. We compiled lists of codes for co-occurring infections, candidate risk factors, and microbiological data. Each group of related ICD-9 codes was combined into a single composite indicator. SAS studio was utilized for analysis. Results The database included a total of 100,790,900 discharges accounting for 482,872,274 weighted discharges with 13,011 pyomyositis cases accounting for 62,657 weighted cases. The patients with pyomyositis were significantly more likely to be younger, male, and have a longer duration of hospitalization. The proportion of discharges with pyomyositis has steadily risen more than 3-fold from 0.0054% to 0.0209%. Of the cases of pyomyositis, a minority had co-occurring deep tissue infections: 16.9% had osteomyelitis and 8.8% had septic arthritis. We found significantly higher rates of co-occurrence with HIV, diabetes mellitus, organ transplant, alcohol abuse, and chronic kidney disease compared with the general hospitalized population, suggesting these as relevant risk factors. When microorganisms were diagnosed, Staphylococus aureus was most common, followed by Streptococcus spp. Conclusion Our study identified a rapid increase in pyomyositis cases in the United States over our 12-year study period. Our results substantiate risk factors for pyomyositis related to immunosuppression and suggest that diabetes mellitus may be an important risk factor in the United States. Identifying causative organisms is helpful for empiric treatment. It is important that clinicians be aware of this emerging diagnosis relevant in both temperate and tropical areas of the globe. Disclosures All authors: No reported disclosures.

scholarly journals Aging and Disability Among Hispanics in the United States: Current Knowledge and Future Directions

2017 ◽  
Vol 1 (2) ◽  
Author(s):  
Marc A Garcia ◽  
Brian Downer ◽  
Michael Crowe ◽  
Kyriakos S Markides
Keyword(s):  
United States ◽  
Risk Factors ◽  
Life Expectancy ◽  
Literature Review ◽  
Old Age ◽  
Current Knowledge ◽  
The United States ◽  
Life Course Perspective ◽  
Future Research ◽  
Minority Population

Abstract Background and Objectives Hispanics are the most rapidly aging minority population in the United States. Our objective is to provide a summary of current knowledge regarding disability among Hispanics, and to propose an agenda for future research. Research Design and Methods A literature review was conducted to identify major areas of research. A life course perspective and the Hispanic Paradox were used as frameworks for the literature review and for identifying future areas of research. Results Four research areas were identified: (1) Ethnic disparities in disability; (2) Heterogeneity of the U.S. older Hispanic population; (3) Risk factors for disability; and (4) Disabled life expectancy. Older Hispanics are more likely than non-Hispanic whites to be disabled or to become disabled. Disability varied by country of origin, nativity, age of migration, and duration in the United States. Important risk factors for disability included chronic health conditions, depression, and cognitive impairment. Protective factors included positive affect and physical activity. Older Hispanics have longer life expectancy than non-Hispanic whites but spend a greater proportion of old age disabled. Future research should continue to monitor trends in disability as younger generations of Hispanics reach old age. Attention needs to be given to regional variation within the United States for disability prevalence, early-life risk factors, and factors that may contribute to variation in disabled life expectancy. There is also an urgent need for interventions that can effectively prevent or delay the onset of disability in older Hispanics. Discussion and Implications Considerable research has examined disability among older Hispanics, but continued research is needed. It is important that research findings be used to inform public policies that can address the burden of disability for older Hispanic populations.

scholarly journals FAKTOR RISIKO HIPOGLIKEMIA PADA DIABETES MELLITUS: LITERATURE RIVIEW

2020 ◽  
Vol 2 (2) ◽  
pp. 20-29
Author(s):  
Heri Budiawan ◽  
Hikmat Permana ◽  
Etika Emaliyawati
Keyword(s):  
Diabetes Mellitus ◽  
Risk Factor ◽  
Literature Review ◽  
Google Scholar

Pendahuluan : Identifikasi faktor-faktor yang berhubungan dengan kejadian hipoglikemia penting dilakukan untuk mengetahui faktor resiko kejadian hipoglikemia, sehingga dapat digunakan sebagai dasar acuan pencegahan hipoglikemia berat dan hipoglikemia berulang. Objektif : Bertujuan untuk melakukan Literature review mengenai faktor-faktor yang berhubungan dengan kejadian hipoglikemia pada pasien diabetes mellitus. Metode : Metode penelusuran sumber data pada Literature review ini yaitu melakukan penulusuran database terdiri dari Google Scholar, Pubmed, Ebsco dengan kata kunci yang digunakan untuk pencarian pada databased Internasioanal yang pertama yaitu “Diabetes mellitus” AND “Risk factor hypoglycemia” “OR” Predictor hypoglycemia” Sedangkan pada databased Nasional menggunakan kata kunci yang pertama yaitu “Diabetes Mellitus “ dan” Faktor resiko hipoglikemia.”. Artikel diseleksi berdasarkan kriteria inklusi dan melakukan critical apraisel pada setiap artikel. Hasil : Berdasarkan hasil pencarian ditetapkan 8 artikel dengan design Kuantitatif publikasi 10 tahun terakhir (2009-2019). Faktor resiko yang berkaitan dengan kejadian hipoglikemia pada pasien diabetes mellitus yaitu terapi insulin, sulfolinurea, dan terapi kombinasi merupakan prediktor kuat terjadinya hipoglikemia, namun ada beberapa faktor lain yang berkaitan dengan kejadian hipoglikemia diantaranya nilai HbA1c, BMI,  usia, jenis kealmin, pekerjaan, tingkat pendidikan, lama menderita diabetes mellitus, penyakit penyerta (penyakit ginjal kronis), dukungan keluarga, dan gaya hidup (konsumsi alcohol). Kesimpulan: Faktor resiko kejadian hipoglikemia pada pasien diabetes mellitus berkaitan dengan faktor medikasi (pemberian insulin, sulfolinurea, terapi kombinasi) dan faktor demografi pasien, oleh karena itu pengkajian resiko hipoglikemia pada pasien diabetes mellitus penting untuk diketahui, sehingga dapat berpotensi mencegah kejadian atau menurunkan kejadian hipoglikemi dan dapat meningkatkan kualitas hidup pasien diabetes mellitus

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