scholarly journals Optimal waist circumference cut-off points and prediabetic state as predictors of metabolic syndrome prevalence among Saudi adults in Jeddah city

2021 ◽  
Vol 7 (2) ◽  
pp. 072-084
Author(s):  
Bashaer O Alhejaili ◽  
Rajaa M Al-Raddadi ◽  
Suhad M Bahijri ◽  
Al-Mutairi khalid Dakhil Allah ◽  
Salma Mohammed Yehya Suhluli ◽  
...  
Keyword(s):  
Metabolic Syndrome ◽  
Waist Circumference ◽  
High Educational Level ◽  
Prediabetic State ◽  
Cross Sectional ◽  
Jeddah City ◽  
The Metabolic Syndrome ◽  
Primary Health Care Centers ◽  
Health Care Centers ◽  
High Educational

With increasing prevalence of metabolic syndrome and absence of local waist circumference cut-off point, it is important to determine the local cut-off point of waist circumference to predict metabolic syndrome. The aim of this study is to estimate the prevalence of metabolic syndrome among Saudi adults who attend primary health care centers (PHC) in Jeddah city in 2017, and to determine the appropriate waist circumference cut-off value for identifying a person at risk for the metabolic syndrome. A cross-sectional analytic study was conducted. Results shows; mean age of participants was 30.94±9.70 and waist circumference was 96.87±17.40 in males and 86.51±15.30 in females. The prevalence (CI: 95%) of pre-diabetes was 16.3% (12.9%; 20.1%), while the prevalence of metabolic syndrome was {(95% CI = 10.6%) (7.80%; 13.8%)}. Abdominal obesity was the most frequent component of MetS, detected in 60.6%, and followed by high blood pressure in 25.0%. In males, a waist circumference≥93.5 cm is likely to indicate MetS with 100% sensitivity and 47.2% specificity; whereas, in females, optimal waist circumference cut-off was determined as ≥83.5 cm, showing 92.3% sensitivity and 46.4% specificity. In multivariate logistic regression, extended waist circumference was the strongest predictor of MetS {OR (95%CI) =3.75 (1.30; 10.81); p=0.014}, followed by the presence pre-diabetes {OR (95%CI) =2.31 (1.06; 5.04); p=0.035}. Further, high educational level was a significant predictor for MetS {OR (95%CI) = 0.34 (0.12; 0.99); p=0.047}; while age and marital status were not significant predictors.

scholarly journals Isotemporal substitution of inactive time with physical activity and time in bed: cross-sectional associations with cardiometabolic health in the PREDIMED-Plus study

2019 ◽  
Vol 16 (1) ◽  
Author(s):  
Aina M. Galmes-Panades ◽  
Veronica Varela-Mato ◽  
Jadwiga Konieczna ◽  
Julia Wärnberg ◽  
Miguel Ángel Martínez-González ◽  
...  
Keyword(s):  
Physical Activity ◽  
Blood Pressure ◽  
Older Adults ◽  
Metabolic Syndrome ◽  
Body Composition ◽  
Waist Circumference ◽  
Biochemical Parameters ◽  
Cross Sectional ◽  
The Metabolic Syndrome ◽  
Time In Bed

Abstract Background This study explored the association between inactive time and measures of adiposity, clinical parameters, obesity, type 2 diabetes and metabolic syndrome components. It further examined the impact of reallocating inactive time to time in bed, light physical activity (LPA) or moderate-to-vigorous physical activity (MVPA) on cardio-metabolic risk factors, including measures of adiposity and body composition, biochemical parameters and blood pressure in older adults. Methods This is a cross-sectional analysis of baseline data from 2189 Caucasian men and women (age 55–75 years, BMI 27–40 Kg/m2) from the PREDIMED-Plus study (http://www.predimedplus.com/). All participants had ≥3 components of the metabolic syndrome. Inactive time, physical activity and time in bed were objectively determined using triaxial accelerometers GENEActiv during 7 days (ActivInsights Ltd., Kimbolton, United Kingdom). Multiple adjusted linear and logistic regression models were used. Isotemporal substitution regression modelling was performed to assess the relationship of replacing the amount of time spent in one activity for another, on each outcome, including measures of adiposity and body composition, biochemical parameters and blood pressure in older adults. Results Inactive time was associated with indicators of obesity and the metabolic syndrome. Reallocating 30 min per day of inactive time to 30 min per day of time in bed was associated with lower BMI, waist circumference and glycated hemoglobin (HbA1c) (all p-values < 0.05). Reallocating 30 min per day of inactive time with 30 min per day of LPA or MVPA was associated with lower BMI, waist circumference, total fat, visceral adipose tissue, HbA1c, glucose, triglycerides, and higher body muscle mass and HDL cholesterol (all p-values < 0.05). Conclusions Inactive time was associated with a poor cardio-metabolic profile. Isotemporal substitution of inactive time with MVPA and LPA or time in bed could have beneficial impact on cardio-metabolic health. Trial registration The trial was registered at the International Standard Randomized Controlled Trial (ISRCTN: http://www.isrctn.com/ISRCTN89898870) with number 89898870 and registration date of 24 July 2014, retrospectively registered.

scholarly journals The prevalence of metabolic syndrome and its association with body fat distribution in middle-aged individuals from Indonesia and the Netherlands: a cross-sectional analysis of two population-based studies

2020 ◽  
Vol 12 (1) ◽  
Author(s):  
Fathimah S. Sigit ◽  
Dicky L. Tahapary ◽  
Stella Trompet ◽  
Erliyani Sartono ◽  
Ko Willems van Dijk ◽  
...  
Keyword(s):  
Metabolic Syndrome ◽  
Waist Circumference ◽  
The Netherlands ◽  
Abdominal Obesity ◽  
Dutch Population ◽  
Middle Aged ◽  
Cross Sectional ◽  
Metabolic Complications ◽  
Men And Women ◽  
The Metabolic Syndrome

Abstract Background The prevalence of metabolic syndrome varies among populations with different ethnicities. Asian populations develop metabolic complications at lower amounts of adiposity than western populations. The role of abdominal obesity in the metabolic differences between the two populations is poorly understood. Objectives Our objectives were to estimate the prevalence of metabolic syndrome and the relative contribution of its components in the Indonesian and the Dutch population, as well as to examine the associations of overall and abdominal obesity with metabolic syndrome. Methods In this cross-sectional study of middle-aged adults in the Netherlands Epidemiology of Obesity Study (n = 6602) and the Indonesian National Health Surveillance (n = 10,575), metabolic syndrome was defined by the unified IDF and AHA/NHLBI criteria. We performed logistic and linear regressions to examine associations of BMI and waist circumference with the metabolic syndrome, mutually adjusted for waist circumference and BMI. Results The prevalence of metabolic syndrome was 28% and 46% in Indonesian men and women, and 36% and 24% in Dutch men and women. The most prominent components were hypertension (61%) and hyperglycemia (51%) in the Indonesian, and hypertension (62%) and abdominal obesity (40%) in the Dutch population. Per SD in BMI and waist circumference, odds ratios (ORs, 95% CI) of metabolic syndrome were 1.5 (1.3–1.8) and 2.3 (1.9–2.7) in Indonesian men and 1.7 (1.2–2.5) and 2.9 (2.1–4.1) in Dutch men. The ORs of metabolic syndrome were 1.4 (1.2–1.6) and 2.3 (2.0–2.7) in Indonesian women and 1.0 (0.8–1.3) and 4.2 (3.2–5.4) in Dutch women. Conclusion More Indonesian women than men have metabolic syndrome, whereas the opposite is true for the Dutch population. In both the Indonesian and the Dutch populations, hypertension is the primary contributor to the prevalence of metabolic syndrome. In both populations, abdominal adiposity was more strongly associated with metabolic syndrome than overall adiposity.

scholarly journals Association of 25(OH)D and PTH with Metabolic Syndrome and Its Traditional and Nontraditional Components

2011 ◽  
Vol 96 (1) ◽  
pp. 168-175 ◽  
Author(s):  
Sheena Kayaniyil ◽  
Reinhold Vieth ◽  
Stewart B. Harris ◽  
Ravi Retnakaran ◽  
Julia A. Knight ◽  
...  
Keyword(s):  
Metabolic Syndrome ◽  
Vitamin D ◽  
Waist Circumference ◽  
Density Lipoprotein ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
Supplement Use ◽  
The Metabolic Syndrome ◽  
Multivariate Adjustment ◽  
25 Hydroxy Vitamin D

Context: Emerging evidence suggests that 25-hydroxy vitamin D [25(OH)D] and PTH may play a role in the etiology of the metabolic syndrome (MetS). However, evidence to date is limited and inconsistent, and few studies have examined associations with nontraditional MetS components. Objective: The objective of the study was to examine the association of vitamin D and PTH with MetS and its traditional and nontraditional components in a large multiethnic sample. Design, Setting, and Participants: In this cross-sectional study, we examined 654 participants from London and Toronto, Ontario, Canada, aged 30 yr and older with risk factors for type 2 diabetes. Main Outcome Measures: Presence of MetS and its traditional and nontraditional components was measured. Results: Approximately 43% of the study participants were classified as having MetS. Higher 25(OH)D was significantly associated with a reduced presence of MetS after adjustment for age, sex, season, ethnicity, supplement use, physical activity, and PTH (odds ratio 0.76, 95% confidence interval 0.62–0.93). PTH was not associated with the presence of MetS after multivariate adjustment. Multivariate linear regression analyses indicated significant adjusted inverse associations of 25(OH)D with waist circumference, triglyceride level, fasting insulin, and alanine transaminase (P &lt; 0.041). Elevated PTH was positively associated with waist circumference and high-density lipoprotein cholesterol (P &lt; 0.04). Other associations between PTH and MetS components were attenuated after adjustment for adiposity. Conclusions: Serum 25(OH)D, but not PTH, was significantly associated with MetS as well as a number of MetS components after multivariate adjustment. These results suggest that low 25(OH)D may play a role in the etiology of the MetS.

scholarly journals Metabolic syndrome in haemodialysis patients: Prevalence, determinants and association to cardiovascular outcomes

2020 ◽  
Author(s):  
Arnaud Delautre ◽  
François Chantrel ◽  
Yves Dimitrov ◽  
Alexandre Klein ◽  
Olivier Imhoff ◽  
...  
Keyword(s):  
Metabolic Syndrome ◽  
Waist Circumference ◽  
Visceral Obesity ◽  
Density Lipoprotein ◽  
Roc Curves ◽  
Major Adverse Cardiovascular Events ◽  
Operating Characteristics ◽  
Clinical Predictors ◽  
Cross Sectional ◽  
The Metabolic Syndrome

Abstract Background In the general population, the metabolic syndrome (MetS) has been identified as predictive of major adverse cardiovascular events (MACE). Waist circumference (WC), a component of the MetS criteria, is linked to visceral obesity, which in turn is correlated with MACE. However, in haemodialysis (HD) patients, the association between MetS, WC and MACE is unclear.Methods In a cross-sectional study of 1000 HD patients, we evaluated the prevalence and characterised the clinical predictors of MetS. The relationship between MetS and its components, alone or in combination, and MACE, as defined by comorbidity among coronary diseases, peripheral arteriopathy, stroke or cardiac failure, was further studied using receiver operating characteristics (ROC) curves and logistic regression.Results A total of 753 patients were included between October 2011 and April 2013. The prevalence of MetS was 68.5%. Waist circumference (> 88 cm in women, 102 cm in men) was the best predictor of MetS (sensitivity 80.2; specificity 82.3; AUC 0.80; p < 0.05). In multivariate analysis, MetS was associated with MACE (OR: 1.85; 95CI 1.24-2.75; p < 0.01), but not WC alone. There was a stronger association between the combination of abdominal obesity, hypertriglyceridaemia and low high-density lipoprotein cholesterol with MACE after exclusion of impaired fasting glucose and hypertension.ConclusionsMetS is frequent and associated with MACE in HD patients in our region and probably in other European dialysis populations. In HD patients, a new simplified definition could be proposed, in keeping with the concept of hypertriglyceridaemic waist.

scholarly journals Gender and Age-Related Differences in Patients with the Metabolic Syndrome in A Highly Endogamous Population.

2010 ◽  
Vol 10 (3) ◽  
pp. 210-217 ◽  
Author(s):  
Abdulbari Bener ◽  
Abdul-Ghani Mohammad ◽  
Asia N. Ismail ◽  
Mahmoud Zirie ◽  
Waleed K. Abdullatef ◽  
...  
Keyword(s):  
Metabolic Syndrome ◽  
International Diabetes Federation ◽  
Developed Countries ◽  
Cross Sectional Study ◽  
Age Group ◽  
Cross Sectional ◽  
The Metabolic Syndrome ◽  
Age Related ◽  
Gender And Age ◽  
Primary Health Care Centers

The objective of the study was to examine the differences in gender and age prevalences of metabolic syndrome (MetS) among adult Qatari population according to the revised criteria of NCEP ATP III and IDF, assess which component contributed to the higher prevalence of the MetS and identify the characteristics of the subjects with MetS. The study was designed as a cross-sectional study. The survey was carried out in urban and semi-urban primary health care centers. The survey was conducted in the period from January 2007 to July 2008 among Qatari nationals above 20 years of age. Of the 1536 subjects who were approached to particípate in the study, 1222 (79.6%) gave their consent. Face to face interviews were conducted using a structured questionnaire followed by laboratory tests. MetS was defined using the National Cholesterol Education Program - Third Adult Treatment Panel (ATP III) as well as the International Diabetes Federation (IDF). The overall prevalence of MetS in studied subjects was 26.7% and 33.9% according to ATPIII and IDF (p<0.001) criteria respectively. The prevalence of MetS by both definitions peaked in the 30-39 years age group among males, and the 40-49 years age group among females. The greatest number of males with MetS were university educated; while the greatest number of females with MetS were either illiterate or had a primary school education. The prevalence of MetS was higher among females. Among the components of MetS, the prevalence of central obesity was significantly higher in studied subjects. The overall prevalence of MetS and its components according to IDF criteria was higher in studied subjects than the estimates given by the ATPIII criteria. Overall, the prevalence of the metabolic syndrome in the State of Qatar is about 10-15% higher than in most developed countries, with generally higher prevalence rates for women. Preventive strategies will require identifying socio-demographic factors and addressing modifiable risk behaviours, including lack of physical activity, and dietary intake.

scholarly journals HUBUNGAN ANTARA LINGKAR PINGGANGDENGANKADARHS-CRP SERUMPADA MAHASISWA OBES DAN TIDAK OBES DI FAKULTAS KEDOKTERAN UNIVERSITAS SAM RATULANGI MANADO

2014 ◽  
Vol 2 (1) ◽  
Author(s):  
Anita Ohe S. Fatie ◽  
Alexander S. L. Bolang ◽  
Nelly Mayulu
Keyword(s):  
Metabolic Syndrome ◽  
Waist Circumference ◽  
Sedentary Lifestyle ◽  
Developed Countries ◽  
Cross Sectional ◽  
The Past ◽  
The Metabolic Syndrome ◽  
Inflammatory Stimuli ◽  
Important Health ◽  
Hs Crp

Abstract: The rapid socioeconomic growth has led to a more sedentary lifestyle and change in diet over the past several decades. As a result of prosperity,obesity has become an important health problem. And then problem healthnutrition world, both in developed countries and in developing countries. Waist circumference more than normal is one component in the metabolic syndrome. An increased incidence of metabolic syndrome in line with the increase in obesity. Hs-CRP is a protein in the synthesis in the liver in response to inflammatory stimuli during the acute phase. This research was conducted to find out the waist circumference and hs-CRP levels in students faculty of medicine University of Sam Ratulangi Manado. And the type of research used is the observational approach cross sectional analytic. Results anasis statistics by using test mann whitney u showed there are different meaning ( p = 0.00 ( 0,00 ). Based on the test spearmen statistics then obtained value a correlation coefficient ( r ) by 0.472 and value ρ = 0.000 < α= 0.05.. This shows there is a relationship between waist circumference with hs-CRP levels on students obese and not obese in medical schools university sam ratulangi manado. Keyword: waist circumference, hs-CRP   Abstrak: Percepatan pertumbuhan sosial ekonomi menyebabkan orang lebih kurang bergerak dimana perubahan dalam pola diet dan yang terjadi pada beberapa dekade. Akibatnya obesitas menjadi masalah penting bagi kesehatan. Dan jugamasalah  kesehatan    gizimasyarakatdunia, baikdinegaramajumaupundinegara berkembang. Lingkar Pinggang yang besar dari normal adalah salah satu komponen dalam sindroma metabolik. Peningkatan kejadian sindroma metabolik sejalan dengan peningkatan obesitas.Hs-CRP merupakan protein yang di sintesis di hati sebagai respon terhadap rangsangan pada saat inflamasi fase akut.Penelitian ini dilakukan untuk mengetahui Lingkar Pinggang dan kadar hs-CRP pada Mahasiswa Fakultas Kedokteran Universitas Sam Ratulangi Manado. Dan jenis penelitian yang dipakai adalah observasional analitik dengan pendekatan cross sectional. Hasil anasis statistik dengan menggunakan uji Mann Whitney U menunjukan terdapat perbedan bermakna (p=0.00(0,00). Berdasarkan hasil uji spearmen statistik maka didapatkan nilai koefisien korelasi (r) sebesar 0.472 dan nilai ρ = 0.000 < α= 0.05. Hal ini menunjukan terdapat hubungan antara lingkar pinggang dengan kadar  hs-CRP pada mahasiswa obes dan tidak obes di Fakultas Kedokteran Universitas Sam Ratulangi Manado. Kata Kunci: Lingkar Pinggang, hs-CRP

scholarly journals Evaluation of Metabolic Syndrome among Locomotive Drivers

2020 ◽  
Author(s):  
M Saraei ◽  
A Najafi ◽  
E Heidarbagi ◽  
A Rahimi-Golkhandan
Keyword(s):  
Risk Factors ◽  
Blood Pressure ◽  
Metabolic Syndrome ◽  
Waist Circumference ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
High Waist Circumference ◽  
The Metabolic Syndrome ◽  
High Prevalence ◽  
Train Drivers

Introduction: Screening of risk factors for metabolic syndrome among commercial and train drivers that are considered safety sensitive jobs, is an important issue in safety of transportation system. Metabolic syndrome is consisted of disturbed lipid profile, high blood pressure, and high waist circumference. It can lead to decrease the quality of life and higher health associated costs for these patients. This study aimed to assess risk factors for metabolic syndrome among train drivers. Methods: This cross-sectional study was conducted on 281 train drivers referred to their annual health examinations to Occupational Medicine Clinic of Baharloo Hospital, Tehran University of Medical Sciences. Demographic characteristics of participants were recorded. Blood pressure, body mass index and waist circumference of drivers were measured. Participants’ blood sample for fasting blood sugar, triglyceride, high and low density lipoproteins were collected. Metabolic syndrome was defined according to the NCEP ATP III criteria. Results: All of the participants were males.  Their mean age and BMI was 43±10 year and 26.60±3.67 Kg/m2, respectively. Fifty three (21%) of the participants were diagnosed with metabolic syndrome. The more frequent risk factor for metabolic syndrome was triglyceride more than 150mg/dl. Conclusion: Findings of the present study revealed high prevalence of metabolic syndrome among train drivers. Further studies are needed for screening the metabolic syndrome in this occupational group as it is a sensitive occupation.

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