scholarly journals ETHOLOGY OF THE TREMATODE CERCARIAE SCHISTOSOMA TURKESTANICA SKRJABIN, 1913, WHEN EMITTED FROM NATURALLY INVASIVE LYMNAEA AURICULARIAL MOLLUSKS, 1758

2019 ◽  
pp. 371-378 ◽  
Author(s):  
Moskvin
Keyword(s):  
Circulatory System ◽  
The Body ◽  
Intermediate Hosts ◽  
Surface Layers ◽  
Two Phase ◽  
Original Algorithm ◽  
Central Asian ◽  
Inside Out ◽  
Vertical Mobility

The characteristics of ethnological characteristics of cercaria trematodes Schistosoma turkestanica Skrjabin, 1913 are detailed with emission from naturally invasive intermediate hosts, Lymnaea auricularia mollusks L., 1758.The modern correct species name of the dioecious trematodes of the Schistosomatidae family, the parasitic circulatory system of cattle in the Central Asian region, should be considered Schistosoma turkestanica Skrjabin, 1913.Spontaneous emission of furcocercarium Sch. turkestanica from invasive L. auricularia, can occur in various parts of the mollusk's body surface. The process of the release of the larva into the environment proceeds according to the original algorithm, accompanied by its morpho- functional adaptations, taking 15–17 seconds. The active initial transient phase of piercing “from inside-out” in the first 2–3 seconds is ensured by the body of the larva, which is drawn in length, taking the shape of a needle. Then, the tail of the cercaria is released from the puncture site. Tissue damage in the area of release of the larvae was not visually marked.Fourcocarii Sch. turkestanica have positive photo– and negative geotaxis, which modulate continuous two-phase, mainly vertical mobility, ensuring their long-term stay in the plankton state in the surface layers of water. Features of cervary ethology increase the likelihood of targeted active contact and the effectiveness of the attack of definitive hosts of the trematodes.

scholarly journals Morphobiological characteristics of trematode cercariae of the families Opisthorchiidae and Notocotylidae

2020 ◽  
Vol 49 (6) ◽  
pp. 71-78
Author(s):  
О. M. Bonina ◽  
Е. А. Serbina
Keyword(s):  
Life Cycle ◽  
Western Siberia ◽  
The Body ◽  
Parasitic Diseases ◽  
Body Structure ◽  
Intermediate Hosts ◽  
Laboratory Conditions ◽  
Bithynia Tentaculata ◽  
Morphobiological Characteristics

The results of studying the body structure of trematode cercariae of the families Opisthorchiidae and Notocotylidae and the features of their development in Western Siberia are presented. The data of long-term (1994–2019) studies on the spread of these pathogens of dangerous parasitic diseases in humans and animals are analyzed and summarized. The studies were conducted according to generally accepted methods in parasitology and hydrobiology. The species affi  liation of trematodes was determined in laboratory conditions on mature cercariae that independently left the shells of the host mollusks Bithynia tentaculata and B. troscheli. It was noted that the trematodes of the Opisthorchiidae and Notocotylidae families at the cercaria stage have the following similar features: a simple tail, pigmented eyes, and one oral sucking cup. Diagnosis of trematode cercariae of Opisthorchiidae and Notocotylidae families is possible by the following signs: the tail of the opisthorchis cercaria has a swimming membrane and is 2 times longer than the body, the tail of the notocotylid has no swimming membrane and is approximately equal in length to the body. Opisthor-chis cercariae have two pigment eyes, notocotilids – three. In the life cycle of opisthorchis, there are two intermediate hosts (bitinia and fi  sh), in the notocotylid cycle, one (bitinia). Opisthorchis cercariae have penetration glands, but notocotylids do not; the maximum daily emission of opisthorchis cercariae is ten times higher than that of notocotylids (6672 and 422 cercariae, respectively). The ability to diagnose opisthorchis and notocotilid at the cercaria stage allows the identifi cation of local foci of epidemiologically and epizootically dangerous diseases.

The evolution of water-breathing respiratory faculties in invertebrates

2019 ◽  
pp. 109-112
Author(s):  
Steven F. Perry ◽  
Markus Lambertz ◽  
Anke Schmitz
Keyword(s):  
Circulatory System ◽  
Bilateral Symmetry ◽  
The Body ◽  
Phylogenetic Position ◽  
Control Element ◽  
Term Survival ◽  
Respiratory Proteins ◽  
Evolutionary Story ◽  
Internal Transport

This chapter aims at piecing together the evolution of water breathing in invertebrates. Dedicated respiratory faculties, consisting of an external exchanger, an internal transport system (circulatory system or an equivalent), and some control element are first clearly recognizable among invertebrates in annelids, which excel in the number of different respiratory proteins they display. Molluscs and arthropods use primarily haemocyanin, each group showing evolutionary trends in respiratory proteins that have some bearing on the phylogenetic position. Each major group of molluscs has its own evolutionary story, but in general we see a reduction in the number of gills and often a release from bilateral symmetry. Among arthropods, crustaceans can develop gills on various parts of the legs and the body wall, each group showing a taxon-specific type. Arachnids and hexapods are primarily terrestrial, but several groups have independently and secondarily developed mechanisms for even long-term survival under water.

Defining the Competence of Psychologists with a View to Public Accountability *

1997 ◽  
Vol 2 (4) ◽  
pp. 293-300 ◽  
Author(s):  
Ype H. Poortinga ◽  
Ingrid Lunt
Keyword(s):  
Scientific Knowledge ◽  
Professional Training ◽  
Professional Competence ◽  
Codes Of Ethics ◽  
The Body ◽  
The European Union ◽  
Rigorous Evaluation ◽  
Judicial Proceedings ◽  
Psychological Knowledge

In national codes of ethics the practice of psychology is presented as rooted in scientific knowledge, professional skills, and experience. However, it is not self-evident that the body of scientific knowledge in psychology provides an adequate basis for current professional practice. Professional training and experience are seen as necessary for the application of psychological knowledge, but they appear insufficient to defend the soundness of one's practices when challenged in judicial proceedings of a kind that may be faced by psychologists in the European Union in the not too distant future. In seeking to define the basis for the professional competence of psychologists, this article recommends taking a position of modesty concerning the scope and effectiveness of psychological interventions. In many circumstances, psychologists can only provide partial advice, narrowing down the range of possible courses of action more by eliminating unpromising ones than by pointing out the most correct or most favorable one. By emphasizing rigorous evaluation, the profession should gain in accountability and, in the long term, in respectability.

STUDIES IN THE SUPPOSED GOITROGENOUS EFFECT OF TAP WATER IN HELSINKI

1960 ◽  
Vol XXXIII (IV) ◽  
pp. 630-636
Author(s):  
F.-E. Krusius ◽  
P. Peltola
Keyword(s):  
Tap Water ◽  
Physiological Saline ◽  
Normal Weight ◽  
The Body ◽  
Iodine Uptake ◽  
Redistilled Water ◽  
Detectable Difference ◽  
Term Administration ◽  
Long Term Experiment

ABSTRACT The study reported here was performed in order to examine the tap water of Helsinki for its alleged goitrogenous effect. In a short-term, 24-hour experiment with rats, kept on an iodine-poor diet, we noticed no inhibition of the 4-hour 131I uptake, as compared with that of animals receiving physiological saline instead of tap water. Two similar groups of rats receiving 1 and 2 mg of mercazole in redistilled water showed a distinct blockage of the 4-hour uptake, which proved the effect of this substance. In a long-term experiment of 5 weeks' duration there was no detectable difference in the body weight, thyroid weight and the 4-hour 131I uptake when the rats receiving tap water or distilled water to which 0.45 per cent of sodium chloride was added were compared with each other. Replacement of tap water by a 10 mg per cent solution of mercazole in redistilled water enlarged the thyroid to double its normal weight and increased the 131I uptake to approximately five times that of the controls. Thus our experiments failed to demonstrate any goitrogenous effect in the tap water of Helsinki. Changes similar to those produced by a long-term administration of mercazole, i. e. an enlargement of the thyroid and an increased thyroidal iodine uptake, have been shown to be due to milk collected from goitrous areas. The observations here reported confirm the importance of milk in the genesis of the goitre endemia of Helsinki. Attention is further called to the fact that a thyroidal enlargement combined with an increased thyroidal iodine uptake cannot always be taken as a sign of iodine deficiency because similar changes may be produced by the administration of goitrogens.

Long-term Efficacy and Safety of Brodalumab in Patients With Psoriasis Disease Duration <10 and ≥10 Years: Analysis of Two Phase 3 Studies

2019 ◽  
Vol 3 ◽  
pp. S25
Author(s):  
Benjamin Ehst ◽  
George Han ◽  
Scott Guenthner ◽  
Kimberly Eads ◽  
Abby Jacobson
Keyword(s):  
Disease Duration ◽  
Efficacy And Safety ◽  
Phase 3 ◽  
Two Phase ◽  
Term Efficacy

Abstract not available.

ANALYSIS OF ABDOMINAL TYPHOID INCIDENCE IN THE SOUTH REGION OF THE KYRGYZ REPUBLIC

2020 ◽  
pp. 43-48
Author(s):  
Zakirova J.S. ◽  
Nadirbekova R.A. ◽  
Zholdoshev S.T.
Keyword(s):  
Drinking Water ◽  
Typhoid Fever ◽  
Risk Groups ◽  
The Body ◽  
Kyrgyz Republic ◽  
Radiation Factor ◽  
High Quality ◽  
Two Generations ◽  
Immunological Deficiency

The article analyze the long-term morbidity, spread of typhoid fever in the southern regions of the Kyrgyz republic, and remains a permanent epidemic focus in the Jalal-Abad region, where against the low availability of the population to high-quality drinking water, an additional factor on the body for more than two generations and radiation factor, which we confirmed by the spread among the inhabitants of Mailuu-Suu of nosological forms of the syndrome of immunological deficiency, as a predictor of risk groups for infectious diseases, including typhoid fever.

Comparative assessment of morphological mechanisms of maintaining structural liver homeostasis in the dynamics of exposure to coal-rock dust and sodium fluoride on the body

2020 ◽  
pp. 189-194
Author(s):  
M. S. Bugaeva ◽  
O. I. Bondarev ◽  
N. N. Mikhailova ◽  
L. G. Gorokhova
Keyword(s):  
Sodium Fluoride ◽  
Morphological Changes ◽  
The Body ◽  
System Level ◽  
Production Factor ◽  
Coal Rock ◽  
The Impact ◽  
Structural Homeostasis ◽  
Rock Dust

Introduction. The impact on the body of such factors of the production environment as coal-rock dust and fluorine compounds leads to certain shift s in strict indicators of homeostasis at the system level. Maintaining the relative constancy of the internal environment of the body is provided by the functional consistency of all organs and systems, the leading of which is the liver. Organ repair plays a crucial role in restoring the structure of genetic material and maintaining normal cell viability. When this mechanism is damaged, the compensatory capabilities of the organ are disrupted, homeostasis is disrupted at the cellular and organizational levels, and the development of the main pathological processes is noted.The aim of the study is to compare the morphological mechanisms of maintaining structural homeostasis of the liver in the dynamics of the impact on the body of coal-rock dust and sodium fluoride.Materials and methods. Experimental studies were conducted on adult white male laboratory rats. Features of morphological mechanisms for maintaining structural homeostasis of the liver in the dynamics of exposure to coal-rock dust and sodium fluoride were studied on experimental models of pneumoconiosis and fluoride intoxication. For histological examination in experimental animals, liver sampling was performed after 1, 3, 6, 9, 12 weeks of the experiment.Results. The specificity of morphological changes in the liver depending on the harmful production factor was revealed. It is shown that chronic exposure to coal-rock dust and sodium fluoride is characterized by the development of similar morphological changes in the liver and its vessels from the predominance of the initial compensatory-adaptive to pronounced violations of the stromal and parenchymal components. Long-term inhalation of coal-rock dust at 1–3 weeks of seeding triggers adaptive mechanisms in the liver in the form of increased functional activity of cells, formation of double-core hepatocytes, activation of immunocompetent cells and endotheliocytes, ensuring the preservation of the parenchyma and the general morphostructure of the organ until the 12th week of the experiment. Exposure to sodium fluoride leads to early disruption of liver compensatory mechanisms and the development of dystrophic changes in the parenchyma with the formation of necrosis foci as early as the 6th week of the experiment.Conclusions. The study of mechanisms for compensating the liver structure in conditions of long-term exposure to coal-rock dust and sodium fluoride, as well as processes that indicate their failure, and the timing of their occurrence, is of theoretical and practical importance for developing recommendations for the timely prevention and correction of pathological conditions developing in employees of the aluminum and coal industry.The authors declare no conflict of interests.

Immunological mechanisms of chronic liver lesions under the influence of chemicals

2020 ◽  
pp. 536-537
Author(s):  
G. S. Agzamova ◽  
M. M. Abdullaeva
Keyword(s):  
The Body ◽  
Chronic Liver ◽  
Toxic Substances ◽  
Liver Lesions ◽  
Industrial Chemicals ◽  
Toxic Agent ◽  
Chronic Poisoning ◽  
Immunological Mechanisms ◽  
T System

The immunological profile of chronic liver lesions depending on the toxic agent was studied. It was revealed that chronic poisoning by industrial toxic substances causes changes in the functional state of the T-system of immunity, long-term contact with industrial chemicals leads to increased sensitization to autoantigens of the body.

Neurophysiological and morphological effects in the post-exposure vibration period during experimental modeling

2019 ◽  
pp. 284-290
Author(s):  
Natalya L. Yakimova ◽  
Vladimir A. Pankov ◽  
Aleksandr V. Lizarev ◽  
Viktor S. Rukavishnikov ◽  
Marina V. Kuleshova ◽  
...  
Keyword(s):  
Nervous System ◽  
Evoked Potentials ◽  
Experimental Model ◽  
Visual Evoked Potentials ◽  
The Body ◽  
Behavioral Activity ◽  
Contact Period ◽  
Vibration Exposure ◽  
Visual Evoked

Introduction. Vibration disease continues to occupy one of the leading places in the structure of professional pathology. In workers after the termination of contact with vibration generalization and progression of violations in an organism is noted. The pathogenetic mechanisms of the progredient course of disturbances in the nervous system in the post-contact period of vibration exposure remain insufficiently studied.The aim of the study was to test an experimental model of vibration exposure to assess the neurophysiological and morphological effects of vibration in rats in the dynamics of the post-contact period.Materials and methods. The work was performed on 168 white male outbred rats aged 3 months weighing 180–260 g. The vibration effect was carried out on a 40 Hz vibrating table for 60 days 5 times a week for 4 hours a day. Examination of animals was performed after the end of the physical factor, on the 30th, 60th and 120th day of the post-contact period. To assess the long-term neurophysiological and morphofunctional effects of vibration in rats, we used indicators of behavioral reactions, bioelectric activity of the somatosensory zone of the cerebral cortex, somatosensory and visual evoked potentials, parameters of muscle response, morphological parameters of nervous tissue.Results. In the dynamics of the post-contact period observed the preservation of violations of tentatively research, motor and emotional components of behavior. In the Central nervous system instability of activity of rhythms of an electroencephalogram, decrease in amplitude of visual evoked potentials, lengthening of latency of somatosensory evoked potentials, decrease in total number of normal neurons and astroglia is established. In the peripheral nervous system remained changes in indicators: increasing duration and latency, reducing the amplitude of the neuromuscular response.Conclusions: The experimental model allows us to study the long-term neurophysiological and morphological effects of vibration on the body. The formation and preservation of changes in behavioral activity, neurophysiological and morphological effects of vibration from the 30th to the 120th day of the post-contact period were confirmed.

Unmaking and Remaking the World in Long-Term Solitary Confinement

2018 ◽  
Vol 1 (1) ◽  
pp. 16
Author(s):  
Lisa Guenther
Keyword(s):  
The Body ◽  
Solitary Confinement ◽  
Hunger Strike ◽  
State Prison ◽  
Legal Documents ◽  
The Social ◽  
The World ◽  
Collective Resistance ◽  
Civil Death

In The Body in Pain, Elaine Scarry analyzes the structure of torture as an unmaking of the world in which the tools that ought to support a person’s embodied capacities are used as weapons to break them down. The Security Housing Unit (SHU) of California’s Pelican Bay State Prison functions as a weaponized architecture of torture in precisely this sense; but in recent years, prisoners in the Pelican Bay Short Corridor have re-purposed this weaponized architecture as a tool for remaking the world through collective resistance. This resistance took the form of a hunger strike in which prisoners exposed themselves to the possibility of biological death in order to contest the social and civil death of solitary confinement. By collectively refusing food, and by articulating the meaning and motivation of this refusal in articles, interviews, artwork, and legal documents, prisoners reclaimed and expanded their perceptual, cognitive, and expressive capacities for world-making, even in a space of systematic torture.

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