scholarly journals Earthquake Relocation Studies near Local Scale Sources using Double-Difference Technique

2021 ◽  
Vol 1 (1) ◽  
pp. 394-398
Author(s):  
Wrego Seno Giamboro ◽  
Hafiz Hamdalah
Keyword(s):  
Seismic Energy ◽  
Mining Area ◽  
Underground Mines ◽  
Double Difference ◽  
Earthquake Relocation ◽  
Accuracy And Precision ◽  
Before And After ◽  
High Level ◽  
Mine Openings

Determination of the location of the hypocenter is very necessary to monitor the potential for seismic hazard. Positioning and seismic energy can help safety workers determine which areas can be mined or temporarily halted. Earthquakes in underground mines are caused by seismic induction due to mining activities such as blasting processes, hydrofracturing, vehicle activities, etc. Earthquakes that occur are generally clustering. Earthquake events generally occur in mine openings, this is caused by mass compensation taken. The data used in this study are synthetic micro-earthquake data around the mining area. To obtain a high level of accuracy and precision, especially in determining the location and depth in determining the hypocenter using the Double-Difference (DD) method. The results of the microseismic relocation in the study area are well covered, as evidenced by the residual histogram and shift distribution. The shift of the microseismic before and after being relocated spread in all directions with the dominant direction in the NE – SW direction. The value of the microseismic shift before and after being relocated ranged from 0.5 meters to 150 meters.

scholarly journals Effectiveness of reducing seismic hazard by means of group winning blasting - case study from a copper ore mine in Poland

2018 ◽  
Vol 66 ◽  
pp. 01010
Author(s):  
Anna Barbara Gogolewska ◽  
Natalia Czajkowska
Keyword(s):  
Seismic Event ◽  
Seismic Energy ◽  
Underground Mines ◽  
Copper Ore ◽  
Ore Deposit ◽  
South West ◽  
Effective Operation ◽  
Before And After

The copper ore deposit situated in the south-west of Poland is mined by three underground mines owned by KGHM Polish Copper JSC. Exploitation has been accompanied by rock burst hazard since the beginning. Thus, numerous different preventing measures have been developed such as temporary, organizational and long-term ones. However, no one has been able to predict the time, place and energy of a seismic event. The group winning blasting, with maximum number of blasted faces, is the most effective operation to reduce seismic threat. The more faces are blasted the more seismic energy should be reduced. The study aims at assessing the blasting effectiveness in inducing rock bursts and tremors. For this purpose, the seismic activity induced by mining and blasting were investigated. The number of blasting works and blasted faces as well as length of time between subsequent blasting works were analysed and related to provocation effectiveness. The linear correlation and different regressions were calculated to determine these relations. Moreover, the seismic energy reduction in the rock mass was evaluated by means of SRMS Index, which is a factor measured directly before and after blasting. The analyses covered one mine panel in the Polkowice-Sieroszowice copper mine over four-year period.

DETERMINATION OF PA INHIBITOR 1 (PA INHIBITOR ACTIVITY AND PA INHIBITOR 1 ANTIGEN) IN PLASMA BEFORE AND AFTER VENOUS OCCLUSION

1987 ◽  
Author(s):  
I Juhan-Vague ◽  
J Valadier ◽  
M C Alessi ◽  
J Ansaldi ◽  
M F Ailluad ◽  
...  
Keyword(s):  
Platelet Activation ◽  
Venous Occlusion ◽  
Inhibitor Activity ◽  
Post Surgery ◽  
In Vitro Activation ◽  
Before And After ◽  
High Level ◽  
Good Preparation

PA Inhibitor activity (PAIact-Verheijen’s method-U/ml) and PA Inhibitor 1 antigen (PAIlAg- Kruithof’s radioimmunoassay -ng/ml) were evaluated, on blood samples before (B) and after (A) venous occlusion (VO) (10 min) in order to analyse, in B-VO samples, the ratio (R=PAIlAg/PAIact) ' between the immunological and enzymatic material, and the change of PAIlAg levels after VO.The B-VO values (m ± SD) were determined from 111 plasmas : -86 with normal ( 12U/ml) PAIact levels = 3.7 ± 2.5 ; PAIlAg = 17.4 ± 10.1 ; R = 7.1 ± 6.2 (range 1.5 - 24 )-25 with high PAIact levels (15 post surgery, 10 obese patients)= 30.9± 19.3; PAIlAg = 75.3 ± 44.7 ; R = 2.7 ± 1.5 (range 1.3- 4.4). The correlation between the 2 dosages was r = 0.82 (p 0.01). In the 2 kinds of patients with high PAIact levels, a parallel high PAIlAg level was found. As the range of the ratio R was very large, patients were divided in 2 Groups : GrI : Normal R ( 7), n=81 (normal PAIact : n=57 ; high PAIact : n=24) and GrII : high R, n=30. The results for PAIact/PAIlAg/R were = GrI :12.6± 16.3/ 31.5±34.4/ 3.2 ± 1.5. GrII : 2.6±4.1/ 27.9 ±30.1/ 13.8±6.1. In GrII the platelet origin of inactive PAIlAg from in vitro activation of platelets could be demonstrated (high level of BTG lug/ml) in 50 % of cases. No in vitro platelet activation could be demonstrated in GrI. These results point out the necessity of a good preparation of the plasma (mainly 0-4°) for PAIlAg determination.The B and A-VO values were analysed from 60 subjects. Plasmas with in vitro activation of platelet determined by BTG levels had been discarded. No platelet activation occured with the VO. The results were not corrected with the PCV. PAIlAg B-VO/A-VO = 19.2 ± 15.1/ 26.9 ± 18.3. 36 subjects (60 % of total) had an increase in PAIlAg A-VO 20 % (mean increase = 62 %) . There was no correlation between basal values of PAIlAg and the increase after VO, and between PAIlAg increase and t-PA-Ag release. It is concluded that a weak increase of PAIlAg may occur after VO ; this increase is not parallel with t-PA release. The physiopathological significance of this increase of PAIlAg as yet to be evaluated.

The Plasmin Inhibitors of Plasma

1964 ◽  
Vol 12 (01) ◽  
pp. 119-125 ◽  
Author(s):  
Y Shamash ◽  
A Rimon
Keyword(s):  
Human Plasma ◽  
New Method ◽  
Normal Amount ◽  
Caseinolytic Activity ◽  
Before And After ◽  
Plasmin Inhibitors

SummaryA new method for the assay of plasmin inhibitors in human plasma is described. The method consists of determination of the caseinolytic activity of a standard plasmin solution before and after incubation with the inhibitor, with lysine added to the mixture as a stabilizer of plasmin. Using this method, it was found that plasma contains enough inhibitors to inactivate 30 caseinolytic units of plasmin, or 10 times the normal amount of plasminogen in human plasma.

FRACTIONAL DETERMINATIONS OF URINARY 17-KETOSTEROIDS IN HYPEREMESIS GRAVIDARUM

1962 ◽  
Vol 41 (1) ◽  
pp. 123-128 ◽  
Author(s):  
Pentti A. Järvinen ◽  
Sykkö Pesonen ◽  
Pirkko Väänänen
Keyword(s):  
Hyperemesis Gravidarum ◽  
First Trimester ◽  
Control Group ◽  
Before And After ◽  
Daily Urine ◽  
First Trimester Of Pregnancy ◽  
The Difference

ABSTRACT The fractional determination of 17-ketosteroids in the daily urine was performed in nine cases of hyperemesis gravidarum and in four control cases, in the first trimester of pregnancy both before and after corticotrophin administration. The excretion of total 17-KS is similar in the two groups. Only in the hyperemesis group does the excretion of total 17-KS increase significantly after corticotrophin administration. The fractional determination reveals no difference between the two groups of patients with regard to the values of the fractions U (unidentified 17-KS), A (androsterone) and Rest (11-oxygenated 17-KS). The excretion of dehydroepiandrosterone is significantly higher in the hyperemesis group than in the control group. The excretion of androstanolone seems to be lower in the hyperemesis group than in the control group, but the difference is not statistically significant. The differences in the correlation between dehydroepiandrosterone and androstanolone in the two groups is significant. The high excretion of dehydroepiandrosterone and low excretion of androstanolone in cases of hyperemesis gravidarum is a sign of adrenal dysfunction.

DETERMINATION OF BLOOD CORTICOIDS USING THE IN VITRO RESIN UPTAKE OF 3H-PREDNISOLONE

1968 ◽  
Vol 57 (1) ◽  
pp. 23-32 ◽  
Author(s):  
Hironori Nakajima ◽  
Mitsunori Murala ◽  
Masumitsu Nakata ◽  
Takeshi Naruse ◽  
Seiji Kubo
Keyword(s):  
Thyroid Function Test ◽  
Normal Subjects ◽  
Adrenal Function ◽  
Function Test ◽  
Before And After ◽  
Adrenal Response ◽  
Suppression Test

ABSTRACT The in vitro resin uptake of 3H-prednisolone was used for the determination of blood cortisol after addition of radioactive prednisolone followed by Amberlite CG 400 Type 1 to the test serum, and incubation of the mixture. The radioactivity of the supernatant was compared before and after the addition of the resin. The principle of this method is similar to that of the 131I-triiodothyronine resin uptake for the thyroid function test. The tests for the specificity, reproducibility and sensitivity gave satisfactory results. The mean basal value ± SD of the 3H-prednisolone resin uptake was 35.3 ± 9.2% in normal subjects, and 27.1 ± 4.8% in pregnant women. This method was valid in various adrenal function tests, i. e. the adrenal circadian rhythm, corticotrophin (ACTH) test, dexamethasone suppression test and the adrenal response to lysine-8-vasopressin. It proved to be a sensitive indicator of the adrenal function. These results suggest that this method should be useful for a routine adrenal function test.

Immediate implantation in a patient with chronic generalized parodontitis and apical granuloma

2019 ◽  
Vol 24 (2) ◽  
pp. 145-149
Author(s):  
A. I. Musienko ◽  
K. I. Nesterova
Keyword(s):  
Tooth Extraction ◽  
Tooth Root ◽  
Duration Of Treatment ◽  
Promising Direction ◽  
Aesthetic Result ◽  
Bone Atrophy ◽  
Alveolar Tissue ◽  
High Level ◽  
Immediate Implantation

Relevance. Rehabilitation of patients with moderate to severe generalized periodontitis is a leading problem in periodontology. It was the determination of the prospects for immediate implantation in patients with chronic periodontitis, combined with the pathology of the tooth root and maxillary sinus.Materials and methods. A group of 94 people with periodontitis and chronic odontogenic rhinosinus was observed who underwent sinus surgical treatment, tooth extraction and one-stage implantation with FRP growth factor according to the author's technology.Results. The method showed high efciency on the basis of assessing the clinical, aesthetic result and restoration of bone density after surgery.Conclusions. The developed technology is a promising direction, it allows to combine a high level of sanation of alveolar tissue with the advantages of immediate implantation, prevents bone atrophy, helps reduce the duration of treatment and the number of surgical and orthopedic interventions.

Methodical approaches to managing economic safety of tourism enterprises

2020 ◽  
pp. 160-164
Author(s):  
Leonid Tsubov ◽  
Oresta Shcherban
Keyword(s):  
Safety Management ◽  
Integrated Approach ◽  
Small Enterprise ◽  
Complex Nature ◽  
Efficient Management ◽  
Tourism Enterprises ◽  
High Level ◽  
Functional Components ◽  
Stimulation Control

The set of scientific-methodological tools to secure the mechanism of economic safety management of tourism entrepreneurship is examined as an aggregate of methods, tools, and conceptual activities directed at maintaining the high level of economic safety of tourism entrepreneurship. The features of managing the tourism enterprise and economic safety are analyzed. The basic valuation principles of the reliability and efficiency of the economic safety of the tourism enterprise are determined. The basic tasks of ensuring the economic safety of a small enterprise are outlined. The need to use the integrated approach that secures more opportunities to avoid threats and limits the danger of their emergence is emphasized. The most important principles for securing the economic safety of the tourism enterprise on the microeconomic level are described. Possible practical methods of risk management for the implementation of adopted decisions are proposed. The paper proves the fact that the complex nature of the management of the economic safety of the tourism enterprise and securing the sufficiently efficient management system of detecting and eliminating the threats are provided by the establishment of the management of the economic safety system of the tourism enterprise and its functional components. Research of the methodical approaches to the management of the tourism enterprises’ economic safety allows building and describing the functional structure of the mechanism of management of the tourist enterprise’s economic safety (it is formalized and described by 5 functions: determination of aims; planning; organization and adjusting; motivation and stimulation; control and monitoring).

Determination of Selected Phthalates in Some Commercial Cosmetic Products by HPLC-UV

2020 ◽  
Vol 23 (10) ◽  
pp. 1010-1022
Author(s):  
Emrah Dural
Keyword(s):  
High Performance ◽  
Phthalate Esters ◽  
High Sensitivity ◽  
Hplc Method ◽  
Cosmetic Products ◽  
Limit Of Quantification ◽  
Nail Polish ◽  
Accuracy And Precision ◽  
Butyl Phthalate

Aim and scope: Due to the serious toxicological risks and their widespread use, quantitative determination of phthalates in cosmetic products have importance for public health. The aim of this study was to develop a validated simple, rapid and reliable high-performance liquid chromatography (HPLC) method for the determination of phthalates which are; dimethyl phthalate (DMP), diethyl phthalate (DEP), benzyl butyl phthalate (BBP), di-n-butyl phthalate (DBP), di(2- ethylhexyl) phthalate (DEHP), in cosmetic products and to investigate these phthalate (PHT) levels in 48 cosmetic products marketing in Sivas, Turkey. Materials and Methods: Separation was achieved by a reverse-phase ACE-5 C18 column (4.6 x 250 mm, 5.0 μm). As the mobile phase, 5 mM KH2PO4 and acetonitrile were used gradiently at 1.5 ml min-1. All PHT esters were detected at 230 nm and the run time was taking 21 minutes. Results: This method showed the high sensitivity value the limit of quantification (LOQ) values for which are below 0.64 μg mL-1 of all phthalates. Method linearity was ≥0.999 (r2). Accuracy and precision values of all phthalates were calculated between (-6.5) and 6.6 (RE%) and ≤6.2 (RSD%), respectively. Average recovery was between 94.8% and 99.6%. Forty-eight samples used for both babies and adults were successfully analyzed by the developed method. Results have shown that, DMP (340.7 μg mL-1 ±323.7), DEP (1852.1 μg mL-1 ± 2192.0), and DBP (691.3 μg mL-1 ± 1378.5) were used highly in nail polish, fragrance and cream products, respectively. Conclusion: Phthalate esters, which are mostly detected in the content of fragrance, cream and nail polish products and our research in general, are DEP (1852.1 μg mL-1 ± 2192.0), DBP (691.3 μg mL-1 ± 1378.5) and DMP (340.7 μg mL-1 ±323.7), respectively. Phthalates were found in the content of all 48 cosmetic products examined, and the most detected phthalates in general average were DEP (581.7 μg mL-1 + 1405.2) with a rate of 79.2%. The unexpectedly high phthalate content in the examined cosmetic products revealed a great risk of these products on human health. The developed method is a simple, sensitive, reliable and economical alternative for the determination of phthalates in the content of cosmetic products, it can be used to identify phthalate esters in different products after some modifications.

Recent Applications of High Performance Thin Layer Chromatography and Derivative Spectrophotometry in Pharmaceutical Analysis

2020 ◽  
Vol 16 (6) ◽  
pp. 671-689
Author(s):  
Marcin Gackowski ◽  
Marcin Koba ◽  
Katarzyna Mądra-Gackowska ◽  
Piotr Kośliński ◽  
Stefan Kruszewski
Keyword(s):  
Thin Layer ◽  
Thin Layer Chromatography ◽  
Pharmaceutical Analysis ◽  
High Performance ◽  
Degradation Products ◽  
Derivative Spectrophotometry ◽  
Accuracy And Precision ◽  
Post Marketing ◽  
Layer Chromatography

At present, no one can imagine drug development, marketing and post-marketing without rigorous quality control at each stage. Only modern, selective, accurate and precise analytical methods for determination of active compounds, their degradation products and stability studies are able to assure the appropriate amount and purity of drugs administered every day to millions of patients all over the world. For routine control of drugs simple, economic, rapid and reliable methods are desirable. The major focus of current scrutiny is placed on high-performance thin layer chromatography and derivative spectrophotometry methods, which fulfill routine drug estimation’s expectations [1-4]. The present paper reveals state-of-the-art and possible applications of those methods in pharmaceutical analysis between 2010 and 2018. The review shows advantages of high-performance thin layer chromatography and derivative spectrophotometry, including accuracy and precision comparable to more expensive and time-consuming methods as well as additional fields of possible applications, which contribute to resolving many analytical problems in everyday laboratory practice.

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