scholarly journals The correlates and intensity of COVID-19 vaccine brand preferences in Canada

2021 ◽  
Author(s):  
Eric Merkley ◽  
Peter John Loewen
Keyword(s):  
Vaccine Hesitancy ◽  
Efficacy And Safety ◽  
Cross Sectional Survey ◽  
Cross Sectional ◽  
Perceived Efficacy ◽  
Perceived Safety ◽  
Demographic Correlates ◽  
Important People ◽  
Brand Effects ◽  
Brand Preferences

Most work on COVID-19 vaccine hesitancy has focused on its attitudinal and demographic correlates of individuals, but the characteristics of vaccines themselves also appear to be important. People are more willing to take vaccines with higher reported levels of efficacy and safety. Has this dynamic sparked hesitancy towards specific vaccines? We conduct a series of cross-sectional survey experiments to test for brand-based differences in vaccination intention, perceived efficacy, and perceived safety. Examining more than 6,500 individuals in a series of cross-sectional surveys, we find that respondents report less willingness to take AstraZeneca and Johnson & Johnson vaccines compared to those from Pfizer and Moderna, despite all vaccines being approved as safe by a federal regulator. Further, these brand preferences are meaningful: respondents report willingness to wait months for their preferred vaccine over AstraZeneca. We show that these brand effects are strongest among people who are usually most open to mass vaccination efforts. Our findings call for additional research on the determinants and consequences of COVID-19 vaccine-specific hesitancy and communication strategies to minimize this challenge.

scholarly journals What is associated with increased side effects and lower perceived efficacy following switching to a generic medicine? A New Zealand cross-sectional patient survey

BMJ Open ◽  
2018 ◽  
Vol 8 (10) ◽  
pp. e023667 ◽  
Author(s):  
Kate MacKrill ◽  
Keith J Petrie
Keyword(s):  
New Zealand ◽  
Side Effects ◽  
Generic Version ◽  
Drug Efficacy ◽  
Patient Survey ◽  
Generic Medicine ◽  
Cross Sectional Survey ◽  
Online Questionnaire ◽  
Cross Sectional ◽  
Perceived Efficacy

ObjectiveFollowing a switch from either a generic or branded antidepressant (venlafaxine) to a new generic, we investigated the factors associated with a preference for branded medicines, side effects reported following switching and efficacy ratings of the new generic drug.DesignA cross-sectional survey of patients switched to a new generic.SettingPatients accessing venlafaxine information online from the New Zealand government pharmaceuticals funding website.Participants310 patients, comprising 205 originally on branded venlafaxine and 105 previously taking a generic version.Main outcome measuresAn online questionnaire assessing demographic factors, perceived sensitivity to medicines, trust in pharmaceutical agencies, sources of switch information, preference for branded medicine, new medicine perceptions, side effects and efficacy ratings.ResultsPreference for branded medicine was significantly stronger in older patients (OR=1.04, 95% CI 1.01 to 1.05), those taking branded venlafaxine (OR=2.02, 95% CI 1.13 to 3.64) and patients with a higher perceived sensitivity to medicine (OR=1.23, 95% CI 1.06 to 1.19). Different factors predicted side effects in those switching from the branded and those switching from the generic venlafaxine. Trust in pharmaceutical agencies and the number of side effects were significant predictors of efficacy ratings of the new generic in both patients switching from a branded and those switching from a generic version of venlafaxine.ConclusionsIn patients switching from a branded medicine and those already taking a generic, different demographic and psychological factors are associated with preference for branded medicine, side effect reporting and perceived efficacy of the new drug. When switching to new generic, there appears to be a close bidirectional relationship between the experience of side effects and perceived drug efficacy. Trust in pharmaceutical agencies impacts directly on perceived efficacy and increasing such trust could reduce the nocebo response following a generic switch.

Patterns and perceived efficacy of herbal medicine for weight loss and maintenance: A cross-sectional survey from Jordan

2020 ◽  
Vol 35 ◽  
pp. 101086
Author(s):  
Amal Akour ◽  
Violet Kasabri ◽  
Nailya Bulatova ◽  
Suha Al Muhaissen ◽  
Ruba Al Tarawneh ◽  
...  
Keyword(s):  
Weight Loss ◽  
Herbal Medicine ◽  
Cross Sectional Survey ◽  
Cross Sectional ◽  
Perceived Efficacy

scholarly journals Acceptance Rates and Beliefs toward COVID-19 Vaccination among the General Population of Pakistan: A Cross-Sectional Survey

2021 ◽  
Author(s):  
Farah Yasmin ◽  
Waleed Asghar ◽  
Maryam Salma Babar ◽  
Hiba Khan ◽  
Shoaib Ahmad ◽  
...  
Keyword(s):  
General Population ◽  
Cross Sectional Study ◽  
Vaccine Hesitancy ◽  
Cross Sectional Survey ◽  
Cross Sectional ◽  
The Public ◽  
Polio Vaccination ◽  
Acceptance Rates ◽  
To Receive ◽  
Do So

Developing countries like Pakistan have previously suffered from barriers to acceptance of vaccination by the public because of financial and belief barriers. This study aims to explore these beliefs and highlight concerns regarding vaccine hesitancy in the general population of Pakistan since they are a hindrance to an effective coronavirus disease-19 (COVID-19) immunization in the country. A cross-sectional study was performed involving 1,778 participants from all four provinces of Pakistan. Results from the study showed more than half of the participants to be unsure of the safety (50%) and efficacy (51%) of the vaccine, whereas 42% were concerned about the side effects of the vaccine. About 72% of the respondents planned to get vaccinated, whereas 28% refused to do so. Internationally made imported vaccines were more trusted by the participants. Forty-four percent of the participants agreed to receive the vaccine upon recommendation from a physician. Lastly, participants who believed in the efficacy of the polio vaccination also considered the COVID-19 vaccine to be safe and effective.

scholarly journals Public awareness and acceptance of COVID-19 vaccine: An online cross-sectional survey, conducted in the first phase of vaccination drive in India

2021 ◽  
Author(s):  
Arumuganainar Suresh ◽  
Rocktotpal Konwarh ◽  
Anand Pratap Singh ◽  
Anand Krishna Tiwari
Keyword(s):  
Public Awareness ◽  
Clinical Trial Data ◽  
Knowledge Score ◽  
Vaccine Hesitancy ◽  
Cross Sectional Survey ◽  
Online Questionnaire ◽  
Cross Sectional ◽  
Specific Complex ◽  
Context Specific ◽  
Knowledge And Acceptance

Abstract The context-specific, complex issue of ‘vaccine hesitancy’ is explicated in terms of delay or refusal of vaccination despite the availability of vaccine services. Although eleven million beneficiaries were administered the COVID-19 vaccine in India from 16th January 2021 till 20th February 2021, however, proportionately a low turnout has been registered in various parts of the country, possibly attributable to hesitance/apprehension towards the current vaccination. In this backdrop, we report the response (collected between Feb 1, 2021 and Feb 15, 2021) of 358 voluntary respondents who participated in an online questionnaire-based pan-India survey, executed to assess their knowledge and acceptance towards the current COVID-19 vaccination program in its first phase. The survey questionnaire consisted of demographic characteristics of the respondents and queries pertaining to knowledge (7 items) and acceptance (3 items). The overall correct rate and the average knowledge score of the participants were 78 % and 5.46 ± 1.4/7 respectively. The acceptance score was 3.50 ± 1.6/5 while 70 % of participants agreed against the 20 % of respondents who neither agreed nor disagreed to take the vaccine. Around 66 % believed that the vaccines, currently being administered in India are safe. Fear about possible side effects (44 %) and inadequacy of comprehensive clinical trial data (29 %), seemed to be the major players in fortifying the vaccine hesitancy among the respondents, exhibiting negative acceptance. Although maximum respondents demonstrated a good level of knowledge (82%) and acceptance (88%), significant differences were observed among some demographic variables. In general, a positive correlation was observed between knowledge and acceptance against a negative correlation, observed in specific provinces. Despite the good acceptance and knowledge, a considerable fraction of the participants (30%) expressed hesitancy. Counselling, mobilization, and feedback from vaccinated individuals about safety should be encouraged. However, due to the limited sample size, we must be cautious when generalizing these findings. Nevertheless, the major elucidations of this study may be utilized in planning vaccination campaigns in further phases.

scholarly journals COVID-19 vaccine hesitancy in underserved communities of North Carolina

PLoS ONE ◽  
2021 ◽  
Vol 16 (11) ◽  
pp. e0248542
Author(s):  
Irene A. Doherty ◽  
William Pilkington ◽  
Laurin Brown ◽  
Victoria Billings ◽  
Undi Hoffler ◽  
...  
Keyword(s):  
North Carolina ◽  
Health Care Providers ◽  
Vaccine Safety ◽  
The United States ◽  
Vaccine Hesitancy ◽  
Care Providers ◽  
Cross Sectional Survey ◽  
Cross Sectional ◽  
Underserved Communities ◽  
Safety Concerns

Background In the United States, underserved communities including Blacks and Latinx are disproportionately affected by COVID-19. This study sought to estimate the prevalence of COVID-19 vaccine hesitancy, describe attitudes related to vaccination, and identify correlates among historically marginalized populations across 9 counties in North Carolina. Methods We conducted a cross-sectional survey distributed at free COVID-19 testing events in underserved rural and urban communities from August 27 –December 15, 2020. Vaccine hesitancy was defined as the response of “no” or “don’t know/not sure” to whether the participant would get the COVID-19 vaccine as soon as it became available. Results The sample comprised 948 participants including 27.7% Whites, 59.6% Blacks, 12.7% Latinx, and 63% female. 32% earned <$20K annually, 60% owned a computer and ~80% had internet access at home. The prevalence of vaccine hesitancy was 68.9% including 62.7%, 74%, and 59.5% among Whites, Blacks, and Latinx, respectively. Between September and December, the largest decline in vaccine hesitancy occurred among Whites (27.5 percentage points), followed by Latinx (17.6) and only 12.0 points among Blacks. 51.2% of respondents reported vaccine safety concerns, 23.7% wanted others to get vaccinated first, and 63.1% would trust health care providers about the COVID-19 vaccine. Factors associated with hesitancy in multivariable logistic regression included being female (OR = 1.90 95%CI [1.36, 2.64]), being Black (OR = 1.68 1.16, 2.45]), calendar month (OR = 0.76 [0.63, 0.92]), safety concerns (OR = 4.28 [3.06, 5.97]), and government distrust (OR = 3.57 [2.26, 5.63]). Conclusions This study engaged the community to directly reach underserved minority populations at highest risk of COVID-19 that permitted assessment of vaccine hesitancy (which was much higher than national estimates), driven in part by distrust, and safety concerns.

scholarly journals 1172. SARS-CoV-2 Vaccine Hesitancy in Caregivers of Hospitalized Children

2021 ◽  
Vol 8 (Supplement_1) ◽  
pp. S677-S677
Author(s):  
Marisa Orbea ◽  
Rachel Cunningham ◽  
C Mary Healy ◽  
Julie A Boom ◽  
Claire Bocchini
Keyword(s):  
Vaccine Uptake ◽  
Vaccine Hesitancy ◽  
Hospitalized Children ◽  
Parent Attitudes ◽  
Cross Sectional Survey ◽  
Cross Sectional ◽  
Vaccine Acceptance ◽  
And Behaviors ◽  
Childhood Vaccines ◽  
To Receive

Abstract Background SARS-CoV-2 vaccine hesitancy (VH) is hindering nationwide vaccination efforts; little is known about caregiver SARS-CoV-2 vaccine acceptance for children. We aimed to identify associations with SARS-CoV-2 VH in caregivers of hospitalized children. Methods We conducted a prospective cross-sectional survey in English and Spanish of caregiver COVID-19 knowledge, attitudes, behaviors, and associated VH among hospitalized children 6 months - 18 years at a large pediatric medical institution. Parents were approached daily, averaging 4-5 days/week, from 12/8/2020--4/5/2021. VH was assessed using the Parent Attitudes about Childhood Vaccines (PACV) survey; PACV score ≥50 denoted VH. Descriptive statistics and multivariable logistic regression were used. Responses were categorized. Results 295/307 (96%) of approached caregivers enrolled; 79% were ≥ 30 years, 68% were married/ living with a partner, and 57% had at least some college. 36% identified as white, 19% Black, and 46% Hispanic/ Latino. 53% of caregiver children had public insurance. 91% of caregivers self-reported their children were up to date with routine vaccines. 17% of caregivers were vaccine-hesitant overall. 50% of caregivers were willing to receive COVID-19 vaccine themselves. Figure 1 shows intention to vaccinate their child by PACV score. 65% knew someone who was hospitalized for COVID-19. 67% were scared of their child getting COVID-19. However, 49% were scared of their child getting the vaccine, 28% did not want to vaccinate their child and 27% were neutral in the intention to vaccinate their child. Caregivers who did not intend to vaccinate their child were more likely to be Black (27% vs. 16%, p=0.04) and less likely to be Hispanic/ Latino (33% vs. 49%, p=0.02). Table 1 shows attitudes, beliefs, and behaviors surrounding the COVID-19 pandemic and vaccine in caregivers who did or did not intend to vaccinate their child. Figure 1 COVID-19 vaccine uptake by PACV score Table 1 Caregiver attitudes, beliefs, and behaviors surrounding the COVID-19 pandemic and the COVID-19 vaccine Conclusion The majority of caregivers believe that SARS-CoV-2 vaccine will help control the pandemic, but less than half plan to vaccinate their children. A quarter of caregivers expressed uncertainty regarding the vaccine and therefore may be amenable to education and discussion. COVID-19 VH is different from VH towards routine vaccinations. More research is needed to address COVID-19 specific VH. Disclosures C. Mary Healy, MD, Dexcom (Shareholder)Intuitive (Shareholder)Quidel Corporation (Shareholder)Up to Date (Other Financial or Material Support, Honorarium)Vapotherm (Shareholder)

scholarly journals Acceptability of the Coronavirus Disease-2019 Vaccine Among Medical Students in Uganda: a Cross Sectional Study.

2021 ◽  
Author(s):  
Andrew Marvin Kanyike ◽  
Ronald Olum ◽  
Jonathan Kajjimu ◽  
Daniel Ojilong ◽  
Grabriel Madut Akech ◽  
...  
Keyword(s):  
Medical Students ◽  
Perceived Risk ◽  
Cross Sectional Study ◽  
Vaccine Hesitancy ◽  
Cross Sectional Survey ◽  
Future Health ◽  
Vaccine Acceptability ◽  
Cross Sectional ◽  
The Future ◽  
Global Threat

Abstract Background COVID-19 is still a major global threat and vaccination remains the long-lasting solution. Unanimous uptake of the COVID-19 vaccine is required to subsequently avert its spread. We therefore, assessed COVID-19 vaccine acceptability, hesitancy, and associated factors among medical students in Uganda. Methods This study employed an online descriptive cross-sectional survey among medical students across 10 medical schools in Uganda. A structured questionnaire as a Google form was sent to participants via WhatsApp. Data was extracted and analyzed using Microsoft Excel 2016 and STATA 16. Descriptive statistics, bivariate and multivariable analyses were performed. Results We surveyed 600 medical students, 377 (62.8%) were male. COVID-19 vaccine hesitancy and acceptability were 30.7% and 37.3%, respectively. Factors associated with vaccine acceptability were being female (aOR = 1.9, 95% CI: 1.3–2.9, p = 0.001), being single (aOR = 2.1, 95% CI 1.1–3.9, p = 0.022). Very high (aOR = 3.5, 95% CI 1.7–6.9, p < 0.001) or moderate (aOR = 2.2, 95% CI 1.2–4.1, p = 0.008) perceived risk of getting COVID-19 in the future, receiving any vaccine in the past 5 years (aOR = 1.6, 95% CI 1.1–2.5, p = 0.017), and COVID-19 vaccine hesitancy (aOR 0.6, 95% CI 0.4–0.9, p = 0.036). Conclusions This study revealed low levels of acceptance towards the COVID-19 vaccine among medical students, low self-perceived risks of COVID-19, and many had relied on social media that provided them with negative information. This poses an evident risk on the battle towards COVID-19 in the future especially when these future health professions are expected to be influencing decisions of the general public towards the same.

Sign in / Sign up

Export Citation Format

Share Document