scholarly journals A study on the demographic, clinical, and radiological profile of lineage B.1.1.7 (United Kingdom) strain Covid-19 patients at Telangana institute of medical sciences and research, Hyderabad

2022 ◽  
Vol 13 (1) ◽  
pp. 13-18
Author(s):  
Jayasri Helen Gali ◽  
Manasa Musku ◽  
Devireddy Pallavi Reddy ◽  
Vimala Thomas ◽  
Ehsan Ahmed Khan

Background: Emergence of variants with specific mutations in key epitopes in the spike protein of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) raises concerns pertinent to its severity. Aims and Objectives: To assess the demographics, clinico-radiological pattern, and outcome of reverse transcription-polymerase chain reaction (RT-PCR) positive isolated coronavirus disease 2019 (COVID-19) patients arrived from the United Kingdom (UK). Materials and Methods: A cross-sectional, observational study was conducted in RT-PCR positive COVID-19 patients arrived from the UK, from December 2020 to February 2021. Nasopharyngeal samples of all patients were sent for whole-genome sequencing of SARS-CoV-2. The aimed parameters were compared between the B.1.17 positive and non-B.1.1.7 groups, among the people, arrived from the UK. All statistical tests with P<0.05 were considered significant. Results: A total of 59 SARS-CoV2 infected patients, who arrived from the UK, were isolated from December 2020 to February 2021 at Telangana Institute of Medical Sciences hospital, Hyderabad, were enrolled in the study. Of these, 27 patients (mean age-31.81±11.28 years) were infected with the B.1.1.7, diagnosed by whole genomic sequencing. Males were predominant in our study. Personal habits such as smoking, alcohol intake were higher among the sequenced group with a significant P<0.05. The most common symptoms observed in the sequenced group were cough (22.22%), sore throat (22.22%), cold (11.11%), fever (11.11%), and in the unsequenced group were cough (22.22%), cold (6.25%), fever (6.25%). In the sequenced group, chest X-ray posteroanterior view was normal in 74%, patchy ground-glass opacities was observed in 25.92% patients, whereas in the unsequenced group it was 84.37% and 15.62%, respectively. Asymptomatic patients, observed in the sequenced and unsequenced group were 48.18% and 78.12%, respectively, and symptomatic patients were 51.85% and 21.87%, respectively. We found a statistically significant difference between sequenced and unsequenced patients in the asymptomatic group with a significant P<0.05. In the sequenced and unsequenced group, mild cases were 48.18% and 18.75%, moderate cases were 3.7% and 3.12%, respectively. We found no evidence of an association between disease severity and lineage B.1.17. Conclusion: Our data, within the context and limitations of a real-world study, provide initial reassurance that severity in hospitalized patients with B.1.1.7 is not markedly different from severity in those without B.1.1.7.

2018 ◽  
Vol 7 (2.13) ◽  
pp. 309 ◽  
Author(s):  
Reza Pourmirza Kalhori ◽  
Frank Mousavi ◽  
Soosan Laei ◽  
Soodeh Shahsavari

Successful succession management is one of the necessities in any organization, especially universities. In the management of higher education, succession planning deployment requires proprietary methods. Therefore, the present study aimed to investigate the status quo and favorable status of succession management deployment from the viewpoint of faculty members at Kermanshah University of Medical Sciences in 2017. In this descriptive-analytic and cross-sectional study, 95 faculty members were selected from the Departments of Basic Sciences and Clinical Sciences using nonrandom quota sampling. As for data collection, the Kim's succession planning questionnaire was employed. To analyze data, the SPSS Statistical Software Version 23.0 and the statistical tests of paired t-test, Chi-square and ANOVA were used to compare the status quo of succession management deployment with its favorable status and to study its decisive factors. The results of the present study revealed that there was a significant difference between the status quo and favorable status of t succession management deployment (P<0.0001). The results also demonstrated that there was a significant difference between the status quo of succession management deployment and its favorable status in terms of policy setting, evaluation of candidates, development of candidates, and system evaluation (P<0.001). Moreover, the results indicated that the greatest deployment in the status quo was related to the evaluation of candidates whereas the greatest deployment in the favorable status belonged to policy setting. The findings of the present study demonstrated that there was a clear gap between the status quo and favorable status of succession management deployment from the perspective of faculty members. Hence, it is recommended that qualifications-based selection be employed as the basis on which succession management and talent management can be deployed successfully and effectively at medical universities.  


2017 ◽  
Vol 10 (4) ◽  
pp. 248-255 ◽  
Author(s):  
Sedigheh Salavati ◽  
Mohammad Amerzadeh ◽  
Amjad Mohammadi Bolbanabad ◽  
Bakhtiar Piroozi ◽  
Shilan Amirihoseini

Purpose Prediction of future changes and making appropriate strategic decisions require strategic thinking in any organization. It helps managers to create new opportunities. The purpose of this paper is to measure strategic thinking and its affecting factors at Kurdistan University of Medical Sciences. Design/methodology/approach This is a descriptive-analytic as well as a cross-sectional study which was conducted in 2016. Its statistical community included 300 managers and personnel of Kurdistan University of Medical Sciences. The sample size was equal to statistical community. Data were collected using a standard questionnaire. Data were then entered into SPSS20 and were analyzed using statistical tests such as Freedman, Whitney and Kruskal-Wallis. Findings Overall, strategic thinking was evaluated “good” and “somewhat good” among managers (5.0±72.28) and personnel (6.0±25.48), respectively. Moreover, among the elements of strategic thinking, conceptual thinking obtained the highest score among both managers (6.0±06.32) and personnel (5.0±53.52), which was evaluated in a “good” level. There was a significant difference between managers’ and personnel’s strategic thinking score (p=0.001). Different education groups of managers and personnel were different in terms of strategic thinking (p<0.05), but strategic thinking score of managers and personnel were not significant based on the work experience and type of employment. Originality/value Although both managers and personnel received a good score in terms of strategic thinking, improving the level of strategic thinking especially for future trends and opportunities can lead to enhanced strategic thinking among managers and personnel of Kurdistan University of Medical Sciences.


Author(s):  
Curtis R Budden ◽  
Francesca Rannard ◽  
Joanna Mennie ◽  
Neil Bulstrode

Abstract Background Surgical trainees worldwide have been thrust into a period of uncertainty, with respect to the implications COVID-19 pandemic will have on their roles, training, and future career prospects. It is currently unclear how plastic surgery trainees are being affected by COVID-19. This study examined the experience of plastic surgery trainees in Canada, the UK, and Australia to determine trainee roles during the early COVID-19 emergency response and how training changed during this time. Methods A cross-sectional survey-based study was designed for plastic surgery trainees in the UK, Canada and Australia. In total, 110 trainees responded to the survey. Statistical tests were conducted to determine differences in responses, based on year of training and country of residence. Results In total, 9.7% (10/103) of respondents reported being deployed to cover another service. There was a significant difference between redeployment based on country (p = 0.001). Within the UK group, 28.9% of respondents were redeployed. For trainees not deployed, 95.5% (85/89) reported that there has been a reduction in operative volume. Ninety-seven (94.1%) respondents reported that there were ongoing teaching activities offered by their program. The majority of trainees (66.4%) were concerned about their training. There was a significant difference between overall concern and country (p < 0.05). Conclusion In these unprecedented times, training programs in plastic surgery should be aware of the major impact that COVID-19 has had on trainees and will have on their training. The majority of plastic surgery trainees have experienced a reduction in surgical exposure but have maintained some form of regular teaching.


2021 ◽  
pp. bjophthalmol-2020-318236
Author(s):  
Ralene Sim ◽  
Gemmy Cheung ◽  
Daniel Ting ◽  
Edmund Wong ◽  
Tien Yin Wong ◽  
...  

Background/aimsTo explore if retinal findings are associated with COVID-19 infection.MethodsIn this prospective cross-sectional study, we recruited participants positive for COVID-19 by nasopharyngeal swab, with no medical history. Subjects underwent retinal imaging with an automated imaging device (3D OCT-1 Maestro, Topcon, Tokyo, Japan) to obtain colour fundus photographs (CFP) and optical coherence tomographic (OCT) scans of the macula. Data on personal biodata, medical history and vital signs were collected from electronic medical records.Results108 patients were recruited. Mean age was 36.0±5.4 years. 41 (38.0%) had symptoms of acute respiratory infection (ARI) at presentation. Of 216 eyes, 25 (11.6%) had retinal signs—eight (3.7%) with microhaemorrhages, six (2.8%) with retinal vascular tortuosity and two (0.93%) with cotton wool spots (CWS). 11 eyes (5.1%) had hyper-reflective plaques in the ganglion cell-inner plexiform layer layer on OCT, of which two also had retinal signs visible on CFP (CWS and microhaemorrhage, respectively). There was no significant difference in the prevalence of retinal signs in symptomatic versus asymptomatic patients (12 (15.0%) vs 13 (9.6%), p=0.227). Patients with retinal signs were significantly more likely to have transiently elevated blood pressure than those without (p=0.03).ConclusionOne in nine had retinal microvascular signs on ocular imaging. These signs were observed even in asymptomatic patients with normal vital signs. These retinal microvascular signs may be related to underlying cardiovascular and thrombotic alternations associated with COVID-19 infection.


2020 ◽  
Vol In Press (In Press) ◽  
Author(s):  
Mahnaz Zarshenas ◽  
Mozhgan Sorkhenezhad ◽  
Marzieh Akbarzadeh

Background: Uterine leiomyomas are considered as a major source of complications and the most common cause of hysterectomy. Objectives: The aim of this study was to compare the quality of life in women with and without uterine leiomyoma referred to gynecology clinics of Shiraz University of Medical Sciences in 2018. Methods: In this cross-sectional study, a total of 126 patients who referred to the clinics of Shiraz University of Medical Sciences were selected and divided into equal groups according to uterine leiomyoma, 1 - 7 cm uterine leiomyoma group and non-uterine leiomyoma group by convenience sampling. The World Health Organization Quality of Life and Healthy Lifestyle questionnaires were used for data collection. Independent t-test was used to analyze the data. Results: The mean quality of life of women with uterine leiomyoma was 47.20 ± 12.41 and women without uterine leiomyoma had a significant difference (51.11 ± 11.23, t = 3.93, P = 0.041). The mean lifestyle of women with uterine leiomyoma was 114.18 ± 25.48 and women without uterine leiomyoma had 149.11 ± 23.81 (t = 4.01, P = 0.029). Conclusions: The mean score of quality of life and lifestyle were significantly different in women with and without uterine leiomyoma. Therefore, it is necessary to improve the quality of life of women by improving their lifestyle and providing psychological counseling.


2021 ◽  
Vol 15 (6) ◽  
pp. 1847-1853
Author(s):  
Sahar Attar ◽  
Nour Mohammad Bakhshani ◽  
Qasem Miri Aliabad

Background and Aim: Thalassemia major is one of the most common chronic genetic diseases in the world and in Iran that can impose many adverse effects on the self and society. Psychologically, patients with thalassemia are under stress. According to the World Health Organization (WHO), suicide is one of the leading causes of death worldwide. It is important to identify the people who have the highest risk factors for suicide. The present research investigates the frequency of thoughts, readiness and suicide attempts in people with thalassemia. Methods: This was a cross-sectional study. Its sample was 150 patients with thalassemia in the age range of 10 to 46 years whom we selected through census by sampling at convenience. We gave to patients a standardized Beck Suicide Thought Assessment Questionnaire. We analyzed the research data using descriptive and inferential statistical tests. Results: From among 150 patients with thalassemia in this study, 57.3% of the respondents were male and 42.7% were female. The results showed that there was a negative and significant relationship between suicide thoughts and attempts and age (-0.234) (P <0.05). The mean prevalence of suicide in men (1.89) was significantly higher compared to women (0.79) (P <0.05). We did not observe significant difference in prevalence of suicide thoughts and attempts between married and single groups with a mean difference (0.69) (P <0.05) and, in different educational groups, no significant difference was reported (P> 0.05). Conclusion: The findings of this research showed that among patients with thalassemia, the prevalence of suicidal ideation has a significant percentage. Since suicidal ideation provides a platform for preparation and attempt to commit suicide, so by providing mental health services and regular screening, we can take an effective step to prevent this problem among patients with thalassemia. Keywords: Thalassemia, Suicidal ideation, Suicide.


2021 ◽  
Author(s):  
Hiva Bozorgpanah ◽  
Ghobad Moradi ◽  
Pourya Bahrami ◽  
Elham Noori ◽  
Mohammad Pourya Ezati ◽  
...  

Abstract Background and Aim: the present study was conducted to investigate social media statistics of usage and its determinant factors in students of Kurdistan University of Medical Sciences in 2018.Materials and Methods: This study is a cross-sectional-analytical study. The total of 380 students of Kurdistan University of Medical Sciences were randomly selected by Probability Proportional to Size Sampling method, from the lists of the students in each faculty. The data collection tool was a researcher-made questionnaire, organized in four sections. Data analysis was done using descriptive and inferential statistics by SPSS software version 21.Results: Based on the results of this study 373 (98.2%) of the sample students were on social media, which the most popular ones among them were Telegram (94.1%), Instagram (78.8%) and Whatsapp (61.9%), respectively. The average time spent on social media among students was reported to be 2.78 hours per day and is a significant difference between age groups in terms of attitudes toward using social media (P = 0.031).Conclusion: the results of this study suggested that the majority of students use social media. Since improper use of social media can exert unfortunate effects on different aspects of life of students, and negatively influence their education.


2019 ◽  
Vol 5 (4) ◽  
pp. 185-189
Author(s):  
Mohammadreza Emamhadi ◽  
◽  
Hamid Behzadnia ◽  
Seifollah Jafari ◽  
Mohammadreza Zamanidoust ◽  
...  

Background: Postoperative pain is a common phenomenon, and its management affects considerably on the recovery process, and patients’ satisfaction. Apotel and pethidine are two conventional medicines used to relieve pain after operation. Objectives: The present study aimed to compare the effect of intravenous injection of Apotel and intramuscular injection of pethidine in relieving pain after hemilaminectomy. Materials & Methods: In the present cross-sectional study, 150 patients who underwent hemilaminectomy were recruited between May 2015 and November 2015. They were taking either Apotel (n=75) or pethidine (n=75) after the operation, which was done at Poursina Hospital affiliated to Guilan University of Medical Sciences, Rasht City, Iran. The patients’ pain levels were measured using visual analog scale (VAS), and the results were compared between the 2 groups. Results: There was no significant difference in the total VAS score between the Apotel and pethidine groups (P=0.189). However, there was a significant reduction in VAS score hours 2 (P=0.03) and 4 (P=0.004) hours after the injection of Apotel in this group, compared with those scores in the pethidine group. Also, VAS scores at other times (8, 12, 20, 28 hours after the injection) were lower than those in the pethidine group, but the difference was not significant. Conclusion: Apotel was better pain-killer in the early hours after the first injection compared to pethidine. But its effect was similar to pethidine at the late hours after the first injection. Therefore it seems that Apotel is better painkiller after laminectomy, especially in the early hours after the operation.


Author(s):  
Lensi Natalia Tambunan ◽  
Lelly Oktarina ◽  
Nita Kusuma Lindarsih

Latar Belakang: Mobilisasi dini pada ibu nifas bertujuan untuk membantu menguatkan otot-otot perut, sehingga memperbaiki sirkulasi darah ke seluruh tubuh. Hal ini harus dipenuhi ibu selama masa nifas untuk mengembalikan organ-organ reproduksi, terutama untuk ibu yang post sectio caesaria. Mobilisasi pada ibu post sectio caesaria adalah suatu pergerakan, posisi atau adanya kegiatan yang dilakukan ibu setelah beberapa jam melahirkan dengan persalinan Caesar Namun, kenyataannya masih banyak ibu post sectio caesaria yang tidak mau melakukan mobilisasi dini karena merasa takut, malas untuk bergerak, merasa sakit dan lelah. Faktor fisiologis seperti kenaikan suhu tubuh (hipertermi), perdarahan yang berlebihan, nyeri, faktoe emosional seperti terjadinya kecemasan dan factor perkembangan seperti usia dan paritas.Tujuan: Penelitian untuk mengetahui hubungan paritas dengan pengetahuan ibu post Sectio caesaria tentang mobilisasi dini di RSUD Doris Sylvanus Palangka Raya Provinsi Kalimantan Tengah.Metode: Desain penelitian  ini  bersifat kuantitatif analitik observasional dengan menggunakan jenis desain cross sectional dengan tehnik pengambilan sampel yang digunakan adalah Accidental Sampling. Populasi pada penelitian ini adalah seluruh ibu post sectio caesaria  di RSUD dr. Doris Sylvanus Palangka Raya. Pengumpulan data dilakukan dengan menggunakan data primer.Data dianalisis secara chi square. Hasil: Hasil uji statistik diperoleh P value 0,964, berarti tidak ada perbedaan secara bermakna sehingga dapat disimpulkan tidak ada hubungan antara paritas dengan pengetahuan ibu post sectio caesaria tentang mobilisasi dini.Simpulan: Ibu post sectio caesaria dengan paritas 2 agar tetap diberikan informasi mengenai mobilisasi dini post sectio caesaria agar ibu memiliki pengetahuan yang baik, jika ibu memiliki pengetahuan yang baik mengenai mobilisasi maka ibu akan melaksanakan mobilisasi diniKata Kunci: Paritas, Ibu post sectio caesaria, Mobilisasi Dini. Background: Early mobilization of the postpartum mother aims to help strengthen the abdominal muscles, thereby improving blood circulation throughout. This must be fulfilled by the mother during puerperium to restore the reproductive organs, especially for mothers who are post sectional caesaria.  Mobilization of post sectio caesaria mothers is a movement, position or activity carried out by the mother after several hours of childbirth with caesarean delivery. However, in reality there are still many post sectio caesaria mothers who do not want to make early mobilization because they are afraid, lazy to move, feel sick and tiredPhysiological factors such as increased body temperature (hypertension), excessive bleeding, pain, emotional factors such as anxiety and developmental factors such as age and parity. Objective: The study was to find out the relationship between parity and post Sectio caesaria mother's knowledge about early mobilization in Doris Sylvanus Hospital in Palangka Raya, Central Kalimantan Province.Method: The design of this study was quantitative analytic observational using a cross sectional design with the sampling technique used was accidental sampling. The population in this study were all post sectio caesaria mothers in RSUD dr. Doris Sylvanus Palangka Raya.  Data collection was done using primary data. Data was analyzed by chi square.Result: The result of statistical tests obtained p value 0.964 means that there is no significant difference so that it can be concluded there is no relationship between parity and post-caesaria maternal knowledge about early mobilization.Conclusion: Post-caeserean mothers with parity 2 keep informed about early post-caesarean mobilization so that mothers have good knowledge about mobilization, mothers will carry out early mobilization.Keywords: Parity, Maternal Caesarean section, Early Mobilization. 


2017 ◽  
Vol 8 (2) ◽  
pp. 56-58
Author(s):  
Garima Biyani ◽  
Swapan Kumar Ray ◽  
Kripasindhu Chatterjee ◽  
Sukanta Sen ◽  
Pradyut Kumar Mandal ◽  
...  

Background: Febrile convulsion (FC) is the most common seizure disorder in childhood. White blood cell (WBC) and C reactive protein (CRP) are commonly measured in FC. Add a paragraph on Aims and Objectives of the study.Aims and Objectives: To compare WBC and CRP in febrile children, aged 6 months to five years, with and without FC, in order to determine whether leukocytosis and elevated CRP can be used as diagnostic tool for febrile seizure.Materials and Methods: In this cross sectional study 214 children (112 with FC), aged 6 months to 5 years, admitted to in the first 48 hours of their febrile disease, either with or without seizure, were evaluated over a 12 months period. Age, sex, temperature; WBC, CRP and hemoglobin were recorded in all children. There was a significant increase of WBC (P<0.001) in children with FC so we can deduct that leukocytosis encountered in children with FC can be due to convulsion in itself.Results: When comparing FC and non-FC children, we encountered a significant increase of WBC (P =0.0005) in children with FC, measured at the time of admission to pediatric medicine ward. There was no significant difference regarding CRP between the two groups. In fact, elevated CRP is a result of underlying pathology.Conclusion: In stable patients, if there’s no reason to suspect a bacterial infection or who don’t have any indication of lumbar puncture, there’s no need to assess WBC as an indicator of underlying infection. Any child with febrile seizure with a high CRP value should be evaluated for infection.Asian Journal of Medical Sciences Vol.8(2) 2017 56-58


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