scholarly journals An Assessment of Asymptomatic Bacteriuria among Women with Vesico-Vaginal Fistula in South-Eastern Nigeria

1970 ◽  
Vol 1 (2) ◽  
pp. 64-69 ◽  
Author(s):  
Ileogben Sunday Adeoye ◽  
Oladapo Oladeinde ◽  
Jesse Uneke ◽  
Julie Adeoye

Objective: Vesico-vaginal fistula (VVF) involves the pathological communication between the urinary bladder and vagina, possible complications arising from urinary tract infection merits consideration. This study seeks to evaluate significant bacteriuria among VVF clients. Setting: The setting was the South east Fistula Centre, Abakaliki, Ebonyi State, Nigeria. Population: This was a total population study of all consenting HIV negative VVF clients. Method: This cross-sectional study assessing asymptomatic bacteriuria was conducted among 109 HIV negative VVF clients using standard microbiological technique. Haematological and anthropometric parameters were also assessed. Results: The prevalence of asymptomatic bacteriuria was 76.1% and the highest prevalence was among clients aged 21-30years (90.3%), those who have had more than seven deliveries (85.0%) and those whose labour duration lasted above 48hours (76.7%). The prevalence of bacteriuria was least among women with VVF for less than a year. The prevalence was highest among patients with intra cervical fistula (83.3%). Bacteriuria prevalence was highest among women of blood group AB (100%). The rate was higher among women whose heights were > 1.53metres and whose weights were < 51kilogram. Six different bacterial species isolated  include E. coli (41.0%), Proteus species (21.7%), and Klebsiella species (18.1%). Though the bacterial isolates were resistance to many of the antibiotics assessed, the highest level of resistance was observed with perfloxacin, cotrimoxazole, while the highest level of susceptibility was with Ciprofloxacin. Conclusion: The prevalence of bacteriuria in this study is rather high and should not be neglected in the management of VVF clients.Key Words: Assessment; Asymptomatic Bacteriuria; VVF; Southeast Nigeria.DOI: http://dx.doi.org/10.3126/nje.v1i2.5141 Nepal Journal of Epidemiology 2011;1 (2):64-69

2019 ◽  
Vol 48 (1) ◽  
pp. 39-43
Author(s):  
Shamima Akhter ◽  
Mst Mahbuba ◽  
Nusrat Ara Yusuf ◽  
Munirunnessa ◽  
Nasrin Rosy

Vesico-vaginal fistula (VVF) is still a major global health problem.This study was performed to detect the surgical outcome of 100 VVF patients in National Fistula Centre. A descriptive cross sectional study was carried out among 100 VVF patients fulfilling the inclusion criteria admitted in the National Fistula Centre under the department of Obstetrics and Gynaecology during the study period of April, 2017 to September, 2017. During the period, 100 patients presented for surgical repair at a mean age of 28.7 years (SD7.1). Majority of them (49%) had a parity of one and 57% were less than 20 years old at the time of their first pregnancy. About 83% of women developed VVF following prolonged obstructed labour. Most of the fistula (95%) repaired through vaginal route by flap splitting technique and 73% repaired at 1st time. Recovery of most of the patient (75%) was uneventful. Inadequate post-operative care (26.9%) was the major causes of unsuccessful repair. Obstetric fistula is one of the tragedies of third world countries and it would be better solved by providing surgical procedure and easy access of all women to competent obstetrical care, irrespective of their social and economic  status during pregnancy and delivery. Bangladesh Med J. 2019 Jan; 48 (1): 39-43


Author(s):  
Priya Paari ◽  
Sindhuja T. P. ◽  
Shanthi Dhinakaran ◽  
Christina Mary P. Paul

Background: Asymptomatic bacteriuria (ASB) in pregnancy is a treatable risk factor for preterm delivery. India accounts for the highest preterm birth incidence in the world according to the WHO census released in November 2016. This study was aimed at finding the prevalence of asymptomatic bacteriuria, the spectrum of bacteria involved and the susceptibility pattern for the antimicrobials in the antenatal women attending a tertiary care hospital in urban Southern India.Methods: One hundred and eighty ante-natal patients without symptoms of ongoing urinary tract infection were enrolled to this study. Clean midstream urine sample was collected in a wide mouthed container and sample was analyzed by standardized microbiological testing techniques.Results: Out of the 180 ante-natal women included in the study, 11(6.1%) patients were found to have insignificant bacteriuria and 38(21.1%) had a significant bacteriuria. E. coli was the most frequently isolated organism and about 95% of the organisms were sensitive to Nitrofurantoin.Conclusions: More than a fifth of all pregnant women have ASB and E. coli is the most frequent pathogen encountered.


2015 ◽  
Vol 4 (4) ◽  
pp. 159-63
Author(s):  
Mina Etminan-Bakhsh ◽  
Roksana Darabi ◽  
Sima Tadi ◽  
Mitra Mohit

Background: During pregnancy, asymptomatic bacteriuria is associated with different complications such as pyelonephritis and preterm birth. Pregnancy changes pave the way for the growth and multiplication of pathogenic factors. This study was aimed at exploring the frequency of asymptomatic bacteriuria among pregnant women who attended Boo–Ali Hospital, a teaching center of Islamic Azad University in Tehran. Materials and Methods: This cross-sectional study was performed on 123 pregnant women without urinary symptoms who attended Boo–Ali Hospital from March 2013 to September 2014. Demographic information of the patients including age, gestational age at the time of experiment and parity were recorded. An amount of middle part of urine (20cc) was collected in an appropriate sterile container. Urine samples were examined for WBC, RBC and bacteria. Other parts of the samples were cultivated for urine culture (U/C). Results: Two (1.6%) women had significant bacteriuria (≥105/ml). Pyuria, bacteriuria and hematuria were seen in 49(39.8), 7 (5.6%) and 8 (6.5%) women, respectively. There was a significant association between positive U/C and pyuria (P=0.003). However, positive U/C showed no significance association between bacteriuria and hematuria (P>0.05). Conclusion: Regarding the low frequency of asymptomatic bacteriuria (less than 2%) in the investigated population, the administration of U/C does not seem logical for all pregnant women. Hence, U/C is recommended for those with significant pyuria in their urinalyses. [GMJ.2015;4(4):159-63]


2019 ◽  
Vol 5 (1) ◽  
pp. 29-32
Author(s):  
Shimul Akter ◽  
Fouzia Mujib ◽  
Mohammed Masudur Rahman ◽  
Dewan Shahida Banu ◽  
Taslima Begum ◽  
...  

Background: Surgical management of vesico-vaginal fistula is very crucial regarding the outcomes among the women. Objectives: The purpose of the present study was to see the surgical outcomes of vesico-vaginal fistula. Methodology: This cross-sectional study was carried out from July 2013 to December 2013 for a period of 6 months in the National Fistula Centre in the Department of Obstetrics & Gynaecology at Dhaka Medical College Hospital (DMCH), Dhaka, Bangladesh. All patients who underwent surgical repair for iatrogenic VVF in National Fistula Centre of the department of Obstetrics and Gynaecology of Dhaka Medical College Hospital were included in this study. Patients who got themselves admitted to Obstetrics & Gynaecology department of DMCH with the complaints of fistula. An interview usually lasted for an hour. The entire selected patients were interviewed for detailed history. Thorough physical examination was done. The surgical outcomes were recorded among the women. Result: A total number of 51 cases of VVF were recruited for this study. The mean age was 46.02 (±SD 6.104) years. Regarding the causes of iatrogenic vesico-vaginal fistula most of the cases (88.2%) were abdominal hysterectomy. In 4(7.8%) patients lower segment caesarean section caused the situation. Vaginal hysterectomy was responsible for 3.9% (2/51) cases of iatrogenic VVF. In more than 90% cases (46/51) the surgical outcome was successful; while in 5 patients’ fistula recurred 5 to 7 days following surgery. They were treated by re-operation later on. Conclusion: In conclusion abdominal hysterectomy is the most common cause of iatrogenic vesico-vaginal fistula with a very good surgical outcomes. Journal of National Institute of Neurosciences Bangladesh, 2019;5(1): 29-32


2021 ◽  
Vol 27 (1) ◽  
Author(s):  
Olatunji O. Lawal ◽  
Rukiyat Adeola Abdus-salam ◽  
Oluwasomidoyin O. Bello ◽  
Imran O. Morhason-Bello ◽  
Oladosu A. Ojengbede

Abstract Background Obstetric fistula (OF) complicated by urethral loss (UL) poses a challenge to both the fistula surgeon and obstetric fistula patient. The involvement of the urethra and urethral closure mechanism in OF is an important determinant of successful closure of fistula and restoration of urinary continence. OF with UL is often associated with unsuccessful repair outcome. We describe urethral reconstruction in genital tract fistula patients with UL and the outcomes of the repair. Methods Aim To review the clinical characteristics and outcome of vesico-vaginal fistula associated urethral loss following urethral reconstruction. This was a descriptive cross-sectional study conducted at the University College Hospital, Ibadan, Nigeria. A 5-year prospective data of all vesico-vaginal fistula patients with urethral loss (2011–2016) were reviewed and analysed. Data collected include socio-demographic and obstetric characteristics; cause of the fistula; and fistula characteristics—type of fistula, number of previous repairs, urethral loss, outcome of repair and follow-up. Data were entered and analysed using IBM SPSS version 20. Results Urethral loss occurred in 23 (15.3%) out of 150 women with OF; these women had urethral reconstruction surgery. The commonest type of urethral loss encountered in this cohort was proximal urethral loss which was seen in 12 (52.2%) patients. The most common types of fistula seen with urethral loss were large vesico-vaginal fistula (34.8%) and mid-vaginal fistula (26.1%). More than half of the women (56.6%) had previous unsuccessful repair at other facilities before presentation. The fistula closure rate was high (82.6%) regardless of type of urethral loss. Among the women with successful closure of OF with UL, about 36.8% had urinary stress incontinence post-fistula repair. Conclusion Urethral loss appears to be a rare complication of obstetric fistula. Successful closure with stress incontinence was seen in a sizeable number of women with OF with UL. Preoperative assessment for determinant of post-repair incontinence and surgical repair by experienced surgeons will improve successful outcome of repair in women with obstetric fistula with UL.


Nutrients ◽  
2021 ◽  
Vol 13 (6) ◽  
pp. 2032
Author(s):  
Judit Companys ◽  
Maria José Gosalbes ◽  
Laura Pla-Pagà ◽  
Lorena Calderón-Pérez ◽  
Elisabet Llauradó ◽  
...  

We aimed to differentiate gut microbiota composition of overweight/obese and lean subjects and to determine its association with clinical variables and dietary intake. A cross-sectional study was performed with 96 overweight/obese subjects and 32 lean subjects. Anthropometric parameters were positively associated with Collinsella aerofaciens, Dorea formicigenerans and Dorea longicatena, which had higher abundance the overweight/obese subjects. Moreover, different genera of Lachnospiraceae were negatively associated with body fat, LDL and total cholesterol. Saturated fatty acids (SFAs) were negatively associated with the genus Intestinimonas, a biomarker of the overweight/obese group, whereas SFAs were positively associated with Roseburia, a biomarker for the lean group. In conclusion, Dorea formicigenerans, Dorea longicatena and Collinsella aerofaciens could be considered obesity biomarkers, Lachnospiraceae is associated with lipid cardiovascular risk factors. SFAs exhibited opposite association profiles with butyrate-producing bacteria depending on the BMI. Thus, the relationship between diet and microbiota opens new tools for the management of obesity.


2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Jasmin Grischke ◽  
Szymon P. Szafrański ◽  
Uthayakumar Muthukumarasamy ◽  
Susanne Haeussler ◽  
Meike Stiesch

Abstract Background The prevalence of peri-implantitis ranges between 7 and 38.4% depending on risk indicators such as smoking, diabetes mellitus, lack of periodontal maintenance program, and history or presence of periodontitis. Currently, the possible effect of the type of superstructure on peri-implant health is unclear. This cross-sectional study aims to investigate the influence of the superstructure on the prevalence of peri-implant mucositis, peri-implantitis and peri-implant dysbiosis. Methods During a 32-month recruitment period dental implants were assessed to diagnose healthy peri-implant tissues, mucositis or peri-implantitis. The study included 1097 implants in 196 patients. Out of all peri-implantitis cases 20 randomly chosen submucosal biofilms from implants with fixed denture (FD) originating from 13 patients and 11 biofilms from implants with removable dentures (RD) originating from 3 patients were studied for microbiome analysis. Composition of transcriptionally active biofilms was revealed by RNAseq. Metatranscriptomic profiles were created for thirty-one peri-implant biofilms suffering from peri-implantitis and microbiome changes associated with superstructure types were identified. Results 16.41% of the implants were diagnosed with peri-implantitis, 25.00% of implants with RD and 12.68% of implants with FD, respectively. Multivariate analysis showed a significant positive association on patient (p =  < 0.001) and implant level (p = 0.03) between the prevalence of peri-implantitis and RD. Eight bacterial species were associated either with FD or RD by linear discriminant analysis effect size method. However, significant intergroup confounders (e.g. smoking) were present. Conclusions Within the limitations of the present work, RDs appear to be a risk indicator for peri-implantitis and seem to facilitate expansion of specific periodontopathogens. Potential ecological and pathological consequences of shift in microbiome from RDs towards higher activity of Fusobacterium nucleatum subspecies animalis and Prevotella intermedia require further investigation.


2014 ◽  
Vol 2014 ◽  
pp. 1-6
Author(s):  
Pratik Gahalaut ◽  
Nitin Mishra ◽  
Sandhya Chauhan ◽  
Mir Mubashir Ali ◽  
Madhur Kant Rastogi ◽  
...  

Lunula is the white, half-moon shaped area seen in proximal ends of some nails. Though a few studies have described the nail changes that can occur in association with HIV infection, none of these paid much attention to lunula. Aims and Objectives. To study the lunula in fingernails among HIV infected patients. Materials and Methods. An observational, cross-sectional study to record presence of lunula in 168 HIV-positive patients and compare it with age and sex matched 168 healthy HIV-negative control. Anolunula (absence of lunula) in HIV-positive patients was correlated with CD4 counts, stages of HIV infection, time since patient was diagnosed as HIV-positive, and status of antiretroviral therapy. Results. Anolunula was present in significantly more fingernails in HIV-positive patients compared to HIV-negative controls. There was a highly significant difference for total anolunula (anolunula in all fingernails) in study and control group. Incidence of total anolunula was directly proportional to the stage of HIV infection, increasing progressively as the HIV infection advances from stage 1 to stage 4. Conclusion. Absence of lunula is related to not only HIV infection per se but also the stages of HIV infection.


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