scholarly journals Clinico-Radiological Factors Affecting Outcome of Supratentorial Spontaneous Intracerebral Hemorrhage: A Single Institute Experience

2019 ◽  
Vol 9 (1) ◽  
pp. 12-17 ◽  
Author(s):  
Nikunj Yogi ◽  
Suraj Thulung ◽  
Prakash Sharma
Keyword(s):  
Mass Effect ◽  
Intracerebral Hematoma ◽  
Continuous Variables ◽  
Midline Shift ◽  
Chi Square ◽  
Factors Affecting ◽  
Radiological Parameters ◽  
Significant Difference ◽  
Student’S T ◽  
Poor Outcomes

Introduction: Intracerebral bleeds are the second most common cause of stroke. The initial consciousness level and progressive deterioration and various radiological parameters like hematoma volume, its expansion, mass effect and location has been implicated with poor outcomes of Intracerebral Hematoma (ICH) regardless of the management methods. In this study we aimed to study various clinical and radiological parameters associated with outcome of spontaneous supratentorial ICH. Methods: This prospective study was carried out in 89 patients of spontaneous supratentorial ICH admitted to National Institute of Neurological and Allied Sciences, Nepal in between January 2015 to December 2015 to assess various parameters associated with its outcome. Outcome of the patients were assessed against various clinic-radiological and demographic variables using chi square test and student’s t test respectively for categorical and continuous variables using IBM SPSS 20 software. Results: Glasgow Coma Scale (GCS) (p=0.00), size of hematoma (p=0.034), presence of midline shift (0.000) and presence of intraventricular hematoma (p=0.020) were found to have statistically significant difference when compared in between good and poor outcome group. Conclusion: GCS at admission, size of hematoma, midline shift in cerebral tomography scan (CT scan) and presence of intraventricular hemorrhage (IVH) were significantly associated with outcome of spontaneous Supratentorial ICH.

scholarly journals Evaluation of Postoperative Pain Following Single-Visit Root Canal Treatment with Rotary and Reciprocal Ni–Ti File Systems in Children

Medicina ◽  
2021 ◽  
Vol 58 (1) ◽  
pp. 50
Author(s):  
Alp Abidin Atesci ◽  
Aslı Topaloglu-Ak ◽  
Ece Turan ◽  
Ozant Oncag ◽  
Mehmet Emin Kaval
Keyword(s):  
Postoperative Pain ◽  
Root Canal ◽  
File Systems ◽  
Pain Scale ◽  
Common Symptom ◽  
Chi Square ◽  
Factors Affecting ◽  
Single File ◽  
Significant Difference ◽  
Student’S T

Background and Objectives: Postoperative pain is a common symptom of a flare-up after root canal treatments (RCTs). Insufficient instrumentation, extrusion of irrigation solutions and debris, and the existence of a periapical lesion are the factors affecting postoperative pain after root canal treatments. The aim of this study was to evaluate the postoperative pain and instrumentation time of the single-file reciprocating system and multiple-file Ni–Ti rotary system in children ages 9–12 years old. Materials and Methods: Our study was conducted on 51 permanent mandibular molars with the diagnosis of irreversible pulpitis. Patients were randomly assigned into two groups, and RCTs were completed with either the Reciproc Blue or Protaper NEXT file systems. Instrumentation time for each system was noted, and patients were given a pain scale that included a visual analog scale for 6, 24, 48, and 72 h after treatment. Postoperative pain scores and instrumentation times were analyzed statistically with a chi-square test and Student’s t-test. Results: There was no statistically significant difference in postoperative pain between the Reciproc Blue and Protaper NEXT systems at all time intervals. Instrumentation time was significantly shorter in the Reciproc Blue group in comparison with the Protaper NEXT group. Conclusions: Postoperative pain findings following RCT using single-file reciprocating systems were similar to the rotary system group. However, chair time in the reciprocating system group was significantly lower. This provided a comfortable and patient-friendly treatment approach for children, and could enhance their cooperation.

scholarly journals 382. Difference in Pathogens Between Hip and Knee Prosthetic Joint Infection

2019 ◽  
Vol 6 (Supplement_2) ◽  
pp. S198-S198
Author(s):  
Michael Henry ◽  
Milan Kapadia ◽  
Joseph Nguyen; Barry Brause ◽  
Andy O Miller
Keyword(s):  
Prosthetic Joint Infection ◽  
Joint Infection ◽  
Categorical Variables ◽  
Continuous Variables ◽  
Chi Square ◽  
Prosthetic Joint ◽  
Significant Difference ◽  
History Of ◽  
The Difference ◽  
Student’S T

Abstract Background There is contradicting evidence characterizing the difference in pathogens that cause hip and knee prosthetic joint infection (PJI). A possible difference in microbiology may inform choice in antibiotic etiology, prophylaxis, and empiric treatment. We sought to analyze a large cohort of PJIs to see whether there was a significant difference in pathogen between joints. Methods A retrospective cohort of hip and knee PJIs, from 2008 to 2016, were identified by ICD code and surgical codes. The PJI pathogen was identified from synovial or intra-articular tissue cultures. The Student’s t-test was used to compare continuous variables. Chi-square tests were used to compare the categorical variables to joint. Results 807 PJI cases were identified including 444 knees and 363 hips. There were no significant differences between hip and knee PJIs in age, sex, history of PJI, rheumatoid arthritis, Charlson comorbidity index and laterality. There was a higher frequency of diabetes in knee PJIs (25.3%) compared with hip PJIs (15.7%), P < 0.001. No significant difference was found in the prevalence of fungal, staphylococcal (including Staphylococcus aureus), streptococcal, or enterococcal pathogens between hip and knee PJIs. Conclusion In this single-center cohort, hip and knees PJIs are infected with similar pathogens. Multiple site studies are needed to characterize the microbiology of PJIs at a larger scale. Disclosures All authors: No reported disclosures.

scholarly journals Obesity paradox in HFrEF hospitalizations: analysis of national inpatient sample 2016-2018

2021 ◽  
Vol 28 (Supplement_1) ◽  
Author(s):  
H Thyagaturu ◽  
K Shah ◽  
S Li ◽  
S Thangjui ◽  
B Shrestha ◽  
...  
Keyword(s):  
Hospital Mortality ◽  
Systolic Heart Failure ◽  
Obesity Paradox ◽  
Primary Diagnosis ◽  
Categorical Variables ◽  
Continuous Variables ◽  
National Inpatient Sample ◽  
Chi Square ◽  
Significant Difference ◽  
Student’S T

Abstract Funding Acknowledgements Type of funding sources: None. Introduction Obesity is a common and known risk factor for many cardiovascular diseases. Prior studies on chronic systolic heart failure have demonstrated that obesity is inversely associated with mortality, the so-called obesity paradox. Purpose  To study the phenomenon of obesity paradox in HFrEF hospitalizations Methods We queried January 2016 to December 2018 National Inpatient Sample (NIS) to identify adult (≥18 yrs) hospitalizations with a primary diagnosis of HFrEF. Patients with an associated diagnosis of obesity and higher BMI were also identified based on appropriate ICD-10 CM codes. We used the Chi-square test to evaluate the differences between binary or categorical variables, and Student’s t-test for continuous variables. Multivariate logistic regression was used in outcomes analysis to adjust for potential hospital and patient-level confounders. Results  We identified 639,944 weighted HFrEF hospitalizations across three years. Of which, 130,949 (20.4%) of them were associated with obesity. HFrEF with obesity hospitalizations were associated with younger age (mean age 62.0 vs 70.7 yrs; P &lt; 0.01), lesser CAD (55% vs 61%; P &lt; 0.01), higher rate of comorbidity (% of &gt;3 Elixhauser comorbidity score 99.2% vs 94.1%; P &lt; 0.01) and higher Medicaid primary payer (18.2% vs 12.7%, P &lt; 0.01). After adjusting for patient and hospital-level characteristics, we observe statistically significant difference in odds of in-hospital mortality when HFrEF with obesity hospitalizations was compared to HFrEF without obesity [Odds Ratio (OR): 1.1 (0.8 – 1.5); P = 0.52]. We observed statistically significant association with increased LOS [6.0 vs 5.3 days; P &lt; 0.01], increased total hospitalization charges [US$ 61524 vs 55677; P &lt; 0.01] and decreased coronary catheterizations [OR: 0.7 (0.5 – 0.9); P = 0.01] in HFrEF with obesity group compared to HFrEF without obesity. Conclusion In this retrospective cohort of hospitalized patients with HFrEF, higher BMI and obesity was not associated with in-hospital mortality. However, it was associated with longer LOS and higher total hospitalization charges. HFrEF with obesity hospitalizations are associated with lesser left coronary catheterizations. This may be explained by lesser burden of CAD in this patient population.

scholarly journals Comparison Of Full-Mouth Scaling and Quadrant-Wise Scaling in the Treatment of Adult Chronic Periodontitis

2018 ◽  
Vol 29 (3) ◽  
pp. 296-300 ◽  
Author(s):  
Caio Vinicius G. Roman-Torres ◽  
Matthew S. Bryington ◽  
Sergio T. Kussaba ◽  
Angelica Castro Pimentel ◽  
Ryo Jimbo ◽  
...  
Keyword(s):  
Chronic Periodontitis ◽  
Surgical Techniques ◽  
Culture Method ◽  
Biochemical Tests ◽  
Chi Square ◽  
Microbial Detection ◽  
Significant Difference ◽  
Microbiological Parameters ◽  
Chi Square Test ◽  
Student’S T

Abstract In the search for the ideal treatment of periodontal disease various non-surgical techniques should be considered. The objective of this study was to evaluate the efficacy of full-mouth scaling (FMS) by clinical and microbiological parameters. 670 individuals were evaluated with 230 subjects meeting the selection criteria and were divided into two groups; 115 subjects treated with FMS and 115 treated with weekly sessions of scaling and root planning (SRP). The patient population had a mean age of 51.67 years, with moderate chronic periodontitis. Subjects were evaluated prior to treatment (T1) and 90 days after execution of therapy (T2), with regards to: probing depth (PD), clinical attachment level (CAL), plaque index (PI), gingival index (GI), and microbial detection for the presence of Porphyromonas gingivalis (P.g.) and Prevotella intermedia (P.i.) by culture method and confirmed by biochemical tests. Subjects treated in the FMS group also rinsed with 0.12% chlorhexidine mouthwash for seven days following treatment. The results were analyzed using statistical Student’s t-test and chi-square test. No statistically significant differences were observed for PD and CAL between T1 and T2 in both groups. For GI and PI significant difference was observed between the groups. For the evaluated microbial parameters was observed reduction of P.g. and P.i., but only for P.g. with a significant reduction in both groups. The full mouth scaling technique with the methodology used in this study provided improved clinical conditions and reduction of P.g. in subjects with moderate periodontitis, optimizing the time spent in the therapeutic execution.

Incidence of adverse drug reactions induced by N-acetylcysteine in patients with acetaminophen overdose

2010 ◽  
Vol 29 (3) ◽  
pp. 153-160 ◽  
Author(s):  
Sa'ed H Zyoud ◽  
Rahmat Awang ◽  
Syed Azhar Syed Sulaiman ◽  
Waleed M Sweileh ◽  
Samah W Al-jabi
Keyword(s):  
Adverse Drug Reactions ◽  
Univariate Analysis ◽  
Drug Reactions ◽  
Chi Square ◽  
Exact Test ◽  
Acetaminophen Overdose ◽  
Significant Difference ◽  
Chi Square Test ◽  
Comparative Results ◽  
Student’S T

Background: Intravenous N-acetylcysteine (IV-NAC) is widely recognized as the antidote of choice for acetaminophen overdose. However, its use is not without adverse drug reactions (ADR) that might affect therapeutic outcome or lead to treatment delay. Objective: the aim of this study was to investigate the type and incidence of ADR induced by IV-NAC in patients treated for acetaminophen overdose. Methods: This is a retrospective study of patients admitted to the hospital for acute acetaminophen overdose over a period of 4 years (1 January 2005 to 31 December 2008). The primary outcome of interest in this study was the occurrence of ADR during NAC administration. Pearson chi-square test or Fisher’s exact test, student’s t test, and Mann-Whitney U test were used in univariate analysis. SPSS 15 was used for data analysis. Results: Two hundred and fifty five patients were studied. Different types of ADR were observed in 119 (46.7%) cases. Of those patients, 83 (69.7%) had been treated with IV-NAC versus 36 (30.3%) who had not (p < .001). The following ADR were significantly associated with IV-NAC administration: vomiting (p = .001), flushing (p < .001), rash (p < .001), pruritus (p < .001), chest pain (p = .001), bronchospasm (p = .03), coughing (p = .01), headache (p = .001), dizziness (p < .001), convulsion (p = .03), and hypotension (p = .001). ADR were mild in 54 (43.2%), moderate in 17 (13.6%), and severe in 12 (9.6%) patients. There were no ADR in 42 (33.6%) patients. Comparative results of the characteristics of patients who reacted to IV-NAC and nonreactors showed that patients with ADR had no significant difference in age, gender, ethnicity, amount ingested, latency time, and acetaminophen level than nonreactors. Conclusion: ADR to IV-NAC were common among patients with acetaminophen overdose, but mostly minor and all reported adverse reactions were easily managed.

Can racial and financial disparities be overcome in the surgical treatment of NSCLC?

2013 ◽  
Vol 31 (31_suppl) ◽  
pp. 208-208
Author(s):  
Jordan R. Sasson ◽  
Gary Schwartz ◽  
Sadiq Rehmani ◽  
Hassan S Moghaddas ◽  
Sarah Almubarak ◽  
...  
Keyword(s):  
Induction Therapy ◽  
Categorical Variables ◽  
Continuous Variables ◽  
Urban Hospital ◽  
Chi Square ◽  
Black Patients ◽  
Diverse Patient Population ◽  
Chi Square Test ◽  
Student’S T ◽  
Nsclc Patients

208 Background: Considerable data exists examining disparities in the treatment of non-small cell lung cancer (NSCLC) patients. Black patients, in particular those of lower socioeconomic status (SES), are less likely to receive appropriate care, including induction therapy and resection of surgically treatable lesions. We analyzed the outcomes of resection of NSCLC among a racially and financially diverse patient population at a large urban hospital network with a comprehensive thoracic oncology program. In this system, a patient navigation support team helped overcome barriers to preoperative preparation and multidisciplinary referral. Methods: A retrospective review of 345 patients who underwent lobectomy at our institution from 2002 - 2011 was performed. Data was retrieved from the Society of Thoracic Surgeons (STS) database and patient charts. Patient demographics, payor information and preoperative characteristics were noted. Postoperative complications, 30-day survival and 3-year survival were compared. Statistical analysis was performed using SPSS 17.0 (SPSS Inc, Chicago, IL). Chi-square test was used to compare categorical variables and Student's t-test was used to compare continuous variables. Results: Demographics of black and non-black patients were similar. There were more black patients within the Medicaid group than non-Medicaid (48.9% and 25.3%, p=0.001). Physiologic characteristics, risk factors and use of pre-operative RT and chemotherapy were similar. Post-operative complications were comparable in Medicaid vs. non-Medicaid (11.1% and 14.7%, p=0.524), however black patients had a lower rate of complications vs. non-black (6.1% and 17.4%, p=0.007). 3-year survival was similar in the black vs. non-black (82.3% and 78.6%, p=0.879) and Medicaid vs. non-Medicaid (66.7% and 78.8%, p=0.342) groups. Conclusions: We demonstrated equivalent surgical outcomes for NSCLC in addition to the similar use of induction therapy. Surprisingly, complications were lower in the black cohort. Our results reveal that appropriate treatment is being provided regardless of race or SES, and postulate that our system of preoperative patient support eliminates potential barriers to care.

scholarly journals Assessment of first molars sagittal and rotational position in Class II, division 1 malocclusion

2013 ◽  
Vol 18 (6) ◽  
pp. 106-111 ◽  
Author(s):  
Paulo Estevão Scanavini ◽  
Renata Pilli Jóias ◽  
Maria Helena Ferreira Vasconcelos ◽  
Marco Antonio Scanavini ◽  
Luiz Renato Paranhos
Keyword(s):  
Class Ii ◽  
Chi Square ◽  
Mean Values ◽  
Significance Level ◽  
Significant Difference ◽  
Division 1 ◽  
Chi Square Test ◽  
Student’S T ◽  
The Right ◽  
Class Ii Division 1

OBJECTIVE: This study assessed the anterior-posterior positioning of the upper and lower first molars, and the degree of rotation of the upper first molars in individuals with Class II, division 1, malocclusion. METHODS: Asymmetry I, an accurate device, was used to assess sixty sets of dental casts from 27 females and 33 males, aged between 12 and 21 years old, with bilateral Class II, division 1. The sagittal position of the molars was determined by positioning the casts onto the device, considering the midpalatal suture as a symmetry reference, and then measuring the distance between the mesial marginal ridge of the most distal molar and the mesial marginal ridge of its counterpart. With regard to the degree of rotation of the upper molar, the distance between landmarks on the mesial marginal ridge was measured. Chi-square test with a 5% significance level was used to verify the variation in molars position. Student's t test at 5% significance was used for statistical analysis. RESULTS: A great number of lower molars mesially positioned was registered, and the comparison between the right and left sides also demonstrated a higher number of mesially positioned molars on the right side of both arches. The average rotation of the molars was found to be 0.76 mm and 0.93 mm for the right and left sides, respectively. CONCLUSION: No statistically significant difference was detected between the mean values of molars mesialization regardless of the side and arch. Molars rotation, measured in millimeters, represented ¼ of Class II.

Does Gender Influence How Patients Rate Their Patient Experience after Total Knee Arthroplasty?

2017 ◽  
Vol 30 (07) ◽  
pp. 634-638 ◽  
Author(s):  
Marcelo Siqueira ◽  
Morad Chughtai ◽  
Anton Khlopas ◽  
Chukwuweike Gwam ◽  
Jaydev Mistry ◽  
...  
Keyword(s):  
Total Knee Arthroplasty ◽  
Patient Experience ◽  
Knee Arthroplasty ◽  
Pay For Performance ◽  
Continuous Variables ◽  
Chi Square ◽  
Men And Women ◽  
Significant Difference ◽  
Total Knee ◽  
Chi Square Analysis

AbstractThe Centers for Medicare and Medicaid Services has implemented the Value-Based Purchasing (VBP) score as a pay-for-performance reimbursement model. Patient experience, as measured by the Press Ganey (PG) survey, currently comprises 20% of total VBP score. It is therefore beneficial for the orthopaedist to become familiar with these changes to maximize profits. Currently, a paucity of data exists that elucidates which factors influence PG scores between men and women following total knee arthroplasty (TKA). Therefore, we asked: (1) which PG survey factors most influences hospital ratings among men and women patients post-TKA and (2) is there a significant difference in overall hospital ratings among men and women cohorts post-TKA? We queried the PG database for patients who received a TKA between November 2009 and January 2015, yielding 224 men (mean age 64 years, range: 39–88) and 519 women (mean age 65 years; range, 25–92). A multiple regression analysis was performed for each cohort with overall hospital satisfaction as the dependent variable to assess the influence (β-weight) each PG domain imparted on overall hospital rating. A chi-square analysis and t-test were performed to assess categorical and continuous variables, respectively. For men, communication with nurses (β = 0.408, p = 0.016), followed by communication about medications (β = 0.261, p = 0.032), most influenced overall hospital rating. For women, communication with nurses (β = 0.479, p < 0.001) most influenced overall hospital rating. This was followed by staff responsiveness (β = 0.201, p = 0.046), pain management (β = 0.263, p = 0.015), and communication about medications (β = − 0.152, p = 0.029). It is of great advantage for the orthopaedist to focus on the PG domains most pertinent to each patient gender post-TKA. For both genders, overall hospital rating was significantly influenced by communication with nurses and information about medication. However, staff responsiveness and pain control were of significant importance in determining overall hospital rating for women. Therefore, orthopaedists should consider focusing on these factors depending on the gender of the patient to optimize satisfaction.

scholarly journals Evaluation of the dentin changes in teeth subjected to endodontic treatment and photodynamic therapy

2016 ◽  
Vol 45 (6) ◽  
pp. 339-343
Author(s):  
Mariane Floriano Lopes Santos LACERDA ◽  
Carolina Oliveira de LIMA ◽  
Gabriel Pinheiro LACERDA ◽  
Celso Neiva CAMPOS
Keyword(s):  
Photodynamic Therapy ◽  
Morphological Changes ◽  
Chi Square ◽  
Dentinal Tubules ◽  
Level Laser ◽  
Significant Difference ◽  
Root Dentin ◽  
Root Canal System ◽  
Student’S T ◽  
Apical Leakage

Abstract Introduction Antimicrobial photodynamic therapy (PDT) is an efficient adjuvant technique to promote disinfection of the root canal system. Therefore, it is important to investigate changes to dentin morphology and permeability induced by the use of diode laser on the root dentin. Objective The purpose of this study was to investigate morphological changes and the percentage of apical leakage after the use of laser. Material and method Forty single-rooted teeth were instrumented using rotary system and irrigated. Teeth were randomly divided in two groups: G1 - not exposed to PDT (control), and G2 - pretreated with toluidine blue photosensitizer and irradiated with AsGaAl laser diode. Ten teeth in each group were evaluated by SEM for morphological changes. The other ten teeth were filled and stained with Rhodamine B to evaluate the apical leakage. Result The results showed significant difference between G1 and G2 (p <0.001 - chi-square), with greater presence of debris in G1 and higher incidence of open dentinal tubules in G2. Erosions and cracks were observed in both groups, with no statistically significant difference (p> 0.001). The apical leakage was significantly higher in G2 than in G1 (p <0.001 - Student's t-test). Conclusion It was concluded that the use of low-level laser reduced the smear layer and opened the dentinal tubules. Use of laser increased the permeability of the apical dentin.

scholarly journals POLA KONSUMSI SUMBER PURIN, AKTIVITAS FISIK DAN STATUS GIZI DENGAN KADAR ASAM URAT PADA LANSIA DI PUSKESMAS KECAMATAN MAKASAR JAKARTA

2020 ◽  
Vol 4 (1) ◽  
pp. 84
Author(s):  
Gina Ganda Fitriana ◽  
Adhila Fayasari
Keyword(s):  
Physical Activity ◽  
Uric Acid ◽  
Nutritional Status ◽  
Uric Acid Level ◽  
Acid Level ◽  
Consumption Pattern ◽  
Chi Square ◽  
Cross Sectional ◽  
Factors Affecting ◽  
Significant Difference

Degenerative processes can decrease the endurance in elderly that leads to health problem such as gout. Gout is a metabolic disorder, which is indicated by an increase uric acid in bloodstream (hyperuricemia). Factors affecting high level of uric acid are purine intake, physical activity and nutritional status. The aim of this study was to analyze the relationship between consumption pattern of purine source food, nutritional status and physical activity with uric acid level in elderly. The study design was cross sectional. The sample consisted of 100 subyekts at Puskesmas Kecamatan Makasar. The analytical used chi square. Patterns of food consumption of purine sources were measured using FFQ questionnaires which was then cut off into into 2 categories: low-moderate purine category with score <55 and high purine category with a score of ≥55 physical activity and nutritional status were measured using questionnaires, uric acid levels was obtained by looking at laboratory results or from patients' medical records. There was 10% of subyekts withlo- moderate uric acid levels and 90% of subyekts with high purine consumption pattern. Based on the results of chi square test there was a significant difference (p <0.05) between the consumption pattern of purine source food with normal uric acid and high uric acid. There was a relationship between consumption pattern of purine food source with uric acid level in elderly.

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