Characteristics of the epidemiological situation of mumps in the world atthe present stage

2021 ◽  
Vol 20 (2) ◽  
pp. 74-82
Author(s):  
N. V. Turaeva ◽  
R. A. Frolov ◽  
O. V. Tsvirkun ◽  
A. G. Gerasimova
Keyword(s):  
Young Adults ◽  
Reproductive Function ◽  
Conclusive Evidence ◽  
Mmr Vaccine ◽  
High Coverage ◽  
Economic Significance ◽  
Literary Sources ◽  
The World ◽  
Previous Infection ◽  
Epidemic Parotitis

Relevance. The socio-economic significance of mumps is determined by complications after a previous infection, affecting reproductive function, what entails economic and demographic losses. An important problem today remains the fact that despite high coverage with preventive vaccinations outbreaks of mumps are recorded among children and young adults. Aim. Analyze the epidemic situation with epidemic parotitis in the world according to various literary sources and evaluate measures to control and combat this infection. Conclusions. Outbreaks of mumps have been reported among religious and ethnic groups. Outbreaks were often recorded in organized student and military groups, mainly among persons twice vaccinated. The most affected by the mumps virus were adolescents and young adults, mostly males. Several researchers have shown the possibility of using a third dose of MMR vaccine to control an outbreak, but its short-term effect does not provide conclusive evidence for rethinking two-dose mumps immunization.

Acceptability of HIV testing for adolescents and young adults by delivery model: a systematic review

2021 ◽  
pp. jim-2021-002056
Author(s):  
Peter Thomas Leistikow ◽  
Vidhi Patel ◽  
Christian Nouryan ◽  
Joseph Steven Cervia
Keyword(s):  
Young Adults ◽  
North America ◽  
Care Delivery ◽  
Linkage To Care ◽  
Adolescents And Young Adults ◽  
Hiv Screening ◽  
Model Of Care ◽  
Delivery Model ◽  
Care Delivery Model ◽  
The World

HIV infections are prevalent among adolescents and young adults, of whom 44% remain unaware of their diagnosis. HIV screening presents numerous challenges including stigma, fear, and concerns about confidentiality, which may influence young people’s acceptance of HIV screening and linkage to care differently from individuals in other age groups. It is imperative to understand which care delivery models are most effective in facilitating these services for youth. This systematic review analyzes the rates of HIV test acceptance and linkage to care by care delivery model for adolescents and young adults. Studies were classified into emergency department (ED), primary care/inpatient setting, community-based program, or sexually transmitted infection clinic models of care. From 6395 studies initially identified, 59 met criteria for inclusion in the final analyses. Rate of test acceptance and linkage to care were stratified by model of care delivery, gender, race, age ranges (13–17, 18–24 years) as well as site (North America vs rest of the world). A significant difference in acceptance of HIV testing was found between care models, with high rates of test acceptance in the ED setting in North America and primary care/hospital setting in the rest of the world. Similarly, linkage to care differed by model of care, with EDs having high rates of linkages to HIV care in North America. Future studies are needed to test mechanisms for optimizing outcomes for each care delivery model in addressing the unique challenges faced by adolescents and young adults.

scholarly journals Scleractinian corals from the Upper Cretaceous and Lower Tertiary of Nûgssuaq, West Greenland

1972 ◽  
Vol 100 ◽  
pp. 1-132
Author(s):  
S Floris
Keyword(s):  
Upper Cretaceous ◽  
Reef Coral ◽  
Conclusive Evidence ◽  
New Genera ◽  
Generic Level ◽  
West Greenland ◽  
North West ◽  
Fossil Corals ◽  
The World ◽  
Marine Fossils

Localities and deposits in north-west Nûgssuaq yielding fossil corals of the order Scleractinia are described. The age of the corals is Campanian?, Maastrichtian and Lower Paleocene (Danian), on the basis of other marine fossils. 22 species are considered; 7 are described as new and are indigenous, 2 are possibly North American forms, 3 are known from Europe, and 10 are identifiable only to generic level. The following genera and subgenera are represented: Haimesiastraea (Haimesiastraea), H. (Perupiastrea)?, Discotrochus?, Astrangia (Coenangia)?, Oculina, Caryophyllia, Trochocyathus, Paracyathus, Stephanocyathus (Stephanocyathus), Desmophyllum?, Lophelia?, Parasmilia, Flabellum, Balanophyllia, and Dendrophyllia . In addition, two new genera are described: Kangiliacyathus and Faksephyllia . Certain Danian corals from Scandinavia are also revised. In a survey of habitats, the lithology of the corallocalities is considered together with bathymetric and thermal ranges known for scleractinian genera and species from other parts of the world. Depth and temperature of the Campanian and Maastrichtian seas in Greenland cannot be estimated with any accuracy. The Lower and Upper Danian seas were generally rather shallow. There is little evidence on which to judge the Danian climate. Two species were perhaps hermatypic (no reef structures have been found). The remaining scleractinians are presumed to have been ahermatypic. A non-reef coral association has been found. Lower Danian rather sparsely populated polytypic coral thickets show signs of continual disturbance from water turbulence. The approximate depth of formation of these thickets appears to have been 80 m or shallower, which appears to be less than is usual for coral structures of this type. Some Lower Paleocene species provide conclusive evidence of a direct connection between the Danian seas of West Greenland and of Scandinavia.

scholarly journals A SINGLE CASE STUDY ON THE EFFECT OF AYURVEDIC MANAGEMENT IN TIMIRA W.S.R. TO MYOPIA – A CASE STUDY

2021 ◽  
Vol 9 (7) ◽  
pp. 1549-1554
Author(s):  
Kavita Rathore ◽  
Shamsa Fiaz
Keyword(s):  
Visual Acuity ◽  
Young Adults ◽  
Single Case ◽  
Single Case Study ◽  
Anatomical Structures ◽  
The World ◽  
Chief Complaints ◽  
Children And Young Adults ◽  
Defective Vision

Introduction - Myopia is the most common Refractive error of the eye seen in children and young adults and it has become more prevalent in recent years and is a cause of concern the world over. Myopia commonly referred to as near or shortsightedness. Some of the clinical features of Vataja Timira can be correlated with Myopia. Timira is counted under the Drishtigata Rogas [1] described by Sushruta. Timira involving first and second patala in terms of symptoms, anatomical structures involved and the pathogenesis of the disease. Timira begins with the blurring of vision gradually leading to the deterioration of eyesight. Shastrokta lakshanas of Vatika Timira such as bhramantiva sa pashyati, aavil darshan, vyaavidha darshan, aruna darshan [2]. Materials and Methods - A 20-year-old male, came to Shalakya Tantra OPD in National Institute of Ayurveda, deemed to be University Jaipur (R.J.), with chief complaints of defective vision for distance in both eyes, pain in both eyes and watering from both eyes since 4 months. He was treated with Nasya, Netra Pariseka, one sitting of Tarpana, Triphala guggulu, Patoladi eyedrops and Netramritam eyedrops. Result - At the end of the study, improvement in the visual acuity in both eyes, improvement in pain in both eyes and watering from both eyes have reduced. Conclusion -Thus, it can be concluded that Ayurvedic treatments are helpful to control Myopia. Keywords: Myopia, Nasya, Tarpana, Netra pariseka, Timira, Triphala Guggulu.

Clinical trials of COVID 19 vaccines and vaccination campaign: ethical issues

2021 ◽  
Author(s):  
VE Goncharova
Keyword(s):  
Clinical Trials ◽  
Preventive Measures ◽  
Ethical Issues ◽  
Vaccine Development ◽  
Vaccination Campaign ◽  
Public Confidence ◽  
Basic Principles ◽  
Literary Sources ◽  
The World ◽  
Decisive Action

For many centuries, infectious diseases have posed a serious threat: epidemics and pandemics claim lives and multiply the burden on health systems and countries' economies. Humanity managed to defeat a number of infections only thanks to specific preventive measures, i.e., vaccination. In 2020, society faced the new COVID-19 virus that has swept the whole world. The situation required swift and decisive action, including in what concerned vaccine development. It has also raised a number of ethical issues. The article analyzes ethical issues related to clinical trials and vaccination against COVID-19 by studying the regulations, literary sources and bioethical incidents. The key problems identified are: human participation in clinical trials during a pandemic, availability and, simultaneously, voluntariness of vaccination, public confidence in the SARS-Cov-2 vaccines approved for clinical practice. The study showed that the basic principles of clinical trials, voluntariness and awareness, are violated. It was revealed that despite all the efforts of public organizations and WHO initiatives in the world, there is a pronounced imbalance in the availability of the developed vaccines, while the vaccination voluntariness principle is violated by application of various mechanisms to put pressure on people, and public confidence in the developed vaccines can be called insufficient. In general, the problem of vaccination against COVID-19 remains relevant and requires comprehensive discussion.

scholarly journals State of vaccine confidence in the European Union in 2018

2019 ◽  
Vol 29 (Supplement_4) ◽  
Author(s):  
H Larson ◽  
A de Figueiredo ◽  
E Karafllakis ◽  
M Rawal
Keyword(s):  
European Union ◽  
Czech Republic ◽  
Vaccine Hesitancy ◽  
The European Union ◽  
Mmr Vaccine ◽  
High Coverage ◽  
Member States ◽  
The Public ◽  
Eu Member States ◽  
Vaccine Confidence

Abstract Background High confidence in vaccination programmes is crucial for maintaining high coverage rates. Across the European Union (EU), however, vaccine delays and refusals are contributing to declining immunisation rates in a number of countries and are leading to increases in disease outbreaks. Methods We assessed the overall state of confidence in vaccines among the public in all 28 EU member states and among general practitioners (GP) in ten EU member states, conducting the largest ever study on attitudes to vaccines and vaccination in the EU, eliciting the views of approximately 28,000 respondents across the 28 EU member states. Results We found that a number of member states (including France, Greece, Italy, and Slovenia) have become more confident in the safety of vaccines since 2015, but that the Czech Republic, Finland, Poland, and Sweden have become less confident. While GPs generally hold higher levels of vaccine confidence than the public, the survey found that 36% of GPs surveyed in Czech Republic and 25% in Slovakia do not agree that the MMR vaccine is safe and 29% and 19% respectively do not believe it is important. Countries whose GPs hold higher confidence in vaccines tend to have a larger proportion of the public expressing positive vaccination beliefs. Conclusions Even countries with well-established vaccination programmes and high levels of confidence are not immune to rising vaccine hesitancy. There is a need for continuous monitoring, preparedness and response plans to maintain and increase confidence in the importance, effectiveness and safety of vaccines, among both the public and health professionals.

scholarly journals Occurence of Fusarium Mycotoxins in Wheat from Europe – A Review

2015 ◽  
Vol 19 (1) ◽  
pp. 35-60 ◽  
Author(s):  
Oana Stanciu ◽  
Roxana Banc ◽  
Anamaria Cozma ◽  
Lorena Filip ◽  
Doina Miere ◽  
...  
Keyword(s):  
World Wide ◽  
Fusarium Species ◽  
Animal Health ◽  
Animal Nutrition ◽  
Fungal Metabolites ◽  
Substrate Type ◽  
Fusarium Mycotoxins ◽  
Economic Significance ◽  
The World

AbstractThe quality of cereals is very important for both human and animal nutrition. Fusarium mycotoxins include a great number of compounds. Trichothecenes, zearalenone (ZEN) and fumonisins are the major Fusarium mycotoxins occurring in cereal grains, animal feeds and forages. Conditions that predispose to mycotoxin production by Fusarium species include humidity, temperature, aeration and substrate type. Even if a great number of fungal metabolites have been designated as mycotoxins, a small number are known to have significant animal/human health and economic significance. For this, the world-wide impact of mycotoxins on human and animal health is likely underestimated and the future in this area is to identify additional specific biomarkers and group of biomarkers that can be used to establish the exposition of human and animals to individual mycotoxins.

Ut musica poesis: Music and Poetry in France in the Late Sixteenth Century

1994 ◽  
Vol 13 ◽  
pp. 1-63 ◽  
Author(s):  
Howard Mayer Brown
Keyword(s):  
Sixteenth Century ◽  
Subject Matter ◽  
Ancient Greece ◽  
World Order ◽  
Pierre De Ronsard ◽  
Ideal Form ◽  
Literary Sources ◽  
The World ◽  
The Subject ◽  
Crucial Part

By praising rulers, whose magnificence formed a crucial part of the world order, Pierre de Ronsard and his French colleagues in the second half of the sixteenth century often depicted the world not as it was but as it ought to be. This idea informs Margaret McGowan's book on ideal forms in the age of Ronsard, in which she explores the ways poets and painters extolled the virtues and the theatrical magnificence of perfect princes following the Horatian dictum ut pictura poesis: as is painting so is poetry. McGowan demonstrates the virtuosity of the painters and poets of the sixteenth century in shaping their hymns of praise from the subject matter and ideals of ancient Greece and Rome by following Horace's advice to regard paintings as mute poems and poems as speaking pictures. McGowan shows how artists and intellectuals pursued their goals by creating four kinds of ideal form: iconic forms, sacred images derived from classical literary sources offering princes some guarantee of immortality; triumphal forms that evoke the heroic imperial past; ideal forms of beauty to be found in contemplating the beloved; and dancing forms that mirror rituals of celebration. McGowan claims that such ideal forms were intended to enlighten the ruler himself as much as they celebrated his grandeur in the eyes of others.

Modelling the population-level impact of vaccination on the transmission of human papillomavirus type 16 in Australia

Sexual Health ◽  
2007 ◽  
Vol 4 (3) ◽  
pp. 147 ◽  
Author(s):  
David G. Regan ◽  
David J. Philp ◽  
Jane S. Hocking ◽  
Matthew G. Law
Keyword(s):  
Human Papillomavirus ◽  
Cost Effectiveness ◽  
Hpv Infection ◽  
Conclusive Evidence ◽  
Effective Vaccine ◽  
High Coverage ◽  
Hpv 16 ◽  
Highly Effective ◽  
Catch Up ◽  
The Impact

Background: Vaccines are now available to prevent the development of cervical cancer from genital human papillomavirus (HPV) infection. The decision to vaccinate depends on a vaccine’s cost-effectiveness. A rigorous cost-effectiveness model for vaccinated individuals is presented in a companion paper; this paper investigates the additional benefits the community might receive from herd immunity. Methods: A mathematical model was developed to estimate the impact of a prophylactic vaccine on transmission of HPV type 16 in Australia. The model was used to estimate the expected reduction in HPV incidence and prevalence as a result of vaccination, the time required to achieve these reductions, and the coverage required for elimination. The modelled population was stratified according to age, gender, level of sexual activity and HPV infection status using a differential equation formulation. Clinical trials show that the vaccine is highly effective at preventing persistent infection and pre-cancerous lesions. These trials do not, however, provide conclusive evidence that infection is prevented altogether. The possible modes of vaccine action were investigated to see how vaccination might change the conclusions. Results: The model predicts that vaccination of 80% of 12-year-old girls will eventually reduce HPV 16 prevalence by 60–100% in vaccinated and 7–31% in unvaccinated females. If 80% of boys are also vaccinated, reductions will be 74–100% in vaccinated and 86–96% in unvaccinated females. A campaign covering only 12-year-old girls would require 5–7 years to achieve 50% of the eventual reduction. With a catch-up campaign covering 13–26-year-olds, this delay would be reduced to only 2 years. Unrealistically high coverage in both sexes would be required to eliminate HPV 16 from the population. Under pessimistic assumptions about the duration of vaccine-conferred immunity, HPV 16 incidence is predicted to rise in some older age groups. Conclusions: Mass vaccination with a highly effective vaccine against HPV 16 has the potential to substantially reduce the incidence and prevalence of infection. Catch-up vaccination offers the potential to substantially reduce the delay before the benefits of vaccination are observed. A booster vaccination might be required to prevent an increase in incidence of infection in women over 25 years of age.

scholarly journals A Spatial Agent-Based Model to Assess the Spread of Malaria in Relation to Anti-Malaria Interventions in Southeast Iran

2020 ◽  
Vol 9 (9) ◽  
pp. 549
Author(s):  
Navid Mahdizadeh Gharakhanlou ◽  
Navid Hooshangi ◽  
Marco Helbich
Keyword(s):  
Indoor Residual Spraying ◽  
Intervention Strategies ◽  
Agent Based Model ◽  
Malaria Endemic Area ◽  
High Coverage ◽  
Agent Based ◽  
The World ◽  
Coverage Rates ◽  
Long Lasting Insecticidal Nets ◽  
Malaria Interventions

Malaria threatens the lives of many people throughout the world. To counteract its spread, knowledge of the prevalence of malaria and the effectiveness of intervention strategies is of great importance. The aim of this study was to assess (1) the spread of malaria by means of a spatial agent-based model (ABM) and (2) the effectiveness of several interventions in controlling the spread of malaria. We focused on Sarbaz county in Iran, a malaria-endemic area where the prevalence rate is high. Our ABM, which was carried out in two steps, considers humans and mosquitoes along with their attributes and behaviors as agents, while the environment is made up of diverse environmental factors, namely air temperature, relative humidity, vegetation, altitude, distance from rivers and reservoirs, and population density, the first three of which change over time. As control interventions, we included long-lasting insecticidal nets (LLINs) and indoor residual spraying (IRS). The simulation results showed that applying LLINs and IRS in combination, rather than separately, was most efficient in reducing the number of infected humans. In addition, LLINs and IRS with moderate or high and high coverage rates, respectively, had significant effects on reducing the number of infected humans when applied separately. Our results can assist health policymakers in selecting appropriate intervention strategies in Iran to reduce malaria transmission.

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