scholarly journals Assessment of Photoplethysmography Method in Extraction of Hemoglobin Concentration

2018 ◽  
Author(s):  
M Azarnoosh ◽  
H Doostdar
Keyword(s):  
Negative Correlation ◽  
Pearson Correlation ◽  
Rank Correlation ◽  
Hemoglobin Concentration ◽  
Optical Methods ◽  
Non Invasive ◽  
Pearson Coefficient ◽  
Signal Peak ◽  
Standard Pulse ◽  
Peak Value

Background: The importance of continuous monitoring along with rapid and accurate notification of changes in blood components such as hemoglobin concentration, especially in acute situations, encourages researchers to use non-invasive methods for measuring.Objective: This study was aimed to investigate the correlation between hemoglobin concentration and photoplethysmogram (PPG) and the possibility of measuring it by an optical method.Material and Methods: In this applied study, a PPG signal was simultaneously recorded at four different wavelengths for thirty subjects who were referred to the laboratory for a hemoglobin concentration test. After calibrating the special recording probe with a standard pulse oximeter system and applying the required preprocessing on the obtained signals, the peak-to-peak value of PPG signals was extracted. Finally, the correlation between the peak-to-peak value of the signal at a certain wavelength and hemoglobin concentration was analyzed using Spearman and Pearson correlation for determining the process of changes in the data.Results: The results demonstrated that based on the normal distribution of data at 590 nm wavelength, there is a significantly negative correlation between a function of the signal peak slope and the hemoglobin concentration, with a Pearson coefficient of -0.787 (p<0.01). In addition, the investigation of rank correlation indicated a significantly negative correlation of -0.842 (p<0.01) using Spearman correlation analysis.Conclusion: Considering the high correlation between hemoglobin concentration and PPG signal characteristics, optical methods can be used to develop a rapid, precise, clean and inexpensive method to measure hemoglobin concentration.

scholarly journals Korelasi kadar hemoglobin dengan saturasi oksigen pada guru besar Universitas Padjadjaran

2018 ◽  
Vol 1 (2) ◽  
pp. 26-29
Author(s):  
Della Suherlim ◽  
Leonardo Lubis ◽  
Hikmat Permana
Keyword(s):  
Oxygen Saturation ◽  
Aging Process ◽  
Pearson Correlation ◽  
Rank Correlation ◽  
Secondary Data ◽  
Hemoglobin Concentration ◽  
The Elderly ◽  
Hemoglobin Level ◽  
Cellular Damage ◽  
Correlation Test

Background: The aging process is recognizable through bodily functions dicreases caused by molecular and cellular damage. Elderly is the most affected population by this aging process, such as the majority of professors in Universitas Padjadjaran. In elderly, that tissue oxigenation is trend to decrease due to reduction of both hemoglobin level and oxygen saturation. Aim: This study aimed to find out correlation between hemoglobin level and oxygen saturation in the elderly professors of Universitas Padjadjaran. Method: This study analyzed secondary data from health check-up result of the professors. 108 data of the professors met the inclusion criteria and were used in this study. This data underwent the normality test ( Male = 84 subjects, using the Kolmogorov-Smirnov test. Female = 24 subjects, using Shapiro-Wilk test.). Spearman’s Rank correlation test was used for total subjects and male professors group, while Pearson correlation test was used for female professors group. Results: Correlation test between hemoglobin concentration and oxygen saturation resulted in an insignificant result in male professors (r = 0.028 ; p = 0.801; z = 0.200 ; 0.00 ), female professors (r = 0.132; p = 0.538; z = 0.582; 0.272), and also in total subjects (r = 0.036; p = 0.712; z = 0.200; 0.00 ). Conclusion: There is no correlation between hemoglobin concentration and oxygen saturation in the elderly professors of Universitas Padjadjaran.

Relationship between Invasive and Non-Invasive Hemodynamic Measures in Experimental Pulmonary Hypertension

2020 ◽  
Vol 16 (1) ◽  
pp. 47-53
Author(s):  
Vicente Benavides-Córdoba ◽  
Mauricio Palacios Gómez
Keyword(s):  
Heart Rate ◽  
Pulmonary Hypertension ◽  
Ejection Fraction ◽  
Right Ventricle ◽  
Correlation Coefficient ◽  
Pearson Correlation ◽  
Systolic Pressure ◽  
Control Group ◽  
Pearson Correlation Coefficient ◽  
Non Invasive

Introduction: Animal models have been used to understand the pathophysiology of pulmonary hypertension, to describe the mechanisms of action and to evaluate promising active ingredients. The monocrotaline-induced pulmonary hypertension model is the most used animal model. In this model, invasive and non-invasive hemodynamic variables that resemble human measurements have been used. Aim: To define if non-invasive variables can predict hemodynamic measures in the monocrotaline-induced pulmonary hypertension model. Materials and Methods: Twenty 6-week old male Wistar rats weighing between 250-300g from the bioterium of the Universidad del Valle (Cali - Colombia) were used in order to establish that the relationships between invasive and non-invasive variables are sustained in different conditions (healthy, hypertrophy and treated). The animals were organized into three groups, a control group who was given 0.9% saline solution subcutaneously (sc), a group with pulmonary hypertension induced with a single subcutaneous dose of Monocrotaline 30 mg/kg, and a group with pulmonary hypertension with 30 mg/kg of monocrotaline treated with Sildenafil. Right ventricle ejection fraction, heart rate, right ventricle systolic pressure and the extent of hypertrophy were measured. The functional relation between any two variables was evaluated by the Pearson correlation coefficient. Results: It was found that all correlations were statistically significant (p <0.01). The strongest correlation was the inverse one between the RVEF and the Fulton index (r = -0.82). The Fulton index also had a strong correlation with the RVSP (r = 0.79). The Pearson correlation coefficient between the RVEF and the RVSP was -0.81, meaning that the higher the systolic pressure in the right ventricle, the lower the ejection fraction value. Heart rate was significantly correlated to the other three variables studied, although with relatively low correlation. Conclusion: The correlations obtained in this study indicate that the parameters evaluated in the research related to experimental pulmonary hypertension correlate adequately and that the measurements that are currently made are adequate and consistent with each other, that is, they have good predictive capacity.

scholarly journals Non-invasive diffuse optical neuromonitoring during cardiopulmonary resuscitation predicts return of spontaneous circulation

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Tiffany S. Ko ◽  
Constantine D. Mavroudis ◽  
Ryan W. Morgan ◽  
Wesley B. Baker ◽  
Alexandra M. Marquez ◽  
...  
Keyword(s):  
Cardiac Arrest ◽  
Cardiopulmonary Resuscitation ◽  
Hemoglobin Concentration ◽  
Spontaneous Circulation ◽  
Youden Index ◽  
Swine Model ◽  
Return Of Spontaneous Circulation ◽  
Non Invasive ◽  
Tissue Optical Properties ◽  
Tenfold Cross Validation

AbstractNeurologic injury is a leading cause of morbidity and mortality following pediatric cardiac arrest. In this study, we assess the feasibility of quantitative, non-invasive, frequency-domain diffuse optical spectroscopy (FD-DOS) neuromonitoring during cardiopulmonary resuscitation (CPR), and its predictive utility for return of spontaneous circulation (ROSC) in an established pediatric swine model of cardiac arrest. Cerebral tissue optical properties, oxy- and deoxy-hemoglobin concentration ([HbO2], [Hb]), oxygen saturation (StO2) and total hemoglobin concentration (THC) were measured by a FD-DOS probe placed on the forehead in 1-month-old swine (8–11 kg; n = 52) during seven minutes of asphyxiation followed by twenty minutes of CPR. ROSC prediction and time-dependent performance of prediction throughout early CPR (< 10 min), were assessed by the weighted Youden index (Jw, w = 0.1) with tenfold cross-validation. FD-DOS CPR data was successfully acquired in 48/52 animals; 37/48 achieved ROSC. Changes in scattering coefficient (785 nm), [HbO2], StO2 and THC from baseline were significantly different in ROSC versus No-ROSC subjects (p < 0.01) after 10 min of CPR. Change in [HbO2] of + 1.3 µmol/L from 1-min of CPR achieved the highest weighted Youden index (0.96) for ROSC prediction. We demonstrate feasibility of quantitative, non-invasive FD-DOS neuromonitoring, and stable, specific, early ROSC prediction from the third minute of CPR.

scholarly journals Photonics of human saliva: potential optical methods for the screening of abnormal health conditions and infections

2021 ◽  
Author(s):  
Jijo Lukose ◽  
Sanoop Pavithran M. ◽  
Mithun N. ◽  
Ajaya Kumar Barik ◽  
Keerthilatha M. Pai ◽  
...  
Keyword(s):  
Biomedical Applications ◽  
Viral Infections ◽  
Clinical Specimen ◽  
Human Saliva ◽  
Medical Diagnostics ◽  
Optical Methods ◽  
Health Conditions ◽  
Personal Health ◽  
Fast Detection ◽  
Non Invasive

AbstractHuman saliva can be treated as a pool of biological markers able to reflect on the state of personal health. Recent years have witnessed an increase in the use of optical devices for the analysis of body fluids. Several groups have carried out studies investigating the potential of saliva as a non-invasive and reliable clinical specimen for use in medical diagnostics. This brief review aims to highlight the optical technologies, mainly surface plasmon resonance (SPR), Raman, and Fourier transform infrared (FTIR) spectroscopy, which are being used for the probing of saliva for diverse biomedical applications. Advances in bio photonics offer the promise of unambiguous, objective and fast detection of abnormal health conditions and viral infections (such as COVID-19) from the analysis of saliva.

93 Does Spinal Bone Mineral Density Predict An Absolute 10 Year Probability of Sustaining A Major Osteoporotic Fracture

2021 ◽  
Vol 50 (Supplement_1) ◽  
pp. i12-i42
Author(s):  
A Nandi ◽  
N Obiechina ◽  
A Timperley ◽  
F Al-Khalidi
Keyword(s):  
Bone Mineral Density ◽  
Bone Mineral ◽  
Osteoporotic Fracture ◽  
Negative Correlation ◽  
Pearson Correlation ◽  
Fragility Fractures ◽  
Mineral Density ◽  
Major Osteoporotic Fracture ◽  
T Score ◽  
The Mean

Abstract Introduction Spine and hip bone mineral density (BMD) have previously been shown to predict the risk of sustaining future fractures. Although these have been shown in population studies, there is a paucity of trials looking at the relationship between BMD and 10 year probability of major osteoporotic fractures (Using FRAX UK without BMD) in patients with previous fragility fractures. Aims To evaluate the correlation between spinal T-score and an absolute 10 year probability of sustaining a major osteoporotic fracture (using FRAX without BMD) in patients with prior fragility fractures. Methods A retrospective cross-sectional analysis of 202 patients (29 males and 173 females) with prior fragility fractures attending a fracture prevention clinic between January and August 2019 was performed. Patients with pathological and high impact traumatic fractures were excluded. The BMD at the spine was determined using the lowest T-score of the vertebrae from L1 to L4. Using the FRAX (UK) without BMD, the absolute 10 year probability of sustaining a major osteoporotic fracture was calculated for each patient. Statistical analysis was performed using SPSS 26 software. Results The mean T-score at the spine was −1.15 (SD +/− 1.90) for all patients, −0.68 (SD +/− 0.45) for males and − 1.23 (SD +/− 0.14) for females. The mean FRAX score without BMD for major osteoporotic fracture was 18.5% (SD +/− 8.84) for all patients, 11.41% (SD +/−0.62) and 19.7% (SD +/−0.68) for males and females respectively. Pearson correlation coefficient showed a statistically significant, slightly negative correlation between spinal T- score and the FRAX (UK) without BMD (r = −0.157; p &lt; 0.05). Correlation was not statistically significant when males (r = 0.109; p = 0.59) and females (r = 0.148; p = 0.053) were considered independently. Conclusion In patients with prior fragility fracture spinal BMD has a statistically significant negative correlation with an absolute 10 year probability of sustaining a major osteoporotic fracture.

Quantifying Internal Load in Pre-Professional Contemporary Dancers: The Association Between Objective Heart-Rate Derived Outcome Measures and Subjective Dancers’ and Teachers’ Perceptions

2021 ◽  
Author(s):  
Janine H. Stubbe ◽  
Benjamin Soerel ◽  
Raôul Oudejans ◽  
Jolan Kegelaers ◽  
Rogier M. van Rijn
Keyword(s):  
Heart Rate ◽  
Perceived Exertion ◽  
Pearson Correlation ◽  
Correlation Coefficients ◽  
First Year ◽  
Contemporary Dance ◽  
Teachers Perceptions ◽  
Non Invasive ◽  
Subjective Perceptions ◽  
Training Impulse

Background: Monitoring heart rate is one of the most common methods used to quantify internal training load (ITL) in athletes. The aim of this study was to determine whether subjective measurements can be used as a simple, non-invasive, and inexpensive method for assessing ITL in pre-professional contemporary dancers.Method: A total of 16 first-year contemporary dance students participated in this study. Students wore heart rate monitors during 56 training sessions. After each session, students completed the rate of perceived exertion (RPE) scale and teachers completed the rate of observed exertion (ROE) scale. For each session, we calculated the session-RPEs (sRPE), session-ROEs (sROE), and heart-rate-derived ITLs [i.e., Banister TRaining IMPulse method (TRIMP) and Edwards TRIMP]. Pearson correlation coefficients were calculated to determine the association between sRPE, sROE, Banister TRIMP, and Edwards TRIMP.Results: Between-individual correlation between Banister TRIMP and subjective dancers’ (sRPE) and teachers’ perceptions (sROE) were moderate (r = .49, p < 0.01) to large (r = .57, p < 0.01). Between-individual correlations between Edwards TRIMP and the subjective perceptions (sRPE and sROE) were very large (r = .74, p < 0.01; and r = .79, p < 0.01). There was a statistically significant large (r = 0.52, p < 0.01) to almost perfect (r = 0.93, p < 0.01) within-individual correlation between the sRPE and the two measured TRIMP methods. There was a statistically significant small (r = .29, p < 0.01) to almost perfect (r = .92, p < 0.01) within-individual correlation between the sROE and the two measured TRIMP methods. Conclusion: The results of this study suggest that the sRPE is a simple, non-invasive, inexpensive, and valid method for quantifying ITL in pre-professional dancers.

scholarly journals Negative Correlation between Placental Growth Factor and Endocan-1 in Women with Preeclampsia

2018 ◽  
Vol 40 (10) ◽  
pp. 593-598 ◽  
Author(s):  
Marta Hentschke ◽  
Edson da Cunha Filho ◽  
Matias Vieira ◽  
Letícia Paula ◽  
Hiten Mistry ◽  
...  
Keyword(s):  
Growth Factor ◽  
Negative Correlation ◽  
Pearson Correlation ◽  
Maternal Plasma ◽  
Placental Growth Factor ◽  
Analysis Of Covariance ◽  
Angiogenic Factor ◽  
Vascular Endothelial ◽  
Pearson Correlation Test ◽  
The Difference

Objective To analyze endocan-1, a biomarker of vascular endothelial related pathologies, and the placental growth factor (PlGF), an angiogenic factor and a placental dysfunction marker in patients with preeclampsia (PE). Methods Case-control study conducted at Hospital São Lucas, in the city of Porto Alegre, Brazil. Endocan-1 and PlGF levels were quantified in the maternal plasma using the MagPlexTH-C microsphere system (MAGPIX System, Luminex, Austin, Texas, US) and evaluated through analysis of covariance (ANCOVA) and adjusted by body mass index (BMI), gestational age and maternal age. To estimate the difference between the groups, the mean ratio (MR) and the 95% confidence interval (95%CI) were calculated. The Pearson correlation test was used to establish any association between endocan-1 and PlGF levels. The null hypothesis was rejected when p < 0.05. Results The group of patients was composed by normotensive (n = 67) patients and patients with PE (n = 50). A negative correlation between endocan-1 and the PlGF was noted in the entire normotensive group (linear correlation coefficient [r] = −0.605; p < 0.001), as well as in the PE group (r = −0.545; p < 0.001). Conclusion Endocan-1 levels are increased in patients with PE, and are inversely correlated with PlGF levels. We suggest that it is important to analyze angiogenic and proinflammatory molecules concomitantly in women with PE to better understand the pathophysiology of the disease. Both molecules are strong candidates for PE biomarkers, and future studies will examine any mechanisms connecting these factors in PE.

scholarly journals Will Musculoskeletal Conditions of Shoulder Affect the Hand Function and Hand-Eye Coordination? A Cross-Sectional Analysis

2020 ◽  
pp. 17-20
Author(s):  
Senthil Kumar B ◽  
Subbaiah S ◽  
Arunachalam Ramachandran ◽  
Mohammad Sidiq ◽  
Mahendra Yadav ◽  
...  
Keyword(s):  
Shoulder Pain ◽  
Negative Correlation ◽  
Hand Function ◽  
Negative Relationship ◽  
Rank Correlation ◽  
Cross Sectional ◽  
Shoulder Pathology ◽  
Hand Eye Coordination ◽  
Spearman Rank Correlation Analysis ◽  
Sectional Analysis

Objective: To analyze the Hand Function (HF) and Hand-Eye Coordination (HEC) among subjects with shoulder conditions resulting in pain and disability. Methodology: In these cross-sectional 47 subjects with selected shoulder pathology between 30 to 60 years participated. Shoulder pathology was measured in terms of pain and disability using the SPADI scale. These values were correlated with Purdue pegboard and Balloon tossing task and Wall Ball Bounce task. Results: Spearman rank correlation analysis of SPADI pain component revealed that there was a negative correlation with HF (R= -0.596, p<0.001), but there was significant correlation with HEC1 (R= -0.260, p= 0.078) and HEC2 (R= -0.217, p= -0.144). Though there was no correlation a negative relationship was observed between the variables. In the correlation of SPADI disability component there was a perfect negative correlation with HF (R= -0.870, p<0.001), with HEC1 (R= -0.588, p<0.001) and HEC2 (R= -0.541, p<0.001). Conclusion: This study concludes that shoulder pain negatively influences the Hand Function, whereas the shoulder disability negatively influences both Hand Function and Hand-Eye Coordination. The therapist should consider assessing and treating HF and HEC in patients with shoulder pain and disability in the future.

scholarly journals Association of Maternal Hemoglobin and Birth Weight at Paropakar Maternity and Women’s Hospital, Kathmandu

2017 ◽  
Vol 11 (2) ◽  
pp. 20-23
Author(s):  
Safiur Rahman Ansari ◽  
Gehanath Baral
Keyword(s):  
Birth Weight ◽  
Negative Correlation ◽  
Strong Correlation ◽  
Neonatal Death ◽  
Maternal Age ◽  
Pearson Correlation ◽  
Mode Of Delivery ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional

Aims: To examine the association between maternal hemoglobin with birth weight.Methods: Cross sectional study of obstetrics database at Paropakar Maternity and Women’s Hospital. Hospital delivery of over 18 years of age women tested for Pearson correlation using SPSS-17.Results: Total of 2085 cases analyzed. There was mean hemoglobin value of 12.05 ± 1.30 (95% CI=11.992-12.103) g/dL and no any significant impact on mode of delivery (p=0.15) and neonatal death (p=0.736). There was a small but a significant correlation (p<0.01) of maternal age with hemoglobin (r = 0.106) and birth weight (r = 0.093); but a very small negative correlation between maternal hemoglobin and birth weight.Conclusions: Optimal maternal hemoglobin during labor rules out any strong correlation with birth weight.

scholarly journals Osteocalcin and Abdominal Aortic Calcification in Hemodialysis Patients: An Observational Cross-Sectional Study

2021 ◽  
Vol 12 ◽  
Author(s):  
Fengyu Jia ◽  
Suxia Wang ◽  
Ying Jing ◽  
Hanhui Zhao ◽  
Peng Rong ◽  
...  
Keyword(s):  
Vascular Calcification ◽  
Negative Correlation ◽  
Pearson Correlation ◽  
Fibroblast Growth Factor 23 ◽  
Cross Sectional Study ◽  
Aortic Calcification ◽  
Maintenance Hemodialysis ◽  
Abdominal Aortic Calcification ◽  
Cross Sectional ◽  
Abdominal Aortic

ObjectivesTo investigate the serum level of osteocalcin (OC), also known as bone Gla protein, in maintenance hemodialysis (MHD) patients and its correlation with abdominal aortic calcification (AAC).MethodsFrom July 2017 to February 2020, we enrolled 108 adult MHD patients. Routine fasting blood laboratory tests were performed before the start of the second hemodialysis in a week. Abdominal aortic calcification score (AACs) was assessed within 1 month. Pearson correlation and Logistic regression were used to analyze the data.ResultsThe OC level was 231.56 (25.92,361.33) ng/ml, elevating significantly in this group of MHD patients. It had a positive correlation with serum phosphorus (r = 0.511, P = 0.001), intact parathyroid hormone(iPTH) (r = 0.594, P = 0.0001), fibroblast growth factor 23(FGF23) (r = 0.485, P = 0.003) and a negative correlation with age(r = -0.356, P = 0.039). Based on the AACs, patients were divided into two groups. Serum OC level were higher in patients with AACs≥5 (p=0.032). A multiple logistics regression analysis revealed that age (odds ratio [OR]1.14, P=0.005) and OC(OR=1.10, P=0.008)were risk factors for high AACs(≥5).ConclusionThe study implicated that OC elevated significantly in this group of MHD patients.OC is positively correlated with phosphorus, iPTH, FGF23, and a negative correlation with age. OC was a risk factor for vascular calcification in this study, but this study did not classify osteocalcin as c-OC and unOC. Whether unOC is associated more directly with vascular calcification requires further study.

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