scholarly journals MAGNESIUM SULPHATE VERSUS PHENYTOIN FOR ECLAMPSIA: ONE YEAR PROSPECTIVE STUDY

2003 ◽  
Vol 41 (141) ◽  
pp. 247-52
Author(s):  
Mona Sharma ◽  
R Koirala ◽  
U Sharma ◽  
P Singh ◽  
S Gupta

Aim: Eclampsia is one of the important preventable causes of maternal mortality.This study aims to review the clinical profile of eclamptic women and compare thematernal mortality, recurrence of convulsions, other morbidities including the neonataloutcome with Magnesium Sulphate versus Phenytoin used for its management.Material and Methods: Prospective study was carried out in all the eclamptic patientadmitted in Gynae ward from April 2000 - April 2001 (Baisak 2057 to Chaitra 2057).Results: There were total of 30 patients.Most of the them (53.3%) were of the 15-20years of age group and three fourth (73%) were primigravidas. More than half (56%)were unbooked and one fourth were nonimmunised and illiterate .Blood pressure hadnever been measured in 63% of the patient . In the Phenytoin Group 68.75% hadrecurrences of fits where as in the Magnesium Sulphate Group only 21.43 % hadreccurence. In the Magnesium Sulphate group, 50% delivered normally whereas 42.5%needed caesarean section in the Phenytoin group Only 6.2% delivered normally andin 37.5 % forceps had to be applied. There were 37.50% admission to NeonatalIntensive Unit (NICU) for various complications in Phenytoin group whereas therewere only 14.2% NICU admission in Magnesium Sulphate group. There were twocases of neonatal deaths out of 16 neonates in the Phenytoin group whereas only oneout of 14 cases in Magnesium Sulphate group. There was only one maternal death inthese thirty patients and it belonged to the Phenytoin group.Conclusion: As proved in many other studies this study also showed that MagnesiumSulphate was superior to Phenytoin in terms of recurrence of fits, maternal and neonataloutcome. In our country where many deaths still occur due to Eclampsia the valuablerole of magnesium Sulphate should not be ignored and health personnels should betrained for its frequently than it is practiced to-day.Key Words: Eclampsia, Preeclampsia, Magnesium Sulphate, Phenytion.

1970 ◽  
Vol 10 (2) ◽  
pp. 48-51
Author(s):  
Quazi Tarikul Islam ◽  
Md Azizul Haque ◽  
ASM Shawkat Ali ◽  
ARM Saifuddin Ekram ◽  
Sultana Monira Hussain ◽  
...  

1068 randomly sampled adult Bangladeshi people were studied during a period of six months from October 2004 to March 2005. It was a randomized, prospective study. Cases that fulfilled two criteria of metabolic syndrome (MetS) were evaluated to see pattern and types of MetS. Out of 1068 patients, 110 (10.3%) fulfilled the inclusion criteria. 101 (9.4%) cases were labeled as metabolic syndrome according to NCEP ATP III criteria, 09 cases had only two criteria. 40 cases were male & 70 cases were female (M:F= 1:1.8). Mean age of patients with was 44.88, ranging from the age of 20-68 years. Majority (55%) of the patients were in the age group of 30-49 years. Half of the cases had BMI 30-34.9. Mean body weight of male was 85.9 kg and of female was 78.2 kg. Mean waist circumference of male was 41.7 inches and of female 40 inches. Mean HDL for male was 38.3 mg/dL and for female is 40.2 mg/dL. Mean Triglyceride for male was 172.1 and for female was 169.3 mg/dL. Mean total cholesterol for male was 216.7 and for female was 207.6 mg/dL. Mean systolic blood pressure (SBP) for men is 162 mm Hg & diastolic blood pressure (DBP) 99 mm Hg and for female mean SBP 155 and DBP 96 mm Hg. Metabolic syndrome is more prevalent in the 3rd and 4th decade of life in both sexes. It is almost twice common in female than male. Combination of hypertension, obesity & dyslipidemia comprises nearly 40% of its presentation.    doi: 10.3329/jom.v10i2.2813 J MEDICINE 2009; 10 : 48-51


2018 ◽  
Vol 5 (2) ◽  
pp. 31-34
Author(s):  
Shreedhar Acharya ◽  
Bhaktabatsal Raut

AIM: This study was done to find out the incidence and to analyse the various indications for caesarean sections at Lumbini Zonal Hospital.MATERIALS & METHODS: This was a hospital based retrospective study done at Lumbini Zonal Hospital, Butwal. The case files of all the women who had caesarean delivery over the period of one year from 2071/4/1 to 2072/3/32 were reviewed. Various indications of caesarean sections were analysed for the incidence, age, parity, elective vs emergency caesareans.RESULTS: Out of 7589 deliveries, 1316 (17.34%) had caesarean section. Most common indications were previous caesarean 275 (20.89%), non progress of labour 245 (18.61%), cephalopelvic disproportion 222 (16.86%), fetal distress 215 (16.33%), etc. Majority of caesarean 1226 (93.16%) was done in the age group of 20-30yrs, primipara 702 (53.34%), and elective caesarean sections 766 (58.2%).CONCLUSION: Caesarean section rate at Lumbini Zonal Hospital was optimal. Most common indication was repeat caesarean. The overall reduction in caesarean section rate can be met through reduction of elective caesarean with the promotion of trial of labour.Study also concludes that there is a relation between working duration and health problems, and the problems increase as the duration at work increases.Journal of Universal College of Medical Sciences, Vol. 5, No, 2, 2017, Page: 31-34


Author(s):  
Sana B. Mustafa ◽  
Abdulhadi M. Elbashir ◽  
Adil Y. Waddad ◽  
Abdelrahman M. A. Ibrahim

Background: Placenta praevia is a source of drastic pregnancy, fetal and neonatal complications. There was variable incidence in the literature in different parts of the world and within the same country regions. We carried out this study to find the impact in our area and the possible risk factors for this serious obstetric problem.Methods: This study is a cross-sectional descriptive, one-year retrospective one-year prospective study, carried out from April 2014 to April 2016. All pregnant women attended the antenatal care clinic in Najran University Hospital during the study period, were included.Results: The incidence of placenta praevia was found to be 2.7%. AMONG the study group, the most affected age group was between 20-29 years. Previous placenta praevia and previous caesarean  section were the significant risk factors P=0.00 and 0,017 repectively.Conclusions: The incidence of placenta praevia in Najran KSA in this study was high, compared to other regions in Saudi Arabia and the majority of the international figures. Caesarean section and previous placenta praevia were the significant risk factors for placenta praevia in this study.


Author(s):  
Deepti Kiran Nene ◽  
Tushar Chandrakant Baheti ◽  
Vidyadhar B. Bangal

Background: Caesarean section is one of the commonly performed operation in women due to safety reason and modern techniques. Primary caesarean section in the multipara means first caesarean section done in the patients who had previously delivered vaginally once or more. Aims and objectives of this study were to know association of various parameters like Age, Parity, Haemoglobin, Blood Pressure, Baby weight, Perinatal and Maternal Mortality with primary caesarean section among multipara.Methods: This was a prospective study of primary caesarean section in multipara women admitted at tertiary care hospital in western rural Maharashtra during the period of 6 months from January 2018 to June 2018. Multipara with pregnancy of >28 weeks gestation (gravida 2 and above), each of whom has had a previous vaginal delivery of >20 weeks gestation were included. Women with previous abortions and previous section were excluded.Results: Total 1705 sections were performed during the same period out of total 4648 deliveries. Out of these sections 194 sections were performed in multipara for the first time. Maximum numbers of patients (58%) were in the age group of 15-24 years and Parity 2 (68%). Almost 70% women among multipara have Hb <11 Mgm/dl. Most of the patients (84.53%) have normal Blood pressure readings. Most of the babies’ i.e.70 (36.08%) have birth weight in the range of 2.5-3 kg. Out of 194 deliveries, there were only 3 neonatal deaths (1.54%) and 1 maternal death (0.51%).Conclusions: Proper antenatal and intrapartum care and early referral can reduce the maternal and perinatal morbidity and mortality in multipara. 


2020 ◽  
pp. 1-3
Author(s):  
Prabhat Kumar Sinha ◽  
Kumari Suruchi ◽  
Pradeep Kumar Sharma ◽  
Debarshi Jana

To Study failure of thrombolysis with streptokinase in acute myocardial infarction using E.C.G criteria a prospective study of patients presenting with acute myocardial infarction in Department of Medicine, Darbhanga Medical College and Hospital, Laheriasarai, Bihar for a period of one year from December 2018 to November 2019. A total of 220 patients who presented with acute myocardial infarction were included in the study. Out of 220 patients 193(87.7%) males and 27 (12.3%) females participated in the study. All the patients underwent thrombolysis with streptokinase. Out of 220 patients who were being thrombolysed with streptokinase, most of them (97; 41.1%) were in the age group of 56-65 years. Out of all the patients who underwent thrombolysis (n=220), thrombolytic failure was observed in 121 (55%) patients. Failure rate was significantly higher in the age group of 56-65 years (88; 72.7%). Significantly higher prevalence of thrombolytic failure with streptokinase was observed among diabetic patients (65.2% ) as compared to non diabetics (52.3%).


Author(s):  
D. M. Christe ◽  
Shaanthy T. K. Gunasingh ◽  
V. Bharani

Background: To find out the maternal and neonatal outcome and background characteristics of women delivering by repeat caesarean section in a tertiary care centre in Chennai, South India.Methods: Parturition records for the year 2017, were accessed and case records, for the calculated sample size were selected. Demographic features, obstetric history, gestational age and antenatal complications were recorded. Maternal outcome and baby details including sex of the baby, birth weight, APGAR and admission to New born Intensive Care Unit (NICU) data and acceptance of postpartum contraception was noted.Results: In the study group, 156 women delivered by repeat caesarean section.  The age group of women ranged from 20 years to 38 years.  Majority of 83.4% of women were Para one.  Threatening rupture was recorded in 2.6% of women. The risk of previous two CS scars was noted in 3.2% of women. More than 41% of women had other complications. Most often observed complications were Gestational hypertension, Gestational diabetes, preeclampsia and eclampsia. Pregnancy complications of oligohydramnios, twins, breech and abnormal presentation, were significant. 1% of women had associated medical complications of anaemia and hypothyroidism.  Maternal and Fetal causes were the most important indication for caesarean section in 74% of women. There were no maternal deaths in present study group. Postpartum contraception was accepted by 55 % of women.Conclusions: Majority of repeat caesarean section was observed most commonly in para one women in the age group of 26-30 years More than 41% of women had associated medical and obstetric complications. There were no maternal deaths in this study. Neonatal deaths were 2.5%.


2021 ◽  
Vol 8 (32) ◽  
pp. 2956-2961
Author(s):  
Gandikota Venkata Prakash ◽  
Ajay Babu K ◽  
Madan Sundar ◽  
Purushotham G ◽  
Saddi Tejaswi ◽  
...  

BACKGROUND Cholecystectomy is a common surgical procedure done worldwide for both benign and neoplastic conditions. Cholecystectomy for benign conditions is performed based on clinical signs, symptoms, Ultrasound, CT. Hence there is fair chance of missing early malignant lesions like carcinoma-in-situ and other early carcinomas. Aim: The aim of the study is to analyse histopathological variations in post cholecystectomy specimens done for benign lesions. METHODS The study was conducted in Department of General Surgery, SVRRGGH, Tirupati, for a period of one year, from March 2019 to April 2020. This is a prospective Study conducted among 100 Patients, conducted over a period of one year from time of IEC approval from March 2019 to April 2020. All patients who underwent cholecystectomy for benign biliary disease and gall stone were included in the study. All patients with pre-diagnosed empyema gallbladder, gallbladder malignancy, gallbladder mass, and gallstones associated with obstructive jaundice are excluded from the study. RESULTS In our study, 100 cases of gall bladder disease were studied in the age group of 18 – 70 years, for a period of 1 year from March 2019 in the department of General surgery, SVRRGGH. Occurrence is high in patients of age group 18 – 45 years (65 %). The male to female ratio is 0.5:1 with female preponderance. The most common histopathologic finding was chronic calculus cholecystitis (59 %).Adenocarcinoma of gall bladder (2 %) of the cases with no preoperative suspicion of malignancy. CONCLUSIONS The occurrence of Incidental GBC found in my study is 2 %. Due to high estimate of residual disease, re-resection is still a curative option and is to be considered for pT2 & pT3, but not CBD removal. Prognosis usually is dismal, and five-year survival rates have been reported to be less than 5 % for more advanced stages. KEYWORDS Histopathology, Variations, Cholecystectomy, Specimen, Benign


Author(s):  
Amarpali K. Shivanna ◽  
Spandana S. ◽  
Rajani Vaidya

Background: VBAC has reduced the rate of repeat caesarean section in modern medicine. VBAC-TOL is successful in 60-80% of acceptable candidates if applied to all patients presenting with prior caesarean procedure (8.2-8.5%), there is potential to increase the overall vaginal delivery rate by 5%. Though the safety of VBAC in carefully selected patients have been demonstrated in several studies, controversy continues over when to advise patients who had caesarean section to undergo TOL. The purpose of current study was to know the success of VBAC, to know the maternal morbidity and mortality and foetal outcome in VBAC group.Methods: It was a prospective study performed on women with one previous LSCS admitted to tertiary care hospital for a period of one year from August 2018 to August 2019 at DM Waynad institute of medical sciences, Waynad.Results: In the present study 292 women with one previous LSCS were selected, among them 32 women had elective LSCS for various indications, 260 women underwent TOL. Among 260 women, 152 women achieved VBAC (58.46%) and 108 women underwent LSCS following failed TOL. Maternal morbidity was 9.61%. The incidence of scar dehiscence was 2.69% and uterine rupture was 0.38%. There was no maternal and foetal mortality in this study. NICU admission was 4.6%.Conclusions: Trial of labour should be encouraged in women with one previous LSCS with no obstetric complications.


QJM ◽  
2020 ◽  
Vol 113 (Supplement_1) ◽  
Author(s):  
R H Elkabarity ◽  
R M M Ali ◽  
J N Naseef ◽  
M M F Hanna

Abstract Background pre-eclampsia is defined as a disorder that occurs in pregnancy after twenty weeks of gestation which manifests as hypertension and proteinuria with at least one maternal organ dysfunction involvement with an incidence of 5-10% of all pregnancies. Aim of the Work our study will examine the hemodynamic effects of adding two different doses of magnesium sulphate to bupivacaine in patients with severe preeclampsia undergoing caesarean section using spinal anesthesia. Patients and Methods: type of Study Prospective comparative study; it was done after approval of the Research Ethics Committee of Anesthesia, Intensive Care and Pain Management Department, Ain Shams University. Study Setting Ain Shams University Hospitals, Cairo, Egypt. Study Period 3 months. Study Population Pregnant females with severe preeclampsia undergoing caesarian section. Results results of this study indicated that the addition of magnesium sulfate at a dose of 100mg compared to the dose of 50 mg to bupivacaine showed that increasing the dose of magnesium sulfate had no significant hemodynamic effect (systolic blood pressure, diastolic blood pressure and heart rate) on severe preeclamptic patients undergoing caesarean section. But the addition of 100 mg magnesium sulfate lead to a significant delay in the onset of both sensory and motor blockade, and prolonged the duration of sensory and motor blockade compared to the addition of 50mg magnesium sulphate. Also there is no significant difference between the addition of 50 &100mg on shivering, nausea and vomiting, sedation, postoperative pain score (at 2,4 and 8 hours) and APGAR score (at 1 and 5 min). Conclusion the addition of magnesium sulfate at a dose of 100mg compared to the dose of 50 mg to bupivacaine in our study, showed that increasing the dose of magnesium sulfate had no significant hemodynamic effect (systolic blood pressure, diastolic blood pressure and heart rate) on severe preeclamptic patients undergoing caesarean section.


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