scholarly journals TO STUDY THE PATTERN OF DYSLIPIDEMIA IN HYPOTHYROID PATIENTS

Author(s):  
Mohammed Tarik ◽  
Subhash Chandra

Background: Thyroid hormones play an important role in regulating lipid metabolism and thyroid dysfunctions can result in lipid abnormalities which increase the risk of endothelial dysfunction, hypertension and cardiovascular disease. Methods: A cross-sectional study was conducted on 100 patients selected as a sample of convenience in this cross sectional study from out-patient department of Medicine. Meticulous history taking and thorough clinical examinations were done. Report of lipid profile and thyroid function tests were recorded from patients file. All the information's were recorded in a pre-desigaed structured questionnaire. Collected data were classified, edited, coded and entered into the computer for statistical analysis by using Epi-info software. Results: The serum TC, TG and LDL levels in hypothyroid individuals were significantly higher than euthyroid subjects. Conclusion: We conclude that hypothyroid subjects had dyslipidemia. The present study indicated that hypothyroidism was associated with an abnormal lipid profile, especially with respect to the levels of TC, LDL and TG. Keywords: Total cholesterol, Triglycerides and LDL

2016 ◽  
Vol 6 (2) ◽  
pp. 156
Author(s):  
K. G. Kibria ◽  
M. R. Alam ◽  
H. K. Paul ◽  
M. Fariduddin ◽  
M. A. Hasanat

<p><strong>Background:</strong> An association between thyroid dysfunction and dyslipidemia prevails. Levels of total cholesterol, low density lipoprotein cholesterol, triglycerides tend to increase as thyroid function declines.</p><p><strong>Objective:</strong> To find out the pattern of dyslipidemia in hypothyroid patients. <strong></strong></p><p><strong>Methods:</strong> Sixty cases were selected as a sample of convenience in this cross sectional study from in-patienl depa1tment of Medicine and Endocrinology, BSMMU. Meticulous history taking and thorough clinical examinations were done. Report of lipid profile and thyroid function tests were recorded from patients file. All the information's were recorded in a pre-designed sttuctured questionnaire. Collected data were classi­fied, edited, coded and entered into the computer for statistical analysis by using SPSS. <strong></strong></p><p><strong>Results:</strong> Among the 60 cases, 43 (72%) were female; 17(28%) were male. Age range was 24-59 years with a mean age of 38.80 (± I 0.35) years. Majority 38(65%) were housewife, followed by service holder 11(18.33%), 08(13.3%) were business men and 02(3.3%) had other occupations. Majority 42(70%) patients were taking thyroxin. Mean Total cholesterol (TC), LDL cholesterol, Triglycer­ide (TG) and HDL were 222.20(±42.25); 138.63(±31.51); 243.36(±83.13) and 37.30(±5.12) respectably. <strong></strong></p><p><strong>Conclusion:</strong> All hypothyroid subjects had dyslipidemia. The present study indicated that hypothyroidism was associated with an abnormal lipid profile, especially with respect to the levels of total cholesterol and triglyceride.</p>


2021 ◽  
pp. 99-111
Author(s):  
Edith N. Genéz Yeza ◽  
Claudia N. Mir ◽  
Rocío M. Ares ◽  
Williams R. Pedrozo ◽  
Graciela A. Bonneau

Thyroid dysfunctions are a cause of morbidity and disability worldwide. Little information has been found on the prevalence of thyroid dysfunctions in Paraguay, so this study provides data on their presentation. The objective was to determine the prevalence of thyroid dysfunction and its relationship with the lipid profile in adult outpatients attending the laboratory of the Regional Hospital of Encarnación, during January-November 2016. A descriptive cross-sectional study was performed, based on the review of 250 medical records, 84 % of whom were women; the median age was 39 (35-47) years in men and 36 (32-43) years in women. Thirty percent were hypothyroid and 3 % hyperthyroid; the most frequent thyroid dysfunction was subclinical hypothyroidism with 19 %. Highly significant differences were found for total cholesterol, LDL, VLDL and thyrotrophin between hypothyroid vs euthyroid, with the former having more atherogenic profiles. Logistic regression was used to assess the contribution of dyslipidaemia, finding a significant association with hypothyroidism (OR=3.24(1.81-5.81), p<0.001). Thirty-three percent of this population sample, 1 in 3 individuals, had thyroid dysfunction. These could be managed appropriately and further complications could be avoided.


2019 ◽  
Vol 9 (4) ◽  
pp. 6-10
Author(s):  
Kushal Bhattarai ◽  
Nilu Manandhar

Background: Hyperuricemia, a pathologic consequence of over-production or under-excretion of uric acid, is a common biochemical picture in thyroid dysfunctions. This study was designed to determine the serum uric acid levels and the prevalence rates of hyperuricemia in thyroid dysfunctions. Methods: A cross-sectional study was conducted at College of Medical Sciences and Teaching Hospital, Chitwan in which Serum uric acid concentrations of male and female participants, 30 years or older with the diagnosis of hypothyroidism or hyperthyroidism were estimated. Hyperuricemia was defined as uric acid levels >6.8mg/dL (males) and >6.0 mg/dL (females). Descriptive statistics using frequency with percentage and inferential statistics using parametric and non-parametric tests were used. Results: In the total 249 participants, the prevalence of hyperuricemia was 30.5% (32.9% in hyperthyroid and 26.1% in hypothyroid patients). Similarly, the mean serum uric acid levels in these patients was 5.46 ± 1.88mg/dL (5.60 ± 1.71 in hyperthyroid and 5.20 ± 2.13mg/dL in hypothyroid patients). Hyperuricemia was present in 32.6% of the female and 27.6% of the male patients. Likewise, the rate was 28.1% in 30–40 years old, 30.0% in 40–50 years old, 30.9% in 50–60 years old, and 32.8% in >=60 years old participants. There was no significant association between hyperuricemia and age or gender in overall participants and in participants of either of the two groups of thyroid dysfunctions (p>0.05). Conclusions: The reported prevalence of hyperuricemia in thyroid dysfunctions justifies the need of further studies to understand the causal relationship between thyroid status and serum uric acid.


2013 ◽  
Vol 25 (1) ◽  
pp. 21-24 ◽  
Author(s):  
MAH Khan ◽  
Ishaque Majumder ◽  
M Hoque ◽  
M Fariduddin ◽  
FH Mollah ◽  
...  

Hypothyroidism is an important metabolic disorder and is associated with many biochemical abnormalities. Many studies were done regarding the biochemical status of hypothyroid patients including lipid profile. But controversies still prevail. So, a cross sectional study was done in our population to evaluate lipid profile status of hypothyroid patients compared to age and sex matched healthy euthyroid persons. In our study mean serum total cholesterol, LDL cholesterol and triacylglycerol levels in cases and controls were 241.56 ± 60.05 vs 146.94 ± 23.21 mg/dL, 151.96 ± 59.60 vs 71.43 ± 26.83 mg/dL and 212 ± 100.73 vs 98.87 ± 39.69 mg/dL respectively with p values < 0.001 whereas HDL cholesterol was found significantly decreased in cases compared to controls (49.59 ± 11.69 vs 55.89 ± 11.70 mg/dL with p value < 0.05). Results of our study suggest that dyslipidemias are associated with hypothyroidism. Therefore, patients presenting with dyslipidemia are recommended for investigation to explore hypothyroidism DOI: http://dx.doi.org/10.3329/medtoday.v25i1.15904 Medicine Today 2013 Vol.25(1): 21-24


2020 ◽  
Vol 11 (SPL1) ◽  
pp. 1144-1150
Author(s):  
Muralidharan V A ◽  
Gheena S

Covid -19 is an infectious disease caused by the newly discovered strain of coronavirus. As there is no vaccine discovered, the only way to prevent the spread is through following the practice of social isolation. But prolonged isolation may also lead to psychological stress and problems. The objective of the survey was to assess the knowledge and awareness of preventive measures against Covid 19 amongst small shop owners. A web-based cross-sectional study was conducted amongst the small shop owners.  A structured questionnaire comprising 15-17 questions had been put forth to assess the Covid 19 related knowledge and perception. The shopkeepers were contacted telephonically and responses recorded. The data analysis was performed using IBM SPSS statistics. Although the majority of the population had a positive perception about the preventive measures against the Covid spread, 36% of the shopkeepers were not aware of the preventive measures against the Covid spread. This study found optimal knowledge and perception of the preventive measures against Covid spread among the shopkeepers but misinformation and misunderstanding still prevailing. The shopkeepers are crucial in the prevention of the spread of Covid 19 and educating them might aid us in the fight against Covid- 19. 


2019 ◽  
Author(s):  
Chanda Chalela

BACKGROUND ABSTRACT Introduction a study on prevalence of ITN use was carried out in Buchi community Kitwe Zambia from August to October 2019 OBJECTIVE Prevalence of ITN in BUchi METHODS Methodology: This was a cross sectional study design. A structured questionnaire was used to ascertain ownership and utilization and oral interviews, 200 households were targeted 844 individual covered across the 200 households. Data was analyzed with SPSS version 23. RESULTS ABSTRACT Introduction a study on prevalence of ITN use was carried out in Buchi community Kitwe Zambia from August to October 2019 Methodology: This was a cross sectional study design. A structured questionnaire was used to ascertain ownership and utilization and oral interviews, 200 households were targeted 844 individual covered across the 200 households. Data was analyzed with SPSS version 23. Findings: household ownership of at least an ITN was 52% and individual utilization at 37.6%, with 0.825 ITN/households and 0.195ITN /individual. Malaria prevalence of 52.4% /household and a 12.4% of the population. With 47.6% malaria patient coming from households with ITN and 60% of households with ITN have insufficient coverage.61% of malaria patient were female and 31 % male. however there was no significant relation between Gender and malaria prevalence in study area (p value was >0.05). Malaria cases distribution with age groups, 0-15yrs old represented 49.5%, 16-30 yrs., was at 27.6% and the over 30 yrs. case were at 22.9% .use of other preventive measures 23% used mosquito repellent ,others methods 1% with those not using any other methods 76%. CONCLUSIONS Conclusion The study showed clearly that malaria still poses a problem .the prevalence rate of malaria was still high 12.4% of the population and 52.4% of households. With high prevalence of malaria of 49.5% for 0-15yrs.the difference between ownership 52% and Utilization 37.6% showed that even household with ITN, the ITN were not sufficient.60% of households with ITN, the ITN were not sufficient for all occupants


Author(s):  
Sambedana Mohanty ◽  
Manasee Panda

AbstractBackgroundAdolescent girls are vulnerable to many problems, undernutrition being the most common. This results in growth restriction resulting in stunting, wasting, underweight and last but not the least iron-deficiency anaemia. Nutritional needs are high during puberty which later leads to complications during pregnancy and its outcomes.Materials and methodsA field based cross-sectional study was carried out to assess the nutritional status of the girls and to determine the various factors responsible for undernutrition. After clearance from the Institution Ethical Committee (IEC) and permission from Child Development Programme Officer (CDPO), the study was conducted in the anganwadi centres (AWC) of urban slums in the field practice area of the Department of Community Medicine from the 1st October 2014 to the 31st October 2016. All the adolescent girls enlisted in the seven anganwadi centres were included as study subjects with their consent. A pre-designed, pre-tested and semi-structured questionnaire was used to collect data on following sections. (a) socio-demographic profile and (b) nutritional status. Dietary intake was taken using the 24-h recall method. Anthropometry was measured and haemoglobin (Hb) was estimated. SPSS version 21 was used for descriptive and analytic statistics.ResultsAmong the 160 girls 98(61.3%), 69(43.1%), 53(33.1%) were underweight, stunted and wasted, respectively. Anaemia was present among 144(90%) of the girls.ConclusionStrict monitoring of weekly iron and folic acid supplementation (WIFS) as well as nutrition education are essential measures to solve the problem of undernutrition among adolescent girls.


2021 ◽  
pp. 030157422110221
Author(s):  
Jyoti Mishra ◽  
Sudhir Kapoor ◽  
Jitendra Bhagchandani ◽  
Sonahita Agarwal ◽  
Vaibhav Vashishta ◽  
...  

Aim and Objective: To assess the level of awareness among local adult population (orthodontically untreated) regarding orthodontic treatment and procedures. Materials and Methods: A cross-sectional study was planned by accessing 100 subjects comprising of 2 groups (50 male and 50 female). After due ethical clearance, a self-structured questionnaire consisting of 17 questions was given to a group of randomly selected 100 individuals with an age range of 20 to 30 years. Results: The overall awareness of orthodontics as a speciality among both the groups was only 52% to 56%. Statistically insignificant difference was found in the knowledge and awareness of orthodontic treatment among both male and female subjects, that is, Group I and II. Also, those who knew about the orthodontic treatment did not opt for it because of high cost and longer duration involved. Conclusion: More than half of the population is unaware of the scope of orthodontic treatment, and thus, they do not seek any assistance. Hence, more efforts are needed to create awareness about orthodontics and the associated benefits.


Author(s):  
Zélia Pereira ◽  
Luís Cardoso ◽  
Ana Cláudia Coelho

Abstract Objectives: The aim of this study was to assess the knowledge and practices related to disaster preparedness among pet owners in North Portugal. The present research provides an evaluation of differences among pet owners regarding preparedness in the event of disasters. Methods: A cross-sectional study was conducted among a convenience sample of 155 pet owners between September and November 2018. Subjects were interviewed using a structured questionnaire with items addressing sociodemographic characteristics and questions related to owners’ emergency preparedness and practices. Results: In this study, 53.5% of the respondents thought about the possibility of a disaster. Only 21.3% of respondents reported having knowledge on the existence of a disaster kit for pets in case of an emergency. The majority (94.8%) of respondents said they were not aware of the preparedness county-level organization plans. Knowledge and preparedness were found to be significantly higher among dog owners compared with owners of other pet species. Conclusions: The results suggest that Portuguese pet owners have inadequate knowledge on how to prepare for inclusion of their pets in a disaster.


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