scholarly journals Pola Kepekaan Bakteri terhadap Antibiotik di Ruang Rawat Intensif RSPI Prof. Dr. Sulianti Saroso Jakarta

2017 ◽  
Vol 1 (2) ◽  
pp. 23
Author(s):  
Putriana Indah Lestari ◽  
Ika Susanti ◽  
Huda Rahmawati
Keyword(s):  
Escherichia Coli ◽  
Pseudomonas Aeruginosa ◽  
Klebsiella Pneumoniae ◽  
Acinetobacter Baumannii ◽  
Antibiotic Sensitivity ◽  
Secondary Data ◽  
Sensitivity Pattern ◽  
Important Health ◽  
Antibiotic Sensitivity Test ◽  
Antibiotics Sensitivity

Abstrak : Penyakit infeksi merupakan salah satu masalah kesehatan yang penting. Penggunaan antibiotik yang tidak rasional dan tepat guna pada pasien penyakit infeksi beresiko menyebabkan terjadinya resistensi. Tujuan dari penelitian ini yaitu untuk mengetahui pola kepekaan bakteri terhadap antibiotik pada pasien Ruang Rawat Intensif (ICU) RSPI Prof. Dr. Sulianti Saroso (RSPI-SS) Jakarta. Penelitian dilakukan deskriptif dan retrospektif terhadap data sekunder hasil uji kepekaan antibiotik dan jenis bakteri dari 107 pasien dalam kurun waktu 2011. Hasil menunjukkan 68 (65,4%) pasien mendapatkan hasil kultur positif dan uji kepekaan bakteri terhadap antibiotik. Jenis bakteri patogen yang dominan yaitu Acinetobacter baumannii (29,4%), disusul oleh Pseudomonas aeruginosa (27,9%), Klebsiella pneumoniae (13,2%) dan Escherichia coli (8,8%). Sebagian besar bakteri pada pasien ICU RSPISS telah berkurang kepekaannya (resisten) terhadap beberapa antibiotik. A. baumannii dan P. aeruginosa merupakan bakteri yang paling resisten terhadap antibiotik uji. Pola kepekaannya menunjukkan bahwa bakteri patogen mempunyai resistensi tertinggi terhadap erythromycin dan terendah terhadap amikasin.Infectious diseases is an important health problem. Irrational antibiotics usage is a leading cause in initiating drugs resistances. A preliminary study was conducted on the sensitivity pattern of microorganisms against antibiotics at the intensive care unit of Sulianti Infectious Diseases Hospital Jakarta. Retrospective. Secondary data were collected on the results of antibiotics sensitivity tests and species of microorganisms of 107 patients during the year 2011. Sixty eight (65,4%) patients were positive on microorganism culture test and tested on antibiotic sensitivity test. Predominance pathogenic species found were Acinetobacter baumannii (29,4%), followed by Pseudomonas aeruginosa (27,9%), Klebsiella pneumoniae (13,2%) and Escherichia coli (8,8%). Most species were less sensitive (resistant) to several antibiotics. The pattern of sensitivity showed that pathogenic microorganisms were the most resistant against erythromycin and the most sensitive antibiotics was amikacin.

scholarly journals Pola Kepekaan Bakteri Penyebab Pneumonia terhadap Antibiotika di Laboratorium Mikrobiologi RSUP Dr. M. Djamil Padang Periode Januari sampai Desember 2011

2015 ◽  
Vol 4 (2) ◽  
Author(s):  
Jaka Kurniawan ◽  
Erly Erly ◽  
Rima Semiarty
Keyword(s):  
Escherichia Coli ◽  
Staphylococcus Aureus ◽  
Research Method ◽  
Antibiotic Sensitivity ◽  
Secondary Data ◽  
Empiric Therapy ◽  
Test Results ◽  
Microbiology Laboratory ◽  
Sensitivity Pattern ◽  
Antibiotic Sensitivity Test

AbstrakPeningkatan resistensi bakteri penyebab pneumonia terhadap beberapa antibiotika yang lazim digunakan oleh klinisi dalam pemberian terapi empirik akan menyebabkan berkurangnya keefektifan terhadap terapi pneumonia. Hal ini akan berdampak semakin tingginya morbiditas dan mortalitas yang disebabkan oleh infeksi pneumonia. Tujuan penelitian ini adalah untuk mengetahui pola kepekaan bakteri penyebab pneumonia terhadap antibiotika di Laboratorium Mikrobiologi RSUP. Dr. M. Djamil Padang periode Januari 2011 - Desember 2011. Metode penelitian yang digunakan adalah deskriptif retrospektif terhadap data sekunder hasil uji kepekaan antibiotika dan jenis kuman dari 432 pasien, menunjukkan jenis bakteri penyebab pneumonia adalah Klebsiella sp, Streptococcus α haemolyticus, Staphylococcus aureus, Pseudomonas aeuruginosa, proteus sp, Basillus, Escherichia coli dan Enterobacter. Pola kepekaannya menunjukkan bahwa rata-rata semua bakteri tersebut mempunyai sensitivitas tertinggi terhadap Netilmicin, Meropenem, dan Sulbactam + Cefoperazone. Resistensi tertinggi ditunjukkan oleh Erithromycin, Ampicillin, Sulfamethroxazole + Trimethroprime,Tetracyclin, dan Choramphenicol.Kata kunci: antibiotika, bakteri penyebab pneumonia, pola kepekaan AbstractIncreased resistance of bacteria that cause pneumonia to some antibiotics that are commonly used by clinicians in the provision of empiric therapy, it will cause a reduction in the effectiveness of the treatment of pneumonia. This will lead to increasing morbidity and mortality caused by pneumonia infection. The objective of this study wass to determine the sensitivity pattern of bacteria that cause pneumonia to antibiotics in the Department of Microbiology Laboratory. Dr. M. Djamil Hospital Padang period from January 2011 to December 2011. The research method used was a descriptive and retrospective review of secondary data and antibiotic sensitivity test results of 432 patients types of germs. The results indicated the type of bacteria that cause pneumonia are Klebsiella sp, Streptococcus α haemolyticus, Staphylococcus aureus, Pseudomonas aeuruginosa, Proteus sp, Basillus, Escherichia coli, and Enterobacter. Sensitivity pattern showed that the average of all the bacteria has the highest sensitivity to Netilmicin, Meropenem, and Sulbactam + Cefoperazone, Highest resistance shown by Erithromycin, Ampicillin, Sulfamethroxazole Trimethroprime +, Tetracycline, and Choramphenicol.Keywords: antibiotics, the bacteria that caused pneumonia, sensitivity pattern

scholarly journals СИНТЕЗ ТА ДОСЛІДЖЕННЯ АНТИМІКРОБНОЇ АКТИВНОСТІ ДЕЯКИХ ПІРАЗОЛЗАМІЩЕНИХ 7H-[1,2,4]ТРИАЗОЛО[3,4-B][1,3,4]ТІАДІАЗИНІВ

2021 ◽  
pp. 5-13
Author(s):  
I. I. Myrko ◽  
T. I. Chaban ◽  
V. V. Ogurtsov ◽  
V. S. Matiychuk
Keyword(s):  
Escherichia Coli ◽  
Staphylococcus Aureus ◽  
Pseudomonas Aeruginosa ◽  
Candida Albicans ◽  
Drug Discovery ◽  
Klebsiella Pneumoniae ◽  
Acinetobacter Baumannii ◽  
Cryptococcus Neoformans ◽  
Antimicrobial Drug

Мета роботи. Здійснити синтез деяких нових піразолзаміщених 7H-[1,2,4]триазоло[3,4-b][1,3,4]тіадіазинів та провести дослідження антимікробних властивостей синтезованих сполук. Матеріали і методи. Органічний синтез, ЯМР-спектроскопія, елементний аналіз, фармакологічний скринінг. Результати й обговорення. У результаті взаємодії eтил (2Z)-хлоро(фенілгідразоно)ацетатів з ацетилацетоном було отримано етил 4-ацетил-5-метил-1-феніл-1H-піразол-3-карбоксилати. Зазначені сполуки піддали бромуванню, що дозволило одержати цільові бромкетони. Синтезовані на даній стадії етил 1-арил-4-(бромацетил)-5-метил-1Н-піразол-3-карбоксилати було введено у взаємодію з 4-аміно-5-арил(гетарил)-2,4-дигідро-3Н-1,2,4-триазол-3-тіонами з подальшим формуванням 1,3,4-тіадіазольного циклу та отриманням відповідних етил 1-арил-4-{3-арил(гетарил)-7H-[1,2,4]триазоло[3,4-b][1,3,4]тіадіазин-6-іл)}-5-метил-1H-піразол-3-карбоксилатів. Структура синтезованих сполук підтверджена даними елементного аналізу та ЯМР спектроскопією. В рамках міжнародного проекту "The Community for Antimicrobial Drug Discovery" (CO-ADD) за підтримки Wellcome Trust (Великобританія) і університету Квінсленда (Австралія) для синтезованих сполук здійснено скринінг антимікробної активності. Як тестові мікроорганізми використовували п'ять штамів бактерій: Escherichia coli ATCC 25922, Klebsiella pneumoniae ATCC 700603, Acinetobacter baumannii ATCC 19606, Pseudomonas aeruginosa ATCC 27853, Staphylococcus aureus ATCC 43300 та двох штамів грибків: Candida albicans ATCC 90028 і Cryptococcus neoformans ATCC 208821. Встановлено, що досліджувані сполуки виявляють різноманітну дію, від практично повної її відсутності до виразного антимікробного ефекту. Висновки. Здійснено синтез 12 нових етил 1-арил-4-{3-арил(гетарил)-7H-[1,2,4]триазоло[3,4-b][1,3,4]тіадіазин-6-іл)}-5-метил-1H-піразол-3-карбоксилатів. Зазначені речовини отримані шляхом взаємодії відповідних етил 1-арил-4-(бромацетил)-5-метил-1Н-піразол-3-карбоксилатів з 4-аміно-5-арил(гетарил)-2,4-дигідро-3Н-1,2,4-триазол-3-тіонами. Дослідження антимікробної активності синтезованих сполук демонструють потенціал пошуку антимікробних агентів серед зазначеного класу сполук.

scholarly journals Bacteria Sensitivity Pattern of Caesarean Section Wound on Selected Antibiotics in Ulin General Hospital Banjarmasin

2020 ◽  
Vol 16 (2) ◽  
pp. 73
Author(s):  
Nurhafizah Rafiani ◽  
Renny Aditya ◽  
Noor Muthmainah
Keyword(s):  
Escherichia Coli ◽  
Staphylococcus Aureus ◽  
Caesarean Section ◽  
Staphylococcus Epidermidis ◽  
Antibiotic Sensitivity ◽  
Cross Sectional ◽  
Surgical Wounds ◽  
Sensitivity Pattern ◽  
Antibiotic Sensitivity Test ◽  
Bacterial Sensitivity

Abstract: A cesarean delivery increases the risk of wound infection it should be prevented by using antibiotics. This study was to determine the pattern of bacterial sensitivity in surgical wounds of cesarean section patients for selected antibiotics, i.e ceftriaxone, cefixime, sulbactam ampicillin, ciprofloxacin, clindamycin and gentamicin.This observational study was conducted at the Ulin Public Hospital in Banjarmasin from July to September 2019. Using a cross sectional approach Samples of bacteria were identidied from 36 that were pusposively sampled, i.e., Staphylococcus aureus, Staphylococcus epidermidis and Escherichia coli. Antibiotic sensitivity test showed that Staphylococcus aureus was sensitive against gentamicin (100%),whereas Staphylococcus epidermidis and Escherichia coli. Were intermediately sensitive towards gentamicin (62.5%) and ceftriaxone (80%) Keywords: Antibiotic susceptibility, caesarean section, surgical wound

scholarly journals Incidence and sensitivity pattern of Klebsiella pneumoniae, Escherichia coli and Pseudomonas aeruginosa in a tertiary care hospital

2017 ◽  
Vol 6 (2) ◽  
pp. 329
Author(s):  
Anubhuti Khare ◽  
Saroj Kothari ◽  
Vaibhav Misra
Keyword(s):  
Escherichia Coli ◽  
Pseudomonas Aeruginosa ◽  
Klebsiella Pneumoniae ◽  
Tertiary Care ◽  
Care Hospital ◽  
E Coli ◽  
Medical College ◽  
Stewardship Program ◽  
Sensitivity Pattern ◽  
Indoor And Outdoor

Background: Antimicrobial resistance is a serious problem worldwide and differs from region to region. This study was planned to determine the incidence and sensitivity pattern of Klebsiella pneumoniae (K. pneumoniae), Escherichia coli (E. coli) and Pseudomonas aeruginosa (P. aeruginosa) in our region and discuss the general issues related to antimicrobial resistance.Methods: Prospective study was carried out between March to October 2015. Samples of urine, blood, pus, CSF and miscellaneous samples (fluids, swabs, sputum and stool) were collected from indoor and outdoor patients for isolation and antimicrobial susceptibility of K. pneumoniae, E. coli and P. aeruginosa in the Department of Microbiology G.R. Medical College, Gwalior (MP).Results: Out of the 5000 samples analyzed 1684 showed growth. K. pneumoniae (38.50%), E. coli (33.29%) and P. aeruginosa (28.19%) constituited a total of 805 isolates. Both E.coli and K. pneumoniae showed highest sensitivity for doxycycline (75%; 67% resp.) and second highest for levofloxacin (70%; 64% resp.), whereas, P. aeruginosa showed highest 57% sensitivity for amikacin followed by 48% for levofloxacin. β-lactam antibiotics and aminoglycosides showed high mean resistance (K.pneumoniae-83%, E.coli-79%, P. aeruginosa-86.4%) and (K. pneumoniae-75%, E. coli-61%, P. aeruginosa-70%) resp.Conclusions: The data indicates high resistance among the gram-negative bacteria for β-lactam and aminoglycoside antibiotics. Increasing resistance to doxycycline and flouroquinolones for K. pneumoniae and E. coli and multidrug resistance to P. aeruginosa is a cause of concern in this region. Thus, there is a need to stop misuse of antibiotics with immediate effect and to implement a strong antimicrobial stewardship program.

scholarly journals Profil Penggunaan Antibiotik dan Peta Kuman pada Pasien Gangren Diabetes Melitus di Sebuah RSUD di Kabupaten Gresik

2020 ◽  
Vol 3 (2) ◽  
pp. 96
Author(s):  
Isna Romadhona ◽  
Fauna Herawati ◽  
Rika Yulia
Keyword(s):  
Escherichia Coli ◽  
Staphylococcus Aureus ◽  
Pseudomonas Aeruginosa ◽  
Klebsiella Pneumoniae ◽  
Acinetobacter Baumannii ◽  
Proteus Mirabilis ◽  
Enterobacter Aerogenes ◽  
Enterobacter Cloacae ◽  
Proteus Vulgaris ◽  
Diabetes Melitus

Antibiotik merupakan obat yang digunakan untuk mengatasi dan mencegah infeksi bakteri. Penggunaan antibiotik yang tidak tepat dapat menimbulkan berbagai masalah, diantaranya pengobatan akan lebih mahal dan juga risiko terjadinya resistensi bakteri terhadap antibiotik. Penelitian ini bertujuan untuk mengetahui profil penggunaan antibiotik dan profil peta kuman pada pasien gangren diabetes melitus di sebuah RSUD di Kabupaten Gresik serta untuk mengetahui kesesuaian penggunaan antibiotik dengan mengacu pada Permenkes Republik Indonesia No. 2406/Menkes/PER/XII/2011. Data penggunaan antibiotik diperoleh dari catatan Rekam Medis pada periode Januari – November 2017. Data penggunaan antibiotik dihitung dengan menggunakan rumus DDD/100 pasien-hari rawat. Hasil perhitungan DDD/100 pasien-hari rawat menunjukkan hasil sebesar 470,11 DDD/100 pasien-hari rawat. Peta kuman pada pasien gangren, melaporkan adanya bakteri Enterobacter cloacae 24%, Escherichia coli 18%, Staphylococcus aureus 15%, Acinetobacter baumannii 9%, Pseudomonas aeruginosa 6%, Citrobacter youngae 6%, Enterobacter aerogenes 6%, Proteus vulgaris 6%, Staphylococcus schleiferi 6%, Klebsiella pneumoniae 3%, dan Proteus mirabilis 3% . Penggunaan antibiotik seftriakson dan metronidazol pada pasien gangren diabetes melitus di sebuah RSUD di Kabupaten Gresik pada periode Januari – November 2017 telah sesuai dengan pedoman penggunaan antibiotik berdasarkan Permenkes Republik Indonesia No. 2406/Menkes/PER/ XII/2011, yaitu antibiotik golongan sefalosporin generasi III yang lebih aktif terhadap Enterobacteriaceae dan antibiotik golongan nitroimidazol yang dapat mengobati infeksi bakteri basil anerob Gram-Negatif.

scholarly journals Avaliação da contaminação microbiana de cateteres venosos usados em pacientes hospitalizados.

2017 ◽  
Vol 16 (2) ◽  
pp. 167
Author(s):  
Cristiane Coimbra De Paula ◽  
Lisiane Vieira Paludetti ◽  
Walkiria Shimoya-Bittencourt
Keyword(s):  
Escherichia Coli ◽  
Staphylococcus Aureus ◽  
Pseudomonas Aeruginosa ◽  
Klebsiella Pneumoniae ◽  
Acinetobacter Baumannii ◽  
Stenotrophomonas Maltophilia ◽  
Terapia Intensiva

<p><strong>Introdução</strong>: as unidades de terapia intensiva frequentemente utilizam dispositivos invasivos, como os cateteres, os quais podem desencadear complicações como infecção e outros efeitos colaterais que são de grande importância na terapia clínica. Além disso, os cateteres venosos utilizados principalmente em unidades de terapia intensiva contribuem para disseminação de infecção hospitalar. <strong>Objetivo</strong>: avaliar os microrganismos causadores de infecções em ponta de cateter venoso usado nos pacientes hospitalizados na Santa Casa de Misericórdia de Cuiabá-MT. <strong>Metodologia</strong>: foi realizado um estudo transversal de natureza clínica, incluindo pacientes que tinham cateter venoso e excluídos os pacientes com sonda vesical. Foi utilizada a Técnica Semi quantitativa de Maki para cultivo e após o período de incubação, as placas com crescimento igual ou superior a 15 UFC, foram submetidas à identificação dos microrganismos através de provas bioquímicas. <strong>Resultados</strong>: foram analisadas 1.577 pontas de cateteres no ano de 2008, destas, 297 (18,8%) estavam infectadas, cujos microrganismos de maior prevalência foram em 46 (15,5%) pontas a presença de Escherichia coli, 59 (19,9%) da Pseudomonas aeruginosa, 43(14,5%) da Klebsiella pneumoniae, 42 (14,1%) de Staphylococcus sp coagulase negativa e 20 (6,7%) amostras apresentavam Staphylococcus aureus, dentre outros. Das 177 amostras de ponta de cateter analisadas em 2015, 45 (25,4%) estavam infectadas. Foram encontrados em 13 pontas (28,9%) a presença da bactéria Staphylococcus sp coagulase negativa e 8 (17,8%) da Pseudomonas aeruginosa, 5 (11,1%) da Klebsiella pneumoniae, 5 (11,1%) de Stenotrophomonas maltophilia, 4 (8,9%) de Acinetobacter baumannii <strong>Conclusão</strong>: pacientes internados podem ser expostos a cateteres venosos com significativo grau de contaminação microbiana</p>

scholarly journals Perfil microbiológico das culturas de pacientes internados na Sala de Cuidados Intermediários de um Hospital Universitário

2021 ◽  
Vol 10 (9) ◽  
pp. e38410918301
Author(s):  
Cleusa Wanderley de Queiroz Andrade ◽  
Katia Suely Batista Silva ◽  
Mirthes Maria Rodrigues Santana ◽  
Aline Vitória de Oliveira ◽  
Marcos Duarte Guimarães ◽  
...  
Keyword(s):  
Escherichia Coli ◽  
Pseudomonas Aeruginosa ◽  
Klebsiella Pneumoniae ◽  
Acinetobacter Baumannii ◽  
Enterobacter Cloacae ◽  
E Coli

Avaliar o perfil bacteriano das amostras de aspirados traqueais e uroculturas de pacientes internados na Sala de Cuidados Intermediários do Hospital Universitário do Vale do São Francisco, Petrolina/PE. Trata-se de um estudo descritivo, quantitativo e retrospectivo envolvendo a análise do perfil microbiológico das amostras coletadas no período de janeiro a dezembro de 2020 pelo Laboratório de Análises Clínicas do Hospital Universitário. Os dados foram tabulados em planilhas do Excel®, sendo feito a análise descritiva com valores percentuais e absolutos. As identificações bacterianas e os antibiogramas foram realizados através do sistema automatizado BD Phoenix ™, seguindo a metodologia do Clinical and Laboratory Standards Institute. Foram coletados 120 aspirados traqueais, sendo 55 positivos (46%) para achados bacterianos; os patógenos mais prevalentes foram: Acinetobacter baumannii (40%), Klebsiella pneumoniae (16%) e Pseudomonas aeruginosa (11%). Em relação às uroculturas, foram realizadas 183, sendo 10 (5,46%) positivas para achados bacterianos; as bactérias mais prevalentes foram: Escherichia coli (40%) e Enterobacter cloacae (20%). A. baumannii apresentou 100% de sensibilidade à colistina e polimixina B nos aspirados traqueias, assim como a K. pneumoniae apresentou à amicacina em todas as amostras coletadas. A E. coli demonstrou certa restência às cefalospororinas, com exceção da cefoxitina, sendo sensível; além disso, teve sensibilidade parcial ao sulfametoxazol+trimetoprima no estudo. O conhecimento do perfil microbiológico das bactérias permite a elaboração de protocolos preventivos e a realização de tratamento efetivos, diminuindo as taxas de mortalidade, o tempo de internação e os custos em saúde.

scholarly journals CLASSIFICATION OF GRAM-NEGATIVE BACILLI ACCORDING TO THEIR RESISTANCE TO ANTIMICROBIALS IN AN INFECTIOUS DISEASE CLINIC

2021 ◽  
Vol 24 (2) ◽  
pp. 83-86
Author(s):  
Lucian Giubelan ◽  
Keyword(s):  
Escherichia Coli ◽  
Pseudomonas Aeruginosa ◽  
Antibiotic Resistance ◽  
Klebsiella Pneumoniae ◽  
Acinetobacter Baumannii ◽  
Proteus Mirabilis ◽  
Multiple Criteria ◽  
Automated System ◽  
Gram Negative

Objectives. Classification on multiple criteria of Gram-negative bacilli (GNBs) according to antibiotic resistance. Material and method. Retrospective study (January 2017-December 2018) carried out in the Infectious Diseases Clinic from Craiova; GNBs were identified using the Vitek 2 automated system, which subsequently established their sensitivity to antimicrobials; GNBs were classified based on an arbitrary score from 1 (minimum) to 5 (maximum) based on the multiple antibiotic resistance index (MAR), the percentage of multidrug resistant strains (MDR) and the percentage of extended resistance strains (XDR). The final classification represents the sum of the points awarded for each category considered. Results. The following GNBs were considered: Escherichia coli (n = 720), Klebsiella pneumoniae (n = 335), Pseudomonas aeruginosa (n = 139), Proteus mirabilis (n = 60) and Acinetobacter baumannii (n = 29). MAR values are: Acinetobacter baumannii (Ab) – 0.6, Proteus mirabilis (Pm) – 0.52, Pseudomonas aeruginosa (Pa) – 0.51, Klebsiella pneumoniae (Kp) - 0.37 and Escherichia coli (Ec) – 0.23. The percentage of MDR strains is: Pm – 76.67%, Kp – 68.86%, Pa - 58.71%, Ec – 51.94% and Ab – 51.72%; XDR strains were identified for Ab - 17.24% and Pa – 6.47%. The final classification of GNBs is as follows: Pa – 12p, Ab - 11 p, Pm – 7p, Kp – 6p, Ec – 3p. Conclusions. Depending on the resistance profile on multiple criteria, the classification of the studied Gram-negative bacteria is as follows: Pa, Ab, Pm, Kp, Ec.

scholarly journals Detection of the KPC Gene in Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa, and Acinetobacter baumannii during a PCR-Based Nosocomial Surveillance Study in Puerto Rico

2011 ◽  
Vol 55 (6) ◽  
pp. 2968-2970 ◽  
Author(s):  
Iraida E. Robledo ◽  
Edna E. Aquino ◽  
Guillermo J. Vázquez
Keyword(s):  
Escherichia Coli ◽  
Pseudomonas Aeruginosa ◽  
Puerto Rico ◽  
Klebsiella Pneumoniae ◽  
Acinetobacter Baumannii ◽  
Surveillance Study ◽  
Beta Lactam ◽  
Content Type ◽  
Geographical Regions ◽  
Clinically Significant

ABSTRACTA 6-month, PCR-based, island-wide hospital surveillance study of beta-lactam resistance inEscherichia coli,Klebsiella pneumoniae,Pseudomonas aeruginosa, andAcinetobacter baumanniiwas conducted in Puerto Rico. Of 10,507 isolates, 1,239 (12%) unique, multi-beta-lactam-resistant isolates from all geographical regions were identified. The KPC gene was detected in 61E. coli, 333K. pneumoniae, 99P. aeruginosa, and 41A. baumanniiisolates, indicating the widespread dissemination of the KPC gene in clinically significant nosocomial isolates.

scholarly journals Ocorrência e perfil bacteriano de culturas coletadas em pacientes internados na unidade de terapia intensiva em um hospital terciário

HU Revista ◽  
2019 ◽  
Vol 45 (2) ◽  
pp. 122-133
Author(s):  
Carine Rosa Naue ◽  
Tércio Ribeiro ◽  
Rafaella Ribeiro ◽  
Katia Batista ◽  
Samuel Aquino
Keyword(s):  
Escherichia Coli ◽  
Staphylococcus Aureus ◽  
Pseudomonas Aeruginosa ◽  
Klebsiella Pneumoniae ◽  
Acinetobacter Baumannii ◽  
Enterobacter Cloacae ◽  
Terapia Intensiva

Introdução: O ambiente da UTI é considerado o foco das infecções relacionadas à assistência à saúde (IRAS). Isso deve-se a particularidades desse ambiente como a utilização de dispositivos invasivos, uso de imunossupressores, período de internação prolongado, colonização por micro-organismos resistentes, prescrição de antimicrobianos e a própria característica do ambiente da UTI, além da condição clínica do paciente. O conhecimento do perfil bacteriano de cada cultura norteia a equipe médica no tratamento inicial das infecções. Objetivo: O objetivo desse trabalho foi verificar a ocorrência e o perfil bacteriano presente em pacientes internados na UTI de um hospital universitário. Material e métodos: O estudo foi realizado através da análise de exames de secreções traqueais, hemoculturas e uroculturas de pacientes internados no período de janeiro a junho de 2018. Os dados foram coletados por meio de impressos laboratoriais do próprio serviço e tabulados na planilha do Excel®, sendo divididos em amostras positivas e negativas, e realizada análise descritiva com valores absolutos e percentuais. Resultados: Em geral, as bactérias de maior ocorrência foram Acinetobacter baumannii (20,3%), Pseudomonas aeruginosa (19,7%), Klebsiella pneumoniae (15,1%), Staphylococcus aureus (11,9%), Staphylococcus coagulase negativa (7,2%) e Escherichia coli (5,7%). As espécies bacterianas com maior resistência foram Acinetobacter baumanni, Klebisiella pneumoniae, aPseudomonas aeruginosa, Eschericia coli, Serratia marcencens e Enterobacter cloacae. Conclusão: Os dados deste trabalho permitem o conhecimento do perfil bacteriano encontrado nos pacientes internados, o que poderá nortear o tratamento das infecções e consequentemente diminuir a seleção de bactérias multirresistentes, auxiliando na prevenção e no controle das infecções hospitalares.

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