scholarly journals Bacteria Sensitivity Pattern of Caesarean Section Wound on Selected Antibiotics in Ulin General Hospital Banjarmasin

2020 ◽  
Vol 16 (2) ◽  
pp. 73
Author(s):  
Nurhafizah Rafiani ◽  
Renny Aditya ◽  
Noor Muthmainah
Keyword(s):  
Escherichia Coli ◽  
Staphylococcus Aureus ◽  
Caesarean Section ◽  
Staphylococcus Epidermidis ◽  
Antibiotic Sensitivity ◽  
Cross Sectional ◽  
Surgical Wounds ◽  
Sensitivity Pattern ◽  
Antibiotic Sensitivity Test ◽  
Bacterial Sensitivity

Abstract: A cesarean delivery increases the risk of wound infection it should be prevented by using antibiotics. This study was to determine the pattern of bacterial sensitivity in surgical wounds of cesarean section patients for selected antibiotics, i.e ceftriaxone, cefixime, sulbactam ampicillin, ciprofloxacin, clindamycin and gentamicin.This observational study was conducted at the Ulin Public Hospital in Banjarmasin from July to September 2019. Using a cross sectional approach Samples of bacteria were identidied from 36 that were pusposively sampled, i.e., Staphylococcus aureus, Staphylococcus epidermidis and Escherichia coli. Antibiotic sensitivity test showed that Staphylococcus aureus was sensitive against gentamicin (100%),whereas Staphylococcus epidermidis and Escherichia coli. Were intermediately sensitive towards gentamicin (62.5%) and ceftriaxone (80%) Keywords: Antibiotic susceptibility, caesarean section, surgical wound

scholarly journals Pola Kepekaan Bakteri Penyebab Pneumonia terhadap Antibiotika di Laboratorium Mikrobiologi RSUP Dr. M. Djamil Padang Periode Januari sampai Desember 2011

2015 ◽  
Vol 4 (2) ◽  
Author(s):  
Jaka Kurniawan ◽  
Erly Erly ◽  
Rima Semiarty
Keyword(s):  
Escherichia Coli ◽  
Staphylococcus Aureus ◽  
Research Method ◽  
Antibiotic Sensitivity ◽  
Secondary Data ◽  
Empiric Therapy ◽  
Test Results ◽  
Microbiology Laboratory ◽  
Sensitivity Pattern ◽  
Antibiotic Sensitivity Test

AbstrakPeningkatan resistensi bakteri penyebab pneumonia terhadap beberapa antibiotika yang lazim digunakan oleh klinisi dalam pemberian terapi empirik akan menyebabkan berkurangnya keefektifan terhadap terapi pneumonia. Hal ini akan berdampak semakin tingginya morbiditas dan mortalitas yang disebabkan oleh infeksi pneumonia. Tujuan penelitian ini adalah untuk mengetahui pola kepekaan bakteri penyebab pneumonia terhadap antibiotika di Laboratorium Mikrobiologi RSUP. Dr. M. Djamil Padang periode Januari 2011 - Desember 2011. Metode penelitian yang digunakan adalah deskriptif retrospektif terhadap data sekunder hasil uji kepekaan antibiotika dan jenis kuman dari 432 pasien, menunjukkan jenis bakteri penyebab pneumonia adalah Klebsiella sp, Streptococcus α haemolyticus, Staphylococcus aureus, Pseudomonas aeuruginosa, proteus sp, Basillus, Escherichia coli dan Enterobacter. Pola kepekaannya menunjukkan bahwa rata-rata semua bakteri tersebut mempunyai sensitivitas tertinggi terhadap Netilmicin, Meropenem, dan Sulbactam + Cefoperazone. Resistensi tertinggi ditunjukkan oleh Erithromycin, Ampicillin, Sulfamethroxazole + Trimethroprime,Tetracyclin, dan Choramphenicol.Kata kunci: antibiotika, bakteri penyebab pneumonia, pola kepekaan AbstractIncreased resistance of bacteria that cause pneumonia to some antibiotics that are commonly used by clinicians in the provision of empiric therapy, it will cause a reduction in the effectiveness of the treatment of pneumonia. This will lead to increasing morbidity and mortality caused by pneumonia infection. The objective of this study wass to determine the sensitivity pattern of bacteria that cause pneumonia to antibiotics in the Department of Microbiology Laboratory. Dr. M. Djamil Hospital Padang period from January 2011 to December 2011. The research method used was a descriptive and retrospective review of secondary data and antibiotic sensitivity test results of 432 patients types of germs. The results indicated the type of bacteria that cause pneumonia are Klebsiella sp, Streptococcus α haemolyticus, Staphylococcus aureus, Pseudomonas aeuruginosa, Proteus sp, Basillus, Escherichia coli, and Enterobacter. Sensitivity pattern showed that the average of all the bacteria has the highest sensitivity to Netilmicin, Meropenem, and Sulbactam + Cefoperazone, Highest resistance shown by Erithromycin, Ampicillin, Sulfamethroxazole Trimethroprime +, Tetracycline, and Choramphenicol.Keywords: antibiotics, the bacteria that caused pneumonia, sensitivity pattern

scholarly journals Pola Kepekaan Bakteri terhadap Antibiotik di Ruang Rawat Intensif RSPI Prof. Dr. Sulianti Saroso Jakarta

2017 ◽  
Vol 1 (2) ◽  
pp. 23
Author(s):  
Putriana Indah Lestari ◽  
Ika Susanti ◽  
Huda Rahmawati
Keyword(s):  
Escherichia Coli ◽  
Pseudomonas Aeruginosa ◽  
Klebsiella Pneumoniae ◽  
Acinetobacter Baumannii ◽  
Antibiotic Sensitivity ◽  
Secondary Data ◽  
Sensitivity Pattern ◽  
Important Health ◽  
Antibiotic Sensitivity Test ◽  
Antibiotics Sensitivity

Abstrak : Penyakit infeksi merupakan salah satu masalah kesehatan yang penting. Penggunaan antibiotik yang tidak rasional dan tepat guna pada pasien penyakit infeksi beresiko menyebabkan terjadinya resistensi. Tujuan dari penelitian ini yaitu untuk mengetahui pola kepekaan bakteri terhadap antibiotik pada pasien Ruang Rawat Intensif (ICU) RSPI Prof. Dr. Sulianti Saroso (RSPI-SS) Jakarta. Penelitian dilakukan deskriptif dan retrospektif terhadap data sekunder hasil uji kepekaan antibiotik dan jenis bakteri dari 107 pasien dalam kurun waktu 2011. Hasil menunjukkan 68 (65,4%) pasien mendapatkan hasil kultur positif dan uji kepekaan bakteri terhadap antibiotik. Jenis bakteri patogen yang dominan yaitu Acinetobacter baumannii (29,4%), disusul oleh Pseudomonas aeruginosa (27,9%), Klebsiella pneumoniae (13,2%) dan Escherichia coli (8,8%). Sebagian besar bakteri pada pasien ICU RSPISS telah berkurang kepekaannya (resisten) terhadap beberapa antibiotik. A. baumannii dan P. aeruginosa merupakan bakteri yang paling resisten terhadap antibiotik uji. Pola kepekaannya menunjukkan bahwa bakteri patogen mempunyai resistensi tertinggi terhadap erythromycin dan terendah terhadap amikasin.Infectious diseases is an important health problem. Irrational antibiotics usage is a leading cause in initiating drugs resistances. A preliminary study was conducted on the sensitivity pattern of microorganisms against antibiotics at the intensive care unit of Sulianti Infectious Diseases Hospital Jakarta. Retrospective. Secondary data were collected on the results of antibiotics sensitivity tests and species of microorganisms of 107 patients during the year 2011. Sixty eight (65,4%) patients were positive on microorganism culture test and tested on antibiotic sensitivity test. Predominance pathogenic species found were Acinetobacter baumannii (29,4%), followed by Pseudomonas aeruginosa (27,9%), Klebsiella pneumoniae (13,2%) and Escherichia coli (8,8%). Most species were less sensitive (resistant) to several antibiotics. The pattern of sensitivity showed that pathogenic microorganisms were the most resistant against erythromycin and the most sensitive antibiotics was amikacin.

Antibiotic Sensitivity Pattern of Bacterial Isolates from Different Clinical Specimens: Experience at NICVD, Dhaka

2012 ◽  
Vol 5 (1) ◽  
pp. 67-72 ◽  
Author(s):  
MS Shahidullah ◽  
MA Yusuf ◽  
Z Khatun ◽  
UKMN Ara ◽  
MT Mitul
Keyword(s):  
Escherichia Coli ◽  
Staphylococcus Aureus ◽  
Bacterial Infections ◽  
Antibiotic Sensitivity ◽  
Number Of Patients ◽  
Sensitivity Pattern ◽  
Pseudomonas Species ◽  
Severe Infections ◽  
Medical Wards ◽  
And Staphylococcus Aureus

Background: Infectious diseases are among the leading causes of death and sometimes curable.  Bacteria are the most common etiology in hospitalized patients. The objective of this study was to  evaluate the incidence of bacterial infections and their pattern of susceptibility to antibiotics in  moderate and severe infections in patients admitted at NICVD hospital.Methodology: The study was performed in the apical teaching hospital of Bangladesh situated at  Dhaka in the first half of 2012. Patients admitted in medical wards and medical ICU, suffering from  moderate and severe infections were studied. Clinical evaluation, routine and specific investigations  were done in each case. Microbiological samplings were tried on day 1, after completion of antibiotic  therapy or in between as required. Aerobic bacterial culture and sensitivity tests were done.  Result: A total of 274 cases were studied of which male (67.5%) were predominant than female  (32.5%). The highest number of patients were in the age group of 30-60 years (53.6%) followed by 10-  30 years (24.5%) and more than 60 years (12.8%). The mean age with standard deviation was  39.15±19.07 years (range 1-90 years). Most common isolated bacteria was the Pseudomonas species  (14.2%) followed by Escherichia coli (13.5%), Staphylococcus saprophyticus (6.9%) and Staphylococcus  aureus (2.2%). From these specimens Pseudomonas species (31.5%) was isolated mostly from pus. E.  coli was found most commonly in pus (16.3%) and urine (14.1%). Staph saprophyticus (13.0%) and  Staphylococcus aureus (4.3%) were both found most commonly in pus. Pseudomonas species was  100% resistant to Penicillin, Amoxycillin and Vancomycin. It was found that Pseudomonas species  was still more than 90% sensitive only to Imipenem. Escherichia coli was more than 80% sensitive to  only Imipenem and Amikacin. Staphylococcus aureus was sensitive to only Imipenem and Cephalexin.  Conclusion: In this study Pseudomonas species and Escherichia coli are the most common isolated  bacteria in this Institution. Most of the antibiotics are resistant to these two bacteria. DOI: http://dx.doi.org/10.3329/cardio.v5i1.12276 Cardiovasc. j. 2012; 5(1): 67-72

scholarly journals Antibiogram of the Common Uropathogenic Bacteria among Yemeni Patients in Sana’a City: A Recent Report

2018 ◽  
pp. 1-10 ◽  
Author(s):  
Hafez Alsumairy ◽  
Tawfique K. AlZubiery ◽  
Talal Alharazi ◽  
Mufeed Baddah ◽  
Adel Al-Zubeiry
Keyword(s):  
Escherichia Coli ◽  
Staphylococcus Aureus ◽  
Pseudomonas Aeruginosa ◽  
Empirical Therapy ◽  
High Sensitivity ◽  
Resistance Rate ◽  
Beta Lactam ◽  
Cross Sectional ◽  
Sensitivity Pattern ◽  
Uropathogenic Bacteria

Aims: This study aimed to identify the prevalence and antimicrobial susceptibility of the commonly isolated uropathogens in Sana’a city, Yemen. Study Design:  A cross-sectional and descriptive study. Place and Duration of Study: The study was carried out at the hospitals and clinics of Sana'a city, Yemen between October 2016 and March 2017. Methodology: Clean-catch mid-stream urine samples were collected to detect the most common uropathogenic bacteria and their antibiotic susceptibility using Kirby Bauer standardized method. Results: Urine cultures yielded 170 significant bacterial growths of uropathogens. Escherichia coli was the most often isolated pathogen (43.5%), followed by Klebsiella pneumoniae (24.7%), Pseudomonas aeruginosa (20.0%) and Staphylococcus aureus (11.8%). The overall sensitivity was high to an excellent pattern for Carbapenems, Nitrofurantoin, Amikacin, and Piperacillin-Tazobactam. Escherichia coli shows an excellent sensitivity (88%) for Nitrofurantoin and Imipenem, followed by (85%) Ertapenem. Pseudomonas aeruginosa exhibited moderate resistance to Carbapenems, Moxifloxacin, and Piperacillin-Tazobactam in this study. Staphylococcus aureus was more vulnerable to all Quinolones except Nalidixic acid and it displays a high sensitivity pattern, 90% for both Nitrofurantoin and Gentamicin, 83% for Penicillin, 80% for both Minocycline. Antibiogram of isolated organisms revealed that there was resistance to two and more antimicrobials. Conclusion: In this study, we observe a high resistance rates to Beta-lactam, Quinolones, and Macrolides antibiotics. Nevertheless, most uropathogenic isolates were still sensitive to Nitrofurantoin, Imipenem, Ertapenem, and Amikacin, they considered as a proper antibiotics for empirical therapy of UTIs. Establishment of antibiogram of locally isolated organisms is necessary to avoid indiscriminating use of antibiotic and to decrease the resistance rate in our community.

Molecular Characterization of Antibiotic Resistance Gene Pattern of Staphylococcus aureus and Escherichia coli in Mastitis Affected Dairy Cows

2020 ◽  
Author(s):  
T. Ramasamy ◽  
S. Keerthana ◽  
M.R. Srinivasan ◽  
D. Chandrasekar ◽  
K. Porteen ◽  
...  
Keyword(s):  
Escherichia Coli ◽  
Staphylococcus Aureus ◽  
Antibiotic Resistance ◽  
Antimicrobial Resistance ◽  
Molecular Characterization ◽  
Antibiotic Sensitivity ◽  
Growth Media ◽  
E Coli ◽  
Sensitivity Pattern

Background: Antimicrobial resistance is one of the latest challenges facing the scientific community. Raising the drug resistance is caused mainly by indiscriminate usage of antibiotics in human and animal subjects and the spread of antibiotic resistance between the two has an emerging global threat. Hence, current study aimed to study the antimicrobial resistance pattern and molecular detection of antibiotic resistance genes in Staphylococcus aureus and Escherichia coli isolated from mastitis affected cows. Methods: Milk samples from mastitis affected cows were subjected to antibiotic sensitivity test and screened for presence of Staphylococcus aureus and Escherichia coli using differential growth media. Molecular characterization of Staphylococcus aureus and Escherichia coli was done with the help of PCR by amplification of ‘nuc’ and ‘uspA’ gene respectively. MICs of Penicillin and Tetracycline were determined using microdilution method. Result: Antibiotic sensitivity pattern for Penicillin G, Ampicillin, Amoxycillin, Cefotaxime, Ceftriaxone, Azithromycin, Ciprofloxacin, Gentamicin, Oxytetracycline, Tetracycline and Vancomycin were 74.19%, 100%, 93.50%, 61.29%, 29%, 35.48%, 9.70%, 9.70%, 70.96% and 70.96% respectively. More than 87.90% of the S. aureus and 50% of the E. coli isolated were resistant to â-lactam antibiotics while 75% of the E.coli and 65.70% of the S. aureus isolated were resistant to Tetracycline antibiotics. The MICs of Penicillin for S.aureus and E.coli are 26.88 µg/ml and 13.54 µg/ml respectively and the MICs of Tetracycline for S. aureus and E. coli are 243.75 µg/ml and 960.93 µg/ml respectively which is 8-9 folds higher than the standard MICs. From the present study, it can be inferred that bovine mastitis cases are highly resistant to antimicrobial drugs. Results further indicate that Staphylococcus aureus and Escherichia coli are both resistant to Penicillin and Tetracycline with very high MIC.

scholarly journals Epidemiological and Bacteriological Profile of Urinary Tract Infection and the Antibiotic Sensitivity Pattern of Causative Organisms in National Medical College and Teaching Hospital - A Retrospective Cross-Sectional Study

Med Phoenix ◽  
2020 ◽  
Vol 5 (1) ◽  
pp. 40-45
Author(s):  
Sagar Ghimire ◽  
Sanjay Paudel ◽  
Shahrukh KC ◽  
Pragya Gautam ◽  
Vikash Paudel
Keyword(s):  
Escherichia Coli ◽  
Urinary Tract ◽  
Teaching Hospital ◽  
Antibiotic Sensitivity ◽  
Cross Sectional ◽  
National Medical College ◽  
Medical College ◽  
National Medical ◽  
Bacteriological Profile ◽  
Sensitivity Pattern

Background: Urinary tract infections (UTIs) are one of the most common infectious conditions seeking treatment. There are varieties of microorganisms associated. The bacteriological investigations are incomplete without antibiotic sensitivity test of the isolate. Our aim is to determine age and sex distribution of UTI, bacteriological profile, and antibiotic sensitivity pattern of the organisms. Materials and Methods: A retrospective cross-sectional observational study of records of patients with clinically suspected UTI from Kartik 2076 to Magh 2076 was conducted at National Medical College and Teaching Hospital (NMCTH). It included both inpatient and OPD visit patients who submitted their clean-catch midstream urine sample for culture and antibiotic sensitivity at Microbiology lab of NMCTH. Result: Out of 385 patients, 103 (26.75%) showed bacterial growth. Escherichia coli (47.58 %) was the most common organism followed by Staphylococcus sps. (18.45%) and Klebsiella sps.(17.47%) respectively. There was female dominance (62.13%) but male were predominantly affected in children and older population. The most common age group for UTI was 21-30 years (mean age 25 years) and females were more affected than males. The most common pathogen was Escherichia coli, followed by Staphylococcal sps. and Klebsiella. All the organisms showed best sensitivity to tigecycline (100%). Conclusion: This study highlights the common pathogens causing UTI and their antibiotic sensitivity patterns which could help clinicians in starting rational empirical antibiotic therapy for such patients while awaiting urine culture reports.   

scholarly journals Neonatal Septicemia: Isolation, Identification and Antibiotic Sensitivity Pattern of Bacteria in a Tertiary Hospital in Bangladesh

2017 ◽  
Vol 11 (2) ◽  
pp. 58-61
Author(s):  
Mahmuda Afrin ◽  
Md Abdullah Siddique ◽  
Abdullah Akhtar Ahmed ◽  
Md Nazrul Islam ◽  
Parimol Chandra Sarker ◽  
...  
Keyword(s):  
Staphylococcus Aureus ◽  
Brain Heart Infusion ◽  
Antibiotic Sensitivity ◽  
Gram Positive ◽  
College Hospital ◽  
Cross Sectional ◽  
Neonatal Septicemia ◽  
Microbiological Methods ◽  
Sensitivity Pattern ◽  
Highly Sensitive

A cross sectional descriptive study was done to find out the causative organisms and their antibiotic sensitivities in the Department of Microbiology in collaboration with the Department of Paediatrics, Rajshahi Medical College Hospital (RMCH), Rajshahi during the period of July 2014 to June 2015. A total of 116 blood samples were taken aseptically from patients who were suspected of neonatal septicemia. Blood was then inoculated in Brain heart infusion broth. Bacterial isolation, identification and antimicrobial susceptibility testing were done by standard microbiological methods. Among 116 cases, 33(28.4%) were found to be culture positive. The most commonly isolated causative agents of neonatal septicemia were Staphylococcus aureus 17(51.5%) followed by Escherichia coli 10(30.3%), Streptococcus pneumoniae 03(9.09%), Klebsiella pneumoniae 02(6.06%) and Pseudomonas aeruginosa 01(3.03%). In general, all the Gram positive and Gram negative isolates were highly sensitive to meropenem, amikacin, gentamicin and ciprofloxacin. Gram positive bacteria were found to be particularly sensitive to vancomycin. They were moderately sensitive to ceftazidime followed in amoxicillin but were totally resistant to ampicillin. This study revealed that Staphylococcus aureus and E.coli are predominant causative organisms in neonatal septicemia and these are highly sensitive to meropenem, amikacin, gentamicin and ciprofloxacin.Faridpur Med. Coll. J. Jul 2016;11(2): 58-61

scholarly journals Isolation and Identification and Antibiotics resistance of some Pathogenic bacteria from ants

2019 ◽  
Vol 17 (72) ◽  
pp. 55-60
Author(s):  
Sawsan Hassan Authman ◽  
Nibras Nazar Mahmood ◽  
Zaid Ra'ad Abas
Keyword(s):  
Escherichia Coli ◽  
Staphylococcus Aureus ◽  
Pathogenic Bacteria ◽  
External Surface ◽  
Antibiotic Sensitivity ◽  
Antibiotics Resistance ◽  
Isolation And Identification ◽  
Antibiotic Sensitivity Test ◽  
Internal Component ◽  
Klebsiella Spp

This study was carried out on 60 ants samples collected from different places included: Gardens House, Food, died Cockroaches and W.C. Two methods were used: Isolation of bacteria from external surface and internal component, that to show the importance of this insect and their role in transferring of pathogenic bacteria. The results showed isolation of 30 isolates of different bacterial genus at 50%, included Staphylococcus aureus at highest ratio 26.23% then Escherichia coli, Bacillus subtilis, Klebsiella spp., Proteus spp., Pseudomonas areuginosa and Sarcinia at (23.34, 13.34, 13.34, 10, 6.67, 6.67)% respectively. The study revealed that the ants ply an important role in transferring these microbes. The majority of that isolates were on their external surface 63.33% in comparison to that isolated from internal component. The antibiotic sensitivity test for isolates against (7) antibiotics were resistance to multi antibiotics specially Vancomycin, whilst most isolates were sensitive to Nitrofurantin.

scholarly journals UJI SENSITIVITAS BAKTERI PENYEBAB INFEKSI SALURAN KEMIH PADA PASIEN DIABETES MELITUS TERHADAP SEFTRIAKSON, LEVOFLOKSASIN, DAN GENTAMISIN

2016 ◽  
Vol 12 (2) ◽  
pp. 205
Author(s):  
Nova Octavianty Rachman ◽  
Muhamad Darwin Prenggono ◽  
Lia Yuli Budiarti
Keyword(s):  
Diabetes Mellitus ◽  
Escherichia Coli ◽  
Staphylococcus Aureus ◽  
Urinary Tract Infection ◽  
Urinary Tract ◽  
Tract Infection ◽  
Staphylococcus Epidermidis ◽  
Sensitivity Test ◽  
Cross Sectional ◽  
Diabetes Melitus

Abstract: Urinary Tract Infection (UTI) is a general term that indicates the presences or propagation of microorganism in urine. The urinary tract infection is a very common condition that occurs in both women and men of all ages. Diabetes Mellitus (DM) can lead to the development of bacteriuria. Bacterial resistance to antibiotics prolongs the UTI recover. The aim of this research was to find out bacterial sensitivity urinary tract infection in patients diabetes mellitus to selected antibiotic during July-September 2015. It was a descriptional study with cross-sectional. The subject of this research is all patients diabetes mellitus with urinary tract infection in internal medicine wards Ulin General Hospital Banjarmasin. The sampling technique in this research was a total sampling. The sensitivity test to antibiotic test in the research used Kirby Bauer method and analyzed according to CLSI 2013 standard.This type of bacteria found in this research are Escherichia coli, Pseudomonas aerugenosa, Staphylococcus epidermidis, and Staphylococcus aureus. The sensitivity test result the percentage type of bacteria are sensitive to ceftriaxone 73%, levofloxaxin 84,6%, and gentamicin 73%. The conclution is that most sensitive antibiotic is levofloxaxin (84,6%) Keywords: diabetes mellitus (DM), urinary tract infection (UTI), ceftriaxone, levofloxaxin, gentamicin. Abstrak: Infeksi Saluran Kemih (ISK) didefinisikan sebagai adanya infeksi bakteri dalam urin yang ditandai dengan bakteriuria bermakna. Infeksi saluran kemih merupakan kondisi yang sangat umum terjadi baik pada wanita maupun pria pada semua usia. Diabetes Melitus (DM) dapat menyebabkan perkembangan bakteriuria. Resistensi bakteri terhadap antibiotik menyebabkan lamanya penyembuhan dari ISK. Penelitian ini bertujuan mengetahui sensitivitas bakteri penyebab ISK pada pasien DM terhadap antibiotik terpilih periode Juli-September 2015. Penelitian ini merupakan penelitian deskriptif dengan pendekatan Cross Sectional. Subjek penelitian ini adalah seluruh pasien DM dengan ISK Rawat Inap di Bangsal Penyakit Dalam RSUD Ulin Banjarmasin. Teknik pengambilan sampel pada penelitian ini adalah Total Sampling. Uji sensitivitas bakteriuria terhadap antibiotik uji pada penelitian ini menggunakan metode Kirby-Bauer dan dianalisis secara deskriptif sesuai dengan standar CLSI 2013. Jenis bakteri yang ditemukan pada penelitian ini adalah Escherichia coli, Pseudomonas aerugenosa, Staphylococcus epidermidis, Staphylococcus aureus. Hasil uji sensitivitas menunjukkan bahwa presentase jenis bakteri yang sensitif terhadap Seftriakson 73%, Levofloksasin 84,6%, dan Gentamisin 73%. Persentase isolat bakteri yang resisten terhadap Seftriakson 15,3%, Levofloksasin 3,8%, dan Gentamisin 3,8%. Kesimpulan antibiotik yang paling sensitif terhadap bakteri penyebab ISK pada penilitian ini adalah Levofloksasin (84,6%). Kata-Kata kunci: diabetes melitus (DM), infeksi saluran kemih (ISK), seftriaxon, levofloksasin, gentamisin

scholarly journals Prevalence of Methicillin Resistant Staphylococcus aureus and Antibiotic Susceptibility Pattern in a Tertiary Hospital in Nepal

2018 ◽  
Vol 16 (2) ◽  
pp. 172-174 ◽  
Author(s):  
Laxmi Kant Khanal ◽  
Ram Prasad Adhikari ◽  
Ankita Guragain
Keyword(s):  
Staphylococcus Aureus ◽  
Methicillin Resistant Staphylococcus Aureus ◽  
Antibiotic Sensitivity ◽  
College Teaching ◽  
Tertiary Hospital ◽  
Cross Sectional Study ◽  
Resistance Pattern ◽  
Cross Sectional ◽  
Methicillin Resistant ◽  
Sensitivity Pattern

Background: Methicillin resistant Staphylococcus aureus is a global health challenge nowadays creating problem in antibiotic therapy. This study was aimed to generate resistance pattern of Methicillin resistant Staphylococcus aureus to various antibiotics in order to formulate antibiotic policy for control of Methicillin resistant Staphylococcus aureus in Nepal.Methods: This was a cross-sectional study conducted at the department of Clinical Microbiology, Nepal Medical College Teaching Hospital, from April 2015 to March 2016. A total of 142 S. aureus isolated from various clinical specimens. were screened for Methicillin resistant Staphylococcus aureus by cefoxitin disc method according to Clinical and Laboratory Standards Institute guidelines.Results: Out of 142 S. aureus isolates, 30 (21.1%) were detected as Methicillin resistant Staphylococcus aureus by cefoxitin disc method. Most of the Methicillin resistant Staphylococcus aureus (25/30) were isolated from pus which were collected from OPD patients. Antibiotic sensitivity pattern showed all Methicillin resistant Staphylococcus aureus isolates were sensitive to vancomycin.Conclusions: Prevalence of Methicillin resistant Staphylococcus aureus was found to be 21.1%, and all Methicillin resistant Staphylococcus aureus appear 100% sensitive to vancomycin. Keywords: .

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