scholarly journals Evaluación nutricional e indicadores bioquimicos en jóvenes universitarios de la provincia de Sánchez Carrión, región La Libertad

2018 ◽  
pp. 21-25
Keyword(s):  
Young People ◽  
Statistical Significance ◽  
Cross Sectional Study ◽  
Age Group ◽  
Sectional Study ◽  
High Altitudes ◽  
Anthropometric Measures ◽  
Cross Sectional ◽  
Blood Samples ◽  
Hb Concentration

Evaluación nutricional e indicadores bioquimicos en jóvenes universitarios de la provincia de Sánchez Carrión, región La Libertad  Anabel Doris González-Siccha1, Maria Virginia González Blas1, Roger Antonio Rengifo Penadillos1, Carmen Rosa Silva Correa1, Víctor Eduardo Villarreal La Torre1, George David González González2 1 Facultad de Farmacia y Bioquímica, Universidad Nacional de Trujillo, Av. Juan Pablo II s/n, Trujillo – Perú 2 Universidad Particular Antenor Orrego, Av. América Sur 3145 Monserrate, Trujillo -Perú Recibido 15 de junio del 2018. Aceptado 21 de junio del 2018 DOI: https://doi.org/10.33017/ECIPeru2018.0003/ Resumen Objetivo: Determinar la evaluación nutricional e indicadores bioquímicos en jóvenes universitarios de la Provincia de Sánchez Carrión, Región La Libertad. Material y Método: Estudio descriptivo, de corte transversal y prospectivo. Participaron 29 jóvenes (26 mujeres y 03 varones), de 17-29 años de ambos sexos, habitantes de Huamachuco. Antes de su inclusión en el estudio, se requirió firma del consentimiento informado. Se determinaron las medidas antropométricas empleando variables: peso (Kg), talla (cm) e Índice de Masa Corporal. Se tomaron muestras de sangre por punción del pulpejo del dedo, se determinó hemoglobina (método Cianometahemoglobina) y hematocrito (microcentrifugación). Resultados: Los valores promedios fueron hemoglobina =15.99±1.74; hematocrito =47,73±3,48, IMC=23,66±3,78; edad 19.07±.2,45. Tuvieron IMC normal 72.42%, sobrepeso 24.14% y obesidad 3.45% que podría deberse a una sobrenutrición y dieta rica en carbohidratos. El 62.07% tuvo hemoglobina elevada con IMC normal (44.83%), sobrepeso (13.79%), obesidad (3.45 %), y el 31.03% con hemoglobina normal, sin significancia estadística (x2=0.684; P>0.05. El grupo de 17-20 años de sexo femenino tuvo 62.07% de Hb elevada (policitemia fisiológica), pero la edad no influye en la concentración de Hb. (x2=5.151; P>0.05) pero si el sexo (x2=5.59; P<0.05). El 68.96% presento hematocrito elevado con IMC normal (55.17%), sobrepeso (13.79%) y hematocrito normal (el 31.03%) sin significancia estadística (x2=3.192; P>0.05). Del 68.96% con hematocrito elevado, la mayoría según grupo etario fue de 17-20 años (62.07%), (x2=0.787; P>0.05) y según el sexo fue 58.62% mujeres y el 10.34% varones (x2=1.487;P>0.05). En las altas altitudes se estimula la eritropoyesis en compensación a la disminución parcial del oxígeno elevando la hemoglobina y hematocrito, denominado policitemia fisiológica. Se concluye que, el mayor porcentaje de jóvenes presentan valores elevados de hemoglobina y hematocrito con IMC normal debido a las altas altitudes que estimulan la eritropoyesis. Descriptores: altas altitudes, hemoglobina, hematocrito, policitemia, IMC. Abstract Objective: To determine the nutritional evaluation and biochemical indicators in university students of the Province of Sánchez Carrión, La Libertad Region. Material and Method: Descriptive, cross-sectional study and  prospective. Participants 29 young people (26 women and 03 men), 17-29 years of both sexes, inhabitants of  Huamachuco. Prior to being included in the study, signed informed consent was required. It was determined the anthropometric measures using variables: weight (Kg), height (cm) and mass index bodily. Blood samples were taken by puncture of the finger pulp, hemoglobin was determined (method Cyanomethamoglobin) and   hematocrit (microcentrifugation). Results: The average values ​​were hemoglobin = 15.99 ± 1.74; hematocrit = 47.73 ± 3.48, BMI = 23.66 ± 3.78; age 19.07 ± .2.45. They had normal BMI 72.42%, overweight 24.14% and  obesity 3.45% that could be due to overnutrition and diet rich in carbohydrates 62.07% had high hemoglobin with normal BMI (44.83%), overweight (13.79%), obesity  (3.45%), and 31.03% with normal hemoglobin,  without statistical significance (x2 = 0.684, P> 0.05, the group of 17-20 years of female sex had 62.07% high Hb (physiological polycythemia), but age does not influence the  Hb concentration. (x2 = 5.151; P> 0.05) but if the sex (x2 = 5.59; P <0.05). 68.96% presented hematocrit  elevated with normal BMI (55.17%), overweight (13.79%) and normal hematocrit (31.03%) without significance statistics (x2 = 3.192; P> 0.05). Of 68.96% with elevated hematocrit, the majority according to age group was 17-20 years (62.07%), (x2 = 0.787, P> 0.05) and according to sex was 58.62% women and 10.34% males  (x2 = 1.487; P> 0.05). At high altitudes erythropoiesis is stimulated in compensation for the partial decrease of oxygen by elevating hemoglobin and hematocrit, called physiological polycythemia. It is concluded that, higher percentage of young people have high hemoglobin and hematocrit values ​​with normal BMI due to at high altitudes that stimulate erythropoiesis. Key words: high altitudes, hemoglobin, hematocrit, polycythemia, BMI, nutritional status.

scholarly journals Evaluación nutricional e indicadores bioquimicos en jóvenes universitarios de la provincia de Sánchez Carrión, región La Libertad

2018 ◽  
pp. 19-23
Keyword(s):  
Young People ◽  
Statistical Significance ◽  
Cross Sectional Study ◽  
Age Group ◽  
Sectional Study ◽  
High Altitudes ◽  
Anthropometric Measures ◽  
Cross Sectional ◽  
Blood Samples ◽  
Hb Concentration

Evaluación nutricional e indicadores bioquimicos en jóvenes universitarios de la provincia de Sánchez Carrión, región La Libertad Anabel Doris González-Siccha1, Maria Virginia González Blas1, Roger Antonio Rengifo Penadillos1, Carmen Rosa Silva Correa1, Víctor Eduardo Villarreal La Torre1, George David González González2 1 Facultad de Farmacia y Bioquímica, Universidad Nacional de Trujillo, Av. Juan Pablo II s/n, Trujillo - Perú 2 Universidad Particular Antenor Orrego, Av. América Sur 3145 Monserrate, Trujillo -Perú Recibido 15 de junio del 2018. Aceptado 21 de junio del 2018 Resumen Objetivo: Determinar la evaluación nutricional e indicadores bioquímicos en jóvenes universitarios de la Provincia de Sánchez Carrión, Región La Libertad. Material y Método: Estudio descriptivo, de corte transversal y prospectivo. Participaron 29 jóvenes (26 mujeres y 03 varones), de 17-29 años de ambos sexos, habitantes de Huamachuco. Antes de su inclusión en el estudio, se requirió firma del consentimiento informado. Se determinaron las medidas antropométricas empleando variables: peso (Kg), talla (cm) e Índice de Masa Corporal. Se tomaron muestras de sangre por punción del pulpejo del dedo, se determinó hemoglobina (método Cianometahemoglobina) y hematocrito (microcentrifugación). Resultados: Los valores promedios fueron hemoglobina =15.99±1.74; hematocrito =47,73±3,48, IMC=23,66±3,78; edad 19.07±.2,45. Tuvieron IMC normal 72.42%, sobrepeso 24.14% y obesidad 3.45% que podría deberse a una sobrenutrición y dieta rica en carbohidratos. El 62.07% tuvo hemoglobina elevada con IMC normal (44.83%), sobrepeso (13.79%), obesidad (3.45 %), y el 31.03% con hemoglobina normal, sin significancia estadística (x2=0.684; P>0.05. El grupo de 17-20 años de sexo femenino tuvo 62.07% de Hb elevada (policitemia fisiológica), pero la edad no influye en la concentración de Hb. (x2=5.151; P>0.05) pero si el sexo (x2=5.59; P<0.05). El 68.96% presento hematocrito elevado con IMC normal (55.17%), sobrepeso (13.79%) y hematocrito normal (el 31.03%) sin significancia estadística (x2=3.192; P>0.05). Del 68.96% con hematocrito elevado, la mayoría según grupo etario fue de 17-20 años (62.07%), (x2=0.787; P>0.05) y según el sexo fue 58.62% mujeres y el 10.34% varones (x2=1.487;P>0.05). En las altas altitudes se estimula la eritropoyesis en compensación a la disminución parcial del oxígeno elevando la hemoglobina y hematocrito, denominado policitemia fisiológica. Se concluye que, el mayor porcentaje de jóvenes presentan valores elevados de hemoglobina y hematocrito con IMC normal debido a las altas altitudes que estimulan la eritropoyesis. Descriptores: altas altitudes, hemoglobina, hematocrito, policitemia, IMC. Abstract Objective: To determine the nutritional evaluation and biochemical indicators in university students of the Province of Sánchez Carrión, La Libertad Region. Material and Method: Descriptive, cross-sectional study and prospective. Participants 29 young people (26 women and 03 men), 17-29 years of both sexes, inhabitants of Huamachuco. Prior to being included in the study, signed informed consent was required. It was determined the anthropometric measures using variables: weight (Kg), height (cm) and mass index bodily. Blood samples were taken by puncture of the finger pulp, hemoglobin was determined (method Cyanomethamoglobin) and hematocrit (microcentrifugation). Results: The average values were hemoglobin = 15.99 ± 1.74; hematocrit = 47.73 ± 3.48, BMI = 23.66 ± 3.78; age 19.07 ± .2.45. They had normal BMI 72.42%, overweight 24.14% and obesity 3.45% that could be due to overnutrition and diet rich in carbohydrates 62.07% had high hemoglobin with normal BMI (44.83%), overweight (13.79%), obesity (3.45%), and 31.03% with normal hemoglobin, without statistical significance (x2 = 0.684, P> 0.05, the group of 17-20 years of female sex had 62.07% high Hb (physiological polycythemia), but age does not influence the Hb concentration. (x2 = 5.151; P> 0.05) but if the sex (x2 = 5.59; P <0.05). 68.96% presented hematocrit elevated with normal BMI (55.17%), overweight (13.79%) and normal hematocrit (31.03%) without significance statistics (x2 = 3.192; P> 0.05). Of 68.96% with elevated hematocrit, the majority according to age group was 17-20 years (62.07%), (x2 = 0.787, P> 0.05) and according to sex was 58.62% women and 10.34% males (x2 = 1.487; P> 0.05). At high altitudes erythropoiesis is stimulated in compensation for the partial decrease of oxygen by elevating hemoglobin and hematocrit, called physiological polycythemia. It is concluded that, higher percentage of young people have high hemoglobin and hematocrit values with normal BMI due to at high altitudes that stimulate erythropoiesis. Key words: high altitudes, hemoglobin, hematocrit, polycythemia, BMI, nutritional status.

A cross-sectional study of adult attention deৎicit hyperactive disorder in patients with intentional self-harm

2020 ◽  
Vol 6 (1) ◽  
pp. 18-23
Author(s):  
Antarvedi Moshe ◽  
Kondepogu Ramesh Babu ◽  
Bathula Kalyan Rao
Keyword(s):  
Adult Adhd ◽  
Nuclear Family ◽  
Statistical Significance ◽  
Tertiary Hospital ◽  
Cross Sectional Study ◽  
Age Group ◽  
Sectional Study ◽  
Cross Sectional ◽  
Self Harm ◽  
Middle Socioeconomic Status

Attention deficit hyperactive disorder is previously known to be diagnosed in only childhood, recently many research has been done on ADHD, proving that ADHD can persist even in Adults. ADHD in adults is said to be one of the causes of suicide. The main aim of this Study is to identify the patients with intentional self-harm with their sociodemographic and clinical characteristics of the above patients and finally to determine the prevalence of Adult ADHD among high patients. It is a cross-sectional study of Patients who are above the age of 18 years, with intentional self-harm, who are willing to give consent for the Study, without any comorbid medical conditions and who came in contact with the outpatient department of psychiatry from other departments in a tertiary hospital between the timeline of 1 year (i.e. between 1st May 2015-30th April 2016). The subjects were recruited for Study, their sociodemographic details were collected, and SCID-I and SCID-II were applied along with Adult ADHD self-reporting scale. They were diagnosed according to DSM5 by two qualified Psychiatrist.Among the 112 patients who attended psychiatric OPD,45 of them were recruited for the Study with History of intentional self-harm, Mean age group of the Study was 28.27, and the study subjects were divided into two groups Intentional self Harm with ADHD and Intentional selfharm without ADHD, two groups were compared with each other, majority of them were between the Age group 21-30 yrs in both the groups(P=2.113), the preponderance of Female was seen in intentional self-harm without ADHD groups (p=4.544), subjects in this Study came from a semi-urban background, from both the groups (P=1.784), nuclear family (P=0.675) and middle socioeconomic status(6.585). The primary method used by subjects in both group (P=2.742)was multiple tablets with medium suicidal intent (p=1.044). When comparing both groups, no statistical significance could be found between them. This Study showed no statistically significant between Adult ADHD and Intentional Self Harm.

scholarly journals A cross sectional study on the precocious puberty among girls in the age group of 11-15 years, in two schools in Kollam

2017 ◽  
Vol 4 (5) ◽  
pp. 1603
Author(s):  
Jeffy Binu ◽  
Sonia Raichel Thomas
Keyword(s):  
Human Development ◽  
Precocious Puberty ◽  
Statistical Significance ◽  
Cross Sectional Study ◽  
P Value ◽  
Age Group ◽  
Sectional Study ◽  
Chi Square ◽  
Cross Sectional ◽  
Chi Square Test

Background: Puberty is the period during which human development progresses, from the first pubertal sign to full sexual maturation. Precocious puberty is a common problem affecting up to 29 per 100 000 girls per year. The objective of this study is to find out the prevalence of precocious puberty among school going girls and to find out relation with various risk factors.Methods: A cross sectional study was conducted by enrolling 250 school going girls by selecting one school each from urban and rural setup. Prevalence of precocious puberty was expressed in percentage and Chi square test was applied to check association. P value for statistical significance was fixed at P<0.05.Results: The prevalence of precocious puberty was found to be 10.4%. In urban it was found to be 12.35% and in rural it was 8.43%. Girls whose fathers have primary education are risky to have precocious puberty (P<0.049). Those students who take fish occasionally, that is once or thrice in a week were more prone to have precocious puberty (P<0.000). Prevalence of Precocious puberty is more in rural area when compared to urban area. Parents, especially fathers who were less educated should take of care of their daughter’s health by not giving them dried and junk foods. It is better to take fish daily, rather than once or thrice in a week, occasional consumption of fish is found to be a reason for precocious puberty.Conclusions: Prevalence of Precocious puberty was 10.4%. Fathers of the girls, who are not well educated and occasional fish consumption of girls was found to be the significant reason for Precocious puberty.

Suicidal Death Autopsy Analysis at Dhaka Medical College

1970 ◽  
Vol 40 (1) ◽  
pp. 18-21 ◽  
Author(s):  
MN Hossain ◽  
Z Rahman ◽  
S Akhter
Keyword(s):  
Forensic Medicine ◽  
Causes Of Death ◽  
Cross Sectional Study ◽  
Age Group ◽  
Sectional Study ◽  
Cross Sectional ◽  
Medical College ◽  
Autopsy Report ◽  
Common Causes ◽  
Suicidal Death

A cross sectional study was carried out at the department of Forensic Medicine in Dhaka Medical College during the period of January 2008 to December 2009. Data were collected from 3rd copy of the post mortem reports which were preserved in the department of Forensic Medicine with the verbal consent of the doctors who performed autopsy report. During this period total 5114 autopsies were conducted. Out of this 970 cases (19%) were suicidal in nature. It was noticed that all suicidal deaths occurred from 10 years to all age group respectively, but top amongst age group of suicidal deaths occurred in between 21 to 30 years of people. Suicidal deaths are more common in female than male. Suicidal deaths due to hanging is highest, next common causes of death due to organophosphorus compund poisoning. Suicidal deaths by hanging is more in female than male but in poisoning cases male are more lvictimised than female. Objectives of our study are to see the occurrence and methods of suicidal death. DOI: http://dx.doi.org/10.3329/bmj.v40i1.9957 BMJ 2011; 40(1): 18-21

End Organ Damage in Hypertensive Geriatric Age Group: A Cross Sectional Study

2017 ◽  
Vol 1 (3) ◽  
pp. 10-16
Author(s):  
Prakashkumar Kyada ◽  
Kunal Jadhav ◽  
T. K. Biswas ◽  
Varshil Mehta ◽  
Sojib Bin Zaman
Keyword(s):  
Ventricular Hypertrophy ◽  
Organ Damage ◽  
Cross Sectional Study ◽  
Left Ventricular ◽  
Age Group ◽  
Sectional Study ◽  
Isolated Systolic Hypertension ◽  
Cross Sectional ◽  
End Organ Damage ◽  
Common Risk Factors

Objective: Hypertension is one of the common risk factors for cardiovascular and cerebrovascular diseases/disorders A developing country like India faces the double burden of communicable and non-communicable diseases; of the which, hypertension is the most important treatable cause of mortality and morbidity with loss of functional capacity and decline in the quality of life. Aim: To study the prevalence of end organ damage in the hypertensive geriatric age group. Method: The present study was a cross sectional study, conducted in 150 elderly patients admitted in MGM Hospital, Navi Mumbai, India with the diagnosis of stage I or II hypertension from 2011 to 2013. Results: Data analysis of the present study showed that 68% of elderly population aged between 60 to 69 years were suffering from hypertension. Compared to males, females had a higher rate of target organ damage. This study found that out of all patients with total end organ damage, 54.6 % had CVS complications, 15.7 % had hypertensive retinopathy, 25.9 % and 18.51 had raised creatinine and proteinuria respectively. 19.4 % had cerebrovascular accident (CVA) complications. Among Cardiovascular related complications Coronary artery disease (CAD) was found in 21 patients, out of them 7 had Congestive cardiac Failure (CCF). Left Ventricular Hypertrophy (LVH) was the most common complication and seen in 38 patients. 13.8 % patients had Regional Wall Motion Abnormality (RWMA) Conclusion: The present study concluded that Isolated Systolic Hypertension (ISH) is the commonest type of hypertension in geriatric age group. This study concluded that the most common risk factors of HTN in the elderly are sedentary life style, dyslipidemia and extra salt intake while the most common end organ damage was observed to be Left Ventricular Hypertrophy followed by renal dysfunction. Keywords:  Hypertension,  Isolated Systolic Hypertension, Dyslipidemia.

HIGH PREVALENCE OF MALNUTRITON AND WORM INFECTION AMONG VAN KIEU AND PAKOH CHILDREN AGED 12-36 MONTHS IN DAKRONG DISTRICT, QUANG TRI PROVINCE

2012 ◽  
pp. 129-134
Author(s):  
Thi Lan Tran ◽  
Thi Huong Le ◽  
Xuan Ninh Nguyen
Keyword(s):  
Cross Sectional Study ◽  
Age Group ◽  
Infection Status ◽  
Sectional Study ◽  
Group Recommendation ◽  
Related Factors ◽  
Normal Children ◽  
Cross Sectional ◽  
High Prevalence ◽  
Very High

Objectives: Assess the nutritional status, worm infection status and some related factors among children aged 12-36 months of Dakrong district, Quang Tri province. Subject and method: A cross sectional study was carried out in 2010, in 680 children aged 12-36 months in 4 communes of Dakrong district, Quang Tri province. Results: The malnutrition rate was 55.0% for underweight, 66.5% for stunting and 16.2% for wasting. The prevalence of malnutrition increases by age group. The prevalence of worm infection was 31.6%, the highest prevalence was belong to Ascaris infection (24.6%), followed by Hookworm and Trichuris (6.5% and 6.2%, respectively). The prevalence of worm infection among children under two is very high (27.0%). The prevalence of worm infection was distributed quite equally between the malnutrition children group and normal children group. Recommendation: Early deworming forchildren from 12 months should be considered as important strategy against the malnutrition of children in Dakrong district, Quang Tri province

Perfil Epidemiológico de Pacientes Renais Crônicos em Tratamento Conservador em um Hospital Escola do Sul de Minas/ Epidemiological Profile of Chronic Renal Failure Patients on Conservative Treatment in a Hospital in Southern School of Minas

1970 ◽  
Vol 4 (4) ◽  
pp. 49-60
Author(s):  
Camila Dorilêo Negretti ◽  
Pablo Girardeli Mendonça Mesquita ◽  
Nilo César do Vale Baracho
Keyword(s):  
Diabetes Mellitus ◽  
Conservative Treatment ◽  
Cross Sectional Study ◽  
Age Group ◽  
Sectional Study ◽  
Cross Sectional ◽  
Control Programs ◽  
Keywords Epidemiology ◽  
Epidemiological Profile ◽  
Grade Iii

Objetivo: Determinar o perfil epidemiológico dos pacientes com Doença Renal Crônica em tratamento conservador no ambulatório do Hospital Escola de Itajubá. Materiais e Métodos: Estudo descritivo, de corte transversal, de abordagem quantitativa. Realizado com 171 pacientes atendidos em tratamento conservador no ambulatório de nefrologia no período de janeiro de 2012 a dezembro de 2013. A coleta objetivou caracterizar idade, sexo, raça, estado civil e procedência. Também foram avaliados dados do primeiro atendimento como: valores de ureia e creatinina, o grau de DRC, a etiologia e o número de retorno. Resultados: Dos doentes renais crônicos avaliados, 50,3% eram do sexo masculino, 88% da raça branca, 54,4% casados e a maioria (70,8%) possuía faixa etária prevalente >60 anos. A maioria dos atendidos, 98,5% pertence a microrregião de referência. Quanto a dados de primeira consulta, o diabetes mellitus foi a principal etiologia (38%). Os valores de ureia e creatinina acima da referência preconizada foi observado na maioria dos pacientes e o grau III de DRC em 31% dos casos. O número médio de retornos após a primeira consulta foi de três retornos em 25,13% dos pacientes. Conclusão: A pesquisa permitiu o conhecimento do perfil epidemiológico dos portadores de DRC em tratamento conservador. Os achados reforçam a necessidade de implementação de políticas voltadas para promoção e prevenção à saúde com divulgação de mais programas de controle para minimizar o surgimento de novos casos da DRC. Palavras-chave: Epidemiologia. Doença Renal Crônica. Tratamento. ABSTRACT.Objective: Determine the epidemiological profile of patients with Chronic Kidney Disease (CKD) on conservative treatment at the Hospital Escola de Itajubá. Materials and Methods: A retrospective, descriptive, cross-sectional study of quantitative approach. It was conducted with 171 patients who were treated in conservative treatment at the nephrology clinic from January 2012 to December 2013. The collection aimed to characterize age, sex, race, marital status and origin. We also evaluated data from the first service as: urea and creatinine values, the degree of CKD the etiology and the number of return. Results: Among the chronic renal patients evaluated, 50.3% were male, 88% Caucasian, 54.4% were married and the majority (70.8%) was the most prevalent age group> 60 years. Most of the patients 98.5% belong to micro region of reference. As the first appointment data, diabetes mellitus was the major cause (38%). The urea and creatinine values above the recommended reference was observed in the majority of patients and the DRC grade III in 31% of cases. The average number of returns after the fisrt visit was three return in 25.13% of patients. Conclusion: The research gave us the knowledge of the epidemiological profile of patients with CKD on dialysis. The findings reinforce the need to implement policies for health promotion and prevention with more disclosure of control programs to minimize the appearance of new cases of CKD. Keywords: Epidemiology. Chronic Kidney Disease.Treatment.

scholarly journals Comparison of capillary, venous and buffy coat blood samples in detecting Plasmodium species among malaria suspected patients attending at Hamusite health center. A cross-sectional study

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Getu Abeje ◽  
Woyneshet Gelaye ◽  
Getaneh Alemu
Keyword(s):  
Health Center ◽  
Detection Rate ◽  
Venous Blood ◽  
Cross Sectional Study ◽  
Buffy Coat ◽  
Blood Film ◽  
Capillary Blood ◽  
Sectional Study ◽  
Cross Sectional ◽  
Blood Samples

Abstract Background Both capillary and venous blood samples have been interchangeably used for the diagnosis of malaria in Ethiopia. However, Plasmodium parasites are thought to be more concentrated in capillary than in venous blood. Hence, selecting a sample source where parasites are more concentrated is indispensable approach in order to maximize the accuracy of blood film microscopy. Therefore, the present study aimed to compare the detection rate and the parasitemia level of Plasmodium species from conventional capillary and venous blood films, and buffy coat preparations. Methods A facility based cross-sectional study was conducted from Feburary to March 2020 among 210 febrile patients attending Hamusite health center, northwest Ethiopia. Capillary and venous blood samples were collected and buffy coat was prepared from each sample. Thin and thick blood films were prepared, stained, and examined microscopically following standard protocol. Data were analysed using Statistical Package for Social Sciences Software version 20 and Med-Calc software version 19.3. Results Capillary blood buffy coat (61/210, 29.0%) had significantly higher detection rate as compared to capillary (48/210, 22.9%) and venous (42/210, 20.0%) blood films (p < 0.001). However, no significant difference was observed between capillary and venous blood films (p = 0.070) in detecting Plasmodium species. The highest and the lowest mean asexual stage parasite counts were found in capillary blood buffy coat (4692.88) and venous blood (631.43) films, respectively showing significant variations (p < 0.001). Mean gametocyte count was also highest in capillary blood buffy coat (3958.44). As compared to capillary blood buffy coat, the sensitivity of venous blood buffy coat, capillary blood film and venous blood film were 73.8, 78.7, 68.9%, respectively. Conclusion Capillary blood buffy coat samples showed the highest sensitivity in detecting and quantitating malaria parasites that its use should be promoted in clinical settings. However, conventional capillary and venous blood films could be used interchangeably.

scholarly journals Cross-sectional study of preprints and final journal publications from COVID-19 studies: discrepancies in results reporting and spin in interpretation

BMJ Open ◽  
2021 ◽  
Vol 11 (7) ◽  
pp. e051821
Author(s):  
Lisa Bero ◽  
Rosa Lawrence ◽  
Louis Leslie ◽  
Kellia Chiu ◽  
Sally McDonald ◽  
...  
Keyword(s):  
Statistical Significance ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Journal Publication ◽  
Reporting Practices ◽  
Subgroup Analyses ◽  
Journal Publications ◽  
Study Characteristics ◽  
Results Reporting

ObjectiveTo compare results reporting and the presence of spin in COVID-19 study preprints with their finalised journal publications.DesignCross-sectional study.SettingInternational medical literature.ParticipantsPreprints and final journal publications of 67 interventional and observational studies of COVID-19 treatment or prevention from the Cochrane COVID-19 Study Register published between 1 March 2020 and 30 October 2020.Main outcome measuresStudy characteristics and discrepancies in (1) results reporting (number of outcomes, outcome descriptor, measure, metric, assessment time point, data reported, reported statistical significance of result, type of statistical analysis, subgroup analyses (if any), whether outcome was identified as primary or secondary) and (2) spin (reporting practices that distort the interpretation of results so they are viewed more favourably).ResultsOf 67 included studies, 23 (34%) had no discrepancies in results reporting between preprints and journal publications. Fifteen (22%) studies had at least one outcome that was included in the journal publication, but not the preprint; eight (12%) had at least one outcome that was reported in the preprint only. For outcomes that were reported in both preprints and journals, common discrepancies were differences in numerical values and statistical significance, additional statistical tests and subgroup analyses and longer follow-up times for outcome assessment in journal publications.At least one instance of spin occurred in both preprints and journals in 23/67 (34%) studies, the preprint only in 5 (7%), and the journal publications only in 2 (3%). Spin was removed between the preprint and journal publication in 5/67 (7%) studies; but added in 1/67 (1%) study.ConclusionsThe COVID-19 preprints and their subsequent journal publications were largely similar in reporting of study characteristics, outcomes and spin. All COVID-19 studies published as preprints and journal publications should be critically evaluated for discrepancies and spin.

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