DETERMINANT OF HEALTH PROTOCOL IMPLEMENTATION AMONG ELDERLY WITH CHRONIC DISEASE IN JEMBER

Background: Elderly is one of the vulnerable groups against COVID 19 infection. The mortality rate from COVID 19 is the highest in the elderly. The chronic disease is worsening the outcome. Objective: This study aimed to find the determinant of the implementation of health protocols among the elderly with chronic disease. Methods: This study was a correlational study conducted with a cross-sectional approach. A total of 437 elderly were selected through consecutive sampling techniques. The respondents were asked to fill the KAP questionnaire through a google form. The data were analysed using binary logistic regression and multivariate logistic regression techniques using SPSS. Result: The results showed that educational level (p-value 0,088); living arrangement (p-value 0,035); knowledge (p-value 0,026); occupation (p-value 0, 042) and the implementation of self-care management (p-value 0,047) were correlated with the implementation of health protocols among the elderly with chronic disease. Knowledge became the main determinant of the health protocol implementation among the elderly with OR 8,456 95%CI (3,495 – 20,455). Conclusion: It can be concluded that the elderly with adequate knowledge has the potential to be 8,4 times more likely to implement the health protocols properly. Health education about the appropriate implementation of health protocol needs to be carried out using a plain language that is easily accepted by the elderly

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Inappropriate Use of Antibiotics and Their Predictors in Pediatric Patients Admitted at the Hospital Central De Nampula, Mozambique

10.21203/rs.3.rs-786683/v1 ◽

2021 ◽

Author(s):

Sancho Pedro Xavier ◽

Audêncio Victor ◽

Graciano Cumaquela ◽

Melsequisete Daniel Vasco ◽

Osiyallê Rodrigues ◽

...

Keyword(s):

Logistic Regression ◽

Pediatric Patients ◽

Treatment Time ◽

Binary Logistic Regression ◽

Antibiotic Use ◽

P Value ◽

Binary Logistic Regression Analysis ◽

Duration Of Treatment ◽

Cross Sectional ◽

Inappropriate Use

Abstract Background Antibiotics are synthetic or natural substances used to treat diseases of infectious origin. When used incorrectly, they can be a factor in the development of antimicrobial resistance, increased treatment time, costs, and mortality. The present study aimed to assess the pattern inappropriate use of antibiotics and their predictors in pediatric patients admitted to the Hospital Central de Nampula, Mozambique Methods A cross-sectional, retrospective study with a quantitative approach was conducted between January and July 2019. The population consisted of children aged 0 to 10 years hospitalized in the pediatric ward I. Binary logistic regression was used to determine risk factors for inappropriate use of antibiotics with 95% CI. Results The prevalence of antibiotic use among pediatric patients was 97.5%. Of the 464 antibiotics prescribed, 39.9% were for patients suffering from gastroenteritis, 21.8% and 9.1% Affected with pneumonia and malaria. Most antibiotics were for systemic use (95.9%, 445/464). Most (36.5%) of prescriptions had errors. Duration of treatment (74.6%) and dosage (25.4%) were the most frequent errors. Binary logistic regression analysis revealed that patients were prescribed with ≥ 3 antibiotics (OR = 2.920, 95% CI = 1.283–6.646, p–value = 0.011) and with a short hospitalization time (OR = 1.726, 95% CI = 1.040–2.864, p–value = 0.035) were more likely to experience some inappropriate use of antibiotics. Conclusion The study showed a higher prevalence of antibiotic use, however, a greater number of prescriptions contained errors. Errors related to dose and duration of treatment were the most common among pediatric patients. These results reveal a concern, since inappropriate and excessive use of antibiotics is a major factor for the development of antibiotic resistant microorganisms. Therefore, strategies concerning the use of antibiotics in order to reduce their inappropriate and excessive use are necessary.

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COVID-19 health awareness among the United Arab Emirates population

PLoS ONE ◽

10.1371/journal.pone.0255408 ◽

2021 ◽

Vol 16 (9) ◽

pp. e0255408

Author(s):

Balsam Qubais Saeed ◽

Iffat Elbarazi ◽

Mai Barakat ◽

Ahmed Omer Adrees ◽

Kubais Saeed Fahady

Keyword(s):

Logistic Regression ◽

United Arab Emirates ◽

Online Survey ◽

Binary Logistic Regression ◽

P Value ◽

Binary Logistic Regression Analysis ◽

College Level ◽

Cross Sectional ◽

Correct Score ◽

Level Of Knowledge

In response to the global COVID-19 epidemic, the United Arab Emirates (UAE) government is taking precautionary action to mitigate the spread of the virus. The aim of this study was to evaluate the knowledge and practices toward COVID-19 among the general public in the UAE during the current outbreak. A cross-sectional online survey of 1356 respondents in the UAE was conducted during the epidemic outbreak between 9th to 24th June-2020. The questionnaire consisted of three sections: Socio-demographic, knowledge, practices. Independent-samples t-test, one-way analysis of variance (ANOVA), chi-square and binary logistic regression was used. A p-value of (p < 0.05) was considered statistically significant. The total correct score of knowledge and practice questions was high 85% and 90%, respectively. Male’s sex, other marital status, and illiterate/primary educational levels had a lower level of knowledge and practices than others. Participants aged 18–29 had little higher knowledge than other ages but had a lower level in practices, people who live in Abu Dhabi had better knowledge and practices than other emirates, employed people had a lower level of knowledge but higher in practices. Binary logistic regression analysis presented that females, 18–29 years, and married participants significantly associated with a higher score of knowledge, while female, over 30 years old, the martial status of singles, college-level and higher, unemployed, were significantly associated with high mean practices score. This study provided a full screening of the knowledge and practices among a sample of residents in The UAE toward COVID-19, continuing to implement the health education programs pursued by the UAE is highly important to maintain the appropriate level of awareness among the public.

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Development of predictive models for nutritional assessment in the elderly

Public Health Nutrition ◽

10.1017/s1368980020002153 ◽

2020 ◽

pp. 1-8

Author(s):

Belén Muñoz Díaz ◽

Jorge Martínez De La Iglesia ◽

Manuel Romero-Saldaña ◽

Rafael Molina-Luque ◽

Antonio P Arenas de Larriva ◽

...

Keyword(s):

Logistic Regression ◽

Diagnostic Accuracy ◽

Nutritional Assessment ◽

Mini Nutritional Assessment ◽

Binary Logistic Regression ◽

The Elderly ◽

Youden Index ◽

Screening Methods ◽

Multivariate Models ◽

Cross Sectional

Abstract Objective: To propose malnutrition screening methods for the elderly population using predictive multivariate models. Due to the greater risk of nutrition deficiencies in ageing populations, nutritional assessment of the elderly is necessary in primary health care. Design: This was a cross-sectional study. Multivariate models were obtained by means of discriminant analysis and binary logistic regression. The diagnostic accuracy of each multivariate model was determined and compared with the Chang method based on receiver operating characteristic curves. The optimal cut-point, sensitivity, specificity and Youden index were estimated for each of the models. Setting: The province of Cordoba, Spain. Participants: Two hundred fifty-five patients over the age of 65 years from three health centres and three nursing homes. Results: Fourteen models for predicting risk of malnutrition were obtained, six by discriminant multivariate analysis and eight by binary logistic regression. Sensitivity ranged from 55·6 to 93·1 % and specificity from 64·9 to 94 %. The maximum and minimum Youden indexes were 0·77 and 0·49, respectively. We finally selected a model which does not require a blood test. Conclusions: The proposed models simplify nutritional assessment in the elderly and, except for number 2 of those calculated by binary logistic regression, have better diagnostic accuracy than the Spanish version of the Mini Nutritional Assessment screening tool. The selected model, whose validation is necessary for the future with other different samples, provides good diagnostic accuracy, and it can be performed by non-medical personnel, making it an accessible, easy and rapid tool in daily clinical practice.

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Hubungan Tingkat Stres, Pengaruh Keluarga, dan Teman Sebaya dengan Status Merokok pada Mahasiswa Laki-Laki UIN Syarif Hidayatullah Jakarta Tahun 2019

Media Penelitian dan Pengembangan Kesehatan ◽

10.22435/mpk.v29i4.2025 ◽

2020 ◽

Vol 29 (4) ◽

Author(s):

Eva Dwiyanti Lestari ◽

Siti Ahlan Sarmadani ◽

Safira Hani Pratiwi ◽

Novera Nur Fikri ◽

Ahmad Solihin Hafi ◽

...

Keyword(s):

Logistic Regression ◽

Confidence Interval ◽

University Students ◽

Odds Ratio ◽

Smoking Status ◽

Binary Logistic Regression ◽

Male Students ◽

P Value ◽

Chi Square ◽

Cross Sectional

Abstract Smoking is an unhealthy behavior that causes high morbidity and mortality. In Indonesia the prevalence of smokers is still high, and the number of smokers among university students tends to increase. Smoking status among male students of Syarif Hidayatullah State Islamic University (UIN) Jakarta and factors related to smoking status behavior are not yet clearly known. This study was conducted to determine the relationship of stress levels, the influence of family and peers with smoking status on male students of UIN Syarif Hidayatullah Jakarta in 2019. This study used a cross sectional study design to determine the smoking status of male students of UIN Syarif Hidayatullah Jakarta. A purposive sampling technique was used to select 424 male university students. Data analysis was performed using the chi square test and binary logistic regression. The Results is the prevalence of smokers among male students of UIN Jakarta was 42.2%. The results of multivariate analysis showed that family and peers were significantly related to smoking status of students (p-value <0.05), while stress levels were not related. Odds ratio (OR) associated for family influence is 1.9 (95% Confidence Interval (CI): 1.24-2.93) and OR (95% CI) for with peer influence is 13.6 (6.20-29.81). The Conclusion is the prevalence of smokers is still quite high among male students at UIN Syarif Hidayatullah Jakarta. The influence factor of family and peers is related to smoking status of UIN Syarif Hidayatullah Jakarta student. Abstrak Merokok merupakan perilaku tidak sehat yang menyebabkan tingginya angka kesakitan dan kematian. Di Indonesia prevalensi perokok masih tinggi dan jumlah perokok di kalangan mahasiswa cenderung mengalami peningkatan. Status merokok mahasiswa Universitas Islam Negeri (UIN) Syarif Hidayatullah Jakarta dan faktor yang berhubungan dengan status merokok belum diketahui dengan jelas. Penelitian ini dilakukan untuk mengetahui hubungan tingkat stres, pengaruh keluarga, dan teman sebaya dengan status merokok pada mahasiswa UIN Syarif Hidayatullah Jakarta Tahun 2019. Penelitian ini menggunakan desain studi cross sectional untuk mengetahui status merokok mahasiswa laki-laki UIN Syarif Hidayatullah Jakarta. Teknik purposive sampling dilakukan untuk memilih 424 responden. Analisis data dilakukan dengan menggunakan uji chi square dan binary logistic regression. Hasil menunjukan prevalensi perokok pada mahasiswa laki-laki di UIN Syarif Hidayatullah Jakarta sebesar 42,2%. Hasil analisis multivariat menunjukkan bahwa keluarga dan teman sebaya berhubungan bermakna dengan status merokok mahasiswa (p-value <0,05), sedangkan level stres tidak berhubungan. Odds ratio (OR) untuk pengaruh keluarga sebesar 1,9 (95% Confidence Interval (CI): 1,24-2,93) dan OR (95% CI) untuk pengaruh teman sebaya sebesar 13,6 (6.20-29.81). Kesimpulannya adalah prevalensi perokok masih cukup tinggi pada mahasiswa laki-laki di UIN Syarif Hidayatullah Jakarta. Faktor pengaruh keluarga dan teman sebaya berhubungan dengan status merokok mahasiswa UIN Syarif Hidayatullah Jakarta.

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Hubungan Sikap dan Karakteristik Pasangan Usia Subur (PUS) dengan Keikutsertaan dalam Program KB di Wilayah Kerja UPT Puskesmas Sungai Raya Kecamatan Sungai Raya Kabupaten Aceh Timur

Serambi Saintia : Jurnal Sains dan Aplikasi ◽

10.32672/jss.v8i2.2424 ◽

2020 ◽

Vol 8 (2) ◽

pp. 105-114

Author(s):

Ainul Mardhiah ◽

Nova Hasbani Prima Dewi ◽

Aminy Aminy

Keyword(s):

Family Planning ◽

Family Planning Program ◽

The Elderly ◽

P Value ◽

Planning Program ◽

Elderly Age ◽

Chi Square ◽

Cross Sectional ◽

The Family ◽

Relationship Of

The family planning program also aims to improve the quality of the family in order to generate a sense of security, peace and hope of a better future in realizing the prosperity of birth and inner happiness. Allegedly the factor causing EFA participation in the family planning program is characteristic. The purpose of this research is to know the relationship of attitude and characteristic of Elderly Age Couple (PUS) with participation in family planning program at UPT Puskesmas Sungai Raya Sungai Raya District, East Aceh regency 2018. The research design used was analytic survey with cross sectional design. The population of this study is all Pairs Age of Fertile located in Work Area UPT Sungai Raya Public Health Service Center in January to December 2017 which amounted to 1897 people. Sampling using Slovin formula, obtained as many as 95 samples. The study was conducted from 7-17 July 2018 using questionnaires by interview. Statistical test using chi-square test. Result of research indicate that majority of fertile couple couples (PUS) participate in family planning program as much as 67 respondents (70,5%). Statistically there is relationship of attitude and characteristic of Elderly Age Couple (EFA) with non participation in family planning program in Working Area of UPT Puskesmas Sungai Raya Sungai Raya District of East Aceh Regency 2018 with p value <0,1. It is recommended that the family planning program holders in UPT Puskesmas Sungai Raya Sungai Raya District of East Aceh District to invite cross-sectoral figures to hold meetings to create mini workshop plans at least once a month to increase the participation of the Elderly Age Couple (PUS) in family planning programs. Keyword : Family Planning Program, Attitudes, CharacteristicsABSTRAKProgram KB juga bertujuan untuk meningkatkan kualitas keluarga agar dapat timbul rasa aman, tentram, dan harapan masa depan yang lebih baik dalam mewujudkan kesejahteraan lahir dan kebahagiaan batin. Diduga faktor yang menyebabkan ketidakikutsertaan PUS dalam program KB adalah karakteristik. Tujuan penelitian ini untuk mengetahui hubungan sikap dan karakteristik Pasangan Usia Subur (PUS) dengan keikutsertaan dalam program KB di Wilayah Kerja UPT Puskesmas Sungai Raya Kecamatan Sungai Raya Kabupaten Aceh Timur tahun 2018. Desain penelitian yang digunakan adalah survei analitik dengan rancangan bedah lintang. Populasi dari penelitian ini adalah seluruh Pasangan Usia Subur yang berada di Wilayah Kerja UPT Puskesmas Sungai Raya pada bulan Januari sampai dengan Desember tahun 2017 yang berjumlah 1.897 orang. Pengambilan sampel menggunakan rumus Slovin, didapatkan sebanyak 95 sampel. Penelitian dilaksanakan dari tanggal 7-17 Juli tahun 2018 menggunakan kuesioner dengan cara wawancara. Uji statistik menggunakan uji chi-square. Hasil penelitian menunjukkan bahwa mayoritas Pasangan Usia Subur (PUS) ikut serta dalam program KB yaitu sebanyak 67 responden (70,5%). Secara statistik ada hubungan sikap dan karakteristik Pasangan Usia Subur (PUS) dengan ketidakikutsertaan dalam program KB di Wilayah Kerja UPT Puskesmas Sungai Raya Kecamatan Sungai Raya Kabupaten Aceh Timur tahun 2018 dengan p value < 0,1. Sebaiknya pemegang program KB di UPT Puskesmas Sungai Raya Kecamatan Sungai Raya Kabupaten Aceh Timur agar mengajak tokoh lintas sektor agar mengadakan pertemuan untuk membuat rencana loka karya mini setidaknya satu bulan sekali untuk meningkatkan keikutsertaan Pasangan Usia Subur (PUS) dalam program KB.Kata Kunci : Program KB, Sikap, Karakteristik

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Is there a relationship between gestational diabetes and postpartum depression?

Current Women s Health Reviews ◽

10.2174/1573404816999200918115133 ◽

2020 ◽

Vol 16 ◽

Author(s):

Salman Khazaei ◽

Erfan Ayubi ◽

Saeid Bashirian ◽

Ronak Hamzehei ◽

Ensiyeh Jenabi

Keyword(s):

Gestational Diabetes ◽

Postpartum Depression ◽

Odds Ratio ◽

Depression Scale ◽

Binary Logistic Regression ◽

Cross Sectional Study ◽

University Education ◽

P Value ◽

Cross Sectional ◽

The Relationship

Background: The relationship between gestational diabetes and postpartum depression (PPD) is poorly understood and seldom studied. Objective: In an effort to explore this issue, the present study investigated the relationship between gestational diabetes and PPD. Methods: The present cross-sectional study was performed with 342 women who were referred to four urban health centers of Hamadan city, west of Iran. We used convenience sampling as a method to recruit women in each health center. We used a researcher-made checklist for gathering data on socio-demographic characteristics and potential risk factors of PPD. The Persian validated version of the Edinburgh Postnatal Depression Scale (EPDS) was used to assess PPD. Univariate and multivariable binary logistic regression was applied to estimate the odds ratio (OR) (95% confidence interval [CI]). Results: Gestational diabetes was identified as the most important risk factor for PPD with OR (95% CI) of 2.19 (1.11, 4.31); P-value=0.02 after adjusting for other variables. Moreover, the adjusted odds ratio showed that PPD among lesseducated women (primary school) was 3.5 times higher compared to women with a university education (OR=3.54, 95% CI: 1.27, 9.84; P-value=0.01). Conclusion: Our findings suggested that PPD is more likely among women with gestational diabetes and those who were less educated. Interventional and educational activities for reducing the risk of PPD can be targeted for use with this population.

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Several Components of the Lebanese Mediterranean Diet and Particular Sociodemographic, Medical and Lifestyle Factors may be Associated with Gastroesophageal Reflux Disease in Adults: A Cross-sectional Study in a Middle Eastern Setting

Current Nutrition & Food Science ◽

10.2174/1573401316999200518095448 ◽

2020 ◽

Vol 17 (1) ◽

pp. 82-93

Author(s):

Mary-Joe Youssef ◽

Antoine Aoun ◽

Aline Issa ◽

Lana El-Osta ◽

Nada El-Osta ◽

...

Keyword(s):

Logistic Regression ◽

Gastroesophageal Reflux Disease ◽

Perceived Stress ◽

Dietary Habits ◽

Cross Sectional Study ◽

Lifestyle Factors ◽

P Value ◽

Sectional Study ◽

Cross Sectional ◽

Gerd Symptoms

Background: The prevalence of gastroesophageal reflux disease (GERD) is increasing worldwide and the related chronic symptoms can be associated with morbidity and poor quality of life. Objective: The objective of this study was to identify foods and beverages consumed by the Lebanese population, dietary habits, socio-demographic and lifestyle factors, health parameters and perceived stress, implicated in increasing GERD symptoms. Methods: This observational cross-sectional study was carried among Lebanese adults in 2016. A convenient sample of 264 participants was equally divided into a GERD group and a control group. Data on socio-demographic characteristics, lifestyle, health status and dietary habits including Lebanese traditional dishes were collected. The perceived stress scale (PSS) was also used to assess the participants’ perception of stress. Logistic regression analyses were conducted with GERD symptoms (presence or absence) being the dependent variable. Results: The GERD symptoms were significantly associated with age (-p-value=0.017), family history of GERD symptoms (-p-value<0.001), smoking (-p-value=0.003) and chronic medical conditions (-p-value<.001). Regarding the dietary factors, participants who ate three meals or less/day, between meals and outside homes were 2.5, 2.9 and 2.4 times at a higher risk of experiencing GERD symptoms than others, respectively. Moreover, the logistic regression model showed that the GERD symptoms were significantly associated with the consumption of coffee (-p-value=0.037), Lebanese sweets (-p-value=0.027), fried foods (-p-value=0.031), ‘Labneh’ with garlic (-p-value<0.001), pomegranate molasses (-p-value=0.011), and tomatoes (-p-value=0.007). Conclusion: Some specific lifestyle factors and components of the Lebanese Mediterranean diet could be associated with GERD symptoms.

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Budaya Kerja Petugas Panti Menurut Persepsi Lansia Dengan Kejadian Pengabaian di PSTW X

Jurnal Endurance ◽

10.22216/jen.v4i3.3776 ◽

2019 ◽

Vol 4 (3) ◽

pp. 651

Author(s):

Lola Felnanda Amri

Keyword(s):

Logistic Regression ◽

Nursing Home ◽

Work Environment ◽

The Elderly ◽

Statistical Test ◽

Nursing Personnel ◽

Work Culture ◽

Chi Square ◽

Cross Sectional ◽

Correlation Design

Perawatan pada lansia di panti tresna werdha X dilakukan berdasarkan rutinitas kerja dan petugas belum mendapat pelatihan mengenai kebutuhan dasar lansia yang harus dipenuhi. Berdasarkan hal tersebut, peneliti ingin mengetahui hubungan budaya kerja petugas panti menurut persepsi lansia dengan kejadian pengabaian di PSTW X Sumatera Barat. Desain penelitian deskriptif korelasi, menggunakan pendekatan cross sectional. Pengambilan sampel dengan total sampling, berjumlah 75. Uji statistik digunakan chi square dan regresi logistik. Hasil yang diperoleh seluruh lansia mengalami pengabaian; ada hubungan antara sikap terhadap apa yang dikerjakan, lingkungan pekerjaan; waktu dengan pengabaian lansia; Tidak ada hubungan antara perilaku ketika mengambil keputusan dengan pengabaian lansia. Sikap terhadap apa yang dikerjakan memiliki pengaruh paling besar terhadap kejadian pengabaian lansia. Disimpulkan bahwa petugas harus lebih memahami tentang peran dan fungsinya sebagai pemberi pelayanan pada lansia. Direkomendasikan agar pejabat yang berwenang dapat menempatkan petugas panti sesuai dengan peran dan fungsi serta kewenangannya, dan merekrut perawat sesuai dengan kebutuhan panti. The nursing of elderly in Tresna Werda X nursing home is mainly based on the workrout in and that the caregiver have not yet received training on the basic needs of the elderly that they should meet. Therefore, the researcher wanted to know the relations of the work culture of caregiver according to the elderly’s perception with the incidence of neglect in PSTW X West Sumatera. This study used Descriptive correlation design with cross sectional approach. The method of sampling used total sampling, which amounts to 75. The statistical test used chi square and logistic regression. The results of the study show that all of the elderly experienced neglect; there is a relation between attitude towards what is conducted, work environment, time with elderly neglect; no relation between behavior in making decisions with elderly neglect. The attitude towards what is conducted has the most impacton the incidence of elderly neglect. It is concluded that the caregiver should have a better understanding on their roles and functions as the caregivers to the elderly. Moreover, it is recommended that the authorities should put nursing personnel in accordance with the roles, functions and competence, and recruit nurses in accordance with the needs of the nursing home.

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Cross-Sectional Association between Hypercholesterolemia and Knee Pain in the Elderly with Radiographic Knee Osteoarthritis: Data from the Korean National Health and Nutritional Examination Survey

Journal of Clinical Medicine ◽

10.3390/jcm10050933 ◽

2021 ◽

Vol 10 (5) ◽

pp. 933

Author(s):

Byung Woo Cho ◽

Du Seong Kim ◽

Hyuck Min Kwon ◽

Ick Hwan Yang ◽

Woo-Suk Lee ◽

...

Keyword(s):

Logistic Regression ◽

Regression Analysis ◽

Knee Pain ◽

Logistic Regression Analysis ◽

National Health ◽

Large Scale ◽

Metabolic Diseases ◽

The Elderly ◽

Cross Sectional ◽

Ordinal Logistic Regression Analysis

Few studies have reported the relationship between knee pain and hypercholesterolemia in the elderly population with osteoarthritis (OA), independent of other variables. The aim of this study was to reveal the association between knee pain and metabolic diseases including hypercholesterolemia using a large-scale cohort. A cross-sectional study was conducted using data from the Korea National Health and the Nutrition Examination Survey (KNHANES-V, VI-1; 2010–2013). Among the subjects aged ≥60 years, 7438 subjects (weighted number estimate = 35,524,307) who replied knee pain item and performed the simple radiographs of knee were enrolled. Using multivariable ordinal logistic regression analysis, variables affecting knee pain were identified, and the odds ratio (OR) was calculated. Of the 35,524,307 subjects, 10,630,836 (29.9%) subjects experienced knee pain. Overall, 20,290,421 subjects (56.3%) had radiographic OA, and 8,119,372 (40.0%) of them complained of knee pain. Multivariable ordinal logistic regression analysis showed that among the metabolic diseases, only hypercholesterolemia was positively correlated with knee pain in the OA group (OR 1.24; 95% Confidence Interval 1.02–1.52, p = 0.033). There were no metabolic diseases correlated with knee pain in the non-OA group. This large-scale study revealed that in the elderly, hypercholesterolemia was positively associated with knee pain independent of body mass index and other metabolic diseases in the OA group, but not in the non-OA group. These results will help in understanding the nature of arthritic pain, and may support the need for exploring the longitudinal associations.

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Serum sodium in relation to various domains of cognitive function in the elderly US population

BMC Geriatrics ◽

10.1186/s12877-021-02260-4 ◽

2021 ◽

Vol 21 (1) ◽

Author(s):

Sohyae Lee ◽

Jin-young Min ◽

Beom Kim ◽

Sang-Won Ha ◽

Jeohng Ho Han ◽

...

Keyword(s):

Executive Function ◽

Cognitive Function ◽

Serum Sodium ◽

Verbal Memory ◽

The Elderly ◽

Cognitive Change ◽

Cognitive Test ◽

P Value ◽

Digit Symbol Substitution Test ◽

Cross Sectional

Abstract Background Recent evidence suggests that sodium imbalances may be associated with cognitive impairment; however, the association between specific domains of cognition remains unclear. This study examines the association between serum sodium levels and immediate and delayed verbal memory as measured by the CERAD Word Learning Test (CERAD WLT), executive function as measured by the Animal Fluency test (AFT), and sustained attention, working memory, and processing speed as measured by the Digit Symbol Substitution test (DSST) in the elderly population of the US aged 60 and older who participated in the 2011–2014 National Health and Nutrition Examination Surveys (n = 2,541). Methods Cognitive function tests were performed by trained interviewers and sodium levels were measured using indirect ion selective electrode methodology. Results After adjusting for all covariates, quintiles of CERAD WLT scores showed significant positive associations with log-transformed sodium levels (Immediate recall (IR) β = 4.25 (SE = 1.83, p-value 0.027); Delayed recall (DR) β = 6.54 (SE = 1.82, p-value 0.001)). Compared to normal sodium levels, hyponatremia was significantly associated with lower CERAD WLT-IR (β = -0.34, SE = 0.15, p-value 0.035) and CERAD WLT-DR scores (β -0.48, SE = 0.10, p-value < 0.001) and showed borderline significance with AFT scores (β = = -0.38, SE = 0.19, p-value 0.052). Hypernatremia did not show any significant relationships with cognitive test scores, compared to normal sodium levels. Conclusions Our cross-sectional study showed that lower sodium levels were associated with cognitive change, especially regarding memory and executive function.

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